NothingMuch/GO-Terms huggingface dataset:
The assembly of a virus capsid from its protein subunits.
viral capsid assembly
The encapsulation of the viral genome within the capsid.
viral genome packaging
The packing of viral DNA into a capsid.
viral DNA genome packaging
The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.
viral transcription
Binding to a pyrimidine nucleotide, a pyrimidine nucleoside esterified with (ortho)phosphate.
pyrimidine nucleotide binding
Catalysis of the transfer of a myristoyl (CH3-12-CO-) group to an acceptor molecule.
myristoyltransferase activity
Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene.
limonene monooxygenase activity
Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.
benzaldehyde dehydrogenase  activity
Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide.
hydroxy-nicotine oxidase activity
Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene.
phenanthrene-epoxide hydrolase activity
Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage.
hydrolase activity, acting on acid halide bonds, in C-halide compounds
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.
beta-1,4-mannosyltransferase activity
Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.
transmembrane receptor protein phosphatase activity
Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.
transmembrane receptor protein kinase activity
Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.
carbohydrate kinase activity
Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate.
amino acid kinase activity
Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate.
carbohydrate phosphatase activity
Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate.
nucleoside kinase activity
Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
kinase regulator activity
Binds to and modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
phosphatase regulator activity
Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
kinase activator activity
Binds to and stops, prevents or reduces the activity of a kinase.
kinase inhibitor activity
Binds to and increases the activity of a phosphatase.
phosphatase activator activity
Binds to and stops, prevents or reduces the activity of a phosphatase.
phosphatase inhibitor activity
Catalysis of the hydrolysis of an acetyl group from a substrate molecule.
deacetylase activity
Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.
intermediate filament binding
Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.
regulation of vasoconstriction
The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.
proprioception
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring.
cyclohydrolase activity
Catalysis of the removal of an amino group from a substrate, producing a substituted or nonsubstituted ammonia (NH3/NH2R).
deaminase activity
The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons.
ammonia oxidation
Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced.
fatty acid elongation, unsaturated fatty acid
The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
lipoxygenase pathway
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
fatty acid oxidation
The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.
peptidyl-proline hydroxylation
Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
toxin transmembrane transporter activity
The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+).
hydroxymate-containing siderophore biosynthetic process
The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. Catechol is one of the three major chemical groups incorporated into siderophore structures with hydroxamate and a-hydroxycarboxylate, each having a high selectivity for iron(3+).
catechol-containing siderophore biosynthetic process
The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene.
toluene oxidation
The pathways in which formaldehyde is processed and used as a carbon source for the cell.
formaldehyde assimilation
Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.
glycolytic fermentation
Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.
non-glycolytic fermentation
A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.
photosynthesis, dark reaction
The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.
purine nucleoside interconversion
The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside.
pyrimidine nucleoside interconversion
Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule.
protein-cysteine S-acyltransferase activity
Any process involved in the maintenance of an internal steady state at the level of the cell.
cellular homeostasis
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
antimicrobial humoral response
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.
antibacterial humoral response
An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.
antifungal humoral response
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.
nitrogen utilization
Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IgA receptor activity
Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IgE receptor activity
Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IgG receptor activity
The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.
proteasome core complex, alpha-subunit complex
The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.
proteasome core complex, beta-subunit complex
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.
procollagen-proline dioxygenase activity
Binding to a polyamine, an organic compound containing two or more amino groups.
polyamine binding
Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
isoprenoid binding
Binding to a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
vitamin binding
Binding to an immunoglobulin.
immunoglobulin binding
The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.
organelle inner membrane
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.
outer membrane
Binds to and stops, prevents, or reduces the activity of a potassium channel.
potassium channel inhibitor activity
Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.
protein kinase regulator activity
Binding to an enzyme, a protein with catalytic activity.
enzyme binding
Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.
kinase binding
Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
protein kinase binding
Binding to a phosphatase.
phosphatase binding
Binding to a protein phosphatase.
protein phosphatase binding
A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid).
sexual reproduction
Binding to a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
chemokine binding
Binding to a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
C-C chemokine binding
Binding to a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.
C-X-C chemokine binding
The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.
septate junction assembly
The plasma membrane surrounding a host cell.
host cell plasma membrane
A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation.
apical complex
The plastid organelle found in apicomplexans.
apicoplast
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
glycosome
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
kinetoplast
The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.
pellicle
The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.
neural fold bending
The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.
anterior neuropore closure
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
spinal cord development
The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.
spinal cord patterning
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.
ventral spinal cord interneuron differentiation
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
cell differentiation in spinal cord
The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.
dorsal spinal cord development
The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.
ventral spinal cord development
The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
spinal cord motor neuron cell fate specification
The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.
ventral spinal cord interneuron specification
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
spinal cord motor neuron differentiation
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
somatic motor neuron differentiation
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.
commissural neuron differentiation in spinal cord
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.
spinal cord oligodendrocyte cell differentiation
The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.
neural tube patterning
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
cell differentiation in hindbrain
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.
cell proliferation in hindbrain
The orderly movement of a cell that will reside in the hindbrain.
cell migration in hindbrain
The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
diencephalon development
The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.
epithalamus development
The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.
pallium development
The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.
subpallium development
The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
cranial nerve development
The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
rhombomere development
The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
pons development
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
cerebellum development
The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
central nervous system morphogenesis
The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
rhombomere 1 development
The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
rhombomere 2 development
The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
rhombomere 3 development
The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
rhombomere 4 development