NothingMuch/GO-Terms huggingface dataset:
A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium.
mycelium developmental competence
A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signaling and metabolism, and in calcium signaling.
PFR
A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface.
multiciliation
multiciliogenesis
The elimination of urate salt or uric acid from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.
urate excretion
urate salt excretion
A membrane tubulation process occurring in an endosome membrane.
endosomal membrane tubulation
The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores.
sporangium formation
sporophore formation
Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection.
phage reversible adsorption
reversible bacteriophage attachment, binding of host cell surface receptor
The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell.
irreversible bacteriophage attachment, binding of host cell surface receptor
phage irreversible adsorption
Process by which virus heads and tails are attached to each other.
phage head tail joining
virus head-tail joining
The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full.
phage headful packaging
The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit.
virus terminase, large subunit
The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits.
major capsomere
major head protein
The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits.
minor capsomere
minor head protein
The basal end of the virus tail, which is used by the virus to attach to the host cell.
bacteriophage tail tip
The fibrous region of the virus tail used to scan, recognize and attach to the host cell.
bacteriophage tail fiber
Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached.
bacteriophage baseplate
tail structure
tail tip
The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm.
bacteriophage tail tube
The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm.
bacteriophage tail sheath
The tube of the non-contractile tails of some viruses.
bacteriophage tail shaft
Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.
cut-and-paste transposition
non-replicative transposition, DNA-mediated
Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition.
copy-and-paste transposition
replicative transposition, DNA-mediated
transpositional DNA genome replication
A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc).
autotransporter system complex
T5SS complex
The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins.
internal head protein
Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
positive regulation of D-loop biosynthesis
positive regulation of D-loop formation
positive regulation of Rad51-mediated strand invasion
Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation.
centriole amplification
de novo centriole assembly
de novo centriole assembly via deuterosome
deuterosomal basal body biogenesis
deuterosome pathway
deuterosome-mediated centriole biogenesis
multiciliation
multiciliogenesis
The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the lumen.
internal side of trans-Golgi network transport vesicle membrane
The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm.
external side of trans-Golgi network transport vesicle membrane
The side (leaflet) of the early endosome membrane that faces the lumen.
internal leaflet of early endosome membrane
internal side of early endosome membrane
The side (leaflet) of the late endosome membrane that faces the lumen.
internal leaflet of late endosome membrane
internal side of late endosome membrane
The side (leaflet) of the early endosome membrane that faces the cytoplasm.
external leaflet of early endosome membrane
external side of early endosome membrane
The side (leaflet) of the late endosome membrane that faces the cytoplasm.
external leaflet of late endosome membrane
external side of late endosome membrane
The side (leaflet) of the lysosomal membrane that faces the cytoplasm.
external leaflet of lysosomal membrane
external side of lysosomal membrane
The side (leaflet) of the lysosomal membrane that faces the lumen.
internal leaflet of lysosomal membrane
internal side of lysosomal membrane
Catalysis of the reaction: O-phosphoseryl-tRNA(Sec) + selenophosphoric acid + H2O => L-selenocysteinyl-tRNA(Sec) + 2 phosphoric acid.
O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase
O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase   {comment=EC:2.9.1.2}
phosphoseryl-selenocysteinyl-tRNA selenium transferase activity
SepSecS
Catalysis of the reaction: H+ + selenodiglutathione + NADPH = gluthathioselenol + glutathione + NADP+.
selenodiglutathione-disulfide reductase (NADP) activity
selenodiglutathione-disulfide reductase activity
Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+.
PAPSe reductase activity
A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere.
MIS18 complex
A protein complex that is capable of G protein-coupled serotonin receptor activity.
G-protein coupled serotonin receptor complex
A process by which a symbiont inhibits or disrupts the CRISPR-cas system of its host. Bacteria and archaea use CRISPR-Cas adaptive immune systems to defend themselves from infection by bacteriophages (phages), and phages have various mechanisms to counter the CRISPR-cas system.
anti-CRISPR
CRISPR-cas system evasion by virus
evasion by virus of CRISPR-cas system
inhibition of host CRISPR-cas system by virus
suppression of host CRISPR-cas system
Any process by which a virus inhibits DNA replication in its host cell. Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication.
inhibition of host DNA replication by virus
A process by which a virus improves the virulence of its host for that host's respective host. Common in but not limited to bacteriophages; also occurs in phage-bearing bacteria infecting plants or animals for example. Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production of exotoxins or provide protection against host immune defenses.
modulation of host virulence by virus
Maturation of a virion after separation from the host cell. Not all viruses mature after separation. In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection.
viral particle maturation
virus particle maturation
The process by which a virus switches on its replication cycle in an infected cell. The process is typically controlled by a genetic switch controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli.
Latency-replication switch
lytic switch
prophage induction
proviral induction
proviral switch
reactivation of latent virus
Any inositol 1,4,5-trisphosphate receptor activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
IP3 receptor activity involved in regulation of postsynaptic cytosolic calcium levels
The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol.
adenine import into cell
The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol.
copper cation import into cell
copper ion import into cell
high affinity copper ion transport
high affinity copper transport
high-affinity copper ion transport
The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space.
ferric ion import into cell
ferric iron import across cell outer membrane
ferric iron import into cell
ferric iron transmembrane transport
high affinity ferric iron transport
high-affinity ferric iron transmembrane transport
The directed movement of D-glucose from outside of a cell, across the plasma membrane and into the cytosol.
glucose import across plasma membrane
glucose import into cell
high affinity glucose import
The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol.
glutathione import into cell
glutathione uptake
The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol.
guanine import into cell
The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol.
malate import into cell
The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol.
malonate import into cell
malonic acid import into cell
The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol.
nickel cation import into cell
The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol.
pantothenate import
pantothenate import into cell
The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol.
succinate import into cell
A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA.
Dcp1-Dcp2 complex
The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
synchronous, calcium ion-dependent exocytosis of neurotransmitter
A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization.
tafi
thin aggregative fimbrae
The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface.
extracellular nucleation-precipitation pathway
Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress.
mechanically-gated potassium channel activity
The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium.
apical dendritic knob
A posttranscriptional gene silencing pathway that involves the cleavage of mRNAs in a non-gene-specific manner.
gene silencing by mRNA cleavage
mRNA cleavage involved in gene silencing
mRNA destabilization-mediated gene silencing
RNA interference, targeting of mRNA for destruction
targeting of mRNA for destruction involved in RNA interference
The portion of the plasma membrane surrounding a non-motile cilium.
nonmotile primary cilium membrane
The cytoplasmic component of the presynaptic endocytic zone.
cortex of presynaptic endocytic zone
A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms.
pedicel
podocyte foot process
secondary podocyte projection
Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane.
alpha-D-ribose-1-methylphosphonate-5-phosphate C-P-lyase (methane forming)
Binding to double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures.
miRNA duplex binding
A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes.
ER-vacuole membrane contact site
A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot.
glomerular visceral epithelial cell primary projection
podocyte major process
primary podocyte process
A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart.
HCN1 channel complex
HCN2 channel complex
HCN3 channel complex
HCN4 channel complex
K/Na hyperpolarization-activated channel 3 complex
K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex
K/Na hyperpolarization-activated cyclic nucleotide-gated channel 2 complex
K/Na hyperpolarization-activated cyclic nucleotide-gated channel 4 complex
K/Na hyperpolarization-activated cyclic nucleotide-gated channel complex
potassium/sodium hyperpolarization-activated channel 3 complex
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 complex
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 complex
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 tetramer
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel complex
The process in which a symbiont organism that stabilizes the its host tight cell-cell junctions, making them less dynamic. The tight junction is a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other, and plays a role in the inflammatory response of the host.
modification by symbiont of host tight cell-cell junction
stabilization of host tight cell-cell junction
A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse.
G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels  syngo_official_label
The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion.
neurotransmitter receptor insertion
The action of a molecule that contributes to the structural integrity of a presynaptic active zone.
structural constituent of active zone  syngo_official_label
Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
regulation of bundle of His cardiac muscle cell action potential
Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
regulation of SA node cardiac muscle cell action potential
regulation of SAN cardiac muscle cell action potential
regulation of sinoatrial node cardiac muscle cell action potential
regulation of sinus node cardiac muscle cell action potential
The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
atrial cardiac muscle cell depolarization
atrial depolarization
electrocardiogram PR interval
The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
electrocardiogram QRS complex
ventricular depolarization
The disruption by a symbiont of host cell wall peptidoglycans to allow entry into the host cell.
catabolism of host cell wall peptidoglycan by virus
degradation of host cell wall peptidoglycan by virus
degradation of host peptidoglycans during virus entry
disassembly by virus of host cell wall peptidoglycan
disruption by virus of host cell wall peptidoglycan during virus entry
The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation.
postsynaptic neurotransmitter receptor endosomal trafficking
The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse.
retrograde axon transport of mitochondria
The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse.
retrograde dendrite transport of mitochondria
The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.
dendritic transport of RNP complex
The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites.
dendritic transport of mRNA RNP complex
The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse.
anterograde dendritic transport of mRNA RNP complex
The portion of the extracellular matrix that lies within the synaptic cleft.
ECM of synaptic cleft
synaptic cleft ECM
The disruption by a symbiont of host cell envelope components to allow entry into the host cell.
disruption of host cell envelope during viral entry
The disruption by a symbiont of host cell wall lipopolysaccharides to allow entry into the host cell. For example a phage entering a Gram-negative bacterium may actively break down outer membrane lipopolysaccharides.
degradation of host cell envelope lipopolysaccharide during viral entry
degradation of host lipopolysaccharide during virus entry
disassembly by virus of outer membrane lipopolysaccharide during viral entry
disruption by virus of host envelope lipopolysaccharide during virus entry
The disruption by a symbiont of host cell capsule to allow entry into the host cell.
catabolism of host glycocalyx during viral entry
degradation of host capsule during virus entry
degradation of host glycocalyx during viral entry
disassembly of glycocalyx during viral entry
disruption of host cell glycocalyx during viral entry
symbiont entry into host cell by disruption of host cell capsule
Fusion of a viral membrane with the host cell outer membrane during viral entry.
fusion of viral membrane with host outer membrane
viral envelope fusion
viral envelope fusion with host outer membrane
viral penetration via membrane fusion
viral-cell fusion molecule activity
Entry of a symbiont's genome into the host cell through the host cell envelope via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath. Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope. Occurs in non-enveloped prokaryotic viruses.
viral contractile tail ejection system
viral genome ejection through host cell envelope, contractile tail mechanism
Entry of a symbiont's genome into the host cell through the host cell envelope via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm. Occurs in non-enveloped prokaryotic viruses.
viral genome ejection through host cell envelope, long flexible tail mechanism
viral long flexible tail ejection system
Entry of a symbiont's genome into the host cell through the host cell envelope via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties. Occurs in non-enveloped prokaryotic viruses.
viral genome ejection through host cell envelope, short tail mechanism
viral short tail ejection system