# Swimming at the 2022 European Aquatics Championships – Women's 4 × 100 metre medley relay

The Women's 4 × 100 metre medley relay competition of the 2022 European Aquatics Championships was held on 17 August 2022.

## Records

Prior to the competition, the existing European and championship records were as follows.
| | Team | Time | Location | Date |
| World record | United States | 3:50.40 | Gwangju | 28 July 2019 |
| European record | Russia | 3:53.38 | Budapest | 30 July 2017 |
| Championship record | Great Britain | 3:54.01 | Budapest | 23 May 2021 |

## Results
### Heats

The heats were started at 09:57.
| Rank | Heat | Lane | Nation | Swimmers | Time | Notes |
| 1 | 1 | 5 | Sweden | Hanna Rosvall (1:01.10) Sophie Hansson (1:07.11) Louise Hansson (56.97) Sarah Sjöström (54.01) | 3:59.19 | Q |
| 2 | 1 | 4 | Italy | Silvia Scalia (1:00.67) Lisa Angiolini (1:06.75) Elena Di Liddo (57.83) Chiara Tarantino (55.33) | 4:00.58 | Q |
| 3 | 2 | 6 | Netherlands | Kira Toussaint (1:00.73) Tes Schouten (1:07.21) Tessa Giele (59.06) Valerie van Roon (54.59) | 4:01.59 | Q |
| 4 | 2 | 4 | Great Britain | Medi Harris (1:00.68) Kara Hanlon (1:08.19) Holly Hibbott (1:00.80) Anna Hopkin (53.54) | 4:03.21 | Q |
| 5 | 1 | 2 | France | Emma Terebo (1:00.97) Adèle Blanchetière (1:09.66) Marie Wattel (59.33) Béryl Gastaldello (53.63) | 4:03.59 | Q |
| 6 | 2 | 3 | Poland | Laura Bernat (1:01.88) Dominika Sztandera (1:08.94) Julia Maik (59.13) Anna Dowgiert (54.91) | 4:04.86 | Q |
| 7 | 1 | 6 | Switzerland | Nina Kost (1:02.40) Lisa Mamié (1:08.40) Julia Ullmann (59.79) Maria Ugolkova (54.69) | 4:05.28 | Q |
| 8 | 2 | 7 | Germany | Johanna Roas (1:02.08) Bente Fischer (1:09.63) Angelina Köhler (58.23) Nele Schulze (55.47) | 4:05.41 | Q |
| 9 | 1 | 7 | Spain | Carmen Weiler (1:02.15) Jessica Vall (1:07.90) Carla Hurtado (1:01.06) Lidón Muñoz (54.67) | 4:05.78 | |
| 10 | 2 | 2 | Denmark | Karoline Sørensen (1:03.13) Thea Blomsterberg (1:07.98) Elisabeth Sabro Ebbesen (1:00.99) Julie Kepp Jensen (54.68) | 4:06.78 | |
| | 1 | 3 | Austria | | Did not start | Did not start |
| | 2 | 5 | Hungary | | Did not start | Did not start |

### Final

The final was held at 19:16.
| Rank | Lane | Nation | Swimmers | Time | Notes |
| | 4 | Sweden | Hanna Rosvall (1:00.66) Sophie Hansson (1:06.26) Louise Hansson (56.29) Sarah Sjöström (52.04) | 3:55.25 | |
| | 2 | France | Pauline Mahieu (1:00.17) Charlotte Bonnet (1:06.49) Marie Wattel (56.09) Béryl Gastaldello (53.61) | 3:56.36 | NR |
| | 3 | Netherlands | Kira Toussaint (1:00.29) Tes Schouten (1:06.75) Maaike de Waard (57.74) Marrit Steenbergen (52.23) | 3:57.01 | NR |
| 4 | 5 | Italy | Margherita Panziera (59.78) Benedetta Pilato (1:05.65) Ilaria Bianchi (58.37) Silvia Di Pietro (53.43) | 3:57.23 | |
| 5 | 6 | Great Britain | Medi Harris (1:00.09) Kara Hanlon (1:07.49) Keanna MacInnes (58.62) Freya Anderson (53.85) | 4:00.05 | |
| 6 | 7 | Poland | Paulina Peda (1:01.09) Dominika Sztandera (1:08.47) Julia Maik (58.73) Aleksandra Polańska (54.24) | 4:02.53 | NR |
| 7 | 1 | Switzerland | Nina Kost (1:02.53) Lisa Mamié (1:07.05) Julia Ullmann (59.69) Maria Ugolkova (54.67) | 4:03.94 | |
| 8 | 8 | Germany | Johanna Roas (1:02.11) Bente Fischer (1:09.59) Angelina Köhler (58.61 ) Nele Schulze (55.29) | 4:05.60 | |