NothingMuch/GO-Terms huggingface dataset:
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
collagen-containing extracellular matrix
Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
regulation of stress granule assembly
Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.
positive regulation of mitotic sister chromatid segregation
The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.
sensory perception of cold stimulus
The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.
sensory perception of hot stimulus
A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells.
biofilm matrix
Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
regulation of cardiac epithelial to mesenchymal transition
Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
positive regulation of cardiac epithelial to mesenchymal transition
Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
negative regulation of cardiac epithelial to mesenchymal transition
Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte.
inhibitory MHC class Ib receptor activity
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.
regulation of capsule polysaccharide biosynthetic process
Any process that modulates the frequency, rate or extent of vein smooth muscle contraction.
regulation of vein smooth muscle contraction
Any process that modulates the rate, frequency or extent of taurine biosynthesis.
regulation of taurine biosynthetic process
The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.
stomach development
Any process that modulates the frequency, rate or extent of programmed necrotic cell death.
regulation of programmed necrotic cell death
Any process that decreases the frequency, rate or extent of programmed necrotic cell death.
negative regulation of programmed necrotic cell death
Any process that increases the frequency, rate or extent of programmed necrotic cell death.
positive regulation of programmed necrotic cell death
Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.
RNA 2'-O-methyltransferase activity
Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip.
regulation of protein localization to non-growing cell tip
Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components.
regulation of DNA recombinase disassembly
The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle.
zinc ion import into organelle
Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
regulation of mitochondrial gene expression
Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis.
regulation of L-glutamine biosynthetic process
Any protein complex that is part of a membrane and which functions as a cargo receptor.
cargo receptor complex
The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.
detection of stimulus involved in sensory perception of pain
The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection.
pseudohyphal septin ring assembly
Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly.
regulation of pseudohyphal septin ring assembly
Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding.
regulation of plus-end directed microtubule sliding
Catalysis of the hydroxylation of C-23 of any form of vitamin D.
vitamin D 23-hydroxylase activity
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress.
cellular response to chemical stress
Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.
regulation of pattern recognition receptor signaling pathway
Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.
positive regulation of pattern recognition receptor signaling pathway
Any process that regulates the rate, frequency or extent of somatic muscle development.
regulation of somatic muscle development
Any process that increases the rate, frequency or extent of somatic muscle development.
positive regulation of somatic muscle development
Any process that decreases the rate, frequency or extent of somatic muscle development.
negative regulation of somatic muscle development
Any process that modulates the rate, frequency or extent of adult somatic muscle development.
regulation of adult somatic muscle development
Any process that modulates the rate, frequency or extent of larval somatic muscle development.
regulation of larval somatic muscle development
The chemical reactions and pathways resulting in the breakdown of prostanoids.
prostanoid catabolic process
Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.
protein localization to postsynapse
The pattern specification process in which the polarity of a body or organ axis is established and maintained.
specification of axis polarity
The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.
protein-lipid complex assembly
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
aspartic-type peptidase activity
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.
glutamic-type peptidase activity
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
threonine-type peptidase activity
Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
cysteine-type exopeptidase activity
Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
serine-type exopeptidase activity
An organelle lumen that is part of an intracellular organelle.
intracellular organelle lumen
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.
rRNA (pseudouridine) methyltransferase activity
Binding to an RNA polymerase molecule or complex.
RNA polymerase binding
A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
cytochrome complex
The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.
proton-transporting two-sector ATPase complex assembly
The covalent attachment and further modification of carbohydrate residues to a substrate molecule.
glycosylation
The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).
glucagon secretion
Any process that modulates the frequency, rate or extent of the regulated release of glucagon.
regulation of glucagon secretion
The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.
tRNA aminoacylation for mitochondrial protein translation
Evagination of a membrane to form a synaptic vesicle.
synaptic vesicle budding
The regulated release of adiponectin, a protein hormone, by adipose tissue.
adiponectin secretion
Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.
regulation of adiponectin secretion
Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
regulation of biomineral tissue development
Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
negative regulation of biomineral tissue development
Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
positive regulation of biomineral tissue development
Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
regulation of tooth mineralization
Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
negative regulation of tooth mineralization
Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
positive regulation of tooth mineralization
Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
regulation of enamel mineralization
The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.
contractile vacuole discharge
The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
actin-mediated cell contraction
The regulated release of somatostatin from secretory granules in the D cells of the pancreas.
somatostatin secretion
Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.
tyrosyl-DNA phosphodiesterase activity
A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).
cornification
Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate.
vitamin B6 binding
The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.
sarcoplasmic reticulum calcium ion transport
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
cellular response to hydrogen peroxide
A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.
regulation of G0 to G1 transition
Binding to a lipoprotein particle receptor.
lipoprotein particle receptor binding
Binding to a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.
flap-structured DNA binding
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.
response to bacterial lipopeptide
The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.
detection of bacterial lipopeptide
Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.
galactose-1-phosphate phosphatase activity
The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.
prolactin secretion
The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.
rRNA base methylation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
response to oxygen levels
Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
oligosaccharide binding
Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.
death domain binding
Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid.
L-tryptophan aminotransferase activity
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
protein K63-linked deubiquitination
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
response to fatty acid
Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid.
L-glutamine aminotransferase activity
Catalysis of the transfer of an adenylyl group to an acceptor.
adenylyltransferase activity
Catalysis of the transfer of a cytidylyl group to an acceptor.
cytidylyltransferase activity
Catalysis of the transfer of a guanylyl group to an acceptor.
guanylyltransferase activity
Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
regulation of neuron projection regeneration
Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
positive regulation of neuron projection regeneration
The attachment of one cell to another cell affecting gastrulation.
cell-cell adhesion involved in gastrulation
Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.
regulation of cell-cell adhesion involved in gastrulation
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.
spore wall biogenesis
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.
ascospore wall biogenesis
The directed movement of a substance from one side of an epithelium to the other.
transepithelial transport
A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.
protein modification by small protein removal
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
protein modification by small protein conjugation or removal
Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.
actin filament bundle distribution
The regrowth of a sensory epithelium following its loss or destruction.
sensory epithelium regeneration
The regrowth of lost or destroyed mechanosensory epithelia.
mechanosensory epithelium regeneration
Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.
mechanoreceptor differentiation involved in mechanosensory epithelium regeneration
The regrowth of a neuromast following its loss or destruction.
neuromast regeneration
The regrowth of lost or destroyed inner ear sensory epithelia.
inner ear sensory epithelium regeneration
The expansion of a leukocyte population by cell division.
leukocyte proliferation
The expansion of a mast cell population by cell division.
mast cell proliferation
Any process that modulates the frequency, rate or extent of leukocyte proliferation.
regulation of leukocyte proliferation
Any process that modulates the frequency, rate or extent of mast cell proliferation.
regulation of mast cell proliferation
Binding to a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.
transmembrane receptor protein serine/threonine kinase binding
Binding to an activin receptor.
activin receptor binding
Catalysis of the introduction of a double bond into a sterol molecule.
sterol desaturase activity
The modification of an RNA molecule by insertion of one or more nucleotides.
RNA nucleotide insertion
The modification of an RNA molecule by insertion of a dinucleotide.
RNA dinucleotide insertion
Binding to a stretch of purines (adenine or guanine) in an RNA molecule.
poly-purine tract binding
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
response to cholesterol
The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.
cell wall assembly
The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.
cyclic nucleotide transport
The process in which D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid  is transported across a lipid bilayer, from one side of a membrane to the other, by means of some agent such as a transporter or pore.
D-aspartate transmembrane transport
A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.
growth of unicellular organism as a thread of attached cells
Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
regulation of growth of unicellular organism as a thread of attached cells
Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
negative regulation of growth of unicellular organism as a thread of attached cells
Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
positive regulation of growth of unicellular organism as a thread of attached cells
The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
conidiophore development
The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
conidiophore stalk development
The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
cleistothecium development
Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
regulation of conidiophore development