# 2018 Internazionali di Tennis Città di Perugia – Singles

Laslo Đere was the defending champion but chose not to defend his title.
Ulises Blanch won the title after defeating Gianluigi Quinzi 7–5, 6–2 in the final.

## Seeds

* Gerald Melzer (first round)
* Pablo Andújar (first round)
* Blaž Kavčič (withdrew)
* Enrique López Pérez (first round)
* Nikola Milojević (second round, retired)
* Matteo Donati (second round)
* Attila Balázs (semifinals)
* Carlos Taberner (second round)
* Kenny de Schepper (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| | Salvatore Caruso | 2 | 0 | | | | |
| | Gianluigi Quinzi | 6 | 6 | | | | |
| | Gianluigi Quinzi | 6 | 6 | | Gianluigi Quinzi | 5 | 2 |
| | | | | LL | Ulises Blanch | 7 | 6 |
| LL | Ulises Blanch | 6 | 6 | LL | Ulises Blanch | 7 | 6 |
| 7 | Attila Balázs | 4 | 2 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals |
| 1 | G Melzer | 1 | 6 | 6$^4$ | | | | | | | | | | | | |
| | T Brkić | 6 | 1 | 7$^7$ | | T Brkić | 1 | 2 | | | | | | | | |
| | F Argüello | 6 | 4 | 2 | | A Giannessi | 6 | 6 | | | | | | | | |
| | A Giannessi | 3 | 6 | 6 | | | | | | A Giannessi | 6 | 4 | 4 | | | |
| Q | A Pavić | 4 | 7$^{10}$ | 3 | | | | | | S Caruso | 4 | 6 | 6 | | | |
| | S Caruso | 6 | 6$^8$ | 6 | | S Caruso | 6 | 2 | | | | | | | | |
| | DE Galán | 6$^1$ | 2 | | 5 | N Milojević | 4 | 1$^r$ | | | | | | | | |
| 5 | N Milojević | 7$^7$ | 6 | | | | | | | | | | | S Caruso | 2 | 0 |
| 9 | K de Schepper | 6 | 6 | | | | | | | | | | | G Quinzi | 6 | 6 |
| | N Serdarušić | 4 | 4 | | 9 | K de Schepper | 4 | 6 | 1 | | | | | | | |
| | D Gimeno Traver | 7 | 6 | | | D Gimeno Traver | 6 | 3 | 6 | | | | | | | |
| | R Cid Subervi | 5 | 3 | | | | | | | D Gimeno Traver | 1 | 2 | | | | |
| | R Ojeda Lara | 4 | 5 | | | | | | | G Quinzi | 6 | 6 | | | | |
| | G Quinzi | 6 | 7 | | | G Quinzi | 6 | 6 | | | | | | | | |
| Q | G Escobar | 6$^2$ | 4 | | 6 | M Donati | 4 | 4 | | | | | | | | |
| 6 | M Donati | 7$^7$ | 6 | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | C Taberner | 6 | 6 | | | | | | | | | | | | | | |
| WC | J Berrettini | 2 | 2 | | 8 | C Taberner | 5 | 4 | | | | | | | | | |
| WC | N Almagro | 4 | 5 | | LL | U Blanch | 7 | 6 | | | | | | | | | |
| LL | U Blanch | 6 | 7 | | | | | | | LL | U Blanch | 6 | 6 | | | | |
| Q | P Toledo Bagué | 7$^7$ | 3 | 6 | | | | | | | B Zapata Miralles | 4 | 4 | | | | |
| WC | E Dalla Valle | 6$^5$ | 6 | 4 | Q | P Toledo Bagué | 2 | 0 | | | | | | | | | |
| | B Zapata Miralles | 7$^7$ | 3 | 6 | | B Zapata Miralles | 6 | 6 | | | | | | | | | |
| 4 | E López Pérez | 6$^2$ | 6 | 4 | | | | | | | | | | LL | U Blanch | 6 | 6 |
| 7 | A Balázs | 6 | 3 | | | | | | | | | | | 7 | A Balázs | 4 | 2 |
| | G Barrère | 4 | 0$^r$ | | 7 | A Balázs | 6 | 6 | | | | | | | | | |
| Q | C Rodríguez | 2 | 4 | | | B Rola | 1 | 3 | | | | | | | | | |
| | B Rola | 6 | 6 | | | | | | | 7 | A Balázs | 6 | 7$^7$ | | | | |
| | G Sakharov | 4 | 6 | 6 | | | | | | | M Trungelliti | 2 | 6$^3$ | | | | |
| | J Domingues | 6 | 3 | 3 | | G Sakharov | 6 | 5 | 4 | | | | | | | | |
| | M Trungelliti | 6 | 6 | | | M Trungelliti | 4 | 7 | 6 | | | | | | | | |
| 2/WC | P Andújar | 3 | 2 | | | | | | | | | | | | | | |