# 2022 Copa Sudamericana

The 2022 Copa CONMEBOL Sudamericana was the 21st edition of the CONMEBOL Sudamericana (also referred to as the Copa Sudamericana), South America's secondary club football tournament organized by CONMEBOL.
On 14 May 2020, CONMEBOL announced the candidate venues for the 2021, 2022 and 2023 club competition finals. On 13 May 2021, CONMEBOL's Council decided that the final would be played at the Estádio Nacional Mané Garrincha in Brasília, Brazil on 1 October 2022. However, on 23 June 2022 the confederation announced that a change of venue was requested by the Brazilian Football Confederation due to the 2022 Brazilian general election taking place one day after the date of the final, and confirmed Estadio Mario Alberto Kempes in Córdoba, Argentina as the new host for the match.
On 25 November 2021, CONMEBOL announced the abolition of the away goals rule in all of its club competitions including the Copa Sudamericana, which had been used since 2005. Accordingly, if in a two-legged tie two teams score the same number of aggregate goals, the winner of the tie would not be decided by the number of away goals scored by each team but by a penalty shoot-out.
Ecuadorian club Independiente del Valle won their second title in the competition after defeating Brazilian side São Paulo by a 2–0 score in the final. As winners of the 2022 Copa Sudamericana, they earned the right to play against the winners of the 2022 Copa Libertadores in the 2023 Recopa Sudamericana and they also automatically qualified for the 2023 Copa Libertadores group stage. Furthermore, in their condition of Copa Sudamericana champions, Independiente del Valle were later invited to play the 2023 UEFA–CONMEBOL Club Challenge against the 2022–23 UEFA Europa League champions. Athletico Paranaense were the previous champions, but did not defend their title since they qualified for the 2022 Copa Libertadores group stage as Copa Sudamericana champions and later advanced to the knockout stage.

## Teams

The following 44 teams from the 10 CONMEBOL associations qualified for the tournament:
* Argentina and Brazil: 6 berths each
* All other associations: 4 berths each
The entry stage is determined as follows:
* Group stage: 12 teams (teams from Argentina and Brazil)
* First stage: 32 teams (teams from all other associations)
| Association | Team (Berth) | Entry stage | Qualification method |
| Argentina (6 berths) | Banfield (Argentina 1) | Group stage | 2020 Copa de la Liga Profesional Copa Sudamericana qualifying play-off winners |
| Argentina (6 berths) | Defensa y Justicia (Argentina 2) | Group stage | 2021 Copa de la Liga Profesional and Primera División aggregate table best team not qualified for 2022 Copa Libertadores |
| Argentina (6 berths) | Independiente (Argentina 3) | Group stage | 2021 Copa de la Liga Profesional and Primera División aggregate table 2nd best team not qualified for 2022 Copa Libertadores |
| Argentina (6 berths) | Lanús (Argentina 4) | Group stage | 2021 Copa de la Liga Profesional and Primera División aggregate table 3rd best team not qualified for 2022 Copa Libertadores |
| Argentina (6 berths) | Racing (Argentina 5) | Group stage | 2021 Copa de la Liga Profesional and Primera División aggregate table 4th best team not qualified for 2022 Copa Libertadores |
| Argentina (6 berths) | Unión (Argentina 6) | Group stage | 2021 Copa de la Liga Profesional and Primera División aggregate table 5th best team not qualified for 2022 Copa Libertadores |
| Bolivia (4 berths) | Royal Pari (Bolivia 1) | First stage | 2021 Primera División 5th place |
| Bolivia (4 berths) | Oriente Petrolero (Bolivia 2) | First stage | 2021 Primera División 6th place |
| Bolivia (4 berths) | Jorge Wilstermann (Bolivia 3) | First stage | 2021 Primera División 7th place |
| Bolivia (4 berths) | Guabirá (Bolivia 4) | First stage | 2021 Primera División 8th place |
| Brazil (6 berths) | Atlético Goianiense (Brazil 1) | Group stage | 2021 Campeonato Brasileiro Série A best team not qualified for 2022 Copa Libertadores |
| Brazil (6 berths) | Santos (Brazil 2) | Group stage | 2021 Campeonato Brasileiro Série A 2nd best team not qualified for 2022 Copa Libertadores |
| Brazil (6 berths) | Ceará (Brazil 3) | Group stage | 2021 Campeonato Brasileiro Série A 3rd best team not qualified for 2022 Copa Libertadores |
| Brazil (6 berths) | Internacional (Brazil 4) | Group stage | 2021 Campeonato Brasileiro Série A 4th best team not qualified for 2022 Copa Libertadores |
| Brazil (6 berths) | São Paulo (Brazil 5) | Group stage | 2021 Campeonato Brasileiro Série A 5th best team not qualified for 2022 Copa Libertadores |
| Brazil (6 berths) | Cuiabá (Brazil 6) | Group stage | 2021 Campeonato Brasileiro Série A 6th best team not qualified for 2022 Copa Libertadores |
| Chile (4 berths) | Unión La Calera (Chile 1) | First stage | 2021 Primera División best team not qualified for 2022 Copa Libertadores |
| Chile (4 berths) | Unión Española (Chile 2) | First stage | 2021 Primera División 2nd best team not qualified for 2022 Copa Libertadores |
| Chile (4 berths) | Deportes Antofagasta (Chile 3) | First stage | 2021 Primera División 3rd best team not qualified for 2022 Copa Libertadores |
| Chile (4 berths) | Ñublense (Chile 4) | First stage | 2021 Primera División 4th best team not qualified for 2022 Copa Libertadores |
| Colombia (4 berths) | Junior (Colombia 1) | First stage | 2021 Primera A aggregate table best team not qualified for 2022 Copa Libertadores |
| Colombia (4 berths) | América de Cali (Colombia 2) | First stage | 2021 Primera A aggregate table 2nd best team not qualified for 2022 Copa Libertadores |
| Colombia (4 berths) | La Equidad (Colombia 3) | First stage | 2021 Primera A aggregate table 3rd best team not qualified for 2022 Copa Libertadores |
| Colombia (4 berths) | Independiente Medellín (Colombia 4) | First stage | 2020 Copa Colombia champions |
| Ecuador (4 berths) | 9 de Octubre (Ecuador 1) | First stage | 2021 Serie A aggregate table best team not qualified for 2022 Copa Libertadores |
| Ecuador (4 berths) | LDU Quito (Ecuador 2) | First stage | 2021 Serie A aggregate table 2nd best team not qualified for 2022 Copa Libertadores |
| Ecuador (4 berths) | Mushuc Runa (Ecuador 3) | First stage | 2021 Serie A aggregate table 3rd best team not qualified for 2022 Copa Libertadores |
| Ecuador (4 berths) | Delfín (Ecuador 4) | First stage | 2021 Serie A aggregate table 4th best team not qualified for 2022 Copa Libertadores |
| Paraguay (4 berths) | Nacional (Paraguay 1) | First stage | 2021 Primera División aggregate table best team not qualified for 2022 Copa Libertadores |
| Paraguay (4 berths) | Guaireña (Paraguay 2) | First stage | 2021 Primera División aggregate table 2nd best team not qualified for 2022 Copa Libertadores |
| Paraguay (4 berths) | Sol de América (Paraguay 3) | First stage | 2021 Copa Paraguay runners-up |
| Paraguay (4 berths) | General Caballero (JLM) (Paraguay 4) | First stage | 2021 División Intermedia champions |
| Peru (4 berths) | Melgar (Peru 1) | First stage | 2021 Liga 1 aggregate table best team not qualified for 2022 Copa Libertadores |
| Peru (4 berths) | Cienciano (Peru 2) | First stage | 2021 Liga 1 aggregate table 2nd best team not qualified for 2022 Copa Libertadores |
| Peru (4 berths) | Sport Boys (Peru 3) | First stage | 2021 Liga 1 aggregate table 3rd best team not qualified for 2022 Copa Libertadores |
| Peru (4 berths) | Ayacucho (Peru 4) | First stage | 2021 Liga 1 aggregate table 4th best team not qualified for 2022 Copa Libertadores |
| Uruguay (4 berths) | Cerro Largo (Uruguay 1) | First stage | 2021 Primera División aggregate table best team not qualified for 2022 Copa Libertadores |
| Uruguay (4 berths) | Montevideo Wanderers (Uruguay 2) | First stage | 2021 Primera División aggregate table 2nd best team not qualified for 2022 Copa Libertadores |
| Uruguay (4 berths) | Liverpool (Uruguay 3) | First stage | 2021 Primera División aggregate table 3rd best team not qualified for 2022 Copa Libertadores |
| Uruguay (4 berths) | River Plate (Uruguay 4) | First stage | 2021 Primera División aggregate table 4th best team not qualified for 2022 Copa Libertadores |
| Venezuela (4 berths) | Deportivo La Guaira (Venezuela 1) | First stage | 2021 Primera División Fase Final A 5th place |
| Venezuela (4 berths) | Estudiantes de Mérida (Venezuela 2) | First stage | 2021 Primera División Fase Final A 6th place |
| Venezuela (4 berths) | Metropolitanos (Venezuela 3) | First stage | 2021 Primera División Fase Final B winners |
| Venezuela (4 berths) | Hermanos Colmenarez (Venezuela 4) | First stage | 2021 Primera División Fase Final B runners-up |

### Notes

* Ecuador (ECU): The 2021 Copa Ecuador was cancelled due to the effects of the COVID-19 pandemic in Ecuador, therefore the Ecuador 4 berth which was originally allocated to the winners of said competition passed over to the 2021 Serie A aggregate table 4th best team not qualified for the 2022 Copa Libertadores.
A further 12 teams eliminated from the 2022 Copa Libertadores were transferred to the Copa Sudamericana, entering the group stage and the round of 16.
| Teams eliminated in third stage | Entry stage |
| Fluminense | Group stage |
| Everton | Group stage |
| Universidad Católica | Group stage |
| Barcelona | Group stage |
| Third-placed teams in group stage | Entry stage |
| Deportivo Táchira | Round of 16 |
| The Strongest | Round of 16 |
| Nacional | Round of 16 |
| Independiente del Valle | Round of 16 |
| Deportivo Cali | Round of 16 |
| Colo-Colo | Round of 16 |
| Olimpia | Round of 16 |
| Universidad Católica | Round of 16 |

## Schedule

The schedule of the competition is as follows:
| Stage | Draw date | First leg | Second leg |
| First stage | 20 December 2021 | 8–10 March 2022 | 15–17 March 2022 |
| Group stage | 25 March 2022 | Matchday 1: 5–7 April 2022Matchday 2: 12–14 April 2022Matchday 3: 26–28 April 2022Matchday 4: 3–5 May 2022Matchday 5: 17–19 May 2022Matchday 6: 24–26 May 2022 | Matchday 1: 5–7 April 2022Matchday 2: 12–14 April 2022Matchday 3: 26–28 April 2022Matchday 4: 3–5 May 2022Matchday 5: 17–19 May 2022Matchday 6: 24–26 May 2022 |
| Round of 16 | 27 May 2022 | 28–30 June 2022 | 5–7 July 2022 |
| Quarter-finals | 27 May 2022 | 2–4 August 2022 | 9–11 August 2022 |
| Semi-finals | 27 May 2022 | 31 August – 1 September 2022 | 7–8 September 2022 |
| Final | 27 May 2022 | 1 October 2022 at Estadio Mario Alberto Kempes, Córdoba | 1 October 2022 at Estadio Mario Alberto Kempes, Córdoba |

## Draws

The draw for the first stage was held on 20 December 2021, 12:00 PYST (UTC−3), at the CONMEBOL Convention Centre in Luque, Paraguay. For the first stage, the 32 teams involved were divided into eight pots according to their national association.
The 32 teams were drawn into 16 ties, with the four teams from each national association being drawn against a rival from the same association in two ties per association and the first team drawn in each tie hosting the second leg.
The draw for the group stage was held on 25 March 2022, 12:00 PYST (UTC−3), at the CONMEBOL Convention Centre in Luque, Paraguay. For the group stage, the 32 teams were drawn into eight groups (Groups A–H) of four containing a team from each of the four pots. Teams from the same association could not be drawn into the same group.
Group stage draw :
| Pot 1 | Pot 2 | Pot 3 | Pot 4 |
| Santos (8) Independiente (10) São Paulo (13) Internacional (17) Racing (19) LDU Quito (20) Lanús (24) Junior (25) | Defensa y Justicia (36) Jorge Wilstermann (39) Independiente Medellín (55) Melgar (66) Montevideo Wanderers (73) Oriente Petrolero (84) Deportivo La Guaira (89) Unión La Calera (91) | River Plate (95) Atlético Goianiense (100) Ceará (107) Banfield (113) Metropolitanos (131) Unión (142) Ayacucho (190) 9 de Octubre (191) | Deportes Antofagasta (197) Guaireña (223) Cuiabá (253) General Caballero (JLM) (No rank) Fluminense (30) Everton (165) Universidad Católica (120) Barcelona (18) |

### Notes

* ^ $^{CLQ3}$ The Copa Libertadores third stage losers were seeded in Pot 4.
The draw for the round of 16 was held on 27 May 2022, 12:00 PYT (UTC−4) at the CONMEBOL Convention Center in Luque, Paraguay. For the round of 16, the 16 teams were drawn into eight ties (A–H) between a Copa Sudamericana group winner (Pot 1) and a Copa Libertadores group third-placed team (Pot 2), with the group winners hosting the second leg. Teams from the same association or the same group could be drawn into the same tie (Regulations Article 2.2.3.2).

## First stage

In the first stage, each tie was played on a home-and-away two-legged basis. If tied on aggregate, extra time was not played, and a penalty shoot-out was used to determine the winner (Regulations Article 2.4.2).
The 16 winners of the first stage advanced to the group stage to join the 12 teams directly qualified for that stage (six from Argentina and six from Brazil), and four teams transferred from the Copa Libertadores (the four teams eliminated in the third stage of qualifying).
| Team 1 | Agg.Tooltip Aggregate score | Team 2 | 1st leg | 2nd leg |
| Jorge Wilstermann | 4–3 | Guabirá | 4–0 | 0–3 |
| Royal Pari | 2–6 | Oriente Petrolero | 2–3 | 0–3 |
| Unión Española | 2–2 (1–4 p) | Deportes Antofagasta | 1–2 | 1–0 |
| Ñublense | 1–2 | Unión La Calera | 0–0 | 1–2 |
| La Equidad | 1–3 | Junior | 0–0 | 1–3 |
| Independiente Medellín | 3–3 (3–1 p) | América de Cali | 2–1 | 1–2 |
| Delfín | 1–3 | 9 de Octubre | 1–1 | 0–2 |
| Mushuc Runa | 1–3 | LDU Quito | 0–2 | 1–1 |
| Nacional | 0–1 | Guaireña | 0–1 | 0–0 |
| Sol de América | 1–5 | General Caballero (JLM) | 0–3 | 1–2 |
| Ayacucho | 4–3 | Sport Boys | 2–0 | 2–3 |
| Cienciano | 1–2 | Melgar | 1–1 | 0–1 |
| Montevideo Wanderers | 3–1 | Cerro Largo | 2–1 | 1–0 |
| Liverpool | 0–3 | River Plate | 0–1 | 0–2 |
| Estudiantes de Mérida | 0–6 | Metropolitanos | 0–2 | 0–4 |
| Hermanos Colmenarez | 2–3 | Deportivo La Guaira | 2–0 | 0–3 |

## Group stage

In the group stage, each group is played on a home-and-away round-robin basis. The teams are ranked according to the following criteria: 1. Points (3 points for a win, 1 point for a draw, and 0 points for a loss); 2. Goal difference; 3. Goals scored; 4. Away goals scored; 5. CONMEBOL ranking (Regulations Article 2.4.2).
The winners of each group advanced to the round of 16 of the final stages.

### Group A

| Pos | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Qualification | LAN | BSC | WAN | MET |
| 1 | Lanús | 6 | 3 | 2 | 1 | 7 | 4 | +3 | 11 | Round of 16 | — | 3–1 | 1–2 | 1–0 |
| 2 | Barcelona | 6 | 2 | 3 | 1 | 9 | 8 | +1 | 9 | | 1–1 | — | 4–2 | 1–0 |
| 3 | Montevideo Wanderers | 6 | 2 | 2 | 2 | 6 | 7 | −1 | 8 | | 0–1 | 0–0 | — | 1–1 |
| 4 | Metropolitanos | 6 | 0 | 3 | 3 | 3 | 6 | −3 | 3 | | 0–0 | 2–2 | 0–1 | — |

### Group B

| Pos | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Qualification | MEL | RAC | CUI | RIV |
| 1 | Melgar | 6 | 4 | 0 | 2 | 10 | 6 | +4 | 12 | Round of 16 | — | 3–1 | 3–1 | 2–0 |
| 2 | Racing | 6 | 4 | 0 | 2 | 7 | 5 | +2 | 12 | | 1–0 | — | 2–0 | 0–1 |
| 3 | Cuiabá | 6 | 2 | 0 | 4 | 7 | 10 | −3 | 6 | | 2–0 | 1–2 | — | 1–2 |
| 4 | River Plate | 6 | 2 | 0 | 4 | 5 | 8 | −3 | 6 | | 1–2 | 0–1 | 1–2 | — |

### Group C

| Pos | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Qualification | SAN | ULC | UCA | BAN |
| 1 | Santos | 6 | 3 | 2 | 1 | 7 | 5 | +2 | 11 | Round of 16 | — | 1–0 | 3–2 | 1–1 |
| 2 | Unión La Calera | 6 | 3 | 2 | 1 | 6 | 4 | +2 | 11 | | 1–1 | — | 3–2 | 1–0 |
| 3 | Universidad Católica | 6 | 1 | 2 | 3 | 7 | 8 | −1 | 5 | | 0–1 | 0–0 | — | 2–0 |
| 4 | Banfield | 6 | 1 | 2 | 3 | 3 | 6 | −3 | 5 | | 1–0 | 0–1 | 1–1 | — |

### Group D

| Pos | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Qualification | SPA | EVE | AYA | WIL |
| 1 | São Paulo | 6 | 5 | 1 | 0 | 12 | 3 | +9 | 16 | Round of 16 | — | 2–0 | 1–0 | 3–0 |
| 2 | Everton | 6 | 3 | 2 | 1 | 7 | 4 | +3 | 11 | | 0–0 | — | 2–1 | 1–1 |
| 3 | Ayacucho | 6 | 1 | 1 | 4 | 5 | 8 | −3 | 4 | | 2–3 | 0–2 | — | 0–0 |
| 4 | Jorge Wilstermann | 6 | 0 | 2 | 4 | 2 | 11 | −9 | 2 | | 1–3 | 0–2 | 0–2 | — |

### Group E

| Pos | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Qualification | INT | GUA | DIM | 9OC |
| 1 | Internacional | 6 | 3 | 3 | 0 | 12 | 5 | +7 | 12 | Round of 16 | — | 1–1 | 2–0 | 5–1 |
| 2 | Guaireña | 6 | 2 | 4 | 0 | 10 | 8 | +2 | 10 | | 1–1 | — | 3–3 | 1–0 |
| 3 | Independiente Medellín | 6 | 1 | 2 | 3 | 8 | 11 | −3 | 5 | | 0–1 | 1–1 | — | 2–1 |
| 4 | 9 de Octubre | 6 | 1 | 1 | 4 | 9 | 15 | −6 | 4 | | 2–2 | 2–3 | 3–2 | — |

### Group F

| Pos | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Qualification | ACG | LDQ | ANT | DYJ |
| 1 | Atlético Goianiense | 6 | 4 | 1 | 1 | 11 | 5 | +6 | 13 | Round of 16 | — | 4–0 | 1–0 | 3–2 |
| 2 | LDU Quito | 6 | 3 | 2 | 1 | 11 | 9 | +2 | 11 | | 1–1 | — | 4–0 | 2–2 |
| 3 | Deportes Antofagasta | 6 | 2 | 0 | 4 | 6 | 11 | −5 | 6 | | 2–1 | 1–2 | — | 1–3 |
| 4 | Defensa y Justicia | 6 | 1 | 1 | 4 | 8 | 11 | −3 | 4 | | 0–1 | 1–2 | 0–2 | — |

### Group G

| Pos | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Qualification | CEA | IND | GCM | DLG |
| 1 | Ceará | 6 | 6 | 0 | 0 | 17 | 1 | +16 | 18 | Round of 16 | — | 2–1 | 6–0 | 3–0 |
| 2 | Independiente | 6 | 4 | 0 | 2 | 13 | 4 | +9 | 12 | | 0–2 | — | 2–0 | 4–0 |
| 3 | General Caballero (JLM) | 6 | 1 | 1 | 4 | 2 | 15 | −13 | 4 | | 0–2 | 0–4 | — | 1–1 |
| 4 | Deportivo La Guaira | 6 | 0 | 1 | 5 | 1 | 13 | −12 | 1 | | 0–2 | 0–2 | 0–1 | — |

### Group H

| Pos | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Qualification | UNI | FLU | JUN | ORI |
| 1 | Unión | 6 | 3 | 3 | 0 | 10 | 2 | +8 | 12 | Round of 16 | — | 0–0 | 1–1 | 2–0 |
| 2 | Fluminense | 6 | 3 | 2 | 1 | 15 | 5 | +10 | 11 | | 0–0 | — | 2–1 | 3–0 |
| 3 | Junior | 6 | 3 | 1 | 2 | 10 | 8 | +2 | 10 | | 0–4 | 3–0 | — | 2–0 |
| 4 | Oriente Petrolero | 6 | 0 | 0 | 6 | 3 | 23 | −20 | 0 | | 1–3 | 1–10 | 1–3 | — |

## Final stages

Starting from the round of 16, the teams play a single-elimination tournament with the following rules:
* In the round of 16, quarter-finals and semi-finals, each tie is played on a home-and-away two-legged basis, with the higher-seeded team hosting the second leg (Regulations Article 2.2.3). If tied on aggregate, extra time will not be played, and a penalty shoot-out will be used to determine the winners (Regulations Article 2.4.4).
* The final is played as a single match at a venue pre-selected by CONMEBOL, with the higher-seeded team designated as the "home" team for administrative purposes (Regulations Article 2.2.6). If tied after regulation, 30 minutes of extra time will be played. If still tied after extra time, a penalty shoot-out will be used to determine the winners (Regulations Article 2.4.5).

### Seeding

Starting from the round of 16, the teams are seeded according to their results in the group stage, with the Copa Sudamericana group winners (Pot 1) seeded 1–8, and the Copa Libertadores group third-placed teams (Pot 2) seeded 9–16.
| Seed | Grp | Teamvte | Pld | W | D | L | GF | GA | GD | Pts | Round of 16 draw |
| 1 | SG | Ceará | 6 | 6 | 0 | 0 | 17 | 1 | +16 | 18 | Pot 1 |
| 2 | SD | São Paulo | 6 | 5 | 1 | 0 | 12 | 3 | +9 | 16 | Pot 1 |
| 3 | SF | Atlético Goianiense | 6 | 4 | 1 | 1 | 11 | 5 | +6 | 13 | Pot 1 |
| 4 | SH | Unión | 6 | 3 | 3 | 0 | 10 | 2 | +8 | 12 | Pot 1 |
| 5 | SE | Internacional | 6 | 3 | 3 | 0 | 12 | 5 | +7 | 12 | Pot 1 |
| 6 | SB | Melgar | 6 | 4 | 0 | 2 | 10 | 6 | +4 | 12 | Pot 1 |
| 7 | SA | Lanús | 6 | 3 | 2 | 1 | 7 | 4 | +3 | 11 | Pot 1 |
| 8 | SC | Santos | 6 | 3 | 2 | 1 | 7 | 5 | +2 | 11 | Pot 1 |
| 9 | LE | Deportivo Cali | 6 | 2 | 2 | 2 | 7 | 4 | +3 | 8 | Pot 2 |
| 10 | LD | Independiente del Valle | 6 | 2 | 2 | 2 | 9 | 7 | +2 | 8 | Pot 2 |
| 11 | LG | Olimpia | 6 | 2 | 2 | 2 | 4 | 4 | 0 | 8 | Pot 2 |
| 12 | LC | Nacional | 6 | 2 | 1 | 3 | 7 | 7 | 0 | 7 | Pot 2 |
| 13 | LF | Colo-Colo | 6 | 2 | 1 | 3 | 9 | 13 | −4 | 7 | Pot 2 |
| 14 | LA | Deportivo Táchira | 6 | 2 | 1 | 3 | 8 | 14 | −6 | 7 | Pot 2 |
| 15 | LB | The Strongest | 6 | 1 | 3 | 2 | 8 | 7 | +1 | 6 | Pot 2 |
| 16 | LH | Universidad Católica | 6 | 1 | 1 | 4 | 5 | 10 | −5 | 4 | Pot 2 |

### Bracket

The bracket was decided based on the round of 16 draw, which was held on 27 May 2022.
| Round of 16 | Round of 16 | Round of 16 | Round of 16 | Round of 16 | Quarter-finals | Quarter-finals | Quarter-finals | Quarter-finals | Quarter-finals | Semi-finals | Semi-finals | Semi-finals | Semi-finals | Semi-finals | | Final (1 October 2022 – Córdoba) | Final (1 October 2022 – Córdoba) | Final (1 October 2022 – Córdoba) | |
| 12 | Nacional | 2 | 2 | 4 | | | | | | | | | | | | | | | |
| 4 | Unión | 0 | 1 | 1 | | | | | | | | | | | | | | | |
| 4 | Unión | 0 | 1 | 1 | 12 | Nacional | 0 | 0 | 0 | | | | | | | | | | |
| | | | | | 3 | Atlético Goianiense | 1 | 3 | 4 | | | | | | | | | | |
| 11 | Olimpia | 2 | 0 | 2 (3) | 3 | Atlético Goianiense | 1 | 3 | 4 | | | | | | | | | | |
| 3 | Atlético Goianiense (p) | 0 | 2 | 2 (5) | | | | | | | | | | | | | | | |
| 3 | Atlético Goianiense (p) | 0 | 2 | 2 (5) | | | | | | 3 | Atlético Goianiense | 3 | 0 | 3 (2) | | | | | |
| | | | | | | | | | | 2 | São Paulo (p) | 1 | 2 | 3 (4) | | | | | |
| 16 | Universidad Católica | 2 | 1 | 3 | | | | | | | | | | | 2 | São Paulo (p) | 1 | 2 | 3 (4) | | | |
| 2 | São Paulo | 4 | 4 | 8 | | | | | | | | | | | | | | | |
| 2 | São Paulo | 4 | 4 | 8 | 2 | São Paulo (p) | 1 | 1 | 2 (4) | | | | | | | | | | |
| | | | | | 1 | Ceará | 0 | 2 | 2 (3) | | | | | | | | | | |
| 15 | The Strongest | 1 | 0 | 1 | 1 | Ceará | 0 | 2 | 2 (3) | | | | | | | | | | |
| 1 | Ceará | 2 | 3 | 5 | | | | | | | | | | | | | | | |
| 1 | Ceará | 2 | 3 | 5 | | | | | | | | | | | | 2 | São Paulo | 0 | |
| | | | | | | | | | | | | | | | | 10 | Independiente del Valle | 2 | |
| 14 | Deportivo Táchira (p) | 1 | 1 | 2 (4) | | | | | | | | | | | | | | | | 10 | Independiente del Valle | 2 |
| 8 | Santos | 1 | 1 | 2 (2) | | | | | | | | | | | | | | | |
| 8 | Santos | 1 | 1 | 2 (2) | 14 | Deportivo Táchira | 0 | 1 | 1 | | | | | | | | | | |
| | | | | | 10 | Independiente del Valle | 1 | 4 | 5 | | | | | | | | | | |
| 10 | Independiente del Valle | 2 | 0 | 2 | 10 | Independiente del Valle | 1 | 4 | 5 | | | | | | | | | | |
| 7 | Lanús | 1 | 0 | 1 | | | | | | | | | | | | | | | |
| 7 | Lanús | 1 | 0 | 1 | | | | | | 10 | Independiente del Valle | 3 | 3 | 6 | | | | | |
| | | | | | | | | | | 6 | Melgar | 0 | 0 | 0 | | | | | |
| 9 | Deportivo Cali | 0 | 1 | 1 | | | | | | | | | | | 6 | Melgar | 0 | 0 | 0 | | | |
| 6 | Melgar | 0 | 2 | 2 | | | | | | | | | | | | | | | |
| 6 | Melgar | 0 | 2 | 2 | 6 | Melgar (p) | 0 | 0 | 0 (3) | | | | | | | | | | |
| | | | | | 5 | Internacional | 0 | 0 | 0 (1) | | | | | | | | | | |
| 13 | Colo-Colo | 2 | 1 | 3 | 5 | Internacional | 0 | 0 | 0 (1) | | | | | | | | | | |
| 5 | Internacional | 0 | 4 | 4 | | | | | | | | | | | | | | | |

### Round of 16

| Team 1 | Agg.Tooltip Aggregate score | Team 2 | 1st leg | 2nd leg |
| Deportivo Táchira | 2–2 (4–2 p) | Santos | 1–1 | 1–1 |
| Nacional | 4–1 | Unión | 2–0 | 2–1 |
| Universidad Católica | 3–8 | São Paulo | 2–4 | 1–4 |
| Colo-Colo | 3–4 | Internacional | 2–0 | 1–4 |
| Deportivo Cali | 1–2 | Melgar | 0–0 | 1–2 |
| The Strongest | 1–5 | Ceará | 1–2 | 0–3 |
| Olimpia | 2–2 (3–5 p) | Atlético Goianiense | 2–0 | 0–2 |
| Independiente del Valle | 2–1 | Lanús | 2–1 | 0–0 |

### Quarter-finals

| Team 1 | Agg.Tooltip Aggregate score | Team 2 | 1st leg | 2nd leg |
| Deportivo Táchira | 1–5 | Independiente del Valle | 0–1 | 1–4 |
| Nacional | 0–4 | Atlético Goianiense | 0–1 | 0–3 |
| São Paulo | 2–2 (4–3 p) | Ceará | 1–0 | 1–2 |
| Melgar | 0–0 (3–1 p) | Internacional | 0–0 | 0–0 |

### Semi-finals

| Team 1 | Agg.Tooltip Aggregate score | Team 2 | 1st leg | 2nd leg |
| Independiente del Valle | 6–0 | Melgar | 3–0 | 3–0 |
| Atlético Goianiense | 3–3 (2–4 p) | São Paulo | 3–1 | 0–2 |

### Final
## Statistics
### Top scorers

| Rank | Player | Team | 1S1 | 1S2 | GS1 | GS2 | GS3 | GS4 | GS5 | GS6 | ⅛F1 | ⅛F2 | QF2 | SF1 | SF2 | F | Total |
| 1 | Bernardo Cuesta | Melgar | 1 | 1 | | 2 | 1 | 1 | | | | 2 | | | | | 8 |
| 2 | Stiven Mendoza | Ceará | | | 1 | | | 1 | 2 | 1 | | | 1 | | | | 6 |
| 3 | Miguel Borja | Junior | | 1 | | 1 | | 1 | 2 | | | | | | | | 5 |
| 3 | Lautaro Díaz | Independiente del Valle | | | | | | | | | | | 1 | 1 | 2 | 1 | 5 |
| 3 | Luciano | São Paulo | | | 1 | | | | | | 2 | 1 | | 1 | | | 5 |
| 3 | Mario Otazú | Guaireña | | | 1 | 1 | | 1 | 2 | | | | | | | | | 5 |
| 7 | Lucas Albertengo | Defensa y Justicia | | | | | 1 | 1 | 2 | | | | | | | | 4 |
| 7 | Alexander Alvarado | LDU Quito | 1 | 1 | | | 2 | | | | | | | | | | | 4 |
| 7 | Mauro Méndez | Montevideo Wanderers | | | 1 | 1 | | 1 | 1 | | | | | | | | | 4 |
| 7 | Sebastián Sáez | Unión La Calera | | 1 | | 1 | | 1 | | 1 | | | | | | | | 4 |
| 7 | Cristian Techera | Ayacucho | | 1 | 1 | 1 | 1 | | | | | | | | | | | 4 |
Source: CONMEBOL