NothingMuch/GO-Terms huggingface dataset:
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
proximal-distal pattern formation involved in metanephric nephron development
proximal/distal metanephric nephron patterning
The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.
metanephric connecting duct development
Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis
regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis
The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.
clathrin-coat disassembly
clathrin-coat uncoating
clathrin-coated vesicle uncoating
A protein depolymerization process that results in the disassembly of vesicle coat proteins.
vesicle coat disassembly
The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.
monocarboxylic acid anabolism
monocarboxylic acid biosynthesis
monocarboxylic acid formation
monocarboxylic acid synthesis
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator
signal transduction by p53 class mediator resulting in induction of apoptosis
The process in which UDP-galactose is transported across a membrane.
UDP-galactose membrane transport
UDP-galactose transport
The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
amino acid derivative transport
The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
cellular lactam metabolic process
cellular lactam metabolism
The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
cellular lactam anabolism
cellular lactam biosynthesis
cellular lactam biosynthetic process
cellular lactam formation
cellular lactam synthesis
The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
cellular lactam breakdown
cellular lactam catabolic process
cellular lactam catabolism
cellular lactam degradation
Binding to a modified amino acid.
amino acid derivative binding
The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
sulfur-containing compound transport
Enables the transfer of modified amino acids from one side of a membrane to the other.
amino acid derivative transmembrane transporter activity
modified amino acid transporter activity
The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).
tricarboxylic acid metabolism
The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.
tricarboxylate biosynthesis
tricarboxylate biosynthetic process
tricarboxylic acid anabolism
tricarboxylic acid biosynthesis
tricarboxylic acid formation
tricarboxylic acid synthesis
The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.
tricarboxylate catabolic process
tricarboxylate catabolism
tricarboxylic acid breakdown
tricarboxylic acid catabolism
tricarboxylic acid degradation
A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.
chromosomal passenger complex localization to kinetochore
chromosome passenger complex localisation to kinetochore
CPC complex localization to kinetochore
CPC localization to kinetochore
The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.
cardiovascular system development
A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.
protein activation pathway
protein activitory cascade
A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.
endoplasmic reticulum membrane insertion complex
The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
microtubule plus-end-directed vesicle distribution
microtubule plus-end-directed vesicle localization
The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
microtubule-based organelle localization
The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
microtubule minus-end-directed organelle distribution
microtubule minus-end-directed organelle localization
The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
microtubule plus-end-directed organelle distribution
microtubule plus-end-directed organelle localization
The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
FAD or FADH2 metabolic process
flavin adenine dinucleotide metabolism
flavin-adenine dinucleotide metabolic process
The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
FAD or FADH2 biosynthetic process
flavin adenine dinucleotide anabolism
flavin adenine dinucleotide biosynthesis
flavin adenine dinucleotide formation
flavin adenine dinucleotide synthesis
Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center.
microtubule anchoring at microtubule organising centre
microtubule anchoring at MTOC
A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.
cell cycle checkpoint effector process
G1/S transition checkpoint effector process
G2/M transition checkpoint effector process
response to G1/S transition checkpoint signaling
response to G2/M transition checkpoint signaling
response to signal involved in cell cycle checkpoint
response to signal involved in G1/S transition checkpoint
response to signal involved in G2/M transition checkpoint
A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling.
cytokinesis checkpoint effector process
response to signal involved in cytokinesis checkpoint
A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling.
DNA integrity checkpoint effector process
response to signal involved in DNA integrity checkpoint
A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint.
meiotic cell cycle checkpoint effector process
response to signal involved in meiotic cell cycle checkpoint
A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling.
mitotic cell cycle checkpoint effector process
mitotic cell cycle G1/S checkpoint effector process
mitotic G2/M transition checkpoint effector process
response to mitotic cell cycle G1/S checkpoint signaling
response to mitotic G2/M transition checkpoint signal
response to signal involved in mitotic cell cycle checkpoint
response to signal involved in mitotic cell cycle G1/S checkpoint
response to signal involved in mitotic G2/M transition checkpoint
A process that occurs in response to signals generated as a result of spindle checkpoint signaling.
response to signal involved in spindle checkpoint
spindle checkpoint effector process
A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling.
DNA damage checkpoint effector process
response to signal involved in DNA damage checkpoint
A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling.
G2/M transition DNA damage checkpoint effector process
response to signal involved in G2/M transition DNA damage checkpoint
A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling.
mitotic cell cycle G1/S transition DNA damage checkpoint effector process
response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling
response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint
A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling.
DNA replication checkpoint effector process
response to signal involved in DNA replication checkpoint
A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.
cell size control checkpoint effector process
response to mitotic cell cycle cell size control checkpoint signaling
response to signal involved in cell size control checkpoint
A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling.
mitotic cell cycle spindle checkpoint effector process
response to mitotic cell cycle spindle checkpoint signaling
response to signal involved in mitotic cell cycle spindle checkpoint
A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.
mitotic cell cycle spindle assembly checkpoint effector process
response to Dma1-dependent checkpoint signaling
response to Dma1-dependent checkpoint signalling
response to signal involved in mitotic cell cycle spindle assembly checkpoint
A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling.
response to signal involved in spindle assembly checkpoint
spindle assembly checkpoint effector process
The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.
ammonia transport
ammonium membrane transport
ammonium transport
The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives.
toluene and derivative metabolic process
toluene-containing compound metabolism
The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.
toluene and derivative catabolic process
toluene-containing compound breakdown
toluene-containing compound catabolism
toluene-containing compound degradation
Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.
Pup conjugating enzyme activity
The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.
photoreceptor cell axon pathfinding
The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
purine and derivative metabolic process
purine-containing compound metabolism
The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
purine and derivative biosynthetic process
purine-containing compound anabolism
purine-containing compound biosynthesis
purine-containing compound formation
purine-containing compound synthesis
The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
purine and derivative catabolic process
purine-containing compound breakdown
purine-containing compound catabolism
purine-containing compound degradation
The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
pyridine and derivative metabolic process
pyridine-containing compound metabolism
The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
pyridine and derivative biosynthetic process
pyridine-containing compound anabolism
pyridine-containing compound biosynthesis
pyridine-containing compound formation
pyridine-containing compound synthesis
The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
pyridine and derivative catabolic process
pyridine-containing compound breakdown
pyridine-containing compound catabolism
pyridine-containing compound degradation
The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
pyrimidine and derivative metabolic process
pyrimidine-containing compound metabolism
The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
pyrimidine and derivative biosynthetic process
pyrimidine-containing compound anabolism
pyrimidine-containing compound biosynthesis
pyrimidine-containing compound formation
pyrimidine-containing compound synthesis
The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
pyrimidine and derivative catabolic process
pyrimidine-containing compound breakdown
pyrimidine-containing compound catabolism
pyrimidine-containing compound degradation
The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.
purine-containing compound membrane transport
The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof.
pyrimidine-containing compound membrane transport
The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
RANKL production
TNFSF11 production
tumor necrosis factor ligand superfamily member 11 production
An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.
Th17 immune response
The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
T-helper 17 cell development
The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
T-helper 17 cell fate commitment
Th17 cell lineage commitment
Th17 fate commitment
Binds to and increases the activity of a protein phosphatase.
protein phosphatase 2 activator activity
protein phosphatase type 1 activator activity
protein phosphatase type 2A activator activity
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
bouton organization
presynaptic bouton organization
synaptic bouton organization
terminal bouton organization
terminal button organisation
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
cell membrane microparticle
The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell.
microparticle generation
microparticle release
The cellular component organization process in which microparticles bud off from an endothelial cell.
endothelial microparticle generation
endothelial microparticle release
The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CXCL1 production
KC production
keratinocyte derived chemokine production
SCYB1 production
The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CXCL2 production
MIP-2 production
MIP2 production
SCYB2 production
Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
ADP-ribose binding
Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
apoptosis of endothelial cells
endothelial cell apoptosis
endothelial cell programmed cell death by apoptosis
killing of endothelial cells
programmed cell death of endothelial cells by apoptosis
programmed cell death, endothelial cells
An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
clathrin coated pit-dependent endocytosis
clathrin-mediated endocytosis
CME
An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers.
caveolae-dependent endocytosis
caveolae-mediated endocytosis
caveolin-dependent endocytosis
A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex.
box H/ACA snoRNP pseudouridylase complex
sRNP complex
The chemical reactions and pathways involving diatomic oxygen (O2).
diatomic oxygen metabolic process
oxygen metabolism
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
reactive oxygen species metabolism
ROS metabolic process
The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
establishment of protein localisation to organelle
Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
maintenance of protein localisation to organelle
maintenance of protein localization to organelle
The directed movement of a protein to a specific location in a chloroplast.
establishment of protein localisation to chloroplast
A process in which a protein is transported to, or maintained at, a location in a chloroplast.
protein localisation to chloroplast
The directed movement of a protein to a specific location in the endoplasmic reticulum.
establishment of protein localisation to endoplasmic reticulum
establishment of protein localisation to ER
establishment of protein localization in endoplasmic reticulum
establishment of protein localization to ER
The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
IL-32 production
IL32 production
interleukin-32 biosynthetic process
interleukin-32 secretion
NK4 production
TAIF production