NothingMuch/GO-Terms huggingface dataset:
Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
down regulation of DNA damage response, signal transduction by p53 class mediator
down-regulation of DNA damage response, signal transduction by p53 class mediator
downregulation of DNA damage response, signal transduction by p53 class mediator
inhibition of DNA damage response, signal transduction by p53 class mediator
negative regulation of p53 induced by DNA damage response
Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.
regulation of myosin II filament assembly or disassembly
regulation of myosin II filament organisation
Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
regulation of apoptosis of neuronal cells
regulation of apoptosis of neurons
regulation of neuron apoptosis
regulation of neuron programmed cell death
regulation of neuronal cell programmed cell death
regulation of programmed cell death of neuronal cells
regulation of programmed cell death, neurons
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
down regulation of neuron apoptosis
down-regulation of neuron apoptosis
downregulation of neuron apoptosis
inhibition of neuron apoptosis
negative regulation of neuron apoptosis
negative regulation of programmed cell death, neurons
neuron survival
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
activation of neuron apoptosis
positive regulation of neuron apoptosis
positive regulation of programmed cell death, neurons
stimulation of neuron apoptosis
up regulation of neuron apoptosis
up-regulation of neuron apoptosis
upregulation of neuron apoptosis
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
activation of blood vessel endothelial cell migration
stimulation of blood vessel endothelial cell migration
up regulation of blood vessel endothelial cell migration
up-regulation of blood vessel endothelial cell migration
upregulation of blood vessel endothelial cell migration
Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
down regulation of blood vessel endothelial cell migration
down-regulation of blood vessel endothelial cell migration
downregulation of blood vessel endothelial cell migration
inhibition of blood vessel endothelial cell migration
Binds to and increases the activity of a protein serine/threonine kinase.
protein ser/thr kinase activator activity
The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.
protein amino acid acylation
The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Moco metabolic process
Moco metabolism
molybdopterin cofactor metabolism
Any process that activates or increases the activity of a GTPase.
activation of GTPase activity
positive regulation of ARF GTPase activity
positive regulation of Cdc42 GTPase activity
positive regulation of Rab GTPase activity
positive regulation of Rac GTPase activity
positive regulation of Ral GTPase activity
positive regulation of Ran GTPase activity
positive regulation of Rap GTPase activity
positive regulation of Ras GTPase activity
positive regulation of Rho GTPase activity
stimulation of ARF GTPase activity
stimulation of Cdc42 GTPase activity
stimulation of GTPase activity
stimulation of Rab GTPase activity
stimulation of Rac GTPase activity
stimulation of Ral GTPase activity
stimulation of Ran GTPase activity
stimulation of Rap GTPase activity
stimulation of Ras GTPase activity
stimulation of Rho GTPase activity
up regulation of ARF GTPase activity
up regulation of Cdc42 GTPase activity
up regulation of GTPase activity
up regulation of Rab GTPase activity
up regulation of Rac GTPase activity
up regulation of Ral GTPase activity
up regulation of Ran GTPase activity
up regulation of Rap GTPase activity
up regulation of Ras GTPase activity
up regulation of Rho GTPase activity
up-regulation of ARF GTPase activity
up-regulation of Cdc42 GTPase activity
up-regulation of GTPase activity
up-regulation of Rab GTPase activity
up-regulation of Rac GTPase activity
up-regulation of Ral GTPase activity
up-regulation of Ran GTPase activity
up-regulation of Rap GTPase activity
up-regulation of Ras GTPase activity
up-regulation of Rho GTPase activity
upregulation of ARF GTPase activity
upregulation of Cdc42 GTPase activity
upregulation of GTPase activity
upregulation of Rab GTPase activity
upregulation of Rac GTPase activity
upregulation of Ral GTPase activity
upregulation of Ran GTPase activity
upregulation of Rap GTPase activity
upregulation of Ras GTPase activity
upregulation of Rho GTPase activity
Binding to a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.
phosphoinositide 3-kinase binding
PI3K binding
Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
translational stress response
Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress.
regulation of translation initiation in response to stress
Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
sequence specific DNA binding
Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling.
regulation of IGF receptor signaling pathway
regulation of IGF receptor signalling pathway
regulation of insulin-like growth factor receptor signalling pathway
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane.
nuclear matrix organisation
nuclear matrix organization and biogenesis
nucleoskeleton organization
The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores.
sporangia development
The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.
hearing organ development
The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).
nasus development
The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
glossa development
lingua development
The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
glossa morphogenesis
lingua morphogenesis
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
animal skin development
The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer.
endospore wall
peptidoglycan-based spore wall
spore wall
A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species.
nuclear RFC
A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins.
prokaryotic replisome
The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.
amide metabolism
cellular amide metabolic process
The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
cellular amide catabolic process
The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid.
formamide metabolism
The chemical reactions and pathways involving isoprene, C5H8.
2-methyl-1,3-butadiene metabolic process
2-methyl-1,3-butadiene metabolism
hemiterpene metabolic process
hemiterpene metabolism
isoprene metabolism
The chemical reactions and pathways resulting in the formation of isoprene, C5H8.
2-methyl-1,3-butadiene biosynthesis
2-methyl-1,3-butadiene biosynthetic process
hemiterpene biosynthesis
hemiterpene biosynthetic process
The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.
astrocyte migration
astrocytic glial cell migration
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
response to 17alpha-ethynylestradiol
response to estrogen stimulus
response to oestrogen stimulus
Any process involved in forming the mature 3' end of a regulatory non-coding RNA molecule.
ncRNA 3\' end processing
ncRNA 3\'-end processing
small regulatory ncRNA 3\'-end processing
The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.
poly(A)-dependent ncRNA catabolic process
The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.
puromycin metabolism
The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
benzoate breakdown
benzoate catabolism
benzoate degradation
The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.
novobiocin metabolism
The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
tetracyclin metabolic process
tetracyclin metabolism
tetracycline metabolism
The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.
cephalosporin metabolism
The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
inositol phosphate metabolism
myo-inositol phosphate metabolic process
myo-inositol phosphate metabolism
The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
dicarboxylate metabolic process
dicarboxylate metabolism
dicarboxylic acid metabolism
The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
dicarboxylate catabolic process
dicarboxylate catabolism
dicarboxylic acid breakdown
dicarboxylic acid catabolism
dicarboxylic acid degradation
The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
dicarboxylate biosynthesis
dicarboxylate biosynthetic process
dicarboxylic acid anabolism
dicarboxylic acid biosynthesis
dicarboxylic acid formation
dicarboxylic acid synthesis
The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
engulfment of apoptotic cell corpse
engulfment of cell corpse
The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream.
extracellular space of host
That space within the plasma membrane of a host cell.
host intracellular
intracellular region of host
The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine.
microspore wall
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
axon terminal
axon terminal specialization
nerve ending
The assembly from its constituent parts of a type IV pilus.
type IV fimbria assembly
type IV fimbria biogenesis
type IV fimbriae assembly
type IV fimbriae biogenesis
type IV fimbrial assembly
type IV fimbrial biogenesis
type IV fimbrium assembly
type IV fimbrium biogenesis
type IV pilus biogenesis
The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome.
co-translational amino acid modification
co-translational modification
cotranslational amino acid modification
cotranslational modification
cotranslational protein modification
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
post-translational amino acid modification
post-translational modification
posttranslational amino acid modification
posttranslational modification
posttranslational protein modification
PTM
The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure.
monoterpene metabolism
The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure.
monoterpene biosynthesis
The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure.
monoterpene catabolism
The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.
cell adhesion during biofilm formation
The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
cell adhesion during single-species biofilm formation
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies.
pilus organisation
pilus organization and biogenesis
Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site.
DNA-3-methyladenine glycosylase III
Mag III
MagIII
Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates.
F420-0 gamma-glutamyl ligase activity
A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
clamp loader complex
DNA polymerase III, DnaX complex
DNA polymerase III, DnaX subcomplex
Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
cyclic nucleotide activated ion channel activity
cyclic nucleotide gated ion channel activity
cyclic nucleotide-gated ion channel activity
cyclic nucleotide-gated monoatomic ion channel activity
Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
cphA
Enables the transfer of methionine from one side of a membrane to the other.
methionine importer
methionine importer activity
methionine importing activity
methionine-importing activity
Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+.
D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)
glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity
triosephosphate dehydrogenase (NAD(P))
triosephosphate dehydrogenase (NAD(P)+)
Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).
acetate permease
acetate-cation symporter activity
acetate/cation symporter activity
acetate:cation symporter activity
ActP
cation-acetate symporter activity
cation/acetate symporter activity
cation:acetate symporter activity
Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.
regulation of interspecies interactions between organisms
regulation of symbiosis, encompassing mutualism through parasitism
regulation of symbiotic process
Any process in which a host organism modulates the frequency, rate or extent of viral transcription.
regulation by host of viral transcription
regulation of viral transcription by host
Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription.
negative regulation of viral transcription by host
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.
ossification involved in bone modeling
ossification involved in skeletal development
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
cellular macromolecular complex organization
cellular macromolecular complex subunit organisation
cellular macromolecular complex subunit organization
macromolecular complex organization
macromolecular complex subunit organisation
macromolecular complex subunit organization
protein complex subunit organisation
protein complex subunit organization
protein-containing complex subunit organization
The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.
asexual reproduction resulting in the formation of a cellular spore
asexual sporulation resulting in the formation of a viable spore
Any process which modulates the frequency, rate or extent of cAMP-mediated signaling.
regulation of cAMP-mediated signalling
The organization process that preserves a cellular component in a stable functional or structural state.
cellular component maintenance at cellular level
Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.
H2A histone acetylase activity
H2A histone acetyltransferase activity
H2A histone lysine N-acetyltransferase activity
The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
migration within host
A process in which a symbiont alters or subverts a biological process in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
disruption by symbiont of host cell
modification by symbiont of host biological process
modification by symbiont of host morphology or physiology
modulation by symbiont of host system process
pathogenesis
regulation by symbiont of host system process
A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
auto-aggregation
bfp-dependent aggregation
bundle-forming fimbriae-dependent aggregation
bundle-forming pili-dependent aggregation
tfp-dependent aggregation
type IV pili-dependent aggregation
Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.
H2B histone acetylase activity
H2B histone acetyltransferase activity
H2B histone lysine N-acetyltransferase activity