NothingMuch/GO-Terms huggingface dataset:
Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + H+.
inositol polyphosphate multikinase activity
inositol trisphosphate 6-kinase activity
IpmK
Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.
1D-myo-inositol-tetrakisphosphate 3-kinase activity
inositol 1,4,5,6-tetrakisphosphate 3-kinase activity
inositol polyphosphate multikinase activity
inositol tetrakisphosphate 3-kinase activity
IpmK
Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.
1D-myo-inositol-tetrakisphosphate 6-kinase activity
inositol 1,3,4,5-tetrakisphosphate 6-kinase activity
inositol tetrakisphosphate 6-kinase activity
Catalysis of the reaction: 1D-myo-inositol hexakisphosphate + ATP = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP.
ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity
Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = ADP + 4,5-bis(diphospho)-1D-myo-inositol (1,2,3,6)tetrakisphosphate.
diphosphoinositol-pentakisphosphate 4-kinase activity
inositol heptakisphosphate 4-kinase activity
IP7 4-kinase activity
Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = ADP + 5,6-bisdiphosphoinositol-1D-myo-inositol (1,2,3,4)tetrakisphosphate.
inositol heptakisphosphate 6-kinase activity
A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.
Ssm4p ubiquitin ligase complex
Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
translation repressor activity, mRNA regulatory element binding
translation repressor activity, nucleic acid binding
The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction.
conidium development
fruiting body formation involved in asexual reproduction
haploid fruiting
homokaryotic fruiting
imperfect stage fruiting body development
monokaryotic fruiting
Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate.
lumazine synthase activity
Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2.
sulfonate/alpha-ketoglutarate dioxygenase activity
sulphonate dioxygenase activity
Catalysis of the reaction: 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + succinate + sulfite.
2-aminoethanesulfonate dioxygenase activity
alpha-ketoglutarate-dependent taurine dioxygenase activity
taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)
The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation.
preprophase band formation
The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles).
phragmoplast formation
The process of marking the site where a division septum will form.
selection of site for barrier cell septum biosynthesis
selection of site for barrier cell septum formation
selection of site for division septum formation
septin assembly and septum biosynthesis
septin assembly and septum formation
septum positioning
A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis.
EMTOC
equatorial microtubule organising centre
A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe.
gamma-tubulin large complex
gamma-tubulin large complex, centrosomal
gamma-tubulin large complex, eMTOC
gamma-tubulin large complex, equatorial microtubule organizing center
gamma-tubulin large complex, equatorial microtubule organizing centre
gamma-tubulin large complex, iMTOC
gamma-tubulin large complex, interphase microtubule organizing center
gamma-tubulin large complex, interphase microtubule organizing centre
gamma-tubulin large complex, mitotic spindle pole body
gamma-tubulin large complex, spindle pole body
gamma-tubulin ring complex, centrosomal
gamma-TuRC
A cell septum that forms following nuclear division.
primary septum
A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles.
Golgi associated retrograde protein complex
VFT tethering complex
Vps fifty three tethering complex
A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog.
Virus-like particle
VLP
The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
branched chain family amino acid catabolic process to alcohol via Ehrlich pathway
The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
branched chain family amino acid catabolic process to carboxylic acid via Ehrlich pathway
The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed.
posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.
MOS4-Associated Complex
nineteen complex
NTC
Prp19/CDC5 complex
A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III.
core RNA polymerase III binding transcription factor activity
RNA polymerase III general initiation factor activity
RNA polymerase III transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding RNA polymerase III transcription factor activity
transcription factor activity, core RNA polymerase III binding
Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.
RNA polymerase III type 1 promoter DNA binding
Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.
RNA polymerase III type 2 promoter DNA binding
Binding to a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
RNA polymerase III type 3 promoter DNA binding
The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions.
sequence-specific DNA binding transcription factor recruiting transcription factor activity
transcription factor activity, sequence-specific DNA binding transcription factor recruiting
transcription factor activity, sequence-specific DNA-binding transcription factor recruiting
The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter.
snoRNA transcription from a type 2 RNA polymerase III promoter
The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
snoRNA transcription from an RNA polymerase II promoter
Binding to a DNA region that controls the transcription of the mitochondrial DNA.
HSP coding strand binding
HSP non-coding strand binding
HSPas binding
HSPs binding
LSP coding strand binding
LSP non-coding strand binding
LSPas binding
LSPs binding
mitochondrial heavy strand promoter anti-sense binding
mitochondrial heavy strand promoter sense binding
mitochondrial light strand promoter anti-sense binding
mitochondrial light strand promoter sense binding
mitochondrial proximal promoter sequence-specific DNA binding
mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding
mitochondrial RNA polymerase core promoter sequence-specific DNA binding
mitochondrial RNA polymerase regulatory region DNA binding
mitochondrial RNA polymerase regulatory region sequence-specific DNA binding
Binding to a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.
RNA polymerase III hybrid type promoter DNA binding
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
DNA-directed RNA polymerase activity involved in transcription from RNA polymerase I promoter
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
DNA-directed RNA polymerase activity involved in transcription from RNA polymerase IV promoter
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
DNA-directed RNA polymerase activity involved in transcription from RNA polymerase V promoter
The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter.
transcription from RNA pol IV promoter
transcription from RNA polymerase IV promoter
A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.
RNA binding transcription factor activity
RNA binding transcription regulator activity
Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein.
RNA binding transcription antitermination factor activity
Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein.
DNA binding transcription antitermination factor activity
A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
positive regulation of transcription from RNA polymerase II promoter by nitrogen catabolites
A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
negative regulation of transcription from RNA polymerase II promoter by nitrogen catabolites
Binding to a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
TFIIA-class transcription factor binding
Binding to a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIID-class transcription factor binding
Binding to a general RNA polymerase II transcription factor belonging to the TFIIE complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIIE-class transcription factor binding
Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIIF-class transcription factor binding
Binding to a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
TFIIH-class transcription factor binding
Binding to a component of the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase.
basal bacterial-type RNA polymerase transcription machinery binding
A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase.
promoter clearance from RNA polymerase III promoter
The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components.
transcription protein-DNA-RNA complex disassembly
Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
core RNA polymerase II recruiting transcription factor activity
transcription factor activity, core RNA polymerase II recruiting
Binding to a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.
bacterial-type RNA polymerase termination site sequence-specific DNA binding
mitochondrial RNA polymerase termination site sequence-specific DNA binding
mitochondrial RNA polymerase terminator site sequence-specific DNA binding transcription factor activity
transcription factor activity, mitochondrial RNA polymerase terminator site sequence-specific binding
transcription termination site DNA binding
Binding to a general RNA polymerase III transcription factor belonging to the TFIIB complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.
TFIIIB-class transcription factor binding
Binding to a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.
TFIIIC-class transcription factor binding
Binding to a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE.
RNA polymerase I CORE element sequence-specific DNA binding
RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity
transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting
Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase I. RNA polymerase I elements are referred to either enhancers or upstream control element (UCE, or alternately referred to as the upstream element).
RNA polymerase I enhancer sequence-specific DNA binding
RNA polymerase I upstream control element sequence-specific DNA binding
RNA polymerase I upstream element sequence-specific DNA binding
Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
regulation of transcriptional open complex formation at RNA polymerase II promoter
Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
regulation of transcription start site selection at RNA polymerase II promoter
Binding to an RNA polymerase I transcription factor, a protein required to initiate or regulate transcription by RNA polymerase I.
RNA polymerase I transcription factor binding
A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs.
core RNA polymerase I binding transcription factor activity
general RNA polymerase I transcription factor activity
RNA polymerase I transcription general initiation factor activity
transcription factor activity, core RNA polymerase I binding
A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.
promoter clearance from RNA polymerase I promoter
promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript
RNA polymerase I promoter escape