NothingMuch/GO-Terms huggingface dataset:
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
down regulation of protein modification
down-regulation of protein modification
downregulation of protein modification
inhibition of protein modification
Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
activation of protein modification
stimulation of protein modification
up regulation of protein modification
up-regulation of protein modification
upregulation of protein modification
The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.
oxylipin metabolism
A vesicle found in the cytoplasm of a cell.
cytoplasmic membrane bounded vesicle
cytoplasmic membrane-enclosed vesicle
cytoplasmic, membrane-bounded vesicle
An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations.
gas vacuole
A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule.
NAT complex
Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
activation of mRNA 3\'-end processing
stimulation of mRNA 3\'-end processing
up regulation of mRNA 3\'-end processing
up-regulation of mRNA 3\'-end processing
upregulation of mRNA 3\'-end processing
A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.
fast-twitch skeletal fiber contraction
fast-twitch skeletal fibre contraction
fast-twitch skeletal muscle fibre contraction
fast-twitch skeletal myofiber contraction
fast-twitch skeletal myofibre contraction
A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.
slow-twitch skeletal muscle fibre contraction
Any process that modulates the frequency, rate, extent or location of heterochromatin formation.
regulation of heterochromatin assembly
Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.
regulation of fast-twitch skeletal muscle contraction
Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction.
regulation of slow-twitch skeletal muscle contraction
Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.
chromatin decompaction
chromatin decondensation
down regulation of heterochromatin formation
down-regulation of heterochromatin formation
downregulation of heterochromatin formation
inhibition of heterochromatin formation
negative regulation of heterochromatin assembly
Any process that activates or increases the frequency, rate or extent of heterochromatin formation.
activation of heterochromatin formation
positive regulation of heterochromatin assembly
stimulation of heterochromatin formation
up regulation of heterochromatin formation
up-regulation of heterochromatin formation
upregulation of heterochromatin formation
The chemical reactions and pathways involving glycine betaine, N-trimethylglycine.
glycine betaine metabolism
N-trimethylglycine metabolic process
N-trimethylglycine metabolism
The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine.
glycine betaine anabolism
glycine betaine biosynthesis
glycine betaine formation
glycine betaine synthesis
N-trimethylglycine biosynthesis
N-trimethylglycine biosynthetic process
Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.
CRL complex
cullin complex
cullin-RING ligase
The reformation of the nuclear membranes following their breakdown in the context of a normal process.
nuclear envelope reassembly
An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.
BAC
BMC
MCP
polyhedral organelle
A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.
PMT family mannosyltransferase complex
protein O-mannosyltransferase complex
A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
cellular protein complex localisation
cellular protein complex localization
cellular protein-containing complex localization
establishment and maintenance of cellular protein complex localization
establishment and maintenance of protein complex localization
protein complex localisation
protein complex localization
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
beta-glucan-containing cell wall organization and biogenesis
chitin- and beta-glucan-containing cell wall organisation
chitin- and beta-glucan-containing cell wall organization and biogenesis
chitin-containing cell wall organization and biogenesis
fungal-type cell wall organization and biogenesis
The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.
cell wall glycoprotein anabolism
cell wall glycoprotein biosynthesis
cell wall glycoprotein formation
cell wall glycoprotein synthesis
An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
chromatin silencing
chromatin-mediated silencing
establishment of chromatin silencing
establishment of heterochromatic silencing
establishment of heterochromatin architecture
establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region
establishment of heterochromatin architecture involved in chromatin silencing at pericentric region
heterochromatic silencing
heterochromatin assembly
heterochromatin assembly involved in chromatin silencing
heterochromatin assembly involved in chromatin silencing at centromere outer repeat region
heterochromatin assembly involved in chromatin silencing at pericentric region
heterochromatin formation involved in chromatin silencing
heterochromatin formation involved in chromatin silencing at centromere outer repeat region
heterochromatin formation involved in chromatin silencing at pericentric region
heterochromatin maintenance
TGS
transcriptional gene silencing
The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA.
centric heterochromatin formation
centromere chromatin silencing
centromeric heterochromatin biosynthesis
centromeric heterochromatin formation
centromeric silencing
chromatin silencing at centromere
chromatin silencing at centromere outer repeat region
chromatin silencing at pericentric region
heterochromatic silencing at centromere
pericentric heterochromatin assembly
A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
microtubule-based flagellum
motile cilia
motile primary cilia
motile primary cilium
motile secondary cilium
nodal cilium
A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
Polycomb Group protein complex
The portion of the plasma membrane surrounding the cell tip.
\'plasma membrane, cell tip\'
The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.
menthol metabolism
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.
ruffle organisation
ruffle organization and biogenesis
Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
regulation of anthocyanin metabolism
Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
down regulation of anthocyanin metabolic process
down-regulation of anthocyanin metabolic process
downregulation of anthocyanin metabolic process
inhibition of anthocyanin metabolic process
negative regulation of anthocyanin metabolism
Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
activation of anthocyanin metabolic process
positive regulation of anthocyanin metabolism
stimulation of anthocyanin metabolic process
up regulation of anthocyanin metabolic process
up-regulation of anthocyanin metabolic process
upregulation of anthocyanin metabolic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
regulation of anthocyanin anabolism
regulation of anthocyanin biosynthesis
regulation of anthocyanin formation
regulation of anthocyanin synthesis
Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.
proline hydroxylase activity
proline,2-oxoglutarate 4-dioxygenase activity
prolyl 4-hydroxylase activity
prolyl hydroxylase activity
Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.
HIF-type prolyl 4-hydroxylase
prolyl 4-hydroxylase
The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.
BDNF receptor signaling pathway
BDNF signalling pathway
brain-derived neurotrophic factor receptor signalling pathway
Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
regulation of BDNF receptor signaling pathway
regulation of BDNF receptor signalling pathway
regulation of brain-derived neurotrophic factor receptor signalling pathway
Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
regulation of DNA-dependent transcription, termination
regulation of DNA-templated transcription, termination
regulation of transcription termination, DNA-dependent
transcription antiterminator activity
Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.
2,3-oxidosqualene cyclase activity
The cellular process in which the contractile ring cytokinetic ring attains its fully functional state.
actomyosin contractile ring maintenance
cytokinesis, contractile ring maintenance
A signal transduction process that contributes to a cell size control checkpoint during mitosis.
mitotic cell cycle cell size control checkpoint
mitotic cell size control checkpoint
signal transduction involved in cell size control checkpoint
A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
DNA integrity checkpoint
signal transduction involved in DNA integrity checkpoint
A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.
G1 DNA damage checkpoint
G1/S DNA damage checkpoint
intracellular signal transduction involved in G1 DNA damage checkpoint
intracellular signal transduction involved in G1/S DNA damage checkpoint
intracellular signal transduction pathway involved in G1 DNA damage checkpoint
intracellular signal transduction pathway involved in G1/S DNA damage checkpoint
intracellular signaling cascade involved in G1 DNA damage checkpoint
intracellular signaling cascade involved in G1/S DNA damage checkpoint
intracellular signaling chain involved in G1 DNA damage checkpoint
intracellular signaling chain involved in G1/S DNA damage checkpoint
intracellular signaling pathway involved in G1 DNA damage checkpoint
intracellular signaling pathway involved in G1/S DNA damage checkpoint
mitotic cell cycle G1/S transition DNA damage checkpoint
mitotic G1 DNA damage checkpoint
signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
signal transduction involved in mitotic G1 DNA damage checkpoint
signal transduction via intracellular signaling cascade involved in G1 DNA damage checkpoint
signal transduction via intracellular signaling cascade involved in G1/S DNA damage checkpoint
signal transmission via intracellular cascade involved in G1 DNA damage checkpoint
A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.
signal transduction involved in spindle checkpoint
spindle checkpoint
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
lipid raft organization
membrane raft organisation
membrane raft organization and biogenesis
The process that establishes the spatial arrangement of membrane rafts within a cellular membrane.
lipid raft distribution
A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.
replication fork arrest at ribosomal DNA repeats
replication fork blocking at rDNA repeats
Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
regulation of inositol-1,4,5-triphosphate receptor activity
regulation of IP3 receptor activity
The chemical reactions and pathways involving wybutosine, 3H-imidazopurine-7-butanoic acid, 4,9-dihydro- alpha-- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.
wybutosine metabolism
yW metabolic process
yW metabolism
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
motor endplate
NMJ
Any process that modulates the rate or extent of fever generation.
regulation of pyrexia
Any process that activates or increases the frequency, rate, or extent of fever generation.
activation of fever
positive regulation of pyrexia
stimulation of fever
up regulation of fever
up-regulation of fever
upregulation of fever
The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.
T loop biosynthesis
T loop formation
t-loop biosynthesis
t-loop formation
Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
synaptic vesicle fusion
synaptic vesicle fusion to pre-synaptic membrane
synaptic vesicle fusion to presynaptic membrane
Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.
regulation of synaptic vesicle fusion to pre-synaptic membrane
regulation of synaptic vesicle fusion to presynaptic membrane
Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.
activation of synaptic vesicle fusion to presynaptic membrane
negative regulation of synaptic vesicle fusion to presynaptic membrane
positive regulation of synaptic vesicle fusion to pre-synaptic membrane
stimulation of synaptic vesicle fusion to presynaptic membrane
up regulation of synaptic vesicle fusion to presynaptic active zone membrane
up regulation of synaptic vesicle fusion to presynaptic membrane
up-regulation of synaptic vesicle fusion to presynaptic active zone membrane
up-regulation of synaptic vesicle fusion to presynaptic membrane
upregulation of synaptic vesicle fusion to presynaptic membrane
An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor, and ending with the regulation of a downstream cellular process.
inhibition of adenylate cyclase activity by opioid receptor signaling pathway
inhibition of adenylate cyclase activity by opioid receptor signalling pathway
opioid receptor, adenylate cyclase inhibiting pathway
The proteolytic processing of an inactive enzyme to an active form.
zymogen activation by proteolytic cleavage
The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
cleavage of plasminogen to plasmin
Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
killing of cells of other organism
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.
regulation of neurological process
regulation of neurological system process
regulation of neurophysiological process
Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
down regulation of neurological process
down-regulation of neurological process
downregulation of neurological process
inhibition of neurological process
negative regulation of neurological process
negative regulation of neurological system process
negative regulation of neurophysiological process
Any process that activates or increases the frequency, rate or extent of a neurophysiological process.
activation of neurological process
positive regulation of neurological process
positive regulation of neurological system process
positive regulation of neurophysiological process
stimulation of neurological process
up regulation of neurological process
up-regulation of neurological process
upregulation of neurological process
Any process that stops, prevents, or reduces the rate or extent of heat generation.
down regulation of heat generation
down-regulation of heat generation
downregulation of heat generation
inhibition of heat generation
Any process that activates or increases the rate or extent of heat generation.
activation of heat generation
stimulation of heat generation
up regulation of heat generation
up-regulation of heat generation
upregulation of heat generation
The series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
lipopolysaccharide-mediated signalling pathway
LPS-mediated signaling pathway
Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
regulation of lipopolysaccharide-mediated signalling pathway
regulation of LPS-mediated signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
down regulation of lipopolysaccharide-mediated signaling pathway
down-regulation of lipopolysaccharide-mediated signaling pathway
downregulation of lipopolysaccharide-mediated signaling pathway
inhibition of lipopolysaccharide-mediated signaling pathway
negative regulation of lipopolysaccharide-mediated signalling pathway
negative regulation of LPS-mediated signaling pathway
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
A disc
anisotropic disc
Q disc
transverse disc
A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.
I disc
isotropic disc
J disc
Binding to an adenosine receptor.
adenosine receptor ligand
Binding to an adrenergic receptor.
adrenergic receptor ligand
Binding to an angiotensin receptor.
angiotensin receptor ligand
Binding to a bombesin receptor.
bombesin receptor ligand
Binding to a bradykinin receptor.
bradykinin receptor ligand
Binding to a C5a anaphylatoxin chemotactic receptor.
C5a anaphylatoxin chemotactic receptor ligand
Binding to a cannabinoid receptor.
cannabinoid receptor ligand
Binding to a cholecystokinin receptor.
cholecystokinin receptor ligand
Binding to a cysteinyl leukotriene receptor.
cysteinyl leukotriene receptor ligand
Binding to an endothelial differentiation G protein-coupled receptor.
endothelial differentiation G-protein coupled receptor binding
endothelial differentiation G-protein coupled receptor ligand
Binding to a galanin receptor.
galanin receptor ligand
Binding to a melanin-concentrating hormone receptor.
melanin-concentrating hormone receptor ligand
Binding to a melanocortin receptor.
melanocortin receptor ligand
Binding to a melatonin receptor.
melatonin receptor ligand
Binding to a G protein-coupled (metabotropic) GABA receptor.
G-protein coupled GABA receptor binding
GABAB receptor binding
metabotropic GABA receptor binding
metabotropic GABA receptor ligand