# 2021 Vesuvio Cup – Singles

This was the first edition of the tournament.
Tallon Griekspoor won the title after defeating Alexander Ritschard 6–3, 6–2 in the final.

## Seeds

* Federico Coria (second round)
* Marco Cecchinato (second round)
* Hugo Gaston (first round)
* Alex Molčan (withdrew)
* Tallon Griekspoor (champion)
* Andrej Martin (second round)
* Bernabé Zapata Miralles (quarterfinals)
* Yannick Hanfmann (second round)

## Draw
### Key

* Q = Qualifier
* WC = Wild card
* LL = Lucky loser
* Alt = Alternate
* SE = Special exempt
* PR = Protected ranking
* ITF = ITF entry
* JE = Junior exempt
* w/o = Walkover
* r = Retired
* d = Defaulted
* SR = Special ranking

### Finals

| Semifinals | Semifinals | Semifinals | Semifinals | Final | Final | Final | Final |
| 5 | Tallon Griekspoor | 6 | 6 | | | | |
| | Flavio Cobolli | 4 | 4 | | | | |
| | Flavio Cobolli | 4 | 4 | 5 | Tallon Griekspoor | 6 | 6 |
| | | | | Q | Alexander Ritschard | 3 | 2 |
| | Franco Agamenone | 3 | 3 | Q | Alexander Ritschard | 3 | 2 |
| Q | Alexander Ritschard | 6 | 6 | | | | |

### Top half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 1 | F Coria | 6 | 6 | | | | | | | | | | | | | | | |
| Alt | A Arnaboldi | 4 | 2 | | 1 | F Coria | 2 | 2 | | | | | | | | | | |
| WC | J Berrettini | 5 | 7$^7$ | 4 | | M Guinard | 6 | 6 | | | | | | | | | | |
| | M Guinard | 7 | 6$^5$ | 6 | | | | | | | M Guinard | 6$^7$ | 6 | 3 | | | | |
| Q | Á López San Martín | 6 | 6 | | | | | | | 5 | T Griekspoor | 7$^9$ | 3 | 6 | | | | |
| | T Skatov | 3 | 2 | | Q | Á López San Martín | 3 | 3 | | | | | | | | | | |
| | B Rola | 2 | 6$^6$ | | 5 | T Griekspoor | 6 | 6 | | | | | | | | | | |
| 5 | T Griekspoor | 6 | 7$^8$ | | | | | | | | | | | | 5 | T Griekspoor | 6 | 6 |
| LL | E Furness | 1 | 1 | | | | | | | | | | | | | F Cobolli | 4 | 4 |
| WC | M Arnaldi | 6 | 6 | | WC | M Arnaldi | 1 | 6 | 2 | | | | | | | | | |
| | D Ajduković | 5 | 3 | | | F Cobolli | 6 | 3 | 6 | | | | | | | | | |
| | F Cobolli | 7 | 6 | | | | | | | | F Cobolli | 6 | 3 | 7 | | | | |
| | L Giustino | 6 | 6 | | | | | | | | L Giustino | 4 | 6 | 5 | | | | |
| | N Serdarušić | 4 | 1 | | | L Giustino | 6 | 5 | 7 | | | | | | | | | |
| | M Bašić | 3 | 6 | 5 | 6 | A Martin | 4 | 7 | 5 | | | | | | | | | |
| 6 | A Martin | 6 | 4 | 7 | | | | | | | | | | | | | | |

### Bottom half

| First round | First round | First round | First round | First round | Second round | Second round | Second round | Second round | Second round | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Quarterfinals | Semifinals | Semifinals | Semifinals | Semifinals |
| 7 | B Zapata Miralles | 6 | 6 | | | | | | | | | | | | | | | |
| | A Pellegrino | 3 | 1 | | 7 | B Zapata Miralles | 7$^7$ | 6 | | | | | | | | | | |
| | A Müller | 6 | 3 | 6 | | A Müller | 6$^0$ | 0 | | | | | | | | | | |
| PR | F Baldi | 1 | 6 | 2 | | | | | | 7 | B Zapata Miralles | 3 | 0 | | | | | |
| | M Bourgue | 6 | 6 | | | | | | | | F Agamenone | 6 | 6 | | | | | |
| Q | L Darderi | 2 | 4 | | | M Bourgue | 7 | 6$^3$ | 1 | | | | | | | | | |
| | F Agamenone | 6 | 2 | 6 | | F Agamenone | 5 | 7$^7$ | 6 | | | | | | | | | |
| 3 | H Gaston | 4 | 6 | 3 | | | | | | | | | | | | F Agamenone | 3 | 3 |
| 8 | Y Hanfmann | 6 | 5 | 6 | | | | | | | | | | | Q | A Ritschard | 6 | 6 |
| WC | R Brancaccio | 4 | 7 | 2 | 8 | Y Hanfmann | 3 | 6 | 4 | | | | | | | | | |
| Q | A Ritschard | 6 | 6 | | Q | A Ritschard | 6 | 4 | 6 | | | | | | | | | |
| | J Clarke | 0 | 1 | | | | | | | Q | A Ritschard | 0 | 7$^7$ | 6 | | | | |
| Q | J Forejtek | 3 | 4 | | | | | | | | GM Moroni | 6 | 6$^1$ | 3 | | | | |
| | GM Moroni | 6 | 6 | | | GM Moroni | 3 | 6 | 6 | | | | | | | | | |
| | M-A Hüsler | 6 | 3 | 2 | 2 | M Cecchinato | 6 | 1 | 4 | | | | | | | | | |
| 2 | M Cecchinato | 4 | 6 | 6 | | | | | | | | | | | | | | |