# 2022 Las Vegas Challenger – Singles

J. J. Wolf was the defending champion but chose not to defend his title.
Tennys Sandgren won the title after defeating Stefan Kozlov 7–5, 6–3 in the final.

## Seeds

* Denis Kudla (first round)
* Steve Johnson (semifinals)
* Vasek Pospisil (first round)
* Stefan Kozlov (final)
* Juan Pablo Ficovich (quarterfinals, retired)
* Ben Shelton (second round)
* Facundo Mena (first round)
* Aleksandar Kovacevic (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| | Shang Juncheng | 3 | 6$^5$ | | | | | |
| Q | Tennys Sandgren | 6 | 7$^7$ | | | | | |
| Q | Tennys Sandgren | 6 | 7$^7$ | | Q | Tennys Sandgren | 7 | 6 |
| | | | | | 4 | Stefan Kozlov | 5 | 3 |
| 4 | Stefan Kozlov | 6 | 1 | 7 | 4 | Stefan Kozlov | 5 | 3 |
| 2 | Steve Johnson | 3 | 6 | 5 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | D Kudla | 4 | 3 | | | | | | | | | | | | | | | |
| Q | A Perez | 6 | 6 | | Q | A Perez | 6$^3$ | 6 | 3 | | | | | | | | | |
| | J Shang | 6 | 3 | 6 | | J Shang | 7$^7$ | 4 | 6 | | | | | | | | | |
| WC | A Cozbinov | 4 | 6 | 3 | | | | | | | J Shang | 6 | 3 | 6 | | | | |
| | E Escobedo | 6 | 6 | | | | | | | | E Escobedo | 4 | 6 | 3 | | | | |
| Q | O Kumar | 1 | 4 | | | E Escobedo | 6 | 6 | | | | | | | | | | |
| | V Vacherot | 7$^7$ | 6$^4$ | 4 | 6 | B Shelton | 2 | 3 | | | | | | | | | | |
| 6 | B Shelton | 6$^4$ | 7$^7$ | 6 | | | | | | | | | | | | J Shang | 3 | 6$^5$ |
| 3 | V Pospisil | 4 | 6 | 2 | | | | | | | | | | | Q | T Sandgren | 6 | 7$^7$ |
| Q | J Pinnington Jones | 6 | 3 | 6 | Q | J Pinnington Jones | 5 | 3 | | | | | | | | | | |
| Q | T Sandgren | 3 | 7 | 6 | Q | T Sandgren | 7 | 6 | | | | | | | | | | |
| | S Fanselow | 6 | 5 | 3 | | | | | | Q | T Sandgren | 6$^7$ | 6 | 6 | | | | |
| WC | Maxim Verboven | 2 | 2 | | | | | | | | B Holt | 7$^9$ | 2 | 3 | | | | |
| | B Holt | 6 | 6 | | | B Holt | 7$^7$ | 7 | | | | | | | | | | |
| | Em Nava | 6$^7$ | 2 | | 8 | A Kovacevic | 6$^1$ | 5 | | | | | | | | | | |
| 8 | A Kovacevic | 7$^9$ | 6 | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 7 | F Mena | 1 | 6 | 4 | | | | | | | | | | | | | | | |
| | A Galarneau | 6 | 0 | 6 | | A Galarneau | 6 | 2 | | | | | | | | | | | |
| Alt | G Nanda | 7$^7$ | 6 | | Alt | G Nanda | 1 | 1$^r$ | | | | | | | | | | | |
| | N Mejía | 6$^1$ | 4 | | | | | | | | A Galarneau | 7$^7$ | 4 | 3 | | | | | |
| Q | A Mayo | 4 | 6$^9$ | | | | | | | 4 | S Kozlov | 6$^5$ | 6 | 6 | | | | | |
| | E Zhu | 6 | 7$^{11}$ | | | E Zhu | 6$^5$ | 2 | | | | | | | | | | | |
| WC | C Kingsley | 5 | 6 | 1 | 4 | S Kozlov | 7$^7$ | 6 | | | | | | | | | | | |
| 4 | S Kozlov | 7 | 4 | 6 | | | | | | | | | | | 4 | S Kozlov | 6 | 1 | 7 |
| 5 | JP Ficovich | 6 | 7 | | | | | | | | | | | | 2 | S Johnson | 3 | 6 | 5 |
| | P Jubb | 3 | 5 | | 5 | JP Ficovich | 3 | 7$^7$ | 6 | | | | | | | | | | |
| | G Diallo | 6 | 6 | | | G Diallo | 6 | 6$^5$ | 4 | | | | | | | | | | |
| | E Couacaud | 4 | 4 | | | | | | | 5 | JP Ficovich | 1 | 0$^r$ | | | | | | |
| | M Krueger | 7 | 6 | | | | | | | 2 | S Johnson | 6 | 0 | | | | | | |
| Q | S Carr | 5 | 4 | | | M Krueger | 5 | 3 | | | | | | | | | | | |
| | G Elias | 7 | 3 | 5 | 2 | S Johnson | 7 | 6 | | | | | | | | | | | |
| 2 | S Johnson | 5 | 6 | 7 | | | | | | | | | | | | | | | |