NothingMuch/GO-Terms huggingface dataset:
Enables the transmembrane transfer of a monoatomic cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.
osmolarity-sensing cation channel activity
The clathrin-mediated endocytosis of an extracellular exosome.
clathrin-mediated extracellular exosome endocytosis
exosome related
A transmembrane signaling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation.
CD42
GPIb-IX-V complex
GPIb-V-IX complex
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.
response to immobilization stress combined with water immersion
Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling.
negative regulation of hedgehog target transcription factor
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.
cellular response to astrocyte-derived trophic factor
cellular response to ATF
cellular response to GDNF
A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.
Msd1-Wdr8-Pkl1 complex
The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation at meiotic anaphase I after cohesin is cleaved by separase along the arm regions.
anaphase cohesion protection
protection of centromeric cohesion during meiotic anaphase I
A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.
vacuole and mitochondria patch
vCLAMP
Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide. The primer may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
NTP polymerase activity
poly(A) polymerase activity
polynucleotide adenylyltransferase activity
RNA adenylating enzyme
RNA adenyltransferase activity
RNA adenylyltransferase activity
A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.
actin fusion focus
A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.
response to signal involved in mitotic DNA integrity checkpoint
Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex.
associated with the nuclear pore
Binding to C-rich, single-stranded DNA.
C-rich ssDNA binding
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
cellular response to CDF
cellular response to cholinergic differentiation factor
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins.
cellular response to pregnancy specific glycoprotein
A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.
galactose-containing glycoprotein complex
Haemonchus galactose-containing glycoprotein complex
A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6.
Frizzled-LRP5/6 complex
Fz/Wnt/LRP6 complex
Wnt receptor complex
WNT-FZD-LRP5 complex
Wnt-FZD-LRP5/6 trimeric complex
WNT-FZD-LRP6 complex
Wnt-induced Frizzled-LRP5/6 complex
Wnt.Fz.LRP ternary complex
The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles.
vacuole-endoplasmic reticulum attachment
vacuole-endoplasmic reticulum tethering
vacuole-ER attachment
A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p.
Ubp3-Bre5 ubiquitin protease complex
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins.
response to GHRF
response to GRF
response to growth hormone-releasing factor
response to sermorelin
response to somatocrinin
response to somatoliberin
response to somatorelin
The side of the nuclear pore complex (NPC) that faces the nucleoplasm.
nucleoplasmic side of NPC
nucleoplasmic side of nuclear pore complex
nucleoplasmic side of nucleopore
The side of the nuclear pore complex (NPC) that faces the cytoplasm.
cytoplasmic side of NPC
cytoplasmic side of nuclear pore complex
cytoplasmic side of nucleopore
A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains follicular (FLCN) and either follicular interacting protein 1 (FNIP1) or FNIP2.
BFC complex
FLCN-FNIP1 complex
FLCN-FNIP2 complex
FNIP-Folliculin RagC/D GAP complex
Lst4-Lst7 complex
A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.
Cdc13-Stn1-Ten1 complex
CTC1-OBFC1-TEN1 complex
The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis.
mitotic chromosome condensation at kinetochore
A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma.
cilium pocket collar
flagellar collar
flagellar pocket collar
flagellar pore
flagellum pocket collar
FPC
A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein.
LRP5/6 signalosome
LRP6 signalosome
Wnt signalosome complex
Wnt-LRP5/6 signalosome
The binding activity of a molecule that brings together a proteasome complex and a nuclear inner membrane, to maintain the nuclear membrane localization of the proteasome.
nuclear membrane proteasome adaptor
nuclear membrane proteasome anchor
nuclear membrane proteasome tether
nuclear membrane proteasome tether activity
nuclear membrane-proteasome anchor activity
nuclear membrane-proteasome tether activity
tethering factor for nuclear proteasome
Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde.
RNA N(1)-methyladenosine dioxygenase activity
RNA N1-methyladenosine dioxygenase activity
Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde.
mRNA N(6)-methyladenine demethylase
mRNA N(6)-methyladenosine dioxygenase activity
RNA N6-methyladenosine dioxygenase activity
A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles.
compact nucleolus
NLB
The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein.
aspartyl autophosphorylation
peptidyl-aspartate autophosphorylation
A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate.
kinetochore retrieval
metaphase chromosome retrieval to the spindle pole body
microtubule sliding involved in kinetochore retrieval
microtubule sliding involved in metaphase chromosome retrieval to the spindle pole body
microtubule sliding involved in mitotic metaphase chromosome recapture
microtubule sliding involved in sister kinetochore recapture
sister kinetochore recapture
Binding to the replication fork barrier found in the mating type region of fission yeast.
RTS1 barrier binding
RTS1 element binding
Binds to and stops, prevents or reduces the activity of a ubiquitin ligase.
APC-Cdc20 complex inhibitor activity
mitotic anaphase-promoting complex inhibitor activity
The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments.
IMT
A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways.
NPHP module
The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
eosinocyte homeostasis
eosinophilic granulocyte homeostasis
eosinophilic leucocyte homeostasis
eosinophilic leukocyte homeostasis
The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
basophilic leucocyte homeostasis
The directed movement of a xenobiotic through the blood-brain barrier.
drug transport across blood-brain barrier
Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type.
establishment of blood-retina barrier
establishment of BRB
A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA.
modulation by host of viral protein:RNA interaction
A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor.
modulation by host of viral Tat activity
Binding to a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter.
TAR binding
Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures.
Elastic microfibrillar interface 1 complex
Elastic microfibrillar interface 2 complex
EMILIN-1 complex
EMILIN-2 complex
Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures.
Elastic microfibrillar interface 3 complex
Elastic microfibrillar interface 4 complex
EMILIN-3 complex
EMILIN-4 complex
Multimerin-1 complex
Multimerin-2 complex
p155 complex
Platelet glycoprotein Ia* complex
A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge).
TAN line
The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell.
actin-dependent nuclear movement
A process in which translation initiation is regulated by post-translation modifications of a tRNA molecule.
tRNA demethylation
Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface.
negative regulation of protein localisation at cell surface
negative regulation of protein localization at cell surface
Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface.
positive regulation of protein localisation at cell surface
positive regulation of protein localization at cell surface
Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation.
regulation of adaxial/abaxial pattern specification
Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine.
regulation of arginine anabolism via ornithine
regulation of arginine formation via ornithine
regulation of arginine synthesis via ornithine
Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.
negative regulation of determination of adaxial identity
Any process that activates or increases the frequency, rate or extent of determination of dorsal identity.
positive regulation of determination of adaxial identity
Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.
negative regulation of testicular development
negative regulation of testis development
Any process that activates or increases the frequency, rate or extent of male gonad development.
positive regulation of testicular development
positive regulation of testis development
Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway.
regulation of jasmonic acid mediated signalling pathway
Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.
regulation of proanthocyanidin anabolism
regulation of proanthocyanidin biosynthesis
regulation of proanthocyanidin formation
regulation of proanthocyanidin synthesis
Any process that modulates the frequency, rate or extent of secondary shoot formation.
regulation of auxiliary shoot formation
regulation of axillary shoot formation
regulation of axillary shoot system formation
regulation of shoot branching
Any process that modulates the frequency, rate or extent of trichome morphogenesis.
regulation of trichome cell morphogenesis during differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process.
negative regulation of cortisol anabolism
negative regulation of cortisol biosynthesis
negative regulation of cortisol formation
negative regulation of cortisol synthesis
Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process.
positive regulation of cortisol anabolism
positive regulation of cortisol biosynthesis
positive regulation of cortisol formation
positive regulation of cortisol synthesis
Any process that modulates the frequency, rate or extent of defense response by callose deposition.
regulation of callose deposition during defense response
regulation of callose localization during defense response
Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.
negative regulation of site selection involved in cell cycle cytokinesis
Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.
negative regulation of pancreatic B cell development
negative regulation of pancreatic beta cell development
Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.
positive regulation of pancreatic B cell development
positive regulation of pancreatic beta cell development
Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process.
negative regulation of ascorbate biosynthesis
negative regulation of ascorbate biosynthetic process
negative regulation of L-ascorbic acid anabolism
negative regulation of L-ascorbic acid biosynthesis
negative regulation of L-ascorbic acid formation
negative regulation of L-ascorbic acid synthesis
negative regulation of vitamin C biosynthesis
negative regulation of vitamin C biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.
negative regulation of mesonephric mesenchyme to epithelial transition
Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.
positive regulation of mesonephric mesenchyme to epithelial transition
Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.
positive regulation of non-canonical Wnt signaling pathway
positive regulation of PCP pathway
positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway
positive regulation of Wnt receptor signalling pathway, planar cell polarity pathway
positive regulation of Wnt-activated signaling pathway, planar cell polarity pathway
positive regulation of Wnt-JNK signaling pathway
positive regulation of Wnt-PCP signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.
negative regulation of activation-induced cell death
negative regulation of AICD
negative regulation of macrophage apoptosis
Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.
positive regulation of activation-induced cell death
positive regulation of AICD
positive regulation of macrophage apoptosis
Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.
regulation of endocannabinoid signalling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway.
negative regulation of tyramine signalling pathway
Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway.
positive regulation of tyramine signalling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food.
negative regulation of octopamine signalling pathway involved in response to food
Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food.
positive regulation of octopamine signalling pathway involved in response to food
Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER.
regulation of cis-Golgi to rough endoplasmic reticulum transport
regulation of cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport
regulation of cis-Golgi to rough ER transport
regulation of cis-Golgi to rough ER vesicle-mediated transport
regulation of retrograde (Golgi to ER) transport
regulation of retrograde transport, Golgi to endoplasmic reticulum
regulation of retrograde transport, Golgi to ER
regulation of retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.
negative regulation of deubiquitinase activity
negative regulation of ubiquitin hydrolase activity
negative regulation of UBP
negative regulation of UCH2
Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.
positive regulation of deubiquitinase activity
positive regulation of ubiquitin hydrolase activity
positive regulation of UBP
positive regulation of UCH2
Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.
negative regulation of pro-T lymphocyte differentiation
Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.
positive regulation of pro-T lymphocyte differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process.
negative regulation of androgen anabolism
negative regulation of androgen biosynthesis
negative regulation of androgen formation
negative regulation of androgen synthesis
Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.
positive regulation of progesterone anabolism
positive regulation of progesterone biosynthesis
positive regulation of progesterone formation
positive regulation of progesterone synthesis
Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.
negative regulation of phosphate membrane transport
Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport.
positive regulation of phosphate membrane transport
Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus.
negative regulation of 50S ribosomal subunit export from nucleus
negative regulation of 60S ribosomal subunit export from nucleus
negative regulation of ribosomal large subunit export from cell nucleus
negative regulation of ribosomal large subunit export out of nucleus
negative regulation of ribosomal large subunit transport from nucleus to cytoplasm
negative regulation of ribosomal large subunit-nucleus export
Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.
positive regulation of 50S ribosomal subunit export from nucleus
positive regulation of 60S ribosomal subunit export from nucleus
positive regulation of ribosomal large subunit export from cell nucleus
positive regulation of ribosomal large subunit export out of nucleus
positive regulation of ribosomal large subunit transport from nucleus to cytoplasm
positive regulation of ribosomal large subunit-nucleus export
Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus.
negative regulation of 30S ribosomal subunit export from nucleus
negative regulation of 40S ribosomal subunit export from nucleus
negative regulation of ribosomal small subunit export from cell nucleus
negative regulation of ribosomal small subunit export out of nucleus
negative regulation of ribosomal small subunit transport from nucleus to cytoplasm
negative regulation of ribosomal small subunit-nucleus export