OpenLLM-France/wikimedia huggingface dataset:
# Cymserine

Cymserine is a drug related to physostigmine, which acts as a reversible cholinesterase inhibitor, with moderate selectivity (15×) for the plasma cholinesterase enzyme butyrylcholinesterase, and relatively weaker inhibition of the better-known acetylcholinesterase enzyme. This gives it a much more specific profile of effects that may be useful for treating Alzheimer's disease without producing side effects such as tremors, lacrimation, and salivation that are seen with the older nonselective cholinesterase inhibitors currently used for this application, such as donepezil. A number of cymserine derivatives have been developed with much greater selectivity for butyrylcholinesterase, and both cymserine and several of its analogues have been tested in animals, and found to increase brain acetylcholine levels and produce nootropic effects, as well as reducing levels of amyloid precursor protein and amyloid beta, which are commonly used biomarkers for the development of Alzheimer's disease (potentially indicating the drugs as candidates to be the first medicine capable of stopping, and even reversing, the progression of the disease).
Unfortunately, the extremely promising results of cymserine administration in Alzheimer's patients is hindered by its toxic metabolites. A portion of administered cymserine is metabolized in the body into eseroline, a potent mu opioid agonist and neurotoxin. As such, derivatives of cymserine which share its effects and mechanism of action but differ in their metabolic pathways would theoretically produce much fewer side-effects and have a greatly reduced risk of neurotoxic damage occurring with long-term administration (which could ultimately result in a greater loss of mental capacity than Alzheimer's itself). The search for cymserine derivatives which do not serve as prodrugs to eseroline is ongoing.
# Govind Sharma

Govind Sharma (born 10 October 2002) is an Indian cricketer. He made his first-class debut for Jammu & Kashmir in the 2018–19 Ranji Trophy on 7 January 2019.
# MV ID Integrity

MV ID Integrity is a 26,070 gross ton, 45,653 deadweight ton bulk carrier, built in 1996 and managed by ID Wallem, Hong Kong. The ship was disabled and was in danger of hitting the Great Barrier Reef on 19 May 2012.
# Archie Hamilton (DJ)

Archie Hamilton is a DJ, producer and label owner based in London. He has released on labels such as Fear of Flying, Fasten Musique Concrete and his own imprints Moscow Records, Moss Co. & Arkityp.

## Early career

In 2008 Hamilton graduated from Oxford Brookes University with a degree in Marketing Management. Following this he completed an introductory production course at Point Blank Music School. His tutor was Chad Jackson, who wrote the 90's hit “Hear The Drummer (Get Wicked)." Here he learned the basics of sequencing. After moving to London at the age of 18, Hamilton started as a regular partygoer to several London venues whilst producing tracks in his bedroom. Eventually his work was noticed by the DJs playing at FUSE, a Sunday party held at the Shoreditch club, 93 Feet East. This led to him being asked to play there for the first time in 2013 and eventually becoming a resident.

## Record labels
### Moscow Records

Moscow Records was started in December 2009 as a platform for Hamilton to release his own music. The labels first release was called ‘Introductions EP Part 1’ featuring tracks from Archie himself, Keinton & Alexqbit. This was the first in a series of EPs released focused on showcasing up and coming producers. Since then artists such as Enzo Siragusa, 100 Hz and Benson Herbert have released on the label.

### Moss Co.

Established in 2013 Moss Co. was started as a new creative venture releasing more experimental music than Moscow Records. Its inception was the result of Moscow's distributor almost going into administration and the cost of pressing vinyl being too high to continue. Releases on Moss Co. have been charted by Maher Daniel, Julie Marghilano, Enzo Siragusa & Archie Hamilton.

## Present day

In 2015 Hamilton released the commercially successful singles ‘Mind Blank’ and ‘Works On Sunday’ on FUSE. The summer saw the launch of a new project, ‘Arkityp’ with fellow FUSE London resident, Rossko, hosting five events in the summer season at Ibiza's Underground Club. Arkityp was continued as a label reserved for collaborations by Hamilton & Rossko. That year he also played at the Sonus festival in Croatia, at Gottwood and OFF Sonar.
He has played at clubs in Australia, Asia and North and South America.
# Vadna

Vadna is a village in Borsod-Abaúj-Zemplén county, Hungary.

## Etymology

The name comes from Slavic/Slovak vodná derived from voda (water). Wodna (1237—1242, falsum dated to 1237).
# Titus Quinctius Crispinus Valerianus

Titus Quinctius Crispinus Valerianus was a Roman senator, who was active during the reign of Augustus. He was suffect consul in the second half of AD 2 as the colleague of Publius Cornelius Lentulus Scipio.
Crispinus Valerianus was of Patrician descent, but his familial connections beyond that are unclear. He could be the biological son of a Valerius who was adopted by Titus Quinctius Crispinus Sulpicianus, one of the alleged lovers of Julia the Elder; or the son of a Quinctius Crispinus and a Valeria; or even the brother of Crispinus Sulpicianus.
One certain event in his life is the date of his praetorship, which was in 2 BC; this allows us to infer he acceded to the consulate anno suo, and fixing the year of his birth as 32 BC. We know that he was a member of the Arval Brethren, for inscriptions confirm his presence at their ceremonies from AD 14 through 27. He likely died before the end of the reign of Tiberius.
# Chiu Tai-yuan

Chiu Tai-yuan (Chinese: 邱泰源; born 30 October 1956) is a Taiwanese physician and politician who currently serves as the Health and Welfare Minister.

## Education

Chiu enrolled in China Medical University in 1976 and graduated with his Doctor of Medicine in 1983. He then earned a Master of Health Science from the University of Tokyo in 1995.

## Political career

In 2015, Chiu was nominated by the Democratic Progressive Party (DPP) for the proportional representation constituency in the 2016 Taiwanese legislative election, listed 22nd in the party-list, but was not elected.
In October 2016, after legislator Hsu Kuo-yung transfer to the Executive Yuan serving as spokesperson, Chiu was elected by substitute. Chiu was re-elected in 2020.
On 19 April 2024, then prime minister-designate Cho Jung-tai announced that Chiu will be the new minister of Health and Welfare in the new cabinet.
# Life Paint

Life Paint is the trade name of a highly-reflective spray paint developed by Volvo to increase the visibility of cyclists during trips after dark. It was developed in collaboration with Swedish reflective spray manufacturer 'Albedo 100', who previously marketed a similar paint for use on the coats of pets and horses. The paint lasts for about one week after use, but is easily washed off without damaging the surface to which it was applied. Although initially developed for the use of cyclists, it could also protect pedestrians.
It has been criticized by cycling advocates as victim blaming by shifting the onus from responsible driving or safer car design to vulnerable road-users who are injured by motor vehicles, even drawing a petition to retrofit Volvo vehicles with 'Life Paint'.
# The Siege (1956 film)

The Siege (Opsada) is a Croatian film directed by Branko Marjanović. It was released in 1956.
# Freedom Party (Iceland)

The Freedom Party (Icelandic: Frelsisflokkurinn) was a right-wing populist political party in Iceland. The party was founded in June 2017 and participated in the 2018 city council elections in Reykjavík where it received 147 votes, or about 0.24% of total votes. Since 2023, the party became inactive, and a few posts were made on the party's Facebook page in support of the Centre Party.
# Nepal Skating and Skateboarding Association

The Nepal Skating and Skateboarding Association (NSSA) is the national governing body for roller sports, particularly roller skating and skateboarding, in Nepal. NSSA is registered under NSC and registration number is (NSC-150). NSSA regularly organize and sanction different national level competition and tournaments. Through these tournaments NSSA provide platform to players participate in international level. NSSA manages all categories of this sport figure, speed & short track.

## Affiliated Association

* Bagmati Province Skating and Skateboarding Association
* Gandaki Province Skating and Skateboarding Association
# Charlie Beech

Charlie Beech (born 21 July 1987 in Stevenage, England) is a rugby union player for Coventry R.F.C. in the RFU Championship. He plays as a prop.
Beech represented England at the U19 World Championship in 2006. Beech also represented the England under-20 team in the 2007 Six Nations.
Beech joined the academy of Northampton Saints in 2003, he made one appearance for their senior side, against Rugby Viadana in the European Challenge Cup. After Saints were relegated in the 2006–07 season, Beech signed for London Wasps.
Beech made his competitive debut for Wasps against London Irish, in their first win of the 2007–08 Guinness Premiership. He would have to wait another 13 months before his next appearance, when he scored a match winning try against the Newcastle Falcons. In April 2009, Beech signed a contract.
It was announced on 8 March 2011 that Beech had signed for Bath on a three-year deal. In October 2013, Beech signed for Yorkshire Carnegie on an indefinite loan from the rest of the 2013–14 season. However, he signed a permanent deal with Yorkshire Carnegie, effectively leaving Bath.
On 8 April 2018, Beech left Leeds to join Championship rivals Coventry
# Captain Napin

Captain Napin (died 1718, first name unknown, last name occasionally Napping) was a pirate active in the Caribbean and off the American east coast. He is best known for sailing alongside Benjamin Hornigold.

## History

Little is recorded of Napin's early life. In April 1717 he was sailing alongside Benjamin Hornigold. They plundered several vessels in quick succession off Puerto Bello and Jamaica until they were chased away by HMS Winchelsea near Cuba. Napin parted from Hornigold by the summer of 1717, though he continued to sail with Hornigold sporadically until that October.
Nathaniel Brooker of the snow Restoration reported being attacked in August 1717 by Napin and Thomas Nichols while sailing from London to Boston (Hornigold was not present). The pirates released Restoration after looting it of everything from provisions and trade goods to kettles and frying pans. Brooker described Napin's jolly roger flag: he "had in his flag a death’s head and an hourglass." Napin and his 12-gun, 100-man sloop were also behind a solo attack on a pink named Adventure in September, and a ship's tender off of Trinidad in October.
Captain Vincent Pearse of HMS Phoenix sailed to Nassau in early 1718 to bring news of King George I's general pardon for pirates for those who surrendered by September. Nichols and Hornigold accepted the pardon; Pearse wrote that "there is an other Sloop out Commanded by Capt. Napping they expect in Dayly" but Napin never arrived to accept the pardon. There are few records of Napin's activities after he was reported as sailing between Brazil and the African coast in March 1718.
In late 1718 a group of sailors led by Thomas Bowling were captured by Spanish guarda costa privateers off Cuba. They were eventually released but were forced to leave one man behind. A later report arrived stating that "It seems one of them [the Spanish ships] comanded by Diego Philippe carried out Napping who was taken with Capt. Bowling and put him ashore on St. Andrews Island, sending him off with his gunner and two negroes arm'd, and one of the three then shot Napping, the fire of the pistol being plainly seen by many of the sloop's company." Governor Woodes Rogers confirmed his death, noting that "Napping was murder'd, for his skull is brought hither and his bones buri'd by the Englishmen yt.[that] was left on Andrew's Island."
# Jimmy Gardner (actor)

Edward Charles James Gardner, DFM (24 August 1924 – 3 May 2010) was an English actor.
During World War II, Gardner served in the Royal Air Force as an air gunner with No. 10 Squadron. He completed 30 sorties as a Halifax rear gunner and was awarded the Distinguished Flying Medal.
His first film appearance was in The Curse of the Mummy's Tomb released during 1964. Thereafter he appeared in over 30 films and also made extensive TV and theatre appearances. Some of his best known Shakespearean roles such as Adam in As You Like It, and Gravedigger in Hamlet were performed under the direction of Terry Hands.
He played Knight Bus driver Ernie Prang in Harry Potter and the Prisoner of Azkaban, the third film in the Harry Potter film series.

## Filmography

* Doctor Who : Marco Polo (1964) .... Chenchu
* The Curse of the Mummy's Tomb (1964) .... Fred's Mate
* He Who Rides a Tiger (1965) .... Waiter
* The Murder Game (1965) .... Arthur Gillett
* Arabesque (1966) .... Hemsley (uncredited)
* The Committee (1968) .... Boss
* Take a Girl Like You (1970) .... Voter
* Say Hello to Yesterday (1971) .... Balloon Seller (uncredited)
* 10 Rillington Place (1971) .... Mr Lynch
* Up the Chastity Belt (1971) .... Little Man
* Frenzy (1972) .... Hotel Porter
* Ooh... You Are Awful (1972) .... Waterloo Porter (uncredited)
* Take Me High (1973) .... Hulbert
* 11 Harrowhouse (1974) .... Man in Snack Bar (uncredited)
* Percy's Progress (1974) .... Clerk of Court (uncredited)
* Slade in Flame (1975) .... Charlie's Dad
* Short Ends (1976) .... Alchemist
* Doctor Who : Underworld (1978) .... Idmon
* Tess (1979) .... Pedlar
* The Company of Wolves (1984) .... Ancient
* Mountains of the Moon (1990) .... Jarvis
* Robin Hood: Prince of Thieves (1991) .... Farmer
* Thin Ice (1995) .... Old Man with gun
* Gunslinger's Revenge (Italian title: Il mio West) (1998) .... Sam Comet
* Harry Potter and the Prisoner of Azkaban (2004) .... Ernie the Bus Driver
* Finding Neverland (2004) .... Mr. Snow
* Deuce Bigalow: European Gigolo (2005) .... Kaiser (final film role)
# Elk Pass (Canada)

Elk Pass (el. 1,905 m or 6,250 ft) is a high mountain pass in the Canadian Rockies, traversing the continental divide. It connects the Elk Valley in the province of British Columbia with the Kananaskis Valley in Alberta.
The pass is unusual by its 4 km (2.5 mi) width, as the two valleys were created from a single glaciated trench. The 1916 Alberta/British Columbia Provincial Boundary Surveyors subdivided it into two routes labeled as "West Passage" and "East Passage." These would later be gazetteered as West Elk Pass and East Elk Pass.
Elk Pass is inaccessible to conventional road traffic. On the Albertan side it reaches into Peter Lougheed Provincial Park, while on the British Columbian side it is slightly east of Elk Lakes Provincial Park.
The Trans Canada Trail has hoped to designate preexisting hiking trails through the Elk Pass as its continental divide-crossing section, but has come into conflict with coal mines in the Upper Elk Valley over the impacts such a routing would have on their ability to expand their mine sites. In the past, residents of Elkford, British Columbia had proposed extending British Columbia Highway 43 over the pass and into Alberta, creating a new all-weather route from B.C. to Calgary, but in light of enhanced environmental protection on the Albertan side, the project is no longer considered likely.
# Alexandra the Maccabee

Alexandra the Maccabee (died ca. 28 BC), part of the Hasmonean dynasty, was an influential politician in Judea. She is most famous for her intense political manoeuvrings and attempted coup against her son-in-law, Herod the Great.
She was the daughter of Hyrcanus II (died 30 BC), and granddaughter of Alexander Jannaeus. She married her cousin Alexander of Judaea (died 48 BC), who was the son of Aristobulus II. Their grandfather was Alexander Jannaeus, the second eldest son of John Hyrcanus. Their daughter was the Hasmonean Mariamne and son was Aristobulus III.
Alexandra opposed her son-in-law Herod, and when he became sick with grief after having Mariamne executed, Alexandra tried to seize power, but was unsuccessful and was herself executed.
# Keavy, Kentucky

Keavy is an unincorporated community in Laurel County, Kentucky, in the United States. Keavy has its own post office with the zip code 40737.

## History

Keavy was named after a shoe brand.

## Geography

Keavy is located at the intersection of Kentucky Routes 312 and 363 in Laurel County.

## Notable person

Keavy is the birthplace of former Auburn University, and current Las Vegas Raiders quarterback Jarrett Stidham.

## Media

* WVCT, Southern gospel Christian radio station in Keavy.
# Ben Botica

Ben Botica (born 7 October 1989, Takapuna) is a New Zealand rugby union player. A fly-half or centre, he plays for French club Soyaux Angoulême XV Charente.
The son of the New Zealand international Frano Botica, he played rugby at school and was selected to play for the New Zealand Schoolboys team. In 2008, he spent a year in France where he played with the Espoirs (Academy) team of Biarritz Olympique.
He then returned to New Zealand where he joined North Harbour. He played his first professional match in August 2009 against Southland in the Air New Zealand Cup. In 2011, he narrowly missed out on selection for the Auckland Blues franchise and the chance to play in Super Rugby. He returned to France where he played the 2011-2012 Pro D2 season with CA Périgueux.
Late in the season, it was announced that he had signed a two-year contract with Harlequins although he actually signed in October 2011. As a British passport holder, he did not count as a foreign player. In his initial season with Harlequins, he was the top points scorer (with 78) in the LV Cup.
In his final game at Harlequins, the 2016 European Challenge Cup Final, Botica came on as a replacement to face the club he was about to join. With time nearly up and Quins trailing by 7 points he kicked the ball to Montpellier who put it into touch to end the game. Most had expected him to keep the ball live and mount one final attack to attempt to level the scores and take it to extra time. It was Head Coach Conor O'Shea's last game for the club.
Botica joined Montpellier in 2016 and moved to Oyonnax in 2017.
On 16 November 2020, Botica would sign for French rivals Castres on a two-year deal from the 2021–22 season.
# The Very Best of The Jacksons

The Very Best of The Jacksons (released in Japan under The Very Best of The Jackson 5/The Jacksons: Anthology 1969–1987) is a greatest hits compilation by the Jacksons during their years at Motown as the Jackson 5 to their last single released by Epic Records in 1989. The compilation is a joint release with Universal Music Group, Motown's current parent, and was distributed on July 5, 2004, in the United Kingdom and December 22, 2004, in Japan by Sony Music. Featured are most of the hit singles the group, including their first hit in 1969 "I Want You Back" as well as popular hits such as "ABC", "This Place Hotel" and "Shake Your Body (Down to the Ground)". The compilation also includes songs Michael Jackson released during his solo career at Motown as well as a live recording of his first smash hit at Epic, "Don't Stop 'Til You Get Enough".
The cover art is similar to Number Ones, a similar album consisting of lead singer Michael Jackson's solo career from 1979 to 2003.

## Certifications

Certifications for The Very Best of The Jacksons :
| Region | Certification | Certified units/sales |
| United Kingdom (BPI) | Gold | 100,000$^^$ |
| $^^$ Shipments figures based on certification alone. |||
# JS Yūbetsu (DE-228)

JS Yūbetsu (DE-228) was a Yūbari-class destroyer escort of the Japanese Maritime Self-Defense Force.

## Development and design

The Maritime Self-Defense Force has further developed the Coast Guard (PCE) plan, which was considered in the Third Defense Build-up Plan as an alternative to the conventional submarine chaser (PC), and JS Ishikari in the post-fourth defense plan in 1977.
However, the 52DE was too small and lacked room. The lack of ability to act in stormy weather due to the ship's shape was also a problem. The original plan was to build more ships of the same type as a replacement for the retired submarine chaser, but before the commissioning of the ship, the ships built in 1979 were homomorphic ships with a slightly expanded ship type.
From the above background, the basic design is an advanced version of 52DE. The basic plan number is E111. The central hull form has been followed and looks very similar, but the standard displacement has been increased by about 200 tons, the total length has been extended by 6 meters, and the overall width and depth have also increased slightly. Along with this, the floor area of the battle area including CIC and the living area has increased, and the warehouse has been expanded to improve the living and living environment. The fuel tank was also enlarged and the fuel load increased by about 35 percent, which led to an extension of the cruising range. The engine had the same configuration as the 52DE, and was a CODOG system with Mitsubishi Heavy Industries 6DRV35 / 44 diesel engine and Kawasaki-Rolls-Royce Olympus TM3B gas turbine engine.

## Construction and career

The destroyer escort was laid down on 14 January 1982 and launched on 25 January 1983 at Hitachi Zosen Corporation Shipyard in Maizuru. Yūbetsu commissioned on 14 February 1984.
The vessel was engaged in disaster dispatch activities due to the Hokkaido Nansei-oki Earthquake that occurred on 12 July 1993.
On 24 March 1997, the 35th escort corps was renamed to the 27th escort corps due to the revision of the corps number. On 3 April 2006, the 27th Escort Corps was abolished and transferred to the 25th Escort Corps of the Ominato District Force. On 26 March 2008, the 25th escort corps was renamed to the 15th escort corps due to a major reorganization of the Self-Defense Fleet, and was reorganized under the escort fleet. Yūbetsu was decommissioned on 25 June 2010 and sent to scrap few years later.

## Gallery

* JS Yūbetsu on 30 July 2004.
* JS Yūbetsu on 30 July 2004.
* JS Yūbetsu fires her 375 mm Bofors on 29 October 2007.
* JS Yūbetsu and JS Yūbari on 6 September 2011.
# John Brake (rugby union, born 1988)

John Brake (born 22 April 1988 in London, England) was a professional rugby union player for England Sevens in the IRB Sevens World Series. Brake's position of choice in the 15-a-side code is Scrum-half.

## Club career

After joining the academy side at Northampton Saints in 2006, Brake went on to make his National League debut for the senior side against Bedford Blues in the RFU Championship during the 2007–2008 campaign. He went on to make a further seven appearances throughout the season and scored a try against Launceston RUFC. At the end of his debut senior season Northampton achieved promotion back to the Guinness Premiership. Brake went onto represent Northampton Saint for 4 seasons. .In August 2010 Brake left Northampton Saints and signed for England Sevens and Birmingham and Solihull on a dual contract. He left the Bees at the end of the 2010–2011 season to pursue a central contract with the England Sevens Squad.
In 2021, Brake made the decision to convert codes and play Australian Rules Football. He made his debut for the London Swans and won the 2021 premiership in an undefeated side with a close to best on ground performance.

## International career

Brake represented England as a schoolboy at Millfield at under-16 and under-18 levels. After leaving and joining Northampton he progressed to the under-20 side and made his debut for the England Sevens team in San Diego in 2007.
Brake went on to represent England Sevens for 6 seasons, playing in 41 World Series Tournaments, 2 Commonwealth Games in Delhi 2010 and Glasgow 2014, 1 Sevens World Cup in Moscow 2013 and 10 European Tournaments
Brake captained the winning England Sevens team in the 2012 European Sevens Grand Prix.