NothingMuch/GO-Terms huggingface dataset:
Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
regulation of cardioblast differentiation
The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
membrane depolarization
Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
regulation of mitochondrial depolarization
Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
regulation of fibrinolysis
Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.
regulation of sensory perception of pain
Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
regulation of sensory perception
The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
catecholamine transport
Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of amine transport
Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of amino acid transport
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
regulation of nervous system development
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
regulation of synaptic transmission, glutamatergic
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.
lysophospholipid transport
Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.
copper chelate transmembrane transporter activity
Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
regulation of chromosome segregation
Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule.
Se-methyltransferase activity
The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
positive energy taxis
The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
negative energy taxis
A type of cell wall modification in which the cell wall is reinforced and made thicker.
cell wall thickening
Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol.
inositol phosphosphingolipid phospholipase activity
Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol.
inositol phosphorylceramide phospholipase activity
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.
oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor
Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate.
inositol tetrakisphosphate phosphatase activity
Catalysis of the reaction: phosphatidyl-1D-myo-inositol monophosphate + H2O = phosphatidylinositol + phosphate.
phosphatidylinositol monophosphate phosphatase activity
Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate.
inositol phosphate phosphatase activity
The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.
amino disaccharide metabolic process
The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.
chitobiose metabolic process
The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.
amino disaccharide catabolic process
The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.
reuteran metabolic process
Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate.
inositol pentakisphosphate phosphatase activity
Catalysis of the reaction: diphospho-1D-myo-inositol tetrakisphosphate + H2O = 1D-myo-inositol pentakisphosphate + phosphate.
inositol diphosphate tetrakisphosphate diphosphatase activity
Catalysis of the reaction: bisdiphospho-1D-myo-inositol tetrakisphosphate + H2O = diphospho-1D-myo-inositol pentakisphosphate + phosphate.
inositol bisdiphosphate tetrakisphosphate diphosphatase activity
Catalysis of the reaction: diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate.
inositol diphosphate pentakisphosphate diphosphatase activity
Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor.
oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein.
oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein.
oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin.
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.
striated muscle cell development
Any process that modulates the frequency, rate or extent of cardiac muscle growth.
regulation of cardiac muscle tissue growth
Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol.
cortical microtubule
A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity.
nuclear DNA-directed RNA polymerase complex
The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.
Bolwig's organ development
The lipid bilayer membrane of any thylakoid within a plastid.
plastid thylakoid membrane
The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata.
symplast
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins.
anastral spindle assembly
Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other.
D-glucose transmembrane transporter activity
The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
asymmetric neuroblast division
Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell.
chloride ion homeostasis
Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.
potassium ion homeostasis
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
sodium ion homeostasis
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
lipid homeostasis
Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
sterol homeostasis
Binds to and stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.
lipase inhibitor activity
Binds to and modulates the activity of a ligase.
ligase regulator activity
Binds to and stops, prevents or reduces the activity of a ubiquitin-protein transferase.
ubiquitin-protein transferase inhibitor activity
Binds to and modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.
ubiquitin-protein transferase regulator activity
The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
epiboly involved in gastrulation with mouth forming second
The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.
entry into diapause
The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
entry into reproductive diapause
Any process that modulates the frequency, rate or extent of cardiac muscle contraction.
regulation of cardiac muscle contraction
Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.
negative regulation of cardiac muscle contraction
The process in which the extent of cardiac muscle contraction is reduced.
relaxation of cardiac muscle
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
response to very low light intensity stimulus
The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
digestive system development
An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.
reflex
A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.
vestibular reflex
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
Sertoli cell differentiation
The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.
Sertoli cell development
The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.
granulosa cell differentiation
The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.
parathyroid gland development
The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.
astrocyte fate commitment
The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
radial glial cell differentiation
Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.
rhythmic synaptic transmission
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.
convergent extension
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
convergent extension involved in gastrulation
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.
convergent extension involved in axis elongation
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.
convergent extension involved in organogenesis
The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.
notochord cell differentiation
The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
notochord cell development
The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the structure it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
pharyngeal system development
The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.
pericardium development
The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.
retinal bipolar neuron differentiation
Any process that modulates the frequency, rate or extent of the acrosome reaction.
regulation of acrosome reaction
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.
angiogenesis involved in wound healing
The tissue remodeling that removes differentiated mammary epithelia during weaning.
mammary gland involution
A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.
excitatory synapse
A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
inhibitory synapse
The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.
membrane hyperpolarization
A compound molecular function in which an effector function is controlled by one or more regulatory components.
molecular transducer activity
A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia.
kinocilium
Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
regulation of synaptic transmission, glycinergic
Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
regulation of phagocytosis, engulfment
Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
positive regulation of phagocytosis, engulfment
Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
negative regulation of phagocytosis, engulfment
The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans.
cortical layer of collagen and cuticulin-based cuticle extracellular matrix
Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.
regulation of growth hormone secretion
A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.
maternal process involved in female pregnancy
A reproductive process occurring in the mother that results in birth.
maternal process involved in parturition
Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
regulation of syncytium formation by plasma membrane fusion
Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
positive regulation of syncytium formation by plasma membrane fusion
The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron.
regulation of timing of neuron differentiation
The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
astral microtubule depolymerization
Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
regulation of aggregation involved in sorocarp development
The specific behavior of a male organism that is associated with reproduction.
male mating behavior
The specific behavior of a female organism that is associated with reproduction.
female mating behavior
The process in which a cell switches cell cycle mode.
cell cycle switching
Either of two different areas at opposite ends of an axis of a cell.
cell pole
Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
regulation of protein desumoylation