# 2021 World Athletics Relays – Women's 4 × 100 metres relay

The women's 4 × 100 metres relay at the 2021 World Athletics Relays was held at the Silesian Stadium on 1 and 2 May.

## Records

Prior to the competition, the records were as follows:
| World record | United States(Tianna Madison, Allyson Felix, Bianca Knight, Carmelita Jeter) | 40.82 | London, Great Britain | 10 August 2012 |
| Championship record | United States(Tianna Bartoletta, Alexandria Anderson, Jeneba Tarmoh, LaKeisha Lawson) | 41.88 | Nassau, Bahamas | 24 May 2014 |
| World Leading | Star Athletics Louisiana State University | 42.70 | Prairie View, United States Baton Rouge, United States | 3 April 2021 24 April 2021 |

## Results
### Heats

Qualification: First 2 of each heat (Q) plus the 2 fastest times (q) advanced to the final.
* Q Qualified
* q Qualified as fastest times
* WL = World leading
* NR = National record
* SB = Seasonal best
* OG* = 2020 Olympic Games qualification
* WC* = 2022 World Championships qualification
| Rank | Heat | Country | Athletes | Time | Notes |
| 1 | 2 | Netherlands | Jamile Samuel, Dafne Schippers, Nadine Visser, Marije Van Hunenstijn | 43.28 | SB, *OG, *WC |
| 2 | 3 | France | Orlann Ombissa-Dzangue, Cynthia Leduc, Maroussia Paré, Sarah Richard-Mingas | 43.51 | SB, *OG, *WC |
| 3 | 2 | Poland | Paulina Guzowska, Klaudia Adamek, Katarzyna Sokólska, Pia Skrzyszowska | 43.64 | SB, *OG, *WC |
| 4 | 3 | Switzerland | Riccarda Dietsche, Salomé Kora, Cornelia Halbheer, Cynthia Reinle | 43.71 | SB, *WC |
| 5 | 2 | Ecuador | Ángela Tenorio, Anahí Suárez, Virginia Villalba, Marizol Landázuri | 43.86 | NR, *OG, *WC |
| 6 | 1 | Italy | Johanelis Herrera Abreu, Gloria Hooper, Anna Bongiorni, Irene Siragusa | 44.02 | SB, *WC |
| 7 | 1 | Japan | Hanae Aoyama, Mei Kodama, Ami Saito, Remi Tsuruta | 44.17 | SB, *OG, *WC |
| 8 | 3 | Denmark | Mathilde Kramer, Astrid Glenner-Frandsen, Mette Graversgaard, Ida Karstoft | 44.25 | SB, *OG, *WC |
| 9 | 3 | Spain | Maria Isabel Pérez, Estela García, Paula Sevilla, Cristina Lara | 44.38 | SB, *WC |
| 10 | 2 | Ireland | Molly Scott, Sarah Lavin, Kate Doherty, Sarah Quinn | 44.53 | SB, *WC |
| 11 | 2 | Zambia | Suwilanji Theresa Mpondela, Lumeka Katundu, Hellen Makumba, Roda Njobvu | 44.81 | SB |
| 12 | 1 | Ghana | Gemma Acheampong, Latifa Ali, Janet Amponsah, Halutie Hor | 44.85 | SB |
| 13 | 1 | Czech Republic | Johana Kaiserová, Martina Hofmanová, Jana Slaninová, Barbora Šplechtnová | 45.48 | SB |
| | 1 | Brazil | Ana Cláudia Lemos, Vitória Cristina Rosa, Ana Azevedo, Rosângela Santos | DSQ | |

### Final

| Rank | Lane | Nation | Athletes | Time | Notes |
| | 6 | Italy | Irene Siragusa, Gloria Hooper, Anna Bongiorni, Vittoria Fontana | 43.79 | SB |
| | 5 | Poland | Magdalena Stefanowicz, Klaudia Adamek, Katarzyna Sokólska, Pia Skrzyszowska | 44.10 | |
| | 4 | Netherlands | Jamile Samuel, Dafne Schippers, Nadine Visser, Naomi Sedney | 44.10 | |
| 4 | 9 | Japan | Hanae Aoyama, Mei Kodama, Ami Saito, Remi Tsuruta | 44.40 | |
| 5 | 2 | Ecuador | Ángela Tenorio, Anahí Suárez, Yuliana Angulo, Marizol Landázuri | 44.43 | |
| 6 | 3 | Denmark | Mathilde Kramer, Astrid Glenner-Frandsen, Mette Graversgaard, Emma Beiter Bomme | 45.34 | |
| | 7 | France | Wided Atatou, Cynthia Leduc, Maroussia Paré, Sarah Richard Mingas | DNF | |
| | 8 | Switzerland | Riccarda Dietsche, Salomé Kora, Cornelia Halbheer, Cynthia Reinle | DQ | R24.7 |