全米市長による気候行動指針 (Mayors National Climate Action Agenda) は、米国の市長による温室効果ガス排出削減を目的とした連合体である。 ロサンゼルス市長のEric Garcetti、元ヒューストン市長のAnnise Parker、元フィラデルフィア市長のMichael Nutterにより設立された。全米の279都市、人口にして18%以上をカバーしている。

2014年に創立されたこの組織は、2015年のパリ協定締結に先立ち、市長組織による市の組織化を支援するために、クリントン財団からスタートアップ資金100万ドルを得た。

この組織は、合意が撤回されたとしても、気候変動に関するパリ協定の排出目標を維持するというコミットメントを表明している。

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