NothingMuch/GO-Terms huggingface dataset:
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.
membrane biogenesis
Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
negative regulation of molecular function
Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
positive regulation of molecular function
Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction.
host cell nuclear part
That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction.
host cell nucleoplasm
Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.
regulation of development of symbiont in host
A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
host cell junction
A prolongation or process extending from a host cell, e.g. a flagellum or axon.
host cell projection
A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
host thylakoid
The pigmented membrane of any host thylakoid.
host thylakoid membrane
A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.
host cell cytoplasmic vesicle
The lipid bilayer surrounding a host cell cytoplasmic vesicle.
host cell cytoplasmic vesicle membrane
A cellular structure that forms the internal framework of eukaryotic and prokaryotic host cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
host cytoskeleton
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
filamentous growth of a population of unicellular organisms
A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
host cell late endosome
A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions.
host cell lysosome
The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space.
host cell mitochondrial envelope
Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope.
host cell mitochondrial membrane
A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells.
cytolytic granule
The double lipid bilayer enclosing the host nucleus and separating its contents from the rest of the host cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
host cell nuclear envelope
Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space.
host cell nuclear membrane
The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.
host cell nuclear inner membrane
Any constituent part of a secondary organism with which the first organism is interacting.
other organism part
The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication.
host cell synapse
An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present.
host cell envelope
The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.
lipid digestion
Any of the smaller branches of an axon that emanate from the main axon cylinder.
axon collateral
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism.
cellular response to leptin stimulus
The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.
cell-cell adhesion mediated by cadherin
The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions.
sodium-dependent phosphate transport
The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised.
DNA excision
A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.
macropinosome
Binding to a small protein activating enzyme, such as ubiquitin-activating enzyme.
small protein activating enzyme binding
Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit.
ribosomal subunit
The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein.
protein targeting to vacuolar membrane
A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.
single-species biofilm formation in or on host organism
The modification of a protein amino acid by the addition of sulfur.
protein sulfhydration
Any process that modulates the quantity of fibrinogen circulating in the bloodstream.
regulation of circulating fibrinogen levels
The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall.
cellulosome assembly
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus.
response to amylopectin
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus.
response to pullulan
The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer.
daunorubicin metabolic process
The removal of a nucleotide from a protein amino acid.
protein denucleotidylation
Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).
ACP phosphopantetheine attachment site binding
The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.
adhesion of symbiont to host cell
The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).
sorocarp spore cell differentiation
A biological process that directly contributes to the process of producing new individuals, involving another organism.
multi-organism reproductive process
A multicellular organism process which involves another multicellular organism of the same or different species.
multi-multicellular organism process
Any process that modulates the size of an imaginal disc-derived wing.
regulation of imaginal disc-derived wing size
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
mitotic spindle pole body
The directed movement of proteins into an intracellular organelle, across a membrane.
protein transmembrane import into intracellular organelle
Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes.
amphisome
Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism.
ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.
mitotic cell cycle phase transition
The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities.
DNA polymerase III, core complex
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
bacterial-type flagellum organization
The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.
metaphase/anaphase transition of cell cycle
The DNA-dependent DNA replication that takes place as part of the cell cycle.
cell cycle DNA replication
A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected.
modulation by host of viral process
A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected.
negative regulation by host of viral process
A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected.
positive regulation by host of viral process
A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication.
DNA polymerase processivity factor complex
The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.
G-quadruplex DNA unwinding
A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.
mitotic G2/M transition checkpoint
The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle.
mitotic telomere tethering at nuclear periphery
The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle.
meiotic telomere tethering at nuclear periphery
Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.
retroviral integrase activity
Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism.
modulation by virus of host cytokine production
The cell cycle process by which a cell in G2 phase commits to M phase.
cell cycle G2/M phase transition
A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage.
gut granule
The cell cycle process by which a cell in G1 phase commits to S phase.
cell cycle G1/S phase transition
A distinct period or stage in a biological process or cycle.
biological phase
The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
hair cycle phase
A membrane raft that is part of the plasma membrane.
plasma membrane raft
The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft.
plasma membrane raft assembly
The process that establishes the spatial arrangement of membrane rafts within a plasma membrane.
plasma membrane raft distribution
Any process in which plasma membrane rafts are transported to, or maintained in, a specific location.
plasma membrane raft localization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.
plasma membrane raft organization
A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft.
protein localization to plasma membrane raft
The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.
modulation by host of viral exo-alpha-sialidase activity
The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected.
modulation by host of viral catalytic activity
A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected.
modulation by host of viral molecular function
A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process.
modulation by host of viral glycoprotein metabolic process
Any process in which a lipoprotein is transported to, or maintained in, a specific location.
lipoprotein localization
A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.
lipoprotein localization to membrane
Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats.
double-strand break repair via single-strand annealing
The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil.
DNA deamination
An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.
chitosome
The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.
G0 to G1 transition
The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.
transcytosis
Any process that modulates the frequency, rate or extent of viral genome replication.
regulation of viral genome replication
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
regulation of innate immune response
Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.
intermediate filament-based process
Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament.
intermediate filament polymerization or depolymerization
Disassembly of intermediate filaments by the removal of component monomers from a filament.
intermediate filament depolymerization
Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain.
intermediate filament polymerization
Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases.
regulation of intermediate filament polymerization or depolymerization
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
intermediate filament cytoskeleton
The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.
pronucleus
Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).
regulation of bone resorption
Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.
bioactive lipid receptor activity
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.
meiotic chromosome segregation
The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.
development of secondary sexual characteristics
The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.
development of primary sexual characteristics
Binding to a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.
myosin II binding
The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
neuronal ion channel clustering
The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate.
cell fate commitment
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
intercellular bridge
Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.
germline ring canal
The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.
basal part of cell
The region that lies just beneath the plasma membrane on the apical edge of a cell.
apical cortex
A translation regulator activity that does not involve binding to nucleic acids.
translation factor activity, non-nucleic acid binding
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
establishment or maintenance of epithelial cell apical/basal polarity
The specification and formation of the apicobasal polarity of an epithelial cell.
establishment of epithelial cell apical/basal polarity
A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
pyruvate dehydrogenase (lipoamide) phosphatase complex