NothingMuch/GO-Terms huggingface dataset:
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.
1,6-alpha-mannosyltransferase activity
Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.
single-stranded DNA specific endodeoxyribonuclease activity
ssDNA-specific endodeoxyribonuclease activity
Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.
regulation of recombination within rDNA repeats
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
microtubule sliding involved in mitotic spindle elongation
spindle elongation during mitosis
The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.
malt sugar metabolic process
malt sugar metabolism
maltose metabolism
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
50S ribosomal subunit assembly
60S ribosomal subunit assembly
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
30S ribosomal subunit assembly
40S ribosomal subunit assembly
The chemical reactions and pathways involving a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
very long chain fatty acid metabolic process
very-long-chain fatty acid metabolic process
very-long-chain fatty acid metabolism
The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
transition metal transport
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
autophagic vacuole assembly
autophagic vacuole formation
autophagosome biosynthesis
autophagosome formation
PAS formation
Binding to a transfer RNA.
base pairing with tRNA
The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
citrulline metabolism
The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
ribosomal subunit export from cell nucleus
ribosomal subunit export out of nucleus
ribosomal subunit transport from nucleus to cytoplasm
ribosomal subunit-nucleus export
ribosome export from nucleus
The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.
50S ribosomal subunit export from nucleus
60S ribosomal subunit export from nucleus
ribosomal large subunit export from cell nucleus
ribosomal large subunit export out of nucleus
ribosomal large subunit transport from nucleus to cytoplasm
ribosomal large subunit-nucleus export
The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.
30S ribosomal subunit export from nucleus
40S ribosomal subunit export from nucleus
ribosomal small subunit export from cell nucleus
ribosomal small subunit export out of nucleus
ribosomal small subunit transport from nucleus to cytoplasm
ribosomal small subunit-nucleus export
Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.
fatty-acyl binding
fatty-acyl-coenzyme A binding
Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.
histidine/arginine/lysine/ornithine porter activity
L-ornithine transporter activity
The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.
mitotic chromosome segregation
mitotic sister-chromatid adhesion release
A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.
cell cycle checkpoint
G1/S checkpoint
G1/S transition checkpoint
G2/M checkpoint
G2/M transition checkpoint
signal transduction involved in cell cycle checkpoint
signal transduction involved in G2/M transition checkpoint
A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
DNA replication checkpoint
signal transduction involved in DNA replication checkpoint
A signal transduction process that contributes to a DNA damage checkpoint.
DNA damage checkpoint
DNA damage response, signal transduction resulting in cell cycle arrest
signal transduction involved in DNA damage checkpoint
Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
regulation of CDK activity
regulation of cyclin-dependent protein kinase activity
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
mitotic G2/M transition
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.
M phase of mitotic cell cycle
M-phase of mitotic cell cycle
Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
S-adenosyl methionine permease activity
S-adenosyl methionine transporter activity
S-adenosylmethionine permease activity
S-adenosylmethionine transmembrane transporter activity
S-adenosylmethionine transporter activity
SAM transmembrane transporter activity
The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.
sulfur amino acid metabolism
sulphur amino acid metabolic process
sulphur amino acid metabolism
The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
sulfur amino acid anabolism
sulfur amino acid biosynthesis
sulfur amino acid formation
sulfur amino acid synthesis
sulphur amino acid biosynthesis
sulphur amino acid biosynthetic process
The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
sulfur amino acid breakdown
sulfur amino acid catabolism
sulfur amino acid degradation
sulphur amino acid catabolic process
sulphur amino acid catabolism
Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.
sulfur amino acid transporter activity
sulphur amino acid transmembrane transporter activity
sulphur amino acid transporter activity
The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
sulphur amino acid transport
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor
sulphate assimilation
sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
fumarate dehydrogenase activity
fumarate reductase activity
fumaric hydrogenase activity
succinate oxidoreductase activity
succinic acid dehydrogenase activity
succinic dehydrogenase activity
succinodehydrogenase activity
succinyl dehydrogenase activity
The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
histidine anabolism
histidine biosynthesis
histidine biosynthetic process
histidine formation
histidine synthesis
Any complex formed of proteins that act in nucleotide-excision repair.
UvrB-UvrC complex
UvrBC complex
One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p).
NEF3 complex
A protein complex that possesses histone deacetylase activity.
HDAC complex
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I.
RNA polymerase I transcription factor complex
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
down regulation of global transcription from RNA polymerase II promoter
down regulation of transcription from RNA polymerase II promoter
down-regulation of global transcription from RNA polymerase II promoter
down-regulation of transcription from RNA polymerase II promoter
downregulation of global transcription from RNA polymerase II promoter
downregulation of transcription from RNA polymerase II promoter
inhibition of global transcription from RNA polymerase II promoter
inhibition of transcription from RNA polymerase II promoter
negative regulation of gene-specific transcription from RNA polymerase II promoter
negative regulation of global transcription from Pol II promoter
negative regulation of transcription from Pol II promoter
negative regulation of transcription from RNA polymerase II promoter
negative regulation of transcription from RNA polymerase II promoter, global
A protein complex that possesses histone acetyltransferase activity.
histone acetylase complex
The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs.
cell-cell adhesion involved in flocculation
cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction
co-flocculation
coflocculation
coflocculation via lectin-mannose interaction
coflocculation via protein-carbohydrate interaction
flocculation via cell wall protein-carbohydrate interaction
flocculation via extracellular polymer
A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
establishment of spindle orientation during mitosis
establishment of spindle orientation involved in mitotic cell cycle
mitotic spindle orientation
orienting of mitotic spindle
A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.
alpha-1,6-mannosyltransferase complex
The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.
Golgi apparatus cis cisterna
The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.
late Golgi
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
Golgi apparatus membrane
A motor activity that generates movement along a microfilament, driven by ATP hydrolysis.
actin filament motor activity
actin-activated ATPase activity
actin-dependent ATPase activity
actin-filament motor activity
muscle motor activity
myosin ATPase activity
Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
SNAP receptor binding
The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.
rRNA editing
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
histidyl-aspartyl phosphorelay
An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
ERK/MAPK cascade
MAP kinase cascade
MAP kinase kinase kinase cascade
MAPK signal transduction
MAPK signaling
MAPK signalling
MAPKKK cascade
MAPKKK cascade during sporulation
mitogen-activated protein kinase cascade
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
3\'-5\' exoribonuclease activity
3\'-5\'-exoribonuclease activity
A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
eukaryotic exosome multienzyme ribonuclease complex
nuclear exosome (ribonuclease complex)
nuclear exosome multienzyme ribonuclease complex
A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
cytoplasmic exosome (ribonuclease complex)
cytoplasmic exosome multienzyme ribonuclease complex
prokaryotic exosome multienzyme ribonuclease complex
A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
exosome (ribonucleasease complex)
exosome multienzyme ribonuclease complex
Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.
18S rRNA dimethylase activity
dimethyladenosine transferase activity
S-adenosylmethionine-6-N\', N\'-adenosyl(rRNA) dimethyltransferase activity
Binding to a DNA sequence encoding a ribosomal RNA.
ribosomal DNA binding
The formation of heterochromatin at ribosomal DNA, characterized by the modified histone H3K9me3.
chromatin silencing at rDNA
chromatin silencing at ribosomal DNA
heterochromatic silencing at rDNA
rDNA chromatin silencing
rDNA heterochromatin assembly
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
mRNA breakdown, nonsense-mediated decay
mRNA catabolic process, nonsense-mediated
mRNA catabolism, nonsense-mediated
mRNA degradation, nonsense-mediated decay
nonsense-mediated mRNA decay
nuclear mRNA catabolic process, nonsense-mediated decay
A MAPK cascade that specifically ensures the maintenance and regulation of cellular structure in response to external signals, including plasma membrane stretching or cell wall alteration, to coordinate cellular responses such as growth, differentiation, and stress adaptation, thereby preserving cell integrity. Contains the  SLT2 (S.cerevisiae)/Pmk1 (S.pombe) MAP kinase or orthologs.
cell integrity MAPK pathway
cell wall integrity MAPK cascade
CWI pathway
Mpk1 cascade
Pmk1 MAPK cell integrity signaling
Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway
PMK1-MAPK signal transduction pathway
Slt2 cascade
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
polyubiquitin
protein polyubiquitinylation
protein polyubiquitylation
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
meiotic spindle organisation
meiotic spindle organization and biogenesis
meiotic spindle stabilization
spindle organization during meiosis
The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
vacuolar hydrogen ion-transporting ATPase V0 domain
The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
vacuolar hydrogen ion-transporting ATPase V1 domain
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
microtubule cytoskeleton organisation
microtubule cytoskeleton organization and biogenesis
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
nuclear interphase chromosome
The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.
spliceosome assembly
The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism.
allantoin metabolism
The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
allantoin breakdown
allantoin catabolism
allantoin degradation
Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.
acetonitrilase activity
benzonitrilase activity
nitrile aminohydrolase activity
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
mitochondrial division
mitochondrial proliferation
Binding to a peroxisomal targeting sequence, a sequence of amino acids within a protein that acts as a signal for the localization of a protein into the peroxisome.
peroxisome targeting signal receptor
PTS binding
PTS receptor
The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.
murein metabolic process
murein metabolism
peptidoglycan metabolism
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
glycan biosynthesis
glycan biosynthetic process
polysaccharide anabolism
polysaccharide biosynthesis
polysaccharide formation
polysaccharide synthesis
The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
multicellular organismal polysaccharide catabolic process
polysaccharide breakdown
polysaccharide catabolism
polysaccharide degradation
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
mitosis
A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.
M-phase
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
karyokinesis
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
cytokinesis after mitosis
The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.
bud site selection/establishment of cell polarity
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
deadenylation-dependent mRNA decay
mRNA breakdown, deadenylation-dependent decay
mRNA catabolic process, deadenylation-dependent
mRNA catabolic process, deadenylylation-dependent
mRNA catabolism, deadenylation-dependent
mRNA catabolism, deadenylylation-dependent
mRNA degradation, deadenylation-dependent decay
nuclear mRNA catabolic process, deadenylation-dependent decay
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
3\' to 5\' mRNA deadenylation
mRNA deadenylation
nuclear mRNA poly(A) tail shortening
Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
deadenylation-dependent decapping of nuclear mRNA
deadenylylation-dependent decapping
Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe2+-siderophore + electron acceptor.
ferric chelate reductase activity
iron chelate reductase activity
The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi.
retrograde (vesicle recycling within Golgi) transport
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
response to active oxygen species
response to AOS
response to reactive oxidative species
response to reactive oxygen intermediate
response to ROI
response to ROS