# 2021 Copa Colsanitas – Singles

Camila Osorio defeated Tamara Zidanšek in the final, 5–7, 6–3, 6–4 to win the singles tennis title at the 2021 Copa Colsanitas. It was the Colombian teenage wildcard's first WTA Tour singles title. Ranked No. 180, Osorio became the lowest-ranked WTA title holder since world No. 299 Margarita Gasparyan at the 2018 Tashkent Open. Zidanšek was also in contention for her first WTA title.
Amanda Anisimova was the reigning champion from when the tournament was last held in 2019, but chose to compete in Charleston instead.

## Seeds

* Zheng Saisai (second round)
* Sara Sorribes Tormo (first round)
* Arantxa Rus (second round)
* Clara Tauson (first round)
* Tamara Zidanšek (final)
* Jasmine Paolini (second round)
* Tereza Martincová (second round)
* Wang Yafan (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| WC | Camila Osorio | 6 | 6 | | | | | |
| Q | Harmony Tan | 1 | 2 | | | | | |
| Q | Harmony Tan | 1 | 2 | WC | Camila Osorio | 5 | 6 | 6 |
| | | | | 5 | Tamara Zidanšek | 7 | 3 | 4 |
| | Viktoriya Tomova | 3 | 5 | 5 | Tamara Zidanšek | 7 | 3 | 4 |
| 5 | Tamara Zidanšek | 6 | 7 | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | S Zheng | 6 | 6 | | | | | | | | | | | | | | |
| | UM Arconada | 3 | 1 | | 1 | S Zheng | 4 | 1 | | | | | | | | | |
| | S Vögele | 3 | 6 | 6 | | S Vögele | 6 | 6 | | | | | | | | | |
| Q | C Paquet | 6 | 1 | 4 | | | | | | | S Vögele | 3 | 5 | | | | |
| WC | C Osorio | 6 | 6 | | | | | | | WC | C Osorio | 6 | 7 | | | | |
| | S Vickery | 3 | 2 | | WC | C Osorio | 6 | 6 | | | | | | | | | |
| | L Küng | 6 | 4 | 4 | 7 | T Martincová | 3 | 3 | | | | | | | | | |
| 7 | T Martincová | 4 | 6 | 6 | | | | | | | | | | WC | C Osorio | 6 | 6 |
| 4 | C Tauson | 6 | 3 | 2 | | | | | | | | | | Q | H Tan | 1 | 2 |
| Q | D Seguel | 3 | 6 | 6 | Q | D Seguel | 4 | 6$^3$ | | | | | | | | | |
| | M Buzărnescu | 3 | 3 | | Q | H Tan | 6 | 7$^7$ | | | | | | | | | |
| Q | H Tan | 6 | 6 | | | | | | | Q | H Tan | 6 | 6 | | | | |
| Q | L Arruabarrena | 6 | 6 | | | | | | | Q | L Arruabarrena | 1 | 4 | | | | |
| WC | J Plazas | 0 | 1 | | Q | L Arruabarrena | 2 | 6 | 6 | | | | | | | | |
| | K Ahn | 3 | 0 | | 6 | J Paolini | 6 | 4 | 2 | | | | | | | | |
| 6 | J Paolini | 6 | 6 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 8 | Y Wang | 6 | 5 | 7 | | | | | | | | | | | | | | |
| WC | E Arango | 4 | 7 | 5 | 8 | Y Wang | 3 | 3 | | | | | | | | | | |
| | A-L Friedsam | 2 | 3 | | | V Tomova | 6 | 6 | | | | | | | | | | |
| | V Tomova | 6 | 6 | | | | | | | | V Tomova | 5 | 6 | 6 | | | | |
| | C Bucșa | 3 | 2 | | | | | | | Q | N Párrizas Díaz | 7 | 2 | 4 | | | | |
| Q | N Párrizas Díaz | 6 | 6 | | Q | N Párrizas Díaz | 7$^7$ | 2 | 6 | | | | | | | | | |
| | I Bara | 4 | 7 | 4 | 3 | A Rus | 6$^4$ | 6 | 1 | | | | | | | | | |
| 3 | A Rus | 6 | 5 | 6 | | | | | | | | | | | | V Tomova | 3 | 5 |
| 5 | T Zidanšek | 6 | 7 | | | | | | | | | | | | 5 | T Zidanšek | 6 | 7 |
| | A Kalinskaya | 0 | 5 | | 5 | T Zidanšek | 6 | 6 | | | | | | | | | | |
| | A Sharma | 6 | 5 | 1 | Q | G Gatto-Monticone | 2 | 3 | | | | | | | | | | |
| Q | G Gatto-Monticone | 4 | 7 | 6 | | | | | | 5 | T Zidanšek | 6 | 6 | | | | | |
| | AK Schmiedlová | 4 | 6 | 1 | | | | | | | S Errani | 3 | 4 | | | | | |
| | A Bolsova | 6 | 3 | 6 | | A Bolsova | 4 | 4 | | | | | | | | | | |
| | S Errani | 7 | 7 | | | S Errani | 6 | 6 | | | | | | | | | | |
| 2 | S Sorribes Tormo | 5 | 5 | | | | | | | | | | | | | | | |

## Qualifying
### Seeds

* Arina Rodionova (first round)
* Lara Arruabarrena (qualified)
* Giulia Gatto-Monticone (qualified)
* Nuria Párrizas Díaz (qualified)
* Clara Burel (first round)
* Chloé Paquet (qualified)
* Harmony Tan (qualified)
* Mariam Bolkvadze (first round)
* Robin Anderson (qualifying competition)
* Natalija Kostić (first round)
* Danielle Lao (first round)
* Marina Melnikova (qualifying competition)

### Qualifiers

* Harmony Tan
* Lara Arruabarrena
* Giulia Gatto-Monticone
* Nuria Párrizas Díaz
* Daniela Seguel
* Chloé Paquet

### Draw
#### First qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 1 | Arina Rodionova | 4 | 6$^2$ | | | | | |
| | Dalila Jakupović | 6 | 7$^7$ | | | | | |
| | Dalila Jakupović | 6 | 7$^7$ | | | Dalila Jakupović | 2 | 2 |
| | | | | | 7 | Harmony Tan | 6 | 6 |
| | Yana Sizikova | 1 | 6 | 4 | 7 | Harmony Tan | 6 | 6 |
| 7 | Harmony Tan | 6 | 4 | 6 | | | | |

#### Second qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 2 | Lara Arruabarrena | 6 | 6 | | | | | |
| PR | Carol Zhao | 0 | 0 | | | | | |
| PR | Carol Zhao | 0 | 0 | | 2 | Lara Arruabarrena | 6 | 6 |
| | | | | | WC | Yuliana Monroy | 0 | 0 |
| WC | Yuliana Monroy | 7$^7$ | 2 | 6 | WC | Yuliana Monroy | 0 | 0 |
| 10 | Natalija Kostić | 6$^5$ | 6 | 4 | | | | |

#### Third qualifier

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 3 | Giulia Gatto-Monticone | 6 | 6 | | | | | |
| WC | Kelly Vargas González | 3 | 0 | | | | | |
| WC | Kelly Vargas González | 3 | 0 | 3 | Giulia Gatto-Monticone | 4 | 7 | 6 |
| | | | | | Marie Benoît | 6 | 5 | 3 |
| | Marie Benoît | 6 | 6 | | Marie Benoît | 6 | 5 | 3 |
| 8 | Mariam Bolkvadze | 4 | 0 | | | | | |

#### Fourth qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 4 | Nuria Párrizas Díaz | 4 | 6 | 6 | | | | | |
| WC | Mariana Manyoma | 6 | 3 | 0 | | | | | |
| WC | Mariana Manyoma | 6 | 3 | 0 | 4 | Nuria Párrizas Díaz | 7$^7$ | 4 | 6 |
| | | | | | 12 | Marina Melnikova | 6$^2$ | 6 | 1 |
| | Katarzyna Piter | 5 | 0 | | 12 | Marina Melnikova | 6$^2$ | 6 | 1 |
| 12 | Marina Melnikova | 7 | 6 | | | | | | |

#### Fifth qualifier

| First round | First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition |
| 5 | Clara Burel | 3 | 6 | 4 | | | |
| | Katharina Gerlach | 6 | 1 | 6 | | | |
| | Katharina Gerlach | 6 | 1 | 6 | Katharina Gerlach | 1 | 1 |
| | | | | | Daniela Seguel | 6 | 6 |
| | Daniela Seguel | 6 | 6 | | Daniela Seguel | 6 | 6 |
| 11 | Danielle Lao | 1 | 2 | | | | |

#### Sixth qualifier

| First round | First round | First round | First round | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition | Qualifying competition |
| 6 | Chloé Paquet | 6 | 6 | | | | | |
| WC | Antonia Samudio | 2 | 3 | | | | | |
| WC | Antonia Samudio | 2 | 3 | 6 | Chloé Paquet | 3 | 6 | 6 |
| | | | | 9 | Robin Anderson | 6 | 3 | 2 |
| | Paula Kania-Choduń | 1 | 4 | 9 | Robin Anderson | 6 | 3 | 2 |
| 9 | Robin Anderson | 6 | 6 | | | | | |