OpenLLM-France/wikimedia huggingface dataset:
# Pristinamycin

Pristinamycin (INN), also spelled pristinamycine, is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. It is a streptogramin group antibiotic, similar to virginiamycin, derived from the bacterium Streptomyces pristinaespiralis. It is marketed in Europe by Sanofi-Aventis under the trade name Pyostacine.
Pristinamycin is a mixture of two components that have a synergistic antibacterial action. Pristinamycin IIA is a macrolide, and results in pristinamycin's having a similar spectrum of action to erythromycin. Pristinamycin IA (streptogramin B) is a depsipeptide. PI and PII are coproduced by S. pristinaespiralis in a ratio of 30:70. Each compound binds to the bacterial 50 S ribosomal subunit and inhibits the elongation process of the protein synthesis, thereby exhibiting only a moderate bacteriostatic activity. However, the combination of both substances acts synergistically and leads to a potent bactericidal activity that can reach up to 100 times that of the separate components.
The pristinamycin biosynthetic gene cluster is the largest antibiotic supercluster known so far, with a size of ~210 kb, wherein the PI and PII biosynthetic genes are not clustered individually but are scattered across the complete sequence region. Furthermore, this biosynthetic gene region is interrupted by a cryptic type II PKS gene cluster.

## Medical use

Despite the macrolide component, it is effective against erythromycin-resistant staphylococci and streptococci. It is active against methicillin-resistant Staphylococcus aureus (MRSA). Its usefulness for severe infections, however, may be limited by the lack of an intravenous formulation owing to its poor solubility. Nevertheless, it is sometimes used as an alternative to rifampicin+fusidic acid or linezolid for the treatment of MRSA.
The lack of an intravenous formulation led to the development of the pristinamycin-derivative quinupristin/dalfopristin (i.e., Synercid), which may be administered intravenously for more severe MRSA infections.
# Korlagundi

Korlagundi is a village in the southern state of Karnataka, India. It is located in the Bellary taluk of Bellary district in Karnataka.

## Demographics

As of 2001 India census, Korlagundi had a population of 6240 with 3142 males and 3098 females.
# Rachel Tallent

Rachel Tallent (born 20 February 1993) is a female racewalker from Australia. She competed in the Women's 20 kilometres walk event at the 2015 World Championships in Athletics in Beijing, China. She also competed in the 2016 Olympics, while racing with a stress reaction in her left femur. She is the sister of Olympic Champion Jared Tallent who was previously her coach.
# James Nagle (hurler)

Jamie Nagle (born 26 October 1990) is an Irish hurler who plays for club side Midleton. He is a former member of the Cork senior hurling team.

## Career

A member of the Midleton club, Nagle first came to prominence at juvenile and underage levels while simultaneously playing with Midleton CBS in the Harty Cup. After captaining Midleton to the Cork U21HC title in 2011, he later won a Cork SHC title in 2013. Around this time Nagle also won consecutive Fitzgibbon Cup titles with University College Cork. He later linked up with the Midleton intermediate team. Nagle first appeared on the inter-county scene during an unsuccessful two-year stint with the Cork under-21 hurling team. He made his senior team debut in the pre-season Waterford Crystal Cup in 2010 and was included on the championship panel the following year.

## Career statistics

| Team | Year | National League | National League | National League | Munster | Munster | All-Ireland | All-Ireland | Total | Total |
| Team | Year | Division | Apps | Score | Apps | Score | Apps | Score | Apps | Score |
| Cork | 2010 | Division 1 | — | — | — | — | — | — | — | — |
| Cork | 2011 | Division 1 | 2 | 0-00 | 1 | 0-00 | 0 | 0-00 | 3 | 0-00 |
| Career total | Career total | Career total | 2 | 0-00 | 1 | 0-00 | 0 | 0-00 | 3 | 0-00 |

## Honours
### University College Cork

* Fitzgibbon Cup: 2012, 2013

### Midleton

* Cork Senior Hurling Championship: 2013
* Cork Under-21 Hurling Championship: 2011 (c)
# Utz

Utz or UTZ may refer to:

## Art and entertainment

* Utz (film), a 1992 film based on Bruce Chatwin's novel
* Utz (novel), Bruce Chatwin's 1988 novel, his last
* "Utz", a song by Enon from their 2003 album Hocus Pocus

## Other uses

* Utz (name), a list of people with the name
* UTZ Certified, a worldwide certification program for responsible coffee and other products
* Utz Brands, an American manufacturer of snack foods
* Utz Site, a Native American archeological site
* Utz Spur, a ridge in Antarctica
# Botany Sands Aquifer

The Botany Sands Aquifer is an aquifer that surrounds Botany Bay just south of Sydney, New South Wales, Australia. A former main water source for Sydney, it stretches from Centennial Park south east of Sydney CBD into Botany Bay to the south. The aquifer is chiefly filled by rainfall, some contributions from irrigation, seeping service mains and flow from the subjacent bedrock units.

## Description

The aquifer is a stratum of sand filled with groundwater which heads six kilometres downstream and is reloaded by rainwater pouring through sand and sandstone which act as natural filtrates to get rid of solid litter, silt and noxious nutrients. The salinity contains 500 milligrams per litre (mg/L) of melted solids. The aquifer is large, where it approximately contains 300 litres of water per cubic metre of sand, though only about 6,000ML/yr is portioned for use. The groundwater assist natural and manmade pond systems along its motion path, which exist in Centennial Park, the Royal Randwick Racecourse and ponds golf courses including Eastlakes and Mill Pond.

### Geology

There exist two groundwater systems: one within the bedrock successions of the Hawkesbury Sandstone and the other in the superimposed and loose sedimentary material, termed the BSB (Botany Sand Beds), which predominate the sedimentary array of the Botany Basin. Water levels vary between 0 and 25 metres beneath the surface, with the bulk of the geological Botany Basin exhibiting a mean depth of around 9 metres. The BSB has an average thickness of approximately 20 metres, with depths up to 53 metres in paleochannels engraved in the basement rocks. The sand beds are subordinated by clay and clay-rich quartz sand lenses and a primary unit consisting of fluvial and aeolian processed sands with gravel lenses.

## Use
### Historic

Before European settlement, the aquifer was an essential source of water for the aboriginal communities. In April 1770, Lieutenant James Cook and Sir Joseph Banks both discovered indigenous "huts" on the northern boundary of the bay and heaths which ascended to high sandy ridges. In 1815, a wool factory was constructed, adjoining the ponds north of Botany Bay, in addition to other industries being built in vicinity for their contaminated waste to enter the surface water and the groundwater.

### Present

Today, it still is a crucial source of water for parklands, public and residential gardens, industry and wetlands. Whilst the Botany Sands aquifer is still a key source of groundwater in Sydney’s Eastern Suburbs, the increasing use of land above the aquifer for industry, golf courses and garden watering, among other things, have caused the groundwater to become contaminated due to the industrial pollutants and is therefore unsafe for drinking. However, the aquifer's northern end beneath Centennial Park still retains pure water quality.
# Myosin-11

Myosin-11 is a protein that in humans is encoded by the MYH11 gene.

## Function

Myosin-11 is a smooth muscle myosin belonging to the myosin heavy chain family. Myosin-11 is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits.
It is a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP.
Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation.

## Clinical significance

Thoracic aortic aneurysms leading to acute aortic dissections (TAAD) can be inherited in isolation or in association with genetic syndromes, such as Marfan syndrome and Loeys-Dietz syndrome. When TAAD occurs in the absence of syndromic features, it is inherited in an autosomal dominant manner with decreased penetrance and variable expression, the disease is referred to as familial TAAD. Familial TAAD exhibits significant clinical and genetic heterogeneity. Mutations in MYH11 have been described in individuals with TAAD with patent ductus arteriosus (PDA). Of individuals with TAAD, approximately 4% have mutations in TGFBR2, and approximately 1-2% have mutations in either TGFBR1 or MYH11. In addition, FBN1 mutations have also been reported in individuals with TAAD. Mutations within the SMAD3 gene have recently been reported in patients with a syndromic form of aortic aneurysms and dissections with early onset osteoarthritis. SMAD3 mutations are thought to account for approximately 2% of familial TAAD. Additionally, mutations in the ACTA2 gene are thought to account for approximately 10-14% of familial TAAD.

## Acute myeloid leukemia

The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N-terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype.

## Intestinal cancer

MYH11 mutations appear to contribute to human intestinal cancer.
# HMS Newport (1694)

HMS Newport was a member of the standardized 20-gun sixth rates built at the end of the 17th century. She spent her short career sailing between New England and Home Waters. She was captured by French Warships in 1696.
Newport was the first named vessel in the Royal Navy.

## Construction

She was ordered in the First Batch of four ships from Portsmouth Dockyard to be built under the guidance of their Master Shipwright, William Stigant. She was launched on 7 April 1694.

## Commissioned service

Commissioned on 22 January 1694 under the command of Captain Wentworth Paxton, RN, She sailed round trip New England returning to Home waters in 1694, 1695 and 1696. She did not return in 1696.

## Disposition

HMS Newport was captured by French warships in the Bay of Fundy on5 July 1696. She was incorporated into the French Navy as LeNieuport and remained in service until condemned in 1720.

## Citations

* ↑ Winfield
* ↑ Colledge
* ↑ Winfield
* ↑ Winfield
* ↑ Winfield
# Elizabeth Somerset, Countess of Worcester (1546–1621)

Elizabeth Somerset, Countess of Worcester (née Lady Elizabeth Hastings; 1546 – 24 August 1621) was a Scottish-born noblewoman. She was the daughter of Francis Hastings, 2nd Earl of Huntingdon, and Catherine Pole.
On 16 December 1571, at Whitehall Palace, she married Sir Edward Somerset in a triple wedding with Edward de Vere, 17th Earl of Oxford and bride, Anne Cecil, and Edward Sutton, 4th Baron Dudley and bride, Mary Howard, , Sir Edward was the son of son of William Somerset, 3rd Earl of Worcester and Christian North. He succeeded as the 4th Earl of Worcester in 1589.
In 1603, Lady Elizabeth travelled to Berwick upon Tweed with other courtiers in an official party to welcome Anne of Denmark. These were chosen by the Privy Council, following the order of King James of 15 April 1603. The group consisted of two countesses, Frances Howard, Countess of Kildare, Lady Elizabeth, Countess of Worcester; two baronesses Philadelphia, Lady Scrope and Penelope, Lady Rich; and two ladies Anne Herbert, a daughter of Henry Herbert, 2nd Earl of Pembroke, and Audrey Walsingham. A Venetian diplomat, Giovanni Carlo Scaramelli, wrote that the six great ladies were escorted by 200 horsemen. They welcomed the new queen into England on 3 June 1603.

## Children

The Worcesters had fifteen children (eight sons and seven daughters).
* Katherine Somerset (born c. 1575) – 30 October 1624) married William Petre
* William Somerset (born c. 1576)
* Henry Somerset, 1st Marquess of Worcester (born c. 1576 – 18 December 1646) married Anne Russell
* Sir Thomas Somerset, 1st Viscount Somerset (born c. 1578) – died 1650) married Helen Barry
* Robert Somerset (born c. 1580), married Elizabeth Powell, daughter of Sir William Powell.
* Francis Somerset (born c. 1582, Died as an infant)
* Lady Blanche Somerset (born c. 1583 – 28 October 1649) married Thomas Arundell, 2nd Baron Arundell of Wardour
* Sir Charles Somerset (born c. 1584) married Elizabeth Powell
* Margaret Somerset (born c. 1585) married Thomas Windsor, 6th Baron Windsor.
* George Somerset (born c. 1586)
* Edward Somerset (born c. 1588)
* Elizabeth Somerset (born c. 1590) married Sir Henry Guilford
* Anne Somerset married Sir Edward Wynter (c. 1560(?)-1619) of Lydney Glouster on 11 August 1595.
* Frances Somerset (born c. 1596) married William Morgan, 1st baronet of Llantarnam.
* Mary Somerset (born c. 1598)
Lady Elizabeth is buried next to her husband in the Somerset family chapel in the Church of St Cadoc, Raglan, Monmouthshire.

## Ancestry

Ancestors of Elizabeth Somerset, Countess of Worcester (1546–1621) :
# Loldiers of Odin

Loldiers of Odin are a Finnish activist group who dress as clowns, parodying the anti-immigration Soldiers of Odin. The group first appeared on the streets in Tampere in January 2016, dancing and singing alongside a silent march by the Soldiers of Odin.

## Issues

In January 2016, two members were arrested for disrupting a torchlit "Close the Borders" anti-immigration parade. Two of the members have been convicted of petty crime: they have been sentenced to fines for committing nonviolent crimes such as disobedience against police, squats and an unlawful threat against a politician.
# West Nile sub-region

West Nile sub-region, previously known as West Nile Province and West Nile District, is a sub-region in north-western Uganda, in the Northern Region of Uganda.

## Location

The sub-region is bordered by the Democratic Republic of the Congo to the south and west, by South Sudan to the north and by the Albert Nile to the east. The town of Arua, is the largest town in the sub-region. Arua lies approximately 475 kilometres (295 mi), by road, northwest of Kampala, the capital of Uganda, and the largest city in that country.

## Overview

West Nile sub-region consists of the following districts, as of July 1, 2021:
* Adjumani District
* Arua City
* Arua District
* Koboko District
* Maracha District
* Terego District
* Madi-Okollo District
* Moyo District
* Nebbi District
* Yumbe District
* Zombo District
* Obongi District
The sub-region received its name from being located on the western side of the Albert Nile. Military leader and former president of Uganda, Idi Amin, first gained prominence in the West Nile region before staging a military coup and usurping Milton Obote in 1971.

## Energy

As of May 2019, West Nile is supplied by the 3.5-megawatt Nyagak Hydroelectric Power Station, located at Nyapea, Zombo District. This is boosted by the newly installed 4.6-megawatt Yumbe Thermal Power Station, operated by Electromaxx. Another 8-megawatt thermal installation is expected in June 2019.
Meantime, construction of the 6.6-megawatt Nyagak III Hydroelectric Power Station is ongoing, with commissioning expected in 2022. With 16 megawatts to the sub-region now, the current power shortage can be mitigated until the national grid connections arrive in the next two to three years. Electromaxx has received authorization to transfer 12.6 megawatts of its installation at Tororo to West Nile, to alleviate the acute power shortage there.
# Alicia Froling

Alicia Sue Froling (born 31 January 1996) is an Australian professional basketball player.

## Career
### College

Froling plays college basketball at Southern Methodist University in Dallas, Texas for the SMU Mustangs.

### WNBL

Born and raised in Townsville, Froling would begin her WNBL career in her home town, signed as a development player alongside her twin sister, with the Townsville Fire for the 2011–12 WNBL season. Froling remained a member of the Fire's roster through to 2014. She then departed to begin her college career in the United States.
In 2019, Froling was set to return to the league after several years away, signing with the Bendigo Spirit for the 2019–20 season. However, this was soon cut short after an injury and subsequent surgery cancelled her plans for the season.
In August 2020, Froling confirmed she would finally return to the WNBL, set to make her debut with the Bendigo Spirit in the condensed 2020 hub season in her native North Queensland.

## National Team
### Youth Level

Froling first played for Australia at the 2011 FIBA Oceania Under-16 Championship for Women where she took home Gold. She would then go on to participate in the world championship in Amsterdam, Netherlands where Australia placed 5th. Froling would also go on to play for the Gems at two world championships, bringing home a bronze medal on both occasions.

## Personal life

Froling has a twin sister, Keely who is also a professional basketball player. She played alongside her in Townsville, SMU and the U17 National team. Their younger brothers, Harry and Sam, have also represented Australia internationally.
# James Ryan (hurler)

James Ryan (born 7 April 1987) is an Irish hurler who plays as a centre-forward for the Limerick senior teams.
Born in Garryspillane, County Limerick, Ryan arrived on the inter-county scene at the age of eighteen when he first linked up with the Limerick minor hurling team, before later lining out with the under-21 side. He made his senior debut in the 2008 National Hurling League. Ryan has since gone on to play a key part for Limerick, and has won one Munster medal and one National League (Division 2) medal. He was also a regular member of the Limerick Gaelic football team for a number of seasons.
Ryan was named as the Man of the Match in 2013 Munster Senior Hurling Championship Final as Limerick defeated Cork by 0–24 to 0–15 with Ryan scoring three points during the game.
At club level Ryan has won one championship medal with Garryspillane.

## Honours
### Inter-county

* Munster Senior Hurling Championship (1): 2013
# Times Square (Gary Burton album)

Professional ratings :
| Review scores ||
| Source | Rating |
| Allmusic | |
| The Rolling Stone Jazz Record Guide | |
Times Square is an album by vibraphonist Gary Burton recorded in January 1978 and released on ECM November later that year. The quartet features rhythm section Steve Swallow and Roy Haynes, and trumpeter Tiger Okoshi.

## Reception

AllMusic awarded the album four stars, noting that especially Tiger Okoshi's untypical prominent role on the trumpet results in a "fine outing".

## Track listing

* "Semblance" (Keith Jarrett) – 4:01
* "Coral" (Jarrett) – 5:48
* "Peau Douce" (Steve Swallow) – 4:55
* "Careful" (Jim Hall) – 4:42
* "Midnight" (Swallow) – 4:21
* "Radio" (Swallow) – 4:42
* "True Or False" (Swallow, Roy Haynes) – 2:21
* "Como En Vietnam" (Swallow) – 6:43
The track listing on the original release incorrectly swaps tracks "Peau Douce" and "Careful".

## Personnel

* Gary Burton – vibraphone
* Steve Swallow – bass guitar
* Roy Haynes – drums
* Tiger Okoshi – trumpet
# Nayana Wasalathilake

Nayana Wasalathilake is a Sri Lankan businessman and politician who became a member of the Parliament of Sri Lanka from the Badulla District following the resignation of Chaminda Wijesiri. He is a member of the Samagi Jana Balawegaya. In 2023, ahead of the fourth edition of Lanka Premier League, Wasalthilaka acquired the Galle franchise of the league, which was known as Galle Gladiators. The franchise changed its name to Galle Titans under his ownership.
# NPTXR

Neuronal pentraxin receptor is a protein that in humans is encoded by the NPTXR gene.
This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat protein pentraxin is thought to mediate neuronal uptake of synaptic material and the presynaptic snake venom toxin, taipoxin. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for human and mouse, based on strong sequence conservation amongst these species.
# Newman Wright Hoyles

Newman Wright Hoyles (1777–1840) was an English businessman and politician.
Hoyles was born in Dartmouth, England, and he became involved in the Newfoundland fish trade after being a fishing captain for many years. In 1811, he formed a partnership with his brother-in-law and dealt with business along the Southern Shore and Conception Bay.
Hoyles retired from business in 1831 and entered politics in 1832, running for House of Assembly. He was a strong supporter of the local legislature, but difference between him and the reform movement caused Hoyles to become leader of the Conservative faction expressing the interest of the mercantile sector which was disillusioned with the growing power of the Roman Catholic bishop, Michael Anthony Fleming.
Hoyles was appointed Colonial Treasurer in 1833 and kept that position until he died in 1840, even though he never ran for re-election in 1836.
Hoyles son, Hugh W. Hoyles, became the third Premier of Newfoundland Colony.
# Jacques Francœur

Jacques Francœur (1925 – July 24, 2005) was a French-Canadian businessman and journalist. He is best known as the owner of the Unimédia group, making him one of Quebec's media moguls. He was the son of Louis Francœur.

## Biography

He had a long career in publishing, which began at the age of 16 at the daily newspaper La Patrie. He later worked for the Montreal Daily Star and The Gazette. A few years later, he purchased Le Guide du Nord, which marked the beginning of one of the most important media companies in French Canada.
He founded the Dimanche-Matin newspaper. Following that, he partnered with businessman Paul Desmarais for a number of years to establish the Trans-Canada newspaper group. Toward the end of the 1960s, he acquired the weekly newspapers Le Petit Journal, Photo Journal, and La Patrie, which he closed in 1978. In 1973, he founded Unimédia, which would become a publishing conglomerate with a workforce of 2,000 employees and four printing plants. It featured a weekly and two dailies: Le Droit in Ottawa, Le Soleil in Québec City and Le Quotidien in Chicoutimi.
After selling Unimédia to Conrad Black in 1987, he launched one of the most prominent private foundations in Québec, Fondation Jacques Francoeur. This foundation is devoted to funding charities that provide relief for the needy, as well as organizations that promote education. Jacques Francœur also encouraged social and artistic projects for the less fortunate, while granting scholarships for Québec journalists. Furthermore, he was an influential member of many professional and community associations, being a former president of the Newspaper Association of Canada and the Daily Newspaper Association of Québec.
Francœur was also active abroad. He was an executive member of the International Press Institute in London, and from 1982 until 1990 he served on the board of directors of the American Association of Newspaper Editors. In 1995, Francœur was given an honorary degree from Concordia University.
After his death in 1950, he was entombed at the Notre Dame des Neiges Cemetery in Montreal.
# Somasamudra

Somasamudra is a village in the southern state of Karnataka, India. It is located in the Bellary taluk of Bellary district in Karnataka.

## Demographics

As of 2001 India census, Somasamudra had a population of 7107 with 3576 males and 3531 females.