NothingMuch/GO-Terms huggingface dataset:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.
enteroendocrine cell differentiation
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.
aortic smooth muscle cell differentiation
The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.
aorta development
The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
ascending aorta development
The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
descending aorta development
The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
dorsal aorta development
The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.
ventral aorta development
The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
aorta morphogenesis
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
skeletal muscle cell differentiation
The regulated release of any steroid that acts as a hormone into the circulatory system.
steroid hormone secretion
The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism.
mineralocorticoid secretion
The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.
aldosterone secretion
The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.
glucocorticoid secretion
The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
corticosterone secretion
The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates.
androgen secretion
The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.
testosterone secretion
The selective degradation of protein aggregates by macroautophagy.
aggrephagy
The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein.
protein deglycosylation involved in glycoprotein catabolic process
The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.
tongue muscle cell differentiation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.
response to trichostatin A
The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.
tendon formation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length.
response to muscle stretch
Thin cylindrical membrane-covered projection on the surface of a rhabdomere.
rhabdomere microvillus
Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint.
imaginal disc-derived leg segmentation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis.
response to erythropoietin
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus.
cellular response to erythropoietin
An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place.
endolysosome
The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
mediator complex assembly
The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube.
cardiac neural crest cell delamination
The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
CD8-positive, alpha-beta T cell activation
The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide.
protein demalonylation
The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein.
protein desuccinylation
A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.
filtration diaphragm
The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.
filtration diaphragm assembly
The covalent attachment of a fucosyl group to an acceptor molecule.
fucosylation
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.
direct ossification
Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
purine nucleotide-sugar transmembrane transporter activity
The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.
germ cell proliferation
Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.
small molecule binding
A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT).
fatty acid beta-oxidation multienzyme complex
The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function.
Schwann cell migration
The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.
calcitonin secretion
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature.
filamentous growth of a population of unicellular organisms in response to heat
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
filamentous growth of a population of unicellular organisms in response to starvation
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.
filamentous growth of a population of unicellular organisms in response to chemical stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
response to neutral pH
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
filamentous growth of a population of unicellular organisms in response to pH
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.
filamentous growth of a population of unicellular organisms in response to neutral pH
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
filamentous growth of a population of unicellular organisms in response to biotic stimulus
The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).
zymosterol metabolic process
The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
granulocyte activation
The removal of glucuronic acid from a conjugated substrate.
deglucuronidation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.
response to methylamine
The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts.
RNA capping
The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.
RNA (guanine-N7)-methylation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.
response to antidepressant
The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.
atrioventricular canal development
The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.
lymph vessel morphogenesis
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.
response to sterol
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.
cellular response to sterol
Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity.
peptide pheromone receptor activity
The movement of a dendritic cell within or between different tissues and organs of the body.
dendritic cell migration
The lipid bilayer of a virion, a complete fully infectious extracellular virus particle.
viral membrane
Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
platelet morphogenesis
Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative.
racemase activity, acting on amino acids and derivatives
The controlled release of amylase from a cell of the pancreas.
pancreatic amylase secretion
Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs.
regulation of tRNA stability
Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.
citrate synthase activity
Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
2-dehydropantolactone reductase activity
A protein complex that has growth factor activity.
growth factor complex
The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon.
somatodendritic compartment
Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha.
regulation of translational initiation by eIF2 alpha dephosphorylation
Maintaining a protein in an unfolded, soluble state.
maintenance of unfolded protein
The series of molecular signals initiated by bile acid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
bile acid signaling pathway
The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.
specification of pronephric tubule identity
The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.
pronephric nephron morphogenesis
The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.
pronephric nephron tubule morphogenesis
The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
pronephric distal tubule morphogenesis
The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros.
pronephric nephron development
The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.
pronephric nephron tubule development
The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.
pronephric glomerulus development
The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.
pronephric duct development
Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts.
suppression by virus of host cell wall biogenesis
The breakdown of host DNA, deoxyribonucleic acid, by a virus.
catabolism by virus of host DNA
The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell.
host organelle outer membrane
The directed movement of the viral genome or a viral particle out of the host cell nucleus.
exit of virus from host cell nucleus
A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA.
rolling circle viral DNA replication
A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).
viral DNA strand displacement replication
The replication of a viral RNA genome.
viral RNA genome replication
A transcription process that uses viral RNA as a template.
RNA-templated viral transcription
A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template.
negative stranded viral RNA transcription
The assembly of a virus capsid that occurs in the cytoplasm.
cytoplasmic capsid assembly
A viral factory located in the cytoplasm of a host cell.
cytoplasmic viral factory
A viral factory located in the nucleus of a host cell.
nuclear viral factory
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
regulation of growth
Any process that modulates the rate of growth of all or part of an organism.
regulation of growth rate
Self-propelled movement of a cell or organism from one location to another.
locomotion
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
regulation of locomotion
The determination of sex and sexual phenotype in the germ line of a hermaphrodite.
hermaphrodite germ-line sex determination
The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
dauer larval development
The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
vulval development
Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
regulation of vulval development
The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA.
snRNA modification
The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.
hermaphrodite somatic sex determination
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host cell nucleus
The incorporation of a metal into a metallo-molybdopterin complex.
metal incorporation into metallo-molybdopterin complex
The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
fluid transport
The directed movement of fluid across epithelia.
epithelial fluid transport
The series of events that restore integrity to a damaged tissue, following an injury.
wound healing
Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
glial cell growth
The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
cell migration involved in gastrulation
Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.
5,10-methylenetetrahydrofolate-dependent methyltransferase activity
Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.
5-methyltetrahydrofolate-dependent methyltransferase activity
Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.
5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin.
5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity
The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
monocyte activation
The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
endothelial cell activation
The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
neutrophil activation
Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation.
glucanosyltransferase activity
The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.
meiotic DNA double-strand break formation