NothingMuch/GO-Terms huggingface dataset:
A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.
cytosolic proteasome regulatory particle
The core complex of a proteasome located in the nucleus of a cell.
nuclear proteasome core complex
The core complex of a proteasome located in the cytosol of a cell.
cytosolic proteasome core complex
A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
receptor internalization
Binding to an opioid receptor.
opioid receptor binding
Binding to replication fork barriers, sites that inhibit the progress of replication forks.
replication fork barrier binding
Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
regulation of myelination
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
regulation of protein stability
Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.
heat generation
Any process that modulates the rate or extent of heat generation.
regulation of heat generation
Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.
heat dissipation
Any process that modulates the rate or extent of heat dissipation.
regulation of heat dissipation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
response to nutrient levels
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
cellular response to nutrient levels
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
cellular response to nutrient
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.
primary cell septum biogenesis
The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
chromoplast envelope
The lipid bilayer surrounding an early endosome.
early endosome membrane
The lipid bilayer surrounding a late endosome.
late endosome membrane
The lipid bilayer surrounding a microbody.
microbody membrane
The volume enclosed by the membrane of an endosome.
endosome lumen
The volume enclosed by the membrane of a late endosome.
late endosome lumen
The volume enclosed by the membranes of a microbody.
microbody lumen
Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems.
oral apparatus
A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.
regulation of synaptic metaplasticity
The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
vitamin B6 transport
The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
pyridoxal transport
The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
pyridoxamine transport
The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
pyridoxine transport
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
regulation of glucocorticoid biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.
regulation of glucocorticoid catabolic process
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
nuclear membrane
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
mitochondrial membrane
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
organelle envelope
The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.
organelle outer membrane
Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
chloroplast membrane
The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
membrane-enclosed lumen
Any thylakoid within a plastid.
plastid thylakoid
The volume enclosed by a thylakoid membrane.
thylakoid lumen
The volume enclosed by a plastid thylakoid membrane.
plastid thylakoid lumen
The volume enclosed by the nuclear inner membrane.
nuclear lumen
The volume enclosed by the membrane or protein that forms a vesicle.
vesicle lumen
Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation.
regulation of fatty acid beta-oxidation
The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.
signal transduction involved in positive regulation of conjugation with cellular fusion
An intracellular signaling cassette in which a small monomeric GTPase of the ARF subfamily relays a signal.
ARF protein signal transduction
Any process that modulates the frequency, rate or extent of ARF protein signal transduction.
regulation of ARF protein signal transduction
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion (Co2+) stimulus.
response to cobalt ion
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
response to magnesium ion
Binding to a light chain of a myosin complex.
myosin light chain binding
Binding to the head/neck region of a myosin heavy chain.
myosin head/neck binding
Binding to the tail region of a myosin heavy chain.
myosin tail binding
Binding to a heavy chain of a myosin complex.
myosin heavy chain binding
Binding to a heavy chain of a myosin I complex.
myosin I heavy chain binding
Binding to a heavy chain of a myosin II complex.
myosin II heavy chain binding
Binding to a bile acid, a steroid carboxylic acids occurring in bile.
bile acid binding
Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.
regulation of restriction endodeoxyribonuclease activity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
response to food
Any process that modulates the frequency, rate or extent of a response to a food stimulus.
regulation of response to food
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
regulation of response to external stimulus
Any process that modulates the frequency, rate or extent of a response to nutrient levels.
regulation of response to nutrient levels
Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate.
regulation of carbohydrate phosphatase activity
A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization.
eisosome
Binding to an alkylated residue in DNA.
alkylated DNA binding
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
cleavage furrow
The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes.
septin cytoskeleton
A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.
septin band
A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
septin cap
Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis.
cleavage apparatus septin structure
A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well.
split septin rings
The slender tubular outgrowth first produced by most spores in germination.
germ tube
Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. For elements that are transcribed as the first step of transposition, the process starts with the transcription of the transposable element, its translation and maturation, and ending with integration into DNA. For elements that are cut out, the process starts with the excision of the donor DNA and integrated into another site.
transposition
Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
regulation of telomere maintenance
Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.
regulation of telomere maintenance via recombination
Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.
regulation of telomere maintenance via telomerase
Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
regulation of telomere maintenance via semi-conservative replication
Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
regulation of synaptic transmission, cholinergic
Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
regulation of synaptic transmission, dopaminergic
Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
regulation of synaptic transmission, GABAergic
The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
adenosine transport
Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of nucleoside transport
Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of purine nucleoside transport
Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of adenosine transport
A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.
cytoplasm to vacuole targeting by the Cvt pathway
The process in which a methyl group is covalently attached to a molecule.
methylation
Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.
purine nucleotide salvage
Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.
pyrimidine nucleotide salvage
The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.
luteinizing hormone secretion
Any complex formed of proteins that act in mismatch repair.
mismatch repair complex
The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
molybdopterin cofactor catabolic process
The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
alanine transport
Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
regulation of chondrocyte differentiation
The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.
activin secretion
The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.
inhibin secretion
Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.
regulation of activin secretion
Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.
regulation of inhibin secretion
The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
aldosterone biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
regulation of aldosterone biosynthetic process
The directed movement of lipids within cells.
intracellular lipid transport
The directed movement of sterols within cells.
intracellular sterol transport
The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.
intracellular cholesterol transport
Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of lipid transport
Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of sterol transport
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of cholesterol transport
Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.
regulation of intracellular lipid transport
Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.
regulation of intracellular sterol transport
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.
regulation of intracellular cholesterol transport
Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
regulation of intracellular transport
The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
DNA geometric change
Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.
inhibitory MHC class I receptor activity
Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
activating MHC class I receptor activity
The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
melanosome transport
Binding to a mismatch repair complex.
mismatch repair complex binding
Any process that modulates the activity of a transporter.
regulation of transporter activity
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
stereocilium
Any process that modulates the frequency, rate or extent of mismatch repair.
regulation of mismatch repair
Any process that modulates the activity of the enzyme phospholipase A2.
regulation of phospholipase A2 activity
Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
regulation of proteasomal ubiquitin-dependent protein catabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.
regulation of ergosterol biosynthetic process
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.
protein modification by small protein conjugation
Catalysis of the removal of a methyl group from a substrate.
demethylase activity
Catalysis of the removal of a methyl group from a histone.
histone demethylase activity
Any process that modulates the frequency, rate or extent of protein oligomerization.
regulation of protein oligomerization
Any process that modulates the frequency, rate or extent of protein homooligomerization.
regulation of protein homooligomerization
The process in which the anatomical structures of an otolith are generated and organized.
otolith morphogenesis
The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.
otolith formation
An intracellular signaling cassette in which a small monomeric GTPase of the Rab subfamily relays a signal.
Rab protein signal transduction
An intracellular signaling cassette in which a small monomeric GTPase of the RaI subfamily relays a signal.
Ral protein signal transduction
An intracellular signaling cassette in which a small monomeric GTPase of the Rap subfamily relays a signal.
Rap protein signal transduction
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.
response to bacterial lipoprotein
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
response to peptidoglycan
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.
response to muramyl dipeptide
The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.
detection of peptidoglycan
A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).
cytokinetic process
A process that modulates the length of a microvillus.
regulation of microvillus length
A process that modulates the size of a cellular component.
regulation of cellular component size