NothingMuch/GO-Terms huggingface dataset:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
regulation of auxin metabolism
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
positive regulation of auxin metabolism
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
negative regulation of auxin metabolism
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
regulation of tryptophan metabolism
Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
positive regulation of tryptophan metabolism
Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
regulation of mRNA editing
The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.
cotton fiber development
seed hair differentiation
seed trichome development
Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.
phagosomal acidification
The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere.
lysosome recruitment to phagosome
Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
negative regulation of EPSP
negative regulation of excitatory post-synaptic membrane potential
reduction of excitatory postsynaptic membrane potential
A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays.
SIPS
A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.
protein localization in nuclear envelope
The directed movement of lithium ions (Li+) across a membrane.
lithium ion import
lithium ion uptake
The directed movement of glutamate into the vacuole across the vacuolar membrane.
vacuolar glutamate import
The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
purine nucleotide-sugar membrane transport
purine nucleotide-sugar transport
The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
pyrimidine nucleotide-sugar membrane transport
pyrimidine nucleotide-sugar transport
Enables the transfer of a vitamin from one side of a membrane to the other.
vitamin or cofactor transporter activity
vitamin transporter activity
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA = S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide.
small RNA 2\'-O-methyltransferase
The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
secondary metabolite breakdown
secondary metabolite catabolism
secondary metabolite degradation
The directed movement of L-lysine into the vacuole across the vacuolar membrane.
lysine transmembrane import into vacuole
vacuolar lysine import
The series of molecular signals mediated by a sphingolipid.
ceramide 1-phosphate signaling pathway
ceramide signaling pathway
sphingolipid mediated signal transduction
sphingolipid signaling pathway
sphingolipid-mediated signaling pathway
sphingosine signaling pathway
The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.
vesicle tethering to plasma membrane
The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
cell septum assembly involved in cell cycle cytokinesis
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
RNA polymerase II transcription factor complex
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III.
RNA polymerase III transcription factor complex
A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
solid substrate biofilm formation
An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.
gene silencing by mRNA cleavage
mRNA cleavage involved in gene silencing by siRNA
mRNA destabilization-mediated gene silencing by siRNA
An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR).
adult seedling resistance
ARR
developmental resistance
flowering-induced resistance
mature seedling resistance
ontogenic resistance
senescence-induced resistance
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
response to OGD
A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).
telomeric circle formation
The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.
T loop disassembly
t-loop disassembly
The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
locomotor gait pattern
A G protein-coupled receptor activity that is responsible for the sense of taste.
G-protein coupled taste receptor activity
G-protein-coupled taste receptor activity
A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.
RNA localisation to nucleus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus.
cellular response to VLDL particle stimulus
The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
acetylcholine receptor signalling pathway
Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.
plasma lipoprotein particle homeostasis
Any process involved in the balance between food intake (energy input) and energy expenditure.
negative regulation of energy homeostasis
positive regulation of energy homeostasis
regulation of energy homeostasis
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.
eIF-4F assembly
eIF4F assembly
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
response to GM-CSF
response to granulocyte macrophage colony-stimulating factor stimulus
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
cilial cytoplasm
ciliary cytoplasm
cilium cytoplasm
cilium plasm
microtubule-based flagellar cytoplasm
microtubule-based flagellar matrix
microtubule-based flagellum cytoplasm
microtubule-based flagellum matrix
The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.
lymphocyte homing
Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.
dendritic extension
The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes.
perinuclear ER
A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.
M1 linkage
Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
dendritic cell apoptosis
Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
motoneuron apoptosis
motor neuron apoptosis
Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.
pancreatic B cell apoptosis
pancreatic beta cell apoptosis
type B pancreatic cell apoptosis
The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
L-kynurenine metabolism
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
dendritic spine organisation
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
response to thyroid hormone stimulus
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.
response to T4
response to T4 stimulus
response to thyroxine stimulus
A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.
IRF complex
The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
vascular smooth muscle cell fate commitment
The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
vascular smooth muscle cell development
The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IL-17A production
interleukin-17A biosynthetic process
The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.
methyl-branched fatty acid metabolism
A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
pre-synaptic membrane organization
presynaptic membrane organisation
The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.
polyacyltrehalose metabolism
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
post-synaptic membrane assembly
The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
pre-synaptic membrane assembly
A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.
post synaptic density organization
post-synaptic density organization
postsynaptic density organisation
PSD organization
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.
post synaptic density assembly
post-synaptic density assembly
PSD assembly
The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering
AMPA receptor clustering
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
Dlg4 clustering
post-synaptic density protein 95 clustering
PSD-95 clustering
Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
receptor localisation to synapse
Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
mesenchymal cell apoptosis
Binding to an intronic sequence of a pre-messenger RNA (pre-mRNA).
pre-messenger RNA intronic binding
pre-mRNA intron binding
The chemical reactions and pathways involving the ammonium ion.
ammonium ion metabolism
ammonium metabolic process
The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
MSC proliferation
The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.
ADP-L-glycero-beta-D-manno-heptose metabolism
The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.
N-acetylmuramate metabolic process
N-acetylmuramate metabolism
N-acetylmuramic acid metabolism
The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.
N-acetylmuramate breakdown
N-acetylmuramate catabolic process
N-acetylmuramate catabolism
N-acetylmuramate degradation
N-acetylmuramic acid breakdown
N-acetylmuramic acid catabolism
N-acetylmuramic acid degradation
The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.
1,6-anhydro-N-acetyl-beta-muramate metabolic process
1,6-anhydro-N-acetyl-beta-muramate metabolism
1,6-anhydro-N-acetyl-beta-muramic acid metabolism
1,6-anhydro-N-acetylmuramic acid metabolic process
1,6-anhydro-N-acetylmuramic acid metabolism
The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers.
epoxide metabolism
The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42.
membrane ruffle formation
membrane ruffling
A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity.
peptidase inhibitor complex
A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity.
serine-type endopeptidase inhibitor complex
serpin complex
The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.
enamel development
The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.
dentin development
dentine development
The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
apoptotic signalling pathway
induction of apoptosis by extracellular signals
The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
death receptor-mediated apoptosis
extrinsic apoptosis
extrinsic apoptotic pathway
extrinsic apoptotic signaling pathway in presence of ligand
extrinsic apoptotic signalling pathway
The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
dependence receptor signaling pathway
extrinsic apoptosis in absence of ligand
extrinsic apoptotic signalling pathway in absence of ligand
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).
induction of apoptosis by intracellular signals
intrinsic apoptosis
intrinsic apoptotic pathway
intrinsic apoptotic signalling pathway
mitochondrial-mediated apoptotic pathway
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
apoptosis
execution phase of apoptotic process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
response to GnRH
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
lysosomal membrane organisation
lysosome membrane organization
Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
regulation of lysosome membrane permeability
The process in which chromatin is anchored to the nuclear envelope.
attachment of chromatin to nuclear envelope
The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.
beta-amyloid clearance
Binding to a flavanol.
flavan-3-ol binding