NothingMuch/GO-Terms huggingface dataset:
The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.
protein polymer breakdown
protein polymer catabolic process
protein polymer catabolism
protein polymer degradation
The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.
protein tetramer assembly
protein tetramer biosynthesis
protein tetramer biosynthetic process
protein tetramer formation
The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.
beta-glucan metabolism
The chemical reactions and pathways resulting in the formation of beta-glucans.
beta-glucan anabolism
beta-glucan biosynthesis
beta-glucan formation
beta-glucan synthesis
The chemical reactions and pathways resulting in the breakdown of beta-glucans.
beta-glucan breakdown
beta-glucan catabolism
beta-glucan degradation
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
chromosome organisation
chromosome organization and biogenesis
DNA condensation
DNA packaging
maintenance of genome integrity
nuclear genome maintenance
The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.
cell wall polysaccharide anabolism
cell wall polysaccharide formation
cell wall polysaccharide synthesis
chitin- and beta-glucan-containing cell wall polysaccharide biosynthetic process
Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
regulation of calcium ion (Ca2+) mobilization
regulation of calcium mobilization
regulation of cytoplasmic release of sequestered calcium ion (Ca2+)
regulation of cytoplasmic release of stored calcium ion (Ca2+)
regulation of release of sequestered calcium ion (Ca2+)
regulation of release of stored calcium ion (Ca2+)
regulation of release of stored calcium ion (Ca2+) into cytoplasm
regulation of release of stored calcium ion (Ca2+) into cytosol
Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
down regulation of release of sequestered calcium ion into cytosol
down-regulation of release of sequestered calcium ion into cytosol
downregulation of release of sequestered calcium ion into cytosol
inhibition of release of sequestered calcium ion into cytosol
negative regulation of calcium ion (Ca2+) mobilization
negative regulation of calcium mobilization
negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)
negative regulation of cytoplasmic release of stored calcium ion (Ca2+)
negative regulation of cytosolic release of sequestered calcium ion (Ca2+)
negative regulation of cytosolic release of stored calcium ion (Ca2+)
negative regulation of release of sequestered calcium ion (Ca2+)
negative regulation of release of sequestered calcium ion into cytoplasm
negative regulation of release of stored calcium ion (Ca2+)
negative regulation of release of stored calcium ion (Ca2+) into cytoplasm
negative regulation of release of stored calcium ion (Ca2+) into cytosol
Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
activation of release of sequestered calcium ion into cytosol
positive regulation of calcium ion (Ca2+) mobilization
positive regulation of calcium mobilization
positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)
positive regulation of cytoplasmic release of stored calcium ion (Ca2+)
positive regulation of cytosolic release of sequestered calcium ion (Ca2+)
positive regulation of cytosolic release of stored calcium ion (Ca2+)
positive regulation of release of sequestered calcium ion (Ca2+)
positive regulation of release of sequestered calcium ion into cytoplasm
positive regulation of release of stored calcium ion (Ca2+)
positive regulation of release of stored calcium ion (Ca2+) into cytoplasm
positive regulation of release of stored calcium ion (Ca2+) into cytosol
stimulation of release of sequestered calcium ion into cytosol
up regulation of release of sequestered calcium ion into cytosol
up-regulation of release of sequestered calcium ion into cytosol
upregulation of release of sequestered calcium ion into cytosol
Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
regulation of calcium ion (Ca2+) retention
regulation of calcium ion (Ca2+) sequestering
regulation of calcium ion (Ca2+) sequestration
regulation of calcium ion (Ca2+) storage
regulation of retention of calcium ion (Ca2+)
regulation of sequestering of calcium ion (Ca2+)
regulation of sequestration of calcium ion (Ca2+)
regulation of storage of calcium ion (Ca2+)
Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
down regulation of sequestering of calcium ion
down-regulation of sequestering of calcium ion
downregulation of sequestering of calcium ion
inhibition of sequestering of calcium ion
negative regulation of calcium ion (Ca2+) retention
negative regulation of calcium ion (Ca2+) sequestering
negative regulation of calcium ion (Ca2+) sequestration
negative regulation of calcium ion (Ca2+) storage
negative regulation of retention of calcium ion (Ca2+)
negative regulation of sequestering of calcium ion (Ca2+)
negative regulation of sequestration of calcium ion (Ca2+)
negative regulation of storage of calcium ion (Ca2+)
Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
activation of sequestering of calcium ion
positive regulation of calcium ion (Ca2+) retention
positive regulation of calcium ion (Ca2+) sequestering
positive regulation of calcium ion (Ca2+) sequestration
positive regulation of calcium ion (Ca2+) storage
positive regulation of retention of calcium ion (Ca2+)
positive regulation of sequestering of calcium ion (Ca2+)
positive regulation of sequestration of calcium ion (Ca2+)
positive regulation of storage of calcium ion (Ca2+)
stimulation of sequestering of calcium ion
up regulation of sequestering of calcium ion
up-regulation of sequestering of calcium ion
upregulation of sequestering of calcium ion
The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
cell cortex of cell end
The region at the end of the longest axis of a cylindrical or elongated cell.
cell end
Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
NAD or NADH binding
NAD+ or NADH binding
nicotinamide adenine dinucleotide binding
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
protein homotetramer assembly
protein homotetramer biosynthesis
protein homotetramer biosynthetic process
protein homotetramer formation
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
protein heterooligomer assembly
protein heterooligomer biosynthesis
protein heterooligomer biosynthetic process
protein heterooligomer formation
The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.
NPC assembly
nuclear pore assembly
nuclear pore biogenesis
nuclear pore biosynthesis
nuclear pore complex biogenesis
nuclear pore complex biosynthesis
nuclear pore complex formation
nuclear pore formation
The directed movement of the spindle to a specific location in the cell.
establishment of spindle localisation
spindle positioning
Any process that set the alignment of spindle relative to other cellular structures.
orienting of spindle
spindle orientation
The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.
establishment of meiotic spindle localisation
meiotic spindle positioning
spindle positioning during meiosis
spindle positioning involved in meiotic cell cycle
The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
centrosome replication
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.
SPB maturation
SPB organization
spindle pole body maturation
spindle pole body organisation
spindle pole body organization and biogenesis
The directed movement of a chromosome to a specific location.
chromosome positioning
establishment of chromosome localisation
The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
chromatid release
rDNA separation
The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.
chromosome migration to spindle pole
chromosome movement
chromosome movement to spindle pole
The process in which sister chromatids are physically detached from each other during mitosis.
chromosome separation during mitosis
mitotic chromosome separation
mitotic sister chromatid resolution
sister chromatid separation during mitosis
The process in which chromosomes are physically detached from each other during meiosis.
chromosome separation during meiosis
meiotic chromosome resolution
A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
chromosome congression
A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
metaphase plate congression during meiosis
The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in mitosis.
attachment of spindle microtubules to kinetochore during mitosis
attachment of spindle microtubules to kinetochore involved in mitosis
attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation
attachment of spindle microtubules to mitotic chromosome
mitotic bipolar attachment
The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis.
attachment of spindle microtubules to kinetochore during meiosis
attachment of spindle microtubules to kinetochore during meiotic chromosome segregation
attachment of spindle microtubules to meiotic chromosome
The cell cycle phase, following G1, during which DNA synthesis takes place.
S-phase
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
meiosis
The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.
karyostasis
resting phase
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.
M phase of meiotic cell cycle
The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.
interphase of meiotic cell cycle
The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.
interphase of mitotic cell cycle
The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs.
meiotic nuclear envelope reassembly
Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
hydrolase regulator
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
transferase regulator
Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
lyase regulator
Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
ligase regulator
Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
oxidoreductase regulator
Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
3\',5\' cyclic nucleotide phosphodiesterase regulator
3\',5\'-cyclic-AMP phosphodiesterase regulator
cAMP phosphodiesterase regulator
phosphodiesterase regulator
regulation of 3\',5\' cyclic nucleotide phosphodiesterase activity
regulation of 3\',5\'-cyclic-AMP phosphodiesterase activity
regulation of cAMP phosphodiesterase activity
regulation of cGMP phosphodiesterase activity
regulation of cyclic nucleotide phosphodiesterase activity
Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.
activation of hydrolase activity
hydrolase activator
stimulation of hydrolase activity
up regulation of hydrolase activity
up-regulation of hydrolase activity
upregulation of hydrolase activity
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
down regulation of hydrolase activity
down-regulation of hydrolase activity
downregulation of hydrolase activity
hydrolase inhibitor
inhibition of hydrolase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
activation of transferase activity
stimulation of transferase activity
transferase activator
up regulation of transferase activity
up-regulation of transferase activity
upregulation of transferase activity
Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
down regulation of transferase activity
down-regulation of transferase activity
downregulation of transferase activity
inhibition of transferase activity
transferase inhibitor
Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
activation of lyase activity
lyase activator
stimulation of lyase activity
up regulation of lyase activity
up-regulation of lyase activity
upregulation of lyase activity
Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
down regulation of lyase activity
down-regulation of lyase activity
downregulation of lyase activity
inhibition of lyase activity
lyase inhibitor
Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
activation of ligase activity
ligase activator
stimulation of ligase activity
up regulation of ligase activity
up-regulation of ligase activity
upregulation of ligase activity
Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
activation of oxidoreductase activity
oxidoreductase activator
ribonucleotide reductase activating enzyme activity
stimulation of oxidoreductase activity
up regulation of oxidoreductase activity
up-regulation of oxidoreductase activity
upregulation of oxidoreductase activity
Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
down regulation of oxidoreductase activity
down-regulation of oxidoreductase activity
downregulation of oxidoreductase activity
inhibition of oxidoreductase activity
oxidoreductase inhibitor
Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.
addition of ethanolamine phosphate to mannose of GPI precursor
ethanolamine phosphate transferase activity
EtN-P transferase activity
phosphoethanolamine transferase activity
The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
centromere and kinetochore complex maturation
centromere/kinetochore complex maturation
chromosome-kinetochore attachment
kinetochore formation
NMS complex assembly
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
kinetochore organisation
kinetochore organization and biogenesis
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
response to glucocorticoid stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.
response to mineralocorticoid stimulus
Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
regulation of nerve growth factor receptor signaling pathway
regulation of nerve growth factor receptor signalling pathway
regulation of NGF receptor signaling pathway
regulation of NGF receptor signalling pathway
Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
alpha-actinin 1 binding
alpha-actinin 4 binding
nonmuscle alpha-actinin binding
Binding to a Bcl-2 homology (BH) protein domain. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains.
Bcl-2 homology domain binding
Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
apoptosis of neuronal cells
apoptosis of neurons
neuron apoptosis
neuron programmed cell death by apoptosis
neuronal cell apoptosis
neuronal cell programmed cell death by apoptosis
programmed cell death of neuronal cells by apoptosis
programmed cell death of neurons by apoptosis
programmed cell death, neuronal cells
programmed cell death, neurons
A MAPK cascade that starts with the activation of a stress-activated MAP kinase cascade.
MAPK11 cascade
MAPK12 cascade
MAPK13 cascade
MAPK14 cascade
SAPK cascade
stress-activated MAPK signaling pathway
stress-activated MAPK signalling pathway
stress-activated MAPKKK cascade
stress-activated MAPKKK signaling pathway
stress-activated MAPKKK signalling pathway