NothingMuch/GO-Terms huggingface dataset:
The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.
ADP-L-glycero-beta-D-manno-heptose anabolism
ADP-L-glycero-beta-D-manno-heptose biosynthesis
ADP-L-glycero-beta-D-manno-heptose formation
ADP-L-glycero-beta-D-manno-heptose synthesis
The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.
1,6-anhydro-N-acetyl-beta-muramate breakdown
1,6-anhydro-N-acetyl-beta-muramate catabolic process
1,6-anhydro-N-acetyl-beta-muramate catabolism
1,6-anhydro-N-acetyl-beta-muramate degradation
1,6-anhydro-N-acetyl-beta-muramic acid breakdown
1,6-anhydro-N-acetyl-beta-muramic acid catabolism
1,6-anhydro-N-acetyl-beta-muramic acid degradation
1,6-anhydro-N-acetylmuramate breakdown
1,6-anhydro-N-acetylmuramate catabolic process
1,6-anhydro-N-acetylmuramate catabolism
1,6-anhydro-N-acetylmuramate degradation
1,6-anhydro-N-acetylmuramic acid breakdown
1,6-anhydro-N-acetylmuramic acid catabolic process
1,6-anhydro-N-acetylmuramic acid catabolism
1,6-anhydro-N-acetylmuramic acid degradation
A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V.
PCI-coagulation factor V complex
plasma serine protease inhibitor-coagulation factor V complex
protein C inhibitor-F5 complex
serpin A5-coagulation factor V complex
SERPINA5-coagulation factor V complex
A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa.
PCI-coagulation factor Xa complex
plasma serine protease inhibitor-coagulation factor Xa complex
serpin A5-coagulation factor Xa complex
SERPINA5-coagulation factor Xa complex
A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI.
PCI-coagulation factor XI complex
plasma serine protease inhibitor-coagulation factor XI complex
protein C inhibitor-F11 complex
serpin A5-coagulation factor XI complex
SERPINA5-coagulation factor XI complex
The process in which calcium salts are deposited into the calcareous tooth structure known as dentin.
dentine mineralization
A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um.
apoptotic bleb
apoptotic vesicle
The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect.
goosebump reflex
horripilation
piloerection
A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.
membrane tetraspanin-enriched microdomain
TEM
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.
activation of caspase activity
activation of metacaspase activity
A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud.
bud dormancy
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
cellular response to GnRH
cellular response to gonadotrophin-releasing hormone
Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
positive regulation of lysosome membrane permeability
Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
negative regulation of lysosome membrane permeability
Binding to guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.
5\'-ppGpp-3\' binding
A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2.
PBF complex
PBF transcription complex
PCB binding factor complex
pombe cell cycle box binding factor complex
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus.
K+ facilitation of cell motility
potassium ion facilitation of cell motility
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.
Ca2+ facilitation of cell motility
calcium ion facilitation of cell motility
The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
hematopoietic stem cell homing
hemopoietic stem cell migration to bone marrow
progenitor cell homing
Binding to epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin.
catechin gallate binding
EGCG binding
The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
leukotriene B4 anabolism
leukotriene B4 biosynthesis
leukotriene B4 formation
leukotriene B4 synthesis
LTB4 anabolism
LTB4 biosynthesis
LTB4 formation
LTB4 synthesis
Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.
(R)-3-hydroxybutyrate transmembrane transporter activity
3-hydroxybutanoic acid transmembrane transporter activity
Catalysis of the reaction: leukotriene B4 + NADP+ = 12-oxo-leukotriene B4 + NADPH + H+.
leukotriene B4 12-hydroxydehydrogenase activity
Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + reduced  = 20-oxo-leukotriene B4 + H+ + 2 H2O + oxidized .
20-hydroxy-leukotriene B4 omega-oxidase activity
20-hydroxy-leukotriene B4 omega-oxidation
Catalysis of the reaction: 5-HETE + NADP+ = 5-oxo-ETE + NADPH + H+.
5(S)-HETE dehydrogenase activity
5-HETE dehydrogenase activity
5-hydroxy-eicosatetraenoic acid dehydrogenase activity
Catalysis of the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.
phenylacetyl-CoA epoxidase activity
phenylacetyl-CoA monooxygenase activity
ring 1,2-phenylacetyl-CoA epoxidase activity
The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.
P450 omega-hydroxylase pathway
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate.
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity
2-trans,6-trans-farnesyl diphosphate activity
A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.
protein localisation to bud neck
protein localization to cellular bud neck
A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell.
cellular ammonia homeostasis
cellular ammonium homeostasis
Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.
histamine secretion mediated by IgE antibody
Ig-mediated histamine release
The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.
antibody-mediated agglutination
The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.
antibody-mediated neutralization
The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolopyrimidine-5-carbonitrile or preQo.
7-cyano-7-deazaguanine anabolism
7-cyano-7-deazaguanine biosynthesis
7-cyano-7-deazaguanine formation
7-cyano-7-deazaguanine synthesis
The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).
alpha-ribazole metabolism
A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
renal phosphate absorption
The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.
\'de novo\' XMP anabolism
\'de novo\' XMP biosynthesis
\'de novo\' XMP formation
\'de novo\' XMP synthesis
The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.
morphine anabolism
morphine biosynthesis
morphine formation
morphine synthesis
Any process that modulates the size of the nucleus.
regulation of nuclear size
regulation of nuclear volume
Binding to a 7SK small nuclear RNA (7SK snRNA).
7SK small nuclear RNA binding
The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid).
glycolate membrane transport
Any process that prevents the activation of an inactive cysteine-type endopeptidase.
inhibition of caspase activity
prevention of caspase activity
prevention of cysteine-type endopeptidase activity
A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.
necrosome
TNFR1 complex II
Tnfr1-CII
A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane.
translocation and assembly module protein complex
Binding to a toxin to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.
toxin-antitoxin pair type I binding
toxin-antitoxin pair type II binding
The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC.
perinucleolar region
A protein complex capable of condensing two 2Fe-2S clusters into one 4Fe-4S center in the cytoplasm and nucleus. In humans it consists of MMS19, CIAO1, CIAO2A/CIAO2B, CIAO3. MMS19, CIAO1 and CIAO2A/CIAO2B form a tight 'core' complex, whereas CIAO3 is an 'external' component of this complex.
CIA complex
CIA targeting complex
cytosolic iron-sulfur protein assembly complex
Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell.
stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.
response to bronchodilator agent
response to broncholytic agent
Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + NAD+ + H2O = histone H3 L-lysine (position 18) + 2''-O-acetyl-ADP-D-ribose + nicotinamide. This reaction transfers an acetyl group attached to a lysine residue in H3K18 to NAD, producing nicotinamide.
NAD-dependent histone deacetylase activity (H3-K18 specific)
NAD-dependent histone H3-K18 deacetylase activity
NAD-dependent histone H3K18 deacetylase activity
A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated.
MCM4/6/7 complex
The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
dorsal interneuron caudal axon projection
The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
dorsal interneuron rostral axon projection
Catalysis of the reaction: dIDP + H2O = dIMP + H+ + phosphate.
deoxyinosine-diphosphatase activity
A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment).
necrotic cell death in response to starvation
The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CCL19 production
EBI1 ligand chemokine production
ELC production
macrophage inflammatory protein-3-beta production
MIP-3-beta production
The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CCL21 production
The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CXCL12 production
The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CXCL13 production
The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CXCL16 production
The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome.
TERRA transcription
The series of molecular signals initiated by interleukin-32 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
IL-32-mediated signaling pathway
IL-32-mediated signalling pathway
interleukin-32-mediated signalling pathway
Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy.
GCI
Papp-Lantos body
A glass-like, pale intracellular inclusion.
pale body
Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.
brainstem Lewy body
Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments.
LBHI
Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.
flame-shaped neurofibrillary tangle
star-shaped neurofibrillary tangle
A network of fine tubules in the vicinity of the Golgi complex and around the centriole.
coated tip
An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans.
MAC
mitochondrial adhaerens complex
The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol.
copper ion import into ascospore-type prospore
copper ion transport into forespores
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in).
succinate:hydrogen symporter activity
The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.
induction of dormancy
A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles.
MVB-tubule complex
Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered.
active zone dense projection
pre-synaptic active zone dense projection
A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.
protein localization to linear eisosome
Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans.
glial limiting endfoot
A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP.
gamma interferon-activated inhibitor of translation complex
IFN-gamma-activated inhibitor of translation complex
Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide.
mesaxon of Schwann cell
Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath.
terminal loop of Schwann cell
Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones.
type III terminal button
A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes.
cerebellar mossy fiber to granule cell synapse  syngo_official_label
Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.
rod photoreceptor apoptotic process
Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.
cone photoreceptor apoptotic process
Any of the two layers of lipid molecules that constitute a membrane.
membrane leaflet
The directed movement of a synaptic vesicle or vesicles to a specific location.
establishment of synaptic vesicle localisation
A postsynaptic specialization that is part of a neuromuscular junction.
muscle cell postsynaptic density
muscle fiber postsynaptic density
Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
sympathetic neurite extension
sympathetic neuron process extension
sympathetic neuron protrusion extension
sympathetic neuronal cell projection extension
The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.
sympathetic neurite guidance
sympathetic neuron process guidance
sympathetic neuron protrusion guidance
sympathetic neuronal cell projection guidance