NothingMuch/GO-Terms huggingface dataset:
The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.
larval lymph gland arthropod blood cell differentiation
The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
lamellocyte cell differentiation
The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
arthropod blood cell proliferation
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
cooperative behavior
social behaviour
A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.
cosuppression
ncRNA-mediated post-transcriptional gene silencing
post-transcriptional gene silencing by RNA
posttranscriptional gene silencing by RNA
PTGS
quelling
RNA interference
RNA-dependent post-transcriptional gene silencing
RNA-mediated post-transcriptional gene silencing
RNA-mediated posttranscriptional gene silencing
RNAi
A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants.
gene silencing by microRNA
gene silencing by miRNA
microRNA-mediated gene silencing
miRNA-mediated gene silencing
A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.
gene silencing by miRNA, production of miRNAs
microRNA biogenesis
microRNA biosynthesis
microRNA biosynthetic process
microRNA metabolic process
microRNA metabolism
microRNA processing
microRNA-mediated gene silencing, production of microRNAs
miRNA biogenesis
miRNA biosynthetic process
miRNA maturation
miRNA-mediated gene silencing, production of miRNAs
production of microRNAs involved in gene silencing by microRNA
production of miRNAs involved in gene silencing by miRNA
Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
microRNA binding
Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
regulation of arthropod blood cell proliferation
The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite.
development of structures derived from the clypeo-labral disc
The series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.
ionotropic glutamate receptor signalling pathway
The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
glutamatergic synaptic transmission
Binding to a G protein-coupled glutamate receptor (a metabotropic glutamate receptor).
G-protein coupled glutamate receptor binding
metabotropic glutamate receptor binding
Binding to a nuclear glucocorticoid receptor.
glucocorticoid receptor binding
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
body growth
The addition of a mannose residue to a protein acceptor molecule.
protein amino acid mannosylation
Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.
procephalic segmentation
Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.
gnathal segmentation
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.
down regulation of dephosphorylation
down-regulation of dephosphorylation
downregulation of dephosphorylation
inhibition of dephosphorylation
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.
activation of dephosphorylation
stimulation of dephosphorylation
up regulation of dephosphorylation
up-regulation of dephosphorylation
upregulation of dephosphorylation
Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.
5\'-3\' exodeoxyribonuclease activity
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.
non-sensory hair organization and biogenesis
trichome organisation
trichome organization and biogenesis
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.
imaginal disc-derived wing hair organization and biogenesis
wing hair organisation
wing hair organization and biogenesis
wing trichome organization and biogenesis
An intercellular bridge that connects the germline cells of a female cyst.
nurse cell ring canal
ovarian ring canal
Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.
TLR binding
An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation.
hippo signal transduction
hippo signaling cascade
hippo signaling pathway
hippo signalling cascade
Salvador-Warts-Hippo signaling pathway
SWH pathway
Any process that modulates the frequency, rate or extent of hippo signaling.
regulation of hippo signaling cascade
regulation of hippo signaling pathway
regulation of hippo signalling cascade
The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
long-chain fatty acyl CoA metabolic process
long-chain fatty acyl-CoA metabolism
The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
fatty acyl CoA metabolic process
fatty-acyl-CoA metabolism
The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
hypoxanthine riboside transport
Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of hypoxanthine riboside transport
The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6-hydroxypurine transport
hypoxanthine transmembrane transport
Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of 6-hydroxypurine transport
The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
coenzyme A membrane transport
The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.
FAD membrane transport
The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
heme membrane transport
The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
NAD membrane transport
A nuclear receptor-mediated signaling pathway initiated by a ligand binding to an intracellular peroxisome proliferator activated receptor (alpha, beta or gamma) of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.
peroxisome proliferator activated receptor signalling pathway
peroxisome proliferator-activated receptor signaling pathway
PPAR signaling pathway
Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
regulation of peroxisome proliferator activated receptor signalling pathway
regulation of peroxisome proliferator-activated receptor signaling pathway
regulation of PPAR signaling pathway
The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5-methyluracil transport
thymine transmembrane transport
Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of 5-methyluracil transport
The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.
growing microtubule plus end
microtubule plus end
A process in which a protein is transported to, or maintained at, a microtubule.
protein localisation to microtubule
The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
sterol influx
sterol uptake
The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
thioester metabolism
The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
thioester anabolism
thioester biosynthesis
thioester formation
thioester synthesis
The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
ROBO signaling pathway
ROBO/SLIT signaling pathway
Roundabout signalling pathway
Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway.
regulation of Roundabout signalling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.
negative regulation of Roundabout signalling pathway
The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CXCL9 production
MIG production
Monokine induced by gamma interferon production
Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.
regulation of CXCL9 production
regulation of MIG production
Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.
provision of T cell help
Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
protein localisation to synapse
Any process that mediates the transfer of information between the extracellular matrix and a cell.
cell-extracellular matrix signalling
extracellular matrix-cell signalling
The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose.
gluconate membrane transport
gluconate transport
Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.
regulation of gluconate membrane transport
regulation of gluconate transport
The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.
acetate membrane transport
The directed movement of copper cation across a membrane.
copper cation transmembrane transport
copper ion membrane transport
The process in which a phosphate is transported across a membrane.
phosphate ion membrane transport
Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.
maintenance of protein localisation in endoplasmic reticulum
maintenance of protein localization in ER
maintenance of protein location in endoplasmic reticulum
maintenance of protein location in ER
protein-endoplasmic reticulum retention
protein-ER retention
retention of protein in endoplasmic reticulum
retention of protein in ER
The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
dipeptide membrane transport
The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds.
tripeptide membrane transport
The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore.
nickel cation membrane transport
The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
borate membrane transport
boron transmembrane transport
The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic to thylakoid membrane
peripheral to thylakoid membrane
The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic to plastid thylakoid membrane
peripheral to plastid thylakoid membrane
The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region.
extrinsic to lumenal leaflet of plastid thylakoid membrane
extrinsic to lumenal side of plastid thylakoid membrane
peripheral to lumenal side of plastid thylakoid membrane
The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic to plastid membrane
peripheral to plastid membrane
The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
extrinsic to plastid inner membrane
peripheral to plastid inner membrane
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.
response to interferon alfa-n1
response to interferon alfa-n3
response to leukocyte interferon
response to lymphoblast interferon
response to lymphoblastoid interferon
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
response to beta-1 interferon
response to fiblaferon
response to fibroblast interferon
response to interferon beta
The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.
cargo loading into vesicle
cargo selection
The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
vitamin membrane transport
The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).
carnosine metabolism
Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
2-oxoglutarate-dependent RNA demethylase
The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore.
proline membrane transport
The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
CCL6 production
Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).
chemokine (C-C motif) ligand 6 secretion
regulation of CCL6 production
regulation of chemokine (C-C motif) ligand 6 secretion
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
intracellular signal transduction pathway
intracellular signaling cascade
intracellular signaling pathway
signal transmission via intracellular cascade
A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via effectors other than beta-catenin.
beta-catenin-independent Wnt receptor signaling pathway
non-canonical Wnt receptor signaling pathway
non-canonical Wnt receptor signalling pathway
non-canonical Wnt-activated signaling pathway
The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.
extracellular sequestering of receptor ligand
negative regulation of protein bioavailability
A G protein-coupled receptor signaling pathway initiated by an extracellular purine or purine derivative binding to its receptor, and ending with the regulation of a downstream cellular process.
G-protein coupled purinergic receptor signaling pathway
G-protein coupled purinergic receptor signalling pathway
The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
P2 receptor signaling pathway
purinergic nucleotide receptor signalling pathway
purinergic receptor signaling pathway
purinergic receptor signalling pathway
purinoceptor signaling pathway
The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.
signaling protein recruiting activity
signaling scaffold activity
signalling adaptor activity
The directed movement of a protein to a specific location within the extracellular region.
establishment of protein localisation in extracellular region
establishment of protein localization in extracellular region
Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.
MTTase
The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.
protein amino acid deacylation
The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.
protein amino acid deglutamylation