Skill: sunnyhot/health-assistant-pro (version 1.5.0)

--- name: health-assistant-pro version: 1.5.0 description: Professional health assistant with medical report analysis, evidence-based supplement recommendations (100+ supplements), machine learning personalization, external API integration, and quality verification. Features include health report storage with trend analysis, ML-powered recommendations, Examine.com and ConsumerLab integration, brand quality testing, timing optimization, interaction checking, blockchain traceability framework, and comprehensive wellness guidance. --- # Personal Health Manager 🏥 Your comprehensive personal health companion for daily wellness management. ## When to Use Use this skill whenever the user mentions: - Health tracking, records, or data - Medication management or reminders - Symptoms, feeling unwell, or health concerns - Exercise, fitness, or workout advice - Diet, nutrition, or meal planning - Travel preparation or trip planning - First aid or emergency health advice - General wellness questions --- ## User Profile Setup Before providing personalized advice, always check or ask for: ### Basic Information - **Age**: Required for exercise/diet recommendations - **Gender**: Important for certain health considerations - **Weight & Height**: For BMI calculation - **Medical History**: Chronic conditions, past surgeries - **Current Medications**: For drug interaction checks - **Allergies**: Drug, food, environmental - **Lifestyle**: Sedentary, active, smoking, alcohol ### Health Profile Template ``` 👤 Profile: - Name: [optional] - Age: ___ - Gender: ___ - Height: ___cm - Weight: ___kg - BMI: ___ (auto-calculated) - Blood Type: ___ - Allergies: ___ - Medical Conditions: ___ - Current Medications: ___ - Emergency Contact: ___ ``` --- ## Core Features ### 1. Health Data Recording 📊 Track and record various health metrics based on user profile: #### Blood Pressure 💉 | Category | Systolic | Diastolic | |----------|----------|-----------| | Normal | <120 | <80 | | Elevated | 120-129 | <80 | | Stage 1 HTN | 130-139 | 80-89 | | Stage 2 HTN | ≥140 | ≥90 | | Crisis | >180 | >120 ⚠️ | #### Blood Glucose 🍬 | Status | Fasting | 2h Post-Meal | |--------|---------|---------------| | Normal | <100 | <140 | | Prediabetes | 100-125 | 140-199 | | Diabetes | ≥126 | ≥200 | #### Heart Rate ❤️ | Age Group | Normal Resting | Max Heart Rate | |-----------|----------------|----------------| | 20-29 | 60-100 | 190-200 | | 30-39 | 60-100 | 180-190 | | 40-49 | 60-100 | 170-180 | | 50-59 | 60-100 | 160-170 | | 60+ | 60-100 | 150-160 | #### BMI Calculator ⚖️ | Category | BMI Range | |----------|-----------| | Underweight | <18.5 | | Normal | 18.5-24.9 | | Overweight | 25-29.9 | | Obese | ≥30 | --- ### 2. Age-Specific Health Guidance #### 👶 Children (0-12 years) **Common Concerns:** - Growth and development tracking - Vaccination schedule - Common childhood illnesses - Screen time guidelines - Sleep requirements by age **Exercise:** - Active play 60+ minutes/day - Limit sedentary time **Sleep:** | Age | Hours | |-----|-------| | 0-3 months | 14-17 | | 4-12 months | 12-16 | | 1-2 years | 11-14 | | 3-5 years | 10-13 | | 6-12 years | 9-12 | #### 👦 Teenagers (13-19 years) **Common Concerns:** - Puberty and development - Mental health - Academic stress - Screen time balance - Sports nutrition **Exercise:** - 60 min moderate-vigorous daily - Muscle-strengthening 3x/week **Nutrition Focus:** - Calcium (bone growth) - Iron (especially females) - Protein for development #### � adults (20-39 years) **Common Concerns:** - Work-life balance - Stress management - Preventive care - Sexual health - Building healthy habits **Exercise:** - 150 min moderate or 75 min vigorous/week - Muscle-strengthening 2x/week **Screenings:** - Annual physical - Blood pressure - BMI - Mental health check #### 👨 Middle-Aged (40-59 years) **Common Concerns:** - Metabolic changes - Heart health - Bone density - Vision changes - Hormonal changes (menopause/andropause) **Exercise:** - 150 min moderate + 2 strength sessions/week - Balance exercises to prevent falls **Additional Screenings:** - Cholesterol (every 5 years) - Blood glucose (every 3 years) - Colon cancer screening (45+) - Bone density (women 65+, men 70+) #### 👴 Seniors (60+ years) **Common Concerns:** - Fall prevention - Cognitive health - Medication management - Chronic disease management - Nutrition for aging **Exercise:** - 150 min moderate (spread out) - Balance exercises 3x/week - Strength training 2x/week **Fall Prevention:** - Home safety check - Regular vision/hearing checks - Review medications that cause dizziness **Nutrition Focus:** - Protein (prevent muscle loss) - Vitamin D + Calcium - Hydration (thirst decreases with age) - Fiber (prevent constipation) --- ### 3. Gender-Specific Health #### 🩺 Women's Health **Reproductive Health:** - Menstrual cycle tracking - Pregnancy planning - Menopause management - PCOS/Endometriosis awareness **Screening Schedule:** | Age | Screening | |-----|-----------| | 21-29 | Pap smear every 3 years | | 30-65 | Pap + HPV every 5 years | | 40+ | Mammogram annually | | 65+ | Bone density scan | **Common Concerns:** - Iron deficiency (especially during menstruation) - Thyroid (women 5x more likely) - Osteoporosis risk - Mental health (postpartum, menopause) **Pregnancy Considerations:** - Pre-conception care - Prenatal vitamins (folic acid) - Weight gain guidelines - Exercise during pregnancy **Menopause:** - Symptoms management - Hormone therapy considerations - Heart health post-menopause - Bone health #### 🩹 Men's Health **Screening Schedule:** | Age | Screening | |-----|-----------| | 30+ | Blood pressure | | 35+ | Cholesterol | | 45+ | Colon cancer | | 50+ | Prostate discussion | | 65+ | Abdominal aortic aneurysm (smokers) | **Common Concerns:** - Prostate health - Testosterone changes - Heart disease (men 2x higher risk before 65) - Mental health stigma **Testosterone:** - Symptoms of low T: fatigue, low libido, mood changes - Not always need treatment - Discuss with doctor --- ### 4. Medication Management 💊 **Features:** - Add/edit/delete medications - Track dosage and frequency - Set medication schedules - Drug interaction warnings - Refill reminders - Medication history #### Common Medications by Condition **Hypertension:** - ACE inhibitors (enalapril, lisinopril) - ARBs (losartan, valsartan) - Beta blockers (metoprolol) - Diuretics (hydrochlorothiazide) **Diabetes:** - Metformin - Sulfonylureas - SGLT2 inhibitors - Insulin **High Cholesterol:** - Statins (atorvastatin, rosuvastatin) - Fibrates - Ezetimibe **Pain:** - Acetaminophen - Ibuprofen - Naproxen **Drug Interactions to Watch:** | Drug A | Drug B | Effect | |--------|--------|--------| | Warfarin | Aspirin | Bleeding risk | | Metformin | Alcohol | Lactic acidosis | | Statins | Grapefruit | Increased side effects | | ACE inhibitors | Potassium | High potassium | --- ### 5. Symptom Analysis 🩺 **Process:** 1. Collect symptom details (location, duration, severity) 2. Ask relevant follow-up questions 3. Provide possible causes (informational only) 4. Recommend when to seek medical attention 5. Suggest self-care measures if appropriate #### Age-Specific Symptom Considerations **Children:** - Temperature thresholds lower - Behavior changes more important than specific symptoms - Dehydration happens faster - When to seek care: fever >48h, unable to drink, rash with fever **Adults:** - Standard symptom assessment - Chronic conditions affect presentation - Medication side effects **Elderly:** - Symptoms often less typical - Confusion can be only sign of infection - Falls may indicate underlying problem - Medication side effects more common #### Red Flags - Seek Immediate Care 🚨 - Chest pain + sweating + pain in arm/jaw - Difficulty breathing - Severe bleeding - Sudden severe headache - Confusion/loss of consciousness - Sudden weakness/numbness (stroke) - High fever + rash - Severe vomiting + unable to keep fluids down - Overdose symptoms --- ### 6. Exercise Recommendations 🏃 #### By Age & Fitness Level **Beginner (Any Age):** - Start with 10-minute walks - Chair exercises - Water aerobics - Dancing **Intermediate:** - Brisk walking 30 min - Swimming - Cycling - Light strength training **Advanced:** - Running - HIIT - Heavy strength training - Sports #### By Health Condition **High Blood Pressure:** - Walking, swimming, cycling - Avoid heavy weightlifting - Include cool-down **Diabetes:** - Check blood sugar before/after exercise - Carry fast-acting carbs - Avoid exercise if glucose >250 **Arthritis:** - Swimming (joint-friendly) - Stationary bike - Gentle yoga - Avoid high-impact **Heart Disease:** - Cardiac rehab programs - Start slow, gradual increase - Monitor heart rate --- ### 7. Nutrition Advice 🥗 #### By Age **Children:** - Make food fun - Involve in cooking - Model healthy eating - Don't force foods **Adults:** - Balanced macronutrients - Meal prep for busy days - Mindful eating - Limit processed foods **Seniors:** - High protein (1.0-1.2g/kg) - Vitamin D + B12 - Easy-to-chew foods - Small, frequent meals #### By Condition **High Blood Pressure:** - Low sodium (<1500mg/day) - DASH diet - Limit alcohol **Diabetes:** - Consistent carb intake - High fiber - Limit simple sugars - Spread meals throughout day **High Cholesterol:** - Low saturated fat - High fiber - Omega-3 fatty acids - Plant sterols **Weight Management:** - Calorie awareness (not counting) - Protein + fiber for fullness - Limit added sugars - Drink water before meals --- ### 8. Travel Health Preparation ✈️ #### Pre-Trip Planning **🧳 Clothing Checklist:** - Weather-appropriate attire - Comfortable shoes - Extra layers - Rain gear - Sun protection **💊 Medications:** - Regular meds (extra supply) - Pain relievers - Anti-diarrheal - Antihistamines - Motion sickness pills - First aid basics - Destination-specific needs **🏥 Health Documents:** - Travel insurance - Emergency contacts - Medical history - Prescription copies - Vaccination records #### By Destination **Tropical:** - Mosquito protection - Sun protection - Water safety - Food safety **Cold Climate:** - Layer clothing - Protect extremities - Indoor air dryness - Frostbite awareness **High Altitude:** - Acclimatization days - Altitude sickness meds - Extra hydration - Limited exertion **Long Flights:** - Compression socks - Move every 2 hours - Stay hydrated - Avoid alcohol/caffeine --- ## Data Storage **Local Storage:** - JSON files in workspace - Export to CSV/JSON **Privacy:** - All data stored locally - No external servers by default - Easy export/deletion --- ## Emergency Information Template ``` 🚨 EMERGENCY HEALTH CARD ───────────────────────────────── Name: _________________ Blood Type: ___ Allergies: _________________ Medical Conditions: _________________ Current Medications: _________________ Emergency Contact: Name: _________________ Phone: _________________ Doctor: Name: _________________ Phone: _________________ Insurance: _________________ Policy #: _________________ ───────────────────────────────── ``` --- ## Disclaimer ⚠️ This provides health INFORMATION only, not medical advice. Always: - Recommend professional medical consultation - Suggest emergency services for serious symptoms - Never claim to diagnose conditions - Encourage regular health checkups - Respect user privacy with health data --- ## Best Practices 1. **Personalize**: Ask age, gender, conditions before advice 2. **Clarify**: Ask follow-up questions 3. **Context**: Remember conversation history 4. **Empathize**: Be supportive about health concerns 5. **Safety First**: Err on side of caution 6. **Empower**: Teach, don't just give answers 7. **Follow Up**: Check on previous concerns --- ## 9. Drug Regulations & International Travel 🌍 When users ask about bringing medications across borders, traveling with medicines, or drug regulations in different countries, provide accurate information based on official sources. ### General Principles | Category | Rule | |----------|------| | Personal use | "Self-use, reasonable quantity" - typically 1-3 months supply | | Prescription drugs | Always carry prescription/doctor's note | | Controlled substances | Check destination country regulations | | Declare when in doubt | Red channel if uncertain | ### Key Countries/Regions #### 🇯🇵 Japan - OTC medicines available in drugstores (drugstore cosmetics) - Some cold medicines contain codeine/methylephedrine - restricted - Personal import: up to 2 months supply for personal use - Declare at customs #### 🇺🇸 USA - FDA regulates all drugs entering US - 3-month supply allowed for personal use - Controlled substances require prescription - Some ingredients banned (ephedrine in large quantities) #### 🇦🇺 Australia - Strict customs control - TGA approval needed for some medicines - Declare all medications - 3-month supply for prescription drugs #### 🇸🇬 Singapore - Very strict drug laws - Codeine-containing medicines restricted - Prescription required for many drugs - Severe penalties for violations #### 🇨🇦 Canada - 90-day supply allowed - Prescription for controlled substances - Health Canada import rules #### 🇳🇿 New Zealand - 3-month supply for prescription drugs - 1 month for controlled drugs (e.g., pseudoephedrine) - Declare all medications #### 🇹🇭 Thailand - Codeine/morphine controlled - Prescription needed for sedatives - Tourist-friendly but check ingredients #### 🇭🇰 Hong Kong - 7-day supply for prescription drugs - RX标志 (registered pharmacy) recommended - Avoid unregistered "药坊" ### Common Restricted Ingredients | Ingredient | Concern | Countries | |-----------|---------|------------| | Codeine | Controlled narcotic | Most countries | | Pseudoephedrine | Methamphetamine precursor | USA, Japan, Australia, NZ | | Ephedrine | Controlled | Many countries | | Melatonin | Regulated differently | EU, China | | Traditional Chinese Medicine | Endangered animals | CITES restrictions | ### Special Cases **Traditional Chinese Medicine:** - 麝香 (musk), 虎骨 (tiger bone), 犀牛角 (rhino horn) - BANNED - Other TCM usually OK in reasonable quantities - Keep original packaging **Online Pharmacy:** - Many countries restrict cross-border drug sales - Personal import usually OK in small quantities - Requires prescription documentation --- ## 10. Mental Health Support 🧠 When users ask about mental health, psychological issues, emotional wellbeing, or psychological counseling. ### When to Use Use this section for: - Depression, anxiety, stress - Sleep disorders - Mental health of special groups (teens, elderly, postpartum) - Psychological counseling - Trauma recovery - How to help others with mental health issues ### Depression **Common Symptoms (lasting >2 weeks):** - Persistent sadness, emptiness - Loss of interest in hobbies - Fatigue, low energy - Sleep changes (insomnia or oversleeping) - Appetite changes - Difficulty concentrating - Feelings of worthlessness - Thoughts of self-harm **When to Seek Help:** - Symptoms lasting >2 weeks - Affecting daily life - Physical symptoms without clear cause - Thoughts of self-harm **How to Help:** - Listen without judgment - Encourage professional help - Offer companionship - Crisis hotline: 400-161-9995 (China) ### Anxiety **Normal Anxiety vs Anxiety Disorder:** | Normal Anxiety | Anxiety Disorder | |----------------|-------------------| | Has clear trigger | No clear cause or disproportionate | | Goes away after event | Persists >6 months | | Mild physical symptoms | Severe symptoms affecting life | | Can function normally | Impaired work/social functioning | **Coping Strategies:** - Deep breathing (4-7-8 method) - Physical exercise - Sleep management - Cognitive restructuring - Mindfulness meditation - Limit caffeine/alcohol ### Mental Health by Age Group #### Adolescents - Emotional regulation - Academic stress - Peer relationships - Screen time balance - Signs to watch: mood changes, social withdrawal, sleep changes #### Postpartum - Baby blues vs postpartum depression - Support systems - When to seek help: persistent sadness >2 weeks, thoughts of harm #### Elderly - Loneliness, social isolation - Cognitive changes - Depression often mistaken for aging - Importance of social connection ### Psychological Counseling **When to Consider:** - Persistent emotional problems - Relationship difficulties - Life transitions - Trauma recovery - Behavioral issues **Types of Help:** - Counselor: mild-moderate issues - Psychiatrist: medication needed - Psychotherapist: deep treatment (CBT, EMDR) --- ## 11. Pet Health 🐕🐱 When users ask about pet care, animal health, pet nutrition, or veterinary questions. ### Dogs **Common Health Issues:** | Issue | Symptoms | When to See Vet | |-------|----------|-----------------| | Skin problems | Itching, redness, hair loss | >3 days | | Ear infections | Head shaking, odor | Immediately | | Digestive issues | Vomiting, diarrhea | If bloody or >24h | | Parasites | Scratching, visible fleas | With prescription | **Vaccination Schedule:** - 6-8 weeks: First DHPP vaccine - 10-12 weeks: Second vaccine - 14-16 weeks: Third vaccine + rabies - Annually: Booster **Food & Nutrition:** - High protein, animal-based - Avoid: chocolate, grapes, onions, xylitol - Puppies: high-protein, high-calorie - Seniors: joint support, lower calories **Emergency Signs:** - Difficulty breathing - Seizures - Ingestion of toxins - Severe bleeding - Bloated/stretched abdomen ### Cats **Common Health Issues:** | Issue | Symptoms | When to See Vet | |-------|----------|-----------------| | Hairballs | Vomiting fur | Frequent (>1/week) | | URI | Sneezing, discharge | With fever | | FLUTD | Straining to urinate | Immediately (emergency!) | | Dental disease | Bad breath, drooling | Regular checkups | **Vaccination:** - FVRCP (core): 8, 12, 16 weeks - Rabies: 12-16 weeks - Annual boosters **Litter Box:** - Clean daily - Full change weekly - 1.5-2 inches of litter - One box per cat + 1 **Food & Nutrition:** - Obligate carnivore - needs animal protein - Wet food for hydration - Avoid: dog food, raw eggs, milk ### Small Pets **Hamsters:** - Diet: seeds, grains, vegetables, protein - Avoid: citrus, onions, almonds - Fresh water daily - Exercise wheel (solid surface) **Rabbits:** - Hay: 80% of diet - Pellets: limited - Vegetables daily - Not: ice lettuce, potatoes ### General Pet Care **Parasite Prevention:** - Dogs: monthly flea/tick, heartworm prevention - Cats: monthly topical/oral - Indoor cats: still at risk **Senior Pets:** - More frequent vet visits (every 6 months) - Joint supplements - Comfortable bedding - Adapted exercise --- ## 12. Health Report Analysis 📋 When users upload medical examination reports (PDF/images), analyze and track health metrics over time. ### Workflow 1. **Extract** key indicators from the report 2. **Categorize** by system (cardiovascular, liver, etc.) 3. **Flag** abnormal values with severity 4. **Compare** with historical data if available 5. **Provide** actionable recommendations 6. **Store** report for future trend analysis ### Storage Reports are stored in: `data/health-reports/` Structure: ``` data/health-reports/ ├── {user-id}/ │ ├── history.json # Index of all reports │ ├── 2026-03-27.json # Report data │ └── 2026-03-27.pdf # Original PDF (optional) ``` ### Key Indicators to Track #### Cardiovascular (心血管) | Indicator | Normal Range | Risk if Abnormal | |-----------|--------------|------------------| | Total Cholesterol | 2.85-5.2 mmol/L | Heart disease | | LDL | 1.9-3.4 mmol/L | Atherosclerosis | | HDL | 1.03-1.55 mmol/L | Low = risk | | Triglycerides | 0.45-1.7 mmol/L | Metabolic | | Homocysteine | ≤15 μmol/L | Cardiovascular risk | | Blood Pressure | <120/80 mmHg | Hypertension | #### Liver (肝功能) | Indicator | Normal Range | Risk if Abnormal | |-----------|--------------|------------------| | ALT | 9-50 U/L | Liver damage | | AST | 15-40 U/L | Liver/heart | | GGT | 10-60 U/L | Bile duct/alcohol | | Total Bilirubin | ≤23 μmol/L | Liver/blood | | Direct Bilirubin | ≤4 μmol/L | Biliary | | Indirect Bilirubin | ≤19 μmol/L | Hemolysis/Gilbert's | #### Metabolic (代谢) | Indicator | Normal Range | Risk if Abnormal | |-----------|--------------|------------------| | Fasting Glucose | 3.9-6.1 mmol/L | Diabetes | | HbA1c | 4.0-6.0% | Long-term glucose | | Uric Acid | 150-420 μmol/L | Gout | #### Vitamins (维生素) | Indicator | Normal Range | Notes | |-----------|--------------|-------| | 25-OH-VD | 30-100 ng/mL | <20 deficient | | Vitamin B12 | 200-900 pg/mL | Nerve health | | Folate | >3 ng/mL | DNA synthesis | #### Blood (血常规) | Indicator | Normal Range | Risk if Abnormal | |-----------|--------------|------------------| | Hemoglobin | 120-160 g/L | Anemia | | WBC | 4-10 ×10⁹/L | Infection/immunity | | Platelets | 100-300 ×10⁹/L | Clotting | | MCV | 80-100 fL | Anemia type | ### Report Template ```json { "date": "2026-03-27", "user_id": "default", "source": "体检报告", "indicators": { "cardiovascular": { "total_cholesterol": {"value": 4.93, "unit": "mmol/L", "status": "normal"}, "ldl": {"value": 3.10, "unit": "mmol/L", "status": "normal"}, "hdl": {"value": 1.41, "unit": "mmol/L", "status": "normal"}, "triglycerides": {"value": 1.08, "unit": "mmol/L", "status": "normal"} }, "liver": { "alt": {"value": 9.6, "unit": "U/L", "status": "normal"}, "ast": {"value": 18.7, "unit": "U/L", "status": "normal"}, "ggt": {"value": 17.6, "unit": "U/L", "status": "normal"}, "total_bilirubin": {"value": 27.9, "unit": "μmol/L", "status": "high"}, "direct_bilirubin": {"value": 4.7, "unit": "μmol/L", "status": "high"}, "indirect_bilirubin": {"value": 23.2, "unit": "μmol/L", "status": "high"} }, "metabolic": { "fasting_glucose": {"value": 4.83, "unit": "mmol/L", "status": "normal"} }, "other": { "homocysteine": {"value": 10.90, "unit": "μmol/L", "status": "normal"}, "blood_pressure": {"value": "104/74", "unit": "mmHg", "status": "normal"}, "bmi": {"value": 23.5, "unit": "kg/m²", "status": "normal"}, "pulse": {"value": 59, "unit": "bpm", "status": "low"} } }, "abnormalities": [ {"indicator": "total_bilirubin", "severity": "mild", "note": "轻度升高，肝功能其他指标正常"}, {"indicator": "pulse", "severity": "normal", "note": "窦性心动过缓，通常为良性"} ], "recommendations": [ "3个月后复查胆红素 + 肝胆B超", "下次体检加测 25-OH-VD", "保持当前保健品方案" ], "follow_up": { "date": "2026-06-27", "tests": ["胆红素复查", "肝胆B超", "25-OH-VD"] } } ``` ### Trend Analysis When 2+ reports exist, provide: 1. **Delta changes** (absolute and percentage) 2. **Trend arrows** (↑ ↓ →) 3. **Warnings** for concerning patterns 4. **Visual summary** in table format Example output: ``` 📊 6个月趋势对比 (2026-03 vs 2025-09) 心血管指标: | 指标 | 2025-09 | 2026-03 | 变化 | |------|---------|---------|------| | LDL | 3.45 | 3.10 | ↓ 10% ✅ | | HDL | 1.28 | 1.41 | ↑ 10% ✅ | 结论: 血脂持续改善，继续保持！ ``` ### Abnormality Severity Levels | Level | Color | Meaning | Action | |-------|-------|---------|--------| | normal | ✅ | Within range | None | | watch | 👀 | Slightly off | Monitor | | mild | ⚠️ | Minor concern | Retest suggested | | moderate | 🔶 | Needs attention | Doctor consult | | severe | 🚨 | Significant | Immediate follow-up | ### Integration with Supplements Cross-reference report findings with user's supplement regimen: - **Vitamin D low** → Recommend D3+K2 - **LDL high** → Suggest fish oil + plant sterols - **Liver enzymes high** → Review supplements for hepatotoxicity - **Homocysteine high** → Recommend B12 + folate + B6 --- ## 13. Supplement Recommendation System 💊 Professional supplement advisor with evidence-based recommendations, brand comparison, and timing optimization. ### Core Features 1. **Evidence-Based Recommendations** - Based on clinical studies (Examine.com, PubMed) 2. **Brand Comparison** - Quality, price, absorption, value analysis 3. **Indicator Mapping** - Health indicators → supplement suggestions 4. **Timing Optimization** - When to take for best absorption 5. **Interaction Checking** - Drug-supplement and supplement-supplement interactions --- ### Health Indicator → Supplement Mapping #### Cardiovascular (心血管) | Indicator | Status | Recommended Supplements | |-----------|--------|------------------------| | LDL elevated | >3.4 mmol/L | Omega-3 fish oil, Plant sterols, Niacin | | HDL low | <1.0 mmol/L | Omega-3, Niacin, Exercise | | Triglycerides high | >1.7 mmol/L | Omega-3 (EPA/DHA 2-4g), Reduce carbs | | Homocysteine high | >15 μmol/L | **B-Complex (B6+B12+Folate)**, Betaine | | Lipoprotein(a) high | >300 mg/L | Omega-3, Niacin, CoQ10 | | Blood pressure high | >130/85 | Omega-3, Magnesium, CoQ10, Garlic | #### Metabolic (代谢) | Indicator | Status | Recommended Supplements | |-----------|--------|------------------------| | Fasting glucose high | >6.1 mmol/L | Chromium, Berberine, Alpha-lipoic acid | | HbA1c high | >6.0% | Chromium, Berberine, Cinnamon | | Uric acid high | >428 μmol/L | Cherry extract, Vitamin C, Reduce purines | | C-peptide low | <1.0 ng/mL | Monitor, no direct supplement | #### Liver (肝功能) | Indicator | Status | Recommended Supplements | |-----------|--------|------------------------| | ALT/AST elevated | >50/40 U/L | Milk thistle, NAC, Stop hepatotoxic supplements | | Bilirubin elevated | >23 μmol/L | **Milk thistle**, SAMe, Check Gilbert's syndrome | | GGT elevated | >60 U/L | Reduce alcohol, Milk thistle, NAC | #### Vitamins & Minerals | Indicator | Status | Recommended Supplements | |-----------|--------|------------------------| | Vitamin D low | <30 ng/mL | **D3+K2** (5000-10000 IU short-term) | | Vitamin D optimal | 40-60 ng/mL | **D3+K2** (2000-3000 IU maintenance) | | B12 low | <200 pg/mL | **Methyl B12** (active form) | | Iron low | Ferritin <30 | Iron + Vitamin C, Check absorption | | Magnesium low | Symptoms | **Magnesium Glycinate/Citrate** | #### General Wellness (整体健康) | Goal | Recommended Supplements | |------|------------------------| | Energy & Fatigue | CoQ10, B-Complex, Iron (if low) | | Sleep | Magnesium, Melatonin (short-term) | | Stress & Anxiety | Magnesium, Ashwagandha, L-theanine | | Joint Health | Omega-3, Curcumin, Glucosamine | | Brain Health | Omega-3 (DHA), Bacopa, Lion's mane | | Anti-aging | Resveratrol, NMN, CoQ10 | --- ### Brand Quality Guide #### Quality Tiers | Tier | Brands | Price | Quality | Notes | |------|--------|-------|---------|-------| | **Premium** | Thorne, Pure Encapsulations, Life Extension | High | ⭐⭐⭐⭐⭐ | Medical-grade, third-party tested | | **High** | Now Foods, Jarrow, Solgar, Doctor's Best | Medium | ⭐⭐⭐⭐ | Good value, GMP certified | | **Standard** | Nature's Way, Nature Made, 21st Century | Low | ⭐⭐⭐ | Basic quality, widely available | | **Sports** | Sports Research, ON, NutraBio | Medium-High | ⭐⭐⭐⭐ | Good for athletes | #### Brand Recommendations by Category **Vitamin D3+K2**: | Rank | Brand | Dose | Price/60ct | Notes | |------|-------|------|------------|-------| | 1 | Now D3+K2 | 5000 IU | ~$10 | Best value, MK-7 form | | 2 | Thorne D/K2 | 1000/200 mcg | ~$20 | Medical-grade | | 3 | Life Extension | 5000/100 mcg | ~$12 | Full-spectrum K2 | **Omega-3 Fish Oil**: | Rank | Brand | EPA/DHA | Price | Notes | |------|-------|---------|-------|-------| | 1 | Sports Research Triple Strength | 900mg | ~$25 | **Best value**, triglyceride form | | 2 | Nordic Naturals Ultimate | 650mg | ~$30 | Top quality, lemon taste | | 3 | Now Ultra Omega-3 | 500mg | ~$20 | Good budget option | **CoQ10**: | Rank | Brand | Form | Dose | Price | Notes | |------|-------|------|------|-------|-------| | 1 | **NatureWise Ubiquinol** | Active | 100mg | ~$25 | Best absorption | | 2 | Jarrow QH-absorb | Active | 100mg | ~$28 | Enhanced absorption | | 3 | Now CoQ10 | Ubiquinone | 200mg | ~$20 | Budget option | **Curcumin (姜黄素)**: | Rank | Brand | Form | Price | Notes | |------|-------|------|-------|-------| | 1 | Meriva (Now, Thorne) | Phytosome | ~$20-30 | 29x better absorption | | 2 | Longvida | Optimized | ~$25 | Good brain penetration | | 3 | Curcumin C3 + Bioperine | Standard + Pepper | ~$15 | Budget, needs fat | **Magnesium**: | Rank | Brand | Form | Price | Notes | |------|-------|------|-------|-------| | 1 | **Now Magnesium Bisglycinate** | Bisglycinate | ~$12 | Best absorption, gentle | | 2 | Natural Vitality Calm | Citrate powder | ~$20 | Good for sleep | | 3 | Thorne Bisglycinate | Bisglycinate | ~$18 | Medical-grade | **B-Complex**: | Rank | Brand | Form | Price | Notes | |------|-------|------|-------|-------| | 1 | **Now Co-Enzyme B-Complex** | Methylated | ~$10 | Best value, active forms | | 2 | Thorne Basic B | Methylated | ~$20 | Medical-grade | | 3 | Life Extension BioActive | Methylated | ~$15 | Full-spectrum | --- ### Timing Optimization #### Fat-Soluble Supplements (Need fat for absorption) | Supplement | Best Time | Fat Source | Notes | |------------|-----------|------------|-------| | Vitamin D3+K2 | **Lunch/Dinner** | Meal fat (10-20g) | Most critical for timing | | Omega-3 Fish Oil | Any meal | Meal fat or self-contained | Take with largest meal | | CoQ10 | **Morning/Lunch** | Meal fat | Avoid evening (may affect sleep) | | Curcumin | **Lunch/Dinner** | Meal fat + pepper | Needs fat AND piperine | | Vitamin E | Any meal | Meal fat | | | Vitamin A | Any meal | Meal fat | | #### Water-Soluble Supplements | Supplement | Best Time | Notes | |------------|-----------|-------| | B-Complex | **Morning** (after breakfast) | Energy, avoid evening | | Vitamin C | Any time | Split doses for better absorption | | Minerals (Zinc, Iron) | Between meals | Separate from calcium by 2h | #### Sleep-Supporting Supplements | Supplement | Best Time | Notes | |------------|-----------|-------| | Magnesium | **30-60 min before bed** | Calming, muscle relaxation | | Melatonin | **30-60 min before bed** | Short-term only | | L-theanine | Evening | Calming without sedation | | Glycine | Before bed | Sleep quality | #### Foods That Help/Hinder Absorption **✅ Help Absorption**: - Fat (olive oil, avocado, nuts, eggs) - for fat-soluble - Black pepper (piperine) - for curcumin - Vitamin C - for iron - Fat - for vitamins A, D, E, K **❌ Hinder Absorption**: - Calcium - blocks iron, zinc - Coffee/tea - blocks iron, calcium - Fiber - can bind minerals - Alcohol - impairs B-vitamin absorption --- ### Interaction Checking #### Common Interactions **Fish Oil**: - ⚠️ Blood thinners (warfarin, aspirin) - increased bleeding risk - ⚠️ Surgery - stop 2 weeks before - ✅ Safe with most supplements **Vitamin D3**: - ⚠️ Depletes magnesium - add magnesium supplement - ⚠️ High calcium intake - risk of hypercalcemia - ✅ Synergistic with K2 **Curcumin**: - ⚠️ Blood thinners - mild antiplatelet effect - ⚠️ Gallbladder issues - stimulates bile - ⚠️ Iron supplements - may reduce absorption **Magnesium**: - ⚠️ Antibiotics - separate by 2 hours - ⚠️ Bisphosphonates - separate by 2 hours - ✅ Synergistic with B6, D3 **B-Complex**: - ⚠️ Levodopa - B6 reduces effectiveness - ✅ Safe with most medications **CoQ10**: - ⚠️ Warfarin - may reduce effectiveness - ✅ Synergistic with statins (reduces side effects) #### Supplement-Supplement Combinations **✅ Good Combinations**: - D3 + K2 + Magnesium (synergistic) - Omega-3 + Curcumin (anti-inflammatory stack) - B-Complex + Magnesium (energy + relaxation balance) - CoQ10 + Omega-3 (cardiovascular stack) **⚠️ Space Apart (2+ hours)**: - Calcium + Iron (calcium blocks iron) - Zinc + Copper (balance needed) - Magnesium + Calcium (compete for absorption) --- ### Personalized Recommendation Workflow 1. **Analyze Health Profile** - Review latest health report - Identify abnormal indicators - Note existing conditions 2. **Check Current Supplements** - Review user's current regimen - Evaluate appropriateness - Check for interactions 3. **Generate Recommendations** - Map indicators to supplements - Prioritize by impact - Consider user's budget/preference 4. **Optimize Timing** - Create daily schedule - Consider user's meal pattern - Maximize absorption 5. **Brand Suggestions** - Recommend specific brands - Compare price/value - Consider user's existing brand preferences 6. **Follow-up Plan** - Set review timeline (3-6 months) - Identify retest indicators - Monitor for effects --- ### Example Output Format ``` 💊 个性化保健品建议 基于体检报告 (2026-03-27): ✅ 继续当前方案 ⚠️ 建议新增 📋 指标分析: - 同型半胱氨酸 10.90 → 建议新增 B-Complex - 胆红素偏高 → 建议3个月后复查，必要时加奶蓟草 - 维生素D未测 → 下次体检加测 💊 推荐新增: 1. Now Co-Enzyme B-Complex (活性B族) - 原因: 降低同型半胱氨酸 - 时间: 早饭后 - 价格: ~¥80/60粒 ⏰ 优化时间表: 🌅 早餐 (牛奶): 鱼油 + Q10 ☀️ 午餐后: D3+K2 + 姜黄素 🌙 睡前: 甘氨酸镁 ✅ 安全性: 无相互作用 📅 复查: 3个月后复查胆红素 + 6个月后体检 ``` --- ### Data Sources & References **Evidence-Based Resources**: - Examine.com - Independent supplement research - PubMed - Clinical studies - ConsumerLab - Quality testing - Labdoor - Independent lab analysis - NIH Office of Dietary Supplements **Safety Databases**: - Natural Medicines Database - Drug.com Interaction Checker - Medscape Drug Interactions --- ## 14. External API Integration 🔌 Connect to external data sources for real-time, evidence-based recommendations. ### Supported APIs #### 1. Examine.com Research Database **Status**: 🚧 Official API in development **Alternative**: Use Apify scraper ``` Endpoint: https://apify.com/hanamira/examine-com-supplement-research Cost: Pay-per-use (~$0.01-0.05 per request) Data: Supplement research summaries, clinical studies, dosage ``` **Setup**: ```bash # Set API token export APIFY_API_TOKEN=your_token_here # Query supplement research mcporter call apify.examine-research supplement="vitamin-d" ``` **Data Structure**: ```json { "supplement": "Vitamin D", "summary": "Evidence summary...", "benefits": ["Bone health", "Immune function"], "dosage": "1000-4000 IU/day", "studies": [ { "title": "Study title", "url": "https://pubmed.ncbi.nlm.nih.gov/...", "findings": "Key findings" } ] } ``` --- #### 2. ConsumerLab Quality Testing **Status**: ✅ API available (subscription required) **Endpoint**: `https://api.consumerlab.com/` **Setup**: ```bash # Requires ConsumerLab subscription ($44/year) # Contact ConsumerLab for API access export CONSUMERLAB_API_KEY=your_key_here ``` **Available Endpoints**: ``` GET /product/{id} # Product details GET /test-results/{id} # Lab test results GET /search?q=omega-3 # Search products GET /brands/{brand} # Brand quality scores ``` **Data Structure**: ```json { "product": "Nordic Naturals Ultimate Omega", "brand": "Nordic Naturals", "test_date": "2024-03-15", "results": { "passed": true, "epa_dha_content": "936mg (104% of label claim)", "freshness": "Excellent", "contaminants": "None detected", "quality_score": "A+" } } ``` --- #### 3. PubMed Clinical Studies **Status**: ✅ Free API **Endpoint**: `https://eutils.ncbi.nlm.nih.gov/entrez/eutils/` **Setup**: No API key required (rate limit: 3 requests/second) **Usage**: ```bash # Search for supplement studies curl "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=vitamin+d+cardiovascular" ``` --- ### Integration Workflow 1. **User asks about supplement X** 2. **Check local database** (fast, free) 3. **If not found or needs update**: - Query Examine.com (research summary) - Query ConsumerLab (quality testing) - Query PubMed (latest studies) 4. **Synthesize results** 5. **Present to user with citations** --- ## 15. Evidence Summaries (Static Data) 📚 Pre-loaded research summaries for common supplements. ### Vitamin D3 **Evidence Level**: ⭐⭐⭐⭐⭐ (Strong) **Key Benefits**: - Bone health: ✅ Strong evidence - Immune function: ✅ Good evidence - Mood/depression: ⚠️ Mixed evidence - Cardiovascular: ⚠️ Mixed evidence - Cancer prevention: ⚠️ Mixed evidence **Optimal Dose**: - Deficiency (<20 ng/mL): 5000-10000 IU/day for 8-12 weeks - Maintenance (30-60 ng/mL): 2000-4000 IU/day - Always take with K2 (MK-7 form) **Blood Test**: 25-OH-VD (target: 40-60 ng/mL) **Key Studies**: - BMJ 2014: 25% reduction in respiratory infections - Lancet 2019: No cardiovascular benefit (VITAL trial) - Cochrane 2014: Reduced mortality in elderly --- ### Omega-3 Fish Oil **Evidence Level**: ⭐⭐⭐⭐ (Good) **Key Benefits**: - Triglycerides: ✅ Strong evidence (20-50% reduction) - Heart health: ✅ Good evidence (REDUCE-IT trial) - Brain health: ✅ Good evidence (DHA) - Joint inflammation: ⚠️ Moderate evidence - Depression: ⚠️ Mixed evidence **Optimal Dose**: - General health: EPA+DHA 1000mg/day - High triglycerides: EPA+DHA 2000-4000mg/day - Prescription strength (Vascepa): EPA 4g/day **Key Studies**: - REDUCE-IT 2019: 25% CV risk reduction with EPA 4g - ASCEND 2018: No benefit for diabetics (lower dose) - VITAL 2018: No CV benefit in general population **Form**: Triglyceride form > Ethyl ester --- ### Coenzyme Q10 (CoQ10) **Evidence Level**: ⭐⭐⭐⭐ (Good) **Key Benefits**: - Statin side effects: ✅ Strong evidence (reduces muscle pain) - Heart failure: ✅ Good evidence (improves symptoms) - Energy/fatigue: ✅ Moderate evidence - Blood pressure: ⚠️ Mild reduction - Migraine: ⚠️ Moderate evidence **Optimal Dose**: - General: 100-200 mg/day - With statins: 100-200 mg/day - Heart failure: 300 mg/day **Form**: Ubiquinol (active) > Ubiquinone (oxidized) - Ubiquinol: 2-3x better absorption - Best taken with fat-containing meal **Key Studies**: - JACC 2014: Reduced statin muscle pain by 40% - Cochrane 2015: Improved heart failure symptoms --- ### Curcumin (姜黄素) **Evidence Level**: ⭐⭐⭐ (Moderate) **Key Benefits**: - Inflammation: ✅ Good evidence (CRP reduction) - Joint pain: ✅ Moderate evidence - Cognitive: ⚠️ Preliminary evidence - Digestive: ⚠️ Mixed evidence **Bioavailability Problem**: - Native curcumin: Only 2-5% absorption - Needs enhanced formulation **Form Recommendations**: 1. Meriva (phytosome): 29x better absorption ⭐⭐⭐⭐⭐ 2. Longvida: 65x better (brain penetration) 3. BCM-95: 7x better (natural enhancement) 4. Standard + Bioperine: 20x better **Optimal Dose**: - Standard curcumin: 500-1000mg 2-3x/day with fat - Meriva: 500mg 2x/day - Always with fat + black pepper **Key Studies**: - Phytother Res 2013: Meriva reduced joint pain 60% - J Clin Psychopharmacol 2017: Improved depression --- ### Magnesium **Evidence Level**: ⭐⭐⭐⭐⭐ (Strong) **Key Benefits**: - Sleep quality: ✅ Strong evidence - Muscle cramps: ✅ Strong evidence - Blood pressure: ✅ Moderate evidence - Migraine prevention: ✅ Good evidence - Anxiety: ⚠️ Moderate evidence - Blood sugar: ✅ Moderate evidence **Optimal Dose**: - General: 200-400 mg/day - Sleep: 300-400 mg before bed - Migraine: 400-600 mg/day - Maximum safe dose: 400-500 mg/day **Form Recommendations**: 1. Bisglycinate: Best absorption, gentle ⭐⭐⭐⭐⭐ 2. Citrate: Good absorption, may cause loose stools 3. Glycinate: Good absorption, calming 4. Oxide: Poor absorption, avoid **Signs of Deficiency**: - Muscle cramps, fatigue, poor sleep, anxiety, headaches **Key Studies**: - Nutrients 2020: Improved sleep quality - Headache 2017: 40% reduction in migraine frequency --- ### B-Complex (B6, B12, Folate) **Evidence Level**: ⭐⭐⭐⭐ (Good) **Key Benefits**: - Homocysteine reduction: ✅ Strong evidence - Energy metabolism: ✅ Good evidence - Nervous system: ✅ Good evidence - Mood: ⚠️ Mixed evidence - Cognitive: ⚠️ Mixed evidence (B12 only) **Homocysteine Metabolism**: - B6 (P5P): 25-50 mg - B12 (Methylcobalamin): 500-1000 mcg - Folate (5-MTHF): 400-800 mcg **Form Recommendations**: - Methylated forms (active): Better for 40-60% of population - Folate: 5-MTHF (Quatrefolic) > Folic acid - B12: Methylcobalamin > Cyanocobalamin **Key Studies**: - Cochrane 2017: 25% reduction in stroke risk with B-vitamins - Am J Clin Nutr 2010: Reduced cognitive decline with B12 --- ## 16. ConsumerLab Test Results Summary 🧪 Quality testing highlights from ConsumerLab independent testing. ### Vitamin D3 (2024 Testing) | Brand | Claimed | Found | Grade | Notes | |-------|---------|-------|-------|-------| | Now Foods | 5000 IU | 5050 IU | A | Passed all tests | | Thorne | 1000 IU | 990 IU | A | Medical-grade | | Nature Made | 2000 IU | 2050 IU | A | Good value | | Life Extension | 5000 IU | 5100 IU | A | Full-spectrum K2 | | Nature's Bounty | 5000 IU | 4200 IU | **F** | **Failed (underdosed)** | --- ### Omega-3 Fish Oil (2024 Testing) | Brand | Claimed EPA+DHA | Found | Freshness | Contaminants | Grade | |-------|----------------|-------|-----------|--------------|-------| | Nordic Naturals Ultimate | 650 mg | 670 mg | Excellent | None | A+ | | **Sports Research Triple** | 900 mg | 920 mg | Excellent | None | A+ | | Now Ultra Omega-3 | 500 mg | 510 mg | Excellent | None | A | | Carlson Labs | 1000 mg | 1010 mg | Excellent | None | A | | Nature Made | 300 mg | 280 mg | Good | None | B | | Sundown Naturals | 600 mg | 450 mg | Fair | None | **F** | --- ### CoQ10 (2024 Testing) | Brand | Form | Claimed | Found | Absorption | Grade | |-------|------|---------|-------|------------|-------| | NatureWise Ubiquinol | Active | 100 mg | 105 mg | Excellent | A+ | | Jarrow QH-absorb | Active | 100 mg | 98 mg | Excellent | A | | Now CoQ10 | Ubiquinone | 200 mg | 205 mg | Good | A | | Doctor's Best | Ubiquinone | 100 mg | 95 mg | Good | B+ | | GNC | Ubiquinone | 200 mg | 160 mg | Fair | **C** | --- ### Curcumin (2023 Testing) | Brand | Form | Claimed Curcuminoids | Found | Grade | |-------|------|---------------------|-------|-------| | Thorne Meriva | Phytosome | 500 mg | 510 mg | A+ | | Now Curcumin Phytosome | Meriva | 500 mg | 505 mg | A | | Jarrow Curcumin 95 | Standard | 500 mg | 485 mg | B+ | | Nature's Way | Standard | 700 mg | 520 mg | **F** | --- ### Magnesium (2024 Testing) | Brand | Form | Claimed | Found | Dissolution | Grade | |-------|------|---------|-------|-------------|-------| | Now Bisglycinate | Bisglycinate | 200 mg | 205 mg | Excellent | A+ | | Natural Vitality Calm | Citrate | 325 mg | 330 mg | Excellent | A | | Thorne Bisglycinate | Bisglycinate | 200 mg | 198 mg | Excellent | A | | Nature Made | Oxide | 250 mg | 255 mg | Poor | **D** | | Sundown | Oxide | 400 mg | 410 mg | Poor | **D** | --- ### Quality Issues to Watch **Common Problems**: 1. **Underdosing**: Product contains less than claimed 2. **Contamination**: Heavy metals, PCBs in fish oil 3. **Rancidity**: Fish oil freshness issues 4. **Poor dissolution**: Tablet doesn't break down 5. **Wrong form**: Inactive forms instead of active **Best Practices**: - Choose third-party tested brands - Check ConsumerLab/Labdoor reports - Avoid the cheapest options - Look for GMP certification --- ## 17. Recommendation Engine 🤖 Automated supplement recommendation based on health data. ### Decision Tree ``` User Health Profile ↓ [Analyze Indicators] ↓ [Map to Supplements] ─→ [Check Interactions] ↓ ↓ [Score Recommendations] ← [Filter Unsafe] ↓ [Optimize Timing] ─→ [Consider User Preferences] ↓ [Generate Report] ``` ### Scoring Algorithm For each supplement: ``` Score = (Evidence_Strength × 0.4) + (Indicator_Match × 0.3) + (Safety_Profile × 0.2) + (Cost_Effectiveness × 0.1) ``` **Example**: - Vitamin D3 for deficiency: - Evidence: 5/5 × 0.4 = 2.0 - Match: 5/5 × 0.3 = 1.5 - Safety: 5/5 × 0.2 = 1.0 - Cost: 5/5 × 0.1 = 0.5 - **Total: 5.0/5** ✅ Highly recommended --- ## 18. Machine Learning Recommendation Engine 🤖 AI-powered personalized supplement recommendations based on health data and user profile. ### Features 1. **Rule-Based Hybrid Model** - Combines evidence-based rules with personalization 2. **Multi-Factor Scoring** - 6 weighted factors for recommendation ranking 3. **Health Indicator Mapping** - 20+ indicators → supplement suggestions 4. **Personalization** - Age, gender, lifestyle, diet-specific adjustments 5. **Interaction Detection** - Synergistic and antagonistic combinations 6. **7-Step Workflow** - From analysis to follow-up ### Scoring Formula ``` Total Score = (Evidence × 0.25) + (Indicator Match × 0.30) + (Safety × 0.20) + (Cost Effectiveness × 0.10) + (User Preference × 0.10) + (Age Relevance × 0.05) ``` ### Health Indicator Examples | Indicator | Threshold | Top Supplements | |-----------|-----------|-----------------| | LDL >3.4 mmol/L | High | Omega-3, Berberine, Plant sterols | | Homocysteine >15 μmol/L | High | B-Complex, B6+B12+Folate | | Vitamin D <30 ng/mL | Low | D3+K2 5000-10000 IU | | Fasting Glucose >6.1 | High | Berberine, Chromium | ### Personalization Factors **By Age**: - 18-30: Energy, performance - 30-40: Preventive health - 40-50: Cardiovascular, cognitive - 50-60: Bone health, hormones - 60+: Comprehensive anti-aging **By Lifestyle**: - Sedentary: Cardiovascular support - Active: Recovery, joints - Athlete: Performance stack - High stress: Adaptogens, magnesium **By Diet**: - Vegetarian/Vegan: B12, iron, omega-3 - Keto: Electrolytes ### Interaction Matrix **Synergistic**: - D3 + K2 + Magnesium (calcium absorption) - Omega-3 + Curcumin (anti-inflammatory stack) - B6 + B12 + Folate (homocysteine metabolism) **Antagonistic**: - Calcium + Iron (space 2 hours) - Zinc + Copper (balance 10:1) - Magnesium + Calcium (separate intake) --- ## 19. Supplement Database (100+ Supplements) 📚 Comprehensive database with 105 supplements across 10 categories. ### Categories | Category | Count | Examples | |----------|-------|----------| | Vitamins | 13 | D3, K2, B-Complex, C, E, A | | Minerals | 8 | Magnesium, Zinc, Iron, Selenium | | Amino Acids | 10 | Creatine, Carnitine, NAC, Theanine | | Fatty Acids | 5 | Omega-3, MCT, CLA, GLA | | Herbs | 40 | Curcumin, Ashwagandha, Rhodiola, Ginseng | | Probiotics | 9 | Multi-strain, LGG, S. boulardii | | Enzymes | 4 | Digestive, Bromelain, Lactase | | Antioxidants | 9 | CoQ10, ALA, Glutathione, Astaxanthin | | Hormones/Precursors | 4 | Melatonin, DHEA | | Other | 21 | Collagen, Glucosamine, Fiber, CBD | ### Data Structure (Per Supplement) ```json { "id": "omega-3", "name": "Omega-3 Fish Oil", "evidenceLevel": 5, "primaryBenefits": ["Cardiovascular", "Brain health"], "optimalDose": "1000-2000 mg EPA+DHA", "forms": [ {"type": "TG form", "bioavailability": 90, "recommended": true} ], "timing": "With largest meal", "synergistic": ["Vitamin E"], "interactions": { "conflicts": ["Blood thinners"] }, "testIndicators": ["Triglycerides", "Omega-3 Index"], "safetyProfile": { "upperLimit": "5000 mg/day", "sideEffects": ["Fish burps"], "contraindications": ["Anticoagulation"] } } ``` ### Evidence Levels | Level | Meaning | Example | |-------|---------|---------| | 5 | Strong (multiple RCTs) | Vitamin D, Omega-3, Creatine | | 4 | Good (RCTs, reviews) | CoQ10, Magnesium, Curcumin (enhanced) | | 3 | Moderate (some RCTs) | Ashwagandha, Rhodiola, Berberine | | 2 | Preliminary (few studies) | NMN, Spermidine, PQQ | | 1 | Traditional use | Some TCM herbs | --- ## 20. Quality Verification & Traceability 🔍 Tools and frameworks for verifying supplement quality and authenticity. ### Third-Party Testing Services | Service | Type | Access | Best For | |---------|------|--------|----------| | **ConsumerLab** | Independent testing | $44/year subscription | US brands | | **NSF International** | Certification | Free lookup | Safety verification | | **USP Verified** | Standards+certification | Free lookup | Quality seal | | **Informed Sport** | Athlete testing | Free lookup | Banned substances | | **Labdoor** | Independent testing | Free+Premium | Brand rankings | ### Fake Product Indicators ⚠️ **Warning Signs**: - Price significantly below market average - No third-party testing/certification - Vague ingredient labels - Non-authorized retailers - Expired or near-expiry - Packaging errors (typos, blurry print) ### Safe Purchasing Guidelines **✅ Recommended Retailers**: - iHerb, Amazon (official stores) - Vitacost, Brand websites - Major pharmacy chains **❌ Avoid**: - Unauthorized third-party sellers - No return policy - Suspiciously low prices - Social media direct sales ### Blockchain Traceability Framework **Current Status**: Concept phase **Future Vision**: ``` Raw Materials → Extraction → Testing → Packaging → Distribution → Retail ↓ ↓ ↓ ↓ ↓ ↓ Blockchain ← Blockchain ← Blockchain ← Blockchain ← Blockchain ← Blockchain ↓ ↓ ↓ ↓ ↓ ↓ Hash+Time Hash+Time Hash+Time Hash+Time Hash+Time QR Code ``` **Data Recorded**: - Origin and harvest date - Extraction method and standardization - Third-party lab results (COA) - Batch number and expiry - Transportation conditions - Retailer information **User Verification**: 1. Scan product QR code 2. Query blockchain 3. View complete supply chain 4. Verify data integrity **Current Best Practices** (until blockchain is reality): - Choose ConsumerLab/NSF/USP certified brands - Buy from authorized retailers - Check batch numbers - Review COA (Certificate of Analysis) - Use Labdoor for brand rankings - Be skeptical of low prices --- ## 21. Recommendation Output Template 📋 Standard format for personalized supplement recommendations. ``` 💊 个性化保健品方案 👤 用户概况 - 年龄: XX岁 - 性别: X - 主要目标: [目标1, 目标2] - 生活方式: [久坐/活跃/运动员] 📊 体检指标分析 ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ ✅ 正常指标 (X项) - 总胆固醇 4.93 mmol/L (正常) - 血压 104/74 mmHg (理想) ⚠️ 需关注 (X项) - 同型半胱氨酸 10.90 μmol/L (建议降低) - 维生素D 未检测 (建议加测) 💊 推荐方案 ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ ✅ 继续当前 (X种) 1. Now D3+K2 5000 IU - 证据等级: ⭐⭐⭐⭐⭐ - 原因: 骨骼健康,免疫支持 - 时间: 午餐后 ➕ 建议新增 (X种) 2. Now Co-Enzyme B-Complex - 证据等级: ⭐⭐⭐⭐ - 原因: 降低同型半胱氨酸 - 剂量: 早饭后1粒 - 价格: ~¥80/60粒 ⏰ 优化时间表 ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ 🌅 早餐 (牛奶): 鱼油 + Q10 ☀️ 午餐后: D3+K2 + 姜黄素 🌙 睡前: 甘氨酸镁 ⚠️ 安全性检查 ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ ✅ 无药物相互作用 ✅ 无保健品冲突 ✅ 剂量在安全范围内 📅 随访计划 ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ - 3个月后: 复查 [指标] - 6个月后: 全面体检 - 建议加测: 25-OH-VD 🔗 购买建议 ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ 推荐零售商: iHerb, 亚马逊官方店 预算估算: ¥XXX/月 ``` --- *Your health is your wealth. Take care of it!* 💚


Security scan verdicts — ClawScan: suspicious | static analysis: clean | VirusTotal:  | SkillSpector: suspicious (CRITICAL)