OpenLLM-France/wikimedia huggingface dataset:
# Turiaçu River

The Turiaçu River is a river of Maranhão state in northeastern Brazil.
# Mensacarcin

Mensacarcin is a highly oxygenated polyketide first isolated from soil-dwelling Streptomyces bottropensis bacteria.
The molecule is a secondary metabolite, and can be obtained in large amounts from its producing organism.
Due to its unique properties it is an important model for drug development against melanoma and other cancers.

## Medical properties

In NCI-60 anti-cancer compound screening mensacarcin has a high cytostatic effect against almost all cell lines (mean of 50% growth inhibition) and a relatively selective cytotoxic effect against melanoma cells.
Low COMPARE correlation with standard antitumor agents indicate a unique mechanism of action. Further examinations reveal mensacarcin effecting the mitochondria.

### Potential use in cancer therapy

With its unique mechanism, effective also in BRAF V600E mutation cell lines, mensacarcin is a promising model for the development of new anticancer drugs.
Existing therapies for melanoma are limited. Mensacarcin's powerful effect against melanoma cells make it especially valuable for this disease.

## Mechanism of action
### Specific disruption of mitochondrial function

Mitochondria provide most of the energy used by eukaryotic cells.
In a study at the Oregon State University a synthesized fluorescent probe of mensacarcin was localized to the mitochondria within 20 minutes of treatment.
Live-cell bioenergetic flux analysis showed rapid disturbance of energy production and of mitochondrial function.
The localization together with the metabolic effects provide evidence that mensacarcin targets mitochondria.

### Induction of cell death

Mitochondria are also important in cell death signaling.
Mensacarcin in melanoma cells activates apoptotic pathways related to caspase 3 and caspase 7, and thus induces cell death.
After mensacarcin treatment of two melanoma cell lines, the cells showed characteristic chromatin condensation as well as distinct poly(ADP-ribose)polymerase-1 cleavage; flow cytometry identified a large population of apoptotic cells; single-cell electrophoresis indicated that mensacarcin causes genetic instability, a sign of early apoptosis.

### Effect in melanoma cell lines with BRAF V600E mutation

The BRAF V600E mutation is associated with drug resistance. Due to its independent mechanism, mensacarcin has an undiminished effect in melanoma cell lines with this mutation (NCI 60 cell lines SK-Mel-28 and SK-Mel-5).
# Pintharuka, Western Australia

Pintharuka is an abandoned townsite in the Mid West region of Western Australia. The town is located between the towns of Morawa and Mullewa on the Mullewa-Wubin Road
During the planning of the railway to be constructed between Mullewa and Wongan Hills in 1912, the local progress association requested that a townsite be surveyed at the siding that was to be built in the present townsite. The name of the siding was chosen as Pintharika in 1913 and the townsite was gazetted later the same year.
The area's main industry is in agriculture: particularly cereal cropping and raising livestock. The town and the area was flooded and many sheep were killed in 1948 by the hail and rain from violent thunderstorms.
The name of the town is taken from a nearby well which was surveyed and recorded in 1910. The name is Aboriginal in origin but its meaning is not known.
In 1932, the Wheat Pool of Western Australia announced that the town would have two grain elevators, each fitted with an engine installed at the railway siding.
The town is a receival site for Cooperative Bulk Handling.
# Oliver Huie

Oliver Jones Huie (September 9, 1878 – December 22, 1951) was an American college football player and coach. He served as the head coach for Georgia Tech in 1903.
Huie was born in Clayton County, Georgia. He attended Georgia School of Technology (later Georgia Institute of Technology) and played on the football team in 1901. He later attended Davidson College (later University). After graduation, Huie worked for the Southern Bell Telephone and Telegraph Company. On July 20, 1903, he was selected by Georgia Tech's athletic association to coach the football team for the 1903 Georgia Tech season. Under Huie, the team registered only its second multi-win season since 1893. Georgia Tech finished 3–5. Huie did not return to coach the following year as Georgia Tech hired John Heisman.
Huie continued to work for Southern Bell at least through World War I. He died in Atlanta, Georgia on December 24, 1951.

## Head coaching record

| Year | Team | Overall | Conference | Standing |
| Georgia Tech (Southern Intercollegiate Athletic Association) (1903) ||||||
| 1903 | Georgia Tech | 3–5 | 1–4 | 13th |
| Georgia Tech: | Georgia Tech: | 3–5 | 1–4 | |
| Total: | Total: | 3–5 | | |
# Udhanwal

Udhanwal is a village in Batala in Gurdaspur district of Majha Punjab state, India. Udhanwal is re-setup on the "THAE" by a Sikh sardar of Kalsi caste and he was also Ramgharia Risaldar in Sikh Khalsa Army of Maharaja Ranjeet Singh. Prior he was the resident of village Dhandoi near Batala. He re-setup his own new village Udhanwal along with another forty families of Sikh faith specially Kalsi peoples from the nearby villages of the Majha belt of panjab just before the death of Sher-e-panjab Maharaja Ranjeet Singh. It is located 21 kilometres (13 mi) from sub district headquarters, 45 kilometres (28 mi) from district headquarters and 12 kilometres (7.5 mi) from Sri Hargobindpur. The village is administrated by Sarpanch an elected representative of the village.

## Demography

As of 2011, the village had 368 houses and a population of 2088 of which 1069 were males while 1019 were females. According to the report published by Census India in 2011, 829 are from Schedule Caste and the village has no Schedule Tribe population.
# Saint-Astier

Saint-Astier may refer to the following places in France:
* Saint-Astier, Dordogne, a commune in the Dordogne department
* Saint-Astier, Lot-et-Garonne, a commune in the Lot-et-Garonne department
# WASP-14b

WASP-14b is an extrasolar planet discovered in 2008 by SuperWASP using the transit method. Follow-up radial velocity measurements showed that the mass of WASP-14b is almost eight times larger than that of Jupiter. The radius found by the transit observations show that it has a radius 25% larger than Jupiter. This makes WASP-14b one of the densest exoplanets known. Its radius best fits the model of Jonathan Fortney.

## Orbit

First calculation of WASP-14b's Rossiter–McLaughlin effect and so spin-orbit angle was −14 ± 17 degrees. It is too eccentric for its age and so is possibly pulled into its orbit by another planet. The study in 2012 has updated spin-orbit angle to 33.1±7.4°.
# Sulimov

Sulimov is a municipality and village in Kroměříž District in the Zlín Region of the Czech Republic. It has about 200 inhabitants.

## History

The first written mention of Sulimov is from 1353.
# Triangle Country Club Ground

Triangle Country Club is a cricket ground in Triangle, Masvingo, Zimbabwe attached to a larger sporting complex. The first major recorded match was a first-class fixture between Zimbabwe-Rhodesia B and Border in the 1979/80 Castle Bowl, which ended in a draw. For the next thirty-four years the ground held no further major matches, until 2013 when the Southern Rocks were due to play the Mountaineers in a List A match in the 2012/13 Zimbabwe Domestic One-Day Competition, however this match was abandoned. In that same season the Southern Rocks were also due to play a single Twenty20 match there in the Domestic Twenty20 Competition, however this match too was abandoned.
# Merari

According to the Torah, Merari (Hebrew: מְרָרִי, Mərārī) was one of the sons of Levi, and the patriarchal founder of the Merarites, one of the four main divisions among the Levites in Biblical times. The Hebrew word Merari means sad, bitter or strong (in the sense that a dish with a bitter taste might be said to have a "strong" taste). The Merarites were charged with the transportation and care of the structural components of the tabernacle.
Richard Elliott Friedman attributes the genealogy to the Book of Generations, a document originating from a similar religiopolitical group and date to the priestly source. According to some biblical scholars, the Torah's genealogy for Levi's descendants is actually an aetiological myth reflecting the fact that there were four different groups among the levites - the Gershonites, Kohathites, Merarites, and Aaronids; according to the Jewish Encyclopedia, Levite was originally just a job title, deriving from the Minaean word lawi'u meaning priest, rather than having been the name of a tribe.
# Pintesfeld

Pintesfeld is a municipality in the district of Bitburg-Prüm, in Rhineland-Palatinate, western Germany.
# Olszyny

Olszyny may refer to:
* Olszyny, Lower Silesian Voivodeship (south-west Poland)
* Olszyny, Podlaskie Voivodeship (north-east Poland)
* Olszyny, Łódź Voivodeship (central Poland)
* Olszyny, Chrzanów County in Lesser Poland Voivodeship (south Poland)
* Olszyny, Gmina Rzepiennik Strzyżewski in Lesser Poland Voivodeship (south Poland)
* Olszyny, Gmina Wojnicz in Lesser Poland Voivodeship (south Poland)
* Olszyny, Masovian Voivodeship (east-central Poland)
* Olszyny, Pomeranian Voivodeship (north Poland)
* Olszyny, Warmian-Masurian Voivodeship (north Poland)
# Uganda at the 2000 Summer Paralympics

Uganda sent a delegation to compete at the 2000 Summer Paralympics in Sydney, Australia. The country entered only one athlete, who competed in swimming. She did not win a medal.

## Swimming

Prossy Tusabe, Uganda's only representative, competed in the women's 100m freestyle (S10 category). She finished last in her heat, her time of 2:12.45 far behind that of the second slowest overall (the United States's Karen Noris, in 1:09.37). Thus she did not advance to the final.
# Trang Nguyen

Trang Nguyen or Nguyên Thị Thu Trang (born March 2, 1990) is a Vietnamese wildlife conservationist, environmental activist and a writer. She is known for her conservation works in tackling the illegal wildlife trade in Africa and Asia. In Vietnam, she is well known for her book Tro Ve Noi Hoang Da (Back to the Wilderness) and Chang hoang da - Gau (Chang is Wild about Bears). In 2018, at the age of 28, she received an award from Future for Nature, as well as Eco-Warrior from Elle Style Awards. She was also voted as 30 under 30 by Forbes Vietnam and nominated for the Women of the Future - Southeast Asian region 2018 for her contribution in global wildlife conservation. She was also included in the list of global most influential women by the BBC in 2019 and 30 Under 30 Forbes Asia in 2020.
In 2013, Trang was immortalised as an online game character to help raise awareness on rhino conservation. The game attracted over 3 million players within the first two weeks of game launched. In 2018, Trang Nguyen participated in the South African documentary film, Stroop: Journey into the Rhino Horn War. and the US documentary Breaking Their Silence: Women on the Frontline of the Poaching War. In 2023, Nguyen was featured in BBC documentary series Planet Earth III while going undercover to prevent illegal ivory trade in Ivory Coast.
# Kurt Harald Isenstein

Kurt Harald Isenstein (13 August 1898 – 3 February 1980) was a German sculptor. His work was part of the sculpture event in the art competition at the 1928 Summer Olympics.
# Roland (bishop of Treviso)

Roland of Parma was an Italian cleric during the Investiture Controversy. He took the side of the Holy Roman Empire and served as the bishop of Treviso from 1073/1078 until 1089/1096.
Roland came from the upper ranks of the clergy of Parma. In a charter of 1073, Bertha, abbess of San Paolo in Parma, donated property she owned in Berceto to her convent. The act was witnessed by Roland, described as deacon, provost and scholaster (diaconus et praepositus et magister scholarum). He signed immediately after the bishop, Everard, and the archpriest, Gezzo, indicating his position in the ecclesiastical hierarchy of Parma at that time.
Roland probably became bishop around 1077. His predecessor as bishop, Accelinus, is last attested on 2 January 1073. Roland was appointed bishop of Treviso by the King Henry IV sometime between 1073 and 1078. Both Bonizo of Sutri in his Liber ad amicum and Donizo in his Vita Mathildis refer to him simply as "the cleric Roland", Rolandus clericus, when discussing the episode of 1076.
In February 1076, Roland delivered the decisions of the German council of Worms and the Italian council of Piacenza—demanding the pope's abdication—to Pope Gregory VII in Rome. Although Roland had not attended Worms, he was present at Piacenza. He travelled with one of the king's servants, unnamed in contemporary accounts. Roland arrived in Rome just before the Lenten synod (14–22 February), and Gregory had the letter from Henry IV read out at the first session. According to the account of Bonizo, Roland so enraged the assembly that Gregory had to intervene to save his life and end the session. The empress dowager Agnes of Poitou, in a letter to Bishop Altmann of Passau, described the scene as an eyewitness: "the envoys of my son the king came into the synod and, in the presence of all, they told the pope, on my son's behalf, that he should rise and renounce the apostolic see, which he had acquired not canonically but by robbery. They were at once seized by the Romans."
The official record of the Lenten synod of 1078, held from 27 February until 3 March, says that Roland, "who to acquire the honor of a bishop became a crafty ambassador, did not recoil from making a schism between the kingdom and the priesthood", and records his excommunication and deposition. The Lenten synods of 1079 and 1080 repeated the decree of excommunication. Roland is still attested as a canon of the cathedral of Parma in charge of the school in 1080, but by 1081 he had been replaced in this position by Ingo.
On 25 June 1080, Roland signed the decree of the council of Brixen against Gregory VII, adding beside his name the word libentissime, "freely". He is attested as an intervener for Aquileia in a charter of 1081. He attended the synod held by the anti-pope Clement III in Ravenna in 1086. His last appearance is in the record of a placitum held in Treviso on 13 October 1089 by Duke Liutold of Carinthia, who was also Margrave of Verona. His successor as bishop, Gumpold, is mentioned for the first time in the latter half of 1096.
# Snowden Hall (Laurel, Maryland)

Snowden Hall is a historic house located on the grounds of the Patuxent Wildlife Research Center, outside Laurel in Prince George's County, Maryland, United States. It stands on open rolling ground approximately 3⁄4-mile west of the Patuxent River.

## History

Snowden Hall is a two-story Georgian brick house and was the home of three generations of the Snowden family. The 260-acre (110 ha) parcel of land on which it stands was the nucleus of the Snowden family plantation. The family were slave holders and more than a hundred slaves were known to gather at Snowden Hall to listen to Bible readings on Sunday mornings.
The original Snowden Hall was constructed by Richard Snowden in the 18th century. The site is a portion of a 10,000-acre (4,000 ha) land grant from King Charles II. Sometime between 1812 and 1816 the Hall burned and was rebuilt as "Rose Cottage." Rose Cottage was subsequently raised to a full two stories in the 1850s. Former slave quarters and a large barn were on the east side of the property into the 1930s.
The property was purchased and renovated for government use in 1936, first as apartments and later as an office building. The low flanking wings were built at that time using bricks from the recently purchased pre-Civil War Duvall plantation house "Gladswood" on the southern section of the research center lands.
# Tritoma angulata

Tritoma angulata is a species of pleasing fungus beetle in the family Erotylidae. It is found in North America.
# List of closed railway stations in Greater Manchester
## Bolton

* Bolton Great Moor Street
* Chequerbent (1831 station)
* Chequerbent (1885 station)
* Chew Moor
* Darcy Lever
* Horwich
* Lostock Lane
* The Oaks
* Plodder Lane
* Rumworth and Daubhill

## Bury

* Ainsworth Road Halt
* Bradley Fold
* Brandlesholme Road Halt
* Bury Bolton Street (now preserved, as part of the East Lancashire Railway)
* Bury Knowsley Street
* Greenmount
* Holcombe Brook
* Knowles Level Crossing Halt
* Molyneux Brow
* Radcliffe Black Lane
* Radcliffe Bridge
* Ringley Road
* Sunny Wood Halt
* Tottington
* Withins Lane
* Woodhill Road Halt
* Woolfold

## Manchester

* Baguley
* Chorlton-cum-Hardy (converted to Metrolink)
* Clayton Bridge
* Dean Lane (converted to Metrolink)
* Didsbury
* Fallowfield
* High Street (Metrolink tram stop)
* Hyde Road
* Levenshulme South
* Longsight
* Manchester Central
* Manchester Liverpool Road
* Manchester Mayfield
* Manchester Oldham Road
* Miles Platting
* Mosley Street (Metrolink tram stop)
* Newton Heath
* Northenden
* Park
* Wilbraham Road
* Withington and West Didsbury
* Woodlands Road (Metrolink tram stop)

## Oldham

* Delph
* Derker (converted to Metrolink)
* Diggle
* Dobcross
* Failsworth (converted to Metrolink)
* Friezland
* Grasscroft
* Grotton and Springhead
* Hollinwood (converted to Metrolink)
* Lees
* Measurements
* Middleton Junction
* Moorgate
* Oldham Central
* Oldham Clegg Street
* Oldham Glodwick Road
* Oldham Mumps (converted to Metrolink)
* Oldham Mumps (LNWR)
* Oldham Werneth
* Royton
* Royton Junction
* Saddleworth
* Shaw and Crompton (converted to Metrolink)
* Uppermill

## Rochdale

* Broadfield
* Broadley
* Middleton
* Milnrow (converted to Metrolink)
* New Hey (converted to Metrolink as "Newhey")
* Shawclough and Healey
* Wardleworth

## Salford

* Agecroft Bridge
* Barton Moss
* Cadishead
* Cross Lane
* Dixon Fold
* Ellenbrook
* Irlams o' th' Height
* Little Hulton
* Manchester Exchange
* Monton Green
* Oldfield Road
* Ordsall Lane
* Pendlebury
* Pendleton
* Pendleton Bridge
* Seedley
* Walkden Low Level
* Weaste
* Worsley

## Stockport

* Cheadle (Cheshire Lines)
* Cheadle (LNWR)
* Cheadle Heath
* Hazel Grove (Midland)
* Heaton Mersey
* Heaton Norris
* Stockport Portwood
* Stockport Tiviot Dale
* High Lane
* Middlewood Higher

## Tameside

* Ashton Moss
* Ashton Oldham Road
* Ashton Park Parade
* Audenshaw (1st)
* Audenshaw (2nd)
* Droylsden
* Dukinfield & Ashton
* Dukinfield Central
* Godley East
* Hooley Hill
* Micklehurst
* Park Bridge
* Staley and Millbrook

## Trafford

* Altrincham (1st)
* Bowdon
* Broadheath
* Cornbrook (converted to Metrolink)
* Dunham (W&SR)
* Dunham Massey
* Partington
* West Timperley

## Wigan

* Astley
* Atherleigh
* Atherton Bag Lane
* Bickershaw and Abram
* Boar's Head
* Hindley Green
* Hindley South
* Howe Bridge
* Leigh
* Lower Ince
* Pennington
* Plank Lane
* Platt Bridge
* Tyldesley
* West Leigh
* West Leigh & Bedford
* Wigan Central
# Meregalli

Meregalli is an Italian surname. Notable people with the surname include:
* Guido Meregalli (1894–1959), Italian racing driver
* Luca Meregalli (born 1991), Italian footballer
# Unbreakable (horse)

Unbreakable (1935–1952) was an American-bred, British-trained Thoroughbred racehorse and sire. He was successful on the racecourse, but some way below the best of his generation. His best wins came in the Richmond Stakes at Goodwood as a two-year-old and in the Victoria Cup Handicap two years later. After his retirement from racing he became a highly successful breeding stallion: through his grandson Native Dancer he appears in the pedigrees of most modern Thoroughbreds.

## Background

Unbreakable was a black horse bred in the United States by his owner, Joseph E. Widener. He was sent to race in England, where he was trained by Cecil Boyd-Rochfort. The colt was sired by the British-bred stallion Sickle out of the French mare Blue Glass, making him a half-brother to the Belmont Stakes winner Hurryoff.

## Racing career

As a two-year-old, Unbreakable won three races including the Richmond Stakes at Goodwood in July. In the following year he competed at the highest level, finishing fifth to Pasch in the 2000 Guineas and eighth behind Bois Roussel in The Derby.

## Stud record

Unbreakable sired the Preakness Stakes winner Polynesian who in turn sired Native Dancer. One of the most highly rated American horses of the 20th century, Native Dancer was the grandsire of Mr. Prospector and the damsire of Northern Dancer. Unbreakable Died in 1952.

## Pedigree

Pedigree of Unbreakable, black stallion, 1935 :
| Sire Sickle brown 1924 | Phalaris br. 1913 | Polymelus b. 1902 | Cyllene |
| Sire Sickle brown 1924 | Phalaris br. 1913 | Polymelus b. 1902 | Maid Marian |
| Sire Sickle brown 1924 | Phalaris br. 1913 | Bromus b. 1905 | Sainfoin |
| Sire Sickle brown 1924 | Phalaris br. 1913 | Bromus b. 1905 | Cheery |
| Sire Sickle brown 1924 | Selene b. 1919 | Chaucer br. 1900 | St. Simon |
| Sire Sickle brown 1924 | Selene b. 1919 | Chaucer br. 1900 | Canterbury Pilgrim |
| Sire Sickle brown 1924 | Selene b. 1919 | Serenissima b. 1913 | Minoru |
| Sire Sickle brown 1924 | Selene b. 1919 | Serenissima b. 1913 | Gondolette |
| Dam Blue Glass brown 1917 | Prince Palatine b. 1908 | Persimmon b. 1893 | St. Simon |
| Dam Blue Glass brown 1917 | Prince Palatine b. 1908 | Persimmon b. 1893 | Perdita |
| Dam Blue Glass brown 1917 | Prince Palatine b. 1908 | Lady Lightfoot b. 1900 | Isinglass |
| Dam Blue Glass brown 1917 | Prince Palatine b. 1908 | Lady Lightfoot b. 1900 | Glare |
| Dam Blue Glass brown 1917 | Hour Glass blk. 1909 | Rock Sand br. 1900 | Sainfoin |
| Dam Blue Glass brown 1917 | Hour Glass blk. 1909 | Rock Sand br. 1900 | Roquebrune |
| Dam Blue Glass brown 1917 | Hour Glass blk. 1909 | Hautesse II br. 1891 | Archiduc |
| Dam Blue Glass brown 1917 | Hour Glass blk. 1909 | Hautesse II br. 1891 | Hauteur (Family 4-i) |
Unbreakable is inbred 4 × 4 to Sainfoin and St. Simon, meaning those stallions appear twice in the fourth generation of his pedigree.
# Transmission (Violent Delight album)

Transmission is the debut album by the English punk/metal band Violent Delight, it was released on 15 September 2003 and distributed by WEA records. The album fared poorly on the UK Albums Chart upon release reaching number 96, although it managed to reach number 12 on the UK Rock & Metal Albums Chart.

## Track listing

All tracks are written by Violent Delight

## Charts

Weekly charts
Chart (2003)
Peak position
UK Albums (OCC)
96
UK Rock & Metal Albums (OCC)
12 :
# WASP-26

WASP-26 is a yellow main sequence star in the constellation of Cetus.

## Star characteristics

WASP-26 is an old star close to leaving the main sequence and is part of a wide binary. The binary's projected separation is 3800 astronomical units, its companion star being a red dwarf with an effective temperature of 4600K and a visual magnitude of 13.6. WASP-26 produces a large amount of ultraviolet light due to frequent flares, with an average ultraviolet flux close to the F7 class main-sequence star WASP-1.

## Planetary system

The "Hot Jupiter" class planet WASP-26b was discovered around WASP-26 in 2010. The planet would have an equilibrium temperature of 1660±40 K, but measured temperatures are slightly higher at 1775K and no noticeable difference exists between the day-side and the night-side of the planet. A 2011 study using the Rossiter-McLaughlin effect failed to determine the inclination of the planetary orbit to the equatorial plane of the parent star due to high stellar noise, but an initial constraint of -34$^{+36}$ $_{−26}$° was published in 2012.
The WASP-26 planetary system :
| Companion (in order from star) | Mass | Semimajor axis (AU) | Orbital period (days) | Eccentricity | Inclination | Radius |
| b | 1.02±0.03 M$_J$ | 0.0400±0.0003 | 2.75660±0.00001 | 0 | 82.5±0.5° | 1.216±0.047 R$_J$ |