NothingMuch/GO-Terms huggingface dataset:
The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
retinol metabolism
vitamin A1 alcohol metabolic process
vitamin A1 alcohol metabolism
vitamin A1 metabolic process
vitamin A1 metabolism
The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.
primary oocyte nucleus
Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide.
formyl-L-methionyl peptide amidohydrolase activity
PDF activity
polypeptide deformylase activity
Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface.
glycogen particle
Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment.
behavioural response to starvation
Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.
flavin reductase activity
FMN reductase (NADPH) activity
NADPH dehydrogenase (riboflavin) activity
NADPH-dependent FMN reductase activity
NADPH-FMN reductase activity
NADPH-riboflavin oxidoreductase activity
NADPH-riboflavin reductase activity
NADPH-specific FMN reductase activity
NADPH:riboflavin oxidoreductase activity
reduced-riboflavin:NADP+ oxidoreductase activity
riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase activity
riboflavin mononucleotide reductase activity
riboflavine mononucleotide reductase activity
Binding to an antigen peptide.
endogenous peptide antigen binding
exogenous peptide antigen binding
Binding to a T cell receptor, the antigen-recognizing receptor on the surface of T cells.
T lymphocyte receptor binding
T-cell receptor binding
T-lymphocyte receptor binding
TCR binding
Binding to a CD70, a receptor found on the surface of most activated B cells and some activated T cells.
CD27 receptor activity
CD27L binding
Binding to CD154, a receptor found on the surface of some activated lymphocytes.
CD40 receptor activity
CD40L binding
The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.
paclitaxel anabolism
paclitaxel biosynthesis
paclitaxel formation
paclitaxel metabolic process
paclitaxel metabolism
paclitaxel synthesis
taxol biosynthesis
taxol biosynthetic process
taxol metabolic process
taxol metabolism
The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.
PHB biosynthesis
PHB biosynthetic process
poly-hydroxybutyrate anabolism
poly-hydroxybutyrate biosynthesis
poly-hydroxybutyrate formation
poly-hydroxybutyrate synthesis
The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males.
copulatory plug biosynthesis
copulatory plug deposition
copulatory plug formation
mating plug deposition
Any process that results in a change in the behavior of an organism as a result of deprivation of water.
behavioral response to drought
behavioral response to thirst
behavioural response to water deprivation
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
positive regulation of cholesterol homeostasis
regulation of cholesterol homeostasis
Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
activation of hair cycle
stimulation of hair cycle
up regulation of hair cycle
up-regulation of hair cycle
upregulation of hair cycle
Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
down regulation of hair cycle
down-regulation of hair cycle
downregulation of hair cycle
inhibition of hair cycle
The resting phase of hair cycle.
hair resting phase
Combining with ecdysis-triggering hormone to initiate a change in cell activity.
ecdysis-triggering hormone binding
ETH receptor
Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs).
JUNKKKK activity
Binding to the lateral surface of major histocompatibility complex class II molecules.
major histocompatibility complex class II protein binding, via lateral surface
Binding to the antigen binding groove of major histocompatibility complex class II molecules.
major histocompatibility complex class II protein binding, via antigen binding groove
Any process that restricts, stops or prevents a cell from specifying into an endoderm cell.
down regulation of endodermal cell fate specification
down-regulation of endodermal cell fate specification
downregulation of endodermal cell fate specification
inhibition of endodermal cell fate specification
negative regulation of endoderm cell fate specification
suppression of endoderm cell fate
suppression of endodermal cell fate
Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell.
down regulation of ectodermal cell fate specification
down-regulation of ectodermal cell fate specification
downregulation of ectodermal cell fate specification
inhibition of ectodermal cell fate specification
negative regulation of ectoderm cell fate specification
suppression of ectoderm cell fate
suppression of ectodermal cell fate
The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed.
auditory hair cell fate determination
Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.
down regulation of cone cell fate specification
down-regulation of cone cell fate specification
downregulation of cone cell fate specification
inhibition of cone cell fate specification
suppression of cone cell fate
Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation.
down regulation of crystal cell differentiation
down-regulation of crystal cell differentiation
downregulation of crystal cell differentiation
inhibition of crystal cell differentiation
Any process that activates or increases the frequency, rate or extent of crystal cell differentiation.
activation of crystal cell differentiation
stimulation of crystal cell differentiation
up regulation of crystal cell differentiation
up-regulation of crystal cell differentiation
upregulation of crystal cell differentiation
A G protein-coupled receptor signaling pathway initiated by follicle-stimulating hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
follicle stimulating hormone signaling pathway
follicle stimulating hormone signalling pathway
follicle-stimulating hormone signalling pathway
Female behaviors associated with the care and rearing of offspring.
maternal behaviour
Male behaviors associated with the care and rearing offspring.
paternal behaviour
Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.
Tim9-Tim10 complex
Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.
IMP
mitochondrion inner membrane peptidase complex
A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12.
mitochondrial inner membrane protein insertion complex
mitochondrial protein translocase complex
Tim22 complex
The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region.
alpha-beta T lymphocyte activation by superantigen
alpha-beta T-cell activation by superantigen
alpha-beta T-lymphocyte activation by superantigen
A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the outer kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
condensed nuclear chromosome kinetochore-associated DASH complex
Dam1 complex
DDD complex
Duo1p-Dam1p-Dad1p complex
Catalysis of the reaction: ATP + NADH = ADP + 2 H+ + NADPH.
ATP:NADH 2\'-phosphotransferase activity
DPNH kinase activity
reduced diphosphopyridine nucleotide kinase activity
reduced nicotinamide adenine dinucleotide kinase (phosphorylating)
The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism.
exogenous antibiotic breakdown
exogenous antibiotic catabolism
exogenous antibiotic degradation
The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.
endogenous antibiotic breakdown
endogenous antibiotic catabolism
endogenous antibiotic degradation
Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season.
aestivation
The chemical reactions and pathways resulting in the formation of a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
very-long-chain fatty acid anabolism
very-long-chain fatty acid biosynthesis
very-long-chain fatty acid biosynthetic process
very-long-chain fatty acid formation
very-long-chain fatty acid synthesis
An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor.
GPIT complex
The chemical reactions and pathways resulting in the formation of ATP driven by transport of protons across a plasma membrane to generate an electrochemical gradient (proton-motive force).
ATP synthesis coupled proton transport
plasma membrane ATP synthesis coupled proton transport
Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
3 tRNase activity
3\' tRNA processing endoribonuclease activity
3\' tRNase activity
ribonuclease Z activity
RNase Z activity
tRNA 3 endonuclease activity
tRNA 3\' endonuclease activity
tRNAse Z
The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
mRNA transcription from Pol II promoter
mRNA transcription from RNA polymerase II promoter
The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter.
5S class rRNA transcription from RNA polymerase III type 1 promoter
5S rRNA transcription
The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase.
rRNA transcription from plastid promoter
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
snRNA transcription from Pol III promoter
snRNA transcription from RNA polymerase III promoter
The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.
tRNA transcription from Pol III promoter
tRNA transcription from RNA polymerase III promoter
Binding to an identical protein to form a homodimer.
dimerization activity
Binding to a nuclear vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes.
calciferol receptor binding
VDR binding
vitamin D receptor binding
The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
pheromone anabolism
pheromone biosynthesis
pheromone formation
pheromone synthesis
The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
pheromone breakdown
pheromone catabolism
pheromone degradation
Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity.
frizzled receptor activity
frizzled-2 receptor activity
Wnt-activated receptor activity
The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds.
pyridoxal anabolism
pyridoxal biosynthesis
pyridoxal formation
pyridoxal synthesis
A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum.
transporter associated with antigen presentation
Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.
defence response to pathogenic protozoa
defence response to protozoa
defence response to protozoon
defense response to pathogenic protozoa
defense response to protozoa
defense response to protozoan, incompatible interaction
defense response to protozoon
resistance response to pathogenic protozoa
resistance response to pathogenic protozoan
The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate.
D-glucarate anabolism
D-glucarate biosynthesis
D-glucarate formation
D-glucarate synthesis
saccharate biosynthesis
saccharate biosynthetic process
The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate.
D-glucarate breakdown
D-glucarate catabolism
D-glucarate degradation
saccharate catabolic process
saccharate catabolism
The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate.
D-glucuronate anabolism
D-glucuronate biosynthesis
D-glucuronate formation
D-glucuronate synthesis
The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.
D-xylose anabolism
D-xylose biosynthesis
D-xylose formation
D-xylose synthesis
The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.
L-sorbose anabolism
L-sorbose biosynthesis
L-sorbose formation
L-sorbose synthesis
The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose.
L-sorbose breakdown
L-sorbose catabolism
L-sorbose degradation
The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
4-allyl-2-methoxyphenol biosynthesis
4-allyl-2-methoxyphenol biosynthetic process
eugenic acid biosynthesis
eugenic acid biosynthetic process
eugenol anabolism
eugenol biosynthesis
eugenol formation
eugenol synthesis
The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
4-allyl-2-methoxyphenol catabolic process
4-allyl-2-methoxyphenol catabolism
eugenic acid catabolic process
eugenic acid catabolism
eugenol breakdown
eugenol catabolism
eugenol degradation
The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).
chrysobactin anabolism
chrysobactin biosynthesis
chrysobactin biosynthetic process, peptide formation
chrysobactin biosynthetic process, peptide modification
chrysobactin formation
chrysobactin synthesis
The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).
chrysobactin breakdown
chrysobactin catabolism
chrysobactin degradation
The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore.
achromobactin anabolism
achromobactin biosynthesis
achromobactin formation
achromobactin synthesis
The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore.
achromobactin breakdown
achromobactin catabolism
achromobactin degradation
The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
pyochelin anabolism
pyochelin biosynthesis
pyochelin biosynthetic process, peptide formation
pyochelin biosynthetic process, peptide modification
pyochelin formation
pyochelin synthesis
The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
pyochelin breakdown
pyochelin catabolism
pyochelin degradation
The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other.
D-glucarate transport
The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other.
D-glucuronate transport
The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other.
D-galactonate transport
The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.
L-arabinose transport
The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other.
chloramphenicol transport
Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other.
chloramphenicol transporter activity
Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other.
polymyxin transporter activity
Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other.
fosmidomycin transporter activity
The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other.
arabinan transport
The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative.
9-cis-retinoic acid anabolism
9-cis-retinoic acid biosynthesis
9-cis-retinoic acid formation
9-cis-retinoic acid synthesis
The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.
xanthine transmembrane transport
The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other.
3-(3-hydroxyphenyl)propionic acid transport
3-hydroxyphenylpropionic acid transport
m-hydroxyphenylpropionic acid transport
Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses.
NMU binding
Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other.
benzoate transporter activity
Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other.
3-(3-hydroxyphenyl)propionic acid transporter activity
3-hydroxyphenylpropionic acid transporter activity
m-hydroxyphenylpropionic acid transporter activity
A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
ferrichrome transport
Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
ferrichrome transporter activity
The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
enterochelin transport
Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.
enterobactin transporter activity
enterochelin transporter activity
Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other.
chrysobactin transporter activity
Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other.
achromobactin transporter activity
Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid.
D-alanine transporter activity
Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid.
D-serine permease activity
D-serine transporter activity
The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, across a membrane.
maltodextrin transport
Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
antimonite porter activity
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out).
antimonite-transporting ATPase activity
ATP-dependent antimonite transporter activity