NothingMuch/GO-Terms huggingface dataset:
The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
acetyl-CoA breakdown
acetyl-CoA catabolism
acetyl-CoA degradation
The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid.
butanoic acid anabolism
butanoic acid biosynthesis
butanoic acid biosynthetic process
butanoic acid formation
butanoic acid synthesis
butyrate anabolism
butyrate biosynthesis
butyrate formation
butyrate synthesis
The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.
2-oxobutyrate metabolism
alpha-ketobutyrate metabolic process
alpha-ketobutyrate metabolism
The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.
ribitol breakdown
ribitol catabolism
ribitol degradation
The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
monosaccharide anabolism
monosaccharide biosynthesis
monosaccharide formation
monosaccharide synthesis
The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
monosaccharide breakdown
monosaccharide catabolism
monosaccharide degradation
The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.
GDP-L-fucose metabolism
The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose.
galactose anabolism
galactose biosynthesis
galactose formation
galactose synthesis
The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.
dTDP-mannose metabolism
The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides.
D-arabinose metabolism
The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc.
L-arabinose metabolism
The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
teichoic acid metabolism
The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.
K antigen metabolism
The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.
GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolism
The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues.
colanic acid metabolism
The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.
enterobacterial common antigen metabolism
The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.
CMP-N-acetylneuraminate metabolism
The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.
GDP-D-rhamnose metabolism
The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.
dTDP-rhamnose metabolism
The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.
2-deoxyribose 1-phosphate metabolism
deoxyribose 1-phosphate metabolic process
deoxyribose 1-phosphate metabolism
The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
deoxyribose phosphate anabolism
deoxyribose phosphate biosynthesis
deoxyribose phosphate formation
deoxyribose phosphate synthesis
The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
deoxyribose phosphate breakdown
deoxyribose phosphate catabolism
deoxyribose phosphate degradation
The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.
deoxyribose 1,5-bisphosphate metabolism
The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose.
deoxyribose 5-phosphate metabolism
The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.
ribose phosphate anabolism
ribose phosphate biosynthesis
ribose phosphate formation
ribose phosphate synthesis
The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
5-phosphoribose 1-diphosphate metabolism
PRPP metabolic process
The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
carboxylic acid anabolism
carboxylic acid biosynthesis
carboxylic acid formation
carboxylic acid synthesis
The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
carboxylic acid breakdown
carboxylic acid catabolism
carboxylic acid degradation
The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls.
D-galacturonate metabolism
The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid.
galacturonate breakdown
galacturonate catabolism
galacturonate degradation
The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
UDP-glucuronate metabolism
The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid.
glucuronate anabolism
glucuronate biosynthesis
glucuronate formation
glucuronate synthesis
The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.
KDO metabolic process
KDO metabolism
keto-3-deoxy-D-manno-octulosonic acid metabolism
ketodeoxyoctanoate metabolic process
The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains.
lipopolysaccharide core region metabolism
LPS core region metabolic process
The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.
O antigen metabolism
The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.
phenylmercury acetate metabolism
The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom.
organomercury anabolism
organomercury biosynthesis
organomercury formation
organomercury synthesis
The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
urate metabolism
The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids.
D-amino acid metabolism
The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid.
chorismate metabolism
Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT.
regulation of STAT protein import into nucleus
regulation of STAT protein nuclear translocation
STAT protein import into nucleus
Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.
down regulation of JAK-STAT cascade
down-regulation of JAK-STAT cascade
downregulation of JAK-STAT cascade
inhibition of JAK-STAT cascade
negative regulation of STAT protein import into nucleus
negative regulation of STAT protein nuclear translocation
Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
activation of JAK-STAT cascade
positive regulation of STAT protein import into nucleus
positive regulation of STAT protein nuclear translocation
stimulation of JAK-STAT cascade
up regulation of JAK-STAT cascade
up-regulation of JAK-STAT cascade
upregulation of JAK-STAT cascade
The chemical reactions and pathways involving non-phosphorylated forms of glucose.
non-phosphorylated glucose metabolism
The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate).
(R)-4-hydroxymandelate metabolism
The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
2\'-(5\'\'-triphosphoribosyl)-3\'-dephospho-CoA metabolism
The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms.
2-aminoethylphosphonate metabolism
2-phosphonoethylamine metabolic process
2-phosphonoethylamine metabolism
ciliatine metabolic process
ciliatine metabolism
The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.
organophosphate breakdown
organophosphate catabolism
organophosphate degradation
The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.
3-(3-hydroxy)phenylpropionate metabolism
The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid.
D-alanine metabolism
The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids.
D-amino acid anabolism
D-amino acid biosynthesis
D-amino acid formation
D-amino acid synthesis
The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.
D-cysteine metabolism
The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.
L-cysteine metabolism
The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid.
L-lysine metabolism
The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.
D-lysine metabolism
The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.
aerobactin metabolism
The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide.
FAD metabolism
oxidized flavin adenine dinucleotide metabolic process
oxidized flavin adenine dinucleotide metabolism
oxidized flavin-adenine dinucleotide metabolic process
oxidized flavin-adenine dinucleotide metabolism
The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
FMN metabolism
The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.
benzyl isoquinoline alkaloid metabolism
The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.
purine alkaloid metabolism
The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).
terpenoid indole alkaloid metabolism
The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.
tropane alkaloid metabolism
The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.
creatinine metabolism
The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms.
desthiobiotin metabolic process
desthiobiotin metabolism
dethiobiotin metabolism
The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
diaminopimelate metabolism
The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate.
dihydrofolate metabolism
dihydrofolate reduction
The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.
dipyrrin metabolism
The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.
dimethylsilanediol metabolism
The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon.
organosilicon breakdown
organosilicon catabolism
organosilicon degradation
organosilicone catabolic process
organosilicone catabolism
The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.
eicosanoid biosynthesis
eicosanoid biosynthetic process
eoxin biosynthesis
eoxin synthesis
icosanoid anabolism
icosanoid biosynthesis
icosanoid formation
icosanoid synthesis
The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure.
prostanoid anabolism
prostanoid biosynthesis
prostanoid formation
prostanoid synthesis
The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.
hexadecanal metabolism
The chemical reactions and pathways involving a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.
short-chain fatty acid metabolism
The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.
neutral lipid anabolism
neutral lipid biosynthesis
neutral lipid formation
neutral lipid synthesis
The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity.
neutral lipid breakdown
neutral lipid catabolism
neutral lipid degradation
The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
monoacylglycerol metabolism
monoglyceride metabolic process
monoglyceride metabolism
The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
acylglycerol anabolism
acylglycerol biosynthesis
acylglycerol formation
acylglycerol synthesis
The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
acylglycerol breakdown
acylglycerol catabolism
acylglycerol degradation
The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes.
dolichyl diphosphate metabolism
The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.
membrane lipid breakdown
membrane lipid catabolism
membrane lipid degradation
membrane lipid peroxidation
The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.
membrane lipid anabolism
membrane lipid biosynthesis
membrane lipid formation
membrane lipid synthesis
The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria.
phosphatidyl-N-monomethylethanolamine metabolism
PMME metabolic process
PMME metabolism
The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
PAF metabolic process
PAF metabolism
platelet activating factor metabolism
The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
phosphatidylcholine metabolism
The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.
phosphatidylglycerol metabolism
The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
phosphatidic acid metabolism
The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
glycerophospholipid anabolism
glycerophospholipid biosynthesis
glycerophospholipid formation
glycerophospholipid synthesis
phosphoglyceride biosynthesis
phosphoglyceride biosynthetic process
The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
glycerophospholipid breakdown
glycerophospholipid catabolism
glycerophospholipid degradation
phosphoglyceride catabolic process
phosphoglyceride catabolism
The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
glycosylceramide anabolism
glycosylceramide biosynthesis
glycosylceramide formation
glycosylceramide synthesis
The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
glycosylceramide breakdown
glycosylceramide catabolism
glycosylceramide degradation
The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
lactosylceramide metabolism
The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
glycosphingolipid breakdown
glycosphingolipid catabolism
glycosphingolipid degradation
The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.
4-aminobenzoic acid metabolic process
4-aminobenzoic acid metabolism
p-aminobenzoic acid metabolic process
p-aminobenzoic acid metabolism
PABA metabolic process
PABA metabolism
para-aminobenzoic acid metabolism
vitamin Bx metabolic process
vitamin Bx metabolism
The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.
oxazole or thiazole metabolism
The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.
ether lipid metabolism
plasmalogen metabolic process
The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.
glycerolipid metabolism
The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.
glyoxylate metabolism
The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
phosphatidylinositol metabolism
phosphoinositide metabolic process
phosphoinositide metabolism
PtdIns metabolic process
PtdIns metabolism
The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
IPP metabolic process
IPP metabolism
isopentenyl diphosphate metabolism
isopentenyl pyrophosphate metabolic process
isopentenyl pyrophosphate metabolism
The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.
L-methylmalonyl-CoA metabolism
The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.
haem B metabolic process
haem B metabolism
heme B metabolism
protoheme metabolic process
protoheme metabolism