NothingMuch/GO-Terms huggingface dataset:
Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor.
B lymphocyte positive selection
B-cell positive selection
B-lymphocyte positive selection
The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
histamine production involved in acute inflammatory response
The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
serotonin production involved in acute inflammatory response
Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.
B lymphocyte negative selection
B-cell negative selection
B-lymphocyte negative selection
The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.
T lymphocyte lineage commitment
T-cell lineage commitment
T-lymphocyte lineage commitment
The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
CD4-positive, CD25-positive, alpha-beta regulatory T cell development
CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation
CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation
CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation
The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell.
alpha-beta T lymphocyte lineage commitment
alpha-beta T-cell lineage commitment
alpha-beta T-lymphocyte lineage commitment
A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
immune cell activation during immune response
leucocyte activation during immune response
leukocyte activation during immune response
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.
cytokine biosynthetic process involved in immune response
cytokine production during immune response
cytokine secretion during immune response
cytokine secretion involved in immune response
Any process that contributes to cytokine production by a B cell.
B lymphocyte cytokine production
B-cell cytokine production
B-lymphocyte cytokine production
Any process that contributes to cytokine production by a T cell.
T lymphocyte cytokine production
T-cell cytokine production
T-lymphocyte cytokine production
Any process that contributes to cytokine production by a natural killer cell.
NK cell cytokine production
The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
antibody production
immunoglobulin biosynthetic process
immunoglobulin secretion
The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
antibody production during immune response
antibody secretion during immune response
immunoglobulin biosynthetic process involved in immune response
immunoglobulin production during immune response
immunoglobulin production involved in immune response
immunoglobulin production involved in immunoglobulin mediated immune response
immunoglobulin secretion involved in immune response
Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
regulation of glandular kallikrein-kinin cascade
An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.
immune response in MALT
immune response in mucosal-associated lymphoid tissue
immune response in urogenital tract
Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules.
immune response in GALT
The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels.
lysosomal enzyme production involved in acute inflammatory response
production of lysosomal enzymes involved in acute inflammatory response
production of lysosomal enzymes involved in inflammatory response
Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).
oral tolerance
tolerance induction in GALT
An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids.
immune response in NALT
Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT).
tolerance induction in MALT
The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.
antigen sampling in MALT
antigen transport in MALT
antigen transport in mucosal-associated lymphoid tissue
The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.
antigen sampling by M cells in MALT
The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
T lymphocyte mediated cytotoxicity directed against tumor cell target
T-cell mediated cytotoxicity directed against tumor cell target
T-lymphocyte mediated cytotoxicity directed against tumor cell target
The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
NK cell mediated cytotoxicity directed against tumor cell target
The synthesis and release of immunoglobulin in the mucosal tissue.
antibody production in mucosal tissue
The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.
peptide antigen processing and presentation via MHC class Ib
The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a cell, leading to the activation or perpetuation of an immune response.
activation of immune response by cell surface receptor signaling pathway
immune response-activating cell surface receptor signalling pathway
The series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.
complement receptor mediated signalling pathway
immune response-regulating cell surface receptor signalling pathway
The series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
Fc receptor mediated stimulatory signalling pathway
Fc-receptor mediated stimulatory signaling pathway
An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
immune response-regulating cell surface receptor signalling pathway involved in phagocytosis
phagocytosis triggered by activation of immune response cell surface activating receptor
The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
production of cellular mediator of immune response
The regulated release of histamine by a cell as part of an inflammatory response.
histamine secretion involved in acute inflammatory response
The regulated release of serotonin by a cell as part of an inflammatory response.
serotonin release involved in inflammatory response
serotonin secretion involved in acute inflammatory response
Any process involved in the carrying out of an immune response by a leukocyte.
cell-mediated immune response
cellular immune response
immune cell effector process
immune cell mediated immunity
leucocyte immune effector process
leucocyte mediated immunity
leukocyte immune effector process
Any process involved in the carrying out of an immune response by a myeloid leukocyte.
myeloid leucocyte immune effector process
myeloid leucocyte mediated immunity
myeloid leukocyte immune effector process
Any process involved in the carrying out of an immune response by a lymphocyte.
cell-mediated immunity
cellular immune response
The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
B lymphocyte antigen processing and presentation
B-cell antigen processing and presentation
B-lymphocyte antigen processing and presentation
Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.
peripheral B lymphocyte tolerance induction
peripheral B-cell tolerance induction
peripheral B-lymphocyte tolerance induction
The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.
B lymphocyte receptor editing
B-cell receptor editing
B-lymphocyte receptor editing
Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells.
peripheral B lymphocyte anergy
peripheral B-cell anergy
peripheral B-lymphocyte anergy
The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.
peripheral B lymphocyte deletion
peripheral B-cell deletion
peripheral B-lymphocyte deletion
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
circulating antibody mediated immune response
circulating immunoglobulin mediated immune response
humoral defence mechanism
humoral immune response mediated by circulating antibody
Any process involved in the carrying out of an immune response by a T cell.
cell-mediated immunity
cellular immune response
T lymphocyte mediated immunity
T-cell mediated immunity
T-lymphocyte mediated immunity
The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
T lymphocyte antigen processing and presentation
T-cell antigen processing and presentation
T-lymphocyte antigen processing and presentation
Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus.
peripheral T lymphocyte tolerance induction
peripheral T-cell tolerance induction
peripheral T-lymphocyte tolerance induction
Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.
immune response-dependent tolerance induction
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
peptide antigen processing and presentation via MHC class I
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
endogenous peptide antigen processing and presentation via MHC class Ib
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
exogenous peptide antigen processing and presentation via MHC class Ib
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.
exogenous peptide antigen processing and presentation
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
endogenous peptide antigen processing and presentation
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.
endogenous peptide antigen processing and presentation via MHC class I via ER pathway
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
peptide antigen processing and presentation via MHC class II
The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.
peptide or polysaccharide antigen processing and presentation of via MHC class II
The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.
polysaccharide antigen processing and presentation via MHC class II
Tolerance induction of B cells in the bone marrow.
central B lymphocyte tolerance induction
central B-cell tolerance induction
central B-lymphocyte tolerance induction
A process involving any mechanism for tolerance induction in B cells.
B lymphocyte tolerance induction
B-cell tolerance induction
B-lymphocyte tolerance induction
Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.
B lymphocyte anergy
B-cell anergy
B-lymphocyte anergy
The apoptotic death of B cells which is part of B cell tolerance induction.
B lymphocyte deletion
B-cell deletion
B-lymphocyte deletion
A process involving any mechanism for tolerance induction in T cells.
T lymphocyte tolerance induction
T-cell tolerance induction
T-lymphocyte tolerance induction
Tolerance induction of natural killer cells.
NK cell tolerance induction
The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
immune cell differentiation
leucocyte differentiation
The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.
immune cell migration during immune response
immune cell trafficking during immune response
leucocyte migration during immune response
leucocyte trafficking during immune response
leukocyte trafficking during immune response
The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.
immune cell migration during inflammatory response
immune cell trafficking during inflammatory response
leucocyte migration during inflammatory response
leucocyte trafficking during inflammatory response
leukocyte migration during inflammatory response
leukocyte trafficking during inflammatory response
An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
hypersensitivity response
The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.
production of cellular mediator of acute inflammation
production of molecular mediator involved in acute inflammatory response
The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
cytokine production involved in acute inflammatory response
A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.
oxidative burst during acute inflammatory response
production of reactive oxygen species during acute inflammatory response
respiratory burst involved in acute inflammatory response
The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels.
arachidonic acid metabolite production involved in acute inflammatory response
arachidonic acid metabolite production involved in inflammatory response
production of arachidonic acid metabolites involved in acute inflammatory response
production of arachidonic acid metabolites involved in inflammatory response
The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
leukotriene production involved in acute inflammatory response
The somatic process that results in the generation of sequence diversity of T cell receptor genes.
somatic diversification of TCR genes
The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
pro-T lymphocyte differentiation
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.
myeloid leucocyte differentiation
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
platelet exocytosis
Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.
down regulation of antigen processing and presentation
down-regulation of antigen processing and presentation
downregulation of antigen processing and presentation
inhibition of antigen processing and presentation
Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.
activation of antigen processing and presentation
stimulation of antigen processing and presentation
up regulation of antigen processing and presentation
up-regulation of antigen processing and presentation
upregulation of antigen processing and presentation
Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
regulation of peptide or polysaccharide antigen processing and presentation via MHC class II
Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II
Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II
stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
regulation of peptide antigen processing and presentation
Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
down regulation of antigen processing and presentation of peptide antigen
down-regulation of antigen processing and presentation of peptide antigen
downregulation of antigen processing and presentation of peptide antigen
inhibition of antigen processing and presentation of peptide antigen
negative regulation of peptide antigen processing and presentation
Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
activation of antigen processing and presentation of peptide antigen
positive regulation of peptide antigen processing and presentation
stimulation of antigen processing and presentation of peptide antigen
up regulation of antigen processing and presentation of peptide antigen
up-regulation of antigen processing and presentation of peptide antigen
upregulation of antigen processing and presentation of peptide antigen
Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
regulation of peptide antigen processing and presentation via MHC class II
Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
regulation of peptide antigen processing and presentation via MHC class I