NothingMuch/GO-Terms huggingface dataset:
Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.
trans-synaptic signaling by brain-derived neurotrophic factor
Development of a plant organ, a multi-tissue plant structure that forms a functional unit.
development of a plant organ
The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
maintenance of mitotic sister chromatin cohesion at telomere
maintenance of sister chromatin cohesion at telomere at mitosis
maintenance of telomeric mitotic sister chromatin cohesion
The cell cycle process in which telomeres of sister chromatids are joined during mitosis.
mitotic sister chromatid cohesion at telomere
sister chromatid cohesion at telomere at mitosis
telomeric mitotic sister chromatin cohesion
The lipid bilayer surrounding an exocytic vesicle.
secretory vesicle membrane
The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations.
regulation of cytosolic calcium ion concentration by calcium ion buffering
A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
fibril
The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.
cytoskeletal fiber-based vesicle localization
vesicle cytoskeletal transport
The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.
dense core vesicle cytoskeletal trafficking
Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.
region of cytosol
The series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).
postsynaptic signaling to nucleus
Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
G-protein coupled neurotransmitter receptor activity
A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane.
G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential
The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.
synaptic vesicle processing via endosome
The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.
extra-synaptic extracellular matrix
A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds.
synaptic maintenance
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
synapse adhesion between pre- and post-synapse  syngo_official_label
Any process that modifies the structure/morphology of a synapse.
synapse remodelling
The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.
postsynaptic process involved in chemical synaptic transmission  syngo_official_label
Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol.
neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels  syngo_official_label
The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol.
inorganic ion import into cell
A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall.
protein targeting to spore cell wall
Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.
heart repolarization
regulation of cardiac muscle cell repolarization
regulation of cardiomyocyte membrane repolarization
A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses.
postsynaptic density of inhibitory synapse
A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density).
protein localisation in postsynaptic specialization membrane
The directed movement of proteins along microtubules in neuron projections.
axonal protein transport
The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.
anterograde axon cargo transport
A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
neurotransmitter receptor localisation in postsynaptic specialization membrane
The complete extent of cell cortex that underlies some some region of the plasma membrane.
perimembrane region
Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry.
ficolin granule
ficolin-1 rich granule
An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
ubiquitinyl hydrolase activity
The reorganization or renovation of existing pulmonary blood vessels.
pulmonary blood vessel remodelling
Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.
regulation of late replication origin firing
A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis.
nuclear membrane organization involved in mitotic nuclear division
A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.
chaperone complex
Catalysis of the reaction: a fatty aldehyde + H2O + NAD+ = a fatty acid + 2 H+ + NADH.
fatty aldehyde dehydrogenase activity
Any process that modulates the frequency, rate or extent of vesicle docking.
regulation of vesicle to membrane docking
Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
transfer ribonucleate pseudouridine synthetase activity
transfer RNA pseudouridine synthetase activity
tRNA-pseudouridine synthase activity
tRNA-uridine isomerase activity
tRNA-uridine uracilmutase activity
A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex.
SUMO transferase complex
SUMO-protein ligase complex
Sumoylation complex
Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway
Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway
Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.
negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway
The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.
CIT
The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group.
pyocyanin biosynthetic process
Binding to and responding, e.g. by conformational change, to changes in the cellular level of a lipid.
lipid sensing activity
The directional movement of a symbiont from one host cell to another.
cell-to-cell migration in host
symbiont-mediated dissemination across host cells
Bridging together two regions of a DNA molecule.
double-stranded DNA bridging
dsDNA bridging
Any process that modulates the frequency, rate or extent of the UDP-N_acetylglucosamine biosynthetic process.
regulation of UDP-GlcNAc biosynthetic process
regulation of UDP-N-acetylglucosamine anabolism
regulation of UDP-N-acetylglucosamine biosynthesis
regulation of UDP-N-acetylglucosamine formation
regulation of UDP-N-acetylglucosamine synthesis
The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.
beta-1,2-mannan metabolic process
mannogen metabolism
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein-serine kinase activity
The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.
cap-independent translational initiation of circRNA
Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway
Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.
sexual differentiation
Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.
regulation of mitotic telomere clustering during interphase
A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
cellular anatomical entity
Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.
intermembrane lipid transfer activity
lipid carrier activity
Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
intermembrane phospholipid transfer activity
phospholipid carrier activity
Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
intermembrane sterol transfer activity
sterol carrier activity
Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
intermembrane sphingolipid transfer activity
sphingolipid carrier activity
Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
ceramide carrier activity
ceramide transporter activity
intermembrane ceramide transfer activity
Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
eupodium
Migration of ingested material along the length of the small intestine.
small bowel transit
small intestine transit
Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.
regulation of small bowel transit
regulation of small intestine transit
Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
regulation of small bowel emptying
regulation of small intestine emptying
A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach.
antrum smooth muscle contraction
The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis.
blood vessel anastomosis
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network.
cell adhesion involved in blood vessel anastomosis
cell adhesion involved in vascular anastomosis
The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope.
mitotic telomere clustering during interphase
Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor signaling pathway.
regulation of ecdysone receptor-mediated signaling pathway
Any process that modulates the frequency, rate or extent of cold-induced thermogenesis.
regulation of CIT
Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin.
negative regulation of protein localisation to chromatin
Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.
positive regulation of protein localisation to chromatin
Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.
down regulation of RNA 3\'-end formation by RNA polymerase II
down regulation of RNA polymerase II transcription termination
down regulation of RNA polymerase II transcription termination factor activity
down regulation of termination of RNA polymerase II transcription
down regulation of transcription termination from Pol II promoter
down regulation of transcription termination from RNA polymerase II promoter
down-regulation of RNA 3\'-end formation by RNA polymerase II
down-regulation of RNA polymerase II transcription termination
down-regulation of RNA polymerase II transcription termination factor activity
down-regulation of termination of RNA polymerase II transcription
down-regulation of transcription termination from Pol II promoter
down-regulation of transcription termination from RNA polymerase II promoter
downregulation of RNA 3\'-end formation by RNA polymerase II
downregulation of RNA polymerase II transcription termination
downregulation of RNA polymerase II transcription termination factor activity
downregulation of termination of RNA polymerase II transcription
downregulation of transcription termination from Pol II promoter
downregulation of transcription termination from RNA polymerase II promoter
negative regulation of RNA 3\'-end formation by RNA polymerase II
negative regulation of RNA polymerase II transcription termination
negative regulation of RNA polymerase II transcription termination factor activity
negative regulation of transcription termination from Pol II promoter
negative regulation of transcription termination from RNA polymerase II promoter
repression of RNA 3\'-end formation by RNA polymerase II
repression of RNA polymerase II transcription termination
repression of RNA polymerase II transcription termination factor activity
repression of termination of RNA polymerase II transcription
repression of transcription termination from Pol II promoter
repression of transcription termination from RNA polymerase II promoter
A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
occluding cell junction assembly
occluding junction assembly
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
occluding cell junction organization
occluding junction organization
Any process that modulates the frequency, rate or extent of histidine biosynthetic process.
regulation of histidine anabolism
regulation of histidine biosynthesis
regulation of histidine formation
regulation of histidine synthesis
Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.
acyl binding
acyl-coenzyme A binding
Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane.
regulation of N-terminal signal peptide-independent translocation into the ER
regulation of posttranslational endoplasmic reticulum membrane protein translocation
regulation of posttranslational protein targeting to membrane, translocation
regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation
The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.
terminal alkyne substituted compound anabolic process
terminal alkyne substituted compound anabolism
terminal alkyne substituted compound biosynthesis
terminal alkyne substituted compound biosynthetic process
terminal alkyne substituted compound synthesis
Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.
2-iminobutanoate deaminase
2-iminopropanoate deaminase
enamine/imine deaminase
imine intermediate deaminase activity   {comment=EC:3.5.99.10}
The chemical reactions and pathways involving a terminal acetylenic compound, involving a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.
terminal alkyne substituted compound metabolic process
terminal alkyne substituted compound metabolism
The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
alkyne substituted compound metabolic process
alkyne substituted compound metabolism
The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
alkyne substituted compound anabolic process
alkyne substituted compound anabolism
alkyne substituted compound biosynthesis
alkyne substituted compound biosynthetic process
alkyne substituted compound synthesis
The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
alkyne substituted compound breakdown
alkyne substituted compound catabolic process
alkyne substituted compound catabolism
alkyne substituted compound degradation
Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced  = an omega-hydroxy fatty acid + H+ + H2O + oxidized .
omega-hydroxylase activity
The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only.
hydrocarbon anabolism
hydrocarbon biosynthesis
hydrocarbon formation
hydrocarbon synthesis
The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.
hydrocarbon metabolism
The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.
hydrocarbon breakdown
hydrocarbon catabolism
hydrocarbon degradation
The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
alkene substituted compound metabolic process
alkene substituted compound metabolism
The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
alkene substituted compound anabolic process
alkene substituted compound anabolism
alkene substituted compound biosynthesis
alkene substituted compound biosynthetic process
alkene substituted compound synthesis
The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
alkene substituted compound breakdown
alkene substituted compound catabolic process
alkene substituted compound catabolism
alkene substituted compound degradation
The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products.
cerebrum blood circulation
telencephelon blood circulation
Any process that modulates the frequency, rate or extent of cerebral blood circulation.
regulation of cerebrum blood circulation
regulation of telencephalon blood circulation
Catalysis of the reaction: (L-lysyl- + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-.
peptide lactyltransferase (CoA dependent) activity
peptide lactyltransferase activity
peptide lactyltransferase activity (CoA-dependent)
The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is most proximal to the base of the cilium. Radial spoke 1 (RS1), similarly to radial spoke 2, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and 4) an orthogonal head. The base of RS1 is connected to the tail of the inner dynein arm a/d.
RS1