NothingMuch/GO-Terms huggingface dataset:
The process by which a symbiont breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the symbiont or its genome is released into the host cell.
entry of virus into host cell
phage translocation
viral entry into host cell
viral penetration
virion penetration
virion penetration into host cell
virus entry into host cell
Any virus-mediated process that modulates the levels of viral proteins in a cell.
regulation of viral protein levels
Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses.
capsomer
The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs).
spread of virus in multicellular host
spread of virus within multicellular host
viral spread within multicellular host
A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.
viral capsid envelopment
virion budding
virus budding
A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.
nuclear membrane viral budding
nuclear membrane viral budding during viral capsid envelopment
viral budding from nuclear membrane by viral capsid envelopment
viral budding from nuclear membrane during viral capsid envelopment
virus budding from nuclear membrane
virus budding from nuclear membrane by viral capsid envelopment
virus budding from nuclear membrane during viral capsid envelopment
Any viral process that results in the inhibition of host cell cytokine production.
negative regulation by virus of host cytokine production
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
protein amino acid autophosphorylation
The addition of tubulin heterodimers to one or both ends of a microtubule.
microtubule assembly
microtubule formation
The directed movement of a virus, or part of a virus, into, out of, or within a host cell.
viral transport
virion transport
The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.
capsid egress
egress of viral procapsid from host cell nucleus
nuclear egress
nuclear egress of viral procapsid
The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.
virion attachment, binding of host cell surface receptor
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.
down regulation of nucleocytoplasmic transport
down-regulation of nucleocytoplasmic transport
downregulation of nucleocytoplasmic transport
inhibition of nucleocytoplasmic transport
Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
activation of nucleocytoplasmic transport
stimulation of nucleocytoplasmic transport
up regulation of nucleocytoplasmic transport
up-regulation of nucleocytoplasmic transport
upregulation of nucleocytoplasmic transport
Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.
regulation of protein export from cell nucleus
regulation of protein export out of nucleus
regulation of protein transport from nucleus to cytoplasm
regulation of protein-nucleus export
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
activation of protein export from nucleus
positive regulation of protein export from cell nucleus
positive regulation of protein export out of nucleus
positive regulation of protein transport from nucleus to cytoplasm
positive regulation of protein-nucleus export
stimulation of protein export from nucleus
up regulation of protein export from nucleus
up-regulation of protein export from nucleus
upregulation of protein export from nucleus
Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.
regulation of RNA import into cell nucleus
regulation of RNA transport from cytoplasm to nucleus
regulation of RNA-nucleus import
Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.
regulation of RNA export from cell nucleus
regulation of RNA export out of nucleus
regulation of RNA transport from nucleus to cytoplasm
regulation of RNA-nucleus export
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.
down regulation of RNA export from nucleus
down-regulation of RNA export from nucleus
downregulation of RNA export from nucleus
inhibition of RNA export from nucleus
negative regulation of RNA export from cell nucleus
negative regulation of RNA export out of nucleus
negative regulation of RNA transport from nucleus to cytoplasm
negative regulation of RNA-nucleus export
Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm.
activation of RNA export from nucleus
positive regulation of RNA export from cell nucleus
positive regulation of RNA export out of nucleus
positive regulation of RNA transport from nucleus to cytoplasm
positive regulation of RNA-nucleus export
stimulation of RNA export from nucleus
up regulation of RNA export from nucleus
up-regulation of RNA export from nucleus
upregulation of RNA export from nucleus
The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota.
trisporic acid metabolism
The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
filopodia biosynthesis
filopodia formation
filopodium formation
The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.
bone remodelling
Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
regulation of bone remodelling
Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.
down regulation of bone remodeling
down-regulation of bone remodeling
downregulation of bone remodeling
inhibition of bone remodeling
negative regulation of bone remodelling
The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate.
phosphatidylinositol phosphate biosynthesis
phosphatidylinositol phosphate phosphorylation
phosphatidylinositol phosphorylation
phosphoinositide phosphorylation
PIP biosynthesis
PtdInsP biosynthesis
The process of removing one or more phosphate groups from a phosphatidylinositol.
phosphatidylinositol phosphate catabolic process
phosphatidylinositol phosphate dephosphorylation
phosphoinositide dephosphorylation
PIP catabolism
PtdInsP catabolism
PtdInsP dephosphorylation
Binding to a metal ion.
heavy metal binding
metal binding
Enables the transfer of metal ions from one side of a membrane to the other.
heavy metal ion porter activity
heavy metal ion transporter activity
heavy metal ion:hydrogen symporter activity
heavy metal-exporting ATPase activity
high affinity metal ion uptake transporter activity
low affinity metal ion uptake transporter activity
The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
quinolinate metabolism
Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
regulation of follicle stimulating hormone secretion
regulation of FSH secretion
The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.
follicle stimulating hormone secretion
follitropin secretion
FSH secretion
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
regulation of hormone anabolism
regulation of hormone biosynthesis
regulation of hormone formation
regulation of hormone synthesis
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
activation of hormone biosynthetic process
positive regulation of hormone anabolism
positive regulation of hormone biosynthesis
positive regulation of hormone formation
positive regulation of hormone synthesis
stimulation of hormone biosynthetic process
up regulation of hormone biosynthetic process
up-regulation of hormone biosynthetic process
upregulation of hormone biosynthetic process
Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.
activation of hormone secretion
stimulation of hormone secretion
up regulation of hormone secretion
up-regulation of hormone secretion
upregulation of hormone secretion
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.
down regulation of hormone secretion
down-regulation of hormone secretion
downregulation of hormone secretion
inhibition of hormone secretion
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
activation of lipid biosynthetic process
positive regulation of lipid anabolism
positive regulation of lipid biosynthesis
positive regulation of lipid formation
positive regulation of lipid synthesis
positive regulation of lipogenesis
stimulation of lipid biosynthetic process
up regulation of lipid biosynthetic process
up-regulation of lipid biosynthetic process
upregulation of lipid biosynthetic process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
regulation of lipid anabolism
regulation of lipid biosynthesis
regulation of lipid formation
regulation of lipid synthesis
regulation of lipogenesis
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.
response to actidione
The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
tetrahydrofolyl-(n) metabolic process
tetrahydrofolyl-(n) metabolism
tetrahydrofolylpolyglutamate metabolism
Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
regulation of mitochondrial envelope permeability
regulation of transport across mitochondrial membrane
Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.
porphyrin binding
The directed movement of substances within a cell.
single organism intracellular transport
single-organism intracellular transport
Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.
acyltransferase, acyl groups converted into alkyl on transfer
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage.
alpha(1,3)-fucosyltransferase activity
alpha-(1,3)-fucosyltransferase activity
alpha-1,3-fucosyltransferase activity
Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.
alpha(1,6)-fucosyltransferase activity
alpha-(1,6)-fucosyltransferase activity
alpha-1,6-fucosyltransferase activity
Binding to an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER.
endoplasmic reticulum retention sequence binding
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
conotoxin activity
down regulation of neurotransmitter secretion
down-regulation of neurotransmitter secretion
downregulation of neurotransmitter secretion
inhibition of neurotransmitter secretion
A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids.
channel-forming toxin activity
pore
pore-forming toxin activity
The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases.
pore biosynthesis
pore complex biogenesis
pore formation
pore-forming toxin activity
The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
cadystin metabolic process
cadystin metabolism
phytochelatin metabolism
The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases.
hydroxylysine metabolism
The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
fatty acyl CoA biosynthetic process
fatty-acyl-CoA anabolism
fatty-acyl-CoA biosynthesis
fatty-acyl-CoA formation
fatty-acyl-CoA synthesis
The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.
ketone body anabolism
ketone body biosynthesis
ketone body formation
ketone body synthesis
The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
ketolysis
ketone body breakdown
ketone body catabolism
ketone body degradation
utilization of ketone bodies
A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.
unconditional response
The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3\'-phosphoadenosine 5\'-phosphosulphate transport
adenosine 3\'-phosphate 5\'-phosphosulfate transport
PAPS transport
The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.
cytosol to ER transport
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of up to three methyl groups to the lysine residue at position 9 of the histone H3 protein.
histone H3K9 methylase activity
histone lysine N-methyltransferase activity (H3-K9 specific)
histone methylase activity (H3-K9 specific)
histone methyltransferase activity (H3-K9 specific)
histone-H3K9 methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group to the lysine residue at position 36 of the histone H3 protein.
histone H3K36 methylase activity
histone lysine N-methyltransferase activity (H3-K36 specific)
histone methylase activity (H3-K36 specific)
histone methyltransferase activity (H3-K36 specific)
histone-H3K36 methyltransferase activity
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group to the lysine residue at position 27 of the histone H3 protein.
histone H3K27 methylase activity
histone lysine N-methyltransferase activity (H3-K27 specific)
histone methylase activity (H3-K27 specific)
histone methylase activity (H3-K56 specific)
histone methyltransferase activity (H3-K27 specific)
histone-H3K27 methyltransferase activity
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
regulation of haemoglobin biosynthesis
regulation of haemoglobin biosynthetic process
regulation of hemoglobin anabolism
regulation of hemoglobin biosynthesis
regulation of hemoglobin formation
regulation of hemoglobin synthesis
Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y.
oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors
Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
3(17)alpha-hydroxysteroid dehydrogenase activity
3(or 17)-alpha-hydroxysteroid dehydrogenase activity
3(or 17)alpha-hydroxysteroid dehydrogenase activity
3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity
Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
disulfide reductase activity
insulin-glutathione transhydrogenase activity
NAD(P)H:protein-disulfide oxidoreductase activity
protein disulfide reductase (NAD(P)H) activity
protein disulfide reductase activity
protein disulphide reductase activity
protein-disulfide reductase (NAD(P)) activity
protein-disulfide reductase activity
protein-disulphide reductase activity
Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol.
GDP mannose-undecaprenyl phosphate mannosyltransferase activity
GDP-D-mannose:lipid phosphate transmannosylase activity
GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase activity
guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity
Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.
nucleoside-triphosphate diphosphatase activity
nucleoside-triphosphate diphosphohydrolase activity
nucleoside-triphosphate pyrophosphatase activity
The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
microtubule-based vesicle localization
The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
mitochondrial migration along microtubule
mitochondrial transport along microtubule
Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase
(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase
alpha-hydroxyglutarate dehydrogenase (NAD+ specific)
alpha-hydroxyglutarate dehydrogenase activity
alpha-hydroxyglutarate oxidoreductase activity
hydroxyglutaric dehydrogenase activity
L-alpha-hydroxyglutarate dehydrogenase activity
L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase
Catalysis of the reaction: 3',5'-cyclic GMP + H2O = GMP + H+.
3\',5\' cyclic-GMP phosphodiesterase activity
3\',5\'-cyclic-GMP 5\'-nucleotidohydrolase activity
cGMP phosphodiesterase activity
cGMP-PDE
cGMP-specific phosphodiesterase activity
cyclic 3\',5\'-GMP phosphodiesterase activity
cyclic GMP phosphodiesterase activity
cyclic guanosine 3\',5\'-monophosphate phosphodiesterase activity
cyclic guanosine 3\',5\'-phosphate phosphodiesterase activity
guanosine cyclic 3\',5\'-phosphate phosphodiesterase activity
Catalysis of the reaction: a (S)-hydroxynitrile = hydrogen cyanide + an aldehyde or ketone.
alpha-hydroxynitrile lyase activity
hydroxynitrilase activity
hydroxynitrile lyase activity
oxynitrilase activity
Catalysis of the reaction: a fatty acyl-CoA + H2O = a fatty acid + CoA + H+.
acyl coenzyme A hydrolase activity
acyl coenzyme A thioesterase activity
acyl-CoA hydrolase activity
acyl-CoA thioesterase activity
acyl-CoA thioesterase I activity
acyl-CoA thioesterase II activity
acyl-CoA thiolesterase activity
thioesterase B
thioesterase II
Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP.
adenine nucleotide deaminase activity
adenosine (phosphate) deaminase activity
adenosine-phosphate aminohydrolase activity
Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.
alanine--oxo-acid aminotransferase activity
alanine-keto acid aminotransferase activity
alanine-oxo acid aminotransferase activity
alanine-oxo-acid aminotransferase activity
L-alanine-alpha-keto acid aminotransferase activity
L-alanine:2-oxo-acid aminotransferase activity
leucine-alanine transaminase activity
Catalysis of the reaction: an L-amino acid = a D-amino acid.
L-amino acid racemase activity
Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid.
acetyl-CoA:D-amino-acid N-acetyltransferase activity
D-amino acid acetyltransferase activity
D-amino acid-alpha-N-acetyltransferase activity
Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H.
beta-D-glucose:NAD(P)+ 1-oxidoreductase activity
D-glucose dehydrogenase (NAD(P))
hexose phosphate dehydrogenase activity
Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.
D-hexose:oxygen 1-oxidoreductase activity
The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
antigen presentation, peptide antigen
peptide antigen processing and presentation