# 2021 Grand Est Open 88 – Singles

Katarina Zavatska was the defending champion but chose not to participate.
Anhelina Kalinina won the title, defeating Dalma Gálfi in the final, 6–2, 6–2.

## Seeds

* Martina Trevisan (first round)
* Océane Dodin (quarterfinals)
* Stefanie Vögele (first round)
* Anhelina Kalinina (champion)
* Réka Luca Jani (first round)
* Zheng Qinwen (semifinals)
* Jana Fett (second round, retired)
* Dalma Gálfi (final)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| | Amandine Hesse | 6$^3$ | 4 | | | | |
| 8 | Dalma Gálfi | 7$^7$ | 6 | | | | |
| 8 | Dalma Gálfi | 7$^7$ | 6 | 8 | Dalma Gálfi | 2 | 2 |
| | | | | 4 | Anhelina Kalinina | 6 | 6 |
| 4 | Anhelina Kalinina | 6 | 6 | 4 | Anhelina Kalinina | 6 | 6 |
| 6 | Zheng Qinwen | 4 | 4 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | M Trevisan | 6 | 3 | 2 | | | | | | | | | | | | |
| Q | O Selekhmeteva | 1 | 6 | 6 | Q | O Selekhmeteva | 6$^5$ | 1 | | | | | | | | |
| | A Hesse | 6 | 6 | | | A Hesse | 7$^7$ | 6 | | | | | | | | |
| Q | É Dartron | 2 | 1 | | | | | | | A Hesse | 6 | 6 | | | | |
| Q | K Bartone | 6 | 3 | | | | | | Q | K Bartone | 2 | 1 | | | | |
| | I Fetecău | 3 | 0$^r$ | | Q | K Bartone | 6 | 2 | | | | | | | | |
| Q | V Strakhova | 0 | 7$^7$ | 5 | 7 | J Fett | 1 | 1$^r$ | | | | | | | | |
| 7 | J Fett | 6 | 6$^4$ | 7 | | | | | | | | | | A Hesse | 6$^3$ | 4 |
| 3 | S Vögele | 2 | 4 | | | | | | | | | | 8 | D Gálfi | 7$^7$ | 6 |
| Q | L Jeanjean | 6 | 6 | | Q | L Jeanjean | 6 | 6 | | | | | | | | |
| | J Loeb | 4 | 1 | | | A Danilina | 2 | 4 | | | | | | | | |
| | A Danilina | 6 | 6 | | | | | | Q | L Jeanjean | 1 | 0 | | | | |
| | U Eikeri | 4 | 6 | 4 | | | | | 8 | D Gálfi | 6 | 6 | | | | |
| | E Kostova | 6 | 3 | 6 | | E Kostova | 6$^2$ | 1 | | | | | | | | |
| WC | M Partaud | 1 | 4 | | 8 | D Gálfi | 7$^7$ | 6 | | | | | | | | |
| 8 | D Gálfi | 6 | 6 | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 5 | RL Jani | 2 | 7$^7$ | 4 | | | | | | | | | | | | | | |
| WC | E Jacquemot | 6 | 6$^4$ | 6 | WC | E Jacquemot | 6 | 5 | 6 | | | | | | | | | |
| Q | W Falkowska | 0 | 3 | | PR | Y Yuan | 2 | 7 | 1 | | | | | | | | | |
| PR | Y Yuan | 6 | 6 | | | | | | | WC | E Jacquemot | 7$^9$ | 0 | 1 | | | | |
| | J Pieri | 4 | 1 | | | | | | | 4 | A Kalinina | 6$^7$ | 6 | 6 | | | | |
| WC | L Boisson | 6 | 6 | | WC | L Boisson | 2 | 1 | | | | | | | | | | |
| | D Seguel | 7$^7$ | 2 | 4 | 4 | A Kalinina | 6 | 6 | | | | | | | | | | |
| 4 | A Kalinina | 6$^4$ | 6 | 6 | | | | | | | | | | | 4 | A Kalinina | 6 | 6 |
| 6 | Q Zheng | 7 | 7$^7$ | | | | | | | | | | | | 6 | Q Zheng | 4 | 4 |
| | M Yerolymos | 5 | 6$^2$ | | 6 | Q Zheng | 7$^7$ | 6 | | | | | | | | | | |
| | A Hartono | 3 | 6 | 1 | | YL Miyazaki | 6$^3$ | 2 | | | | | | | | | | |
| | YL Miyazaki | 6 | 2 | 6 | | | | | | 6 | Q Zheng | 6 | 6 | | | | | |
| Q | L Papadakis | 4 | 2 | | | | | | | 2 | O Dodin | 2 | 1 | | | | | |
| Q | M Rouvroy | 6 | 6 | | Q | M Rouvroy | 4 | 2 | | | | | | | | | | |
| WC | L Wargnier | 5 | 3 | | 2 | O Dodin | 6 | 6 | | | | | | | | | | |
| 2 | O Dodin | 7 | 6 | | | | | | | | | | | | | | | |