NothingMuch/GO-Terms huggingface dataset:
Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin.
2-methylthio-cis-ribozeatin hydroxylase activity
tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity
tRNA-(ms2io6A)-hydroxylase activity
Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.
3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity
bile salt hydrolase activity
choloyltaurine hydrolase activity
glycocholase activity
Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate.
2,4-diaminobutyrate 4-aminotransferase activity
DAB aminotransferase activity
DABA aminotransferase activity
diaminibutyric acid aminotransferase activity
diaminobutyrate transaminase activity
diaminobutyrate--2-oxoglutarate aminotransferase activity
EctB
L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity
L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity
L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity
The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
nor-spermidine anabolism
nor-spermidine biosynthesis
nor-spermidine formation
nor-spermidine synthesis
Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.
activation of eye photoreceptor development
positive regulation of eye photoreceptor development
stimulation of eye photoreceptor development
up regulation of eye photoreceptor development
up-regulation of eye photoreceptor development
upregulation of eye photoreceptor development
Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development.
down regulation of eye photoreceptor development
down-regulation of eye photoreceptor development
downregulation of eye photoreceptor development
inhibition of eye photoreceptor development
negative regulation of eye photoreceptor development
A protein complex that binds interleukin-1; comprises an alpha and a beta subunit.
IL-1 receptor complex
The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
carnitine anabolism
carnitine biosynthesis
carnitine formation
carnitine synthesis
vitamin Bt biosynthesis
vitamin Bt biosynthetic process
The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.
farnesyl diphosphate breakdown
farnesyl diphosphate catabolism
farnesyl diphosphate degradation
Binding to a mercury ion (Hg2+).
Hg ion binding
mercury binding
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
down regulation of MHC class I biosynthetic process
down-regulation of MHC class I biosynthetic process
downregulation of MHC class I biosynthetic process
inhibition of MHC class I biosynthetic process
negative regulation of major histocompatibility complex class I biosynthesis
negative regulation of major histocompatibility complex class I biosynthetic process
negative regulation of MHC class I anabolism
negative regulation of MHC class I biosynthesis
negative regulation of MHC class I formation
negative regulation of MHC class I synthesis
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
activation of MHC class I biosynthetic process
positive regulation of major histocompatibility complex class I biosynthesis
positive regulation of major histocompatibility complex class I biosynthetic process
positive regulation of MHC class I anabolism
positive regulation of MHC class I biosynthesis
positive regulation of MHC class I formation
positive regulation of MHC class I synthesis
stimulation of MHC class I biosynthetic process
up regulation of MHC class I biosynthetic process
up-regulation of MHC class I biosynthetic process
upregulation of MHC class I biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
down regulation of MHC class II biosynthetic process
down-regulation of MHC class II biosynthetic process
downregulation of MHC class II biosynthetic process
inhibition of MHC class II biosynthetic process
negative regulation of major histocompatibility complex class II biosynthesis
negative regulation of major histocompatibility complex class II biosynthetic process
negative regulation of MHC class II anabolism
negative regulation of MHC class II biosynthesis
negative regulation of MHC class II formation
negative regulation of MHC class II synthesis
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
activation of MHC class II biosynthetic process
positive regulation of major histocompatibility complex class II biosynthesis
positive regulation of major histocompatibility complex class II biosynthetic process
positive regulation of MHC class II anabolism
positive regulation of MHC class II biosynthesis
positive regulation of MHC class II formation
positive regulation of MHC class II synthesis
stimulation of MHC class II biosynthetic process
up regulation of MHC class II biosynthetic process
up-regulation of MHC class II biosynthetic process
upregulation of MHC class II biosynthetic process
Blocks the binding of interleukin-1 to interleukin-1 type I receptors.
IL-1ra type I
Blocks the binding of interleukin-1 to interleukin-1 type II receptors.
IL-1ra type II
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
activation of nitric oxide biosynthetic process
positive regulation of nitric oxide anabolism
positive regulation of nitric oxide biosynthesis
positive regulation of nitric oxide formation
positive regulation of nitric oxide synthesis
stimulation of nitric oxide biosynthetic process
up regulation of nitric oxide biosynthetic process
up-regulation of nitric oxide biosynthetic process
upregulation of nitric oxide biosynthetic process
Catalysis of the reaction: a chalcone = a flavanone.
chalcone--flavonone isomerase activity
chalcone-flavanone isomerase activity
flavanone lyase (decyclizing)
Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.
dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity
flavonoid 2-oxoglutarate-dependent dioxygenase activity
FLS activity
The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.
male courtship behavior, song production
male courtship behaviour, song production
male courtship behaviour, veined wing generated song production
Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating.
down regulation of female receptivity, post-mating
down-regulation of female receptivity, post-mating
downregulation of female receptivity, post-mating
inhibition of female receptivity, post-mating
Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene).
lycopene cyclase
Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively.
crtL
lycopene cyclase
Catalysis of the reaction: H2O + uridine = ribofuranose + uracil.
uridine hydrolase activity
uridine ribohydrolase activity
Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.
ACV synthetase activity
Catalysis of the reaction: isopenicillin N = penicillin N.
isopenicillin N epimerase activity
penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity
Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O2 = CO2 + deacetylcephalosporin C + succinate.
3\'-methylcephem hydroxylase activity
beta-lactam hydroxylase activity
DACS
DAOC hydroxylase activity
deacetoxycephalosporin C hydroxylase activity
deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity
deacetylcephalosporin C synthase activity
Any process that maintains the redox environment of a cell or compartment within a cell.
regulation of cell redox homeostasis
regulation of redox homeostasis
Genetic recombination within the DNA of the genes coding for ribosomal RNA.
recombination within ribosomal DNA repeats
Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.
down regulation of R8 spacing
down-regulation of R8 spacing
downregulation of R8 spacing
inhibition of R8 spacing
The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor.
R8-mediated photoreceptor organisation
The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome.
vesicle-fusome targeting
Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide.
beta-galactose oxidase activity
D-galactose oxidase activity
D-galactose:oxygen 6-oxidoreductase activity
Catalysis of the reaction: 6-endo-hydroxycineole + NAD+ = 6-oxocineole + H+ + NADH.
6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene.
sesquiterpene cyclase activity
trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming)
trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase activity
trichodiene synthetase activity
Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.
2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)
sesquiterpene cyclase activity
trans,trans-farnesyl diphosphate aristolochene-lyase activity
trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)
Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine.
L-lysine aminotransferase activity
L-lysine transaminase activity
L-lysine-alpha-ketoglutarate 6-aminotransferase activity
L-lysine-alpha-ketoglutarate aminotransferase activity
L-lysine:2-oxoglutarate 6-aminotransferase activity
lysine 6-aminotransferase activity
lysine epsilon-aminotransferase activity
lysine epsilon-transaminase activity
lysine:2-ketoglutarate 6-aminotransferase activity
Catalysis of the reaction: 2-oxoglutarate + a (2S)-flavan-4-one + O2 = a (2R,3R)-dihydroflavonol + CO2 + succinate.
(2S)-flavanone 3-hydroxylase activity
flavanone 3-beta-hydroxylase activity
flavanone 3-hydroxylase activity
flavanone 3beta-hydroxylase activity
flavanone synthase I activity
flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
naringenin 3-dioxygenase activity
naringenin 3-hydroxylase activity
naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity
The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
gibberellic acid breakdown
gibberellic acid catabolic process
gibberellic acid catabolism
gibberellic acid degradation
gibberellin catabolism
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.
chemorepellant activity
Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IL-24 receptor activity
IL-24R
Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IL-25 receptor activity
IL-25R
Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IL-26 receptor activity
IL-26R
Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IL-27 receptor activity
IL-27R
Binding to interleukin-24.
IL-24 binding
Binding to interleukin-25.
IL-25 binding
Binding to interleukin-26.
IL-26 binding
Binding to interleukin-27.
IL-27 binding
Binding to an interleukin-16 receptor.
IL-16
interleukin-16 receptor ligand
Binding to an interleukin-18 receptor.
IL-18
interleukin-18 receptor ligand
Binding to an interleukin-19 receptor.
IL-19
interleukin-19 receptor ligand
Binding to an interleukin-20 receptor.
IL-20
interleukin-20 receptor ligand
Binding to an interleukin-22 receptor.
IL-22
interleukin-22 receptor ligand
Binding to an interleukin-23 receptor.
IL-23
interleukin-23 receptor ligand
Binding to an interleukin-24 receptor.
IL-24
interleukin-24 receptor ligand
Binding to an interleukin-25 receptor.
IL-25
interleukin-25 receptor ligand
Binding to an interleukin-26 receptor.
IL-26
interleukin-26 receptor ligand
Binding to an interleukin-27 receptor.
IL-27
interleukin-27 receptor ligand
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
down regulation of cholesterol biosynthetic process
down-regulation of cholesterol biosynthetic process
downregulation of cholesterol biosynthetic process
inhibition of cholesterol biosynthetic process
negative regulation of cholesterol anabolism
negative regulation of cholesterol biosynthesis
negative regulation of cholesterol formation
negative regulation of cholesterol synthesis
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
activation of cholesterol biosynthetic process
positive regulation of cholesterol anabolism
positive regulation of cholesterol biosynthesis
positive regulation of cholesterol formation
positive regulation of cholesterol synthesis
stimulation of cholesterol biosynthetic process
up regulation of cholesterol biosynthetic process
up-regulation of cholesterol biosynthetic process
upregulation of cholesterol biosynthetic process
Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2.
gibberellin 2-beta-hydroxylase activity
gibberellin 2-oxidase activity
gibberellin 2beta-dioxygenase activity
gibberellin 2beta-hydroxylase activity
Catalysis of the reaction: L-phenylalanine = NH4 + trans-cinnamate.
L-phenylalanine ammonia-lyase activity
PAL activity
phe ammonia-lyase activity
phenylalanine ammonium-lyase activity
phenylalanine deaminase activity
Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.
9-cis-epoxycarotenoid 11,12-dioxygenase activity
AtNCED3
NCED
neoxanthin cleavage enzyme
nine-cis-epoxycarotenoid dioxygenase activity
PvNCED1
VP14
Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+. Also acts on coniferyl alcohol, sinapyl alcohol and 4-coumaryl alcohol.
CAD activity
cinnamyl alcohol dehydrogenase activity
cinnamyl-alcohol:NADP+ oxidoreductase activity
Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+.
cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase activity
dihydroflavanol 4-reductase activity
dihydroflavonol 4-reductase activity
dihydromyricetin reductase activity
dihydroquercetin reductase activity
NADPH-dihydromyricetin reductase activity
Binding to TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.
Apo-2L binding
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.
down regulation of imaginal disc growth
down-regulation of imaginal disc growth
downregulation of imaginal disc growth
inhibition of imaginal disc growth
Any process that activates or increases the frequency, rate or extent of imaginal disc growth.
activation of imaginal disc growth
stimulation of imaginal disc growth
up regulation of imaginal disc growth
up-regulation of imaginal disc growth
upregulation of imaginal disc growth
The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
sterigmatocystin breakdown
sterigmatocystin catabolism
sterigmatocystin degradation
Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation.
down regulation of cytotoxic T cell differentiation
down-regulation of cytotoxic T cell differentiation
downregulation of cytotoxic T cell differentiation
inhibition of cytotoxic T cell differentiation
negative regulation of cytotoxic T cell development
negative regulation of cytotoxic T lymphocyte differentiation
negative regulation of cytotoxic T-cell differentiation
negative regulation of cytotoxic T-lymphocyte differentiation
Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation.
activation of cytotoxic T cell differentiation
positive regulation of cytotoxic T cell development
positive regulation of cytotoxic T lymphocyte differentiation
positive regulation of cytotoxic T-cell differentiation
positive regulation of cytotoxic T-lymphocyte differentiation
stimulation of cytotoxic T cell differentiation
up regulation of cytotoxic T cell differentiation
up-regulation of cytotoxic T cell differentiation
upregulation of cytotoxic T cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation.
down regulation of gamma-delta T cell differentiation
down-regulation of gamma-delta T cell differentiation
downregulation of gamma-delta T cell differentiation
inhibition of gamma-delta T cell differentiation
negative regulation of gamma-delta T cell development
negative regulation of gamma-delta T lymphocyte differentiation
negative regulation of gamma-delta T-cell differentiation
negative regulation of gamma-delta T-lymphocyte differentiation
Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.
activation of gamma-delta T cell differentiation
positive regulation of gamma-delta T cell development
positive regulation of gamma-delta T lymphocyte differentiation
positive regulation of gamma-delta T-cell differentiation
positive regulation of gamma-delta T-lymphocyte differentiation
stimulation of gamma-delta T cell differentiation
up regulation of gamma-delta T cell differentiation
up-regulation of gamma-delta T cell differentiation
upregulation of gamma-delta T cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation.
down regulation of cumulus cell differentiation
down-regulation of cumulus cell differentiation
downregulation of cumulus cell differentiation
inhibition of cumulus cell differentiation
negative regulation of ovarian cumulus cell differentiation
Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation.
activation of cumulus cell differentiation
positive regulation of ovarian cumulus cell differentiation
stimulation of cumulus cell differentiation
up regulation of cumulus cell differentiation
up-regulation of cumulus cell differentiation
upregulation of cumulus cell differentiation
Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation.
activation of auditory receptor cell differentiation
positive regulation of auditory hair cell differentiation
positive regulation of auditory receptor cell differentiation
stimulation of auditory receptor cell differentiation
up regulation of auditory receptor cell differentiation
up-regulation of auditory receptor cell differentiation
upregulation of auditory receptor cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation.
down regulation of plasmatocyte differentiation
down-regulation of plasmatocyte differentiation
downregulation of plasmatocyte differentiation
inhibition of plasmatocyte differentiation
Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation.
activation of plasmatocyte differentiation
stimulation of plasmatocyte differentiation
up regulation of plasmatocyte differentiation
up-regulation of plasmatocyte differentiation
upregulation of plasmatocyte differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.
down regulation of keratinocyte differentiation
down-regulation of keratinocyte differentiation
downregulation of keratinocyte differentiation
inhibition of keratinocyte differentiation
Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.
activation of keratinocyte differentiation
stimulation of keratinocyte differentiation
up regulation of keratinocyte differentiation
up-regulation of keratinocyte differentiation
upregulation of keratinocyte differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.
down regulation of T-helper 1 cell differentiation
down-regulation of T-helper 1 cell differentiation
downregulation of T-helper 1 cell differentiation
inhibition of T-helper 1 cell differentiation
negative regulation of T-helper 1 cell development
Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.
activation of T-helper 1 cell differentiation
positive regulation of T-helper 1 cell development
stimulation of T-helper 1 cell differentiation
up regulation of T-helper 1 cell differentiation
up-regulation of T-helper 1 cell differentiation
upregulation of T-helper 1 cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.
down regulation of T-helper 2 cell differentiation
down-regulation of T-helper 2 cell differentiation
downregulation of T-helper 2 cell differentiation
inhibition of T-helper 2 cell differentiation
negative regulation of T-helper 2 cell development
Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.
activation of T-helper 2 cell differentiation
positive regulation of T-helper 2 cell development
stimulation of T-helper 2 cell differentiation
up regulation of T-helper 2 cell differentiation
up-regulation of T-helper 2 cell differentiation
upregulation of T-helper 2 cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation.
down regulation of basophil differentiation
down-regulation of basophil differentiation
downregulation of basophil differentiation
inhibition of basophil differentiation
Any process that activates or increases the frequency, rate or extent of basophil differentiation.
activation of basophil differentiation
stimulation of basophil differentiation
up regulation of basophil differentiation
up-regulation of basophil differentiation
upregulation of basophil differentiation