NothingMuch/GO-Terms huggingface dataset:
The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.
GG-NER
GGR
global genome NER
global genomic nucleotide-excision repair
global genomic repair
Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.
LPA receptor activity
A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).
IPC synthase complex
Binds to and modulates the activity of inositol phosphoceramide synthase.
IPC synthase regulator activity
The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing complement complex that mediates gene silencing by small RNA.
gene silencing by RNA, small RNA loading onto RISC
miRISC assembly
miRNA loading onto RISC
RISC assembly
siRNA loading onto RISC involved in gene silencing by small RNA
siRNA loading onto RISC involved in RNA interference
small RNA loading onto RISC
A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.
co-translational protein tagging
cotranslational protein tagging
protein modification by trans-translation
An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).
coding region determinant-mediated mRNA stabilization
A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.
coding-region determinant of instability-mediated mRNA stability complex
coding-region instability determinant -mediated mRNA stability complex
A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.
CATCHR family complex
Dsl1p complex
NZR complex
Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.
down regulation of neutrophil mediated killing of gram-negative bacterium
down-regulation of neutrophil mediated killing of gram-negative bacterium
downregulation of neutrophil mediated killing of gram-negative bacterium
inhibition of neutrophil mediated killing of gram-negative bacterium
Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.
down regulation of neutrophil mediated killing of gram-positive bacterium
down-regulation of neutrophil mediated killing of gram-positive bacterium
downregulation of neutrophil mediated killing of gram-positive bacterium
inhibition of neutrophil mediated killing of gram-positive bacterium
Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.
down regulation of neutrophil mediated killing of fungus
down-regulation of neutrophil mediated killing of fungus
downregulation of neutrophil mediated killing of fungus
inhibition of neutrophil mediated killing of fungus
Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.
activation of neutrophil mediated killing of gram-negative bacterium
stimulation of neutrophil mediated killing of gram-negative bacterium
up regulation of neutrophil mediated killing of gram-negative bacterium
up-regulation of neutrophil mediated killing of gram-negative bacterium
upregulation of neutrophil mediated killing of gram-negative bacterium
Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.
activation of neutrophil mediated killing of gram-positive bacterium
stimulation of neutrophil mediated killing of gram-positive bacterium
up regulation of neutrophil mediated killing of gram-positive bacterium
up-regulation of neutrophil mediated killing of gram-positive bacterium
upregulation of neutrophil mediated killing of gram-positive bacterium
Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.
activation of neutrophil mediated killing of fungus
stimulation of neutrophil mediated killing of fungus
up regulation of neutrophil mediated killing of fungus
up-regulation of neutrophil mediated killing of fungus
upregulation of neutrophil mediated killing of fungus
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
no-go decay
no-go mRNA decay
nuclear-transcribed mRNA breakdown, no-go decay
nuclear-transcribed mRNA catabolism, no-go decay
nuclear-transcribed mRNA degradation, no-go decay
Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.
PQQ binding
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
ER exit site
transitional ER
A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.
protein localisation to endoplasmic reticulum exit site
protein localization to ER exit site
Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.
Forkhead-associated domain binding
Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.
Toll-Interleukin receptor domain binding
The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
biphenyl breakdown
biphenyl catabolism
biphenyl degradation
The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.
L-asparagine anabolism
L-asparagine biosynthesis
L-asparagine formation
L-asparagine synthesis
Binding to a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.
SET binding
A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.
cyclin H-CDK7 complex
Mcs6/Mcs2/Pmh1 complex
TFIIK complex
The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).
left-right axis specification
left/right axis determination
Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized  = a medium-chain trans-(2E)-enoyl-CoA + reduced . A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
MCAD activity
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.
NADP (reduced) dehydrogenation
NADP (reduced) oxidation
NADPH dehydrogenation
reduced NADP dehydrogenation
reduced NADP oxidation
reduced nicotinamide adenine dinucleotide phosphate dehydrogenation
reduced nicotinamide adenine dinucleotide phosphate oxidation
Binding to a type 1 melanocortin receptor.
type 1 melanocortin receptor ligand
A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.
penta-RNP complex
A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.
GT-AG prespliceosome
major prespliceosome
mammalian U2-type spliceosomal complex A
yeast U2-type spliceosomal complex B
A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.
GT-AG precatalytic spliceosome
major precatalytic spliceosome
mammalian U2-type spliceosomal complex B
mammalian U2-type spliceosomal complex B1
yeast U12-type spliceosomal complex A2-1
A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.
GT-AG catalytic step 1 spliceosome
major catalytic step 1 spliceosome
mammalian U2-type spliceosomal complex B*
mammalian U2-type spliceosomal complex B2
U2-type activated spliceosome
yeast U2-type spliceosomal complex A1
A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.
GT-AG catalytic step 2 spliceosome
major catalytic step 2 spliceosome
mammalian U2-type spliceosomal complex C
mammalian U2-type spliceosomal complex C1
yeast U2-type spliceosomal complex A2-2
A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.
GT-AG post-mRNA release spliceosomal complex
major post-mRNA release spliceosomal complex
mammalian U2-type spliceosomal complex I
U2/U5/U6 snRNP complex
U2/U5/U6 tri-snRNP complex
A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs.
U4atac/U6atac.U5 snRNP complex
A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.
AT-AC prespliceosome
mammalian U12-type spliceosomal complex A
minor prespliceosome
yeast U12-type spliceosomal complex B
A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.
AT-AC precatalytic spliceosome
mammalian U12-type spliceosomal complex B
mammalian U12-type spliceosomal complex B1
minor precatalytic spliceosome
yeast U12-type spliceosomal complex A2-1
A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.
AT-AC catalytic step 1 spliceosome
mammalian U12-type spliceosomal complex B*
mammalian U12-type spliceosomal complex B2
minor catalytic step 1 spliceosome
U12-type activated spliceosome
yeast U12-type spliceosomal complex A1
A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.
AT-AC catalytic step 2 spliceosome
mammalian U12-type spliceosomal complex C
mammalian U12-type spliceosomal complex C1
minor catalytic step 2 spliceosome
yeast U12-type spliceosomal complex A2-2
A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.
AT-AC post-mRNA release spliceosomal complex
mammalian U12-type spliceosomal complex I
minor post-mRNA release spliceosomal complex
A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.
GT-AG post-spliceosomal complex
major post-spliceosomal complex
mammalian U2-type spliceosomal complex C2
yeast U2-type spliceosomal complex A2-3
A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.
AT-AC post-spliceosomal complex
mammalian U12-type spliceosomal complex C2
minor post-spliceosomal complex
yeast U12-type spliceosomal complex A2-3
The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.
nuclear mRNA quality control of incorrectly spliced pre-mRNA
nuclear RNA catabolic process of incorrectly spliced pre-mRNA
The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.
nuclear mRNA catabolic process of mRNA with aberrant 3\'-ends
nuclear mRNA quality control of mRNAs with aberrant 3\'-ends
The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.
nuclear mRNA catabolic process of mRNAs in aberrant mRNPs
nuclear mRNA quality control of mRNAs in aberrant mRNPs
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.
nuclear poly(A)-dependent rRNA catabolic process
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.
nuclear poly(A)-dependent snoRNA catabolic process
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.
nuclear poly(A)-dependent snRNA catabolic process
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.
nuclear poly(A)-dependent CUT catabolic process
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.
nuclear poly(A)-dependent antisense transcript catabolic process
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.
nuclear poly(A)-dependent mRNA catabolic process
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.
nuclear poly(A)-dependent ncRNA catabolic process
Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.
polyadenylation-dependent snoRNA 3\'-end processing
sno(s)RNA polyadenylation
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.
ITGA9-ITGB1-ADAM1 complex
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.
ITGA9-ITGB1-ADAM2 complex
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.
ITGA9-ITGB1-ADAM3 complex
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.
ITGA9-ITGB1-ADAM9 complex
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.
ITGA9-ITGB1-ADAM15 complex
A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.
ITGAV-ITGB3-ADAM15 complex
A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151.
ITGA3-ITGB1-CD151 complex
A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.
ITGA6-ITGB1-CD151 complex
A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151.
ITGA7-ITGB1-CD151 complex
A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.
ITGA6-ITGB4-CD151 complex
A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin.
ITGAV-ITGB3-VTN complex
A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.
ITGAE-ITGB7-CDH1 complex
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.
ITGA9-ITGB1-VCAM1 complex
The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.
detection of mechanical stimulus involved in sensory perception of air flow
detection of wind
perception of wind, detection of mechanical stimulus
perception of wind, sensory detection of mechanical stimulus
perception of wind, sensory transduction of mechanical stimulus
sensory detection of mechanical stimulus during perception of wind
sensory transduction of mechanical stimulus during perception of wind
sensory transduction of wind
A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.
ITGAV-ITGB3-ADAM23 complex
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.
ITGA9-ITGB1-ADAM12 complex
A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1.
ITGA4-ITGB1-THBS1 complex
A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2.
ITGA4-ITGB1-THBS2 complex
Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other.
adenosine 3\',5\'-diphosphate transporter activity
adenosine 3\'-phosphate-5\'-phosphate transmembrane transporter activity
A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.
FN-TGM2 complex
A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.
ITGA2-ITGB1-CHAD complex
A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.
ITGA3-ITGB1-BSG complex
A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63.
ITGA3-ITGB1-CD63 complex
A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.
ITGA9-ITGB1-TNC complex
A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).
ITGAV-ITGB3-CD447-FCER2 complex
A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.
ITGA2-ITGB1-CD47 complex
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.
ITGA2b-ITGB3-CD9 complex
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.
ITGA2b-ITGB3-CD9-GP1b-CD47 complex
A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen.
ITGA11-ITGB1-COL1A1 complex
A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.
ITGA5-ITGB1-TGM2 complex
A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.
ITGAV-ITGB3-TGM2 complex
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.
ITGA2b-ITGB3-FN1-TGM2 complex
A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.
ITGA1-ITGB1-TGM2 complex
A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.
ITGA3-ITGB1-TGM2 complex
A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.
ITGA5-ITGB1-FN1-TGM2 complex
A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.
ITGA6-ITGB4-CD9 complex
A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin.
ITGA3-ITGB1-THBS1 complex
A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin.
ITGAV-ITGB3-Gsn complex
A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.
ITGAV-ITGB3-PXN-PTK2b complex
A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.
ITGA6-ITGB4-FYN complex
A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).
ITGAV-ITGB6-TFGB3 complex
A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).
ITGAV-ITGB8-MMP14-TGFB1 complex
A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.
ITGA4-ITGB1-JAM2 complex
A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin.
ITGA4-ITGB1-PXN complex