OpenLLM-France/wikimedia huggingface dataset:
# Grazoprevir

Grazoprevir is a drug approved for the treatment of hepatitis C. It was developed by Merck and completed Phase III trials, used in combination with the NS5A replication complex inhibitor elbasvir under the trade name Zepatier, either with or without ribavirin.
Grazoprevir is a second generation hepatitis C virus protease inhibitor acting at the NS3/4A protease targets. It has good activity against a range of HCV genotype variants, including some that are resistant to most currently used antiviral medications.

## Side effects

Side effects have only been assessed in the combination with elbasvir. Common side effects of the combination include feeling tired, nausea, reduced appetite, and headache. Low red blood cell count has occurred when co-administered with ribavirin in some cases. The most important risks are alanine transaminase elevation, hyperbilirubinemia, drug resistance development and drug interactions.

## Interactions

Grazoprevir is transported by the solute carrier proteins SLCO1B1 and SLCO1B3. Drugs that inhibit this proteins, such as rifampicin, ciclosporin, and a number of AIDS medications (atazanavir, darunavir, lopinavir, saquinavir, tipranavir, cobicistat), can cause a significant increase in grazoprevir blood plasma levels. The substance is degraded by the liver enzyme CYP3A4. Combination with drugs that induce this enzyme, such as efavirenz, carbamazepine or St. John's wort, can lead to ineffectively low plasma levels of grazoprevir. Combination with CYP3A4 inhibitors may increase plasma levels.

## Pharmacology
### Mechanism of action

Grazoprevir blocks NS3, a serine protease enzyme the virus needs for splitting its polyprotein into the functional virus proteins, and NS4A, a cofactor of NS3.

### Pharmacokinetics

Grazoprevir reaches peak plasma concentrations two hours after oral intake together with elbasvir (variation between patients: 30 minutes to three hours). In hepatitis C patients, steady state concentrations are found after about six days. Plasma protein binding is 98.8%, mainly to albumin and alpha-1-acid glycoprotein. Part of the substance is oxidised in the liver, largely by the enzyme CYP3A4. The biological half-life is 31 hours on average. Over 90% are excreted via the faeces, and less than 1% via the urine.
# Yuri Steklov

Yuri Mikhailovich Steklov (Russian: Юрий Михайлович Стеклов; born Ovshey Moiseyevich Nakhamkis; Russian: Овший Моисе́евич Наха́мкис; 27 August [O.S. 15 August] 1873, Odessa – 15 September 1941, Saratov) was a Russian revolutionary, Soviet politician, journalist, editor and historian.
Steklov joined the Bolshevik faction of the Russian Social Democratic Labour Party in 1903 and became editor of Izvestia of the Petrograd Soviet after the Russian Revolution. He wrote biographies of Mikhail Bakunin and Alexander Herzen, as well as commentary on Karl Marx and Vladimir Lenin.
Steklov was arrested in February 1938 amid the Great Purge. After the outbreak of World War II on the Eastern Front, he was transferred to the Saratov prison, where he died on September 15, 1941, from dysentery and extreme exhaustion at the age of 68. He was posthumously rehabilitated in 1956.

## Works

* Michael Bakunin: ein Lebensbild, Stuttgart: J.H.W. Dietz, 1913
* A. J. Herzen: eine Biographie, Berlin: A. Seehof, 1920.
* History of the first International, London: M. Lawrence, [1928]. Translated by Cedar and Eden Paul from the 3rd Russian ed., with notes from the 4th ed.
# Ivan Yakovlevich Yukhimenko

Ivan Yakovlevich Yukhimenko (Ukrainian: Іван Якович Юхименко; 2 October 1892, Kharkiv – 6 February 1943, Kazan) was a Soviet actor, director and teacher, Merited Artist of Ukrainian SSR. It is thought that he died during the Kharkiv tragedy.
# Leon Șușman

Leon Șușman (June 10, 1910 – July 19, 1957) was a member of the fascist paramilitary organization the Iron Guard who, following the Soviet occupation of Romania and establishment of the Romanian People's Republic, became the leader of an anti-communist paramilitary group in the Apuseni Mountains.
Șușman was born in Măhăceni, Alba County on June 10, 1910, in a family of Greek-Catholic peasants. After graduating with a law degree from the University of Cluj, he joined the Iron Guard. In 1941 he was sentenced to 10 years in prison for his participation in the Legionnaires' rebellion and Bucharest pogrom; however, he escaped capture and fled to the Apuseni Mountains. In 1945, following an agreement between Iron Guard leader Nicolae Petrașcu and Interior Minister Teohari Georgescu which granted Iron Guard members amnesty in exchange for turning in their weapons, Șușman returned to civilian life and practiced law in Ocna Mureș; he did so until May 15, 1948, when the Communist authorities started to arrest ex-members of the Iron Guard and fascist sympathizers.
At that time, Leon and his brother, Gheorghe Șușman, went underground, hiding from the authorities in the area between Turda, Ocna Mureș, Aiud, and Blaj. From 1949 to 1950 Leon led an anti-communist paramilitary group in the Măhăceni–Aiud area. Between 1950 and 1957, he was the leader of the resistance group in the Poșaga area, together with the Greek-Catholic priest Simion Roșa. The Securitate secret police sent 10 officers in the area, headed by Major Constantin Vieru, under cover of being geologists. To eliminate the Șușman resistance group, the Romanian security forces used informers against them and intercepted the correspondence of family members. One informer, code-named "Maxim Ionescu", informed the Securitate that the Șușman brothers were going to celebrate Saint Elijah together with Ilie Brad and Simion Roșa in the house of Vasile Crișan from the Poșaga village of Săgagea. Șușman died in Poșaga de Sus of wounds sustained in a shootout with Securitate troops during the night of July 18–19, 1957. Roșa also died that night, as did the chief of the Securitate detachment; two other members of the resistance group, Gheorghe Șușman and Crișan, were caught alive.
In the aftermath of the Poșaga shootout, dozens of supporters of the Șușman–Roșa anti-communist resistance group were arrested and tried by the Cluj Military Tribunal. Gheorghe Șușman and Vasile Crișan were sentenced to death in April 1958; they were both executed at Gherla Prison on August 4 of that year. Also executed at Gherla around that time were Ilie Vlad, Teodor Trânca, Vasile Răfăilă, and Andrei Bicuț, peasants from the area found guilty of being supporters of the Șușman group. Others were sent to prison, and numerous families were deported to the Bărăgan and had their properties confiscated.
# Mark Salazar

Mark Pegenia Salazar (Tagalog pronunciation:; born September 26, 1977) is a Filipino journalist, television news producer, newscaster, field reporter, & host. He is currently serving as the co-host of iJuander on GTV and the radio program Usap Tayo: Super Kwentuhan with Mark and Susan on DZBB-AM, both alongside Susan Enriquez.

## Career

Salazar started out as a news producer of GMA Network in 2001. He became part of GMA News as a journalist since 2005. He was also an associate producer for 24 Oras Weekend.
He anchored Balita Pilipinas Ngayon with Maki Pulido from 2011 until its conclusion in 2019. Salazar also anchored the weekend edition of Balitanghali with Mav Gonzales, replacing the original anchors Mariz Umali and Jun Veneracion who both left. The weekend newscast was canceled in March 2020 due to the COVID-19 pandemic.
In February 2021, he joined Susan Enriquez as the co-host of iJuander, two years after Enriquez went solo due to the passing of her original co-host, Cesar Apolinario.
# Witton, North Norfolk

Witton is a village and civil parish in the English county of Norfolk. It is located 8 km (5.0 mi) east of the town of North Walsham and 30 km (19 mi) north of the city of Norwich. It should not be confused with the quite different Norfolk village of similar name in the parish of Postwick with Witton, some 8 km (5.0 mi) east of Norwich.
The villages name means 'wood farm/settlement'.
The civil parish (officially known as Witton) also includes the village of Ridlington and has an area of 9.77 km$^2$ (3.77 sq mi) and in the 2001 census had a population of 298 in 134 households, increasing to a population of 318 in 141 households at the 2011 Census. For the purposes of local government, the parish falls within the district of North Norfolk.
The parish church of St. Margaret has a round tower, making it one of the many round-towered churches in Norfolk and Suffolk.
# Parkline Place

Parkline Place is a skyscraper in Sydney, Australia built as one of the two buildings that form a part of Sydney Metro's 'integrated station and precinct development' (ISD) plan for Gadigal railway station. The design by Foster + Partners, for a 39-storey office building and retail plaza, was inspired by the Bloomberg Building in London and Hearst Tower (Manhattan) in New York and stands at a height of 155 metres (509 ft).

## History

On 11th September 2019, the NSW Government awarded the contract for the Sydney Metro Pitt Street Metro Station 'over station development' (OSD) project to the consortium assembled by Grocon.
On 4th of March 2021, the consortium obtained approval from the NSW Government for development application 'SSD 10375 Pitt Street North Over Station Development Stage 2'. Construction works of the building, designed by architecture firm Foster + Partners, started in 2021 and will be completed in 2024.
In April 2023, BDO Global announced the lease of levels 22 to 25 as their new offices.
In January 2024, it was announced that Insignia Financial secured signage rights to the building and has leased levels 16 to 21.
In October 2024, it was reported that construction was delayed due to industrial action putting the project 3 months behind schedule.

## Construction

CPB Contractors was confirmed as the builder of the commercial building as well as the builder for the wider construction project for the new Gadigal railway station along the new Sydney Metro City & Southwest Line that sits beneath the building, and the accompanying build-to-rent residential tower.
# 1999 World Championships in Athletics – Men's 10,000 metres

The men's 10,000 metres event featured at the 1999 World Championships in Seville, Spain. The final was held on 24 August 1999.

## Final ranking

Source:
| RANK | ATHLETE | TIME |
| | Haile Gebrselassie (ETH) | 27:57.27 |
| | Paul Tergat (KEN) | 27:58.56 |
| | Assefa Mezgebu (ETH) | 27:59.15 |
| 4. | Girma Tolla (ETH) | 28:02.08 |
| 5. | António Pinto (POR) | 28:03.42 |
| 6. | Habte Jifar (ETH) | 28:08.82 |
| 7. | Benjamin Maiyo (KEN) | 28:14.98 |
| 8. | Kamiel Maase (NED) | 28:15.58 |
| 9. | David Chelule (KEN) | 28:17.77 |
| 10. | Khalid Skah (MAR) | 28:25.10 |
| 11. | Hendrick Ramaala (RSA) | 28:25.57 |
| 12. | Toshinari Takaoka (JPN) | 28:30.73 |
| 13. | João N'Tyamba (ANG) | 28:31.09 |
| 14. | Enrique Molina (ESP) | 28:37.19 |
| 15. | Ismaïl Sghyr (MAR) | 28:41.49 |
| 16. | Saïd Berioui (MAR) | 28:46.77 |
| 17. | Mohamed Ezzher (FRA) | 28:47.01 |
| 18. | Kenji Takao (JPN) | 28:49.95 |
| 19. | José Manuel Martínez (ESP) | 28:55.87 |
| 20. | Satoshi Irifune (JPN) | 29:04.09 |
| 21. | Brad Hauser (USA) | 29:18.21 |
| 22. | Pete Julian (USA) | 29:20.31 |
| 23. | Enoch Skosana (RSA) | 29:30.51 |
| 24. | Alejandro Salvador (MEX) | 29:36.58 |
| 25. | Bruno Toledo (ESP) | 29:39.28 |
| 26. | Sean Kaley (CAN) | 29:52.35 |
| 27. | Samir Moussaoui (ALG) | 30:20.24 |
| | Shadrack Hoff (RSA) | DNF |
| | Alan Culpepper (USA) | DNF |
| | Jon Brown (GBR) | DNF |
| | Ali Mabruk El-Zaidi (LBA) | DNF |
| | Mohamed Al-Khawlani (YEM) | DNF |
# Aaron Ruell

Derek Aaron Ruell (born June 23, 1976) is an American director, photographer and actor. He is most recognized for his performance as Kip Dynamite in the indie movie Napoleon Dynamite.

## Early life and education

Ruell was born in Fresno, California and raised in a Mormon family in the nearby town of Clovis. After graduation from Clovis West High School, Ruell studied film at Brigham Young University.

## Career
### Director

Ruell is an accomplished commercial director and photographer. As a director he is represented by Sanctuary in Los Angeles. He was declared one of the most promising new directors in the world of advertising by Shoot magazine in 2009, and "one of the emerging directors to know now" by Creativity. He has directed commercials for clients such as T-Mobile, Nintendo, Coke, and Burger King.
He was the only filmmaker to have two films, Everything's Gone Green and Mary, which he wrote and directed, premiere at the 2005 Sundance Film Festival.

### Actor

Ruell is best known for playing the role of Kipland Dynamite in the movie Napoleon Dynamite. In 2007, he starred in On the Road with Judas, which premiered in the Dramatic Competition section of the 2007 Sundance Film Festival. Ruell played a successful New York businessman who led a double life as a computer thief.

## Personal life

Ruell and his wife, Julia Yuka Ruell, were at one time members of the Los Angeles Latebirds, an official Moped Army branch. They currently reside in Portland, Oregon after having resided in Pasadena, California.

## Filmography

Film :
| Year | Film | Role | Other notes |
| 2004 | Napoleon Dynamite | Kipland Ronald "Kip" Dynamite | |
| 2006 | The Problem with Percival | Social Worker | Short film |
| 2006 | Think Tank | | |
| 2007 | On the Road with Judas | Judas | |
| Television ||||
| Year | Title | Role | Notes |
| 2005 | Super Robot Monkey Team Hyperforce Go! | Suupa | Voice Role Episode: Brothers in Arms |
| 2012 | Napoleon Dynamite | Kipland Ronald "Kip" Dynamite | Voice Role Regular |

## Awards and nominations

Teen Choice Awards
* 2005: Nominated, "Choice Movie Rockstar Moment" - Napoleon Dynamite
# Aaron Atayde

Aaron Joshua "Josh Strike" Atayde (born March 10, 1986) is a DJ, TV host, and sports anchor for ABS-CBN Sports' coverage of the UAAP. He is now sports anchor for UFL on AKTV and doing courtside reportage for PBA.

## Life and career

Atayde is a son of Tony the Green Mind, and a brother to [ Pernod Ricard Marketing Director HongKong and Macau, Tony Atayde.
Atayde is a graduate of AB Communication Arts in De La Salle University. He started his career as a courtside reporter for UAAP Seasons 70 and 71 for Adamson University Soaring Falcons. After serving for 2 years, he went-on to be part of the play-by-play panel since 2009.
He hosts the Quick-E technology show for Studio 23.
Atayde started out as one of the Junior Jocks of Magic 89.9 radio for the year 2007. He uses the moniker, "Josh Strike".
He has done courtside reporting for PBA on AKTV and being the main presenter of UFL.
He was also one of the host for "SLAMRadioPH", A weekly podcast about the PBA in slamonlineph.com.

## Filmography
### TV

* Wildcard (2008–2010) ABS-CBN Sports
* Quick-E (2009–2010) Studio 23
* Pa-Bida Ka! (2010–2011) Studio 23
* PBA on AKTV (2011–2014) AKTV
* UFL (2011–2013) AKTV
* NCAA on Sports5 (2012-2014) AKTV
* PBA Money Ball: Dribol of Da Pipol (2014) TV5
* PBA on TV5 (2014–present) as commentator TV5
* Sports5 Center (2015–2017) as co-host TV5
* Rio Olympics Special Coverage on TV5 (2016) TV5
* SportsCenter Philippines (2017–2020) as Sports news anchor ESPN5, TV5
* Geeks and Gamers Guide (2020–2022) One Sports, GG Network

### Radio

* The Strike Zone (2007–present)
* Magic Weekend (2008–present)
* The Rundown (2015–present)
* Magic 30 (2008–2011)
# Sheree Bautista

Cherry Hazel Sweet Faye Vidal Bautista (born April 20, 1980), popularly known as Sheree, is a Filipino actress, singer, dancer, model, and painter.
Born in Cagayan de Oro and raised in Bukidnon, she is a former member of Viva Hot Babes. She is a cousin of Jinky Vidal, formerly of Freestyle, and a distant relative of Mark Bautista.
Sheree has a son with theater actor and singer Gian Magdangal whom she is separated with.

## Filmography
### Television / Digital Series

| Year | Title | Role | Network |
| 2002 | Habang Kapiling Ka | Magnolia | GMA Network |
| 2007 | Kemis: Ke Misis Umaasa | Armi | RPN |
| 2007 | Lupin | Virgin | GMA Network |
| 2008 | Codename: Asero | Agent Malta (Codename: Tiger Lady) | GMA Network |
| 2008–2009 | Luna Mystika | Engkanto | GMA Network |
| 2009 | Rosalinda | Natalia | GMA Network |
| 2010–2011 | Imortal | Young Lucille Zaragoza | ABS-CBN |
| 2011 | Iglot | Gardo's wife | GMA Network |
| 2012 | Makapiling Kang Muli | Ara | GMA Network |
| 2012 | My Beloved | Tikyo's girlfriend | GMA Network |
| 2016 | Juan Happy Love Story | Lucy | GMA Network |
| 2016 | Karelasyon | Casey | GMA Network |
| 2016 | A1 Ko Sa 'Yo | Beverly Reyes | GMA Network |
| 2016 | Oh, My Mama! | Patricia Ynares | GMA Network |
| 2017 | Pinulot Ka Lang sa Lupa | Arlene Garela-Alejo | GMA Network |
| 2017 | Road Trip | Herself / Guest | GMA Network |
| 2017 | Encantadia | Hera Odessa | GMA Network |
| 2017–2018 | Kambal, Karibal | Lilian Ocampo | GMA Network |
| 2018–2019 | Kadenang Ginto | Jessa Trinidad | ABS-CBN |
| 2020 | Bawal na Game Show | Herself / Contestant | TV5 |
| 2022 | Flower of Evil | Monet Dimayuga | Viu, Kapamilya Channel |
| 2023 | Sex Games | Debbie | Viva Films |
| 2024 | Black Rider | Dolores† | GMA Network |
# Alberto Cinta

Alberto Emiliano Cinta Martínez (born in Mexico City) is a Mexican economist, entrepreneur and politician who is a founder and became the first general secretary of the New Alliance Party (PANAL). He ran as the PANAL's candidate for Mayor of Mexico City Head of Government of the Federal District in the 2006 Federal District election. He has been a Congressman, public servant, university professor and entrepreneur. He studied economics at the ITAM in Mexico City, and holds two master's degrees from both the Ecole Nationale d'Administratuon (ENA, Paris) and Harvard (KSG, Massachusetts). He has been a deputy at the Chamber of Deputies for the Green Party and president of the Special Commission of Competitiveness (2009-2012) and also a deputy for Mexico City (2012-2015). Since 2001 he is the founder and chairman of a leading Mexican hospitality group that operates more than fifty high-end restaurants, nightclubs, business clubs, and concert halls. In 2014 his group started operations in the US with the opening of its first restaurant (Cantina La Veinte), in Miami.

## Personal life and education

Cinta is the son of lawyer Alberto Cinta Guzmán. He holds a bachelor's degree in economics from the Instituto Tecnológico Autónomo de México (ITAM) where he studied from 1989 to 1993. From 1994 to 1995 he pursued graduate studies at the École Nationale d'Administration (ENA) where he received a master's degree in public administration and political economy. He also holds a master's degree in public administration from Harvard University. He has participated in academic publications such as "Towards Mexico's Democratization" (Routledge 1999) and "México Visión Global, la agenda para el siglo XXI" (Porrúa, 2006), among others.
He is the founder and chairman of the Board of Directors of Cinbersol S.A., the leading company for high end hospitality in Mexico that operates several restaurants, concert halls and clubs in Mexico and the US such as "Club Piso 51", Landó Grill, Restaurante Lamm, "50 Friends", "Sud 777", Ivoire and "Cantina La Veinte" among others.

## Professional career

In 1991 Cinta joined the public service working for the President of the Republic's office as Director of public opinion analysis under President Carlos Salinas de Gortari. He also joined the office of the President Ernesto Zedillo of the PRI, as General Director of Research and Analysis (1995–1997). From 1999 to 2000 he served as advisor for Francisco Labastida's presidential campaign (PRI). From 2003 to 2005 he served as General Director of the Centro de Estudios Sociales y de Opinión Pública of the Chamber of Deputies.
# London Buses route 497

London Buses route 497 was a Transport for London contracted bus route in London, England. It ran between Harold Hill and Harold Wood station, and was operated by Stagecoach London.

## History

The route was first proposed in a review by Transport for London published in September 2016. A two-month consultation was held in 2017. It had been expected to start service in May 2019, however it was delayed. It began service on 25 January 2020. A review found that passenger numbers were insufficient for the route to be sustainable. In autumn 2021, Transport for London opened a consultation requesting opinions on if the route should be extended, or withdrawn.
In March 2022, Transport for London confirmed that the Sunday service would be withdrawn in the summer and that the route would be extended to Dagnam Park Square.
In January 2024, following a public consultation, Transport for London confirmed that the route would be withdrawn on 9 March 2024. It was replaced by an extension of route 346 that now serves all the same roads and stops formerly served by route 497.
On 9 March 2024, the route was withdrawn.

## Former route

Route 497 operated via these primary locations:
* Harold Wood station
* Gallows Corner Tesco
* Harold Hill Hilldene Avenue
* Harold Hill Dagnam Park Square
# De Mûnts, Buitenpost

De Mûnts (English: The Monk) is a smock mill in Buitenpost, Friesland, Netherlands which has been restored to working order. The mill is listed as a Rijksmonument, number 7039.

## History

This mill was built in 1870 at Oosterhoogebrug, Groningen, where it drained the Borgsloterpolder in connection with the construction of the Eemskanal. It was demolished in 1952. In 1958, millwright A de Roos of Leeuwarden started to rebuild the mill at Buitenpost for Wolter O Bakker of Harkstede. This was completed in 1959. Repairs and restoration were carried out in 1963 and 1973. In 1985, the inner sailstock, which was made of wood, broke. It was replaced by an iron one by millwright Buurma of Oudeschans, Groningen. In 1990, the outer sailstock was also replaced with an iron on by Buurma. Further restoration work was carried out on the mill in 1994.

## Description

De Mûnts is a smock mill winded by a winch. There is no stage, the sails reaching almost to the ground. The mill has a single-storey brick base and a three-storey smock. The smock and cap are thatched. The four Common sails have a span of 13.40 metres (44 ft 0 in) and are carried in a wooden windshaft. The windshaft also carries the brake wheel, which has 37 cogs. This drives the wallower (19 cogs) at the top of the upright shaft. At the bottom of the upright shaft, the crown wheel (28 cogs) drives the wooden Archimedes' screw via a gear wheel with 29 cogs. The Archimedes' screw has an axle diameter of 210 millimetres (8¼ in) and is 650 millimetres (2 ft 2 in) diameter overall. It is inclined at an angle of 15°. Each revolution of the screw lifts 106 litres (23 imp gal) of water.

## Public access

De Mûnts is open to the public when the mill is working, or by appointment.
# Livia Lang

Livia Lang (born 3 June 1994) is an Austrian synchronized swimmer. She competed in the women's duet at the 2012 Summer Olympics.
# Irish penal rosary

The Irish Penal Rosary (Irish: An Paidrín Beag) was a single-decade rosary used during penal times in Ireland, when Roman Catholicism and its religious objects were forbidden. This version of the rosary is easily hidden, allowing devout Roman Catholics to pray with less fear of being detected.

## Description

The crucifix has various symbols of the Passion: a hammer for the nails of the cross; a halo for the Crown of Thorns; a jug symbolizing the Last Supper; cords for binding which recall the Scourging at the Pillar; the spear used at Calvary; a cock and pot, which illustrates an early apocryphal legend relating to Judas the betrayer, and a roasting cock which suddenly came to life and crowed (thus prophesying the Resurrection); and three nails used for the crucifix. Small marks along the side of the corpus indicate a ladder, both for the ladder used in the crucifixion and a metaphor for ascent into heaven.

## Usage

The crucifix is hidden inside the sleeve or palm, while the ring is placed over the thumb as the first decade of the rosary is recited. The ring is then placed over the next finger as the next decade is spoken and so on until the five decades are completed.