NothingMuch/GO-Terms huggingface dataset:
A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed.
Bcl-2 family protein complex
The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.
GABAergic neuron differentiation
Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.
organic cyclic compound binding
The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.
lens epithelial cell proliferation
Binding to a mitochondrial ribosome.
mitochondrial ribosome binding
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.
response to azide
A renal system process in which fluid circulating through the body is filtered through a barrier system.
renal filtration
A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.
alveolar lamellar body
A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.
epidermal lamellar body
A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas.
sieve plate
The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
sperm midpiece
The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
lamellar body membrane
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
cellular response to toxic substance
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
cellular response to methylglyoxal
Binding to a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge.
flavonoid binding
The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.
renal tubular secretion
Cell killing caused by the membrane attack complex formed following complement activation.
complement-dependent cytotoxicity
Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.
histamine secretion mediated by immunoglobulin
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
cellular response to alcohol
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
response to farnesol
A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.
bacterial biofilm matrix
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.
response to N-acetyl-D-glucosamine
The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.
ripoptosome assembly
A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair.
INO80-type complex
The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added.
prenylation
The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.
chorionic trophoblast cell proliferation
Binding to a carbohydrate derivative.
carbohydrate derivative binding
The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.
sensory neuron axon guidance
The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.
interneuron axon guidance
The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.
spinal cord interneuron axon guidance
Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
photoreceptor disc membrane
The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.
neuroblast migration
The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
protein maturation by iron-sulfur cluster transfer
The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.
maintenance of dormancy
The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state.
acquisition of desiccation tolerance
A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.
apical dendrite
The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches.
dendritic tree
An axon of a hippocampal granule cell, including dentate gyrus granule cell and CA3 granule cell, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.
hippocampal mossy fiber
Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
cyclin-dependent protein kinase activity
The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
motor neuron migration
The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.
spinal cord motor neuron migration
The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme.
lateral motor column neuron migration
Long distance growth of a single dendrite involved in cellular development.
dendrite extension
A membrane-bounded vesicle wholly contained within a multivesicular body.
multivesicular body, internal vesicle
The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling.
structural molecule activity conferring elasticity
Any process that modulates the size of a vesicle.
regulation of vesicle size
A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel.
blood vessel lumen ensheathment
The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet.
blood vessel endothelial cell delamination
Any endothelial tube morphogenesis process by which the tube is increased in length.
endothelial tube lumen extension
The covalent attachment of a mannose residue to a substrate molecule.
mannosylation
The covalent attachment of sialic acid to a substrate molecule.
sialylation
An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.
contractile actin filament bundle
An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.
parallel actin filament bundle
A plasma membrane that is part of a sperm cell.
sperm plasma membrane
A small ribonucleoprotein complex involved in formation of the spliceosome.
spliceosomal snRNP complex
A spliceosomal snRNP complex that is formed by the association of the U4/U6 (or U4atac/U6atac) snRNP with the U5 snRNP.
spliceosomal tri-snRNP complex
The movement of a myeloid leukocyte within or between different tissues and organs of the body.
myeloid leukocyte migration
The movement of a granulocyte within or between different tissues and organs of the body.
granulocyte migration
The movement of a mast cell within or between different tissues and organs of the body.
mast cell migration
The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells.
lateral part of cell
The region directly beneath the plasma membrane of the lateral portion of the cell.
lateral cell cortex
Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.
vacuole fusion
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.
lamellipodium organization
Cell motility due to movement of bacterial- or archaeal-type flagella.
archaeal or bacterial-type flagellum-dependent cell motility
The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm.
cytoplasmic translational elongation through polyproline stretches
The orderly movement of a distal tip cell.
distal tip cell migration
Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.
calcitonin family receptor activity
Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).
calcitonin family binding
Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects.
response to pulsatile fluid shear stress
Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis.
response to oscillatory fluid shear stress
Any response to pulsatile fluid shear stress that occurs at the level of a cell.
cellular response to pulsatile fluid shear stress
Any response to oscillatory fluid shear stress that occurs at the level of a cell.
cellular response to oscillatory fluid shear stress
Any vesicle that is part of the intracellular region.
intracellular vesicle
The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared.
connective tissue replacement
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.
response to viscosity
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.
RNA polymerase activity
A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules).
membrane tubulation
A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae).
icosahedral viral capsid, neck
A small disk located at the base of some icosahedral virus capsids.
icosahedral viral capsid, collar
The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase.
viral DNA genome packaging via site-specific sequence recognition
The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
sensory perception of high humidity
The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
sensory perception of low humidity
The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity.
detection of humidity stimulus involved in sensory perception
The series of events in which a humidity stimulus is received and converted into a molecular signal.
detection of humidity
The series of events in which high humidity is detected and converted into a molecular signal.
detection of high humidity
The series of events in which low humidity is detected and converted into a molecular signal.
detection of low humidity
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction.
excitatory neuromuscular junction
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction.
inhibitory neuromuscular junction
A neuromuscular junction in which the target muscle cell is a myotube.
neuromuscular junction of myotube
A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell.
neuromuscular junction of somatic muscle myotube
A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods.
neuromuscular junction of somatic muscle
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.
skeletal muscle fiber differentiation
A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.
ATPase dependent transmembrane transport complex
A cellular process that results in the assembly of one or more centrioles.
centriole assembly
Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.
maintenance of protein complex location
A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface.
side of membrane
The side (leaflet) of the plasma membrane that faces the lumen.
lumenal side of endoplasmic reticulum membrane
The side (leaflet) of the plasma membrane that faces the cytoplasm.
cytoplasmic side of endoplasmic reticulum membrane
The side of a membrane that faces the cytoplasm.
cytoplasmic side of membrane
The volume enclosed within the membrane of a transport vesicle.
transport vesicle lumen
The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface.
periplasmic side of plasma membrane
The side (leaflet) of the mycolate outer membrane that faces the environment and any proteins embedded in it or loosely bound to its surface.
external side of mycolate outer membrane
The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.
stromal side of plastid inner membrane
The side (leaflet) of the plastid thylakoid membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.
stromal side of plastid thylakoid membrane
Any side (leaflet) of a membrane that faces the lumen of an organelle.
lumenal side of membrane
A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
host cell synaptic vesicle
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
cellular response to virus
The lipid bilayer that forms the outer-most layer of an organelle.
bounding membrane of organelle
Learning in which new behaviors are acquired through imitation.
imitative learning
Learning that occurs through observing the behavior of others.
observational learning
Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned.
learned vocalization behavior or vocal learning
Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.
palmitoyl hydrolase activity
Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.
protein complex involved in cell-cell adhesion
Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion.
protein complex involved in cell-matrix adhesion
A collagen trimer that forms networks.
network-forming collagen trimer
A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands).
banded collagen fibril
A supramolecular complex that consists of collagen triple helices associated to form a network.
collagen network
A specialised collagen fibril that functions as an anchor, binding to other collagen structures.
collagen anchoring fibril
Any collagen timer that is part of a basement membrane.
basement membrane collagen trimer
An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis.
collagen type VII anchoring fibril
Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.
regulation of synaptic vesicle cycle
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
postsynaptic specialization assembly
Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.
asymmetric stem cell division
Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population.
symmetric stem cell division
Cell division in which both daughter cells are of the same type.
symmetric cell division
Any process by which the numbers of cells of a particular type or in a tissue are maintained.
maintenance of cell number
The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.
germline stem cell asymmetric division