# 2022 Morelos Open – Singles

Jurij Rodionov was the defending champion but chose not to defend his title.
Jay Clarke won the title after defeating Adrián Menéndez Maceiras 6–1, 4–6, 7–6$^{(7–5)}$ in the final.

## Seeds

* Ernesto Escobedo (quarterfinals)
* Tim van Rijthoven (first round)
* Jay Clarke (champion)
* Juan Pablo Ficovich (first round)
* Brayden Schnur (first round, retired)
* Nicolás Mejía (second round)
* Yūichi Sugita (first round, retired)
* Rinky Hijikata (semifinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| | Adrián Menéndez Maceiras | 1 | 6 | 6 | | | | | |
| | Chung Yun-seong | 6 | 1 | 4 | | | | | |
| | Chung Yun-seong | 6 | 1 | 4 | | Adrián Menéndez Maceiras | 1 | 6 | 6$^5$ |
| | | | | | 3 | Jay Clarke | 6 | 4 | 7$^7$ |
| 3 | Jay Clarke | 6 | 7 | | 3 | Jay Clarke | 6 | 4 | 7$^7$ |
| 8 | Rinky Hijikata | 2 | 5 | | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | E Escobedo | 6 | 6 | | | | | | | | | | | | | | |
| | D Istomin | 4 | 4 | | 1 | E Escobedo | 7$^7$ | 6 | | | | | | | | | |
| | C Hemery | 6$^{10}$ | 6 | 3 | | P Gunneswaran | 6$^2$ | 4 | | | | | | | | | |
| | P Gunneswaran | 7$^{12}$ | 4 | 6 | | | | | | 1 | E Escobedo | 1 | 6$^3$ | | | | |
| Q | B Lock | 6 | 6 | | | | | | | | A Menéndez Maceiras | 6 | 7$^7$ | | | | |
| | S Mansouri | 4 | 2 | | Q | B Lock | 2 | 3 | | | | | | | | | |
| | A Menéndez Maceiras | 5 | 7$^7$ | 2 | | A Menéndez Maceiras | 6 | 6 | | | | | | | | | |
| 5 | B Schnur | 7 | 6$^3$ | 1$^r$ | | | | | | | | | | A Menéndez Maceiras | 1 | 6 | 6 |
| 4 | JP Ficovich | 6 | 4 | 5 | | | | | | | | | | Y-s Chung | 6 | 1 | 4 |
| | A Kovacevic | 3 | 6 | 7 | | A Kovacevic | 6 | 5 | 4 | | | | | | | | |
| | B Tomic | 3 | 6 | 4 | | Y-s Chung | 3 | 7 | 6 | | | | | | | | |
| | Y-s Chung | 6 | 3 | 6 | | | | | | | Y-s Chung | 6 | 6 | | | | |
| Q | K Smith | 6 | 6 | | | | | | | Q | K Smith | 1 | 4 | | | | |
| Q | F Sun | 4 | 2 | | Q | K Smith | 7 | 6 | | | | | | | | | |
| WC | A Hernández | 6 | 3 | | WC | A Hernández | 5 | 4 | | | | | | | | | |
| 7 | Y Sugita | 3 | 1$^r$ | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 6 | N Mejía | 6 | 6 | | | | | | | | | | | | | | |
| | FC Jianu | 4 | 3 | | 6 | N Mejía | 4 | 6$^5$ | | | | | | | | | |
| WC | Rodolfo Jauregui Sainz de Rozas | 2 | 2 | | | R Quiroz | 6 | 7$^7$ | | | | | | | | | |
| | R Quiroz | 6 | 6 | | | | | | | | R Quiroz | 3 | 4 | | | | |
| Q | Elmar Ejupovic | 6 | 0 | | | | | | | 3 | J Clarke | 6 | 6 | | | | |
| | G Oliveira | 3 | 0$^r$ | | Q | E Ejupovic | 7$^7$ | 3 | 6$^4$ | | | | | | | | |
| | V Durasovic | 4 | 7 | 3 | 3 | J Clarke | 6$^3$ | 6 | 7$^7$ | | | | | | | | |
| 3 | J Clarke | 6 | 5 | 6 | | | | | | | | | | 3 | J Clarke | 6 | 7 |
| 8 | R Hijikata | 6 | 6 | | | | | | | | | | | 8 | R Hijikata | 2 | 5 |
| WC | R Pacheco Méndez | 3 | 2 | | 8 | R Hijikata | 6 | 6 | | | | | | | | | |
| | M Jaziri | 5 | 6 | 7$^7$ | | M Jaziri | 0 | 2 | | | | | | | | | |
| | P Krstin | 7 | 1 | 6$^2$ | | | | | | 8 | R Hijikata | 6 | 6 | | | | |
| Q | N Nakagawa | 2 | 1 | | | | | | | | S Diez | 0 | 1 | | | | |
| | S Diez | 6 | 6 | | | S Diez | 7$^7$ | 6 | | | | | | | | | |
| Q | S Mochizuki | 2 | 7$^7$ | 6 | Q | S Mochizuki | 6$^2$ | 3 | | | | | | | | | |
| 2 | T van Rijthoven | 6 | 6$^2$ | 4 | | | | | | | | | | | | | |