NothingMuch/GO-Terms huggingface dataset:
The progression of the pulmonary valve over time, from its formation to the mature structure.
pulmonary valve development
The progression of the valve of the coronary sinus over time, from its formation to the mature structure.
coronary sinus valve development
The process in which the structure of the aortic valve is generated and organized.
aortic valve morphogenesis
The process in which the structure of the coronary sinus valve is generated and organized.
coronary sinus valve morphogenesis
The process in which the structure of the mitral valve is generated and organized.
mitral valve morphogenesis
The process in which the structure of the pulmonary valve is generated and organized.
pulmonary valve morphogenesis
The process in which the structure of the tricuspid valve is generated and organized.
tricuspid valve morphogenesis
The process in which the structure of the ventriculo bulbo valve is generated and organized.
ventriculo bulbo valve morphogenesis
The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
heart valve formation
The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
endocardial cushion development
A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.
epithelial to mesenchymal transition involved in endocardial cushion formation
The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
endocardial cushion morphogenesis
The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.
cardiac chamber development
The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
cardiac ventricle morphogenesis
The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
cardiac atrium morphogenesis
The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
cardiac atrium formation
The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
cardiac ventricle formation
The process in which the left cardiac atrium is generated and organized.
cardiac left atrium morphogenesis
The process in which the right cardiac atrium is generated and organized.
cardiac right atrium morphogenesis
The process in which the left cardiac ventricle is generated and organized.
cardiac left ventricle morphogenesis
The process in which the right cardiac ventricle is generated and organized.
cardiac right ventricle morphogenesis
The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.
ventricular compact myocardium morphogenesis
The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
cardiac atrium development
The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
cardiac ventricle development
The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.
bulbus arteriosus development
The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber.
bulbus arteriosus morphogenesis
The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.
sinus venosus development
The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.
sinus venosus morphogenesis
The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.
conus arteriosus development
The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.
conus arteriosus morphogenesis
Developmental growth that contributes to the shaping of the heart.
growth involved in heart morphogenesis
The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.
cardiac muscle tissue growth involved in heart morphogenesis
The multiplication or reproduction of cells that contributes to the shaping of a heart valve.
cell proliferation involved in heart valve morphogenesis
Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.
regulation of cell proliferation involved in heart valve morphogenesis
The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.
cardiac neural crest cell migration involved in outflow tract morphogenesis
Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.
regulation of membrane depolarization
The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
cardioblast migration
The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
cardioblast proliferation
Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
regulation of cardioblast proliferation
The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
endocardial cushion formation
The progression of the atrial septum over time, from its initial formation to the mature structure.
atrial septum development
The progression of the septum primum over time, from its formation to the mature structure.
septum primum development
The progression of the septum secundum over time, from its initial formation to the mature structure.
septum secundum development
The progression of the atrial septum intermedium over time, from its formation to the mature structure.
atrial septum intermedium development
The process in which an endocardial cushion cell becomes a cell of a cardiac septum.
cardiac septum cell differentiation
The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.
physiological muscle hypertrophy
The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis.
muscle hypertrophy in response to stress
The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.
cardiac muscle hypertrophy
The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.
physiological cardiac muscle hypertrophy
The orderly movement of a cell toward the midline that contributes to the progression of the heart over time.
cell migration to the midline involved in heart development
Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine.
positive regulation of blood pressure by epinephrine-norepinephrine
Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
regulation of extracellular matrix constituent secretion
The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure.
keratinocyte development
The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis.
corneocyte development
The process in which the anatomical structures of the metanephros are generated and organized.
metanephros morphogenesis
Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.
septum transversum development
The process in which the anatomical structure of the pericardium is generated and organized.
pericardium morphogenesis
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.
cardiac endothelial cell differentiation
The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.
brainstem development
The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.
noradrenergic neuron differentiation involved in brainstem development
Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell.
lamellipodium assembly involved in ameboidal cell migration
The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.
establishment of cell polarity involved in ameboidal cell migration
The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell.
cell-matrix adhesion involved in ameboidal cell migration
The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells.
cell-cell adhesion involved in ameboidal cell migration
The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell.
establishment of cell polarity involved in mesendodermal cell migration
Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.
establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration
The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.
establishment of cell polarity involved in gastrulation cell migration
Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.
establishment or maintenance of cytoskeleton polarity involved in gastrulation
The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.
epithelial cell morphogenesis involved in gastrulation
The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.
epithelial cell morphogenesis
The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.
apical constriction
The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.
apical constriction involved in gastrulation
The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.
amphid sensory organ development
The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland.
neuron differentiation involved in amphid sensory organ development
The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.
neuron development involved in amphid sensory organ development
The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.
retrograde extension
The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.
amphid sensory organ dendrite retrograde extension
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension.
cell adhesion involved in retrograde extension
The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension.
neuron migration involved in retrograde extension
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite.
cell adhesion involved in dendrite retrograde extension
The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite.
neuron migration involved in dendrite retrograde extension
The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.
cytoneme morphogenesis
The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.
optic vesicle morphogenesis
The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
neural retina development
The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
chondrocyte differentiation involved in endochondral bone morphogenesis
The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.
chondrocyte morphogenesis involved in endochondral bone morphogenesis
The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time.
chondrocyte hypertrophy
The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.
endochondral bone growth
The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.
growth plate cartilage development
The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
growth plate cartilage chondrocyte differentiation
The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.
growth plate cartilage chondrocyte proliferation
Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.
regulation of growth plate cartilage chondrocyte proliferation
The process in which the anatomical structures of growth plate cartilage are generated and organized.
growth plate cartilage morphogenesis
The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate.
growth plate cartilage chondrocyte division
A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.
cytoskeleton polarization involved in growth plate cartilage chondrocyte division
The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.
growth plate cartilage chondrocyte morphogenesis
The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.
growth plate cartilage chondrocyte development
The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.
chondrocyte development involved in endochondral bone morphogenesis
Binding to satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA.
satellite DNA binding
Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
translation release factor activity
Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.
DNA ligase activity
Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA.
DNA photolyase activity
Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
DNA topoisomerase activity
Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
GTP cyclohydrolase activity
Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.
cyclic-nucleotide phosphodiesterase activity
Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
dihydroorotate dehydrogenase activity
Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain.
aminopeptidase activity
Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain.
carboxypeptidase activity
Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
metallocarboxypeptidase activity
Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.
lactate dehydrogenase activity
Catalysis of the hydrolysis of ester linkages within nucleic acids.
nuclease activity
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
endonuclease activity
Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.
DNA exonuclease activity
Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.
chitinase activity
Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide.
dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
Catalysis of the hydrolysis of a glycerophospholipid.
phospholipase activity
Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).
prenyltransferase activity
cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
cyclic nucleotide-dependent protein kinase activity
Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA.
succinate-CoA ligase activity
Binds to and stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid.
phospholipase inhibitor activity
Binds to and stops, prevents or reduces the activity of a protein kinase.
protein kinase inhibitor activity
Combining with a mating-type factor pheromone to initiate a change in cell activity.
mating-type factor pheromone receptor activity
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
chemokine receptor activity
Combining with the neurotransmitter dopamine to initiate a change in cell activity.
dopamine neurotransmitter receptor activity