NothingMuch/GO-Terms huggingface dataset:
Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
RNA hairpin binding
RNA hairpin loop binding
Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation.
maintenance of BBB
maintenance of blood/brain barrier
The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
bacterial entry into host cell
invasion of bacteria into host cell
Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
purine NTP binding
The specific behavior of an organism in response to a novel environment or stimulus.
exploration behaviour
exploratory behavior
exploratory behaviour
open-field behavior
Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle.
cargo loading into clathrin-coated vesicle
The series of molecular signals initiated by interleukin-18 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
interleukin-18-mediated signalling pathway
The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
MAL-dependent toll-like receptor signaling pathway
MyD88 adapter-like dependent toll-like receptor signaling pathway
TIRAP-dependent TLR signaling pathway
TIRAP-dependent toll-like receptor signalling pathway
The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR signaling pathway
TRIF-dependent TLR signaling pathway
TRIF-dependent toll-like receptor signalling pathway
The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
TRAM-dependent TLR signaling pathway
TRAM-dependent toll-like receptor signalling pathway
The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
oligopeptide membrane transport
Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
oligopeptide transporter activity
The process in which a tricarboxylic acid is transported across a membrane.
tricarboxylic acid membrane transport
The series of molecular signals initiated by a ligand binding to toll-like receptor 15.
TLR15 signaling pathway
toll-like receptor 15 signalling pathway
The series of molecular signals initiated by a ligand binding to toll-like receptor 21.
TLR21 signaling pathway
toll-like receptor 21 signalling pathway
The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.
helper T-cell extravasation
T-helper cell extravasation
The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.
helper T-cell diapedesis
T-helper cell diapedesis
The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
Th1 cell extravasation
The series of molecular signals initiated by macrophage migration inhibitory factor binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
macrophage migration inhibitory factor signalling pathway
MIF signaling pathway
The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
hemopoietic stem cell migration
The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4).
IL-4-dependent isotype switching to IgE isotypes
The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Th1 cell activation
The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Th2 cell activation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.
response to NO2
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
intraflagellar anterograde transport
The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.
intraflagellar retrograde transport
The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation.
CD24 anabolism
CD24 biosynthesis
CD24 formation
CD24 synthesis
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
sodium ion membrane transport
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
response to hepatocyte growth factor stimulus
response to HGF stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
cellular response to HGF stimulus
The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism.
envenomation resulting in modification of morphology or physiology of other organism
envenomation resulting in modulation of process in other organism
Any process that contributes to cytokine production by a T-helper 1 cell.
Th1 cell cytokine production
Any process that contributes to cytokine production by a T-helper 2 cell.
Th2 cell cytokine production
A process in which a symbiont moves from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
migration in host through an epithelial cell layer
migration of symbiont within host by transepithelial trafficking
symbiont-mediated migration through host transepithelium
transepithelial migration of symbiont in host
transmigration of symbiont in host
A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.
mRNP granule
RNA granule
RNP granule
The series of molecular signals initiated by interleukin-4 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
IL-4-mediated signaling pathway
interleukin-4-mediated signalling pathway
The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.
insulin secretion involved in cellular response to glucose
The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.
CD80 anabolism
CD80 biosynthesis
CD80 formation
CD80 synthesis
The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.
CD86 anabolism
CD86 biosynthesis
CD86 formation
CD86 synthesis
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.
CD4-positive, alpha beta T cell costimulation
The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.
cell migration involved in metanephric kidney development
The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.
metanephric mesenchyme chemotaxis
The series of molecular signals initiated a ligand binding to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
alphaPDGF receptor signaling pathway
PDGF receptor-alpha signaling pathway
PDGFR-alpha signaling pathway
platelet-derived growth factor receptor-alpha signalling pathway
The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
betaPDGF receptor signaling pathway
PDGF receptor-beta signaling pathway
PDGFR-beta signaling pathway
platelet-derived growth factor receptor-beta signalling pathway
Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
mitochondrial membrane permeability transition
mitochondrial membrane permeabilization
mitochondrial permeability transition
MPT
positive regulation of transport across mitochondrial membrane
Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
mitochondrial membrane impermeability
mitochondrial membrane impermeabilization
negative regulation of transport across mitochondrial membrane
The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).
adrenal gland cortex development
Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
VE formation
vitelline envelope formation
zona pellucida assembly
ZP assembly
A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
vitelline membrane
zona pellucida
The process in which an organism effects a change that affects blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
modulation by organism of blood clotting in other organism
modulation by organism of blood coagulation in other organism
modulation of blood coagulation in another organism
modulation of blood coagulation in other organism
perturbation of blood clotting in another organism
regulation by organism of blood clotting in other organism
regulation of blood clotting in other organism
regulation of blood coagulation in other organism
Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
induction of blood clotting in another organism
positive regulation by organism of blood clotting in other organism
positive regulation by organism of blood coagulation in other organism
positive regulation of blood clotting in other organism
positive regulation of blood coagulation in another organism
positive regulation of blood coagulation in other organism
Any process that modulates the amount of urine excreted from the body over a unit of time.
regulation of urinary volume
regulation of urine flow
Any process that increases the amount of urine excreted from the body over a unit of time.
diuresis
elevation of urinary volume
increase in urine flow
Any process that decreases the amount of urine excreted from the body over a unit of time.
antidiuresis
decrease in urine flow
reduction of urinary volume
Any process that increases the amount of sodium excreted in urine over a unit of time.
natriuresis
The process in which an organism effects a change in the structure or processes of another organism.
modification of morphology or physiology of other organism
modulation of process of other organism
regulation of morphology of other organism
regulation of morphology or physiology of other organism
regulation of physiological process of other organism
regulation of physiology of other organism
A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules.
chromosomal crossover
interchromosomal DNA recombination
interstrand DNA recombination
reciprocal DNA recombination
The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants.
palmatine metabolism
The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid.
berbamunine metabolism
The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.
indole alkaloid metabolism
The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.
indole alkaloid anabolism
indole alkaloid biosynthesis
indole alkaloid formation
indole alkaloid synthesis
The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid.
ergot alkaloid metabolism
The chemical reactions and pathways resulting in the formation of an ergot alkaloid.
ergot alkaloid anabolism
ergot alkaloid biosynthesis
ergot alkaloid formation
ergot alkaloid synthesis
The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs.
growing cell end
A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.
new cell end
non-growing cell end
A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.
old growing cell end
The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.
cloacal development
The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.
fallopian tube epithelium development
Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina.
horizontal cell localisation
horizontal cell positioning
laminar positioning of retinal horizontal cell
retinal horizontal cell positioning
The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin.
eosinophil cell fate commitment
A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p.
GATOR complex
SEA complex
The series of molecular signals initiated by a ligand binding to a glial cell-derived neurotrophic factor receptor.
GDNF receptor signaling pathway
glial cell derived neurotrophic factor receptor signaling pathway
glial cell line-derived neurotrophic factor receptor signalling pathway
glial cell-derived neurotrophic factor receptor signalling pathway
The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.
2\'-Deoxyinosine 5\'-triphosphate metabolic process
2\'-Deoxyinosine-5\'-triphosphate metabolic process
deoxyinosine 5\'-triphosphate metabolic process
deoxyinosine triphosphate (2\'-deoxyinosine 5\'-triphosphate) metabolic process
dITP metabolism
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
response to K+ ion
response to potassium
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
cellular response to K+ ion
cellular response to potassium
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
cilial transition zone
cilium transition zone
connecting cilium
The series of molecular signals initiated by a ligand binding to a nucleotide-binding domain, leucine rich repeat containing receptor (NLR), and ending with the regulation of a downstream cellular process. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number.
NLR signaling pathway
NOD-like receptor signaling pathway
nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway
nucleotide-binding domain, leucine rich repeat containing receptor signal transduction
nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway
nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway
The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
lactate membrane transport
The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
maintenance of centromeric meiotic sister chromatin cohesion
maintenance of meiotic sister chromatin cohesion at centromere
maintenance of sister chromatin cohesion at centromere at meiosis I
The directed movement of lactate across a plasma membrane.
lactate plasma membrane transport
The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
amacrine neuron differentiation
The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.
defecation behavior
defecation cycle
defecation motor program
DMP
The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.
vascular smooth muscle cell differentiation
VSMC differentiation
The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
ejection from host
ejection from host cell
exit from host
host cell exit
The process in which an organism effects a change that affects platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
modulation by organism of platelet aggregation in other organism
modulation of platelet aggregation in another organism
modulation of platelet aggregation in other organism
regulation of platelet aggregation in other organism