NothingMuch/GO-Terms huggingface dataset:
The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.
antigen presentation, lipid antigen
lipid antigen processing and presentation via MHC class Ib
The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
PDGF receptor signaling pathway
PDGF receptor signalling pathway
PDGFR signaling pathway
The series of molecular signals initiated by a ligand binding to an insulin-like growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
IGF receptor signaling pathway
IGF receptor signalling pathway
The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
VEGF receptor signaling pathway
VEGF receptor signalling pathway
VEGFR signaling pathway
The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
TrkA signaling pathway
TrkB signaling pathway
TrkC signaling pathway
tropomyosin-receptor-kinase signaling
The series of molecular signals initiated by a ligand binding to a hepatocyte growth factor receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
HGF receptor signaling pathway
HGF receptor signalling pathway
Met signaling pathway
The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Eph receptor signaling pathway
Eph receptor signalling pathway
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same cell that expresses the receptor. Ligands may also be expressed at the plasma membrane of an adjacent cell (e.g. Notch ligands) or be secreted and diffuse extracellularly from their point of origin to the receiving cell (e.g. interleukins).
receptor agonist activity
signaling molecule
signaling receptor ligand activity
The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
receptor ligand activity
Binding to a CCR chemokine receptor.
beta chemokine receptor binding
beta chemokine receptor ligand
CCR chemokine receptor ligand
Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
regulation of melanin anabolism
regulation of melanin biosynthesis
regulation of melanin formation
regulation of melanin synthesis
Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
regulation of nuclear mRNA splicing via U2-type spliceosome
regulation of nuclear mRNA splicing, via spliceosome
regulation of pre-mRNA splicing
Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
down regulation of nuclear mRNA splicing via U2-type spliceosome
down regulation of nuclear mRNA splicing, via spliceosome
down-regulation of nuclear mRNA splicing via U2-type spliceosome
down-regulation of nuclear mRNA splicing, via spliceosome
downregulation of nuclear mRNA splicing via U2-type spliceosome
downregulation of nuclear mRNA splicing, via spliceosome
inhibition of nuclear mRNA splicing via U2-type spliceosome
inhibition of nuclear mRNA splicing, via spliceosome
negative regulation of nuclear mRNA splicing via U2-type spliceosome
negative regulation of nuclear mRNA splicing, via spliceosome
negative regulation of pre-mRNA splicing
Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
activation of nuclear mRNA splicing via U2-type spliceosome
activation of nuclear mRNA splicing, via spliceosome
positive regulation of nuclear mRNA splicing via U2-type spliceosome
positive regulation of nuclear mRNA splicing, via spliceosome
positive regulation of pre-mRNA splicing
stimulation of nuclear mRNA splicing via U2-type spliceosome
stimulation of nuclear mRNA splicing, via spliceosome
up regulation of nuclear mRNA splicing via U2-type spliceosome
up regulation of nuclear mRNA splicing, via spliceosome
up-regulation of nuclear mRNA splicing via U2-type spliceosome
up-regulation of nuclear mRNA splicing, via spliceosome
upregulation of nuclear mRNA splicing via U2-type spliceosome
upregulation of nuclear mRNA splicing, via spliceosome
Binding to a simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins.
polygalacturonide binding
The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.
haem O metabolic process
haem O metabolism
heme O metabolism
Binding to ubiquinone, a quinone derivative with a tail of isoprene units.
coenzyme Q binding
coenzyme Q6 binding
The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
adhesion plaque assembly
focal adhesion formation
The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster.
male courtship behavior, wing extension
male courtship behaviour, veined wing extension
male courtship behaviour, wing extension
The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
pigmentation during development
Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
regulation of pigmentation during development
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
down regulation of eye pigmentation
down-regulation of eye pigmentation
downregulation of eye pigmentation
inhibition of eye pigmentation
Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
activation of eye pigmentation
stimulation of eye pigmentation
up regulation of eye pigmentation
up-regulation of eye pigmentation
upregulation of eye pigmentation
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
down regulation of cuticle pigmentation
down-regulation of cuticle pigmentation
downregulation of cuticle pigmentation
inhibition of cuticle pigmentation
Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
activation of cuticle pigmentation
stimulation of cuticle pigmentation
up regulation of cuticle pigmentation
up-regulation of cuticle pigmentation
upregulation of cuticle pigmentation
Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster.
adult cuticle pigmentation
Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
down regulation of developmental pigmentation
down-regulation of developmental pigmentation
downregulation of developmental pigmentation
inhibition of pigmentation
Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
activation of developmental pigmentation
stimulation of developmental pigmentation
up regulation of developmental pigmentation
up-regulation of developmental pigmentation
upregulation of developmental pigmentation
A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
autophagic death
autosis
programmed cell death by autophagy
programmed cell death by macroautophagy
type II programmed cell death
The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
somatic stem cell renewal
The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.
male germ-line stem cell renewal
Formation of a group of interconnected cells derived from a single gonial founder cell.
germline cyst formation
Formation of a group of interconnected cells derived from a single female gonial founder cell.
female germline cyst formation
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
activation of fibroblast proliferation
stimulation of fibroblast proliferation
up regulation of fibroblast proliferation
up-regulation of fibroblast proliferation
upregulation of fibroblast proliferation
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
down regulation of fibroblast proliferation
down-regulation of fibroblast proliferation
downregulation of fibroblast proliferation
inhibition of fibroblast proliferation
The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.
mammalian oogenesis stage 3
The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus.
mammalian oogenesis stage 4
The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.
mammalian oogenesis stage 5
The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration.
mammalian oogenesis stage 6
The stage in oogenesis when the antral spaces become distinct and the first polar body forms.
mammalian oogenesis stage 7
The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.
mammalian oogenesis stage 8
The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
Golgi-derived vesicle transport
The evagination of the Golgi membrane, resulting in formation of a vesicle.
dictyosome vesicle budding
Golgi-derived vesicle budding
The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
dictyosome vesicle targeting
Golgi vesicle targeting
vesicle targeting, to, from or within dictyosome
The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles.
dictyosome transport vesicle coating
The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
plasma membrane to endosome targeting
The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
clathrin coating of Golgi-derived vesicle
The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome.
trans-Golgi to endosome targeting
The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.
inter-Golgi cisterna targeting
The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
COPI coating of Golgi-derived vesicle
COPI vesicle coating
The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER.
cis-Golgi to rough endoplasmic reticulum targeting
cis-Golgi to rough ER targeting
vesicle targeting, cis-Golgi to rough ER
The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi.
rough endoplasmic reticulum to cis-Golgi targeting
rough ER to cis-Golgi targeting
vesicle targeting, rough endoplasmic reticulum to cis-Golgi
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
COPII coating of ER-derived vesicle
COPII vesicle coat assembly
COPII vesicle coat formation
The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.
dictyosome vesicle fusion to target membrane
Golgi-derived vesicle fusion to target membrane
The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.
inter-Golgi cisterna transport
The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana.
gametogenesis
The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes.
plant spore formation
Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.
down regulation of telomeric recombination at telomere
down-regulation of telomeric recombination at telomere
downregulation of telomeric recombination at telomere
inhibition of telomeric recombination at telomere
negative regulation of telomeric recombination at telomere
suppression of telomeric recombination at telomere
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
sperm activation
The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
adrenaline transport
The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.
adrenaline secretion
The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.
noradrenaline secretion
Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
regulation of receptor mediated endocytosis
Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
activation of receptor mediated endocytosis
positive regulation of receptor mediated endocytosis
stimulation of receptor mediated endocytosis
up regulation of receptor mediated endocytosis
up-regulation of receptor mediated endocytosis
upregulation of receptor mediated endocytosis
Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
down regulation of receptor mediated endocytosis
down-regulation of receptor mediated endocytosis
downregulation of receptor mediated endocytosis
inhibition of receptor mediated endocytosis
negative regulation of receptor mediated endocytosis
Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.
determination of adaxial/abaxial asymmetry
determination of dorsal-ventral asymmetry
determination of dorsoventral asymmetry
Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
determination of adaxial identity
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
physiological response to pain
Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
behavioural response to pain
The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.
clathrin cage assembly
The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.
vesicle to membrane docking
The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.
vesicle fusion with ER
The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
alveolarization
alveologenesis
The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.
class switch recombination to IgE isotypes
class switching to IgE isotypes
isotype switch recombination to IgE isotypes
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.
class switching to IgA isotypes
isotype switch recombination to IgA isotypes
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.
class switching to IgG isotypes
isotype switch recombination to IgG isotypes
The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.
class switching to IgD isotypes
isotype switch recombination to IgD isotypes
Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.
regulation of class switch recombination to IgE isotypes
regulation of class switching to IgE isotypes
regulation of isotype switch recombination to IgE isotypes
Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.
activation of isotype switching to IgE isotypes
positive regulation of class switch recombination to IgE isotypes
positive regulation of class switching to IgE isotypes
positive regulation of isotype switch recombination to IgE isotypes
stimulation of isotype switching to IgE isotypes
up regulation of isotype switching to IgE isotypes
up-regulation of isotype switching to IgE isotypes
upregulation of isotype switching to IgE isotypes
Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.
regulation of class switch recombination to IgA isotypes
regulation of class switching to IgA isotypes
regulation of isotype switch recombination to IgA isotypes
Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.
regulation of class switch recombination to IgD isotypes
regulation of class switching to IgD isotypes
regulation of isotype switch recombination to IgD isotypes
Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
regulation of class switch recombination to IgG isotypes
regulation of class switching to IgG isotypes
regulation of isotype switch recombination to IgG isotypes
Any process that establishes the spatial arrangement of mitochondria between and within cells.
distribution of mitochondria
mitochondrial distribution
positioning of mitochondria
The partitioning of Golgi apparatus between daughter cells at cell division.
Golgi apparatus inheritance
Golgi division
Golgi partitioning
The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
conidia biosynthesis
conidia formation
The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell.
axial mesoderm cell differentiation
The process in which a cell becomes committed to become an axial mesoderm cell.
axial mesoderm cell fate commitment
The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
axial mesoderm cell fate determination
The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
axial mesoderm cell fate specification
The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
mesoderm cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.
down regulation of mesodermal cell fate determination
down-regulation of mesodermal cell fate determination
downregulation of mesodermal cell fate determination
inhibition of mesodermal cell fate determination