NothingMuch/GO-Terms huggingface dataset:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
adaptive response to oxidative stress
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
cellular response to heat stress
The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
turning behavior during mating
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
response to TNF
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
cellular response to active oxygen species
cellular response to AOS
cellular response to reactive oxidative species
cellular response to reactive oxygen intermediate
cellular response to ROI
cellular response to ROS
Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.
BH4 binding
H4biopterin binding
sapropterin binding
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
heat shock protein activity
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
de novo NAD biosynthetic process
Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
attachment of spindle microtubules to SPB
attachment of spindle microtubules to spindle pole body
microtubule anchoring at SPB
The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
phosphatidylcholine breakdown
phosphatidylcholine catabolism
phosphatidylcholine degradation
Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.
L-amino acid efflux permease activity
L-amino acid export transporter activity
The directed movement of the mitochondrion to a specific location, by a process involving microtubules.
establishment of mitochondrion localisation, microtubule-mediated
microtubule-mediated mitochondrion localization
mitochondrial localization, microtubule-mediated
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
cellular response to ultraviolet light stimulus
cellular response to ultraviolet radiation stimulus
cellular response to UV light stimulus
cellular response to UV radiation stimulus
The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
cortisol metabolism
The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
cortisol anabolism
cortisol biosynthesis
cortisol formation
cortisol synthesis
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
nucleobase, nucleoside, nucleotide and nucleic acid anabolism
nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis
nucleobase, nucleoside, nucleotide and nucleic acid formation
nucleobase, nucleoside, nucleotide and nucleic acid synthesis
The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.
nucleobase, nucleoside, nucleotide and nucleic acid breakdown
nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
nucleobase, nucleoside, nucleotide and nucleic acid catabolism
nucleobase, nucleoside, nucleotide and nucleic acid degradation
The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
nucleobase, nucleoside and nucleotide breakdown
nucleobase, nucleoside and nucleotide catabolism
nucleobase, nucleoside and nucleotide degradation
The directed movement of a motile cell or organism in response to the presence of arachidonic acid.
chemotaxis to arachidonic acid
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.
response to prostaglandin stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
response to prostaglandin E stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.
response to prostaglandin F stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.
response to prostaglandin I stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.
response to gonadotropin stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.
response to luteinizing hormone stimulus
A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.
SMN-containing protein complex
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.
nucleosome organisation
A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.
AhR complex
AHRC
A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
ferrous ion transmembrane transport
ferrous iron transmembrane transport
high affinity ferrous ion transmembrane transport
high affinity iron ion transport
high-affinity ferrous ion transmembrane transport
high-affinity iron ion transmembrane transport
high-affinity iron ion transport
iron ion membrane transport
iron(2+) transmembrane transport
low affinity iron ion transport
low-affinity iron ion transmembrane transport
low-affinity iron ion transport
transmembrane iron transport
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of Fe transport
regulation of iron import
regulation of iron ion import
regulation of iron transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of iron ion transport
down-regulation of iron ion transport
downregulation of iron ion transport
inhibition of iron ion transport
negative regulation of iron transport
Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
activation of iron ion transport
positive regulation of iron transport
stimulation of iron ion transport
up regulation of iron ion transport
up-regulation of iron ion transport
upregulation of iron ion transport
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.
regulation of iron ion membrane transport
regulation of transmembrane Fe transport
regulation of transmembrane iron ion transport
regulation of transmembrane iron transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
down regulation of transmembrane iron ion transport
down-regulation of transmembrane iron ion transport
downregulation of transmembrane iron ion transport
inhibition of transmembrane iron ion transport
negative regulation of iron ion membrane transport
negative regulation of transmembrane iron ion transport
negative regulation of transmembrane iron transport
Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
activation of transmembrane iron ion transport
positive regulation of iron ion membrane transport
positive regulation of transmembrane iron ion transport
positive regulation of transmembrane iron transport
stimulation of transmembrane iron ion transport
up regulation of transmembrane iron ion transport
up-regulation of transmembrane iron ion transport
upregulation of transmembrane iron ion transport
Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
regulation of membrane transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
down regulation of transmembrane transport
down-regulation of transmembrane transport
downregulation of transmembrane transport
inhibition of transmembrane transport
negative regulation of membrane transport
Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
activation of transmembrane transport
positive regulation of membrane transport
stimulation of transmembrane transport
up regulation of transmembrane transport
up-regulation of transmembrane transport
upregulation of transmembrane transport
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
regulation of ion membrane transport
regulation of ion transmembrane transport
regulation of transmembrane ion transport
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
down regulation of transmembrane ion transport
down-regulation of transmembrane ion transport
downregulation of transmembrane ion transport
inhibition of transmembrane ion transport
negative regulation of ion membrane transport
negative regulation of ion transmembrane transport
negative regulation of transmembrane ion transport
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
activation of transmembrane ion transport
positive regulation of ion membrane transport
positive regulation of ion transmembrane transport
positive regulation of transmembrane ion transport
stimulation of transmembrane ion transport
up regulation of transmembrane ion transport
up-regulation of transmembrane ion transport
upregulation of transmembrane ion transport
The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.
basal lamina disassembly
A process in which glutathione is transported across a membrane.
glutathione membrane transport
transmembrane glutathione transport
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
response to histamine stimulus
Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA.
box C/D snoRNA processing
box C/D sRNA processing
Any process involved in the conversion of a primary box H/ACA type small RNA transcript into a mature box H/ACA RNA.
box H/ACA snoRNA processing
box H/ACA sRNA processing
A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).
oxidative protein folding
protein folding in ER
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
cellular response to endoplasmic reticulum stress
ER stress response
response to ER stress
Catalysis of the reaction: N(6)-acetyl-L-lysyl- + NAD+ + H2O = L-lysyl- + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group from a protein to NAD, producing nicotinamide.
NAD(+)-dependent protein deacetylase
NAD(+)-dependent protein deacylase
NAD-dependent protein deacetylase activity
protein acetyllysine N-acetyltransferase
protein lysine deacetylase
protein lysine deacylase
The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import.
mitochondrial protein modification
Binding to one or more specific sites on an immunoglobulin receptor molecule.
Fc receptor binding
A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.
MAS
microtubule organising centre attachment site
MTOC attachment site
A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis.
LINC complex
LInker of Nucleoskeleton and Cytoskeleton complex
SUN-KASH complex
The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
melanization defence response
Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.
regulation of melanization defence response
Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.
down regulation of melanization defense response
down-regulation of melanization defense response
downregulation of melanization defense response
inhibition of melanization defense response
negative regulation of melanization defence response
Modulates the activity of a phosphatidylinositol 3-kinase (PI3K). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.
phosphoinositide 3-kinase regulator activity
PI3K regulator activity
A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).
class III PI3K complex
phosphoinositide 3-kinase complex, class III
The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.
male pronucleus formation
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
cardiac cell differentiation
heart cell differentiation
The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
larval midgut regression
The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.
puparium biosynthesis
puparium formation
A nuclear receptor-mediated signaling pathway initiated by an ecdysone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.
ecdysone receptor-mediated signalling pathway
nuclear receptor-mediated ecdysone signaling pathway
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
axoneme biogenesis
ciliary axoneme assembly
cilium axoneme assembly
cilium axoneme biogenesis
flagellar axoneme assembly
flagellum axoneme assembly
Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
phosphoinositide binding
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
limb bud morphogenesis
The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.
genital morphogenesis
The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
embryonic unpaired fin morphogenesis
The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.
post-embryonic genital morphogenesis
The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
post-embryonic unpaired fin morphogenesis
The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
arm morphogenesis
The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
median fin morphogenesis
unpaired fin morphogenesis
A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
EJC
exon junction complex
Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.
lumen formation in an anatomical structure
tube lumen formation
Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.
regulation of tracheal tube size
Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.
regulation of tracheal tube architecture
Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.
tracheal cell type specification
tracheal epithelial cell type specification
The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.
terminal cell fate specification
The stages of blood cell formation that take place within the embryo.
embryonic haematopoiesis
embryonic haemopoiesis
embryonic hematopoiesis
The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
embryonic arthropod blood cell differentiation
embryonic hemocyte cell differentiation
The stages of blood cell formation that take place after completion of embryonic development.
post-embryonic haemopoiesis
The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
larval lymph gland haematopoiesis
larval lymph gland haemopoiesis
larval lymph gland hematopoiesis