OpenLLM-France/wikimedia huggingface dataset:
# Mitochondrial processing peptidase

Mitochondrial processing peptidase is an enzyme complex found in mitochondria which cleaves signal sequences from mitochondrial proteins. In humans this complex is composed of two subunits encoded by the genes PMPCA, and PMPCB. The enzyme is also known as (EC 3.4.24.64, processing enhancing peptidase (for one of two subunits), mitochondrial protein precursor-processing proteinase, matrix peptidase, matrix processing peptidase, matrix processing proteinase, or MPP). This enzyme catalyses the following chemical reaction
    Release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2
This enzyme is present the mitochondrial matrix of fungi and mammals.

## Function

Mitochondria import the majority of their proteins from the cell cytosol. In order to achieve this, many mitochondrial proteins encode a short targeting signal which directs them to the mitochondrion and through its preprotein translocase machinery. Mitochondrial proteins which reach the innermost mitochondrial compartment, the Mitochondrial matrix, often undergo proteolytic cleavage of the targeting signal, performed by the Mitochondrial Processing Peptidase (MPP), this is often necessary for the maturation of the preprotein to its functional form or to reveal additional targeting sequences.
In most eukaryotes, the MPP consists of two subunits, an α and β subunit which bind together to form a heterodimeric complex. In humans these are the genes PMPCA and PMPCB. The subunits of the MPP are highly conserved, and have shown to be interoperable between species, homologues to MPPs are also found in eukaryotes whose mitochondria have evolved into divergent organelles, though in the case of Trichomonas the processing peptidase complex appears to be made of two β subunits.

## Structure and Mechanism

The X-ray structures of yeast MPP, and a cleavage-deficient MPP with substrate bound, are available. The sequence around the scissile bond binds as a beta strand in such a way that the scissile bond aligns with the zinc binding site to allow nucleophilic attack by a zinc—coordinated water molecule on the carbonyl carbon of the residue before the scissile bond (last residue of the signal peptide).

## Evolution

The origins of the mitochondrial processing peptidases are thought to be prokaryotic in origin, possibly originating in the endosymbiont which developed into the mitochondrion, this hypothesis has been supported by the discovery of a bacterial signal peptidase in Rickettsia, an organism thought to be a closely related to the mitochondrial progenitor. Experimentally this peptidase was shown to cleave signal sequences from mitochondrial proteins.
# Frischmann

Frischmann is a surname of German origin, being a variant of the surnames Frisch and Frischman. Notable people with the surname include:
* David Frischmann (1859-1922), Hebrew and Yiddish modernist writer, poet, and translator
* Jörg Frischmann (born 1963), German Paralympic athlete
* Justine Frischmann (born 1969), English artist and retired musician
* Wilem Frischmann (born 1931), British engineer
# Parish Pastoral Council for Responsible Voting

The Parish Pastoral Council for Responsible Voting (PPCRV) is a non-partisan, non-sectarian non-profit organization affiliated with the Catholic Church in the Philippines that works to ensure free, fair and fraud-free elections in the Philippines. The organization has been the "citizens' arm" of the Commission of Elections since 2010. PPCRV conducts the Unofficial Parallel Count of returns after the election.
PPCRV's activity includes advocating for electoral reforms, conducting parallel manual auditing in automated elections, coordinating parishes to conduct poll-watching, providing legal assistance related to elections, reporting of electoral violations, providing voters' assistance services, and voters' education.

## History

The Second Plenary Council of the Philippines, held in February 1991, called for reforms in the conduct of elections in the Philippines. In May 1991, Cardinal Jaime Sin, Archbishop of Manila, Commission on Elections (Philippines) Commissioner Haydee Yorac, then-Laity President Henrietta T. de Villa, Gabriel Reyes, Bayani Valenzuela, and thirty parish lay leaders conceived of the idea of the PPCRV in Mandaluyong. In October 1991, the PPCRV was launched at St. Paul University, Quezon City, with around one thousand laypeople from the parishes of the Archdiocese of Manila. The next month, with the support of the Catholic Bishops' Conference of the Philippines, the PPCRV expanded its operations nationwide.
PPCRV's poll-watching activities began with the 1992 presidential elections. Then, 346,688 PPCRV volunteers participated in poll-watching, voters’ assistance, assisting the Board of Election Inspectors, protecting election returns, monitoring electoral exercise, and watching the canvassing of votes.

## Relation with COMELEC

In April 2013, PPCRV was accused by the Archbishop of Lipa Ramon Arguelles of being a COMELEC lapdog since the conduct of the 2010 general elections, an allegation that the chairperson of PPCRV, Henrietta T. de Villa, disputes. The organization has been a "citizens arm" of the Commission of Elections since 2010.
In 2010, it had objected to the National Movement for Free Elections' (NAMFREL) application as a citizen's arm of COMELEC, stating that a dual system would interfere with election watch. NAMFREL had never objected to PPCRV's applications as a citizen arm in previous elections. The feud seems to be over as both parties were accredited by COMELEC for the 2013 midterm elections and agreed on their respective functions.
# Hunts Corners

Hunts Corners, Hunt's Corner, Hunt Corner, or, variation, may refer to:
* Hunts Corners, Ohio, USA; an unincorporated community in Lyme Township, Huron County
* Hunts Corners, New York State, USA; a hamlet in Clarence township, Erie County
* Hunts Corner, New York State, USA; a hamlet in Tusten township, Sullivan County
# Maiden (disambiguation)

A maiden is a male or female virgin.
Maiden or Maidens may also refer to:

## Meaning "first"

* Maiden flight, the first flight by an aircraft
* Maiden name, the family name carried by a woman before marriage
* Maiden over, in the sport of cricket, an over in which no runs are scored
* Maiden race, the first race for a horse
* Maiden race horse, a race horse that has yet to win a race
* Maiden speech, the first speech made by a politician in a formal assembly

## Arts, entertainment, and media

* Iron Maiden, a British heavy metal band, often shortened to "Maiden"
* Maiden, the first of the three aspects of the Triple Goddess (Neopaganism)
* Maiden, the author abbreviation for Joseph Maiden
* MaiDen, the alternative name of the fictional supercouple AlDub on a Philippine TV show
* Maiden (film), a documentary film by Alex Holmes
* The Maiden (film), 2022 Canadian drama film
* Maiden, a survival horror short video game made as a demo for Resident Evil Village

## People with the surname

* David Maiden, Scottish rugby league player
* Gregor Maiden (born 1979), Scottish cricketer
* Jennifer Maiden (born 1949), Australian poet and novelist
* Joe Maiden, author and BBC Radio presenter
* Joseph Maiden (1859–1925), English/Australian botanist
* Michael Maidens (1987–2007), English footballer
* Sidney Maiden (1917–c.1987), American country blues musician
* Willie Maiden (1928–1976), American jazz saxophonist and arranger

## Places

* Mai-den Hall, Kumano Taisha, Matsue, Shimane, Japan

### United Kingdom

* Maiden Bradley, Wiltshire
* Maiden Island, Oban Bay, Scotland
* Maiden Law, Durham, England
* Maiden Moor, in the Lake District of England
* Maiden Newton, Dorset
* Maiden Stack, Shetland
* Maiden Stone, Pictish standing stone near Inverurie, Scotland
* Maiden Wells, Pembrokeshire
* Maidens, South Ayrshire, Scotland
* Maiden's Green, Berkshire
* The Maidens, Northern Ireland
** The Maidens lighthouses

### United States

* Maiden, North Carolina, in Catawba County
* Maiden Creek, a tributary of the Schuylkill River, Pennsylvania
* Maiden Rock, Wisconsin
* Maidens, Virginia

## Other uses

* Maiden (guillotine), a device used for executions
* Maiden (yacht), an ocean racing yacht
* Maiden Holdings, a Bermuda insurance holding company
* Maiden rocksnail (Leptoxis formosa), an extinct freshwater snail species
# Mountain View, Ontario

Mountain View is a small community located in Prince Edward County, Ontario located south of Belleville. Mountain View is the location of a former British Commonwealth Air Training Plan air station which is now known as Canadian Forces Detachment Mountain View (CFD Mountain View), a detachment of CFB Trenton.
# JWM

JWM may refer to:
* Waco JWM, a straight-wing model based on the ASO
* JWM Partners, a hedge fund started in 1998
* Jacksonville Women's Movement, the origin of the Hubbard House, a not-for-profit 501(c)3 entity
# Vladimir Shayslamov

Vladimir Shayslamov (born July 23, 1970) is an Uzbekistani sprint canoer who competed in the mid-1990s. At the 1996 Summer Olympics in Atlanta, paired with his twin brother Sergey Shayslamov, he was eliminated in the repechages of the C-2 500 m event and the semifinals of the C-2 1000 m event.
# Meppen, Illinois

Meppen is an unincorporated community in Calhoun County, Illinois, United States. Meppen is north of Brussels. St. Joseph's Cemetery is located in Meppen.

## History

The community was named after the city of Meppen in the Northwest of Germany.

## Notable person

* Roman Catholic Bishop Victor Hermann Balke was born in Meppen.
# Mitochondrial ribosomal protein L10

39S ribosomal protein L10, mitochondrial is a protein that in humans is encoded by the MRPL10 gene.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified two transcript variants that encode different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q.
# Joy Junction (charity)

Joy Junction is a 501(c)(3) Christian-based homeless shelter and church ministry that offers emergency and short-term essentials such as food, clothing, counseling, transportation, and shelter to homeless individuals and families throughout Albuquerque, New Mexico. Joy Junction's motto is "giving the homeless a Hand Up, not a handout, to help them get back on their feet." Joy Junction opened in 1986 and has become the largest homeless shelter in New Mexico.

## Founder

Joy Junction was founded by Dr. Jeremy Reynalds, who immigrated from England to the United States in 1978, in 1986. He was born in England and immigrated to the United States in 1978, where he himself was homeless for a time. He passed away in 2018, but his work continues at Joy Junction.

## Organization and service to the homeless

Joy Junction's goal is to provide for the basic physical and spiritual needs of the homeless in Albuquerque. However, some neighborhoods have requested that the shelter's mobile truck not operate in their area. On average, Joy Junction serves as many as 300 people per day, including as many as 60 to 80 children; over 16,000 meals are provided to the homeless in Albuquerque every month, and 200,000 every year. A thrift shop was also added in 2023.
During the 2020 COVID-19 pandemic, their shelter accommodated an estimated 300 individuals nightly. They also provided private transportation, as an alternative for public transposition.

## Funding

Joy Junction relies on donations from individuals and businesses throughout New Mexico. Because Joy Junction is a non-profit donations-only charitable organization, the ministry receives no federal, state, or local government funding. The program is mainly funded through donations from individuals, businesses, and churches in the local area. Joy Junction also hosts public events to aid with its funding, such as the 2023 Halloween "Trick-or-Treat So Others May Eat" program, which encourages the donation of canned goods.
# Hydrodyne

Hydrodyne was a boat company founded by Abner Crosby in the late 1950s. The company was then later run by his son Abner (Ab) Crosby Jr. until 1993 when he sold his interest in the company to private investors. The Hydrodyne trademark is owned by another ski boat manufacturer and may one day reappear on boats. At the current time, the use of the name for marine applications is non-existent.
Hydrodyne produced many different hulls, ranging from small runabouts all the way up to house boats. Hydrodyne is mostly remembered for its signature waterskiing boats produced in both twin outboards and inboard/outboard configurations that were the preferred waterskiing boats (along with Ski Nautique and MasterCraft) used in most waterski tournaments and shows throughout the 1960s through the 1990s. A few manufacturers, specifically Tom Miller Boats and Dyna-Ski boat company, still make the 18 foot and 20 foot models that can accept up to 3 outboard motors.
# Metaphors of a Magnifico

"Metaphors of a Magnifico" is a poem from Wallace Stevens's first book of poetry, Harmonium (1923). It was first published in 1918, so it is in the public domain. The poem experiments with perspective.
   Twenty men crossing a bridge, Into a village, Are twenty men crossing twenty bridges, Into twenty villages, Or one man Crossing a single bridge into a village.
   This is old song That will not declare itself ...
   Twenty men crossing a bridge, Into a village, Are Twenty men crossing a bridge Into a village.
   That will not declare itself Yet is certain as meaning ...
   The boots of the men clump On the boards of the bridge. The first white wall of the village Rises through fruit-trees. Of what was it I was thinking? So the meaning escapes.
   The first white wall of the village ... The fruit-trees ...
It explores the difference between detached reportage in its various foci: twenty men, a single bridge, a village; twenty villages; or one man, one bridge, one village, on one hand and immediate lived experience – the boots, the boards, the first white wall of the village rising through the first fruit trees on the other. Stevens' preference for immediate lived experience addressed in his scornful treatment of William Carlos Williams in "Nuances of a Theme by Williams", is what commentators have in mind when they speak of his sensualism. Magnifico may be one of those men crossing the bridge, shifting from viewing himself and the world from various external perspectives to the first-person viewpoint ("Of what was it I was thinking"?). What explicitly will not declare itself is subjective experience, and yet it declares itself through the action of the poem. The meanings that enable objective description of the world do not declare themselves, and yet the poem ends with them in a reduction that is an usurpation of the subjective.
Buttel cites the poem to support his claim that Stevens has the Cubists' ability to see different perspectives of an object simultaneously: "One must assimilate the multiplicity here", he writes about the various bridge crossings, "just as the viewer of Duchamp's painting must assimilate the fragmentation and multiplicity of the nude descending the staircase".
See also his poems "The Snow Man" and "Gubbinal" for related experiments in perspective.
# Orcuttia inaequalis

Orcuttia inaequalis is a rare species of grass known by the common name San Joaquin Valley Orcutt grass.

## Distribution

It is endemic to the Central Valley of California, where it grows only in vernal pools, a rare and declining type of habitat. Many known occurrences of the plant have been extirpated as land in the heavily agricultural Central Valley has been altered, and it was federally listed as a threatened species in 1997.

## Description

Orcuttia inaequalis is a small, hairy, gray-green annual bunchgrass forming tufts or mats up to about 15 centimeters tall. The fluffy, clustered inflorescence is a dense, headlike mass of spikelets, the characteristic that separates this Orcutt grass from the others, which have more spreading inflorescences.
# List of the member committees of the Association of European Rarities Committees

The following is a list of the European rarities committees and equivalent bodies which comprise the membership of the Association of European Rarities Committees (AERC):
* The Avifaunistische Kommission (Austria)
* The Belarus Ornitho-Faunistic Commission (Belarus)
* The Commission d'Homologation (Belgium - Wallonia) and the Belgische Avifaunistische Homologatiecommissie (Belgium - Flanders)
* BUNARCO and the Bulgarian Society for the protection of Birds (Bulgaria)
* The Cyprus Rarities Committee (Cyprus)
* The Czech Faunistic Committee (Czech Republic)
* Sjaldenhedsudvalget (Denmark)
* Eesti Linnuharulduste Komisjon (Estonia)
* Suomen Lintutieteellisen Yhdistyksen Rariteettikomitea (Finland)
* Comite d'Homologation National and Commission de l'Avifaune Française (France)
* The Deutsche Seltenheitenkommission (Germany)
* The British Birds Rarities Committee and the British Ornithologists' Union Records Committee (Great Britain)
* George Handrinos (Greece)
* The Hungarian Rarities Committee (Hungary)
* Flækingsfuglanefndin (Iceland)
* The Irish Rare Birds Committee (Republic of Ireland)
* The Comitato di Omologazione Italiano (Italy)
* Latvijas Ornithofaunistikas Komisijas (Latvia)
* Lithuanian Raritie Commitie (Lietuvos ornitofaunistinė komisija) (Lithuania)
* The Luxemburger Homologations-Kommission (Luxembourg)
* Birdlife Malta (Malta)
* The Commissie Dwaalgasten Nedelerlandse Avifauna (Netherlands)
* The Norsk Sjeldenhetskomite for Fugle (Norway)
* The Komisja Faunistyczna (Poland)
* The Comité Português de Raridades (Portugal)
* The Societatea Ornitologica Româna (Romania)
* The Slovenska Ornithologicka Spolocnost (Slovakia)
* The Bird Watching & Bird Study Association of Slovenia (Slovenia)
* The Comite de Rarezas de SEO (Spain)
* The Sveriges Ornitologiska Förenings Raritetskommitte (Sweden)
* The Schweizerische Avifaunistische Kommission (Switzerland)
* The Ukrainian Avifaunistic Commission (Ukraine)
# Vitaral Jelfa Jelenia Góra

MKS Karkonosze Jelenia Góra is a Polish women's handball team, based in Jelenia Góra.
# Mitochondrial outer membrane permeabilization

Mitochondrial outer membrane permeabilization (MOMP), also known as the mitochondrial outer membrane permeability, is one of two ways apoptosis (a type of programmed cell death) can be activated. It is part of the intrinsic pathway of apoptosis, also known as the mitochondrial pathway. MOMP is known as the point of no return in apoptosis. Once triggered, it results in the diffusion of proteins from the space between the inner and outer mitochondrial membranes into the cytosol.

## Mechanism

Initiation of MOMP involves Bcl-2 family proteins, including BAX and BAK. The outer mitochondrial membrane, typically permeable to molecules smaller than 5 kDa, forms pores during MOMP that allow it to accommodate proteins larger than 100 kDa. During MOMP, it takes about five minutes for all mitochondrial membranes within a cell to permeabilize.

## Outcome

MOMP has been referred to as the point of no return for apoptosis, almost always resulting in the completion of the process, and thus, cell death. However, in limited circumstances, apoptosis does not complete. Sometimes, MOMP does not complete, known as incomplete MOMP (iMOMP) or minority MOMP (miniMOMP). For incomplete MOMP, mitochondrial membranes become permeable in most, but not all, the cell's mitochondria. In minority MOMP, only a few mitochondria of the cell experience MOMP—the result of sublethal stress.
# Functional brigade

A functional brigade —or functional support brigade— is a brigade of the United States Army.
It specialized in combat support or combat service support for a particular military role. The primary purpose of a functional brigade is to conduct operational or theater level tasks or support by "plugging" into operational formations at the theater level or those commanded by corps or division commanders performing as the Army Service Component Command (ASCC) once deployed. Functional brigades, like modular support brigades, have a modular subordinate structure that may vary considerably among brigades of the same type. Unlike the modular support brigades, functional brigades typically operate under theater control and depend on theater-level elements for signal and other support. The theater force may task-organize them to corps or division headquarters. Types of functional brigades include:
* air defense
* chemical, biological, radiological and nuclear defense (CBRN)
* engineering
* explosive ordnance disposal (EOD)
* intelligence
* medical
* military police
* missile defense
* signal
# Hypenodes anatolica

Hypenodes anatolica is a species of moth in the family Erebidae. It was described by Leo Schwingenschuss in 1938. It is found in Bulgaria, Greece, North Macedonia and Turkey.
# Naruto (disambiguation)

Naruto is a Japanese manga series.
Naruto or Narutō may also refer to:
* Naruto (TV series), a Japanese animated television series based on the manga series
* Naruto Uzumaki, the protagonist of the manga and anime series

## Places

* 94356 Naruto, a main-belt asteroid
* Narutō, Chiba, a former town in Chiba Prefecture, Japan
* Naruto, Tokushima, a city in Tokushima Prefecture, Japan
** Naruto Strait, between Awaji Island and Naruto city, Shikoku, Japan
*** Naruto whirlpools, tidal whirlpools in the Naruto Strait

### Facilities and structures

* Naruto University of Education, a national university located in Naruto, Tokushima
* Naruto Athletic Stadium, a multi-purpose stadium in Naruto, Tokushima
* Naruto Line, a railway line in Tokushima Prefecture, Japan
* Naruto Station, a train station in Naruto, Tokushima Prefecture, Japan
* Narutō Station, a train station in Sanmu, Chiba Prefecture, Japan
* Ōnaruto Bridge, connecting Awaji Island and Naruto city in Shikoku

## People, figures, characters

* Naruto (toshiyori), sumo elder
* Naruto, a macaque in the monkey selfie copyright dispute
* Naruto, a character in Cosmic Carnage

## Other uses

* Narutomaki, a kind of kamaboko, or cured fish product
* Naruto stable (2017), a stable of sumo wrestlers