NothingMuch/GO-Terms huggingface dataset:
The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.
inner renal medulla development
Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.
positive regulation of metanephros formation
The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.
specification of ureteric bud anterior/posterior asymmetry
The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
head kidney structural organisation
The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.
ureteric bud mesenchymal cell proliferation
The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure.
S1 cell development
The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney.
S1 cell fate commitment
The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.
Wolffian duct formation
Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
negative regulation of ureter mesenchymal cell proliferation
negative regulation of ureteral mesenchymal cell proliferation
Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.
cell-cell signalling involved in metanephros development
The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.
metanephric kidney pyramid development
metanephric pyramid development
metanephric renal medulla development
metanephric renal pyramid development
The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.
metanephric S3 development
The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.
metanephric S1 development
The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride.
metanephric S2 development
The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.
metanephric TAL development
The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure.
metanephric distal convoluted tubule cell development
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.
metanephric distal convoluted tubule cell fate commitment
The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
metanephric Bowman\'s capsule development
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
metanephric Bowman\'s capsule cell fate commitment
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.
metanephric glomerular visceral epithelial cell fate commitment
The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure.
metanephros interstitial cell development
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast.
metanephros interstitial cell fate commitment
The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
metanephric Goormaghtigh proliferation
metanephric lacis cell proliferation
Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros.
establishment of planar cell polarity involved in metanephric nephron morphogenesis
The process in which the loop of Henle of the metanephric nephron acquires its identity.
specification of metanephric intermediate tubule identity
Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis
negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis
Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis
positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis
Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
swell-activated chloride channel
The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall.
chaperone-mediated protein transport across periplasmic space
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.
response to anaesthetic
Catalysis of the reaction: histone H3-threonine (position 3) + ATP = histone H3-phosphothreonine (position 3) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 3 of histone H3.
histone H3-T3 kinase activity
histone kinase activity (H3-T3 specific)
histone threonine kinase activity (H3-T3 specific)
histone-threonine kinase activity (H3-T3 specific)
Catalysis of the reaction: histone H2A-serine (position 121) + ATP = histone H2A-phosphoserine (position 121) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 121 of histone H2A.
histone H2A-S121 kinase activity
histone kinase activity (H2A-S121 specific)
histone serine kinase activity (H2A-S121 specific)
histone-serine kinase activity (H2A-S121 specific)
The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
middle-term memory
MTM
A protein complex found in yeast that contains GET4, MDY2 (GET5), SGT2, and at least two heat shock proteins, HSP104 and YBR137W. The TRC complex transfers tail-anchored (TA) proteins to GET3 for targeting to the endoplasmic reticulum membrane.
GET4-GET5 transmembrane domain recognition complex
TMD recognition complex
The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
microtubule minus-end-directed vesicle distribution
microtubule minus-end-directed vesicle localization
The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
FAD or FADH2 catabolic process
flavin adenine dinucleotide breakdown
flavin adenine dinucleotide catabolism
flavin adenine dinucleotide degradation
A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling.
intra-S DNA damage checkpoint effector process
response to signal involved in intra-S DNA damage checkpoint
A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling.
mitotic G2/M transition decatenation checkpoint effector process
mitotic G2/M transition DNA damage checkpoint effector process
response to mitotic G2/M transition decatenation checkpoint signaling
response to mitotic G2/M transition DNA damage checkpoint signaling
response to signal involved in mitotic G2/M transition decatenation checkpoint
response to signal involved in mitotic G2/M transition DNA damage checkpoint
A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling.
meiotic DNA replication checkpoint effector process
response to signal involved in meiotic DNA replication checkpoint
A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling.
mitotic DNA replication checkpoint effector process
response to S-M checkpoint signaling
response to signal involved in mitotic DNA replication checkpoint
response to signal involved in S-M checkpoint
S-M checkpoint effector process
A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling.
mitotic cell cycle G1/S transition size control checkpoint effector process
response to signal involved in mitotic cell cycle G1/S transition size control checkpoint
A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling.
G2/M transition size control checkpoint effector process
response to G2/M transition size control checkpoint signaling
response to mitotic cell cycle G2/M transition size control checkpoint signaling
response to signal involved in G2/M transition size control checkpoint
A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling.
meiotic recombination checkpoint effector process
response to signal involved in meiotic recombination checkpoint
A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling.
meiotic spindle assembly checkpoint effector process
response to signal involved in meiotic spindle assembly checkpoint
A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling.
mitotic cell cycle spindle orientation checkpoint effector process
response to signal involved in mitotic cell cycle spindle orientation checkpoint
The process in which methylammonium is transported across a membrane.
methylammonium membrane transport
The volume enclosed by the membranes of the host cell endosome.
host endosome lumen
A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.
host cell multivesicular body
A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction.
coiled body of host
host cell coiled body
Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).
negative regulation of second heart field cardioblast proliferation
A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place.
host cell viral assembly site
host cell virion assembly compartment
viral assembly compartment
viral assembly site
virion assembly compartment
Rho GTPase-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
Rho-associated protein kinase activity
ROCK kinase activity
A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain.
PNN
A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.
IL-23 receptor complex
Catalysis of the reaction: -dithiol + ONOO- = -disulfide + NO2- + H2O.
peroxynitritase activity
Binding to L-tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
L-Tyr binding
tyrosine binding
A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6.
endoplasmic reticulum membrane protein complex
ER membrane protein complex
Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O.
tricoumaroyl spermidine meta-hydroxylase activity
Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O.
triferuloyl spermidine meta-hydroxylase activity
Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.
7beta-ketosteroid reductase activity
An inflammasome complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential.
NALP1 inflammasome complex
An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus.
NALP3 inflammasome complex
A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
pancreatic B cell maturation
pancreatic beta cell maturation
Binding to monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
mADPr binding
mono-ADP-ribose binding
Binding to polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.
pADPr binding
poly-ADP-ribose binding
Tolerance induction directed at lipopolysaccharide antigens.
tolerance induction to endotoxin
tolerance induction to LPS
The modification of a lysine residue in a protein to produce (2S)-2-amino-6-(amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).
EF-P modification pathway
Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.
xanthosine ribohydrolase activity
A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs.
nucleoplasmic box H/ACA RNP pseudouridylase complex
The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IL-28A production
IL28A production
interferon lambda 2 production
interleukin-28A secretion
The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IL-28B production
IL28B production
interferon lambda 3 production
interleukin-28B secretion
The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IL-29 production
IL29 production
interferon lambda 1 production
interleukin-29 secretion
The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IL-30 production
interleukin-30 complex production
interleukin-30 secretion
The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IL-31 production
interleukin-31 secretion
The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IFN-delta production
IFND production
interferon-delta secretion
The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IFN-epsilon production
IFNE production
interferon-epsilon secretion
The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IFN-kappa production
IFNK production
interferon-kappa secretion
The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IFN-tau production
IFN-tau secretion
IFNT production
interferon-tau secretion
The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IFN-omega production
IFNW production
interferon-omega secretion
A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.
tRNA splicing ligase complex
The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base).
mitochondrial tRNA t6A modification
The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.
MAD
mitochondria-associated protein catabolic process
mitochondria-associated protein degradation
mitochondrion-associated protein catabolic process
The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling.
MRN complex assembly
MRX complex assembly
Rad50 complex assembly
RAD50-MRE11-NBN complex assembly
Rad50-Rad32-Nbs1 complex assembly
RMX complex assembly
Any process in which a SHREC complex is transported to, or maintained in, a specific location.
establishment and maintenance of SHREC complex localization
SHREC complex localisation
A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods.
stationary phase
vegetative growth of a single-celled organism
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.
cellular response to bismuth ion
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.
cellular response to MMS
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.
cellular response to 2-sulfanylethanol
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.
cellular response to SDS
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
cellular response to glucitol
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
cellular response to HU