OpenLLM-France/wikimedia huggingface dataset:
# KDM2B

The human KDM2B gene encodes the protein lysine (K)-specific demethylase 2B.

## Tissue and subcellular distribution

KDM2B is broadly and highly expressed in embryonic tissues (especially in the developing central nervous system of vertebrates). Expression of KDM2B is also retained in most organs in adults. The protein is present in the nucleoplasm and is enriched in the nucleolus where it binds the transcribed region of ribosomal RNA to represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation.

## Structure

KDM2B protein has several domains including a JmjC domain that has a histone demethylase activity demethylating trimethylated Lys-4 and dimethylated Lys-36 of histone H3. KDM2B specifically recognizes and bind non-methylated DNA in CpG islands through its ZF-CxxC DNA binding domain. KDM2B consequently recruits the non-canonical polycomb repressive complex 1.1 (ncPRC1) to unmethylated CpG islands via a direct interaction with BCOR and PCGF1 leading to the mono-ubiquitylation of histone H2A on K119 and gene repression.

## Function

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
As part of the ncPRC1.1 complex, KDM2B was found to be rapidly and transiently recruited to sites of DNA damage in a PARP1- and TIMELESS-dependent manner to promote mono-ubiquitylation of histone H2A on K119 with concomitant local decrease of H2A levels and an increase of H2A.Z. These events promote transcriptional repression at DNA lesions, double strand break signaling, and homologous recombination repair. The activity of the ncPRC1.1 complex at DNA lesions was necessary for the proper recruitment of the two canonical PRC1 complexes (cPRC1.2 and cPRC1.4), defined by their PCGF subunits, MEL18 and BMI1 respectively. Therefore, recruitment of the ncPRC1.1 complex represents an early and critical regulatory step in homologous recombination repair.

## Clinical significance

Loss of KDM2B leads to severe developmental defects (growth defects in the brain, including failure of neural tube closure and craniofacial malformations, hematopoietic development) leading to embryonic lethality
# Duarte Gomes

Duarte Nuno Pereira Gomes (born 16 January 1973) is a Portuguese retired football referee and media personality.
He started his career as a referee in 1991 at the district levels, ascending gradually to the first national category in 1997. He became an international referee in 2002. Besides domestic competitions, he also officiated at UEFA and FIFA matches.
He retired in 2016 and dedicated to media interests. Currently he participates in the football programme O Dia Seguinte at SIC Notícias, where he comments about controversial refereeing decisions. He previously authored the programme Ó Sr. Árbitro, also at SIC Notícias, which shed a light on refereeing in district football competitions He is also the author of the book and website Kickoff, launched in August 2017, which aims to explain the game rules and the role of the referees to the general public.
# Erwin Sellering

Erwin Sellering (born 18 October 1949) is a German politician. He served as the 4th Minister President of Mecklenburg-Vorpommern from 2008 to 2017.

## Early life and career

Sellering studied law and has lived in Mecklenburg-Vorpommern since 1994, where he worked at the courts of Schwerin and Greifswald.

## Political career

Being a member of the Social Democratic Party of Germany, he has held various positions in the government of Mecklenburg-Vorpommern since 1998 - first as a state secretary, later as Minister for Justice, and since 2006 as Minister for Social Affairs. In 2007, he became chairman of Mecklenburg-Vorpommern's Social Democratic Party. In 2008, he succeeded Harald Ringstorff as Mecklenburg-Vorpommern's prime minister. He is also a member of the German-Russian Friendship Group set up by the German Bundesrat and the Russian Federation Council.
In the 2016 state elections, Sellering and his SPD garnered a better-than-forecast 30.6 percent. He had campaigned on local issues, urging voters to focus on jobs creation in the wind turbine sector, decentralized integration of refugees and pension parity with Germany's western regions.
Between October 2016 and May 2017, Sellering chaired the Conference of Ministers-President. He was a SPD delegate to the Federal Convention for the purpose of electing the President of Germany in 2017.
On 30 May 2017 Sellering announced his resignation from all official political positions after he had been diagnosed with lymph cancer that needed immediate treatment. He proposed as his replacement Manuela Schwesig.

## Political positions

Sellering is known for taking a hard line against neo-Nazis and for supporting families.

## Life after politics

From 2021 to 2022, Selling served as chairman of the Stiftung Klima- und Umweltschutz MV (Climate and Environment Protection Foundation), an entity set up by the government of Mecklenburg-Vorpommern in January 2021 and endowed with 20 million euros from Nord Stream 2 AG, a Switzerland-based company owned by Gazprom.

## Other activities

* Festspiele Mecklenburg-Vorpommern, Patron
* Deutsches Museum, Member of the Board of Trustees
* KfW, Member of the Board of Supervisory Directors (2013-2015)

## Personal life

Sellering is married, has two children and currently resides in Greifswald.
# Caelostomus rectangulus

Caelostomus rectangulus is a species in the ground beetle family Carabidae. It is found in Southeast Asia.
This species was described by Maximilien Chaudoir in 1873.
# Pyroxmangite

Pyroxmangite has the general chemical formula of MnSiO$_3$. It is the high-pressure, low-temperature dimorph of rhodonite.
It was first described in 1913 and named for the mineral group, pyroxenes, and is known as the manganese member. It forms a series with pyroxferroite.
Pyroxmangite occurs in metamorphosed ore deposits rich in manganese. Associated minerals include spessartine, tephroite, alleghanyite, hausmannite, pyrophanite, alabandite, rhodonite and rhodochrosite.
# Rigney, Doubs

Rigney (French pronunciation:) is a commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France. Its hamlet La Roche-sur-l'Ognon is also the most likely place of origin of the first ducal family of the Duchy of Athens, the de la Roche family.
# Lulu Town

Lulu Town, also known as Lulu Ville, is a now uninhabited, former settlement on Navassa Island, claimed by both the United States and neighbouring Haiti, in the Windward Passage.

## Overview

Navassa Island was claimed for the United States on September 19, 1857, by Peter Duncan, an American sea captain, under the Guano Islands Act of August 18, 1856. The modest settlement was created to house both mine workers and supervisors whose goal was the rich deposits of guano found on Navassa. This resource, gathered mainly from the interior of the island, was stored in Lulu Town for later shipment to the United States.
Mining operations on Navassa Island were halted and the island evacuated in 1899 during the Spanish–American War. In 1901 the Navassa Phosphate Co. filed for bankruptcy and abandoned Lulu Town and rest of the island.
The town lies on Lulu Bay. Its ruggedness prevents boats from landing; such small boats as regularly ply the area are mainly fishing boats from nearby Haiti.
# QF

QF may stand for:

## Businesses and organisations

* Qantas, an Australian airline (IATA:QF)
* Qatar Foundation, a non-profit
* Quiverfull, a Christian movement

## Military

* Quds Force, an Iranian expeditionary unit
* Quick-firing gun, an artillery piece
* A gun breech that uses metallic cartridges; see British ordnance terms#QF
* Q-Fire, a decoy fire site used in World War II

## Other uses

* Quality factor, in physics and engineering, a measure of the "quality" of a resonant system
# Mira Gonzalez

Mira Gonzalez (born May 28, 1992) is an American poet. Her first collection, i will never be beautiful enough to make us beautiful together, was published by Spencer Madsen of Sorry House press on January 31, 2013. According to Liza Darwin in Nylon magazine, Gonzalez is part of a "whole new crop of cool girl poets" whose work is "clever, totally unfiltered, and peppered with twisted insight and refreshing humor." She has been published in magazines including Vice, Hobart, and Muumuu House. In 2015, Gonzalez and Tao Lin released Selected Tweets, a collaborative double-book featuring selections from three of her Twitter accounts, as well as visual art and "extras". In 2015, the singer Lily Allen posted an image of her hand above Gonzalez's i will not be beautiful enough... book of poems, which led to speculation that the singer's marriage was on shaky ground. Gonzalez has described her writing process as follows:
   I will spend hours on one sentence sometimes, and if I feel that sentence isn’t expressing exactly what I want it to express, I will delete the sentence entirely. I think it takes a lot of precision and tedious work.
She is from Los Angeles, California.

## Awards

Dazed & Confused magazine chose i will never be beautiful enough to make us beautiful together as its poetry book of the week, comparing Gonzalez to Tao Lin as a writer with a prolific and intense social media presence. In 2014 the collection was a finalist for The Believer magazine's Poetry Award. Flavorwire, an online culture magazine, named Gonzalez one of "23 People Who Will Make You Care About Poetry in 2013".

## Reviews

A review in Rumpus magazine described i will never be beautiful enough to make us beautiful together as about "disconnected sex, anxiety, loneliness, drugs, and depression" but with "cool, effervescent, and clear" observations. In one poem, according to reviewer Emily Bludworth de Barrios, Gonzalez repeats a sequence of words for emphasis, a technique sometimes called anaphora, to emphasize emotion. A review described her writing as having "brutal honesty and minimalist vocabulary and diction." A review in Economy magazine described her poems as having a "studied laboriousness" which was "weirdly compelling." Filmmaker and screenwriter Lena Dunham wrote in The Guardian that the book was one of her favorites for 2014, and that it brings "experimental poetry into the internet age with dark, distinctly female riffs on ambition, depression and love." Reviewer Emma-Lee Moss in The Guardian wrote that Gonzalez's persona is "radical in its contradictions – her voice is both punk and disinterested, both promiscuous and not particularly sexual." The New Inquiry called Gonzalez's poetry "a paragon of flat writing and ambivalence toward emotion" that "conjures an affectively messy universe."

## Personal life

Gonzalez is the daughter of visual artist Lora Norton and the stepdaughter of Black Flag bassist Chuck Dukowski. Her mother, stepfather and brother Milo are members of the Chuck Dukowski Sextet.
# Duff-Gordon baronets

The Duff (later Duff-Gordon) baronetcy, of Halkin in the County of Aberdeen, is a title in the Baronetage of the United Kingdom. It was created on 12 November 1813 for James Duff, British Consul in Cádiz, with remainder to his nephew, William Gordon.
Duff died unmarried in 1815 and was succeeded according to the special remainder by his nephew, the 2nd Baronet, who assumed the additional surname of Duff on succeeding to the title. He was the second son of Lord Rockville, fourth son of the 2nd Earl of Aberdeen. Duff-Gordon sat as Member of Parliament for Worcester.
Lucy, Lady Duff-Gordon, wife of the fifth Baronet, was a leading fashion designer; and, together with her sister Elinor Glyn, was one of the original 'It' girls.

## Duff (later Duff-Gordon) baronets, of Halkin (1813)

* Sir James Duff, 1st Baronet (1734–1815)
* Sir William Duff-Gordon, 2nd Baronet (1772–1823)
* Sir Alexander Cornewall Duff-Gordon, 3rd Baronet (1811–1872)
* Sir Maurice Duff-Gordon, 4th Baronet (1849–1896)
* Sir Cosmo Edmund Duff-Gordon, 5th Baronet (1862–1931)
* Sir Henry William Duff-Gordon, 6th Baronet (1866–1953)
* Sir Douglas Frederick Duff-Gordon, 7th Baronet (1892–1964)
* Sir Andrew Cosmo Lewis Duff-Gordon, 8th Baronet (1933–2023)
* Sir Cosmo Henry Villiers Duff-Gordon, 9th Baronet (born 1968). His son Jack Charles Villiers Duff-Gordon, born 2006, is his heir.
# List of drugs used to treat schistosomiasis

A schistosomicide is a drug used to combat schistosomiasis.

## List

Examples listed in MeSH include:
* amoscanate
* arteether
* artemether
* chloroxylenol
* hycanthone
* lucanthone
* metrifonate
* niridazole
* oltipraz
* oxamniquine
* praziquantel
* stibophen
# Kit Clayton

Joshua Kit Clayton, better known by his stage name Kit Clayton, is a San Francisco-based electronic and digital musician and computer programmer. He is a developer at San Francisco software company Cycling '74, helping create the Max/MSP MIDI/audio programming environment. He is also a significant contributor to Jitter, the multi-dimensional data set processing and visualizing architecture for audio, video, and 3D graphics (part of the Max multimedia package). Clayton uses Max, MSP, and Jitter extensively in his own abstract musical compositions, which have been described as including aspects of ambient computer music and glitch.
In 2000 Clayton founded and operated his own label, Orthlorng Musork. Musork released seminal works by AGF, Akira Rabelais, Alejandra and Aeron, Kevin Blechdom, Blevin Blectum, Blectum from Blechdom, Eight Frozen Modules, Gold Chains, Secret Mommy, Stephan Mathieu, Sutekh, Timeblind, and others, until closing in 2004. Musork announced its final release and the closing of label operations with the following statement:
"Why do we stop? The simple and honest truth is that we want to devote our time to other creative things. We still love music and we will still be active and supportive of the scene. We aren't in financial ruin, we don't think p2p networks have destroyed the music industry, we don't only want to listen to country western, we just want to take on other projects with as much love and intensity as we did this one."
He continues to compose, perform and develop Max/MSP, and Jitter.
Clayton graduated from Wesleyan University, where he studied electronic music and computer science.
# Masonic Temple (Lewistown, Montana)

The Masonic Temple in Lewistown, Montana, also known as the Lewistown Lodge No. 37 A.F. & A.M., is a building from 1908. It was listed on the National Register of Historic Places in 1979.
It is a standalone three-story building, with basement, at the corner of Fourth Avenue North and West Broadway Street in Lewistown. Up to the ceremonial placement of the building's cornerstone on August 20, 1908, almost all of the stonecutters, masons, and others involved with its construction had come from the nation of Croatia, including Peter Tuss, the stonemason who was the contractor for the building's construction.
# Iontocaine

Iontocaine was an anesthetic medication, marketed under the two brand names Numby and Phoresor PM900 by IOMED inc. It is a local anesthetic with vasoconstrictor, administered via iontophoresis through the skin. It can numb up to 10 mm of skin in as little as 10 minutes. It is a 2% lidocaine, 0.01 mg/ml epinephrine solution. It was manufactured by IOMED, Inc.
Iontocaine was approved by the United States Food and Drug Administration on 21 December 1995. It was discontinued by the manufacturer in 2005.
# Charles Gordon (parliamentary official)

Sir Charles Addison Somerville Snowden Gordon, KCB (25 July 1918 – 1 March 2009) was an English parliamentary clerk.

## Early life, education and war service

Born on 25 July 1918, Gordon was the son of Charles Gordon Snowden Gordon, a barrister from Liverpool. After attending Winchester College, he went up to Balliol College, Oxford, as a Domus scholar in 1936. He graduated in 1939 with a second-class honours degree in modern history. He then spent the Second World War with the Fleet Air Arm, before joining the House of Commons Department as an Assistant Clerk in 1946. According to The Independent, "His analytical skills and his articulacy ... made him a 'natural' Clerk and he became a first-class proceduralist".

## Career and later life

In 1947, he was promoted to Senior Clerk, and in 1962 became Fourth Clerk at the Table. The following year, he was appointed head of the Overseas Office (serving until 1969) and advised new Commonwealth parliaments on procedure. Promotion followed in 1967, when he became Principal Clerk of the Table Office, in 1974 on appointment as Second Clerk Assistant, and then two years later when he became Clerk Assistant. He had to advise on bills establishing the assemblies of Scotland and Wales, debates over which went on late into the night for consecutive days. In 1979, he was appointed Clerk to the House of Commons; during his tenure, which lasted until 1983, he authored the 20th version of Erskine May.
Gordon was appointed a Companion of the Order of the Bath in the 1970 Birthday Honours, and in the 1981 Birthday Honours was promoted to Knight Commander. His wife, Janet Beattie, died in 1995, and his last years were spent with his partner, Pamela Fernant. He died on 1 March 2009, leaving a son; his daughter predeceased him.
# Lindsey Chapman

Lindsey Katherine Chapman (born 1984 or 1985) is an English television and radio presenter.

## Career

Chapman, the daughter of a teacher and a rural developer, was educated at Lockington primary school and Beverley High School before studying Drama and Theatre Arts at the University of Birmingham and later trained at Birmingham School of Acting. Growing up, she was a member of the Girl Guides.
In August 2015 Chapman hosted Big Blue UK, a series on UK marine wildlife, alongside Hugh Fearnley-Whittingstall for BBC One.
In January 2016, she co-hosted BBC Two's Winterwatch Unsprung with Chris Packham. She continued this role with Springwatch Unsprung in June 2016 and 2017 and in an online version of Winterwatch Unsprung in January 2017. Chapman has also presented Songs of Praise for the BBC and appeared on their wildlife-themed panel show Curious Creatures.
Since 2018 Chapman has presented series of Channel 5's Springtime on the Farm, Animals After Dark and Wild Animal Rescue.
On radio, Chapman has presented episodes of BBC Radio 4's Tweet of the Day and Tweet of the Week, Pick of the Week, Costing the Earth, Living World, Opening Night and In Pursuit of Beauty. She also presented the Contains Strong Language poetry special alongside Jeremy Irons and Julie Hesmondhalgh, part of the station's Hull UK City of Culture 2017 programming. Chapman has also hosted online arts coverage for the corporation for events such as the Edinburgh Festival Fringe, Shakespeare Lives, Opera Passion Day and Get Creative.
Chapman has worked as a travel reporter for BBC Radio 5 Live. In 2019, she commentated on international netball for the station and has previously presented coverage of matches for Sky Sports.
Chapman has been a patron of the Wild Watch programme in Nidderdale area of outstanding natural beauty, the Yorkshire Dales Millennium Trust, the City of Trees programme in Greater Manchester and the Wild Otter Trust. She has also presented at the Greater Manchester Green Summit and the Manchester Climate Change Conference. Chapman was also a torchbearer in the London 2012 Olympic Torch procession and in same year was part of BBC Radio 5 Live Guinness World Record attempt for the ‘most players in a continuous 5 a side exhibition match’ for BBC Children in Need.
# QFAB Bioinformatics

QFAB Bioinformatics is a Queensland-based organisation concerned with the provision of resources in bioinformatics, biostatistics and specialised computing platforms. QFAB operates Australia-wide and is a key contributor to the EMBL Australia Bioinformatics Resource.

## History

QFAB was established in 2007, with funding from the Queensland Government's National and International Research Alliances Program, as a joint venture between The University of Queensland, Queensland University of Technology, Griffith University, CSIRO’s Australian eHealth Research Centre and the Queensland Government’s Department of Agriculture, Fisheries and Forestry.
Mark Ragan from the Institute of Molecular Bioscience (IMB) and Anthony Maeder from the Australian eHealth Research Centre led QFAB's establishment and appointed Jeremy Barker as CEO (2007–2014) to address three critical issues then facing bioinformatics in Queensland:
* integrated data and high-performance computing in a secure environment
* affordable network bandwidth
* access to expert personnel
In 2015, Dominique Gorse became CEO of QFAB and led the strategic alliance with QCIF, the Queensland Cyber Infrastructure Foundation; the two organisations merged in April 2016. QCIF operates significant high-performance computing, cloud computing and data storage resources, is part of the national eResearch infrastructure.

## Queensland Cyber Infrastructure Foundation

QFAB Bioinformatics is a unit of the Queensland Cyber Infrastructure Foundation (QCIF), a not-for-profit member-based organisation.

### Members

* Central Queensland University
* Griffith University
* James Cook University
* Queensland University of Technology
* The University of Queensland
* University of Southern Queensland

### Affiliate member

* University of the Sunshine Coast

## Galaxy Australia

QFAB and QCIF, together with the University of Melbourne's Melbourne Bioinformatics, and the University of Queensland's Research Computing Centre jointly built and operate Galaxy Australia, which is a major feature of the Genomics Virtual Laboratory, based on the Galaxy (computational biology) scientific workflow system.
# KOMC

KOMC may refer to:
* KOMC-FM, a radio station (100.1 FM) licensed to serve Kimberling City, Missouri
* KCAX, a radio station (1220 AM) licensed to serve Branson, Missouri, United States, which held the call sign KOMC from 1986 to 2016
# Dupps

The Dupps were a professional wrestling tag team in southern independents and ECW during the late 1990s composed of four wrestlers and one valet. Each of their names is a play on different phrases: "Bowed up", "Jacked up", "Pucked up", "Stand up", and "Fluffed up". They feuded with Danny Doring and Roadkill over who should have a shot at the ECW World Tag Team Championship. The rivalry culminated when The Dupps signed a World Wrestling Federation developmental deal, resulting in a loser leaves town match on the February 25, 2000 episode of ECW on TNN, that the Dupps lost.
After a long stint in the WWF/E developmental system and primarily wrestling infrequently on WWF Jakked, both Dupps were eventually let go in 2001. During their time in the WWF they feuded with the Mean Street Posse.
During the early days of NWA Total Nonstop Action, the team consisted of Bo Dupp and Stan Dupp, and managed by Fluff Dupp. Bo, Stan and Fluff were stereotypical southerners, frequently chewing tobacco and teasing an incestuous relationship. The Dupps became the first Champions of the "Dupp Cup" but lost it to the "Hardcore Midget" Teo.
Stan Dupp went on to use a similar gimmick in World Wrestling Entertainment as "Trevor Murdoch", before being released in July 2008. He returned to TNA in 2009 under the same gimmick as well, though with the name "Jethro Holliday" this time.

## Championships and accomplishments

* Carolina Wrestling Federation
** CWF Mid-Atlantic Tag Team Championship (1 time)
* Memphis Championship Wrestling
** MCW Southern Tag Team Championship (2 times) - Bo and Jack
* NWA Total Nonstop Action
** Dupp Cup
* OMEGA
* OMEGA Tag Team Championship (1 time)
* Southern Championship Wrestling
** SCW Tag Team Championship (1 time)