OpenLLM-France/wikimedia huggingface dataset:
# Tupua Tigafua

Tupua Tigafua is a Samoan choreographer and dancer based in New Zealand. Tigafua was a recipient of the Creative New Zealand Arts Pasifika Award for Emerging Artist in 2017. In 2021, the Wellington Theatre Awards presented him with the Excellence Award for Choreography and Movement for original work Ciggy Butts in the Sand.

## Early life

Born in Mount Wellington, Auckland. Tigafua is of Samoan descent with links to Safa’ato’a, Lefaga and Faleū, Manono. The youngest of five siblings, he was a practitioner of Samoan and Tongan dance. Tigafua's first attempt to transition to contemporary dance resulted in not completing studies at Unitec.

## Career

At 20 years of age, Tigafua was approached to dance with Black Grace, which he did for three years. Soon he was to follow it up with a stint in Lemi Ponifasio's Mau. The company's work was based primarily in Berlin centred around stories of immigrants who lived in the city. In 2012 he joined The New Zealand Dance Company and four years later, Tigafua made the decision to continue as an independent choreographer and dancer.
   “It’s important to tell, or to add to our conversation but not to repeat the same thing or say it louder. From my perspective as New Zealand-born I got to travel a lot so you learn to be more curious about things around you — like the garage drink-up but I’m adding my perspective.” (Tigafua)

## Performances, Choreography and Works

2012-2014 Language of Living, The New Zealand Dance Company, New Zealand
2013-2015 Rotunda, The New Zealand Dance Company, Australia, Netherlands, New Zealand
2015-2017 Double Derelicts, White Face Crew, Kia Mau Festival, Wellington, Matariki on the Move programme, Auckland, Centrepoint Theatre, Palmerston North, Hawkes Bay Arts Festival, Hamilton Gardens Festival, New Zealand
2016 Lumina, The New Zealand Dance Company, Germany, Holland, New Zealand
2016 Plan B, SIVA, Niu Sila, Auckland Tempo Dance Festival, Q Theatre, Auckland, New Zealand
2016 Ghostdance, Brouhaha, The New Zealand Dance Company, White Night, Auckland Arts Festival
2018 Home Sweet Home, Search Engine, Footnote New Zealand Dance, New Zealand
2019 Shel We? Kia Mau Festival, Wellington, New Zealand
2019 Alofagia:Le Opera, TAPA, Auckland Council, Nathan Homestead, Manurewa Local Board, Auckland, New Zealand
2020 Ngā Wai, Rangatira, Atamira Dance Company, The New Zealand Dance Company, Q Theatre, Auckland, New Zealand
2021 Songs of Protest, Toi Whakaari, Wellington, New Zealand
2021 Shel We? Pacific Dance Festival, ASB Waterfront Theatre, Auckland New Zealand
2021 Ciggy Butts in the Sand, Te Papa Soundings Theatre, Wellington, New Zealand

## Awards

2021 Shel We? Excellence Award for Choreography and Movement, The Wellington Theatre Awards
2017 Emerging Artist Award, Creative New Zealand Pasifika Arts
# Benigno Aquino

Benigno Aquino may refer to:
* Benigno Aquino Sr. (1894–1947), Filipino politician and speaker of the House of Representatives from 1943 to 1944
* Benigno Aquino Jr. (1932–1983), Filipino politician, son of Benigno Sr., former senator, and former governor of Tarlac
* Benigno Aquino III (1960–2021), Filipino politician, son of Benigno Jr., and 15th president of the Philippines
* Paolo Benigno Aquino IV (born 1977), Filipino politician, cousin of Benigno III
# Punyalan Agarbattis

Punyalan Agarbattis (transl. Saint Incense Sticks) is a 2013 Indian Malayalam-language satirical comedy film written, co-produced, and directed by Ranjith Sankar, starring Jayasurya, Nyla Usha, Aju Varghese, Rachana Narayanankutty, Innocent, and Sreejith Ravi. It follows the tale of the young entrepreneur, Joy Thakkolkaran (Jayasurya), and his business venture "Punyalan Agarbattis" in the city of Thrissur. The film is produced by Jayasurya and Ranjith Sankar under the banner of Dreams N Beyond and features music composed by Bijibal. It was a commercial success at the box office. A sequel of the film titled 'Punyalan Private Limited' was made in 2017, and it had many of the members of the original cast.

## Plot

The movie follows the inspiring tale of an entrepreneur, Joy Thakolkaaran, who owns a firm named 'Punyalan Agarbathis'. The firm is involved in the production of incense sticks from elephant dung. The first half moves around how it becomes nearly impossible for him to acquire the necessary raw material (elephant dung), and when he finally does acquire it, the devil follows him in the form of a hartal. Struggling between the deadline given by the court and the unexpected hartal, he decides to smuggle the raw material on the day of the hartal. When the RIP followers get wind of this, they attack Joy and destroy his godown and means of transportation. The rest of the movie revolves around how Joy is pressured by various problems around him and how help comes from the unexpected. The party uses different methods to mentally depreciate Joy. However, he overcomes them with his optimistic attitude and his friends and family. At the end of the movie, the tagline reads "You can conquer the whole world if you are ready to believe in yourself"

## Cast

* Jayasurya as Joy Thakkolkaran
* Aju Varghese as Greenu Sharma
* Nyla Usha as Anu Joy
* Sreejith Ravi as Abhayakumar (Thuthuru)
* Innocent as John Thakkolkaran, Joy's grandfather
* Rachana Narayanankutty as Advocate Remya
* T. G. Ravi as Achuthan Maash, a social worker
* Idavela Babu as K C Mathews
* Mala Aravindan as Ayyappan
* Sunil Sukhada as Magistrate
* Shivaji Guruvayoor as Advocate Hassan Marakkar
* Gokulan as Jimbruttan
* Lishoy as Joy's uncle
* Jayaraj Warrier as Kaattalan Jose
* Sabumon Abdusamad as Idivettu Sabu
* Thesni Khan as Gracy
* Ponnamma Babu as Usha
* Irshad as Amal
* Vinod Kovoor as Pappan Kottaparambu
* Sudheer Karamana as Kollur Jayaprakash
* Sunil Babu as Mahout Eldho

## Production

Jayasurya was selected to play the lead and Nyla Usha his wife. The popular senior actor Innocent was cast to play the grandfather of hero.
The filming began at Thrissur on 17 August 2013.

## Release

The film was released on 29 December 2013.
It was both a commercial and critical success. The film collected ₹7 crore from Kerala box office.

## Soundtrack

Bijibal composed the background score and songs. The film marked the debut of Jayasurya as a singer in films. The lyrics are written by Santhosh Varma.
| Track | Song Title | Singer(s) |
| 1 | "Poorangalude Pooram" | P. Jayachandran |
| 2 | "Aashichavan" | Jayasurya |
| 3 | "Esho Parayunna" | Arun Alat |
# Piece of My Heart (Intermission song)

"Piece of My Heart" is a song by German Eurodance project Intermission. Written by Nosie Katzmann and Tony Dawson-Harrison from Captain Hollywood Project, it was released in August 1993 by Blow Up and Intercord as the second single from the album by same name (1994). It features vocals by American singer Valerie Scott and uses the interpolated melody of the 1983 song "Send Me An Angel" by Australian band Real Life. The single was a top-10 hit in Austria, Germany and Spain. It spent 12 weeks on the German Singles Chart. In 2003, trance music duo Grey & Frost updated "Piece of My Heart" into a modern hard trance sound.

## Chart performance

"Piece of My Heart" was a major hit in several European countries, entering the top-10 in Austria (9), Germany (8), and Spain (7). It spent two weeks as number eight and 12 weeks within the German Singles Chart. Additionally, it reached numbers 40 and 42 in Switzerland and Belgium. The song debuted on the Eurochart Hot 100 at number 78 on 30 October 1993, after charting in Austria and Germany. It peaked at number 33 in January 1994. Outside Europe, "Piece of My Heart" was a top-20 hit in Israel, peaking at number eleven in September 1993, as well as reaching number 188 in Australia.

## Track listing

* CD single, France (1993)
* "Piece of My Heart" (single mix) – 4:05
* "Piece of My Heart" (piece mix)
* CD single (Remixes), Europe (1993)
* "Piece of My Heart" (single mix) – 4:05
* "Piece of My Heart" (heart mix) – 6:38
* CD maxi, Germany (1993)
* "Piece of My Heart" (piece mix) – 6:46
* "Piece of My Heart" (heart mix) – 6:38
* "Piece of My Heart" (single mix) – 4:05
* CD maxi (Remixes), Germany (1993)
* "Piece of My Heart" (T.K. remix) – 5:46
* "Piece of My Heart" (The Legacy Of Sound remix) – 6:34
* "Piece of My Heart" (Underground remix) – 8:28
# Nova Institution for Women

Nova Institution for Women (French: Établissement Nova pour femmes) is a Canadian federal prison for women in Truro, Nova Scotia. The facility, which handles different levels of offenders, can accommodate up to 70 inmates. Nova Institution opened in 1995. The maximum security unit opened in 2002 or 2003.
Main programs at the institution include:
* Living skills
* Sex offender programs
* Substance abuse treatment
The Correctional Service of Canada (CSC) is the federal government agency responsible for administering sentences of a term of two years or more.

## Ashley Smith

Ashley Smith, a prisoner who later died after an apparent suicide attempt, was held at several CSC institutions including Nova Institution.
# Eddy Hellebuyck

Eddy Hellebuyck (born 22 January 1961) is a Belgian-born American long-distance runner. He competed in the men's marathon at the 1996 Summer Olympics, representing Belgium and finishing in 67th place. By 2000, he had become a U.S. citizen and competed in the U.S. Olympic Trials that year, but did not make the team. His P.R. is 2:11.50 set in 1994 at the Antwerp Marathon. He also won the Cleveland Marathon in 1989, the Lake Biwa Marathon in Japan in 1990, and then the Columbus Marathon in 1994. His last win at this distance was in the Twin Cities Marathon in 2:12.47, a new US master's record, in 2003.
In 2004, he tested positive for recombinant human Erythropoietin (rhEPO) and was suspended from competition for two years. Hellebuyck's U.S. master's record was accordingly rescinded and his victory in the Twin Cities was nullified through this performance enhancing drug disqualification.
# Alexander Ross (civil servant)

Alexander Ross (1800–1889) was a British civil servant in India.

## Life

In November 1808 he was appointed judge and magistrate of the District of Allyghur.
He was Patron of Calcutta School Book Society form its institution on 4 July 1817.
He was temporarily appointed as a Member of the council of the Governor General on 8 January 1833 on which he was confirmed on 15 October 1833.
On 1 December 1835 he was posted as Governor of the Presidency of Agra where he served for over six months until 1 June 1836. On 27 April 1836 he was re-appointed as a Member of the council of the Governor General from which he resigned on 15 October 1838. On 20 October 1837 he was appointed as President of the Council of India, and Deputy Governor of the Presidency of Fort William and of the town of Calcutta (now Kolkata. He was 1st Ordinary Member of the Supreme Council of Government of India in 1838. He was Deputy Governor in the Government of Bengal in 1838.
He was appointed Deputy Governor of the garrison at Fort William in 1838.
# Pterodontia notomaculata

Pterodontia notomaculata is a species of small-headed flies (insects in the family Acroceridae).
# Elisabeth Garcia

Elisabeth Garcia (born 3 January 1975) is a Norwegian sport wrestler.
She won a bronze medal at the 1991 World Wrestling Championships in Tokyo.
She represented the club Lørenskog BK.
# Low Down

Low Down is a 2014 American biopic directed by Jeff Preiss and based on the memoirs written by Amy-Jo Albany (portrayed by Elle Fanning) about her father, famed jazz pianist Joe Albany (portrayed by John Hawkes), and his struggles with drug addiction.
The film was executive produced by Anthony Kiedis and Flea (who also co-stars in the film) of the Red Hot Chili Peppers.
The film premiered in competition at 2014 Sundance Film Festival on January 19, 2014. It won the "Cinematography Award: U.S. Dramatic" at the festival.

## Plot summary

Joe Albany was an accomplished jazz pianist during the 1960s through the 1980s, performing with the likes of Charlie Parker, Miles Davis, and Charles Mingus before his descent into heroin addiction. The film tells the story of Albany's life from the perspective of his daughter, Amy-Jo Albany, a frequent witness to his drug use (and related legal trouble) as well as his passion for music.

## Cast

* John Hawkes as Joe Albany
* Elle Fanning as Amy-Jo Albany
* Lena Headey as Sheila Albany
* Glenn Close as Gram
* Flea as Hobbs
* Caleb Landry Jones as Cole
* Taryn Manning as Colleen
* Peter Dinklage as Alain
* Billy Drago as Lew
* Burn Gorman as Parole Officer Wiggenhern
* Tim Daly as Dalton
* Linda Wang as Chinese Woman
* Rain Phoenix as Kitty
* Wiley Pickett as Gentleman Cowboy

## Production

Actor Mark Ruffalo was originally cast as Joe Albany in 2011 but was forced to back out due to scheduling issues and production being delayed.

## Release

The film made its debut at the Sundance Film Festival on January 19, 2014, winning an award for Best Cinematography. It also won Best Film at the New Hampshire Film Festival in 2014. The first official trailer was released on September 18, 2014. The film opened to a limited release on October 24, 2014 in New York City and October 31, 2014 in Los Angeles.

## Reception

Low Down was met with mixed reviews. Review aggregator website Rotten Tomatoes sampled 50 critics' reviews, 25 positive and 25 negative, bringing the score to 50%, averaging 5.7/10. The film's consensus reads: "Rich in mood and on-screen talent but lacking in narrative depth, Low Down tells an oft-told tale with a troubling dearth of imagination." Metacritic, another review aggregator, gives the film 58 out of 100 based on reviews from 21 critics (six of them positive, thirteen mixed, and two negative), with its general agreement being "mixed or average reviews".
Matt Zoller Seitz, writing for RogerEbert.com, gave the film three-and-a-half stars out of four, calling it "a very good jazz movie and a very good heroin movie," while Rex Reed described Elle Fanning's performance as "heartbreaking". George Varga of the San Diego Union-Tribune deemed Low Down "a grimly gripping movie" but was less effusive than Seitz, giving it two-and-a-half stars.
David Edelstein, in Vulture, praised the performances by Hawkes, Fanning, and much of the supporting cast, but felt that the film was "not as entertaining as" the book on which it was based: "The weakness of Low Down is that it misses the wry tone and scruffy, eccentrically funny parts of [Amy-Jo] Albany’s memoir."
# Raita Ryū

Raita Ryu (竜 雷太, Ryū Raita, born January 21, 1940 in Osaka as Tatsuo Hasegawa (長谷川 龍男, Hasegawa Tatsuo)) is a Japanese actor. He is well known for his role as Gorisan (Detective Ishizuka) in Taiyō ni Hoero!. He has a son Yōhei Hasegawa (長谷川 陽平, Hasegawa Yōhei), who is a musician and guitarist.
Once, he belonged to Toshiro Mifune's production company.

## Selected filmography
### Films

* Moero! Seishun (1968) - Raita Ejima
* The Bullet Train (1975) - Kikuchi
* Stage-Struck Tora-san (1978) - Detective Hashikawa
* G.I. Samurai (1979) - Haruhisa Kimura
* Station (1981)
* Sukkari... sono ki de! (1981) - Detective
* Kizudarake no Kunshō (1986) - Toshima
* Tokyo Blackout (1987) - Horie
* Kanbakku (1990)
* Isan Sōzoku (1990) - Motoharu Fujishima
* Rainbow Kids (1991) - Sakuma
* Tsuribaka Nisshi (1994-1998) - Chief of Personnel Haraguchi
* Oishinbo (1996)
* Hana no oedo no Tsuribaka Nisshi (1998)
* Keizoku: The Movie (2000) - Kōtarō Nonomura
* Happily Ever After (2007)
* 20th Century Boys 1: Beginning of the End (2008) - Chō-san
* First Love: A Memory in Summer (2009)
* Hanjiro (2010)
* Homecoming (2011) - Tadashi Ohshima
* SPEC: Ten (2012) - Kotaro Nonomura
* SPEC: Close (2013) - Nonomura Kotaro
* A Banana? At This Time of Night? (2018) - Kiyoshi Kano
* We Make Antiques! Kyoto Rendezvous (2019) - Manzo Okuno
* Hope (2020)
* Food Luck (2020)
* What Happened to Our Nest Egg!? (2021)

### Television

* Taiyō ni Hoero! (1972-1982) - Ishizuka "Gori-san" Makoto
* Tokugawa Ieyasu (1983) - Tenkai
* Sanada Taiheiki (1985-1986) - Katō Kiyomasa
* Dokuganryū Masamune (1987) - Date Sanemoto
* Abare Hasshū Goyō Tabi (1991-1994)
* Hoshi no Kinka (1996) - Seiichirō Nagai
* Unsolved Cases (1999) - Kōtarō Nonomura
* Aoi (2000) - Gamō Satoie
* Kokoro (2003) - Ikkoku Nakajima
* The Man Who Can't Get Married (2006)
* Fūrin Kazan (2007) - Amari Torayasu
* Teppan (2010-2011) - Den Hasegawa
* Gunshi Kanbei (2015) - Kuroda Shigetaka
* Segodon (2018) - Zusho Hirosato
* Ōoku: The Inner Chambers (2023) - Keishō-in
# Dhola, Gujarat

Dhola is a census town and former petty Rajput princely state in Bhavnagar district, in the state of Gujarat, western India.

## History

Dhola was one of many non-salute states in Gohilwad prant on Saurashtra peninsula, comprising only the village. Under the British raj, the colonial Eastern Kathiawar Agency was in charge of it.
In 1901 it comprised only the village, with a population of 261, yielding 1,800 Rupees state revenue (1903-4, all from land), paying 384 Rupees tribute to the Gaikwar Baroda State and Junagadh State.

## Geography

Dhola is located at 21°53′N 71°47′E﻿ / ﻿21.88°N 71.78°E﻿ / 21.88; 71.78. It has an average elevation of 56 metres (183 feet).
Dhola is a Railway Junction in Bhavnagar State Railway.

## Demographics

As of 2001 India census, Dhola had a population of 8049.
* Males constitute 52% of the population and females 48%.
* Dhola has an average literacy rate of 67%, higher than the national average of 59.5%: male literacy is 75% and, female literacy is 58%.
* In Dhola, 14% of the population is under 6 years of age.
# Parachute (The Pretty Things album)

Professional ratings :
| Review scores ||
| Source | Rating |
| Allmusic | |
| Record Collector | |
Parachute is the fifth studio album by the English rock band Pretty Things, released in 1970. It is their first album without guitarist Dick Taylor.
Reviews at the time of release were very positive, with Billboard calling it "another top-flight album" for the band. In 1975, Rolling Stone critic Steve Turner wrote that it had been "a Rolling Stone 'album of the year'," though in fact Parachute did not place among the magazine's Albums of the Year for 1970 or 1971, and indeed was not mentioned in Rolling Stone until Stephen Holden called it an "obscure underground classic" in his review of Freeway Madness.
The band's lineup at this point was Phil May, Wally Waller, John Povey, Vic Unitt, and Skip Alan.
In 1975, the record was packaged as a double LP with their previous album S.F. Sorrow titled S.F. Sorrow and Parachute and issued on the UK label Harvest on the Harvest Heritage series. In 1976, the record was again packaged as a double LP with their previous album S.F. Sorrow titled Real Pretty. In Canada, this album was on Motown Records.
Snapper Records released a 40th anniversary double CD in September 2010 which included acoustic reworkings of various tracks recorded in May 2010 by Wally Waller and Phil May.

## Track listing

All songs by Phil May and Wally Waller, except where noted. Adapted from original UK pressing.
* Note: many subsequent pressings of the album separated the medleys on Side A into three tracks each.

### Bonus tracks on 2000 reissue

* "Blue Serge Blues" (May, Waller, Jon Povey) – 3:55
* "October 26" – 4:57
* "Cold Stone" (May, Waller, Pete Tolson) – 3:11
* "Stone–Hearted Mama" – 3:29
* "Summer Time" (May, Waller, Tolson) – 4:29
* "Circus Mind" (May, Tolson) – 2:00

## Personnel

Pretty Things
* Phil May – vocals
* Vic Unitt – guitars [album tracks only]
* Wally Waller – bass, guitar, vocals
* Jon Povey – keyboards, vocals
* Skip Alan – drums
* Pete Tolson – guitars [bonus tracks only]
Technical
* Tony Clark – engineer
* Nick Webb – assistant engineer
* Hipgnosis – cover design, photography
# Universomo

Universomo Ltd. was a Finnish video game developer based in Tampere, Finland, founded in 2002, and acquired by THQ on May 9, 2007. Universomo also had offices in Helsinki, Finland and San Diego, United States. The studio focused on games for mobile phones, the iPhone and the N-Gage. On January 12, 2010, THQ announced the Nintendo DS title Beat City, developed by Universomo, marking the developer's first entry to the handheld gaming market.
On March 2, 2010, Universomo's closure was announced. This left THQ Wireless without any studios under its umbrella, and development of its games would be outsourced to external studios.
Universomo was best known for the favorably reviewed mobile and iPhone versions of de Blob, the mobile, iPhone and N-Gage versions of Star Wars: The Force Unleashed and the mobile versions of Lego Star Wars: The Video Game.

## Games

* Beat City
* Star Wars: Cantina Dash
* WWE Smackdown vs. Raw 2010
* Treasure Grab
* Indiana Jones and the Lost Puzzles
* Up
* Prison Tycoon
* Star Wars: The Clone Wars
* Wall-E
* Pass The Pigs
* Chop Sushi!
* Super Fruitfall
* Star Wars: The Force Unleashed
* de Blob
* Indiana Jones and the Kingdom of the Crystal Skull
* Puzzle Quest: Warlords
* Playboy Pool Party
* Snood Blaster
* Ratatouille: Cheese Rush
* Destroy All Humans! Crypto Does Vegas
* MX vs. ATV: Untamed
* Juiced 2
* Stuntman Ignition
* Ocean's 13
* Emergency Mayhem
* 300: The Mobile Game
* Lego Star Wars
* Lego Star Wars II Mobile
* Stones of Khufu
* Destroy All Humans! 2
* Rollercoaster Rush
* Magic Inlay
* Bionicle Heroes
* Juiced Eliminator
* Bounce Out
* Gorillaz Entertainment System
* Habbo Creatures
* Habbo Dreams
* Get Rich or Die Tryin'
* Gem Drop
* PileUp!
* Star Wars Battle Above Coruscant
* Stunt Plane
* Sumo Smash!
* Jumbo Rumble
* Bones Adventuring Co.
* Trails of Terror - Mutiny
* Kloner - Together in the Dark
* Bones - The First Adventure
# Ptychoptera sculleni

Ptychoptera sculleni is a species of phantom crane flies in the family Ptychopteridae. It can be found in the far western portion of the United States, namely the states of California, Oregon, and Washington.
# Edward Cardillo

Edward Cardillo is an American politician. He serves as a Democratic member for the 42nd district of the Rhode Island House of Representatives.
Cardillo attended at Cranston High School West, where he graduated in 1973. He worked as a mechanic. In 2021, Cardillo was elected for the 42nd district of the Rhode Island House of Representatives. He succeeded Stephen Ucci. Cardillo assumed office on January 5, 2021.
Cardillo lost his 2024 Democratic primary to Kelsey Coletta. Cardillo's nephew, Dennis Cardillo Jr., ran against him in the 2022 and 2024 Democratic primaries.
# Indoreonectes

Indoreonectes is a genus of stone loaches native to the Western Ghats in India.

## Species

Indoreonectes contains the following valid species:
* Indoreonectes evezardi (Day, 1872)
* Indoreonectes keralensis Rita & Nalbant, 1978)
* Indoreonectes neeleshi Kumkar, Pise, Gorule, Verma & Kalous, 2021
* Indoreonectes rajeevi Kumkar, Pise, Gorule, Verma & Kalous, 2021
* ndoreonectes telanganaensis Prasad, C. Srinivasulu, A. Srinivasulu, Anoop & Dahanukar, 2020
# AP-7 (drug)

AP-7 is a selective NMDA receptor (NMDAR) antagonist that competitively inhibits the glutamate binding site and thus activation of NMDAR. It has anticonvulsant effects.
AP-7 functions specifically as a NMDA recognition site blocker, in contrast with 7-chlorokynurenate, which acts as a glycine site modulation blocker.

## Animal studies

AP-7 injected directly into the dorsal periaqueductal grey (DPAG) of rats produced an anxiolytic effect, whereas direct injection outside of the DPAG did not elicit anxiolytic effects, suggesting that the anxiolytic effect of NMDA antagonists in rats may depend on their action in the DPAG.
The DPAG of the brain is thought to deal with fear-like defensive behavior via NMDA and glycine B receptors. These excitatory glutamate receptors work with the inhibitory GABA receptors to achieve equilibrium in the DPAG of the brain.
AP-7 has been known to cause muscle rigidity and catalepsy in rats following bilateral microinjections (0.02-0.5 nmol) into the globus pallidus and ventral-posterior portions of the caudate-putamen.
The optically pure D-(−)-2-amino-7-phosphonoheptanoic acid [D-AP7], has also been examined. In groups of hypoxia-treated rats, D-AP7 enhanced motility, exhibited anxiogenic-like effect and impaired consolidation in passive avoidance. Both AP-7 and D-AP7 function as potent, specific antagonists of the NMDA receptor.