# 2018 Challenger Ciudad de Guayaquil – Singles

Gerald Melzer was the defending champion but lost in the first round to Federico Coria.
Guido Andreozzi won the title after defeating Pedro Sousa 7–5, 1–6, 6–4 in the final.

## Seeds

* Pablo Cuevas (quarterfinals)
* Federico Delbonis (withdrew)
* Guido Andreozzi (champion)
* Christian Garín (withdrew)
* Paolo Lorenzi (second round)
* Thiago Monteiro (first round)
* Hugo Dellien (second round)
* Juan Ignacio Londero (quarterfinals)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final | Final |
| | Arthur De Greef | 5 | 2 | | | | | |
| | Pedro Sousa | 7 | 6 | | | | | |
| | Pedro Sousa | 7 | 6 | | Pedro Sousa | 5 | 6 | 4 |
| | | | | 3 | Guido Andreozzi | 7 | 1 | 6 |
| 3 | Guido Andreozzi | 6 | 7$^{10}$ | 3 | Guido Andreozzi | 7 | 1 | 6 |
| PR | Santiago Giraldo | 4 | 6$^8$ | | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals |
| 1 | P Cuevas | 6 | 6 | | | | | | | | | | | | | |
| WC | D Hidalgo | 3 | 0 | | 1 | P Cuevas | 6 | 2 | 6 | | | | | | | |
| | G Melzer | 2 | 4 | | Q | F Coria | 4 | 6 | 1 | | | | | | | |
| Q | F Coria | 6 | 6 | | | | | | | 1 | P Cuevas | 5 | 3 | | | |
| | DE Galán | 4 | 0 | | | | | | | | A De Greef | 7 | 6 | | | |
| | A De Greef | 6 | 6 | | | A De Greef | 6 | 6 | | | | | | | | |
| WC | J Hernández-Fernández | 6 | 7$^7$ | | WC | J Hernández-Fernández | 0 | 4 | | | | | | | | |
| 6 | T Monteiro | 1 | 6$^2$ | | | | | | | | | | | A De Greef | 5 | 2 |
| LL | U Blanch | 7 | 6 | | | | | | | | | | | P Sousa | 7 | 6 |
| | F Bagnis | 5 | 4 | | LL | U Blanch | 4 | 1 | | | | | | | | |
| | F Argüello | 4 | 6 | 6 | | F Argüello | 6 | 6 | | | | | | | | |
| | G Clezar | 6 | 2 | 1 | | | | | | | F Argüello | 6$^6$ | 3 | | | |
| WC | N Álvarez | 4 | 4 | | | | | | | | P Sousa | 7$^8$ | 6 | | | |
| | P Sousa | 6 | 6 | | | P Sousa | 4 | 6 | 6 | | | | | | | |
| Q | T Seyboth Wild | 6 | 3 | 4 | 7 | H Dellien | 6 | 1 | 4 | | | | | | | |
| 7 | H Dellien | 3 | 6 | 6 | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5 | P Lorenzi | 6 | 6$^6$ | 7$^7$ | | | | | | | | | | | | | | |
| Q | M Cuevas | 4 | 7$^8$ | 6$^5$ | 5 | P Lorenzi | 6$^6$ | 2 | | | | | | | | | | |
| | P Krstin | 6 | 7$^7$ | | | P Krstin | 7$^8$ | 6 | | | | | | | | | | |
| | R Cid Subervi | 3 | 6$^3$ | | | | | | | | P Krstin | 4 | 2 | | | | | |
| WC | E Gómez | 2 | 6 | 4 | | | | | | 3 | G Andreozzi | 6 | 6 | | | | | |
| | T Bellucci | 6 | 3 | 6 | | T Bellucci | 3 | 2 | | | | | | | | | | |
| | C Berlocq | 6$^6$ | 2 | | 3 | G Andreozzi | 6 | 6 | | | | | | | | | | |
| 3 | G Andreozzi | 7$^8$ | 6 | | | | | | | | | | | | 3 | G Andreozzi | 6 | 7$^{10}$ |
| 8 | JI Londero | 6 | 6 | | | | | | | | | | | | PR | S Giraldo | 4 | 6$^8$ |
| | L Giustino | 2 | 4 | | 8 | JI Londero | 6$^5$ | 7$^9$ | 6 | | | | | | | | | |
| Q | JP Varillas | 3 | 6 | 3 | | R Quiroz | 7$^7$ | 6$^7$ | 1 | | | | | | | | | |
| | R Quiroz | 6 | 3 | 6 | | | | | | 8 | JI Londero | 7 | 6$^3$ | 6$^7$ | | | | |
| PR | S Giraldo | 7 | 6 | | | | | | | PR | S Giraldo | 5 | 7$^7$ | 7$^9$ | | | | |
| | J Domingues | 5 | 3 | | PR | S Giraldo | 7 | 7 | | | | | | | | | | |
| | G Elias | 6$^3$ | 6 | 1 | LL | M Zekić | 5 | 5 | | | | | | | | | | |
| LL | M Zekić | 7$^7$ | 0 | 6 | | | | | | | | | | | | | | |