# List of Ultratop 50 number-one singles of 2016

These hits topped the Ultratop 50 in 2016.
Flanders :
| Issue date | Song | Artist |
| 2 January | "Hello" | Adele |
| 9 January | "Hello" | Adele |
| 16 January | "Hello" | Adele |
| 23 January | "Fortune Cookie" | Emma Bale featuring Milow |
| 30 January | "7 Years" | Lukas Graham |
| 6 February | "7 Years" | Lukas Graham |
| 13 February | "7 Years" | Lukas Graham |
| 20 February | "7 Years" | Lukas Graham |
| 27 February | "7 Years" | Lukas Graham |
| 5 March | "7 Years" | Lukas Graham |
| 12 March | "7 Years" | Lukas Graham |
| 19 March | "Be the One" | Dua Lipa |
| 26 March | "7 Years" | Lukas Graham |
| 2 April | "7 Years" | Lukas Graham |
| 9 April | "7 Years" | Lukas Graham |
| 16 April | "I Took a Pill in Ibiza" | Mike Posner |
| 23 April | "I Took a Pill in Ibiza" | Mike Posner |
| 30 April | "I Took a Pill in Ibiza" | Mike Posner |
| 7 May | "One Dance" | Drake featuring Wizkid and Kyla |
| 14 May | "One Dance" | Drake featuring Wizkid and Kyla |
| 21 May | "One Dance" | Drake featuring Wizkid and Kyla |
| 28 May | "Can't Stop the Feeling!" | Justin Timberlake |
| 4 June | "Can't Stop the Feeling!" | Justin Timberlake |
| 11 June | "Can't Stop the Feeling!" | Justin Timberlake |
| 18 June | "Can't Stop the Feeling!" | Justin Timberlake |
| 25 June | "Can't Stop the Feeling!" | Justin Timberlake |
| 2 July | "Can't Stop the Feeling!" | Justin Timberlake |
| 9 July | "Can't Stop the Feeling!" | Justin Timberlake |
| 16 July | "Can't Stop the Feeling!" | Justin Timberlake |
| 23 July | "Can't Stop the Feeling!" | Justin Timberlake |
| 30 July | "Can't Stop the Feeling!" | Justin Timberlake |
| 6 August | "Can't Stop the Feeling!" | Justin Timberlake |
| 13 August | "Beautiful Life" | Lost Frequencies featuring Sandro Cavazza |
| 20 August | "Can't Stop the Feeling!" | Justin Timberlake |
| 27 August | "Can't Stop the Feeling!" | Justin Timberlake |
| 3 September | "Sofia" | Álvaro Soler |
| 10 September | "Can't Stop the Feeling!" | Justin Timberlake |
| 17 September | "Closer" | The Chainsmokers featuring Halsey |
| 24 September | "Closer" | The Chainsmokers featuring Halsey |
| 1 October | "Closer" | The Chainsmokers featuring Halsey |
| 8 October | "Closer" | The Chainsmokers featuring Halsey |
| 15 October | "Closer" | The Chainsmokers featuring Halsey |
| 22 October | "Closer" | The Chainsmokers featuring Halsey |
| 29 October | "Human" | Rag'n'Bone Man |
| 5 November | "Human" | Rag'n'Bone Man |
| 12 November | "Human" | Rag'n'Bone Man |
| 19 November | "What Is Love 2016" | Lost Frequencies |
| 26 November | "What Is Love 2016" | Lost Frequencies |
| 3 December | "Human" | Rag'n'Bone Man |
| 10 December | "What Is Love 2016" | Lost Frequencies |
| 17 December | "Human" | Rag'n'Bone Man |
| 24 December | "Hey Baby" | Dimitri Vegas & Like Mike vs. Diplo featuring Deb's Daughter |
| 31 December | "Human" | Rag'n'Bone Man |
| Position | Artist | Weeks #1 |
| 1 | Justin Timberlake | 14 |
| 2 | Lukas Graham | 11 |
| 3 | The Chainsmokers | 6 |
| 3 | Halsey | 6 |
| 3 | Rag'n'Bone Man | 6 |
| 4 | Lost Frequencies | 4 |
| 5 | Adele | 3 |
| 5 | Drake | 3 |
| 5 | Wizkid (as featuring) | 3 |
| 5 | Kyla (as featuring) | 3 |
| 5 | Mike Posner | 3 |
| 6 | Dua Lipa | 1 |
| 6 | Emma Bale | 1 |
| 6 | Milow | 1 |
| 6 | Sandro Cavazza (as featuring) | 1 |
| 6 | Álvaro Soler | 1 |
| 6 | Dimitri Vegas & Like Mike | 1 |
| 6 | Diplo | 1 |
| 6 | Deb's Daughter | 1 |
Wallonia :
| Issue date | Song | Artist |
| 2 January | "Hello" | Adele |
| 9 January | "Hello" | Adele |
| 16 January | "Hello" | Adele |
| 23 January | "Hello" | Adele |
| 30 January | "Hello" | Adele |
| 6 February | "Hello" | Adele |
| 13 February | "Hello" | Adele |
| 20 February | "Hello" | Adele |
| 27 February | "Hello" | Adele |
| 5 March | "Work" | Rihanna featuring Drake |
| 12 March | "Hundred Miles" | Yall featuring Gabriela Richardson |
| 19 March | "Hundred Miles" | Yall featuring Gabriela Richardson |
| 26 March | "Hundred Miles" | Yall featuring Gabriela Richardson |
| 2 April | "Faded" | Alan Walker |
| 9 April | "Faded" | Alan Walker |
| 16 April | "Faded" | Alan Walker |
| 23 April | "Faded" | Alan Walker |
| 30 April | "I Took a Pill in Ibiza" | Mike Posner |
| 7 May | "I Took a Pill in Ibiza" | Mike Posner |
| 14 May | "Cheap Thrills" | Sia featuring Sean Paul |
| 21 May | "I Took a Pill in Ibiza" | Mike Posner |
| 28 May | "I Took a Pill in Ibiza" | Mike Posner |
| 4 June | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 11 June | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 18 June | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 25 June | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 2 July | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 9 July | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 16 July | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 23 July | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 30 July | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 6 August | "Can't Stop the Feeling!" | Justin Timberlake |
| 13 August | "Can't Stop the Feeling!" | Justin Timberlake |
| 20 August | "Can't Stop the Feeling!" | Justin Timberlake |
| 27 August | "Can't Stop the Feeling!" | Justin Timberlake |
| 3 September | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 10 September | "This Girl" | Kungs vs. Cookin' on 3 Burners |
| 17 September | "Beautiful Life" | Lost Frequencies featuring Sandro Cavazza |
| 24 September | "Beautiful Life" | Lost Frequencies featuring Sandro Cavazza |
| 1 October | "Cold Water" | Major Lazer featuring Justin Bieber and MØ |
| 8 October | "Beautiful Life" | Lost Frequencies featuring Sandro Cavazza |
| 15 October | "Aloha" | Møme featuring Merryn Jeann |
| 22 October | "Lost on You" | LP |
| 29 October | "Lost on You" | LP |
| 5 November | "Lost on You" | LP |
| 12 November | "The Greatest" | Sia featuring Kendrick Lamar |
| 19 November | "The Greatest" | Sia featuring Kendrick Lamar |
| 26 November | "Human" | Rag'n'Bone Man |
| 3 December | "Starboy" | The Weeknd featuring Daft Punk |
| 10 December | "Starboy" | The Weeknd featuring Daft Punk |
| 17 December | "Lost on You" | LP |
| 24 December | "Starboy" | The Weeknd featuring Daft Punk |
| 31 December | "Human" | Rag'n'Bone Man |
| Position | Artist | Weeks #1 |
| 1 | Kungs | 11 |
| 1 | Cookin' on 3 Burners | 11 |
| 2 | Adele | 9 |
| 3 | Alan Walker | 4 |
| 3 | Mike Posner | 4 |
| 3 | Justin Timberlake | 4 |
| 3 | LP | 4 |
| 4 | Yall | 3 |
| 4 | Gabriela Richardson (as featuring) | 3 |
| 4 | Lost Frequencies | 3 |
| 4 | Sandro Cavazza (as featuring) | 3 |
| 4 | Sia | 3 |
| 4 | The Weeknd | 3 |
| 4 | Daft Punk (as featuring) | 3 |
| 5 | Kendrick Lamar | 2 |
| 5 | Rag'n'Bone Man | 2 |
| 6 | Rihanna | 1 |
| 6 | Drake (as featuring) | 1 |
| 6 | Sean Paul (as featuring) | 1 |
| 6 | Major Lazer | 1 |
| 6 | Justin Bieber as featuring) | 1 |
| 6 | MØ (as featuring) | 1 |
| 6 | Møme | 1 |
| 6 | Merryn Jeann | 1 |