NothingMuch/GO-Terms huggingface dataset:
Any process that increases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.
positive regulation of gamma-interferon-mediated signaling pathway
positive regulation of immune interferon-mediated signaling pathway
positive regulation of interferon-gamma-mediated signaling pathway
positive regulation of interferon-gamma-mediated signalling pathway
positive regulation of type II IFN-mediated pathway
Any process that decreases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.
negative regulation of gamma-interferon-mediated signaling pathway
negative regulation of immune interferon-mediated signaling pathway
negative regulation of interferon-gamma-mediated signaling pathway
negative regulation of interferon-gamma-mediated signalling pathway
negative regulation of type II IFN-mediated signaling pathway
Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway.
negative regulation of type I interferon-mediated signalling pathway
Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway.
positive regulation of type I interferon-mediated signalling pathway
The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.
liver trabecula biogenesis
liver trabeculation
The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.
spleen trabecula biogenesis
spleen trabeculation
The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.
cardiac trabecula formation
cardiac trabeculation
heart trabecula biogenesis
heart trabeculation
Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle.
negative regulation of leucine uptake in response to ammonium ion
The process in which the frontal suture is generated and organized.
interfrontal suture morphogenesis
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.
atrial depolarization
electrocardiogram PR interval
regulation of atrial cardiac muscle cell depolarization
regulation of atrial cardiomyocyte membrane depolarization
Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.
electrocardiogram QRS complex
regulation of ventricular cardiomyocyte membrane depolarization
ventricular depolarization
Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding.
positive regulation of telomeric ssDNA binding
The assembly of a synapse within a target tissue in which a nerve is invading.
synapse biogenesis involved in innervation
synaptogenesis involved in innervation
A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.
fertilization membrane
A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.
fertilization membrane
Any process that increases the rate, frequency or extent of SMAD protein signal transduction.
positive regulation of SMAD protein import into nucleus
positive regulation of SMAD protein nuclear translocation
Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway.
negative regulation of SMAD protein import into nucleus
negative regulation of SMAD protein nuclear translocation
The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
JAK-STAT cascade involved in growth hormone signalling pathway
Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
positive regulation of growth hormone receptor signalling pathway
Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
negative regulation of growth hormone receptor signalling pathway
The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.
pulmonary vasculature development
The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.
pulmonary connective tissue development
Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.
reactivation of meiosis after fertilization
resumption of meiosis involved in egg activation
Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.
positive regulation of cortical granule exocytosis by elevation of cytosolic calcium ion concentration
A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.
cortical vesicle
The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.
positive regulation of sperm motility involved in capacitation
The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.
protein localisation involved in acrosome reaction
The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.
Clara cell differentiation
The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.
perpendicular dichotomous subdivision of terminal units involved in lung branching morphogenesis
Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.
mesenchymal-endodermal cell signalling involved in lung induction
The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.
hedgehog signaling pathway involved in lung development
hh signaling pathway involved in lung development
smoothened signalling pathway involved in lung development
The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.
epidermal growth factor receptor signalling pathway involved in lung development
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.
pulmonary basal cell differentiation
The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.
membranous pneumocyte differentiation
small alveolar cell differentiation
squamous alveolar cell differentiation
The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.
granular pneumocyte differentiation
great alveolar cell differentiation
large alveolar cell differentiation
Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate.
mesenchymal-epithelial cell signalling involved in prostate induction
The process in which a prostate epithelial cord bifurcates at its end.
prostate epithelial cord bifurcation
Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
negative regulation of D-loop biosynthesis
negative regulation of D-loop formation
negative regulation of Rad51-mediated strand invasion
Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
positive regulation of necroptosis
Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
negative regulation of necroptosis
The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.
pulmonary venous blood vessel morphogenesis
Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
regulation of actin cortical patch localisation
Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
positive regulation of (PG)H synthase activity
positive regulation of fatty acid cyclooxygenase activity
positive regulation of PG synthetase activity
positive regulation of prostaglandin synthetase activity
A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
multicellular organismal iron ion homeostasis
The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.
chondrocyte progenitor cell differentiation
The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
fibroblast growth factor receptor signalling pathway involved in mammary gland specification
The process in which the terminal end of a mammary duct bifurcates.
primary mammary duct branching
The process in which a branch forms along the side of a mammary duct.
mammary gland duct secondary branching
Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.
milk duct cavitation
The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.
mammary gland mesenchymal cell differentiation
The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.
mammary gland sprout formation
Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.
positive regulation of mammary placode formation by mesenchymal-epithelial signalling
Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.
regulation of cullin deneddylation
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
negative regulation of 1,3-beta-D-glucan biosynthetic process
The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.
positive regulation of lactation by mesenchymal-epithelial cell signalling
Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.
positive regulation of salivary gland formation by mesenchymal-epithelial signalling
Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.
positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signaling
positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signalling
The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.
epithelial cell differentiation involved in mammary gland sprout morphogenesis
Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell.
regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signalling
Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.
regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signalling
Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.
apoptosis involved in salivary gland cavitation
Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalling
Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland.
regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signalling
Any process that mediates the transfer of information from one cell to another.
cell-cell signalling involved in placenta development
The process in which a ureteric bud bifurcates at its end.
bifid subdivision of terminal units involved in ureteric bud branching
Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signalling
Binds to and stops, prevents or reduces the activity of deoxyribonuclease.
DNase inhibitor activity
The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.
spongiotrophoblast cell differentiation
Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.
regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress
regulation of eIF2 alpha phosphorylation by ER stress
regulation of ER stress-induced eIF2 alpha phosphorylation
Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.
regulation of eIF2 alpha phosphorylation by double-stranded RNA
regulation of eIF2 alpha phosphorylation by PKR
The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
prostate gland epithelial cell development
The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
mammary gland branching involved in puberty
Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.
cell-cell signalling involved in mammary gland development
Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.
negative regulation of androgen receptor signalling pathway
The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.
mesenchymal hedgehog signaling pathway involved in prostate gland development
mesenchymal hh signaling pathway involved in prostate gland development
mesenchymal smoothened signalling pathway involved in prostate gland development
Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.
positive regulation of posterior neural plate formation by FGF receptor signaling pathway
positive regulation of posterior neural plate formation by fibroblast growth factor receptor signalling pathway
Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.
epiblast cell-extraembryonic ectoderm cell signalling involved in anterior/posterior axis specification
Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.
orthodenticle mRNA localisation
Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.
anterior mRNA localisation involved in anterior/posterior axis specification
Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.
posterior mRNA localisation involved in anterior/posterior axis specification
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.
rXCI
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genomic imprinting.
inactivation of paternal X chromosome by genetic imprinting
iXCI
Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.
ciliary receptor clustering involved in hedgehog signaling pathway
ciliary receptor clustering involved in hh signaling pathway
ciliary receptor clustering involved in smoothened signalling pathway
The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo.
oral/aboral axis determination
The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.
vascular endothelial growth factor receptor signalling pathway involved in lymphatic endothelial cell fate commitment
The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.
Notch signalling pathway involved in arterial endothelial cell fate commitment
The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.
patterning of lymph vessels
Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
establishment of glial BBB
establishment of glial blood/brain barrier
The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.
membrane trafficking involved in floral organ shedding
A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion.
basal lamina disassembly involved in semicircular canal fusion
Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.
clearance of cells from fusion plate by apoptosis