# 2022 U.S. Pro Women's Clay Court Championships – Singles

Barbora Krejčíková was the defending champion but chose not to participate.
Katie Volynets won the title, defeating Wang Xiyu in the final, 6–4, 6–3.

## Seeds

* Wang Xinyu (first round)
* Astra Sharma (withdrew)
* Irina Bara (semifinals)
* Hailey Baptiste (first round)
* Wang Xiyu (final)
* Alycia Parks (second round)
* Anastasia Gasanova (first round)
* Katie Volynets (champion)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 5 | Wang Xiyu | 6 | 6 | | | | |
| LL | Louisa Chirico | 3 | 2 | | | | |
| LL | Louisa Chirico | 3 | 2 | 5 | Wang Xiyu | 4 | 3 |
| | | | | 8 | Katie Volynets | 6 | 6 |
| 3 | Irina Bara | 3 | 2 | 8 | Katie Volynets | 6 | 6 |
| 8 | Katie Volynets | 6 | 6 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | Xin Wang | 6$^3$ | 6 | 3 | | | | | | | | | | | | | | |
| WC | S Chang | 7$^7$ | 3 | 6 | WC | S Chang | 6 | 6 | | | | | | | | | | |
| | R Anderson | 4 | 4 | | Q | S Mendez | 0 | 4 | | | | | | | | | | |
| Q | S Mendez | 6 | 6 | | | | | | | WC | S Chang | 7 | 4 | 4 | | | | |
| | N Hibino | 4 | 2 | | | | | | | 5 | Xiy Wang | 5 | 6 | 6 | | | | |
| | A Cadanțu-Ignatik | 6 | 6 | | | A Cadanțu-Ignatik | 5 | 1 | | | | | | | | | | |
| | L Stefanini | 5 | 0 | | 5 | Xiy Wang | 7 | 6 | | | | | | | | | | |
| 5 | Xiy Wang | 7 | 6 | | | | | | | | | | | | 5 | Xiy Wang | 6 | 6 |
| 4/WC | H Baptiste | 3 | 3 | | | | | | | | | | | | LL | L Chirico | 3 | 2 |
| LL | L Chirico | 6 | 6 | | LL | L Chirico | 4 | 6 | 6 | | | | | | | | | |
| WC | P Stearns | 6 | 6$^2$ | 7 | WC | P Stearns | 6 | 4 | 4 | | | | | | | | | |
| Q | MJ Portillo Ramírez | 3 | 7$^7$ | 5 | | | | | | LL | L Chirico | 5 | 6 | 6 | | | | |
| Q | G Lee | 7 | 0 | | | | | | | Q | G Lee | 7 | 4 | 2 | | | | |
| | C Vandeweghe | 5 | 0$^r$ | | Q | G Lee | 7$^7$ | 6 | | | | | | | | | | |
| | C Dolehide | 4 | 1 | | 6 | A Parks | 6$^4$ | 3 | | | | | | | | | | |
| 6 | A Parks | 6 | 6 | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 7 | A Gasanova | 2 | 7 | 4 | | | | | | | | | | | | | |
| | G Min | 6 | 5 | 6 | | G Min | 7 | 6 | | | | | | | | | |
| | V Grammatikopoulou | 4 | 6 | 6 | | V Grammatikopoulou | 5 | 2 | | | | | | | | | |
| Q | W Osuigwe | 6 | 2 | 4 | | | | | | G Min | 3 | 4 | | | | | |
| Q | E Kalieva | 0 | 6 | 6 | | | | | 3 | I Bara | 6 | 6 | | | | | |
| | O Govortsova | 6 | 3 | 4 | Q | E Kalieva | 3 | 2 | | | | | | | | | |
| | F Di Lorenzo | 3 | 3 | | 3 | I Bara | 6 | 6 | | | | | | | | | |
| 3 | I Bara | 6 | 6 | | | | | | | | | | | 3 | I Bara | 3 | 2 |
| 8 | K Volynets | 6 | 6 | | | | | | | | | | | 8 | K Volynets | 6 | 6 |
| Q | S Djoubri | 1 | 2 | | 8 | K Volynets | 6 | 6 | | | | | | | | | |
| | K Nara | 7$^7$ | 1 | 6 | | K Nara | 4 | 4 | | | | | | | | | |
| LL | C Harrison | 6$^2$ | 6 | 4 | | | | | 8 | K Volynets | 7 | 4 | 6 | | | | |
| WC | T Townsend | 6 | 6 | | | | | | WC | T Townsend | 5 | 6 | 0 | | | | |
| Q | H Chang | 2 | 2 | | WC | T Townsend | 7$^7$ | 6 | | | | | | | | | |
| | M Björklund | 6 | 6 | | | M Björklund | 6$^5$ | 4 | | | | | | | | | |
| Q | M Manasse | 1 | 2 | | | | | | | | | | | | | | |