# List of number-one dance airplay hits of 2008 (U.S.)

These are the Billboard magazine Hot Dance Airplay number one hits of 2008. (Note: Billboard publishes charts with an issue date approximately 7–10 days in advance).
| † | Number-one dance airplay song of the year |
| Issue date | Song | Artist(s) | Remixer(s) |
| January 5 | "Amazing" | Seal | Kaskade; Jacques Lu Cont |
| January 12 | "In My Arms" | Plumb | Bimbo Jones |
| January 19 | "In My Arms" | Plumb | Bimbo Jones |
| January 26 | "Calabria 2007" | Enur featuring Natasja | Original |
| February 2 | "What Hurts the Most" | Cascada | Original; Spencer & Hill |
| February 9 | "Let Me Think About It" | Ida Corr | Fedde le Grand |
| February 16 | "Anthem" | Filo & Peri featuring Eric Lumiere | Original |
| February 23 | "Let Me Think About It" | Ida Corr vs. Fedde LeGrande | |
| March 1 | "Let Me Think About It" | Ida Corr vs. Fedde LeGrande | |
| March 8 | "Let Me Think About It" | Ida Corr vs. Fedde LeGrande | |
| March 15 | "Let Me Think About It" | Ida Corr vs. Fedde LeGrande | |
| March 22 | "Let Me Think About It" | Ida Corr vs. Fedde LeGrande | |
| March 29 | "Stars" | Erika Jayne | Moto Blanco |
| April 5 | "I Can't Help Myself" | Bellatrax featuring Sophia May | Sunfreakz |
| April 12 | "I Can't Help Myself" | Bellatrax featuring Sophia May | Sunfreakz |
| April 19 | "I Can't Help Myself" | Bellatrax featuring Sophia May | Sunfreakz |
| April 26 | "Now You're Gone" | Basshunter featuring DJ Mental Theo's Bazzheads | Fonzerelli |
| May 3 | "Now You're Gone" | Basshunter featuring DJ Mental Theo's Bazzheads | Fonzerelli |
| May 10 | "Bleeding Love" | Leona Lewis | Jason Nevins; Kings of Soul; Moto Blanco; Shapeshifters |
| May 17 | "Bleeding Love" | Leona Lewis | Jason Nevins; Kings of Soul; Moto Blanco; Shapeshifters |
| May 24 | "Bleeding Love" | Leona Lewis | Jason Nevins; Kings of Soul; Moto Blanco; Shapeshifters |
| May 31 | "Bleeding Love" | Leona Lewis | Jason Nevins; Kings of Soul; Moto Blanco; Shapeshifters |
| June 7 | "4 Minutes" | Madonna featuring Justin Timberlake | Bob Sinclar; Junkie XL; Peter Rauhofer |
| June 14 | "Pocketful of Sunshine" | Natasha Bedingfield | Johnny Vicious; StoneBridge |
| June 21 | "Pocketful of Sunshine" | Natasha Bedingfield | Johnny Vicious; StoneBridge |
| June 28 | "Bleeding Love" | Leona Lewis | |
| July 5 | "Pocketful of Sunshine" | Natasha Bedingfield | |
| July 12 | "Give It 2 Me" | Madonna | Fedde le Grand; Paul Oakenfold; Jody den Broeder; Tong & Spoon; Eddie Amador; Bongo Joe |
| July 19 | "We Break the Dawn" | Michelle Williams featuring Flo Rida | Mr. Mig; Maurice Joshua |
| July 26 | "I Kissed a Girl" | Katy Perry | Jason Nevins; Dr. Luke; DJ Cobra & Jess Jackson |
| August 2 | "I Kissed a Girl" | Katy Perry | Jason Nevins; Dr. Luke; DJ Cobra & Jess Jackson |
| August 9 | "I Kissed a Girl" | Katy Perry | Jason Nevins; Dr. Luke; DJ Cobra & Jess Jackson |
| August 16 | "I Kissed a Girl" | Katy Perry | Jason Nevins; Dr. Luke; DJ Cobra & Jess Jackson |
| August 23 | "I Kissed a Girl" | Katy Perry | Jason Nevins; Dr. Luke; DJ Cobra & Jess Jackson |
| August 30 | "Closer" | Ne-Yo | Stonebridge, Norty Cotto |
| September 6 | "Move for Me" | Kaskade and Deadmau5 | Santiago & Bushido, Rasmus Faber, Mind Electric |
| September 13 | "Disturbia" | Rihanna | Jody Den Broeder, Craig C, Nique |
| September 20 | "Disturbia" | Rihanna | Jody Den Broeder, Craig C, Nique |
| September 27 | "Disturbia" | Rihanna | Jody Den Broeder, Craig C, Nique |
| October 4 | "Disturbia" | Rihanna | Jody Den Broeder, Craig C, Nique |
| October 11 | "Disturbia" | Rihanna | Jody Den Broeder, Craig C, Nique |
| October 18 | "Disturbia" | Rihanna | Jody Den Broeder, Craig C, Nique |
| October 25 | "You Make Me Feel" | Annagrace | Bernd Augustinski, Francesco Diaz & Thomas Gold, VooDoo & Serano, John Luniz |
| November 1 | "Move for Me" | Kaskade and Deadmau5 | |
| November 8 | "Every Word" | Ercola and Daniella | Wendel Kos |
| November 15 | "Every Word" | Ercola and Daniella | Wendel Kos |
| November 22 | "Feel Your Love" | Kim Sozzi | |
| December 6 | "So What" | Pink | Bimbo Jones |
| December 13 | "Behind" | Flanders | Bimbo Jones, Callea |
| December 20 | "Behind" | Flanders | Bimbo Jones, Callea |
| December 27 | "Miles Away" | Madonna | Thin White Duke, Morgan Page, Johnny Vicious, Rebirth, Aaron LaCrate & Samir B-More |