NothingMuch/GO-Terms huggingface dataset:
Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.
activation of acetylcholine secretion
stimulation of acetylcholine secretion
up regulation of acetylcholine secretion
up-regulation of acetylcholine secretion
upregulation of acetylcholine secretion
Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.
regulation of adrenaline secretion
Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.
regulation of noradrenaline secretion
Any process that modulates the frequency, rate or extent of the regulated release of serotonin.
regulation of serotonin release
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
neuronal postsynaptic density
post synaptic density
post-synaptic density
postsynaptic density of dendrite
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
response to organic cyclic substance
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.
response to purine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
response to amine stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
response to selective serotonin reuptake inhibitor
response to SSRI
A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.
intercalated disk
Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction.
regulation of skeletal muscle contraction by calcium ion signalling
Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres.
regulation of the velocity of shortening of skeletal muscle during contraction
Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
regulation of skeletal muscle plasticity
Any process that activates or increases the frequency, rate or extent of muscle adaptation.
positive regulation of muscle plasticity
Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.
negative regulation of muscle plasticity
Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
smooth muscle plasticity
The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
release of sequestered calcium ion by sarcoplasmic reticulum into cytosol
The series of events by which an injury stimulus is received and converted into a molecular signal.
detection of injury
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
response to exercise
A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion.
vascular smooth muscle contraction
The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool.
satellite cell asymmetric division
Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells.
satellite cell compartment self-renewal involved in skeletal muscle regeneration
satellite cell population maintenance
satellite cell self-renewal
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation.
response to fatigue
response to muscle activity involved in regulation of muscle plasticity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.
response to stimulus involved in regulation of muscle plasticity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.
response to injury involved in regulation of muscle plasticity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.
response to electrical stimulus involved in regulation of muscle plasticity
The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
cardiac muscle plasticity
Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
striated muscle plasticity
The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.
regulation of pulmonary blood pressure
The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.
corrin metabolism
The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase.
coenzyme F430 metabolic process
nickel-tetrapyrrole coenzyme metabolism
The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
heparan sulfate proteoglycan anabolism
heparan sulfate proteoglycan biosynthesis
heparan sulfate proteoglycan formation
heparan sulfate proteoglycan synthesis
heparan sulphate proteoglycan biosynthesis
heparan sulphate proteoglycan biosynthetic process
heparin proteoglycan biosynthetic process
Catalysis of the reaction: glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H+ + UDP.
1-naphthol glucuronyltransferase activity
1-naphthol-UDP-glucuronosyltransferase activity
17-beta-hydroxysteroid UDP-glucuronosyltransferase activity
17-OH steroid UDPGT activity
17beta-hydroxysteroid UDP-glucuronosyltransferase activity
3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity
3-OH androgenic UDPGT activity
3alpha-hydroxysteroid UDP-glucuronosyltransferase activity
4-hydroxybiphenyl UDP-glucuronosyltransferase activity
4-methylumbelliferone UDP-glucuronosyltransferase activity
4-nitrophenol UDP-glucuronyltransferase activity
4-nitrophenol UDPGT activity
bilirubin glucuronyltransferase activity
bilirubin monoglucuronide glucuronyltransferase activity
bilirubin UDP-glucuronosyltransferase activity
bilirubin UDPGT activity
bilirubin uridine diphosphoglucuronyltransferase activity
ciramadol UDP-glucuronyltransferase activity
estriol UDPglucuronosyltransferase activity
estrone UDPglucuronosyltransferase activity
GT activity
morphine glucuronyltransferase activity
p-hydroxybiphenyl UDP glucuronyltransferase activity
p-nitrophenol UDP-glucuronosyltransferase activity
p-nitrophenol UDP-glucuronyltransferase activity
p-nitrophenylglucuronosyltransferase activity
p-phenylphenol glucuronyltransferase activity
phenyl-UDP-glucuronosyltransferase activity
PNP-UDPGT
pnp-UDPGT activity
UDP glucuronate-estradiol-glucuronosyltransferase activity
UDP glucuronate-estriol glucuronosyltransferase activity
UDP glucuronic acid transferase activity
UDP glucuronosyltransferase activity
UDP glucuronyltransferase activity
UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)
UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity
UDP-glucuronate-bilirubin glucuronyltransferase activity
UDP-glucuronosyltransferase activity
UDP-glucuronyltransferase activity
UDPGA transferase activity
UDPGA-glucuronyltransferase activity
UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity
UDPGT activity
uridine 5\'-diphosphoglucuronyltransferase activity
uridine diphosphate glucuronyltransferase activity
uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity
uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity
uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity
uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity
uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity
uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity
uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity
uridine diphosphoglucuronate-estriol glucuronosyltransferase activity
uridine diphosphoglucuronosyltransferase activity
uridine diphosphoglucuronyltransferase activity
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
coiled body
Gemini of coiled bodies
Gems
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
enzyme transport
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
haem lyase disulphide oxidoreductase activity
heme lyase disulfide oxidoreductase activity
peptide disulfide oxidoreductase activity
peptide disulphide oxidoreductase activity
protein disulfide oxidoreductase activity
protein disulfide-oxidoreductase activity
protein disulphide oxidoreductase activity
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
disulphide oxidoreductase activity
Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
glutaredoxin
glutathione disulphide oxidoreductase activity
glutathione oxidoreductase activity
Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.
dinucleotide phosphate reductase activity
NAD(P)--rubredoxin oxidoreductase activity
NAD(P)H--rubredoxin oxidoreductase activity
NADPH:rubredoxin reductase activity
rubredoxin--nicotinamide adenine activity
rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity
rubredoxin:NAD(P)+ oxidoreductase activity
Catalysis of the reversible transfer of an amidino group to an acceptor.
transamidinase activity
Enables the transfer of an ion from one side of a membrane to the other.
ion transmembrane transporter activity
ion transporter activity
Enables the transfer of a proton from one side of a membrane to the other.
hydrogen ion transmembrane transporter activity
proton transporter activity
Enables the transfer of potassium ions (K+) from one side of a membrane to the other.
potassium transporter activity
potassium uptake permease activity
potassium uptake transmembrane transporter activity
Enables the transfer of silver (Ag+) ions from one side of a membrane to the other.
silver transporter activity
Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.
sodium transporter activity
Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.
zinc, cadmium uptake permease activity
zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity
Enables the transfer of cobalt (Co2+) ions from one side of a membrane to the other.
cobalt, zinc uptake permease activity
zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity
Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
ferrous iron uptake transmembrane transporter activity
Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid.
molybdate transporter activity
Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.
zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity
Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
hydrogencarbonate transmembrane transporter activity
Enables the transfer of chloride ions from one side of a membrane to the other.
ATP-dependent chloride transmembrane transporter activity
ATPase-coupled chloride transmembrane transporter activity
chloride ABC transporter
chloride ion transmembrane transporter activity
chloride transporting ATPase activity
chloride-transporting ATPase activity
Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other.
nitrite/nitrate porter activity
Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other.
nitrite/nitrate porter activity
Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
sulfate permease activity
sulphate transporter activity
Enables the transfer of thiosulfate ions, HS2O3(1-), from one side of a membrane to the other.
thiosulfate permease activity
thiosulphate transporter activity
Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity
Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other.
tricarboxylate transport protein
Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
dicarboxylate (succinate/fumarate/malate) antiporter activity
Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.
2-oxoglutarate transporter activity
Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
dicarboxylate (succinate/fumarate/malate) antiporter activity
Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other.
dicarboxylate (succinate/fumarate/malate) antiporter activity
Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.
sodium:dicarboxylate/tricarboxylate symporter activity
Enables the transfer of carbohydrate from one side of a membrane to the other.
carbohydrate transporter activity
sugar transporter
Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.
L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity
Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.
ATP-dependent rhamnose transmembrane transporter activity
ATPase-coupled rhamnose transmembrane transporter activity
rhamnose-transporting ATPase activity
Enables the transfer of lactose from one side of a membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.
lactose permease activity
lactose/glucose efflux transporter activity
Enables the transfer of oligosaccharide from one side of a membrane to the other.
endosomal oligosaccharide transporter
Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.
raffinose permease
Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.
glucuronide transporter activity
Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol.
sugar/polyol channel activity
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
amino acid permease activity
amino acid transporter activity
amino acid/choline transmembrane transporter activity
general amino acid permease activity
hydroxy/aromatic amino acid permease activity
Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.
acidic amino acid transporter activity
Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring.
aromatic amino acid transporter activity
hydroxy/aromatic amino acid permease activity
valine/tyrosine/tryptophan permease activity
Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3.
basic amino acid permease activity
basic amino acid transporter activity
cationic amino acid transmembrane transporter activity
Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3.
neutral amino acid transmembrane transporter activity
neutral amino acid transporter activity
Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.
L-amino acid transporter activity
Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.
L-alanine transporter activity
Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid.
asparagine/glutamine permease activity
L-asparagine transporter activity
Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.
glutamate/aspartate porter activity
glutamate/aspartate:sodium symporter activity
L-aspartate transporter activity
Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).
4-aminobutanoate transporter activity
4-aminobutyrate transporter activity
betaine/GABA:sodium symporter activity
GABA transporter activity
Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.
asparagine/glutamine permease activity
Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.
glycine betaine/proline porter activity
glycine transporter activity
proline/glycine/betaine:hydrogen/sodium symporter activity