酒井清孝

酒井 清孝（さかい きよたか、1941年6月26日 - ）は、日本の理工学者。

現在は早稲田大学名誉教授、公益財団法人松籟科学技術振興財団理事、医療法人社団善仁会Gr顧問、人工臓器歴史遺産研究会代表である。

化学工学を中心とした医療工学の研究を行い、人工臓器の開発や設計に携わった。生命維持管理装置の操作・設計に化学工学の知識を生かして、現代の高度先進医療を支える医療工学の発展を促進した研究者である。生命維持管理装置を扱う臨床工学技士、医学に関わる理工学研究者、人工臓器を扱う医師とともに研究を行い、多くの業績を残している。
秋山敏、林寛、穂坂英明、横山真喜男、峰島三千男、安住利恵子、小沢治子、鶴岡秀志、竹澤真吾、松田兼一、山下明泰、小澤喜久夫、金森敏幸、金武潤、吉田亮、櫛谷文彦、阪上正裕、柳沢真澄、吉見靖男、桜井公美、小久保謙一、福田誠、氷見直之、宮坂武寛、薬師寺大二、青柳里果、松田範昭、小林純、荏原充宏、熊代善一、長瀬健一、葉山順代、山本健一郎、井戸田直和、小川武人、岩永進太郎、長谷川麗、小松寛、阪田宏樹、滑川亘希、井上幹康などの理工学研究者、企業経営者、企業技術者、医学研究者、医師を育てた。

 経歴 
東京都出身
1965年 早稲田大学理工学部応用化学科卒
1967年 同大学院理工学研究科応用化学専攻修士課程修了（工学修士）
1970年 同大学院理工学研究科応用化学専攻博士課程修了 (工学博士)（城塚正教授指導）
1970年 静岡大学工学部化学工学科専任講師（文部教官教育職）
1972年 同助教授（文部教官教育職）
1973年 早稲田大学理工学部応用化学科助教授
1978年 同教授
2007年 早稲田大学先進理工学部応用化学科教授
2012年 早稲田大学名誉教授
クリーブランドクリニック人工臓器研究所客員教授、テキサス大学客員研究員、静岡大学・大阪市立大学・芝浦工業大学・東京農工大学・横浜国立大学・東京大学・東北大学・名古屋大学・東京女子医科大学・千葉大学・東京電機大学の非常勤講師を歴任

 役職 
日本膜学会第16年会組織委員長
第34回日本人工臓器学会大会長
日本医工学治療学会第13回学術大会大会長
日本人工臓器学会名誉会長
日本医工学治療学会名誉会員
日本膜学会名誉会員
化学工学会名誉会員
早稲田応用化学会名誉会員
日本急性血液浄化学会功労会員
化学工学会バイオ部会顧問
日本臨床工学技士会元顧問
医療法人社団善仁会顧問
公益財団法人松籟科学技術振興財団理事
一般社団法人透析技能検定試験制度協議会元副会長
日本エアデールテリア協会元理事長、元審査員
Honorary Editorial Board Member: Journal of Artificial Organs
AIChE (American Institute of Chemical Engineers) Senior Member
ASAIO (American Society for Artificial Organs) Member
EDTA (European Dialysis and Transplantation Association) Senior Member
NAMS (North American Membrane Society) Senior Member

 受賞・受章歴 
1965年 早稲田応用化学会小林賞
1981年 化学工学会関東支部功労賞
1992年 化学工学会研究賞
1994年 日本医科器械学会著述賞
1995年、1997年、1998年、2001年、2006年、2009年、2010年 日本人工臓器学会論文賞
1998年 化学工学会学会賞
1998年 化学工学会池田亀三郎記念賞
2011年 公益財団法人日本腎臓財団功労賞
2018年 日本生体医工学会論文賞・阪本賞
2021年 春の叙勲・瑞宝中綬章

 代表論文 

Fukuda M, Furuya T, Sadano K, et al: Electron microscopic confirmation of anisotropic pore characteristics for ECMO membranes theoretically validating the risk of SARS-CoV-2 permeation. Membranes, July 2021
Fukuda M, Tokumine A, Noda K, et al: Newly developed pediatric membrane oxygenator that suppresses excessive pressure drop in cardiopulmonary bypass and extracorporeal membrane oxygenation (ECMO). Membranes, 10, 362, 2020; doi:10.3390/membranes10110362
Fukuda M, Yoshimoto H, Saomoto H, et al: Validity of three-dimensional tortuous pore structure and fouling of hemoconcentration capillary membrane using the tortuous pore diffusion model and scanning probe microscopy. Membranes, 10, 315, 2020; doi:10.3390/membranes10110315
Fukuda M, Saomoto H, Mori T, et al: Impact of three-dimensional tortuous pore structure on polyethersulfone membrane morphology and mass transfer properties from a manufacturing perspective. J Artif Organs, 23, 171-179, 2019, https://doi.org/10.1007/s10047-019-01144-0
Komatsu H, Sakai K, Baba T, et al: Aggregation behavior of short-chained archaeal phospholipid analogs: Contribution of methyl branches to lipid hydrophobicity and membrane formability. Colloid and Interface Science Communications, 32, 100200, 2019
Fukuda M, Saomoto H, Shimizu T, et al: Obsevation and proposed measurement of three-dimensional tortuous capillary pores with depth for hollow fiber hemoconcentrator membrane using dynamic force microscopy. Adv Biomed Eng 8, 145-152, 2019
Fukuda M, Yoshimura K, Namekawa K, et al: Technical characterization of dialysis fluid flow and mass transfer rate in dialyzers with various filtration coefficients using dimensionless correlation equation. J Artif Organs, 20, 145-151, 2017
Fukuda M, Namekawa K, Sakai K: Identical dependence of dialysate-side mass transfer coefficient on Reynolds number using dimensionless correlation based on the mass transfer model in newly developed dialyzers and a downsized dialyzer. Adv Biomed Eng 5, 118-123, 2016
Fukuda M, Yamamoto K, Maeda K, Sakai K: Dependence of roller pump rotation on blood backflow and simple estimation of negative pressure required for blood withdrawal using backflow volume measurement at the arterial side-chamber inlet. Therapeutics and Engineering, 27, 21-28, 2015
Yamazaki K, Yakushiji T,  Sakai K: Nanoscale analysis of hydrophilicity-hydrophobicity distribution on inner surfaces of wet dialysis membranes by atomic force microscopy. J Membr Sci 396, 38-42, 2012
Akimoto J Nakayama M, Sakai K, et al: Synthesis of terminal-functionalized thermoresponsive diblock copolymers using biogradable macro-RAFT agents.　Polymer J 45, 233-237, 2012
Namekawa K, Matsuda M, Fukuda M, et al: Poly(N-vinyl-2-pyrrolidone) elution from polysulfone dialysis membrane by varying solvent and wall shear stress. J Artif Organs 15, 185-192, 2012
Hirano A, Kida S, Yamamoto K, et al: Experimental evaluation of flow and dialysis performance of hollow-fiber dialyzers with different packing densities. J Artif Organs 15, 168-175, 2012
Sakai K, Matsuda M: Solute removal efficiency and biocompatibility of the high-performance membrane - from engineering points of view. pp.11-22, in High-Performance Membrane Dialyzers ed by Saito A, Kawanishi H, Yamashita AC, et al, Contributions to Nephrology, Vol.173, 2011
Matsuda M, Yakushiji T, Sakai K: Effect of γ irradiation on the surface properties of wet polysulfone films containing poly(vinylpyrrolidone). Surf Interface Anal 43, 976-983, 2011
Idota N, Kikuchi A, Kobayashi J, et al: Modulation of graft architectures for enhancing hydrophobic interaction of biomolecules with thermoresponsive polymer-grafted surfaces. Colloids and Surfaces B: Biointerfaces 99, 95-101, 2011
Namekawa K, Kaneko A, Sakai K, et al: Longer storage of dialyzers increases elution of poly(N-vinyl-2-pyrrolidone) from polysulfone-group dialysis membranes. J Artif Organs 14, 52-57, 2011
Yamazaki K, Matsuda M, Yamamoto K, et al: Internal and surface structure characterization of cellulose triacetate hollow-fiber dialysis membranes. J Membr Sci 368, 34-40, 2011
Koga S, Yakushiji T, Matsuda M, et al: Functional-group analysis of polyvinylpyrrolidone on the inner surface of hollow-fiber dialysis membranes, by near-field infrared microspectroscopy. J Membr Sci 355, 208-213, 2010
Hirano A, Yamamoto K, Matsuda M, et al: Evaluation of dialyzer jacket structure and hollow-fiber dialysis membranes to achieve high dialysis performance. Ther Apher Dial 15, 66-74, 2010
Aoyagi S, Namekawa K, Yamamoto K, et al: Investigation of molecular surfaces with time-of-light secondary ion mass spectrometry. Surf Interface Anal 42, 1593-1597, 2010
Akimoto J, Nakayama M, Sakai K, et al: Thermally controlled intracellular uptake system of polymeric micelles possessing poly(N-isopropylamide)-based outer coronas. Mol Pharm 7, 926-935, 2010
Yamamoto K, Ogawa T, Matsuda M, et al: Membrane potential and charge density of hollow-fiber dialysis membrane. J Membr Sci 355, 182-185, 2010
Ogawa T, Koga S, Yakushiji T, et al: Development of device for chemiluminescence determination of superoxide generated inside a dialysis hollow-fiber membrane. J Artif Organs 13, 58-62, 2010
Namekawa K, Fukuda M, Matsuda M, et al: Nanotechnological characterization of human albumin adsorption on wet synthetic polymer dialysis membrane surfaces. ASAIO J 55, 236-242, 2009
Yoshimi Y, Narimatsu A, Nakayama K, et al: Development of an enzyme-free glucose sensor using the gate effect of a molecularly imprinted polymer. J Artif Organs 12, 264-270, 2009
Ogawa T, Aoyagi S, Miyasaka T, et al: Fluorescence enhancement of fluorescent isothiocyanate-labeled protein A caused by affinity binding with immunoglobulin G in bovine plasma. Sensors 9, 8271-8277, 2009
Akimoto J, Nakayama M, Sakai K, et al: Temperature-induced intracellular uptake of thermoresponsive polymeric micelles. Biomacromolecules 10, 1331-1336, 2009
Yamamoto K, Matsuda M, Hirano A, et al: Computational evaluation of dialysis fluid flow in dialyzers with variously designed jackets. Artif Organs 33, 481-486, 2009
Hirano A, Yamamoto K, Matsuda M, et al: Flow uniformity in oxygenators with different outlet port design. ASAIOJ 55, 209-212, 2009
Kunikata S, Fukuda M, Yamamoto K, et al: Technical characterization of dialysis fluid flow of newly developed dialyzers using mass transfer correlation equation. ASAIO J 55, 231-235, 2009
Sugiura S, Imano W, Takagi T et al: Thermoresponsive protein adsorption of poly(N-isopropylacrylamide)-modified streptavidin on polydimethylsiloxane microchannel surfaces. Biosens Bioelectron 24, 1135-1140, 2009
Matsuda M, Yamamoto K, Yakushiji T, et al: Nanotechnological evaluation of protein adsorption on dialysis membrane surface hydrophilized with polyvinylpyrrolidone. J Membr Sci 310, 219-228, 2008
Ebara M, Yamato M, Aoyagi T, et al: A novel approach to observing synergy effects of PHSRN on integrin-RGD binding using intelligent surfaces. Adv Mater 20, 3034-3038, 2008
Ebara M, Yamato M, Aoyagi T, et al: The effect of extensible PEG tethers on shielding between grafted thermo-responsive polymer chains and integrin-RGD binding. Biomaterials 29, 3650-3655, 2008
Akimoto J, Nakayama M, Sakai K, et al: Molecular design of outermost surface functionalized thermo-responsive polymeric micelles with biodegradable cores. J Polym Sci 46, 7127-7137, 2008
Matsuda M, Sato M, Sakata H, et al: Effects of fluid flow on elution of hydrophilic modifier from dialysis membrane surfaces. J Artif Organs 11, 148-155, 2008
Yamamoto K, Hayama M, Matsuda T, et al: Evaluation of asymmetrical structure dialysis membrane by tortuous capillary pore diffusion model. J Membr Sci 287, 88-93, 2007
Ogawa T, Shimazaki H, Aoyagi S, et al: Electrical oscillation at a water/octanol interface in a hydrophobic container. J Colloid Interface Sci 305, 195-197, 2007
Yamamoto K, Matsukawa H, Yakushiji T, et al: Technical evaluation of dialysate flow in a newly designed dialyzer. ASAIO J, 53, 36-40, 2007
Yamamoto K, Matsuda M, Okuoka M, et al: Antioxidation property of vitamin E-coated polysulfone dialysis membrane and recovery of oxidized vitamin E by vitamin C treatment. J Membr Sci 302, 115-118, 2007
Nakayama M, Chung JE, Miyazaki T, et al: Thermal modulation of intracellular drug distribution using thermoresponsive polymeric micelles. React Funct Polym 67, 1398-1407, 2007
Sekine S, Watanabe Y, Yoshimi Y, et al: Influence of solvents on chiral discriminative gate effect of moleculary imprinted poly(ethylene glycol dimethacrylate-co-methacrylic acid). Sens Actuators B 127, 512-517, 2007
Yamamoto K, Matsuda M, Hayama M, et al: Evaluation of the activity of endotoxin trapped by a hollow-fiber dialysis membrane. J Membr Sci 272, 211-216, 2006
Idota N, Kikuchi A, Kobayashi J, et al: Thermal modulated interaction of aqueous steroids using polymer-grafted capillaries. Langmuir 22, 425-430, 2006
Miyasaka T, Endo K, Mochizuki S, et al: Superoxide sensors. Sens Lett 4, 144-154, 2006
Nakamura M, Okano T, Miyazaki T, et al: Molecular design of biodegradable polymeric micelles for temperature-responsive drug release. J Control Release 115, 46-56, 2006
Ogawa T, Shimazaki H, Aoyagi S, et al: Novel modeling of electrical potential oscillation across a water/octanol/water liquid membrane. J Membr Sci 285, 120-125, 2006
Nagase K, Hasegawa U, Kohori F, et al: The photoresponse of a molybdenum porphyrin makes an artificial gill feasible. J Membr Sci 249, 235-243, 2005
Iwanaga S, Akiyama S, Kikuchi A, et al: Fabrication of a cell array on ultrathin hydrophilic polymer gels utilizing electron beam irradiation and UV excimer laser ablation. Biomaterials 26, 5395-5404, 2005
Nagase K, Kohori F, Sakai K, et al: Rearrangement of hollow fibers for enhancing oxygen transfer in an artificial gill using oxygen carrier solution. J Membr Sci 254, 207-217, 2005
Nagase K, Kohori F, Sakai K: Oxygen transfer performance of a membrane oxygenator composed of crossed and parallel hollow fibers. Biochem Eng J 24, 105-113, 2005
Yamamoto K, Hiwatari M, Kohori F, et al: Membrane fouling and dialysate flow pattern in an internal filtration-enhancing dialyzer. J Artif Organs 8, 198-205, 2005
Idota N, Kikuchi A, Kobayashi J, et al: Microfluidic valves comprising nanolayered thermoresponsive polymer-grafted capillaries. Adv Mater 17, 2723-2727, 2005
Yamamoto K, Kobayashi K, Endo K, et al: Hollow-fiber blood-dialysis membranes: superoxide generation, permeation and dismutation measured by chemiluminescence. J Artif Organs 8, 257-262, 2005
Hayama M, Yamamoto K, Kohori F, et al: How polysulfone dialysis membranes containing polyvinylpyrrolidone achieve excellent biocompatibility?. J Membr Sci 234, 41-49, 2004
Ebara M, Yamato M, Aoyagi T, et al: Temperature-responsive cell culture surfaces enable “on-off” affinity control between cell integrins and RGDS ligands. Biomacromolecules 5, 505-510, 2004
Hayama M, Yamamoto K, Kohori F, et al: Nanoscopic behavior of polyvinylpyrrolidone particles on polysulfone/polyvinylpyrrolidone film. Biomaterials 25, 1019-1028, 2004
Hattori K, Yoshimi Y, Ito T, et al: Effect of electrostatic interactions on gate effect in molecularly imprinted polymers. Electrochemistry 72, 508-510, 2004
Hattori K, Hiwatari M, Iiyama C, et al: Gate effect of theophylline-imprinted polymer grafted to the cellulose by living radical polymerization. J Membr Sci 233, 169-173, 2004
Aoyagi S, Hayama M, Hasegawa U, et al: Estimation of protein adsorption on dialysis membrane by means of TOF-SIMS imaging. J Membr Sci 236, 91-99, 2004
Aoyagi S, Hayama M, Hasegawa U, et al: TOF-SIMS imaging of protein adsorption on dialysis membrane. Appl Surf Sci 231-232, 411-415, 2004
Ebara M, Yamato M, Aoyagi T, et al: Immobilization of cell-adhesive peptides to temperature-responsive surfaces facilitates both serum-free cell adhesion and noninvasive cell harvest. Tissue Eng 10, 1125-1135, 2004
Yoshimi Y, Kamada M, Ohkawara Y, et al: Improvement of hydrogen peroxide sensitivity by an electrochemiluminescent mothod with luminol using polyion adsorption onto the electrode. Electrochemistry 72, 747-750, 2004
Ebara M, Yamato M, Nagai S, et al: Incorporation of new carboxylate functionalized co-monomers to temperature-responsive polymer-grafted cell culture surfaces. Surf Sci 570, 134-141, 2004
Hayama M, Miyasaka T, Mochizuki S, et al: Optimum dialysis membrane for endotoxin blocking. J Membr Sci 219, 15-25, 2003
Ebara M, Yamato M, Hirose M, et al: Copolymerization of 2-carboxyisopropylacrylamide with N-isopropylacrylamide accelerates cell detachment from grafted surfaces by reducing temperature. Biomacromolecules 4, 344-349, 2003
Aoyagi S, Imai R, Sakai K, et al: Reagentless and regenerable immunosensor for monitoring of immunoglobulin G based on non-separation immunoassay. Biosens Bioelectron 18, 791-795, 2003
Nagase K, Kohori F, Sakai K: Development of a compact artificial gill using concentrated hemoglobin solution as the oxygen carrier. J Membr Sci 215, 281-292, 2003
Kobayashi J, Kikuchi A, Sakai K, et al: Cross-linked thermoresponsive anionic polymer-grafted surfaces to separate bioactive basic peptides. Anal Chem 75, 3244-3249, 2003
Aoyagi S, Kudo M, Hayama M, et al: TOF-SIMS imaging of protein adsorption on dialysis membrane by mean of information entropy. e-J Surf Sci Nanotech 1, 67-71, 2003
Nagase K, Kohori F, Sakai K: Designing an artificial gill using oxygen carrier solution for effective supply of oxygen to underwater closed spaces. Journal of Research in Science and Engineering 1, 31-36, 2003
Endo K, Miyasaka T, Mochizuki S, et al: Development of a superoxide sensor by immobilization of superoxide dismutase. Sensors and Actuators B 83, 30-34, 2002
Hayama M, Kohori F, Sakai K: AFM observation of small surface pores of hollow-fiber dialysis membranes using highly sharpened probe. J Membr Sci 197, 243-249, 2002
Kohori F, Yokoyama M, Sakai K, et al: Process design for efficient and controlled drug incorporation into polymeric micelle carrier system. J Control Release 78, 155-163,2002
Aoyagi S, Miyasaka T, Yoshimi Y, et al: A new reagentless immunosensor for measuring IgG concentration in human plasma based on fluorescence-enhancement immunoassay. J Artif Organs 5, 60-63, 2002
Nagase K, Matsuda N, Sakai K: Optimum control of oxygen affinity of hemoglobin as an oxygen carrier solution for an artificial gill. J Artif Organs 5, 44-49, 2002
Miyasaka T, Endo K, Sakai K: Electrochemiluminescent measurement of human serum concentration in dialysate. J Artif Organs 5, 18-23, 2002
Fukutomi I, Sakai H, Takeoka S, et al: Carbonylation of oxyhemoglobin solution (HbO2→HbCO) using a membrane oxygenator. J Artif Organs 5, 102-107, 2002
Kobayashi J, Kikuchi A, Sakai K, et al: Aqueous chromatography utilizing hydrophobicity-modified anionic temperature-responsive hydrogel for stationary phases. J Chromatogr A 958, 109-119, 2002
Miyasaka T, Matsuda Y, Sakai K, et al: Development of a contamination free 6 valve injector inline monitoring system for endotoxin measurement in dialysate. ASAIO J 48, 389-393, 2002
Ishiwata K, Yamamoto K, Kohori F, et al: Technical evaluation of dialysate flow in a hollow-fiber dialyzer. J Artif Organs 5, 251-256, 2002
Hayama M, Miyasaka T, Mochizuki S, et al: Visualization of distribution of endotoxin trapped in an endotoxin-blocking filtration membrane. J Membr Sci 210, 45-53, 2002
Yoshimi Y, Ohdaira R, Iiyama C, et al: “Gate effect” of thin layer of molecularly-imprinted poly(methacrylic acid-co-ethyleneglycol dimethacrylate). Sens actuators 73, 49-53, 2001
Ebara M, Aoyagi T, Sakai K, et al:The incorporation of carboxylate groups into temperature-responsive poly(N-isopropylacrylamide-based hydrogels promotes rapid gel shrinking. J Polym Sci A 39, 335-342, 2001
Matsuda N, Sakai K, Nakamura T, et al: Temperature-controlled enhancement of oxygen uptake from water using oxygen carrier solution. J Membr Sci 184, 17-26, 2001
Aoyagi S, Suzuki Y, Sakai K, et al: Transient measurement with an enzyme-immobilized electrode undergoing protein adsorption. Electrochemistry 69, 251-253, 2001
Kobayashi J, Kikuchi A, Sakai K, et al: Aqueous chromatography utilizing pH-/temperature-responsive polymer stationary phases to separate ionic bioactive compounds. Anal Chem 73, 2027-2033, 2001
Nakajima A, Miyasaka T, Sakai K, et al: Determination of effective charge density of hollow-fiber dialysis membranes and its effects on phosphate ion permeability. J Membr Sci 187, 129-139, 2001
Aoyagi S, Iwata T, Miyasaka T, et al: Determination of human serum albumin by chemiluminescence immunoassay with luminol using a platinum-immobilized flow-cell. Anal Chim Acta 436, 103-108, 2001
Aoyagi S, Yamazaki M, Miyasaka T, et al: Clarification of enhanced hydroxyl radical production in fenton reaction with ATP/ADP based on luminol chemiluminescence. J Chem Eng Japan 34, 956-959, 2001
Hattori K, Yoshimi Y, Sakai K: Gate effect of cellulosic dialysis membrane grafted with molecularly imprinted polymer. J Chem Eng Japan 34, 1466-1469, 2001
Suzuki Y, Kohori F, Sakai K: Computer-aided design of hollow-fiber dialyzers. J Artif Organs 4, 326-330, 2001
Aoyagi T, Ebara M, Sakai K, et al: Novel bifunctional polymer with reactivity and temperature sensitivity. J Biomater Sci Polym Ed 11, 101-110, 2000
Uchida K, Sakai K, Ito E, et al: Temperature-dependent modulation of blood platelet movement and morphology on poly(N-isopropylacrylamide)-grafted surfaces. Biomaterials 21, 923-929, 2000
Uchida K, Sakai K, Kwon OH, et al: Temperature-sensitive poly(N-isopropylacrylamide)-grafted surfaces modulate of blood platelet interactions. Macromol Rapid Commun 21, 169-173, 2000
Uchida K, Yamato M, Ito E, et al: Two different types of nonthrombogenic surfaces: PEG suppresses platelet adhesion ATP-independently but HEMA-st block copolymer requires ATP consumption of platelets to prevent adhesion. J Biomed Mater Res 50, 585-590, 2000
Matsuda N, Sakai K: Blood flow and oxygen transfer rate of an outside blood flow membrane oxygenator. J Membr Sci 170, 153-158, 2000
Sakai K: Dialysis membranes for blood purification. Front Med Biol Eng 10, 117-129, 2000
Kanamori T, Habu T, Shinbo T, et al: Difference in solute diffusivity in crosslinked collagen gels prepared under various conditions. Mater Sci Eng C 13, 85-89, 2000
Ebara M, Aoyagi T, Sakai K, et al: Introducing reactive carboxyl side chains retains phase transition temperature sensitivity in N-isopropylacrylamide copolymer gels. Macromolecules 33, 8312-8316, 2000
Matsuda N, Sakai K, Yamamoto K, et al: Effects of hollow fiber packing fraction on blood flow pattern and gas transfer rate of an intravascular oxygenator (IVOX). J Membr Sci 179, 231-241, 2000
Miyasaka T, Iijima K, Sakai K, Yoshimi Y, Aketagawa J, Tamura H, Tanaka S : Development of a stopped flow reactor for the rapid, high sensitivity measurement of endotoxin concentration in dialysate. ASAIO J, 45, 104-108, 1999
Tsuji M, Sakai K : Theoretical comparison of filtration by the renal glomernlus and artificial membranes. ASAIO J, 45, 98-103, 1999
Yakushiji T, Sakai K., Kikuchi A, Aoyagi T, Sakurai Y, Okano T : Effects of cross-linked structure on temperature-responsive hydrophobic interaction of poly(N-isopropylacrylamide) hydrogel-modified surfaces with steroids. Anal. Chem, 71, 1125-1130, 1999
Matsuda N, Sakai K : Technical evaluation of oxygen transfer rates of fish gills and artificial gills. ASAIO J, 45, 293-298, 1999 
Tsunoda N, Kokubo K, Sakai K, Fukuda M, Miyazaki M, Hiyoshi T : Surface roughness of cellulose hollow fiber dialysis membranes and platelet adhesion.  ASAIO J, 45, 418-423, 1999 
Kaneko Y, Nakamura S, Sakai K, Kikuchi A, Aoyagi T, Sakurai Y, Okano T: Synthesis and swelling-deswelling kinetics of poly(N-isopropylacrylamide) hydrogels grafted with LCST modulated polymers. J Biomater Sci Polym Ed, 10, 1079-1091, 1999 
Kohori F, Sakai K, Aoyagi T, Yokoyama M, Yamamoto M, Sakurai Y, Okano T: Control of adriamycin cytotoxic activity using thermally responsive polymeric micelles composed of poly(N-isopropyl-acrylamide-co-N, N-dimethylacrylamide)-b-poly(D,L-lactide). Colloids Surf B, 16, 195-205, 1999 
Matsuda N, Nakamura M, Sakai K, Kuwana K, Tahara K: Theoretical and experimental evaluation for blood pressure drop and oxygen transfer rate in outside blood flow membrane oxygenator. J Chem Eng Japan, 32, 752-759, 1999 
Kaneko Y, Nakamura S, Sakai K, et al: Rapid Deswelling Response of poly(N-isopropylacrylamide) Hydrogels by the Formation of Water Release Channels Using Poly(ethylene oxide) Graft Chains. Macromolecules, 31, 6099-6105, 1998
Kaneko Y, Sakai K, Okano T: Temperature-Responsive Hydrogels as Intelligent Materials. Biorelated Polymers and Gels, pp29-69, 1998
Yakushiji T, Sakai K, Kikuchi A, et al: Graft Architectural Effects on Thermoresponsive Wettability Changes of Poly(N-isopropylacrylamide)-Modified Surfaces. Langmuir, 14, 4657-4662, 1998
Miyasaka T, Jinbo Y, Sakai K, et al: Determination of Glucose Concentration by Electroluminescence of an Indium-tin Oxide Electrode. Chemical Engineering Food and Bioproducts Processing (Trans IChemE, Part C), 76, 102-106, 1998
Kanamori T, Shinbo T, Sakai K: Size of Polymeric Particles Forming Hemodialysis Membranes Determined from Water and Solute Permeabilities. Journal of Applied Polymer Science, 67, 833-840, 1998
Miyasaka T, Yoshimi, Sakai K: Transient Measurement of Glucose Using On-off Controllable Enzyme Electrode with Polypyrrole Membrane. Journal of Chemical Engineering of Japan, 31, 29-34, 1998
Waki M, Nojiri C, Hayashi H, et al: Surface Modification Techniques for the Artificial Heart. Heart Replacement, Artificial Heart 6, pp.118-125, 1998
Kanamori T, Shinbo T, Sakai K: Feasibility of wearable artificial kidney using presently commercially available hollow-fiber membrane. J Artif Organs, 1, 69-75, 1998
Kohori F, Sakai K, Aoyagi T, et al: Preparation and characterization of thermally responsive block copolymer micelles comprising poly(N-isopropylacrylamide-b-DL-lactide) . J Control Release, 55, 87-98, 1998
Kokubo K, Sakai K, Okada A, et al: Evaluation of the structure of asymmetric hollow-fiber dialysis membranes by dye adsorption. Biochem Eng J, 2, 45-52, 1998
Fukuda M,Kokubo K, Sakai K, et al: Anisotropic differences in solute transfer rate through asymmetric membranes for blood purification accompanied by filtration. Biochem Eng J, 2, 127-136, 1998
Kokubo K, Sakai K : Evaluation of dialysis membranes using a tortuous pore model. AIChE J, 44, 2607-2619, 1998
Kaneko Y, Nakamura S, Sakai K, et al: Deswelling mechanism for comb-type grafted poly(N-isopropylacrylamide) hydrogels with rapid temperature responses. Polym Gels Networks, 6, 333-345, 1998
Yoshimi Y, Sakai K : Analysis of reaction of luminol at an indium-tin oxide anode by cyclic voltammetry. J Chem Eng Japan, 30, 535-538, 1997
Miyasaka T, Taniyama Y, Sakai K, Yoshimi Y : Development of a glucose sensor with on/off control of enzyme activity without the effects of protein adsorption.  ASAIO J, 43, M505-M509,1997
Mizumoto D, Nojiri C, Inomata Y, Onishi M, Waki M, Kido T, Sugiyama T, Senshu K, Uchida K, Sakai K, Akutsu T : Comparative blood compatibility of polyether vs polycarbonate urethanes by epifluorescent video microscopy. ASAIO J, 43, M500-M504, 1997
Saito N, Nojiri C, Kuroda S, Sakai K : Photochemical grafting of alpha-propylsulphate poly(ethylene oxide) on polyurethane surfaces and enhanced antithrombogenic potential. Biomaterials, 18, 1195-1197, 1997
Kanamori T, Sakai K: Comparison between urea removal in mathematical kinetic model. Int J Artif Organs, 20, 158-162, 1997
Kokubo K, Ishii A, Miura A, Suzuki T, Sakai K : Estimating solute concentrations in blood from solute concentrations in dialysate and apparent distribution volume of solutes. Artif Organs Today, 5, 113-123, 1996 
Kanamori T, Sakai K : Effect of mass transfer between plasma and erythrocyte interior on evaluating dialyzer performance. Artif Organs Today, 5, 101-112, 1996 
Kokubo K, Taguchi M, Sakai K : Changes in charge and ion permeability of PAN-DX dialysis membrane caused by protein adsorption. Chem Eng J, 62, 73-79, 1996 
Kanamori K, Takeshita T, Sakai K : Mass transfer of antibiotics adsorbed by human serum albumin in hemodialyzers. Biotechnol Prog, 12, 503-509, 1996 
Kokubo K, Yakushiji T, Sakai K : Diffusive permeability of asymmetrical polysulfone dialysis membranes dependent on pore size and pore size distribution of their skin and supporting layers. Artif Organs Today, 5, 185-195, 1996 
Yoshimi Y, Haramoto H, Miyasaka T, Sakai K : Cathodic electrochemiluminescence of luminol enhanced by antibody-antigen reaction. J Chem Eng Japan, 29, 851-857, 1996 
Yoshimi Y, Iguchi S, Miyasaka T, Sakai K : Electroluminescence of indium-tin oxide in an alkaline  solution of hydrogen peroxide. J Chem Eng Japan, 29, 1063-1066, 1996 
Kaneko Y, Sakai K, Kikuchi A, Sakurai Y, Okano T: Fast swelling and deswelling kinetics of comb-type grafted poly (N-isopropyl-acrylamide) hysrogels. Macromol Symp, 109, 41-53, 1996 
Kanamori T, Sakai K, Fukuda M, Yamashita Y : Preferable structure of poly(ethylene glycol) for grafting onto a cellulosic membrane to increase hemocompatibility without reduction in solute permeability of the membrane. J Appl Polym Sci, 55, 1601-1605, 1995 
Yoshida R, Uchida K, Kaneko Y, Sakai K, Kikuchi A, Sakurai Y, Okano T: Comb-type grafted hydrogels with rapid deswelling response to temperature changes. Nature, 374, 240-242,1995 
Kanamori T, Fukuda M, Sakai K: Structural analysis of hemodialysis membranes by evaluating distribution volume of water contained in the membranes. J Colloid Interface Sci, 171, 361-365, 1995 
Kanamori T, Sakai K: An estimate of beta 2-microglobulin deposition rate of uremic patients on hemodialysis using a mathematical kinetic model, Kidney Int, 47, 1453-1457, 1995 
Kaneko Y, Yoshida R, Sakai K, Sakurai Y, Okano T: Temperature-responsive shrinking kinetics of poly(N-isopropylacrylamide) copolymer gels with hydrophilic and hydrophobic comonomers. J Membr Sci, 101, 13-22, 1995 
Yoshimi Y, Yotsumoto M, Sakai K: A novel method for the continuous measurement of endotoxin  concentration. ASAIOJ, 41, 68-71, 1995 
Aoyagi S, Yoshimi Y, Sakai K, Aketagawa J, Tanaka S:  Development of a new endotoxin sensor with intermittent injection of limulus reagent for continuous monitoring of dialysate fluid. ASAIO J, 41, M601-M604, 1995 
Kaneko Y, Sakai K, Kikuchi A, Yoshida R, Sakurai Y, Okano T: Influence of freely mobile grafted chain length on dynamic properties of comb-type grafted poly(N-isopropylacrylamide) hydrogels. Macromolecules, 28, 7717-7723, 1995 
Nojiri C, Kuroda S, Saito N, Park KD, Hagiwara K,  Senshu K, Kido T, Sugiyama T, Kijima T, Kim YH, Sakai K, Akutsu T: In vitro studies of unmobilized heparin and sulfonated polyurethane using epifluorescent video microscopy. ASAIO J, 41, M389-M394, 1995

Sakai K: Determination of pore size and pore size distribution. 2. Dialysis Membranes. J Membr Sci 96, 91-130, 1994
Yoshida R, Okuyama Y, Sakai K, Okano T, Sakurai Y: Sigmoidal swelling profiles for temperature-responsive poly (N-isopropylacrylamide-co-butyl methacrylate) hysrogels. J Membr Sci, 89, 267-277, 1994
Yoshida R, Sakai K, Okano T, Sakurai Y: Modulating the phase transition temperature and thermosensitivity in N-isopropylacrylamide copolymer gels. J Biomater Sci Polym Ed, 6, 585-598, 1994
Yoshida R, Kaneko Y, Sakai K, Okano T, Sakurai Y, Bae YH, Kim SW: Positive thermosensitive pulsatile drug release using negative thermosensitive hydrogels. J Control Release, 32, 97-102, 1994
Yoshida R, Sakai K, Okano T: Advances in polymeric hydrogels for control of drug release. Trends in Chemical Engineering, 2, 59-73, 1994  
Kawagoishi N, Nojiri C, Senshu K, Kido T, Nagai H,  Kanamori T, Sakai K, Koyanagi H, Akutsu T: In vitro evaluation of platelet and biomaterial interactions in an epifluorescent video microscopy combined with a parallel plate flow cell. Artif Organs, 18, 588-595, 1994  
Kanamori T, Sakai K, Awaka T, Fukuda M: An improvement on the method of determining the solute permeability of hollow fiber dialysis membranes photometrically using optical fibers and comparison of the method with ordinary techniques. J Membr Sci, 88, 159-165, 1994 
Haramoto H, Kokubo K, Sakai K, Kuwata K, Nakanishi  H: An artificial gill system for oxygen uptake from water using perfluorooctylbromide. ASAJO J, 40, M803-M807, 1994 
Yoshimi Y, Marutani H, Sakai K, Aketagawa J: A new procedure for stable quantification of endotoxin in dialysate fluid using limulus reagent. ASAJO J, 40, M808-M810, 1994  
Kanamori T, Sakai K, Awaka T, Fukuda M: Mass transfer in laminar flows around single hollow fiber membranes for hemodialysis. J Chem Eng Japan, 27, 830-832, 1994
Hosoya N, Kanamori T, Sakai K: Optimal design of a high-performance dialyzer involving backfiltration. Artif Organs Today 2, 287-298, 1993
Okuyama Y, Yoshida R, Sakai K, Okano T, Sakurai Y: Swelling controlled zero order and sigmoidal drug release from thero-responsive poly (N-isopropylacrylamide-co-butyl methacrylate) hydrogel. J Biomater Sci Polym Ed, 4, 545-556, 1993

Nojiri C, Nakahama S, Senshu K, Okano T, Kawagoishi N, Kido T, Sakai K, Koyanagi H, Akutsu T: A new amphiphilic block co-polymer with improved elastomeric properties for application in various medical devices. ASAJO J, 39, M322-M326, 1993  
Sakai K, Yanagisawa M, Hosoya N, Ohmura T, Sakagami M, Kuwana K, Nakanishi H: Comparison of oxygenation and flow characteristics of inside and outside blood flow membrane oxygenators. Artif Organs Today, 3, 57-80, 1993  
Yoshimi Y, Sakai K: Development of a sensitive method for continuous determination of hydrogen peroxide concentration by electrochemi-luminescence. Food Bioprod Proc (Trans IChemE, Part C), 71, 279-284, 1993
Sakai K, Kanamori T, Nakasato S: Usefulness of KT/V in comparing the adequacy of hemodialysis and continuous ambulatory peritoneal dialysis. Artif Organs Today, 3, 81-83, 1993  
Suzuki Y, Kanamori T, Sakai K: Zeta potential of hollow fiber dialysis membranes and its effects on hydrogen phosphate ion permeability. ASAIOJ, 39, M301-M304, 1993
Ogasawara K, Tsuda S, Ozawa K, Sakai K: Protein adsorption on microporous membranes for plasma separation and its effects on flux decay. Chem Eng J, 48, B1-B7, 1992
Ogasawara K, Sakai K: Utilization of microporous glass membranes in plasma separation. Artif Organs Today, 2, 55-75, 1992
Yoshida R, Sakai K, Okano T, Sakurai Y: Surface-modulated skin layers of thermal responsive hydrogels as on-off switches II drug permeation. J Biomater Sci Polym Ed, 3, 243-252, 1992
Mineshima M, Watanuki M, Yamagata K, Era K, Nakazato S, Suga H, Agishi T, Ota K, Sakai K, Fukui K: Development of continuous recirculating peritoneal dialysis using a double lumen catheter. Trans Am Soc Artif Intern Organs, 38, M377-M381, 1992 
Yoshida R, Sakai K, Okano T, Sakurai Y: Drug release profiles in the shrinking process of thermoresponsive poly (N-isopropylacrylamide-coalkyl methacrylate) gels. Ind Eng Chem Res, 31, 2339-2345, 1992
Shimizu M, Kanamori T, Sakai K, Igoshi T, Yoshida M: New polymer alloy dialysis membranes with varying permeabilities and sievings. Trans Am Soc Artif Intern Organs, 38, 784-787, 1992
Fukuda M, Hosoya N, Kanamori T, Sakai K,  Nishikido J, Watanabe T, Fushimi F: Determination of optimal fiber density of conventional and high performance dialyzers. Artif Organs Today, 2, 205-214, 1992
Ogasawara K, Yoshida R, Sakai K: Effects of hematocrit on filtrate flux of microporous glass membranes for bovine blood. J Chem Eng Japan, 24, 118-120, 1991
Mineshima M, Agishi T, Ota K, Sakai K: Technical aspects of membrane plasma separation and fractionation. Artif Organs Today, 1, 135-149, 1991
Ikeda Y, Handa M, Kawano K, Kamata T, Murata M, Araki Y, Itagaki I, Sakai K, Ruggeri ZM: The role of von willebrand factor and fibrinogen in platelet aggregation under varying shear stress. J Clin Invest, 87, 1234-1240, 1991
Yoshida R, Sakai K, Okano T, Sakurai Y: A new model for zero-order drug release I hydrophobic drug release from hydrophilic polymeric matrices. Polym J, 23, 1111-1121, 1991
Yoshida R, Sakai K, Okano T, Sakurai Y, Bae YH, Kim SW: Surface-modulated skin layers of thermal responsive hydroge]s as on-off switches I drug release. J Biomater Sci Polym Ed, 3, 155-162, 1991
Tatsuguchi T, Sakai K, Nishikido J, Yamamoto T, Fushimi F, Nishida O: Newly-developed regenerated cellulose dialysis membranes for efficient removal of beta-2-microglobulin. Artif Organs, 14, 215-216, 1991
Hagiwara K, Kanamori T, Sakai K: Diffusive permeability for inorganic phosphate ion of cuprophan and hemophan membranes. Blood Purifi, 9, 51, 1991

Kanamori T, Sakai K: Utility of short-time and frequent hemodialysis treatments from engineering points of view (in Japanese). Jinko Zouki 20, 1411-1420, 1991
Fukuyama M, Kawakami K, Sakai K, ltagaki I, Kawano K, Handa M, Ikeda Y: Potentiation by heparin of shear-induced platelet aggregation. Artif Organs, 14, 76-79, 1990
Mineshima M, Agishi T, Ota K, Sakai K: Kinetics in membrane plasma separation and fractionation. Artif Organs, 14, 11-15, 1990
Hosoya N, Sakai K: Backdiffusion rather than backfiltration enhances endotoxin transport through highly permeable dialysis membranes. Trans Am Soc Artif Intern Organs, 36, M311-M313, 1990
Okada M, Watanabe T, Imamura K, Tsurumi T, Suma Y, Sakai K: Ionic strength affects diffusive permeability to an inorganic phosphate ion of negatively charged dialysis membranes. Trans Am Soc Artif Intern Organs, 36, M324-M327, 1990
Sakagami M, Kuwana K, Nakanishi H, Sakai K: Improvements in determination of cardiac output with a swan-ganz catheter. Trans Am Soc Artif Intern Organs, 36, M684-M686, 1990
Fukuyama M, Kawakami K, Sakai K, Itagaki I, Kawano K, Handa M, Ikeda Y: Shear stress induces not only platelet aggregation but also platelet-tumor cell interaction. Trans Am Soc Artif Intern Organs, 36, M189-M191, 1990
Kawakami K, Fukuyama M, Ogasawara K, Sakai K, ltagaki I, Kawano K, Handa M, Ikeda Y: Change of intracellular calcium ions during shear induced platelet aggregation. Trans Am Soc Artif Intern Organs, 36, M696-M699, 1990
Takesawa S, Saito H, Hidai H, Suzuki M, Sakai K : Measurement of back clearance. Trans Am Soc Artif Intern Organs, 36, M441-M443, 1990
Itagaki I, Fukuyama M, Kawakami K, Sakai K, Kawano K, Handa M, Ikeda Y: Changes in intracellular Ca2+ concentrations during shear-induced platelet aggregation. Artif Organs, 14, 275-277, 1990
Kawakami K, Fukuyama M, Sakai K, ltagaki I, Kawano K, Handa M, Ikeda Y: Shear stress dependent selectivity in adhesive proteins required for platelet aggregation. Artif Organs, 14, 97-100, 1990
Hosoya N, Sakai K: Internal filtration (in Japanese). Clin Eng 1, 454-459, 1990
Ozawa K, Ohashi K, Ide T, Sakai K: Technical evaluation of newly-developed inorganic membranes for plasma fractionation. Int J Artif Organs, 12, 195-199, 1989
Sakai K, Nagase M, Tsuda S: Adsorption of beta2-microglobulin on PMMA, PAN and cellulosic membranes. Chem Eng J, 42, B39-B49, 1989
Okada M, Takesawa S, Watanabe T, Imamura K, Tsurumi T, Suma Y, Sakai K: Effects of zeta potential on the permeability of dialysis membranes to inorganic phosphate. Trans Am Soc Artif Intern Organs, 35, 320-322, 1989
Ohmura T, Tatsuguchi T, Nishikido J, Yamamoto T, Fushimi F, Nishida O, Sakai K: A new method of determining the solute permeability of hollow-fiber dialysis membranes by means of laser light traveling along optic fibers. Trans Am So. Artif Intern Organs, 35, 601-603, 1989
Ogasawara K, Kushiya F, Sakai K: Filtration characteristics of rotating plasma filter composed of flat nylon membrane. Membrane, 14, 50-53, 1989
Fukuyama M, Sakai K, Itagaki I, Kawano K, Murata M, Kawai Y, Watanabe K , Handa M , Ikeda Y: Continuous measurement of shear-induced platelet aggregation. Thromb Res, 54, 253-260, 1989
Sakai K, Ozawa K, Ohashi K, Yoshida R, Sakurai H: Low-temperature plasma separation by cross-flow filtration with microporous glass membranes. Ind Eng Chem Res, 28, 57-64, 1989
Sakai K: Technical determination of optimal dimensions of hollow fiber membranes for clinical dialysis. Nephrol Dial Transplant, 4, 73-77, 1989
Sakai K: Structure and permeability of dialysis membranes sterilized by various methods. J Biomater Appl, 4, 71-101, 1989
Sakai K, Nagase M, Tsuda S: Adsorption of β2-microgloblin on PMMA, PAN, cellulosic membranes. Biochem Eng J 42, 39-45, 1889
Sakai K, Chiba H, Naitoh A: Determination of the pore radius of regenerated cellulose membranes by a dyeing technique. J Membr Sci, 37, 101-112, 1988
Sakai K, Ohashi H, Naitoh A: Effects of blood contact on the properties of tubular dialysis membranes. Chem Eng J, 38, Bl-B6, 1988  
Ikeda Y, Murata M, Araki Y, Watanabe K, Ando Y, Itagaki I, Mori Y, Ichitani M, Sakai K: Importance of fibrinogen and platelet membrane glycoprotein IIb/IIIA in shear-induced platelet aggregation. Thromb Res, 51, 157-163, 1988
Sakai K, Takesawa S, Mimura R, Ohashi H: Determination of pore radius of hollow fiber dialysis membranes using tritium-labeled water. J Chem Eng Japan, 21, 207-210, 1988
Takesawa S, Terasawa M, Sakagami M, Kobayashi T, Hidai H, Sakai K: Nondestructive evaluation by X-ray computed tomography of dialysate flow patterns in capillary dialyzers. Trans Am Soc Artif lntern Organs, 34, 794-799, 1988
Ohashi K, Tashiro K, Kushiya F, Matsumoto T, Yoshida S, Endo M, Horio T, Ozawa K, Sakai K: Rotation-induced Taylor vortex enhances filtrate flux in plasma separation. Trans Am Soc Artif Intern Organs, 34, 300-307, 1988
Naitoh A, Tatsuguchi T, Okada M, Ohmura T, Sakai K: Removal of beta-2-microglobulin by diffusion alone is feasible using highly permeable dialysis membranes. Trans Am Soc Artif Intern Organs, 34, 630-634, 1988
Ozawa K, Sakurai H, Ohashi K, Yoshida R, Sakai K, Nishioka T, Matoba S, Yaginuma T, Kato H: Effects of pore size on filtration characteristics in plasma separation with microporous glass membranes. Therapeutic Plasmapheresis, 7, 196-199, 1988
Sakai K, Koyano T, Murai T, Tamura M: Effects of temperature and concentration polarization on water vapor permeability for blood in membrane distillation. Chem Eng J, 38, B33-B39, 1988
Ozawa K, Mimura R, Sakai K: Filtration characteristics of membranes for plasma separation and changes in membrane structure after blood contact. J Chem Eng Japan, 20, 345-351, 1987
Sakai K, Takesawa S, Mimura R, Ohashi H: Structural analysis of hollow fiber dialysis membranes for clinical use. J Chem Eng Japan, 20, 351-356, 1987
Takesawa S, Ohashi H, Hidai H, Sakai K: Effects of membrane structure on removal of low molecular weight proteins. Artif Organs, 11, 495-497, 1987
Sakai K, Ozawa K, Mimura R, Ohashi H: Comparison of methods for characterizing microporous membranes for plasma separation. J Membr Sci, 32, 3-17, 1987
Takesawa S, Satoh S, Hidai H, Sekiguchi M, Sakai K: Degradation by gamma irradiation of regenerated cellulose membranes for clinical dialysis. Trans Am Soc Artif lntern Organs, 10, 584-587, 1987
Sakai K, Tashiro K, Sakurai H, Kanamori T, Torii M, Ohshima M, Higuchi J, Sakai T : Factors affecting plasma and blood viscosity and corresponding abnormalities in renal failure patients. Chem Eng J, 36, B7-B13, 1987
Matsuhisa S, Takesawa S, Sakai K: Binary-solute adsorption of dosed drugs on serum albumin. Chem Eng J, 34, B21-B27, 1987  
Takesawa S, Ohmi S, Sekiguchi M, Shitaokoshi S, Takahashi T, Hidai H, Sakai K: Varying methods of sterilisation, and their effects on the structure and permeability of dialysis membranes. Nephrol Dial Transplant, 1, 254-257, 1987
Sakai K, Muroi T, Ozawa K, Takesawa S, Tamura M, Nakane T: Extraction of solute-free water from blood by membrane distillation. Trans Am Soc Artif Intern Organs, 32, 397-400, 1986
Sakurai H, Ozawa K, Takesawa S, Sakai K: Design of a plasma separator using ceramic membranes. Trans Am Soc Artif Intern Organs, 32, 410-413, 1986
Mineshima M, Hasuo H, Kaneko I, Era K, Agishi T, Ota K, Sakai K: Relationship between Staverman's reflection and sieving coefficients in a plasma fractionator. Trans Am Soc Artif Intern Organs, 32, 418-421, 1986
Sakai K, Takesawa S: Removal estimation of middle molecular substances (MM) with high speed liquid chromatography. J Chem Eng Japan, 18, 8-13, 1985
Mineshima M, Yamagata K, Era K, Agishi T, Ota K,  Sakai K: Kinetic comparison of hemofilters for continuous arteriovenous hemofiltration (CAVH). Trans Am Soc Artif Intern Organs, 31, 660-663, 1985
Sakai K, Mineshima M: Performance evaluation of a module in artificial kidney system. J Chem Eng Japan,  17, 198-203, 1984
Sakai K, Mineshima M: Therapeutic parameters for solute removal m hemodialysis. J Chem Eng Japan, 16, 320-323, 1983
Sakai K, ltagaki I, Mineshima M, Matsuda K, Suzuki M, Azuma N, Sakai T, Nanbu M: Water shift and solute transfer in osmotic hemopurification using high sodium fluid. Artif Organs, 5(suppl), 359-363, 1981

解説記事
Takehiro Miyasaka, Kiyotaka Sakai: Application of mathematical analysis on dialysis. Journal of Artificial Organs https://doi.org/10.1007/s10047-022-01359-8
酒井清孝：研究する上で大切なこと～研究とは格闘技である～、日本血液浄化技術学会雑誌、29, 214-215, 2021
酒井清孝、福田　誠、滑川亘希：血液浄化膜の誕生と進化・今後への期待、日本急性血液浄化学会雑誌、10, 73-88, 2019
小林修三、酒井清孝、天野　泉、金子岩和：医工学治療の軌跡、そして今後の展望（第３５回学術集会「３０周年特別座談会」）、医工学治療、31, 151-158, 2019
酒井清孝：Kolff Kidney（回転ドラム型人工腎臓）の誕生とその検証、日本急性血液浄化学会雑誌、9, 71-91, 2018
酒井清孝：日本血液浄化技術学会発足30周年に寄せて、日本血液浄化技術学会雑誌、26, 22, 2018
酒井清孝：メディカル・エッセイ　学会懇親会参加のご利益、日本透析医会雑誌、33, 193-194, 2018
酒井清孝：Stewart Kidneyの誕生とその検証、医工学治療、30, 3-7, 2018
酒井清孝：日本化学会「化学と教育」巻頭言　化学教育徒然草　ー技術は人なりー、化学と教育、65,369, 2017
酒井清孝：人体は小さな化学プラント、次世代への羅針盤、Harima Quarterly、No.132, 2017 Summer
酒井清孝：生体拡散の概念の検証、日本血液浄化技術学会雑誌、24, 37-42, 2016
酒井清孝：血液浄化器はどのように誕生し、高性能化を求めてどのように進化したか、最新透析医療ー先端技術との融合ー、27-36, 2016
酒井清孝：血液浄化器の発展の歴史、新ハイパフォーマンスダイアライザ―UptoDate、2-15, 2016
酒井清孝：血液浄化器のこれまでとこれから、人工臓器、43, 214-227, 2014
酒井清孝：膜分離の基礎、臨床透析、30, 87-92, 2014
酒井清孝：血液浄化装置、Clinical Engineering、25, 1023-1030, 2014
酒井清孝：透析膜・透析器開発の変遷と今後の展望、医工学治療、25, 3-6, 2013
Sakai K: Blood purification and the role of membrane. J Chin Inst Chem Engrs, 28, 427-434, 1997
Sakai K: Artificial kidney engineering-dialysis membrane and dialyzer for blood purification-. J Chem Eng Japan, 30, 587-599, 1997
Sakai K: Determination of pore size and pore size distribution 2 dialysis membrane. J Membr Sci, 96, 91-130, 1994
Yoshida R, Sakai K, Okano T, Sakurai Y: Pulsatile drug delivery systems using hydrogels. Adv Drug Deliv Rev, 1, 85-108, 1993

 図書 
日本医学史学会編、坂井健雄編集委員長：医学史事典、分担執筆、丸善出版、2022
酒井清孝監訳：生体内移動論、朝倉書店、2021
織田成人、酒井清孝編集：血液浄化とそれを支える基盤技術、東京医学社、2020
酒井清孝：血液浄化装置（人工腎臓）の開発とその高性能化 in 血液浄化とそれを支える基盤技術、東京医学社、pp.46-60, 2020
酒井清孝：血液浄化器に関する歴史 in 日本透析医学会50周年記念誌、日本透析医学会、pp.205-208, 2018
酒井清孝、宮坂武寛、福田　誠、薬師寺大二：なぜ？から学ぶ血液浄化７７、東京医学社、2017
酒井清孝：血液浄化器発展の歴史 in これからの透析医療のための新ハイパフォーマンスダイアライザ UptoDateーダイアライザとヘモダイアフィルタ、東京医学社、pp.2-15, 2016
酒井清孝：血液浄化器はどのように誕生し、高性能化を求めてどのように進化したか in 最新透析医療ー先端技術との融合ー、医薬ジャーナル社、pp.07-36, 2016
Nagase K, Kohori F, Sakai K: Efficiency of biological and artificial gills, In Kato N, Ayers J, Morikawa H (ed.), Bio-mechanisms of Swimming and Flying, pp.188-199, Springer-Verlag Tokyo, 2004
Ebara M, Kikuchi A, Sakai K, Okano T: Fast shrinkable materials (chapter 12). In Yui N, Mrsny RJ, Park K (eds),  Reflexive Polymers and Hydrogels-Understanding and Designing Fast Responsive Polymeric-, pp.219-244, CRC Press, 2004
Waki M, Nojiri C, Hayashi H, Kido T, Saito N, Sugiyama T, Ishihara K, Nakabayashi N, Kishida A, Akashi M, Sakai K, Akutsu T: Surface modification techniques for the artificial heart. In Akutsu T, Koyanagi H (eds), Heart Replacement, Artificial Heart 6, pp.118-125, Springer-Verlag Tokyo, 1998
Kaneko Y, Sakai K, Okano T: Temperature-responsive hydrogels as intelligent materials. In Okano T (ed), Biorelated Polymers and Gels, pp.29-69, Academic Press, 1998
Kuroda S, Nojiri, Kido T, Senshu K, Nagai H, Koyanagi H, Sakai K, Akutsu T: In vitro evaluation of six different segmented polyurethanes and HEMA/st block copolymer using epifluorescent video microscopy. In Akutsu T, Koyanagi H (eds), Heart Replacement, Artificial Heart 5, pp.21-28, Springer-Verlag Tokyo, 1996
Kaneko Y, Sakai K, Yoshida R, Kikuchi A, Sakurai Y, Oakano T: Temperature responsive swelling and deswelling kinetics of poly (N isopropylacrylamide) grafted hydrogels. In Ogata N, Kim SW, Feijen J, Okano T (eds), Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems, pp.303-304,  Springer-Verlag Tokyo, 1995
Yoshida R, Kaneko Y, Sakai K, Okano T, Sakurai Y: Intelligent thermo-responsive hydrogels mechanism of on-off switches for drug release. In Aoki H (ed), Advanced Materials 1993: Biomaterials, Organic and Intelligent Materials, pp.659-662, Elsevier Science, 1994 
Sakai K: How chemical engineering helps to save lives - biomedical engineering. In Garside J, Furusaki S (eds), The Expanding World of Chemical Engineering, pp.99-110, Gordon and Breach Science Publishers, 1994
Yoshimi Y, Himi N, Sakai K: Development of a continuous method of immunoassay with an electrochemiluminescence flow cell for monitoring antibody level in body fluids. In Teo WK, Yap MGS, Oh SKW (eds), Better Living Through Innovative Biochemical Engineering, pp.723-725, National University of Singapore, 1994
Yoshimi Y, Himi N, Kanamori T, Sakai K: Development of noninvasive glucose sensor by electrogenerated chemiluminescence for clinical applications. In Furusaki S (ed), Biochemical Engineering for 2001, pp.629-632, Springer-Verlag, 1992
Okano T, Yoshida R, Sakai K, Sakurai Y: Thermo-responsive polymeric hydrogels and their application to pulsatile drug release. In DeRossi D, Kajiwara K, Osada Y, Yamauchi A (eds),   Polymer Gels, pp.299-308, Plenum Press, 1991
Ogasawara K, Kushiya F, Takeda T, Matsumoto T, Yoshida S,  Endo M, Horio T, Sakai K: Filtration characteristics of small-sized rotating filter for plasma separation. In Apheresis, pp. 379-381, Alan R Liss Inc, 1990
Mineshima M, Agishi T, Ota K, Sakai K: Performance of membrane filter for clinical use. In Proceedings of World Congress 2 of Chemical Engineering, pp.1065-1068, The Society of Chemical Engineers Japan, 1986
Ozawa K, Sakurai H, Takesawa S, Sakai K: Novel application of ceramic membranes to plasma separation. In Proceedings of World Congress 2 of Chemical Engineering, pp.1069-1072, The Society of Chemical Engineers Japan, 1986
Ozawa K, Kim HB, Sakurai H, Takesawa S, Sakai K: Novel utilization of ceramic membranes in plasma treatment. In Nose Y, Kjellstrand C, lvanovich P (eds), Progress in Artificial Organs 1985, pp. 913-920, ISAO Press, 1986
Horiuchi T, Malchesky PS, Matsugane T, Abe Y, Smith JW,  Sakai K, Nose Y: Effects of temperature and plasma constituents in plasma filtration. In Atsumi K, Maekawa M, Ota K (eds), Progress in Artificial Organs 1983, pp.691-697, ISAO Press, 1983

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