OpenLLM-France/wikimedia huggingface dataset:
# Zymeworks

Zymeworks Inc. is a publicly held biotechnology company based in Vancouver, British Columbia, that develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases. The products are based upon the company's molecular modeling software for optimizing protein structure. In 2014, Zymeworks raised $44 million across various funding rounds according to PitchBook, placing it among the top 10 HealthTech businesses in the world to raise the most capital that year. In May 2017, Zymeworks held an IPO on the Toronto Stock Exchange, raising $59 million. This was the largest Canadian biotech IPO in more than a decade. By alphabetical order, Zymeworks is the last company on the Toronto Stock Exchange.
In May 2019, Zymeworks announced that GSK has expanded its 2016 licensing and collaboration agreement for the research, development and commercialization of bispecific antibodies across multiple disease areas. The extended agreement has meant that GSK can have access to Zymeworks' heavy-light chain pairing technology, which enables the development of bispecific and multifunctional therapeutics.
In September 2019, Zymeworks announced that, following their clinical trials, it has been confirmed that their ZW25 monotherapy can provide durable disease control in patients with a variety of HER2-expressing solid tumors that have progressed following standard of care treatments.
In May 2022, Zymeworks rejected an unsolicited takeover proposal from a Dubai hedge fund, All Blue Falcons FZE, an arm of All Blue Capital.

## Azymetric

This is an IgG1-based heterodimeric antibody scaffold that consists of two different heavy chains engineered to exclusively assemble into a single molecule, allowing bi-specific binding to two different antigens or drug targets. The Azymetric scaffold is engineered by making amino acid changes in the CH3 region of the constant Fc domain of the IgG1. This scaffold can also be engineered with tailored effector function and optimized serum half-life.

## Awards and recognition

* Deal of the Year, Lifesciences BC Awards, 2018
* Life Sciences Company of the Year, Lifesciences BC Awards, 2016
* Emerging company of the year – Health, BIOTECanada Gold Leaf Awards, 2015
* 12th Place, BC's Leading Innovators, 2011
* Life Science Emerging Rocket, 2009, 2010, 2011
* Early stage Company of the year – Industrial & Agriculture, BIOTECanada Gold Leaf Awards, 2009
# Palazzo Loredan a San Cancian

Palazzo Loredan a San Cancian is a palace of the San Cancian branch of the Loredan family located at Calle Larga Widmann in the Cannaregio district of Venice, near the Church of San Canciano after which it was named. The San Cancian branch of the Loredan family produced an illustrious dynasty of admirals and politicians including Pietro Loredan (1372–1438), Alvise Loredan (1393–1466), Giacomo Loredan (1396–1471), Giorgio Loredan (d. 1475), Antonio Loredan (1446–1514), as well as the Duke of Candia Giovanni Loredan (d. 1420).
# Quilon (disambiguation)

Quilon may refer to,
* Venad kingdom, a former state on India's south western Malabar Coast, alternatively known as the State of Quilon
* Kollam, a city in Kerala state, India, formerly Quilon
* Kollam district, in Kerala state, India encompassing the former city of Quilon
* Quilon formation, Geologic formation in India
* Quilon Restaurant, a Michelin starred restaurant in London
# Serravalle

Serravalle (Italian, meaning "place where the valley narrows", and less often meaning "a fortification") may refer to:

## Italy
### Municipalities

* Serravalle a Po, in the province of Mantua
* Serravalle di Chienti, in the province of Macerata
* Serravalle Langhe, in the province of Cuneo
* Serravalle Pistoiese, in the province of Pistoia; the commune also includes the frazioni of Serravalle Scalo and Ponte di Serravalle
* Serravalle Scrivia, in the province of Alessandria
* Serravalle Sesia, in the province of Vercelli
* Castello di Serravalle, a frazione of Valsamoggia in the Metropolitan City of Bologna

### Other places

* Serravalle (Vittorio Veneto), a district of Vittorio Veneto
* Serravalle, a small settlement in the commune of Ala, Trentino
* Serravalle, a small settlement in the commune of Asti, Piedmont
* Serravalle, a small settlement in the commune of Berra, Emilia-Romagna
* Serravalle, a small settlement in the commune of Bibbiena, Tuscany
* Serravalle, Buonconvento, a small settlement in the commune of Buonconvento, Tuscany
* Serravalle, a small settlement in the commune of Filattiera, Tuscany
* Serravalle, a small settlement in the commune of Norcia, Umbria
* Serravalle, a small settlement in the commune of Ortonovo, Liguria
* Serravalle, a small settlement in the commune of Piasco, Piedmont
* Serravalle, a small settlement in the commune of Varano de' Melegari, Emilia-Romagna
* Casali di Serravalle, a small settlement in the commune of Norcia, Umbria
* Serravalle di Carda, a small settlement in the commune of Apecchio, Marche
* Valdara di Serravalle, a small settlement in the commune of Apecchio, Marche
* Castle of Serravalle, a medieval castle in Bosa, Sardinia

## San Marino

* Serravalle, San Marino, a Sammarinese castello

## Switzerland

* Serravalle, Switzerland, a municipality in the canton of Ticino

## People with the surname

* Giovanni da Serravalle (1350–1445), Italian Franciscan and humanist
# 2004 IAAF World Indoor Championships – Women's 60 metres hurdles

The Women's 60 metres hurdles event at the 2004 IAAF World Indoor Championships was held on March 7.

## Medalists

| Gold | Silver | Bronze |
| Perdita Felicien Canada | Gail Devers United States | Linda Ferga-Khodadin France |

## Results
### Heat

First 3 of each heat (Q) and next 4 fastest (q) qualified for the semifinals.
| Rank | Heat | Name | Nationality | Time | Notes |
| 1 | 3 | Gail Devers | United States | 7.88 | Q |
| 2 | 1 | Lacena Golding-Clarke | Jamaica | 7.90 | Q |
| 3 | 1 | Linda Ferga-Khodadin | France | 7.91 | Q, SB |
| 3 | 2 | Perdita Felicien | Canada | 7.91 | Q |
| 3 | 4 | Susanna Kallur | Sweden | 7.91 | Q |
| 6 | 3 | Nicole Ramalalanirina | France | 7.93 | Q, SB |
| 7 | 3 | Carmen Zamfir-Ghilase | Romania | 7.96 | Q, PB |
| 8 | 4 | Delloreen Ennis-London | Jamaica | 8.00 | Q |
| 9 | 1 | Aliuska López | Spain | 8.01 | Q, SB |
| 9 | 2 | Joanna Hayes | United States | 8.01 | Q |
| 11 | 1 | Jenny Kallur | Sweden | 8.02 | q, PB |
| 11 | 4 | Irina Shevchenko | Russia | 8.02 | Q, PB |
| 13 | 1 | Flora Redoumi | Greece | 8.05 | q |
| 13 | 3 | Juliane Sprenger-Afflerbach | Germany | 8.05 | q |
| 13 | 4 | Anay Tejeda | Cuba | 8.05 | q |
| 16 | 2 | Natalia Rusakova | Russia | 8.06 | Q |
| 17 | 3 | Dainelky Pérez | Cuba | 8.08 | |
| 17 | 4 | Glory Alozie | Spain | 8.08 | |
| 19 | 2 | Nadine Faustin-Parker | Haiti | 8.14 | |
| 20 | 4 | Sarah Claxton | Great Britain | 8.15 | |
| 21 | 1 | Angela Whyte | Canada | 8.17 | |
| 22 | 3 | Edit Vári | Hungary | 8.24 | |
| 23 | 2 | Evaggelía Nesoudi | Greece | 8.27 | |
| 23 | 3 | Yauhenia Valadzko | Belarus | 8.27 | |
| 25 | 2 | Lucie Škrobáková | Czech Republic | 8.29 | |

### Semifinals

First 4 of each semifinal (Q) qualified directly for the final.
| Rank | Heat | Name | Nationality | Time | Notes |
| 1 | 1 | Perdita Felicien | Canada | 7.83 | Q, NR |
| 2 | 1 | Joanna Hayes | United States | 7.83 | Q, PB |
| 3 | 1 | Lacena Golding-Clarke | Jamaica | 7.86 | Q, PB |
| 4 | 2 | Gail Devers | United States | 7.88 | Q |
| 5 | 2 | Flora Redoumi | Greece | 7.91 | Q, NR |
| 6 | 2 | Susanna Kallur | Sweden | 7.92 | Q |
| 7 | 2 | Linda Ferga-Khodadin | France | 7.92 | Q |
| 8 | 2 | Delloreen Ennis-London | Jamaica | 7.97 | |
| 9 | 1 | Nicole Ramalalanirina | France | 7.98 | Q |
| 10 | 2 | Natalia Rusakova | Russia | 8.01 | |
| 11 | 2 | Carmen Zamfir-Ghilase | Romania | 8.02 | |
| 12 | 1 | Jenny Kallur | Sweden | 8.03 | |
| 13 | 2 | Juliane Sprenger-Afflerbach | Germany | 8.05 | |
| 14 | 1 | Anay Tejeda | Cuba | 8.18 | |
| 15 | 1 | Irina Shevchenko | Russia | 8.35 | |
| | 1 | Aliuska López | Spain | DNF | |

### Final

| Rank | Lane | Name | Nationality | Time | React | Notes |
| | 5 | Perdita Felicien | Canada | 7.75 | 0.138 | CR, NR |
| | 6 | Gail Devers | United States | 7.78 | 0.128 | |
| | 1 | Linda Ferga-Khodadin | France | 7.82 | 0.172 | =NR |
| 4 | 3 | Joanna Hayes | United States | 7.86 | 0.144 | |
| 5 | 7 | Susanna Kallur | Sweden | 7.89 | 0.168 | |
| 6 | 8 | Lacena Golding-Clarke | Jamaica | 7.89 | 0.151 | |
| 7 | 4 | Flora Redoumi | Greece | 7.94 | 0.188 | |
| 8 | 2 | Nicole Ramalalanirina | France | 8.01 | 0.156 | |
# Morley Currie

Morley Currie (June 23, 1869 – July 11, 1944) was an Ontario physician and political figure. He represented Prince Edward in the Legislative Assembly of Ontario from 1902 to 1908 and in the House of Commons of Canada from 1908 to 1911 as a Liberal member.
He was born in Picton, Ontario, the son of George Currie and Catharine Richards, and studied at the University of Toronto, receiving his M.D. in 1895. Currie served as house surgeon for the Metropolitan Society Lying-in Hospital in New York City, later practicing in Toronto and finally Picton. He married Clara Clarke in 1904. Currie was surgeon and captain in the Prince Edward County militia. He was defeated when he ran for reelection in 1911. Currie died in Picton at the age of 75.

## Electoral record

vte1908 Canadian federal election: Prince Edward :
| Party | Candidate | Votes |
| | Liberal | Morley Currie | 2,341 |
| | Conservative | George Oscar Alcorn | 2,204 |
vte1911 Canadian federal election: Prince Edward :
| Party | Candidate | Votes |
| | Conservative | Bernard Rickart Hepburn | 2,304 |
| | Liberal | Morley Currie | 2,024 |
# 1989 IAAF World Indoor Championships – Men's 1500 metres

The men's 1500 metres event at the 1989 IAAF World Indoor Championships was held at the Budapest Sportcsarnok in Budapest on 4 and 5 March.

## Medalists

| Gold | Silver | Bronze |
| Marcus O'Sullivan Ireland | Hauke Fuhlbrügge East Germany | Jeff Atkinson United States |

## Results
### Heats

First 2 of each heat (Q) and next 4 fastest (q) qualified for the final.
| Rank | Heat | Name | Nationality | Time | Notes |
| 1 | 3 | Hauke Fuhlbrügge | East Germany | 3:42.26 | Q |
| 2 | 3 | Eckhardt Rüter | West Germany | 3:42.65 | Q |
| 3 | 3 | Hervé Phélippeau | France | 3:42.79 | q |
| 4 | 2 | Sergey Afanasyev | Soviet Union | 3:42.83 | Q |
| 5 | 2 | Manuel Pancorbo | Spain | 3:42.84 | Q |
| 5 | 3 | Sydney Maree | United States | 3:42.84 | q |
| 7 | 2 | Radim Kuncický | Czechoslovakia | 3:43.19 | q |
| 8 | 3 | Feranswa Woldemariam | Ethiopia | 3:43.35 | q, NR |
| 9 | 3 | Adelino Hidalgo | Spain | 3:43.95 | |
| 10 | 3 | Róbert Banai | Hungary | 3:43.99 | |
| 11 | 2 | Agberto Guimarães | Brazil | 3:44.86 | |
| 12 | 2 | László Tóth | Hungary | 3:44.99 | |
| 13 | 3 | Dave Reid | Canada | 3:45.87 | |
| 14 | 1 | Marcus O'Sullivan | Ireland | 3:47.34 | Q |
| 15 | 1 | Jeff Atkinson | United States | 3:47.62 | Q |
| 16 | 1 | Mário Silva | Portugal | 3:47.92 | |
| 17 | 1 | Abdelaziz Sahere | Morocco | 3:48.14 | |
| 18 | 2 | Hamid Sajjadi | Iran | 3:48.32 | NR |
| 19 | 1 | Vladimir Kolpakov | Soviet Union | 3:48.33 | |
| 20 | 1 | Mbiganyi Thee | Botswana | 3:48.85 | |
| 21 | 1 | Doug Consiglio | Canada | 3:50.50 | |
| 22 | 1 | Nikolaos Tsiakoulas | Greece | 3:52.05 | |

### Final

| Rank | Name | Nationality | Time | Notes |
| | Marcus O'Sullivan | Ireland | 3:36.64 | CR |
| | Hauke Fuhlbrügge | East Germany | 3:37.80 | NR |
| | Jeff Atkinson | United States | 3:38.12 | AR |
| 4 | Sydney Maree | United States | 3:38.14 | |
| 5 | Hervé Phélippeau | France | 3:38.76 | |
| 6 | Radim Kuncický | Czechoslovakia | 3:39.97 | |
| 7 | Sergey Afanasyev | Soviet Union | 3:40.46 | |
| 8 | Manuel Pancorbo | Spain | 3:41.61 | |
| 9 | Eckhardt Rüter | West Germany | 3:43.42 | |
| 10 | Feranswa Woldemariam | Ethiopia | 3:44.16 | |
# 1,5-anhydro-D-fructose reductase

In enzymology, a 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) is an enzyme that catalyzes the chemical reaction
    1,5-anhydro-D-glucitol + NADP$^+$ $\rightleftharpoons$ 1,5-anhydro-D-fructose + NADPH + H$^+$
Thus, the two substrates of this enzyme are 1,5-anhydro-D-glucitol and NADP$^+$, whereas its 3 products are 1,5-anhydro-D-fructose, NADPH, and H$^+$.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD$^+$ or NADP$^+$ as acceptor. The systematic name of this enzyme class is 1,5-anhydro-D-glucitol:NADP$^+$ oxidoreductase.

## Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2GLX.
# Aelius Theon

Aelius Theon (Ancient Greek: Αἴλιος Θέων, gen.: Θέωνος) was an Alexandrian sophist and author of a collection of preliminary exercises (progymnasmata) for the training of orators. He probably lived and wrote in the mid to late 1st century AD and his treatise is the earliest treatment of these exercises.
The work (extant, though incomplete), which probably formed an appendix to a manual of rhetoric, shows learning and taste, and contains valuable notices on the style and speeches of the masters of Attic oratory. Theon also wrote commentaries on Xenophon, Isocrates and Demosthenes, and treatises on style. He is to be distinguished from the Stoic Theon, who lived in the time of Augustus and also wrote on rhetoric.
# Black ceramics in Lithuania

The tradition of black ceramics goes back to prehistoric times. The oldest articles of black ceramics date back to 6 thousand years BC. They were made in Babylon and Persia, China and Egypt, and later in Greece, Rome and America.
In Lithuania black ceramics were used since the Neolithic Age. During the 1st millennium AD this technique was used to produce anthropomorphic urns and other cult vessels. This technique was very common in the medieval Europe. The Modern Age saw enamel techniques gaining prevalence and black ceramics pushed aside. During the 20th century black ceramics became a rarity. Lithuania is one of the few locations in the world where these ceramics have been preserved.
# Keith English (end)

Keith English (born February 13, 1927 – January 21, 2019) was a Grey Cup champion and award-winning Canadian Football League player. He was primarily an offensive end but also played on defence.
A graduate of both Loyola High School and Loyola College, English joined his hometown Montreal Alouettes in 1948. Playing 12 regular season games he scored 2 touchdowns and a safety, good enough to win the Gruen Trophy for best rookie in the eastern Big Four (at a time when only Canadians could win the award). In 1949 he was an integral part of the Larks first Grey Cup championship. He retired after only 4 seasons with Montreal, playing 39 games.
He later became an avid curler and golfer, and was a Vice-President with McFarlane Son and Hodgson Ltd. In 1972 he was elected into the Loyola College Sports Hall of Fame (now Concordia University). He died on January 21, 1989, aged 61, from undisclosed causes.
# Tennessee Rats

The Tennessee Rats was a small club of Black baseball players formed in Holden, Missouri running from approximately 1910 to 1926.

## History

Run by W.A. Brown, the Tennessee Rats was almost purely a traveling team, and toured much of Iowa and other surrounding states, playing baseball and in the early years, producing a minstrel show to add to the box office take after the baseball games.
Many researchers do not consider the Tennessee Rats a "formal" Negro league team. However, like other barnstorming teams of the time, they had considerable impact on the desegregation of baseball. Today, the Tennessee Rats are rarely mentioned in Black baseball history, and stats and rosters are hard to find.

## Notable players

* John Donaldson
* Jack Marshall
# Van Buren County Courthouse (Michigan)

The Van Buren County Courthouse is a government building located at 212 East Paw Paw Street in Paw Paw, Michigan. It was designated a Michigan State Historic Site in 1977 and listed on the National Register of Historic Places in 1979.

## History

Van Buren County was originally platted in 1829, and in 1837, the Board of Supervisors chose Paw Paw as the county seat. Construction began on this site in 1842, and the building was occupied in 1845. In 1900, it was decided to construct a new courthouse for the county, and a bond issue of $35,000 was approved by voters for the purpose. The older courthouse was moved to accommodate a new structure; the original Van Buren County Courthouse now serves as the Paw Paw City Hall.
The county hired Jackson architect Claire Allen to design the building, and contractor George Rickman & Sons to construct it. The cornerstone was laid on September 2, 1901, and the total cost, including courthouse, jail, and furnishings, was $120,000. Construction took a year and a half, and the building was dedicated on February 23, 1903.
In 1974, an annex was added to the courthouse to open up more office space. A memorial clock, designated the Sheldon and Oradell Rupert Memorial Clock, was installed in the tower in 1986.

## Description

The Van Buren County Courthouse is a three-story rectangular Classical Revival structure constructed of yellow sandstone with a red tile hip roof. An Italian Renaissance clock tower topped with a cupola is placed in the center of the building. The cupola and the main cornice are both constructed of copper.
The interior of the courthouse is substantially original. The courtroom has high curved ceilings and dark woodwork, as well as electric chandeliers built to look like the original gas fixtures. Four large murals are also in the courthouse.
# Linia

Here are places that have the name Linia:

## In Africa

* Linia, Chad

## In Europe

* Linia, Corfu, Greece
* Linia, Pomeranian Voivodeship (north Poland)
* Linia, a village in Budeşti Commune, Vâlcea County, Romania
* Linia, a village in Grădiştea Commune, Vâlcea County, Romania
# 1892 Mercer Baptists football team

The 1892 Mercer Baptists football team represented Mercer University in the 1892 college football season. They finished with a record of 1–0, securing their first win in program history with a score of 12–6 in their only game.

## Schedule

| Date | Opponent | Site | Result |
| November 5 | Georgia Tech | Central City ParkMacon, GA | W 12–6 |
# Qoli Beyglu, Ardabil

Qoli Beyglu (Persian: قلي بيگلو, also Romanized as Qolī Beyglū) is a village in Arshaq-e Markazi Rural District, Arshaq District, Meshgin Shahr County, Ardabil Province, Iran. At the 2006 census, its population was 162, in 37 families.
# Rječica Donja

Rječica Donja (Serbian: Рјечица Доња) is a village in the municipality of Doboj, Republika Srpska, Bosnia and Herzegovina.
# Ko Kha subdistrict

Ko Kha (Thai: เกาะคา) is a village and tambon (subdistrict) of Ko Kha District, in Lampang Province, Thailand. In 2005 it had a total population of 4352 people. The tambon contains 8 villages.
# University of New Mexico–Los Alamos

The University of New Mexico–Los Alamos (UNM-LA) in Los Alamos, New Mexico, is a branch campus of the University of New Mexico. UNM-LA offers 14 certificate programs and 18 associate degree programs. In addition, UNM-LA offers a Dual Credit program, which allows high school students to take college classes; an adult basic education program for students seeking their New Mexico High School Equivalency Credential (the General Education Development (GED) or HiSet); and an ESL (English as a Second Language) program. Students often work part-time at Los Alamos National Laboratory.

## Campus

UNM-LA is located in central Los Alamos.
* The east entrance to campus
* The campus from Sullivan Field
* Library tower
# Ko Kham

Ko Kham (Thai: เกาะขาม, pronounced) is a small island near Ko Mak, in Trat Province, Thailand.
* Bungalows on the island
# Qoliabad, Kurdistan

Qoliabad (Persian: قلي آباد, also Romanized as Qolīābād) is a village in Nanur Rural District, Nanur District, Baneh County, Kurdistan Province, Iran. At the 2006 census, its population was 95, in 16 families. The village is populated by Kurds.
# Ko Lan

Ko Lan (Thai: เกาะล้าน, pronounced) is one of the eastern seaboard islands of Thailand. Ko Lan lies 7.5 km from the nearest shore, Pattaya. "Ko Lan" is the name of the island in the Royal Thai General System of Transcription. It is also known as "Koh Larn" and "Ko Laan".

## Geography

About four kilometres long and two kilometres wide occupying 3,411 rai, Ko Lan is the largest of the "near islands" off south Pattaya, at the southeast end of the Bay of Bangkok, and on the east side of the Gulf of Siam. Administratively Ko Lan belongs to the Amphoe Bang Lamung, Chonburi Province.
It is an island of hills covered with low tropical forest. A Buddhist shrine is located at its highest point, 180 metres above sea level. The island has two small villages, Ban Ko Lan and Ban Krok Makhan, where there are lodgings and restaurants. Ferries connect Ko Lan to the mainland.
Most of Ko Lan's eight beaches are on its west side. Most visited is Tawaen Beach, where there is a small harbor. The beach is lined with small tourist shops and restaurants. Other beaches include Tonglang Beach, Tien Beach, Samae Beach, Tayaiy Beach, and Nual Beach.
Ko Lan has 1,567 hotel and resort rooms and two wharves.
* Lan Island
* Ko Lan from the east
* Sunset, Ko Lan
* Tawaen Beach

## Recreation

The "Koh Larn Classic" is a sailing and running race event held at the nearby Royal Varuna Yacht Club in Pattaya. Since 2023, the Koh Larn Trail Run has taken place in February and has participants run either an 11-kilometer or 25-kilometer route around the island's trails.

## Adjacent islands

Two smaller islands are near Ko Lan:
* Ko Sak (เกาะสาก), a narrow "c"-shaped island with a small bay open towards the north. It is 0.6 km off Ko Lan's northern tip. Its highest point is 33 m. It has a horseshoe-shaped beach in the north. Accommodation is available.
* Ko Krok (เกาะครก), a private island less than two kilometres to the east of Ko Lan's northeast shore. Its highest point is 41 m.
Ko Phai, the main island of Mu Ko Phai (หมู่เกาะไผ่), the group of "far islands", off Pattaya is about 14 km to the west of Ko Lan.

## Impact of mass tourism

During low season, Ko Lan attracts about 3,000 visitors a day. In high season, as many as 10,000 people daily visit. They generate about two million baht in daily income. Its maximum daily visitor capacity is 6,410. In addition, there are up to 8,000 permanent residents and workers on the island. Visitors and island residents generate about 50 tonnes of solid waste per day, mostly waste from food and plastic containers, foam and glass bottles, but Pattaya City authorities are only able to remove 20–25 tonnes per day. Pattaya City has no landfill of its own. It transports all of its waste and that of Ko Lan to a site in neighbouring Saraburi. The remaining daily 10 tonnes of refuse on Ko Lan is building up at a 12 rai sized dump site in the island's centre. There are over 50,000 tonnes of accumulated rubbish on the island. Plans existed to build a garbage recycling and separation plant by 2016. It has not happened.