NothingMuch/GO-Terms huggingface dataset:
Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
activation of telomere maintenance via semi-conservative replication
stimulation of telomere maintenance via semi-conservative replication
up regulation of telomere maintenance via semi-conservative replication
up-regulation of telomere maintenance via semi-conservative replication
upregulation of telomere maintenance via semi-conservative replication
Catalysis of the reaction: glucosaminyl-phosphatidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phasphotidylinositol + CoA.
glucosaminyl-phosphotidylinositol O-acyltransferase activity
GPI-inositol acyltransferase
Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.
riboflavin transporter activity
The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy.
cell wall macromolecule catabolic process during cytogamy
The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy.
plasma membrane fusion during cytogamy
plasma membrane organization involved in conjugation with cellular fusion
A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).
Clr6 histone deacetylase complex II
Clr6 histone deacetylase complex II\'
Clr6-CII complex
Clr6S complex
Rpd3C(S)
Rpd3S
Sin3S
Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
activation of synaptic transmission, dopaminergic
stimulation of synaptic transmission, dopaminergic
up regulation of synaptic transmission, dopaminergic
up-regulation of synaptic transmission, dopaminergic
upregulation of synaptic transmission, dopaminergic
Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
down regulation of synaptic transmission, dopaminergic
down-regulation of synaptic transmission, dopaminergic
downregulation of synaptic transmission, dopaminergic
inhibition of synaptic transmission, dopaminergic
Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
down regulation of synaptic transmission, GABAergic
down-regulation of synaptic transmission, GABAergic
downregulation of synaptic transmission, GABAergic
inhibition of synaptic transmission, GABAergic
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
activation of synaptic transmission, GABAergic
stimulation of synaptic transmission, GABAergic
up regulation of synaptic transmission, GABAergic
up-regulation of synaptic transmission, GABAergic
upregulation of synaptic transmission, GABAergic
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
down regulation of adenosine transport
down-regulation of adenosine transport
downregulation of adenosine transport
inhibition of adenosine transport
Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
activation of adenosine transport
stimulation of adenosine transport
up regulation of adenosine transport
up-regulation of adenosine transport
upregulation of adenosine transport
The directed movement of a dense core granule to a specific location.
establishment of dense core granule localisation
establishment of dense core vesicle localization
Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.
maintenance of dense core granule localization
maintenance of dense core vesicle location
Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.
phosphatidylinositol 3-phosphate binding
PtdIns-3-P binding
Catalysis of the reaction: ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H+ + lysidine(34) in tRNA(Ile2). This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine.
tRNA(Ile)-2-lysyl-cytidine synthase activity
tRNA(Ile)-lysidine synthetase activity
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
AMPA receptor
AMPA-selective glutamate receptor complex
The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.
central nervous system myelin sheath maintenance
myelin maintenance in central nervous system
The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.
myelin maintenance in peripheral nervous system
peripheral nervous system myelin sheath maintenance
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.
central nervous system myelin sheath formation
myelin formation in central nervous system
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.
myelin formation in peripheral nervous system
peripheral nervous system myelin sheath formation
The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system.
ensheathment of non-myelinated axons in central nervous system
The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons.
ensheathment of non-myelinated axons in peripheral nervous system
A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.
RNase H2 complex
A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.
MMR complex
MSH2/MSH6 complex
A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.
MMR complex
MSH2/MSH3 complex
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
down regulation of prostaglandin secretion
down-regulation of prostaglandin secretion
downregulation of prostaglandin secretion
inhibition of prostaglandin secretion
negative regulation of prostacyclin secretion
A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.
angiogenin-placental ribonuclease inhibitor complex
The chemical reactions and pathways resulting in the breakdown of lipoate.
lipoic acid breakdown
lipoic acid catabolism
lipoic acid degradation
The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
Mo-molybdopterin cofactor breakdown
Mo-molybdopterin cofactor catabolism
Mo-molybdopterin cofactor degradation
Moco catabolic process
Moco catabolism
The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
Moco catabolic process
Moco catabolism
W-molybdopterin cofactor breakdown
W-molybdopterin cofactor catabolism
W-molybdopterin cofactor degradation
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.
down regulation of activin secretion
down-regulation of activin secretion
downregulation of activin secretion
inhibition of activin secretion
Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.
activation of activin secretion
stimulation of activin secretion
up regulation of activin secretion
up-regulation of activin secretion
upregulation of activin secretion
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.
down regulation of inhibin secretion
down-regulation of inhibin secretion
downregulation of inhibin secretion
inhibition of inhibin secretion
Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell.
activation of inhibin secretion
stimulation of inhibin secretion
up regulation of inhibin secretion
up-regulation of inhibin secretion
upregulation of inhibin secretion
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
down regulation of aldosterone biosynthetic process
down-regulation of aldosterone biosynthetic process
downregulation of aldosterone biosynthetic process
inhibition of aldosterone biosynthetic process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
activation of aldosterone biosynthetic process
stimulation of aldosterone biosynthetic process
up regulation of aldosterone biosynthetic process
up-regulation of aldosterone biosynthetic process
upregulation of aldosterone biosynthetic process
Binding to a DNA region containing an oxidized pyrimidine residue.
oxidised pyrimidine DNA binding
oxidized pyrimidine base DNA binding
oxidized pyrimidine nucleobase DNA binding
The molecular events that lead to the excision of a viral genome from the host genome.
prophage excision
A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell.
cellular oxygen homeostasis
oxygen homeostasis
A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
MLH1/PMS2 complex
MMR complex
MutL-alpha complex
A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.
MLH1/PMS1 complex
MMR complex
Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
alpha-beta T cell receptor activity
gamma-delta T cell receptor activity
T cell receptor activity
Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
down regulation of sodium:hydrogen antiporter activity
down-regulation of sodium:hydrogen antiporter activity
downregulation of sodium:hydrogen antiporter activity
inhibition of sodium:hydrogen antiporter activity
negative regulation of sodium:hydrogen antiporter activity
Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
activation of sodium:hydrogen antiporter activity
positive regulation of sodium:hydrogen antiporter activity
stimulation of sodium:hydrogen antiporter activity
up regulation of sodium:hydrogen antiporter activity
up-regulation of sodium:hydrogen antiporter activity
upregulation of sodium:hydrogen antiporter activity
Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
PNR element binding
Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.
down regulation of mismatch repair
down-regulation of mismatch repair
downregulation of mismatch repair
inhibition of mismatch repair
Any process that activates or increases the frequency, rate or extent of mismatch repair.
activation of mismatch repair
stimulation of mismatch repair
up regulation of mismatch repair
up-regulation of mismatch repair
upregulation of mismatch repair
Binding to a GTPase protein binding domain (GDB) domain. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac.
Cdc42/Rac interactive binding motif binding
CRIB motif binding
P21-Rho-binding domain binding
PMD binding
Any process that initiates the activity of the inactive enzyme phospholipase A2.
phospholipase A2 activation
Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.
PCBER activity
A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.
ARF complex
A protein complex comprising Bcl10, MALT1 and a CARD domain-containing protein (CARD9, CARD10 or CARD11); plays a role in signal transduction during NF-kappaB activation.
CARMA1-BCL10-Malt1 complex
The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.
beta-nerve growth factor processing
NGF processing
The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.
direct endocytic recycling
Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.
calcium ion homeostasis in Golgi
Golgi calcium ion concentration regulation
regulation of calcium ion concentration in Golgi
regulation of Golgi calcium ion concentration
The external (cytoplasmic) face of the mitochondrial outer membrane.
cytosolic side of mitochondrial outer membrane
external leaflet of mitochondrial outer membrane
external side of mitochondrial envelope
external side of mitochondrial outer membrane
A homodimeric complex that possesses polyprenyl diphosphate synthase activity involved in the synthesis of the isoprenoid chain of ubiquinone whose length varies between organisms.
homodimeric decaprenyl diphosphate synthase complex
A heterotetrameric complex located in the mitochondrial inner membrane that possesses polyprenyl diphosphate synthase activity involved in the synthesis of the isoprenoid chain of ubiquinone whose length varies between organisms. In S. pombe it is a heterotetramer of Dlp1 and Dps1.
heterotetrameric decaprenyl diphosphate synthase complex
The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal.
detection of fungal associated molecule
detection of fungus associated molecule
The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal.
detection of oomycetes associated molecule
The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
detection of LPS
Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane.
silicon efflux transporter activity
The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.
somite rostrocaudal axis specification
somite rostrocaudal polarity
Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism.
down regulation of host-seeking behavior
down-regulation of host-seeking behavior
downregulation of host-seeking behavior
inhibition of host-seeking behavior
negative regulation of host-seeking behaviour
Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism.
activation of host-seeking behavior
positive regulation of host-seeking behaviour
stimulation of host-seeking behavior
up regulation of host-seeking behavior
up-regulation of host-seeking behavior
upregulation of host-seeking behavior
Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.
peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity
peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase
Srx1
sulphiredoxin activity
The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
plastid protein anabolism
plastid protein biosynthesis
plastid protein formation
plastid protein synthesis
plastid protein translation
Unwinding of an RNA helix in the 5' to 3' direction, driven by ATP hydrolysis.
5\' to 3\' RNA helicase activity
ATP-dependent 5\' to 3\' RNA helicase activity
ATP-dependent 5\'-3\' RNA helicase activity
Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.
phosphatidylcholine:cardiolipin linoleoyltransferase
A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.
endoplasmic reticulum-dependent peroxisome organization
ER-dependent peroxisome biogenesis
ER-dependent peroxisome organisation
The portion of the plasma membrane surrounding a ruffle.
membrane ruffle
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
Golgi trans face membrane
trans Golgi network membrane
A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.
GLUT4 storage compartment
GSC
IRC
The directed movement of a B cell receptor into an immunological synapse.
B cell receptor translocation into immunological synapse
BCR translocation into immunological synapse
BCR transport into immunological synapse
The directed movement of a chemokine receptor out of a membrane raft.
chemokine receptor translocation out of membrane raft
chemokine receptor transport out of lipid raft
Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production.
down regulation of connective tissue growth factor production
down-regulation of connective tissue growth factor production
downregulation of connective tissue growth factor production
inhibition of connective tissue growth factor production
negative regulation of CCN2 production
negative regulation of connective tissue growth factor biosynthetic process
negative regulation of CTGF production
negative regulation of Fisp12 production
negative regulation of Hcs24 production
negative regulation of hypertrophic chondrocyte-specific gene product 24 production
negative regulation of IGFBP8 production
Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production.
down regulation of fractalkine production
down-regulation of fractalkine production
downregulation of fractalkine production
inhibition of fractalkine production
negative regulation of CX3CL1 biosynthesis
negative regulation of CX3CL1 production
negative regulation of fractalkine biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
down regulation of granulocyte macrophage colony-stimulating factor production
down-regulation of granulocyte macrophage colony-stimulating factor production
downregulation of granulocyte macrophage colony-stimulating factor production
inhibition of granulocyte macrophage colony-stimulating factor production
negative regulation of GM-CSF production
negative regulation of granulocyte macrophage colony stimulating factor production
negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production.
down regulation of hepatocyte growth factor production
down-regulation of hepatocyte growth factor production
downregulation of hepatocyte growth factor production
inhibition of hepatocyte growth factor production
negative regulation of hepatocyte growth factor biosynthetic process
negative regulation of HGF production
negative regulation of scatter factor production
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.
down regulation of interferon-alpha production
down-regulation of interferon-alpha production
downregulation of interferon-alpha production
inhibition of interferon-alpha production
negative regulation of interferon-alpha biosynthetic process
negative regulation of interferon-alpha secretion
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
down regulation of interferon-beta production
down-regulation of interferon-beta production
downregulation of interferon-beta production
inhibition of interferon-beta production
negative regulation of IFN-beta production
negative regulation of interferon-beta biosynthetic process
negative regulation of interferon-beta secretion