NothingMuch/GO-Terms huggingface dataset:
Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
regulation of collagen breakdown
regulation of collagen catabolism
regulation of collagen degradation
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
regulation of collagen metabolism
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
positive regulation of collagen metabolism
Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
regulation of extracellular matrix breakdown
regulation of extracellular matrix degradation
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
positive regulation of hydrogen peroxide metabolism
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
negative regulation of hydrogen peroxide metabolism
Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
regulation of hydrogen peroxide biosynthesis
The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
protein amino acid glutathionylation
Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
regulation of protein amino acid glutathionylation
An intracellular signaling cassette that starts with the activation of protein kinase A (PKA), and ends with the regulation of a downstream cellular process, e.g. transcription. The PKA catalytic subunit (PKA-C) is normally present in a complex with its regulatory subunit, PKA-R. The inhibitory action of PKA-R is released upon cAMP binding, which results in the activation of PKA-C.
PKA signaling cascade
protein kinase A signal transduction
protein kinase A signaling cascade
protein kinase A signalling cascade
Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
regulation of PKA signaling cascade
regulation of protein kinase A signaling cascade
regulation of protein kinase A signalling cascade
Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
regulation of plasma membrane long-chain fatty acid transport
Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).
regulation of nitric oxide-mediated signal transduction
Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).
positive regulation of nitric oxide-mediated signal transduction
Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).
negative regulation of nitric oxide-mediated signal transduction
Any process that modulates the rate, frequency or extent of cGMP-mediated signaling.
regulation of cGMP-mediated signalling
Any process that increases the rate, frequency or extent of cGMP-mediated signaling.
positive regulation of cGMP-mediated signalling
Any process that decreases the rate, frequency or extent of cGMP-mediated signaling.
negative regulation of cGMP-mediated signalling
Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.
fibroblast cell migration
Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
regulation of fibroblast cell migration
Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
positive regulation of fibroblast cell migration
Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
negative regulation of fibroblast cell migration
Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
regulation of TNF signaling
regulation of TNF-mediated signaling pathway
regulation of tumor necrosis factor-mediated signalling pathway
The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
T-cell chemotaxis
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
regulation of mitochondrion organisation
Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of glucose transmembrane transport
regulation of glucose transport
Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
positive regulation of glucose transmembrane transport
positive regulation of glucose transport
Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
negative regulation of glucose transmembrane transport
negative regulation of glucose transport
Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.
regulation of protein amino acid ADP-ribosylation
The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
retinal lamination
retinal layer formation
Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
positive regulation of meiotic recombination
Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
regulation of triacylglycerol biosynthetic process
Any process in which a lipid is transported to, or maintained in, a specific location.
lipid localisation
The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
cholesterol sequestration
sequestration of cholesterol
Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.
regulation of cardiac muscle contraction by calcium ion signalling
Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
regulation of lipid sequestration
Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
positive regulation of lipid sequestration
Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
regulation of sequestering of triacylglycerol
regulation of triacylglycerol sequestration
Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
regulation of triacylglycerol catabolic process
Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
regulation of very-low-density lipoprotein particle remodelling
regulation of VLDL remodeling
regulation of VLDL remodelling
Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
regulation of UDP-glucose catabolism
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
regulation of glucose metabolism
Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
positive regulation of glucose metabolism
Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
regulation of VLDL clearance
regulation of VLDL particle clearance
Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
regulation of inositol phosphate biosynthesis
Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
negative regulation of inositol phosphate biosynthesis
Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
regulation of auxin mediated signalling pathway
Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.
positive regulation of protein maturation by peptide bond cleavage
Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
negative regulation of protein maturation by peptide bond cleavage
Any process that modulates the frequency, rate or extent of amino acid import into a cell.
regulation of amino acid import
Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation.
regulation of chromatin silencing by small RNA
regulation of heterochromatin assembly by small RNA
regulation of ncRNA-mediated heterochromatin formation
regulation of RNAi-mediated heterochromatin assembly
regulation of small non-coding RNA-mediated heterochromatin formation
The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.
establishment of localization by movement along microtubule
microtubule-based transport
movement along microtubule
Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
positive regulation of mitotic entry
Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
negative regulation of mitotic entry
Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
positive regulation of division septum formation
positive regulation of division septum formation involved in cell cycle cytokinesis
upregulation of mitotic division septum assembly
Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
inhibition of division septum assembly involved in cell cycle cytokinesis
negative regulation of division septum formation
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
regulation of neurite biosynthesis
regulation of neurite development
regulation of neurite formation
regulation of neurite growth
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
positive regulation of neurite biosynthesis
positive regulation of neurite development
positive regulation of neurite formation
positive regulation of neurite growth
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
growth cone collapse
negative regulation of neurite biosynthesis
negative regulation of neurite development
negative regulation of neurite formation
negative regulation of neurite growth
Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates.
regulation of ubiquitin homeostasis
ubiquitin homeostasis
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
response to sound
response to sound stimulus
Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
eIF2 alpha phosphorylation in response to stress
regulation of translational initiation by eIF2 alpha phosphorylation in response to stress
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
caspase-independent apoptosis
caspase-independent cell death
non-apoptotic programmed cell death
nonapoptotic programmed cell death
PCD
RCD
regulated cell death
A process which directly activates any of the steps required for programmed cell death.
induction of non-apoptotic programmed cell death
induction of nonapoptotic programmed cell death
The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
COPII coated vesicle membrane
endoplasmic reticulum to Golgi transport vesicle membrane
endoplasmic reticulum-Golgi transport vesicle membrane
ER to Golgi constitutive secretory pathway transport vesicle membrane
ER-Golgi transport vesicle membrane
The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.
TGN transport vesicle membrane
trans-Golgi network constitutive secretory pathway transport vesicle membrane
A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.
oil body
oilbody
oleosome
spherosome
The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
astrocyte cell development
The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.
oligodendrocyte cell development
The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.
microglial cell differentiation
Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
regulation of microglial cell differentiation
The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.
glia proliferation
The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.
axon regeneration in peripheral nervous system
Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.
down regulation of gliogenesis
down-regulation of gliogenesis
downregulation of gliogenesis
inhibition of gliogenesis
Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.
activation of gliogenesis
stimulation of gliogenesis
up regulation of gliogenesis
up-regulation of gliogenesis
upregulation of gliogenesis
The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.
neural rod cavitation
primary neural tube morphogenesis
primary neurulation
Any process that activates or increases the frequency, rate or extent of neuron maturation.
activation of neuron maturation
stimulation of neuron maturation
up regulation of neuron maturation
up-regulation of neuron maturation
upregulation of neuron maturation
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.
down regulation of neuron maturation
down-regulation of neuron maturation
downregulation of neuron maturation
inhibition of neuron maturation
Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.
activation of glutamate secretion
stimulation of glutamate secretion
up regulation of glutamate secretion
up-regulation of glutamate secretion
upregulation of glutamate secretion
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.
down regulation of glutamate secretion
down-regulation of glutamate secretion
downregulation of glutamate secretion
inhibition of glutamate secretion
The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.
GABA secretion
Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
regulation of GABA secretion