NothingMuch/GO-Terms huggingface dataset:
Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.
anthocyanidin synthase activity
leucoanthocyanidin dioxygenase activity
leucoanthocyanidin hydroxylase
leucocyanidin,2-oxoglutarate:oxygen oxidoreductase activity
Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2.
D17H activity
deacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)
desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-hydroxylating) activity
desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)
desacetoxyvindoline-4-hydroxylase activity
desacetyoxyvindoline-17-hydroxylase activity
Catalysis of the reaction: H+ + NADPH + O2 + quinine = 3-hydroxyquinine + H2O + NADP+.
nifedipine oxidase activity
quinine 3-hydroxylase activity
quinine,NADPH:oxygen oxidoreductase activity
Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H+ + NADPH + O2 = (S)-4-hydroxymandelonitrile + 2 H2O + NADP+.
(Z)-4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity
4-hydroxybenzeneacetaldehyde oxime monooxygenase activity
4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity
CYP71E1 activity
cytochrome P450-II-dependent monooxygenase activity
cytochrome P450II-dependent monooxygenase activity
NADPH-cytochrome P450 reductase (CYP71E1)
Catalysis of the reaction: (S)-N-methylcoclaurine + H+ + NADPH + O2 = (S)-3'-hydroxy-N-methylcoclaurine + H2O + NADP+.
(S)-N-methylcoclaurine 3\'-hydroxylase activity
(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3\'-hydroxylating)
cytochrome P450 80B1 activity
N-methylcoclaurine 3\'-hydroxylase activity
Catalysis of the reaction: H+ + NADPH + O2 + tabersonine = 16-hydroxytabersonine + H2O + NADP+.
tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating)
Catalysis of the reaction: H+ + NADPH + O2 + vinorine = H2O + NADP+ + vomilenine.
vinorine,NADPH:oxygen oxidoreductase (21alpha-hydroxylating)
Catalysis of the reaction: H+ + NADPH + O2 + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H2O + NADP+.
5-alpha-taxadienol-10-beta-hydroxylase activity
taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating)
taxane 10b-hydroxylase activity
taxane 10beta-hydroxylase activity
Catalysis of the reaction: H+ + NADPH + O2 + taxa-4(20),11-dien-5alpha-ol = H2O + NADP+ + taxa-4(20),11-dien-5alpha,13alpha-diol.
taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating)
taxane 13a-hydroxylase activity
taxane 13alpha-hydroxylase activity
Catalysis of the reaction: 2-oxoglutarate + O2 + penicillin N = CO2 + deacetoxycephalosporin C + H2O + succinate.
DAOC synthase activity
DAOCS activity
deacetoxycephalosporin C synthetase activity
expandase activity
penicillin N expandase activity
penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)
Catalysis of the reaction: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)- + 2 H+ + O2 = an (11E)-delta11-fatty acyl-CoA + 2 Fe(III)- + 2 H2O.
acyl-CoA delta11-desaturase activity
myristoyl-CoA 11-(E) desaturase activity
Catalysis of the reaction: AH(2) + O2 + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O + H+.
thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase activity
thiophene-2-carboxyl-CoA dehydrogenase activity
thiophene-2-carboxyl-CoA hydroxylase activity
thiophene-2-carboxyl-CoA monooxygenase activity
Catalysis of the reaction: AH2 + O2 + taxa-4,11-diene = A + H2O + taxa-4(20),11-dien-5alpha-ol.
taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating)
taxadiene 5a-hydroxylase activity
taxadiene 5alpha-hydroxylase activity
Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.
desulfoferrodoxin activity
neelaredoxin activity
rubredoxin:superoxide oxidoreductase activity
Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP+ = 2-oxo-2H-pyran-4,6-dicarboxylate + H+ + NADPH.
2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase activity
4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP(+) oxidoreductase activity
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase activity
alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase activity
Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+.
formaldehyde:NAD+ oxidoreductase (mycothiol-formylating)
NAD/factor-dependent formaldehyde dehydrogenase activity
Catalysis of the reaction: H2O + NAD+ + vanillin = 2 H+ + NADH + vanillate.
vanillin:NAD+ oxidoreductase activity
Catalysis of the reaction: H2O + NAD+ + phosphonate = 2 H+ + NADH + phosphate.
NAD-dependent phosphite dehydrogenas activity
NAD:phosphite oxidoreductase activity
phosphite dehydrogenase activity
phosphonate:NAD+ oxidoreductase activity
Catalysis of the reaction: 2 glutathione + H+ + methylarsonate = glutathione disulfide + H2O + methylarsonous acid.
glutathione:methylarsonate oxidoreductase activity
MMA(V) reductase activity
Catalysis of the reaction: H2O + arsenite + 2 oxidized azurin = 2 H+ + 2 reduced azurin + arsenate.
arsenite oxidase activity
arsenite:azurin oxidoreductase activity
Catalysis of the reaction: A + arsenite + H2O = AH(2) + arsenate + 2 H+.
arsenate:(acceptor) oxidoreductase activity
arsenate:acceptor oxidoreductase activity
Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity
C-14 sterol reductase activity
D14-sterol reductase activity
sterol C-14 reductase activity
sterol C14-reductase activity
Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.
D24-sterol reductase activity
lanosterol Delta(24)-reductase activity
lanosterol delta24-reductase activity
sterol:NADP+ delta24-oxidoreductase activity
Catalysis of the reaction: 17-O-acetylnorajmaline + NADP+ = 1,2-dihydrovomilenine + H+ + NADPH.
17-O-acetylnorajmaline:NADP+ oxidoreductase activity
Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O.
loganin:oxygen oxidoreductase (ring-cleaving)
Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
PebA
Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin.
(3Z)-phycoerythrobilin:ferredoxin oxidoreductase activity
PebB
Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
(3Z)-phytochromobilin:ferredoxin oxidoreductase activity
HY2
P-Phi-B synthase activity
PFB synthase activity
phytochromobilin synthase activity
PPhiB synthase activity
Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
(3Z)-phycocyanobilin:ferredoxin oxidoreductase activity
Catalysis of the reaction: L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2 + H+.
L-tryptophan 2\',3\'-oxidase activity
L-tryptophan alpha,beta-dehydrogenase activity
L-tryptophan:oxygen alpha,beta-oxidoreductase activity
tryptophan a,b-oxidase activity
Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.
glycine:acceptor oxidoreductase (hydrogen-cyanide-forming)
HCN synthase activity
hydrogen cyanide synthase activity
Catalysis of the reaction: (R)-canadine + 2 NADP+ = berberine + H+ + 2 NADPH.
(R)-canadine synthase activity
(R)-tetrahydroberberine:NADP+ oxidoreductase activity
Catalysis of the reaction: 1,2-dihydrovomilenine + NADP+ = H+ + NADPH + vomilenine.
1,2-dihydrovomilenine:NADP+ oxidoreductase activity
Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H+ + NADH = benzene-1,2,4-triol + NAD+.
1,2,4-trihydroxybenzene:NAD oxidoreductase activity
1,2,4-trihydroxybenzene:NAD+ oxidoreductase activity
2-hydroxy-1,4-benzoquinone:NADH oxidoreductase activity
hydroxybenzoquinone reductase activity
NADH:2-hydroxy-1,4-benzoquinone oxidoreductase activity
Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+.
TMAO reductase activity
TOR activity
trimethylamine:cytochrome c oxidoreductase activity
Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione.
mycothiol-disulfide reductase activity
mycothiol:NAD(P)+ oxidoreductase activity
Catalysis of the reaction: acetoacetate + coenzyme M + NADP+ = 2-oxopropyl-coenzyme M + CO2 + NADPH.
2-KPCC activity
2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating)
NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase activity
NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase activity
Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor. The reaction occurs in the reverse direction.
acceptor:trichloroethene oxidoreductase (chlorinating)
tetrachloroethene reductase activity
Catalysis of the reaction: (E)-isoeugenol + S-adenosyl-L-methionine = (E)-isomethyleugenol + H+ + S-adenosyl-L-homocysteine.
isoeugenol O-methyltransferase activity
S-adenosyl-L-methionine:isoeugenol O-methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP+.
S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase activity
Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.
3-oxopristanoyl-CoA hydrolase activity
3-oxopristanoyl-CoA thiolase activity
4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA 2-C-4,8,12-trimethyltridecanoyltransferase activity
4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase activity
oxopristanoyl-CoA thiolase activity
peroxisomal 3-oxoacyl coenzyme A thiolase
peroxisome sterol carrier protein thiolase
propionyl-CoA C(2)-trimethyltridecanoyltransferase activity
SCPx
sterol carrier protein
sterol carrier protein X-related thiolase activity
Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.
3-oxopalmitoyl-CoA hydrolase activity
3-oxopalmitoyl-CoA-CoA acetyltransferase activity
myristoyl-CoA C-acetyltransferase activity
myristoyl-CoA:acetyl-CoA C-myristoyltransferase activity
Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.
3-methyl-1-(trihydroxyphenyl)butan-1-one synthase activity
isovaleryl-CoA:malonyl-CoA acyltransferase activity
valerophenone synthase activity
Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H+ + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O.
malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing)
Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine.
acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing)
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H+ + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO2 + 9 CoA + dihydromonacolin L + 6 H2O + 11 NADP+.
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)
Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate.
acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase activity
acetyl coenzyme A:taxa-4(20),11(12)-dien-5-alpha-ol O-acetyl transferase activity
acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase activity
taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase activity
taxadien-5a-ol O-acetyltransferase activity
taxadien-5alpha-ol O-acetyltransferase activity
taxadienol acetyltransferase activity
Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C.
acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase activity
acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase activity
acetyl-CoA:taxan-10beta-ol O-acetyltransferase
Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminoadipate.
acyl-CoA:isopenicillin N N-acyltransferase activity
acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase activity
acyl-coenzyme A:isopenicillin N acyltransferase activity
isopenicillin N:acyl-CoA acyltransferase activity
isopenicillin-N acyltransferase activity
Catalysis of the reaction: acetyl-CoA + 3 H+ + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO2 + 4 CoA + H2O + NADP+.
6-MSAS activity
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)
MSAS activity
Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA.
2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase activity
2a-hydroxytaxane 2-O-benzoyltransferase activity
2alpha-hydroxytaxane 2-O-benzoyltransferase activity
benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase activity
benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase activity
benzoyl-CoA:taxane 2alpha-O-benzoyltransferase activity
Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA.
acetyl-CoA:taxan-10beta-ol O-acetyltransferase
Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H+ + UDP.
UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase activity
Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.
LGTase activity
limonoid UDP-glucosyltransferase activity
uridine diphosphoglucose-limonoid glucosyltransferase activity
Binding to 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid binding
Binding to 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding
Binding to 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding
Catalysis of the reaction: O2 + reduced  + testosterone = 6beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized .
testosterone 6b-hydroxylase activity
The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate.
chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthesis
chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthetic process
chondroitin sulfate B proteoglycan chain elongation
dermatan sulfate proteoglycan anabolism, polysaccharide chain anabolism
dermatan sulfate proteoglycan chain elongation
dermatan sulfate proteoglycan formation, polysaccharide chain biosynthesis
dermatan sulfate proteoglycan formation, polysaccharide chain formation
dermatan sulfate proteoglycan synthesis, polysaccharide chain synthesis
dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis
dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process
The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.
chondroitin sulfate proteoglycan anabolism, polysaccharide chain anabolism
chondroitin sulfate proteoglycan chain elongation
chondroitin sulfate proteoglycan formation, polysaccharide chain biosynthesis
chondroitin sulfate proteoglycan formation, polysaccharide chain formation
chondroitin sulfate proteoglycan synthesis, polysaccharide chain synthesis
chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis
chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process
Binding to 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
3\'-phosphoadenosine 5\'-phosphosulphate binding
3\'-phosphoadenylyl-sulfate binding
adenosine 3\'-phosphate 5\'-phosphosulfate binding
PAPS binding
phosphoadenosine phosphosulfate binding
Catalysis of the reactions: n 3'-phosphoadenylyl sulfate + chondroitin 4'-sulfate = n adenosine 3',5'-bisphosphate + chondroitin 4',6'-bissulfate + n H+, and n 3'-phosphoadenylyl sulfate + dermatan 4'-sulfate = n adenosine 3',5'-bisphosphate + dermatan 4',6'-bissulfate + n H+.
3\'-phosphoadenylyl-sulfate:dermatan 6\'-sulfotransferase activity
GalNAc4S-6ST
N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.
activation of homocysteine metabolic process
positive regulation of Hcy metabolic process
positive regulation of Hcy metabolism
positive regulation of homocysteine metabolism
stimulation of homocysteine metabolic process
up regulation of homocysteine metabolic process
up-regulation of homocysteine metabolic process
upregulation of homocysteine metabolic process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.
down regulation of homocysteine metabolic process
down-regulation of homocysteine metabolic process
downregulation of homocysteine metabolic process
inhibition of homocysteine metabolic process
negative regulation of Hcy metabolic process
negative regulation of Hcy metabolism
negative regulation of homocysteine metabolism
Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.
down regulation of urothelial cell proliferation
down-regulation of urothelial cell proliferation
downregulation of urothelial cell proliferation
inhibition of urothelial cell proliferation
Any process that activates or increases the rate or extent of urothelial cell proliferation.
activation of urothelial cell proliferation
stimulation of urothelial cell proliferation
up regulation of urothelial cell proliferation
up-regulation of urothelial cell proliferation
upregulation of urothelial cell proliferation
Binding to a nuclear androgen receptor.
androgen receptor binding
AR binding
Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction.
down regulation of antiviral response by host
down-regulation of antiviral response by host
downregulation of antiviral response by host
inhibition of antiviral response by host
negative regulation by host of antiviral response
negative regulation of antiviral response by host
Binding to a protein's DNA binding domain (DBD).
DBD binding
Binding to a protein's ligand binding domain (LBD) domain, found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.
ligand binding domain binding
Catalysis of the reaction: benzoylformate = benzaldehyde + CO2.
benzoylformate carboxy-lyase (benzaldehyde-forming)
benzoylformate carboxy-lyase activity
phenylglyoxylate decarboxylase activity
The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.
trichloroethene catabolic process
trichloroethene catabolism
trichloroethylene breakdown
trichloroethylene catabolism
trichloroethylene degradation
Catalysis of the reaction: AH2 + trichloroethene = (Z)-1,2-dichloroethene + A + chloride + H+.
1,1,2-trichloroethene reductive dehalogenase activity
1,1,2-trichloroethylene reductive dehalogenase activity
TCE-reductive dehalogenase activity
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.
proteoglycan sulfate transfer
proteoglycan sulphotransferase activity
Binding to a low-density lipoprotein receptor.
LDL receptor binding
low-density lipoprotein receptor binding
Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.
down regulation of dendrite morphogenesis
down-regulation of dendrite morphogenesis
downregulation of dendrite morphogenesis
inhibition of dendrite morphogenesis
Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl.
2,4,6-TCP reductive dehalogenase activity
2,4,6-trichlorophenol reductive dehalogenase activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).
galactose, glucose uniporter activity
The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.
cocaine breakdown
cocaine catabolism
cocaine degradation
Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).
AGE receptor activity
RAGE activity
Binding to a RAGE receptor, the receptor for advanced glycation end-products.
advanced glycation end-product receptor binding
The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.
mercuric ion (Hg2+) sequestering
mercuric ion (Hg2+) sequestration
mercury (Hg) ion sequestering
mercury (Hg) ion sequestration
mercury (Hg2+) ion retention
mercury (Hg2+) ion storage
retention of mercury (Hg2+) ion
sequestering of mercuric ion (Hg2+)
sequestering of mercury (Hg) ion
sequestration of mercuric ion (Hg2+)
sequestration of mercury (Hg) ion
storage of mercury (Hg2+) ion
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.
5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity
FDTS activity
flavin dependent thymidylate synthase activity
Thy1 activity
ThyX activity
The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.
cocaine anabolism
cocaine biosynthesis
cocaine formation
cocaine synthesis
Binding to diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium.
diazepam binding inhibitor activity
Valium binding
The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.
epothilone anabolism
epothilone biosynthesis
epothilone formation
epothilone synthesis
Binding to a phosphorylated threonine residue within a protein.
phosphothreonine binding
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
lysosomal protein stabilization
positive regulation of protein stability
protein sequestering
protein stabilisation
protein stabilization activity
Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.
peptide antigen stabilization activity
Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.
antifreeze activity
ice crystal binding
ice nucleation activity
ice nucleation inhibitor activity