# 2022 Knoxville Challenger – Singles

Christopher Eubanks was the defending champion but lost in the final to Ben Shelton.
Shelton won the title after defeating Eubanks 6–3, 1–6, 7–6$^{(7–4)}$ in the final.

## Seeds

* Michael Mmoh (semifinals)
* Stefan Kozlov (quarterfinals)
* Christopher Eubanks (final)
* Ben Shelton (champion)
* Emilio Nava (first round)
* Aleksandar Kovacevic (quarterfinals)
* Enzo Couacaud (semifinals)
* Shang Juncheng (first round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| 1 | Michael Mmoh | 7$^7$ | 5 | 2 | | | | | |
| 3 | Christopher Eubanks | 6$^2$ | 7 | 6 | | | | | |
| 3 | Christopher Eubanks | 6$^2$ | 7 | 6 | 3 | Christopher Eubanks | 3 | 6 | 6$^4$ |
| | | | | | 4 | Ben Shelton | 6 | 1 | 7$^7$ |
| 4 | Ben Shelton | 6$^3$ | 6 | 6 | 4 | Ben Shelton | 6 | 1 | 7$^7$ |
| 7 | Enzo Couacaud | 7$^7$ | 4 | 4 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | M Mmoh | 6 | 6 | | | | | | | | | | | | | | | |
| Q | Alexander Bernard | 0 | 0 | | 1 | M Mmoh | 7 | 6 | | | | | | | | | | |
| | U Blanch | 6 | 3 | 7 | | U Blanch | 5 | 3 | | | | | | | | | | |
| Q | Tristan McCormick | 3 | 6 | 5 | | | | | | 1 | M Mmoh | 6 | 6 | | | | | |
| | A Walton | 4 | 6 | 3 | | | | | | | T Sandgren | 3 | 4 | | | | | |
| | Z Svajda | 6 | 4 | 6 | | Z Svajda | 1 | 2 | | | | | | | | | | |
| | T Sandgren | 7$^8$ | 6 | | | T Sandgren | 6 | 6 | | | | | | | | | | |
| 5 | Em Nava | 6$^6$ | 3 | | | | | | | | | | | 1 | M Mmoh | 7$^7$ | 5 | 2 |
| 3 | C Eubanks | 6 | 6 | | | | | | | | | | | 3 | C Eubanks | 6$^2$ | 7 | 6 |
| | N Álvarez Varona | 4 | 2 | | 3 | C Eubanks | 7$^7$ | 6 | | | | | | | | | | |
| Q | S Kirchheimer | 6 | 6 | | Q | S Kirchheimer | 6$^2$ | 4 | | | | | | | | | | |
| WC | Gage Brymer | 3 | 1 | | | | | | | 3 | C Eubanks | 6 | 6 | | | | | |
| | P Jubb | 6 | 3 | 7$^{19}$ | | | | | | | L Gerch | 3 | 2 | | | | | |
| | E Escobedo | 4 | 6 | 6$^{17}$ | | P Jubb | 7 | 6$^2$ | 4 | | | | | | | | | |
| | Lucas Gerch | 6 | 7$^7$ | | | L Gerch | 5 | 7$^7$ | 6 | | | | | | | | | |
| 8 | J Shang | 4 | 6$^3$ | | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | A Kovacevic | 7$^7$ | 4 | 7$^7$ | | | | | | | | | | | | | |
| Alt | E Quinn | 6$^2$ | 6 | 6$^5$ | 6 | A Kovacevic | 6 | 6 | | | | | | | | | |
| | S Fanselow | 6 | 1 | 4 | Q | I Montes de la Torre | 1 | 4 | | | | | | | | | |
| Q | I Montes de la Torre | 3 | 6 | 6 | | | | | 6 | A Kovacevic | 5 | 4 | | | | | |
| Q | G Hussey | 6$^1$ | 1 | | | | | | 4 | B Shelton | 7 | 6 | | | | | |
| | M Krueger | 7$^7$ | 6 | | | M Krueger | 2 | 1 | | | | | | | | | |
| | K Smith | 6 | 4 | 3 | 4 | B Shelton | 6 | 6 | | | | | | | | | |
| 4 | B Shelton | 4 | 6 | 6 | | | | | | | | | 4 | B Shelton | 6$^3$ | 6 | 6 |
| 7 | E Couacaud | 7$^7$ | 6 | | | | | | | | | | 7 | E Couacaud | 7$^7$ | 4 | 4 |
| | Ezekiel Clark | 6$^5$ | 3 | | 7 | E Couacaud | 6 | 6 | | | | | | | | | |
| | A McHugh | 6 | 7$^{10}$ | | | A McHugh | 4 | 2 | | | | | | | | | |
| Q | C Kingsley | 2 | 6$^8$ | | | | | | 7 | E Couacaud | 6 | 7 | | | | | |
| | P Gunneswaran | 6 | 6 | | | | | | 2 | S Kozlov | 3 | 5 | | | | | |
| WC | B Bicknell | 1 | 2 | | | P Gunneswaran | 4 | 3 | | | | | | | | | |
| WC | M Damm | 7$^9$ | 3 | 2 | 2 | S Kozlov | 6 | 6 | | | | | | | | | |
| 2 | S Kozlov | 6$^7$ | 6 | 6 | | | | | | | | | | | | | |