NothingMuch/GO-Terms huggingface dataset:
The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
Moco metabolic process
Moco metabolism
W-molybdopterin cofactor metabolism
The behavior of an organism in response to an odor.
behavioral response to scent
behavioral response to smell
behavioural response to odour
behavioural response to scent
behavioural response to smell
olfactory behaviour
The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.
adult eye photoreceptor development
The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.
rhabdomere organization
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
regulation of dopamine metabolism
Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or a lysine residue.
histone methylase activity
histone N-methyltransferase activity
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.
attractant
Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
regulation of EGF receptor signaling pathway
regulation of EGF receptor signalling pathway
regulation of EGFR signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
down regulation of epidermal growth factor receptor signaling pathway
down-regulation of epidermal growth factor receptor signaling pathway
downregulation of epidermal growth factor receptor signaling pathway
inhibition of epidermal growth factor receptor signaling pathway
negative regulation of EGF receptor signaling pathway
negative regulation of EGF receptor signalling pathway
negative regulation of EGFR signaling pathway
The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.
glial cell generation  systematic_synonym
The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
establishment of ommatidial polarity
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine.
regulation of pteridine metabolism
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.
regulation of catecholamine metabolism
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
IFT
intraflagellar transport
intraflagellar transport involved in cilium organization
intraflagellar transport involved in microtubule-based flagellum organisation
The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.
phosphoglycosylation
protein amino acid phosphate-linked glycosylation
The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.
germ-line stem cell renewal
An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.
Th1 immune response
An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
T-helper 2 type immune response
Th2 immune response
The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.
helper T cell differentiation
T-helper cell development
The expansion of a T cell population by cell division. Follows T cell activation.
T lymphocyte proliferation
T-cell proliferation
T-lymphocyte proliferation
The expansion of a B cell population by cell division. Follows B cell activation.
B lymphocyte proliferation
B-cell proliferation
B-lymphocyte proliferation
A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.
T lymphocyte receptor complex
T-cell receptor complex
T-lymphocyte receptor complex
TCR
TCR complex
Any process that activates or increases the rate or extent of T cell proliferation.
activation of T cell proliferation
positive regulation of T lymphocyte proliferation
positive regulation of T-lymphocyte proliferation
stimulation of T cell proliferation
up regulation of T cell proliferation
up-regulation of T cell proliferation
upregulation of T cell proliferation
The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
T lymphocyte activation
T-cell activation
T-lymphocyte activation
The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
B lymphocyte activation
B-cell activation
B-lymphocyte activation
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
macrophage polarization
The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
alginate metabolic process
alginate metabolism
alginic acid metabolism
The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid.
nitrate metabolism
Any process that modulates the frequency, rate or extent of cell proliferation.
regulation of cell proliferation
The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.
assimilatory nitrate reduction
Any process that modulates the frequency, rate or extent of T cell proliferation.
regulation of T lymphocyte proliferation
regulation of T-cell proliferation
regulation of T-lymphocyte proliferation
Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
down regulation of T cell proliferation
down-regulation of T cell proliferation
downregulation of T cell proliferation
inhibition of T cell proliferation
negative regulation of T lymphocyte proliferation
negative regulation of T-cell proliferation
negative regulation of T-lymphocyte proliferation
The fusion of two vacuole membranes to form a single vacuole.
homotypic vacuole fusion
homotypic vacuole fusion (non-autophagic)
homotypic vacuole fusion, non-autophagic
vacuole fusion (non-autophagic)
The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
retrograde (endosome to Golgi) transport
The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
D-loop biosynthesis
D-loop formation
displacement loop biosynthesis
displacement loop formation
Rad51-mediated strand invasion
strand invasion
The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.
lipoprotein metabolism
The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.
lipoprotein anabolism
lipoprotein biosynthesis
lipoprotein formation
lipoprotein synthesis
The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.
lipoprotein breakdown
lipoprotein catabolism
lipoprotein degradation
Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
telomere binding
telomeric repeat binding
The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
haem catabolic process
haem catabolism
heme breakdown
heme catabolism
heme degradation
The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
haem metabolic process
haem metabolism
heme metabolism
Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.
LPAAT activity
Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation.
down regulation of sporulation
down-regulation of sporulation
downregulation of sporulation
inhibition of sporulation
The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.
NE-ER continuum
NE-ER network
nuclear envelope-endoplasmic reticulum continuum
nuclear envelope-endoplasmic reticulum network
nuclear envelope-ER network
nuclear membrane-endoplasmic reticulum continuum
nuclear membrane-ER network
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
regulation of cellular protein breakdown
regulation of cellular protein catabolic process
regulation of cellular protein catabolism
regulation of cellular protein degradation
regulation of cyclin breakdown
regulation of cyclin catabolic process
regulation of cyclin catabolism
regulation of cyclin degradation
regulation of degradation of cyclin
regulation of protein breakdown
regulation of protein catabolism
regulation of protein degradation
Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process.
down regulation of cellular protein breakdown
down regulation of cellular protein catabolic process
down regulation of cellular protein catabolism
down regulation of cellular protein degradation
down regulation of protein catabolic process
down-regulation of cellular protein breakdown
down-regulation of cellular protein catabolic process
down-regulation of cellular protein catabolism
down-regulation of cellular protein degradation
down-regulation of protein catabolic process
downregulation of cellular protein breakdown
downregulation of cellular protein catabolic process
downregulation of cellular protein catabolism
downregulation of cellular protein degradation
downregulation of protein catabolic process
inhibition of cellular protein breakdown
inhibition of cellular protein catabolic process
inhibition of cellular protein catabolism
inhibition of cellular protein degradation
inhibition of protein catabolic process
negative regulation of cellular protein breakdown
negative regulation of cellular protein catabolic process
negative regulation of cellular protein catabolism
negative regulation of cellular protein degradation
negative regulation of protein breakdown
negative regulation of protein catabolism
negative regulation of protein degradation
The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organism exposed to it, carried out by individual cells. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
drug breakdown
drug catabolic process
drug catabolism
drug degradation
exogenous drug breakdown
exogenous drug catabolic process
exogenous drug catabolism
exogenous drug degradation
xenobiotic breakdown
xenobiotic catabolism
xenobiotic degradation
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
ketone metabolism
The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
ketone anabolism
ketone biosynthesis
ketone formation
ketone synthesis
The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
ketone breakdown
ketone catabolism
ketone degradation
The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.
xylene breakdown
xylene catabolism
xylene degradation
The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species.
methylmercury metabolism
The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen.
aerobic gallate breakdown
aerobic gallate catabolism
aerobic gallate degradation
aerobic gallic acid catabolic process
aerobic gallic acid catabolism
The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.
chlorinated hydrocarbon metabolism
The chemical reactions and pathways involving halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. Halogens include fluorine, chlorine, bromine and iodine.
halogenated hydrocarbon metabolism
The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.
nylon metabolism
The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives.
cyanuric acid metabolism
The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide.
cyromazine metabolic process
cyromazine metabolism
N-cyclopropylmelamine metabolism
The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.
toluene breakdown
toluene catabolism
toluene degradation
The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.
s-triazine compound breakdown
s-triazine compound catabolism
s-triazine compound degradation
The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.
chlorinated hydrocarbon breakdown
chlorinated hydrocarbon catabolism
chlorinated hydrocarbon degradation
The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms.
halogenated hydrocarbon breakdown
halogenated hydrocarbon catabolism
halogenated hydrocarbon degradation
The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.
cresol metabolism
hydroxytoluene metabolic process
hydroxytoluene metabolism
The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.
terpene metabolism
The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.
anaerobic phenol-containing compound metabolism
The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon.
phenanthrene breakdown
phenanthrene catabolism
phenanthrene degradation
The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.
amino acid derivative catabolic process
cellular amino acid derivative breakdown
cellular amino acid derivative catabolic process
cellular amino acid derivative catabolism
cellular amino acid derivative degradation
cellular modified amino acid breakdown
cellular modified amino acid catabolic process
cellular modified amino acid catabolism
cellular modified amino acid degradation
modified amino acid catabolism
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
response to chemical stimulus
response to chemical substance
The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore.
spore coat biosynthesis
spore coat biosynthetic process
spore wall formation
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
ribosome biogenesis and assembly
The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
ribosomal subunit assembly
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional cytosolic ribosome. Distinct stages of this process take place first in the nucleolus, then in the nucleus and finally in the cytosol.
mature ribosome assembly
The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
killer activity
natural killer cell mediated cell death
natural killer cell mediated cell killing
natural killer cell mediated cytolysis
natural killer-cell mediated cytolysis
NK cell mediated cell death
NK cell mediated cell killing
NK cell mediated cytolysis
NK cell mediated cytotoxicity
Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity.
regulation of natural killer cell mediated cell death
regulation of natural killer cell mediated cell killing
regulation of natural killer cell mediated cytolysis
regulation of natural killer-cell mediated cytolysis
regulation of NK cell mediated cell death
regulation of NK cell mediated cell killing
regulation of NK cell mediated cytolysis
regulation of NK cell mediated cytotoxicity
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
ribosomal large subunit biogenesis and assembly
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
ribosomal small subunit biogenesis and assembly
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate.
error-free PRR
error-free replication restart
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites.
error-prone postreplication DNA repair
mutagenic postreplication DNA repair
mutagenic PRR
The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
purine metabolic process
purine metabolism
purine nucleoside metabolism
Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
major histocompatibility complex binding
major histocompatibility complex ligand
Binding to a major histocompatibility complex class I molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
alpha-beta T cell receptor activity
gamma-delta T cell receptor activity
major histocompatibility complex class I binding
major histocompatibility complex class I ligand
T cell receptor activity
Binding to a major histocompatibility complex class II molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
major histocompatibility complex class II binding
major histocompatibility complex class II ligand
Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y = Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages.
ISG15 conjugating enzyme activity