NothingMuch/GO-Terms huggingface dataset:
Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.
optic lobe and Bolwig\'s organ precursor formation
optic lobe placode formation
Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.
cytosolic retinal dehydrogenase activity
retinal:NAD+ oxidoreductase activity
Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H+ = 2-aminomuconate 6-semialdehyde + CO2.
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity
2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity
ACMSD activity
alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity
picolinic acid carboxylase activity
picolinic acid decarboxylase activity
Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.
beta-alanine transporter activity
The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.
B cell polarization
B lymphocyte polarization
B-cell polarization
establishment of B lymphocyte polarity
establishment of B-cell polarity
establishment of B-lymphocyte polarity
The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.
establishment of NK cell polarity
natural killer cell polarization
NK cell polarization
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
c-SMAC
supramolecular activation cluster
Binding to a phosphorylated tyrosine residue within a protein.
phosphotyrosine binding
Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.
PGJ receptor activity
PGJ(2) receptor activity
Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.
down regulation of type IIb hypersensitivity
down-regulation of type IIb hypersensitivity
downregulation of type IIb hypersensitivity
inhibition of type IIb hypersensitivity
Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.
activation of type IIb hypersensitivity
stimulation of type IIb hypersensitivity
up regulation of type IIb hypersensitivity
up-regulation of type IIb hypersensitivity
upregulation of type IIb hypersensitivity
Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.
down regulation of type III hypersensitivity
down-regulation of type III hypersensitivity
downregulation of type III hypersensitivity
inhibition of type III hypersensitivity
Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.
activation of type III hypersensitivity
stimulation of type III hypersensitivity
up regulation of type III hypersensitivity
up-regulation of type III hypersensitivity
upregulation of type III hypersensitivity
Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response.
down regulation of type IV hypersensitivity
down-regulation of type IV hypersensitivity
downregulation of type IV hypersensitivity
inhibition of type IV hypersensitivity
Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.
activation of type IV hypersensitivity
stimulation of type IV hypersensitivity
up regulation of type IV hypersensitivity
up-regulation of type IV hypersensitivity
upregulation of type IV hypersensitivity
Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.
down regulation of type I hypersensitivity
down-regulation of type I hypersensitivity
downregulation of type I hypersensitivity
inhibition of type I hypersensitivity
Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response.
activation of type I hypersensitivity
stimulation of type I hypersensitivity
up regulation of type I hypersensitivity
up-regulation of type I hypersensitivity
upregulation of type I hypersensitivity
Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.
down regulation of antibody-dependent cellular cytotoxicity
down-regulation of antibody-dependent cellular cytotoxicity
downregulation of antibody-dependent cellular cytotoxicity
inhibition of antibody-dependent cellular cytotoxicity
negative regulation of antibody dependent cell death
negative regulation of antibody dependent cell killing
negative regulation of antibody-dependent cell death
negative regulation of antibody-dependent cell killing
Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity.
activation of antibody-dependent cellular cytotoxicity
positive regulation of antibody dependent cell death
positive regulation of antibody dependent cell killing
positive regulation of antibody-dependent cell death
positive regulation of antibody-dependent cell killing
stimulation of antibody-dependent cellular cytotoxicity
up regulation of antibody-dependent cellular cytotoxicity
up-regulation of antibody-dependent cellular cytotoxicity
upregulation of antibody-dependent cellular cytotoxicity
The cell fate commitment of precursor cells that will become trophectoderm cells.
trophectoderm cell fate commitment
The morphogenesis of trophectoderm cells.
trophectoderm cellular morphogenesis
Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.
down regulation of complement activation, lectin pathway
down-regulation of complement activation, lectin pathway
downregulation of complement activation, lectin pathway
inhibition of complement activation, lectin pathway
negative regulation of complement cascade, lectin pathway
Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.
activation of complement activation, lectin pathway
positive regulation of complement cascade, lectin pathway
stimulation of complement activation, lectin pathway
up regulation of complement activation, lectin pathway
up-regulation of complement activation, lectin pathway
upregulation of complement activation, lectin pathway
Binding to a (1->3)-beta-D-glucan.
1,3-beta-D-glucan binding
callose binding
zymosan binding
Combining with (1->3)-beta-D-glucans to initiate an innate immune response.
(1,3)-beta-D-glucan receptor activity
(1->3)-beta-D-glucan receptor activity
1,3-beta-D-glucan receptor activity
beta-1,3-D-glucan receptor activity
zymosan receptor activity
Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
endotoxin receptor activity
lipopolysaccharide receptor activity
LPS receptor activity
Binding to lipoarabinomannan.
LAM binding
Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response.
LAM receptor activity
lipoarabinomannan receptor activity
Catalysis of the reaction: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl- + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl- + H+ + UDP.
alpha-1,4-N-acetylglucosaminyltransferase activity
alpha-N-acetylglucosaminyltransferase I activity
alpha1,4-N-acetylglucosaminyltransferase activity
glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity
UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity
Any process that stops, prevents, or reduces the rate of receptor recycling.
down regulation of receptor recycling
down-regulation of receptor recycling
downregulation of receptor recycling
inhibition of receptor recycling
Any process that activates or increases the frequency, rate or extent of receptor recycling.
activation of receptor recycling
stimulation of receptor recycling
up regulation of receptor recycling
up-regulation of receptor recycling
upregulation of receptor recycling
The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
B-1 B lymphocyte homeostasis
B-1 B-cell homeostasis
B-1 B-lymphocyte homeostasis
Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.
down regulation of B-1 B cell differentiation
down-regulation of B-1 B cell differentiation
downregulation of B-1 B cell differentiation
inhibition of B-1 B cell differentiation
negative regulation of B-1 B cell development
negative regulation of B-1 B lymphocyte differentiation
negative regulation of B-1 B-cell differentiation
negative regulation of B-1 B-lymphocyte differentiation
Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.
activation of B-1 B cell differentiation
positive regulation of B-1 B cell development
positive regulation of B-1 B lymphocyte differentiation
positive regulation of B-1 B-cell differentiation
positive regulation of B-1 B-lymphocyte differentiation
stimulation of B-1 B cell differentiation
up regulation of B-1 B cell differentiation
up-regulation of B-1 B cell differentiation
upregulation of B-1 B cell differentiation
Any process that stops, prevents, or reduces the rate or extent of exocyst assembly.
down regulation of exocyst assembly
down-regulation of exocyst assembly
downregulation of exocyst assembly
inhibition of exocyst assembly
Any process that increases the rate or extent of exocyst assembly.
activation of exocyst assembly
stimulation of exocyst assembly
up regulation of exocyst assembly
up-regulation of exocyst assembly
upregulation of exocyst assembly
Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.
isoglobotriaosylceramide synthase
Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.
G-alpha protein subunit binding
The directed movement of an animal in response to touch.
stereotaxis
taxis in response to mechanical stimulus
taxis in response to touch stimulus
Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.
nursing behavior
Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
activation of activation of membrane attack complex
positive regulation of activation of MAC
positive regulation of activation of TCC
positive regulation of activation of terminal complement complex
positive regulation of activation of the terminal complement cascade
positive regulation of MAC assembly
positive regulation of MAC formation
positive regulation of membrane attack complex assembly
positive regulation of membrane attack complex formation
stimulation of activation of membrane attack complex
up regulation of activation of membrane attack complex
up-regulation of activation of membrane attack complex
upregulation of activation of membrane attack complex
Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
down regulation of activation of membrane attack complex
down-regulation of activation of membrane attack complex
downregulation of activation of membrane attack complex
inhibition of activation of membrane attack complex
negative regulation of activation of MAC
negative regulation of activation of TCC
negative regulation of activation of terminal complement complex
negative regulation of activation of the terminal complement cascade
negative regulation of MAC assembly
negative regulation of MAC formation
negative regulation of membrane attack complex assembly
negative regulation of membrane attack complex formation
An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure.
vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure
Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure.
down regulation of heart contraction rate in baroreceptor response to increased blood pressure
down-regulation of heart contraction rate in baroreceptor response to increased blood pressure
downregulation of heart contraction rate in baroreceptor response to increased blood pressure
inhibition of heart contraction rate in baroreceptor response to increased blood pressure
negative control of heart contraction rate in baroreceptor response to increased blood pressure
negative regulation of cardiac contraction rate in baroreceptor response to increased blood pressure
negative regulation of heart contraction rate in baroreceptor response to increased blood pressure
Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.
decreased force of heart contraction during baroreceptor response to increased systemic arterial blood pressure
decreased strength of cardiac contraction during baroreceptor response to increased blood pressure
Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.
activation of heart contraction rate in baroreceptor response to decreased blood pressure
positive control of heart contraction rate in baroreceptor response to decreased blood pressure
positive regulation of cardiac contraction rate in baroreceptor response to decreased blood pressure
positive regulation of heart contraction rate in baroreceptor response to decreased blood pressure
stimulation of heart contraction rate in baroreceptor response to decreased blood pressure
up regulation of heart contraction rate in baroreceptor response to decreased blood pressure
up-regulation of heart contraction rate in baroreceptor response to decreased blood pressure
upregulation of heart contraction rate in baroreceptor response to decreased blood pressure
A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure.
noradrenaline-adrenaline vasoconstriction involved in regulation of blood pressure
norepinephrine-epinephrine vasoconstriction during blood pressure control
norepinephrine-epinephrine vasoconstriction during blood pressure regulation
norepinephrine-epinephrine vasoconstriction during control of blood pressure
The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.
noradrenaline-adrenalin catabolic process in blood stream
The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream.
angiotensin mediated vasoconstriction during blood pressure control
angiotensin mediated vasoconstriction during blood pressure regulation
angiotensin mediated vasoconstriction during control of blood pressure
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood.
angiotensin catabolic process in blood
The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure.
secretion of vasopressin during fast control of blood pressure
secretion of vasopressin during fast regulation of systemic arterial blood pressure
The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream.
vasopressin mediated vasoconstriction involved in systemic arterial blood pressure control
The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.
excitation of vasomotor center by baroreceptor signalling
A process that controls blood pressure by sensing the amount of stretch occurring in the atria.
atrial baroreceptor regulation of systemic arterial blood pressure
atrial control of blood pressure
atrial low pressure baroreceptor regulation of blood pressure
atrial reflex
The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume.
aldosterone mediated control of body fluids
aldosterone mediated regulation of blood volume
renal regulation of blood volume by aldosterone
The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.
renin-angiotensin control of aldosterone production
A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change.
noradrenaline-adrenaline vasodilation involved in regulation of blood pressure
norepinephrine-epinephrine vasodilation during blood pressure regulation
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
The process that increases the diameter of a blood vessel via the renin-angiotensin system.
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
Binding to an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.
metarhodopsin binding
The chemical reactions and pathways involving the siderochrome pyoverdine.
pyoverdine metabolism
Any process that activates or increases the rate of neuroblast proliferation.
activation of neuroblast proliferation
stimulation of neuroblast proliferation
up regulation of neuroblast proliferation
up-regulation of neuroblast proliferation
upregulation of neuroblast proliferation
Binding to adenine, a purine base.
6-aminopurine binding
The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.
membrane fusion involved in the acrosomal reaction
A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.
neurological control of breathing
regulation of respiratory gaseous exchange by neurological system process
A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).
caveolar macromolecular signalling complex
Binding to an interleukin-33 receptor.
IL-33
interleukin-33 receptor ligand
Binding to interleukin-33.
IL-33 binding
Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IL-33 receptor activity
IL-33R
A stable binary complex of a semaphorin and a plexin, together forming a functional semaphorin receptor.
plexin-neurophilin complex
Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.
inter-male aggression
Aggressive behavior associated with attempts to flee from a threat.
fear-induced aggression
Aggressive behavior induced by frustration and directed against an available target.
irritable aggression
Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.
territorial aggression
Aggressive behavior of a female to protect her offspring from a threat.
maternal aggression
Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation.
instrumental aggression
The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position.
wobble position m5C biosynthesis
A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets.
Ctu1-Ctu2 complex
tRNA thiouridylase
Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H+.
HMP-PP diphosphatase
HMP-PP pyrophosphatase
The chemical reactions and pathways resulting in the formation of hypochlorous acid.
HClO biosynthetic process
HOCl biosynthetic process
hypochlorite biosynthetic process
hypochlorous acid biosynthesis
The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.
HClO catabolic process
HOCl catabolic process
hypochlorite catabolic process
hypochlorous acid catabolism
Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
G quadruplex binding
G quartet binding
G quartet RNA binding
G-quartet binding
Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.
SRA binding
Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway.
negative regulation of thyroid hormone mediated signaling pathway
negative regulation of thyroid hormone mediated signalling pathway
Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.
positive regulation of thyroid hormone mediated signaling pathway
positive regulation of thyroid hormone mediated signalling pathway
Binding to dystroglycan, a glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).
alpha-dystroglycan binding
beta-dystroglycan binding
Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
high affinity IgA receptor activity