NothingMuch/GO-Terms huggingface dataset:
The action of a molecule that contributes to the structural integrity of a postsynapse.
structural constituent of postsynapse
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.
presynaptic cytoskeleton organization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.
postsynaptic cytoskeleton organization
The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic component of synaptic membrane
Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.
vesicle fusion to plasma membrane
The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.
calcium-dependent activation of synaptic vesicle fusion
A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
secretory vesicle
A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.
synaptic vesicle cycle
Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.
voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels
A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.
polymeric cytoskeletal fiber
The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors.
synaptic vesicle cytoskeletal transport
The transport of organelles or other particles from one location in the cell to another along actin filaments.
actin filament-based transport
The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors.
synaptic vesicle transport along microtubule
The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.
presynaptic dense core vesicle exocytosis
Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel).
neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
Any process that increases the concentration of calcium ions in the presynaptic cytosol.
positive regulation of presynaptic cytosolic calcium concentration
Cell-cell signaling to, from or within a synapse.
synaptic signaling
Cell-cell signaling in either direction across the synaptic cleft.
trans-synaptic signaling
Cell-cell signaling to or from a synapse, mediated by a peptide.
synaptic signaling via neuropeptide
Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft.
trans-synaptic signaling by neuropeptide
Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.
trans-synaptic signaling by lipid
Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand.
trans-synaptic signaling by endocannabinoid
Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft.
trans-synaptic signaling by soluble gas
Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.
trans-synaptic signaling by trans-synaptic complex
Any process that modulates synaptic transmission by regulating translation occurring at the synapse.
regulation of translation at synapse, modulating synaptic transmission
Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide.
trans-synaptic signaling by nitric oxide
Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.
trans-synaptic signaling by carbon monoxide
Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse.
trans-synaptic signaling, modulating synaptic transmission
Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.
trans-synaptic signaling by neuropeptide, modulating synaptic transmission
Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse.
trans-synaptic signaling by lipid, modulating synaptic transmission
Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.
trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse.
trans-synaptic signaling by soluble gas, modulating synaptic transmission
Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.
trans-synaptic signaling by nitric oxide, modulating synaptic transmission
Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.
cytoplasmic region
The portion of the cytoskeleton contained within the presynapse.
presynaptic cytoskeleton
The portion of the cytoskeleton contained within the postsynapse.
postsynaptic cytoskeleton
A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
postsynaptic specialization
Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
serotonin receptor activity
A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor.
neurotransmitter receptor internalization
Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors.
regulation of neurotransmitter receptor activity
A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.
neurotransmitter receptor regulator activity
Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
ligand-gated calcium channel activity
The cellular process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).
lateral attachment of mitotic spindle microtubules to kinetochore
A process in which a protein is transported to or maintained in a location within an axon.
protein localization to axon
The side (leaflet) of the mitochondrial inner membrane that faces the matrix.
matrix side of mitochondrial inner membrane
The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
cardiac muscle cell membrane repolarization
The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
atrial cardiac muscle cell membrane repolarization
The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
ventricular cardiac muscle cell membrane repolarization
The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping).
neurotransmitter receptor cycle
The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane.
neurotransmitter receptor diffusion trapping
A process in which protein is transported from one region of the plasma membrane to another.
protein transport within plasma membrane
The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
postsynaptic specialization membrane
The directed movement of neurotransmitter receptors.
neurotransmitter receptor transport
The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.
endosome to plasma membrane protein transport
The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.
neurotransmitter receptor transport, endosome to plasma membrane
Any signal release from a synapse.
signal release from synapse
Any action potential process that regulates skeletal muscle contraction.
regulation of skeletal muscle contraction by action potential
Any prostaglandin biosynthetic process process that regulates fever generation.
regulation of fever generation by prostaglandin biosynthetic process
Any prostaglandin secretion process that regulates fever generation.
regulation of fever generation by prostaglandin secretion
The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population.
vascular endothelial cell proliferation
The process in which a nuclear membrane is synthesized, aggregates, and bonds together.
nuclear membrane biogenesis
The regrowth of axons of the optical nerve following their loss or damage.
optical nerve axon regeneration
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.
cellular response to environmental stimulus
Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.
intestinal hexose absorption
Any process that regulates the localization of a protein to the medial cortex.
regulation of protein localization to medial cortex
Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex.
positive regulation of protein localization to medial cortex
Any process that modulates the frequency, rate or extent of the inflammatory response to wounding.
regulation of inflammatory response to wounding
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
phosphatidylinositol-3,4-bisphosphate phosphatase activity
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
phosphatidylinositol-3,5-bisphosphate phosphatase activity
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.
phosphatidylinositol-4,5-bisphosphate phosphatase activity
Any process that modulates the onset of pupariation.
regulation of pupariation
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite.
neuron projection organization
The collection of neuronal projections into a bundle of rods, known as a fascicle.
neuron projection fasciculation
The removal of a sugar or dicarbonyl from a glycated guanine.
guanine deglycation
The modification of acetylpolyamine by the removal of acetyl groups.
polyamine deacetylation
Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress.
regulation of cellular response to osmotic stress
Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling.
regulation of calcineurin-mediated signaling
Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signaling.
negative regulation of calcineurin-mediated signaling
Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling.
positive regulation of calcineurin-mediated signaling
Any process that modulates the frequency, rate or extent of exit from mitosis.
regulation of exit from meiosis
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
regulation of cobalamin metabolic process
Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide.
peptide N-succinyltransferase activity
Any protein complex that is part of the nuclear membrane.
nuclear membrane protein complex
Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.
regulation of cell adhesion involved in sprouting angiogenesis
The process of creating an elongation or projection from a glial cell.
glial cell projection elongation
A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules.
nuclear membrane microtubule tethering complex
Any process that modulates the frequency, rate or extent of glutamate receptor clustering.
regulation of glutamate receptor clustering
Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
regulation of (R)-mevalonic acid biosynthetic process
Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
regulation of mitotic cohesin ssDNA (lagging strand) loading
Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.
regulation of mitotic cohesin dsDNA (leading strand) loading
Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.
regulation of sterol biosynthetic process
Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process.
negative regulation of sterol biosynthetic process
Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process.
positive regulation of sterol biosynthetic process
A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes.
reservosome
Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.
purine phosphoribosyltransferase activity
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction.
positive regulation of cardiac muscle cell contraction
Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction.
negative regulation of cardiac muscle cell contraction
Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.
regulation of vesicle fusion with Golgi apparatus
Catalysis of the reaction: glutaryl-CoA + L-lysyl- = CoA + H+ + N6-glutaryl-L-lysyl-.
peptide glutaryltransferase activity
Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.
regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA
The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.
resolvin biosynthetic process
Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H.
glyoxylate reductase activity
Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.
snRNA methyltransferase activity
The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.
snRNA methylation
The set of processes involved in identifying and degrading defective or aberrant tRNAs.
tRNA surveillance
Catalysis of the reaction: a 2-hydroxy fatty acyl-CoA = a fatty aldehyde + formyl-CoA. The reaction acts on 2-hydroxy-3-methyl-branched fatty acyl-CoA and 2-hydroxy-long-chain fatty acyl-CoA.
2-hydroxyacyl-CoA lyase activity
Any process which produces a purine ribonucleotide from derivatives of it, without de novo synthesis.
purine ribonucleotide salvage
Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis.
purine deoxyribonucleotide salvage
Any process that modulates the frequency, rate or extent of a palmitic acid catabolic process.
regulation of palmitic acid catabolic process
Any process that modulates the frequency, rate or extent of R7 cell fate commitment.
regulation of R7 cell fate commitment
Catalysis of the reaction: RNA-uracil + NAD(P)+ = RNA-dihydrouridine + NAD(P)H + H+.
RNA dihydrouridine synthase activity
Any process that modulates the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.
regulation of kainate selective glutamate receptor signaling pathway
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation.
regulation of tRNA methylation
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation.
regulation of tRNA C5-cytosine methylation
Any process that activates or increases the frequency, rate or extent of tRNA methylation.
positive regulation of tRNA methylation
A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.
formin-nucleated actin cable organization
Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.
regulation of basement membrane organization
The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.
cap-independent translational initiation of linear mRNA
Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.
regulation of actomyosin structure organization
The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
cardiac muscle myoblast proliferation
Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.
regulation of cardiac muscle myoblast proliferation
The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing.
DNA strand resection involved in replication fork processing
Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing.
regulation of DNA strand resection involved in replication fork processing
Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.
positive regulation of mitotic spindle organization
Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
negative regulation of meiosis I
Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
regulation of G2/MI transition of meiotic cell cycle
Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
negative regulation of G2/MI transition of meiotic cell cycle
Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized.
regulation of nematode male tail tip morphogenesis
The process in which the anatomical structures of the nematode pharynx are generated and organized.
nematode pharynx morphogenesis
Any process that modulates the frequency, rate or extent of nematode pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.
regulation of nematode pharynx morphogenesis
A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.
metabolite repair
Any process that modulates the frequency, rate or extent of actin filament organization.
regulation of actin filament organization
Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
regulation of actin filament annealing