NothingMuch/GO-Terms huggingface dataset:
Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.
modulation of mast cell degranulation in other organism
regulation of mast cell degranulation in other organism
The regulated release of parathyroid hormone into the circulatory system.
parathormone secretion
parathyrin secretion
PTH secretion
Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
disruption of blood coagulation in other organism
down-regulation of blood coagulation in other organism
downregulation of blood coagulation in other organism
inhibition of blood coagulation in other organism
negative regulation of blood clotting in other organism
negative regulation of blood coagulation in another organism
negative regulation of blood coagulation in other organism
suppression of blood clotting in another organism
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.
response to social isolation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.
response to immobilisation stress
response to restraint stress
Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism.
modulation of calcium channel activity in other organism
Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism.
down-regulation of calcium channel activity in other organism
downregulation of calcium channel activity in other organism
inhibition of calcium channel activity in other organism
negative regulation of calcium channel activity in other organism
Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
down-regulation of voltage-gated calcium channel activity in other organism
downregulation of voltage-gated calcium channel activity in other organism
inhibition of voltage-gated calcium channel activity in other organism
negative regulation of voltage gated calcium channel activity in other organism
negative regulation of voltage-dependent calcium channel activity in other organism
negative regulation of voltage-gated calcium channel activity in other organism
negative regulation of voltage-sensitive calcium channel activity in other organism
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.
cellular response to vascular endothelial growth factor
cellular response to VEGF
cellular response to VEGFA
cellular response to VEGFB
The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix.
cytoplasmic RNA import into mitochondrion
nuclear-encoded RNA import into mitochondrion
The regulated release of any corticosteroid hormone into the circulatory system.
corticosteroid secretion
The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals.
oestrogen secretion
The regulated release of estradiol into the circulatory system.
oestradiol secretion
The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system.
androst-4-ene-3,17-dione secretion
The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system.
3beta-hydroxyandrost-5-en-17-one secretion
dehydroisoandrosterone secretion
DHEA secretion
The regulated release of estrone into the circulatory system.
3-hydroxy-1,3,5(10)-estratrien-17-one secretion
folliculin secretion
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
response to IL-13
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
cellular response to IL-13
The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.
COPI vesicle budding
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
response to misfolded or unfolded protein
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
cellular response to misfolded or unfolded protein
A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.
Activating protein 1 complex
AP-1 complex
AP1 complex
transcription factor AP1 complex
The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.
endoderm cell differentiation
The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.
cartilage cell proliferation
chondrocyte cell proliferation
The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.
sinew development
The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.
muscle attachment cell differentiation
tenocyte differentiation
Binding to a pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
protein-coding primary transcript binding
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
response to M-CSF
response to macrophage colony-stimulating factor stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
cellular response to M-CSF stimulus
cellular response to macrophage colony-stimulating factor
Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.
protein glutamine N-methylase activity
protein glutamine N-methyltransferase activity
A process in which a protein is transported to, or maintained in, a location within an endosome.
protein localisation in endosome
protein localization in endosome
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.
response to IL-3
The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.
knee morphogenesis
leg joint morphogenesis
The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.
neural crest cell emigration
neural crest cell individualization
neural crest cell segregation
The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
osteoclast cell development
The chemical reactions and pathways involving the polyphenol, curcumin.
(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process
(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism
curcumin metabolism
diferuloylmethane metabolic process
diferuloylmethane metabolism
turmeric yellow metabolic process
turmeric yellow metabolism
Binding to a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
long chain fatty acid binding
A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.
protein localisation to trailing edge
The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.
muscle cell attraction
muscle cell chemotaxis towards tendon cell
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodeling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
basal body
cilial basal body
cilium basal body
kinetosome
microtubule basal body
The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light.
light dependent chlorophyll biosynthetic process
light-dependent chlorophyll anabolism
light-dependent chlorophyll biosynthesis
light-dependent chlorophyll formation
light-dependent chlorophyll synthesis
The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light.
light independent chlorophyll biosynthetic process
light-independent chlorophyll anabolism
light-independent chlorophyll biosynthesis
light-independent chlorophyll formation
light-independent chlorophyll synthesis
Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation.
indirect ossification
Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.
cleavage furrow positioning
Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.
cleavage furrow contraction
The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
leukotriene breakdown
leukotriene catabolism
leukotriene degradation
The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
LTB4 metabolism
The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component.
Kdo2-lipid A metabolism
The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).
4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate metabolic process
undecaprenyl phosphate alpha-L-Ara4N metabolism
The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a very long-chain fatty-acyl group. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
very long-chain fatty acyl CoA metabolic process
very long-chain fatty acyl-CoA metabolism
The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
medium-chain fatty acyl CoA metabolic process
medium-chain fatty acyl-CoA metabolism
The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
fatty-acyl-CoA breakdown
fatty-acyl-CoA catabolism
fatty-acyl-CoA degradation
A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
HA cable assembly
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
response to PDGF stimulus
response to platelet-derived growth factor stimulus
A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
sperm cilium
sperm tail
Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.
acylglycerol acyl-chain remodelling
glyceride acyl-chain remodeling
The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain.
oxytocin biosynthesis
oxytocin secretion
A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
phenotypic dimorphism
The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
asperthecin metabolism
The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
asperthecin biosynthesis
asperthecin formation
asperthecin synthesis
A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
muscle arm
myocyte projection
myopodia
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
cellular protein modification process
process resulting in protein modification
protein modification
The process of an actomyosin ring getting smaller in diameter.
contractile ring constriction
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.
response to hematopoietic growth factor KL
response to KIT ligand
response to SCF
response to stem cell factor stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.
cellular response to hematopoietic growth factor KL
cellular response to KIT ligand
cellular response to KITLG
cellular response to SCF
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
MVB organization
The growth of colonies in filamentous chains of cells into a substrate.
invasive growth
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.
response to HMG-CoA reductase inhibitor
response to hydroxymethylglutaryl-CoA reductase inhibitor
Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes.
TBC
The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.
serine autophosphorylation
The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer.
trans-autophosphorylation
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
response to lowered oxygen levels
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
cellular response to lowered oxygen levels
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.
cellular response to raised oxygen levels
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.
response to raised oxygen levels
Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.
ICL repair
A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell.
B cell receptor uptake of antigen
BCR endocytosis
BCR receptor internalization
The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
M-CSF production
The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees.
avascular cornea development
The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.
Apo-1 signaling pathway
CD95 signaling pathway
FAS ligand-Fas signaling pathway
Fas receptor signaling pathway
Fas-FasL signaling pathway
FasL signaling pathway
FasR signaling pathway
The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.
sodium export
sodium ion export
sodium ion export from cell
Any of the smallest contractile units of a myofibril (striated muscle fiber).
striated muscle filament
A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
pre-RC
pre-replication complex
The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
pre-RC assembly
pre-replication complex assembly
The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
C-C motif chemokine 20 production
CCL-20 production
CCL20 production
The controlled release of amylase from a cell.
amylase release