NothingMuch/GO-Terms huggingface dataset:
The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.
natural killer cell granule exocytosis
NK cell degranulation
NK cell granule exocytosis
Any process that modulates the frequency, rate, or extent of natural killer cell degranulation.
regulation of natural killer cell granule exocytosis
regulation of NK cell degranulation
regulation of NK cell granule exocytosis
The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism.
pigment metabolic process during developmental pigmentation
pigment metabolism during developmental pigmentation
The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.
chemotaxis to 3\',5\' cAMP
chemotaxis to 3\',5\'-cAMP
chemotaxis to adenosine 3\',5\'-cyclophosphate
chemotaxis to cyclic AMP
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
response to exogenous double-stranded RNA
response to viral dsRNA
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.
response to double-stranded RNA
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
conjugation tube tip
shmoo tip
The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus.
enucleate RBC differentiation
enucleate red blood cell differentiation
A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.
enucleate RBC maturation
enucleate red blood cell maturation
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds.
nucleate RBC differentiation
nucleate red blood cell differentiation
Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).
catalysis of free radical formation
The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.
CD4-positive, alpha beta T cell development
CD4-positive, alpha beta T cell differentiation
CD4-positive, alpha-beta T lymphocyte differentiation
CD4-positive, alpha-beta T-cell differentiation
CD4-positive, alpha-beta T-lymphocyte differentiation
The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.
positive T lymphocyte selection
positive T-cell selection
positive T-lymphocyte selection
The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.
CD4-positive or CD8-positive, alpha-beta T lymphocyte lineage commitment
CD4-positive or CD8-positive, alpha-beta T-cell lineage commitment
CD4-positive or CD8-positive, alpha-beta T-lymphocyte lineage commitment
CD4-positive/CD8-positive, alpha-beta T cell lineage commitment
Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.
regulation of CD4-positive T lymphocyte differentiation
regulation of CD4-positive T-cell differentiation
regulation of CD4-positive T-lymphocyte differentiation
regulation of CD4-positive, alpha beta T cell development
regulation of CD4-positive, alpha beta T cell differentiation
regulation of CD4-positive, alpha beta T lymphocyte differentiation
regulation of CD4-positive, alpha beta T-cell differentiation
regulation of CD4-positive, alpha beta T-lymphocyte differentiation
Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.
down regulation of CD4-positive, alpha beta T cell differentiation
down-regulation of CD4-positive, alpha beta T cell differentiation
downregulation of CD4-positive, alpha beta T cell differentiation
inhibition of CD4-positive, alpha beta T cell differentiation
negative regulation of CD4-positive T-cell differentiation
negative regulation of CD4-positive T-lymphocyte differentiation
negative regulation of CD4-positive, alpha beta T cell development
negative regulation of CD4-positive, alpha beta T lymphocyte differentiation
negative regulation of CD4-positive, alpha beta T-cell differentiation
negative regulation of CD4-positive, alpha beta T-lymphocyte differentiation
Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.
activation of CD4-positive, alpha beta T cell differentiation
positive regulation of CD4-positive T lymphocyte differentiation
positive regulation of CD4-positive T-cell differentiation
positive regulation of CD4-positive T-lymphocyte differentiation
positive regulation of CD4-positive, alpha beta T cell development
positive regulation of CD4-positive, alpha beta T cell differentiation
positive regulation of CD4-positive, alpha beta T lymphocyte differentiation
positive regulation of CD4-positive, alpha beta T-cell differentiation
positive regulation of CD4-positive, alpha beta T-lymphocyte differentiation
stimulation of CD4-positive, alpha beta T cell differentiation
up regulation of CD4-positive, alpha beta T cell differentiation
up-regulation of CD4-positive, alpha beta T cell differentiation
upregulation of CD4-positive, alpha beta T cell differentiation
The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.
CD4-positive, alpha-beta T lymphocyte lineage commitment
CD4-positive, alpha-beta T-cell lineage commitment
CD4-positive, alpha-beta T-lymphocyte lineage commitment
The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.
CD8-positive, alpha-beta T cell development
CD8-positive, alpha-beta T lymphocyte differentiation
CD8-positive, alpha-beta T-cell differentiation
CD8-positive, alpha-beta T-lymphocyte differentiation
Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.
regulation of CD8-positive T lymphocyte differentiation
regulation of CD8-positive T-cell differentiation
regulation of CD8-positive T-lymphocyte differentiation
regulation of CD8-positive, alpha beta T lymphocyte differentiation
regulation of CD8-positive, alpha beta T-cell differentiation
regulation of CD8-positive, alpha beta T-lymphocyte differentiation
regulation of CD8-positive, alpha-beta T cell development
The process in which a newly activated T cell acquires specialized features of a memory T cell.
memory T cell development
memory T lymphocyte differentiation
memory T-cell differentiation
memory T-lymphocyte differentiation
Any process that modulates the frequency, rate, or extent of memory T cell differentiation.
regulation of memory T cell development
regulation of memory T lymphocyte differentiation
regulation of memory T-cell differentiation
regulation of memory T-lymphocyte differentiation
The process of elimination of immature T cells which react strongly with self-antigens.
negative T lymphocyte selection
negative T-cell selection
negative T-lymphocyte selection
The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.
mycotoxin metabolism
The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.
mycotoxin anabolism
mycotoxin biosynthesis
mycotoxin formation
mycotoxin synthesis
The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus.
mycotoxin breakdown
mycotoxin catabolism
mycotoxin degradation
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
activation of DNA binding
stimulation of DNA binding
up regulation of DNA binding
up-regulation of DNA binding
upregulation of DNA binding
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
down regulation of DNA binding
down-regulation of DNA binding
downregulation of DNA binding
inhibition of DNA binding
The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle.
corticotropin-releasing factor secretion
CRF secretion
CRH secretion
Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion.
regulation of corticotropin-releasing factor secretion
regulation of CRF secretion
regulation of CRH secretion
The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.
hydrocortisone secretion
The series of molecular signals mediated by a steroid hormone binding to a receptor.
steroid hormone mediated signalling
steroid hormone-mediated signaling pathway
The series of molecular signals mediated by the detection of a glucocorticoid hormone.
glucocorticoid mediated signalling
The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
myofiber turnover
Any process that modulates the frequency, rate or extent of MAP kinase activity.
Regulation of MAPK activity
regulation of mitogen activated protein kinase activity
regulation of mitogen-activated protein kinase activity
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
positive regulation of mitogen activated protein kinase activity
positive regulation of mitogen-activated protein kinase activity
stimulation of MAPK activity
up regulation of MAPK activity
up-regulation of MAPK activity
upregulation of MAPK activity
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
down regulation of MAPK activity
down-regulation of MAPK activity
downregulation of MAPK activity
inhibition of MAPK activity
negative regulation of mitogen activated protein kinase activity
negative regulation of mitogen-activated protein kinase activity
Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.
regulation of MAP kinase cascade
regulation of MAP kinase kinase kinase cascade
regulation of MAPKKK cascade
regulation of mitogen activated protein kinase cascade
regulation of mitogen activated protein kinase kinase kinase cascade
regulation of mitogen-activated protein kinase cascade
regulation of mitogen-activated protein kinase kinase kinase cascade
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
down regulation of MAPK cascade
down regulation of MAPKKK cascade
down-regulation of MAPK cascade
down-regulation of MAPKKK cascade
downregulation of MAPK cascade
downregulation of MAPKKK cascade
inhibition of MAPK cascade
inhibition of MAPKKK cascade
negative regulation of MAP kinase cascade
negative regulation of MAP kinase kinase kinase cascade
negative regulation of MAPKKK cascade
negative regulation of mitogen activated protein kinase cascade
negative regulation of mitogen activated protein kinase kinase kinase cascade
negative regulation of mitogen-activated protein kinase cascade
negative regulation of mitogen-activated protein kinase kinase kinase cascade
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
activation of MAPK cascade
activation of MAPKKK cascade
positive regulation of MAP kinase cascade
positive regulation of MAP kinase kinase kinase cascade
positive regulation of MAPKKK cascade
positive regulation of mitogen activated protein kinase kinase kinase cascade
positive regulation of mitogen-activated protein kinase cascade
positive regulation of mitogen-activated protein kinase kinase kinase cascade
stimulation of MAPK cascade
stimulation of MAPKKK cascade
up regulation of MAPKKK cascade
up-regulation of MAPK cascade
up-regulation of MAPKKK cascade
upregulation of MAPK cascade
upregulation of MAPKKK cascade
Any process that activates or increase the rate of skeletal muscle regeneration.
activation of skeletal muscle regeneration
stimulation of skeletal muscle regeneration
up regulation of skeletal muscle regeneration
up-regulation of skeletal muscle regeneration
upregulation of skeletal muscle regeneration
Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.
down regulation of skeletal muscle regeneration
down-regulation of skeletal muscle regeneration
downregulation of skeletal muscle regeneration
inhibition of skeletal muscle regeneration
The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
urea breakdown
urea catabolism
urea decomposition
urea degradation
The chemical reactions and pathways involving anthranilate (2-aminobenzoate).
2-aminobenzoate metabolic process
2-aminobenzoate metabolism
anthranilate metabolism
anthranilic acid metabolic process
anthranilic acid metabolism
ortho-aminobenzoic acid metabolic process
ortho-aminobenzoic acid metabolism
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
down regulation of transcription factor activity
down-regulation of transcription factor activity
downregulation of transcription factor activity
inhibition of transcription factor activity
negative regulation of androgen receptor activity
negative regulation of DNA binding transcription factor activity
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of thyroid hormone receptor activity
negative regulation of transcription factor activity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
response to peptide hormone stimulus
response to polypeptide hormone stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.
response to corticoliberin stimulus
response to corticotropin-releasing factor stimulus
response to corticotropin-releasing hormone stimulus
response to CRF stimulus
response to CRH stimulus
The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
keto acid metabolic process
keto acid metabolism
ketoacid metabolic process
ketoacid metabolism
oxo acid metabolic process
oxo acid metabolism
oxoacid metabolism
The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH.
3-oxobutanoate metabolic process
3-oxobutanoate metabolism
3-oxobutanoic acid metabolic process
3-oxobutanoic acid metabolism
acetoacetate metabolic process
acetoacetate metabolism
acetoacetic acid metabolism
beta ketobutyric acid metabolic process
beta ketobutyric acid metabolism
beta-ketobutyric acid metabolic process
beta-ketobutyric acid metabolism
diacetic acid metabolic process
diacetic acid metabolism
The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells.
alkane metabolism
The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.
alkane anabolism
alkane biosynthesis
alkane formation
alkane synthesis
The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.
alkane breakdown
alkane catabolism
alkane degradation
The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells.
alkene metabolism
The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
alkene anabolism
alkene biosynthesis
alkene formation
alkene synthesis
The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
alkene breakdown
alkene catabolism
alkene degradation
The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells.
alkyne metabolism
The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.
alkyne breakdown
alkyne catabolism
alkyne degradation
Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
regulation of secondary metabolism
Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis.
regulation of pentose phosphate pathway
regulation of pentose phosphate shunt
regulation of pentose-phosphate pathway
The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.
F-type ATPase complex assembly
Any process that modulates the rate of an ATP-dependent activity.
regulation of adenosinetriphosphatase activity
regulation of ATPase activity
The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.
pigment metabolic process during pigmentation
pigment metabolism during pigmentation
The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment.
pigment metabolic process during pigment accumulation
pigment metabolism during pigment accumulation
The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.
pigment accumulation in response to external stimulus
The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.
pigment biosynthetic process during pigment accumulation
The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.
organismal pigment accumulation
An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway.
AKT signal transduction
AKT signaling
AKT signaling cascade
AKT signalling cascade
phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction
PI3K-PKB/Akt pathway
PI3K/Akt signal transduction
PI3K/PKB signal transduction
PKB signal transduction
PKB signaling
PKB signaling cascade
PKB signalling cascade
protein kinase B signal transduction
protein kinase B signaling
protein kinase B signaling cascade
protein kinase B signalling cascade
A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides.
phage terminase complex
virus terminase complex
The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.
anchoring
membrane-membrane adaptor activity
protein membrane adaptor
protein membrane adaptor activity
protein membrane anchor
A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
muscle plasticity
Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.
skeletal muscle plasticity
Any process that modulates the frequency, rate or extent of muscle adaptation.
regulation of muscle plasticity
Any process that modulates the frequency, rate or extent of JUN kinase activity.
regulation of JUNK activity
Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
regulation of p53 induced by DNA damage response
Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
activation of DNA damage response, signal transduction by p53 class mediator
positive regulation of p53 induced by DNA damage response
stimulation of DNA damage response, signal transduction by p53 class mediator
up regulation of DNA damage response, signal transduction by p53 class mediator
up-regulation of DNA damage response, signal transduction by p53 class mediator
upregulation of DNA damage response, signal transduction by p53 class mediator