NothingMuch/GO-Terms huggingface dataset:
Any process that decreases the frequency, rate or extent of non-coding RNA-mediated heterochromatin formation.
negative regulation of chromatin silencing by small RNA
negative regulation of heterochromatin assembly by small RNA
negative regulation of ncRNA-mediated heterochromatin formation
negative regulation of RNAi-mediated heterochromatin assembly
negative regulation of small non-coding RNA-mediated heterochromatin formation
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
regulation of 1,6-beta-glucan biosynthetic process
The directed movement of auxins from outside of a cell into a cell.
auxin influx
The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
atrial cardiomyocyte cell fate commitment
atrial heart muscle cell fate commitment
The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
ventricular cardiomyocyte cell fate commitment
ventricular heart muscle cell fate commitment
The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.
AV node cell development
The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.
AV node cell fate commitment
The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node.
SA node cell commitment
SAN cell commitment
sinus node cell commitment
The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.
SA node cell development
SAN cell development
sinus node cell development
The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.
heart neuron development
The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.
heart neuron fate commitment
Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.
positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter
The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.
lipid tubulation involved in organelle fusion
The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission.
lipid tubulation involved in organelle fission
An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.
hepatobiliary system process
The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.
epicardium development
The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.
fetal lung liquid secretion
The process in which a female gonad is generated and organized.
ovary morphogenesis
Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
positive regulation of peptidoglycan recognition protein signalling pathway
Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
negative regulation of peptidoglycan recognition protein signalling pathway
Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.
positive regulation of prostaglandin secretion during immune response
Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.
epithelial-mesenchymal cell signalling involved in lung development
Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung.
mesothelial-mesenchymal cell signalling involved in early lung development
A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
extracellular matrix organisation involved in endocardium development
The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.
urinary tract segmentation
The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.
endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site
endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site
ER localization involved in ER polarization at cell division site
ER polarization
establishment of endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site
establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site
maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site
transitional endoplasmic reticulum polarization at cell division site
Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
type II terminal button
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.
type Ib terminal button
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.
type Is terminal button
Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
negative regulation of insulin secretion in response to glucose
negative regulation of insulin secretion involved in cellular response to glucose
Any process that decreases the frequency, rate, or extent of heterochromatin formation at silent mating-type cassette.
negative regulation of chromatin silencing at silent mating-type cassette
negative regulation of silent mating-type cassette heterochromatin assembly
Any process that decreases the rate, frequency, or extent of ribosomal DNA heterochromatin formation.
negative regulation of chromatin silencing at rDNA
negative regulation of ribosomal DNA heterochromatin assembly
negative regulation of ribosomal DNA heterochromatin formation
The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.
clathrin sculpted GABA transport vesicle lumen
clathrin sculpted gamma-aminobutyric acid transport vesicle lumen
The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.
clathrin sculpted GABA transport vesicle membrane
clathrin sculpted gamma-aminobutyric acid transport vesicle membrane
The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.
Mullerian duct development
Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.
cell-cell signalling involved in mesonephros development
The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
mesonephric Goormaghtigh proliferation
mesonephric lacis cell proliferation
Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros.
establishment of planar cell polarity involved in mesonephric nephron morphogenesis
The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.
mesonephric glomerular visceral epithelial cell development
The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.
mesonephric glomerular visceral epithelial cell fate commitment
The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.
mesonephros interstitial cell development
The process in which the connecting tubule of the mesonephric nephron acquires its identity.
specification of mesonephric collecting tubule identity
Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis
negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis
Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis
positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.
fibroblast growth factor receptor signalling pathway involved in heart development
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
canonical Wnt receptor signaling pathway involved in heart development
canonical Wnt receptor signalling pathway involved in heart development
canonical Wnt-activated signaling pathway involved in heart development
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
pericardial cell differentiation
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
garland cell differentiation
The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.
Malpighian tubule formation
The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.
optic chiasm development
Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis.
functional luteolysis
The apoptotic process that contributes to luteolysis.
apoptosis involved in luteolysis
structural luteolysis
Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.
negative regulation of testicular vasculature morphogenesis
The closure of the temporary ventral gap in the optic cup that contributes to its shaping.
closure or choriod fissure
Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
epithelial barrier development
establishment of epithelial barrier
skin barrier development
The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.
ICC differentiation
The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.
T-helper follicular cell differentiation
Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H+ + phosphate.
SPA synthase activity
Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
high affinity fructose transmembrane transporter activity
Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).
2\',3\' cyclic GMP-AMP synthase activity
2\',3\' cyclic-GMP-AMP synthase activity
cyclic 2\',3\' GAMP synthase activity
cyclic-GMP-AMP synthase activity
Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.
2\',3\' cGAMP binding
2\',3\' cyclic GAMP binding
2\',3\'-cGAMP binding
2\',3\'-cyclic GAMP binding
2\',5-3\',5\'-cyclic GMP-AMP binding
c binding
cyclic-GMP-AMP binding
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + phosphate(in) = glucose 6-phosphate(in) + phosphate(out).
glucose 6-phosphate:inorganic phosphate antiporter activity
The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.
adrenaline secretion, neurotransmission
The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.
noradrenaline secretion, neurotransmission
Catalysis of the reaction: S-adenosyl-L-methionine + a 3-demethylubiquinol = S-adenosyl-L-homocysteine + a ubiquinol.
2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase
5-demethylubiquinone-10 methyltransferase
5-demethylubiquinone-9 methyltransferase
OMHMB-methyltransferase
S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase
The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.
sympathetic ganglia development
A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.
trigeminal ganglia maturation
The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.
trigeminal ganglia formation
The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.
trigeminal ganglia organization
A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell.
actin filament cable retrograde transport
Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.
cyclin-dependent protein kinase 5 activator activity
Hydrolysis of a ubiquitin unit from a ubiquitinated protein linked via the Lys63 residue of ubiquitin.
K63-specific deubiquitinase activity
Lys63-specific deubiquitinase activity
Catalyzing the reaction: acyl- + S-adenosyl-L-methionine ->  + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone.
autoinducer-1 synthase
The controlled release of orexin from a cell in which orexin acts as a neurotransmitter.
hypocretin secretion, neurotransmission
Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein.
N-terminal propionyltransferase activity
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
importin activity
The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.
glycerol metabolism to DHAP
glycerol metabolism to dihydroxyacetone phosphate
glycerol metabolism to glycerone phosphate
glycerol to DHAP metabolic process
glycerol to dihydroxyacetone phosphate metabolic process
The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.
mannose metabolism to fructose-6-phosphate
The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.
glycolysis from fructose through fructose-6-phosphate
Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.
Fcj1 complex
MINOS complex
mitochondrial contact site and cristae organizing system
MitOS complex
The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.
aortic arch artery morphogenesis
Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.
homocysteine methyltransferase activity
homocysteine transmethylase activity
methylmethionine:homocysteine methyltransferase activity
S-methylmethionine homocysteine transmethylase activity
Binding to a histone H3 in which the lysine residue at position 27 has been modified by trimethylation.
H3-K27me3 modified histone binding
Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y = Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
E2
HECT E3
Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.
alpha-xylosidase
A molecular adaptor that recognizes and binds a histone protein containing a ubiquitination modification and that brings the target protein into contact with another protein to allow those proteins to function in a coordinated way.
ubiquitin modification-dependent histone binding
ubiquitinated histone binding
Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.
E2
Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.
E2
Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y = Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue.
E2
Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue.
E2
Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.
E2
Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y = Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue.
E2