NothingMuch/GO-Terms huggingface dataset:
Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate.
all-trans-heptaprenyl-diphosphate synthase activity
HepPP synthase activity
heptaprenyl pyrophosphate synthase activity
heptaprenyl pyrophosphate synthetase activity
trans-hexaprenyltranstransferase activity
A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
enolase complex
Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.
lactose galactohydrolase activity
The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).
malt sugar biosynthesis
malt sugar biosynthetic process
maltose anabolism
maltose biosynthesis
maltose formation
maltose synthesis
The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).
malt sugar catabolic process
malt sugar catabolism
maltose breakdown
maltose degradation
maltose hydrolysis
The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.
cell wall mannoprotein anabolism
cell wall mannoprotein biosynthesis
cell wall mannoprotein formation
cell wall mannoprotein synthesis
Catalysis of the reaction: adenine + H+ + H2O = hypoxanthine + NH4+.
ADase activity
adenase activity
adenine aminase activity
adenine aminohydrolase activity
Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
acyl-CoA or acyl binding
Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.
ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process
The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.
ornithine cycle
urea biosynthesis
urea biosynthetic process
The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate.
argininosuccinate metabolism
The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.
G1 phase of mitotic cell cycle
The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.
S phase of mitotic cell cycle
S-phase of mitotic cell cycle
The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.
G2 phase of mitotic cell cycle
Enables the transfer of S-methylmethionine from one side of a membrane to the other.
S-methylmethionine permease activity
S-methylmethionine transporter activity
Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
L-methionine porter activity
Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H+.
glutamine amidotransferase:cyclase activity
imidazole glycerol phosphate synthase activity
imidazole-glycerol-phosphate synthase activity
imidazoleglycerol phosphate synthase activity
One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively.
NEF1 complex
XPA-ERCC1-ERCC4 complex
One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p.
NEF2 complex
One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p.
NEF4 complex
Catalysis of the reaction: H2O + sn-glycerol 1-phosphate = glycerol + phosphate.
alpha-glycerol phosphatase activity
alpha-glycerophosphatase activity
glycerol 3-phosphatase activity
glycerol 3-phosphate phosphohydrolase activity
glycerol-1-phosphate phosphohydrolase activity
glycerol-3-phosphate phosphatase activity
A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).
PCAF complex
PCAF histone acetylase-associated complex
Spt-Ada-Gcn5-acetyltransferase complex
SPT3-TAF9-GCN5 acetylase complex
SPT3-TAF9-PCAF acetylase complex
STAGA coactivator complex
STAGA complex
Catalysis of the reaction: 1-hexadecanoyl-sn-glycero-3-phosphate + NADP+ = 1-hexadecanoylglycerone 3-phosphate + H+ + NADPH.
1-acyldihydroxyacetone-phosphate reductase activity
1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity
acyldihydroxyacetone phosphate reductase activity
palmitoyl dihydroxyacetone phosphate reductase activity
palmitoyl-dihydroxyacetone-phosphate reductase activity
palmitoyldihydroxyacetone-phosphate reductase activity
A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae.
neck ring
A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.
exocyst complex
Sec6/8 complex
A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.
(1->3)-beta-glucan synthase complex
1,3-beta-glucan synthase complex
Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
RecA-family recombinase activity
recombinase activity
strand exchange activity
strand transferase
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
two-component sensor activity
two-component sensor molecule
two-component system sensor activity
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
two-component response regulator activity
A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
PP2A complex
PP2A-pi
PP2a-protector
protein phosphatase 2 complex
The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
aromatic amino acid family biosynthetic process, anthranilate pathway
tryptophan anabolism
tryptophan biosynthesis
tryptophan formation
tryptophan synthesis
Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA.
RNase MRP
A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
ribonuclease mitochondrial RNA processing complex
RNase MRP complex
Catalysis of the reaction: NAD+ + H2O = AMP + NMN.
NAD diphosphatase activity
NAD pyrophosphatase activity
NAD(+) pyrophosphatase activity
NAD+ phosphohydrolase activity
NAD+ pyrophosphatase activity
NADP pyrophosphatase activity
nicotinamide adenine dinucleotide pyrophosphatase activity
Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
tRNA splicing endonuclease activity
tRNA-intron endoribonuclease activity
A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
SEN complex
tRNA splicing endonuclease complex
Catalysis of the reaction: 2'-phospho- + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.
2\'-phospho-:NAD+ phosphotransferase activity
2\'-phospho-tRNA:NAD+ phosphotransferase activity
2\'-phosphotransferase activity
Tpt1
Tpt1p
yeast 2\'-phosphotransferase activity
The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.
plasma membrane hydrogen ion-transporting ATPase V0 domain
The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane.
plasma membrane hydrogen ion-transporting ATPase V1 domain
Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.
glycopeptidase activity
glycopeptide N-glycosidase activity
jack-bean glycopeptidase
N-glycanase activity
N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity
N-oligosaccharide glycopeptidase activity
peptide:N-glycanase
PNGase
PNGase A
PNGase F
Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.
6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity
acetylglucosaminylphosphatidylinositol deacetylase activity
GlcNAc-PI de-N-acetylase activity
GlcNAc-PI deacetylase activity
N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity
N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity
Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate.
phosphoethanolamine methyltransferase activity
S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity
A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.
mammalian spliceosomal complex E
mammalian spliceosomal E complex
yeast spliceosomal complex CC
The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.
assembly of spliceosomal tri-snRNP
assembly of spliceosomal tri-snRNP U4/U6.U5
assembly of spliceosomal tri-snRNP U4atac/U6atac.U5
snRNP recycling
spliceosomal tri-snRNP assembly
spliceosomal tri-snRNP U4/U6.U5 assembly
spliceosomal tri-snRNP U4atac/U6atac.U5 assembly
Catalysis of the reaction: ergosterol + NADP+ = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H+ + NADPH.
C-24(28) sterol reductase activity
D24(24-1)-sterol reductase activity
delta24(241)-sterol reductase activity
ergosterol:NADP+ delta24(241)-oxidoreductase activity
sterol Delta(24(28))-methylene reductase activity
sterol Delta(24(28))-reductase activity
sterol delta-24(28) methylene reductase activity
sterol delta-24(28) reductase activity
sterol delta24(28)-methylene reductase activity
sterol delta24(28)-reductase activity
Catalysis of the reaction: fecosterol = episterol.
delta-8-delta-7 sterol isomerase activity
Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.
sterol-C5-desaturase activity
Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.
(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)
2,3-epoxysqualene lanosterol cyclase activity
2,3-epoxysqualene--lanosterol cyclase activity
2,3-epoxysqualene-lanosterol cyclase activity
2,3-oxidosqualene sterol cyclase activity
2,3-oxidosqualene-lanosterol cyclase activity
lanosterol 2,3-oxidosqualene cyclase activity
OSC
oxidosqualene--lanosterol cyclase activity
oxidosqualene-lanosterol cyclase activity
oxidosqualene:lanosterol cyclase activity
squalene 2,3-epoxide:lanosterol cyclase activity
squalene epoxidase-cyclase activity
squalene-2,3-oxide-lanosterol cyclase activity
Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.
3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)
3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)
3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)
3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity
C-3 sterol dehydrogenase (C-4 decarboxylase) activity
C-3 sterol dehydrogenase activity
sterol 4alpha-carboxylic decarboxylase activity
sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H+.
3-keto-steroid reductase activity
3-KSR activity
3beta-hydroxy-steroid:NADP+ 3-oxidoreductase
Catalysis of the reaction: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)- + 5 H+ + 3 O2 = 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + 6 Fe(III)- + 4 H2O.
4-methylsterol oxidase activity
methylsterol hydroxylase activity
methylsterol monooxygenase activity
A chromosome found in the mitochondrion of a eukaryotic cell.
mitochondrial DNA
mitochondrial genome
mtDNA
Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c.
cytochrome c (lysine) methyltransferase activity
cytochrome c methyltransferase activity
cytochrome c-lysine N-methyltransferase activity
cytochrome c-specific protein methylase III activity
cytochrome c-specific protein-lysine methyltransferase activity
S-adenosyl-L-methionine:cytochrome c-L-lysine 6-N-methyltransferase activity
S-adenosyl-L-methionine:cytochrome c-L-lysine N6-methyltransferase activity
Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + H+.
ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity
phosphatidylinositol 3-phosphate 5-kinase activity
phosphatidylinositol-3-phosphate 5-kinase activity
type III PIP kinase activity
Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+.
AlaDH
alanine oxidoreductase activity
alpha-alanine dehydrogenase activity
L-alanine dehydrogenase activity
L-alanine:NAD+ oxidoreductase (deaminating)
NAD-dependent alanine dehydrogenase activity
NAD-linked alanine dehydrogenase activity
NADH-dependent alanine dehydrogenase activity
Binding to a magnesium (Mg) ion.
magnesium binding
Mg binding
The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.
group I intron catabolic process
RNA fragment breakdown
RNA fragment catabolism
RNA fragment degradation
A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends.
nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay
nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay
Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues.
metaphosphatase activity
polymetaphosphatase activity
polyphosphatase activity
polyphosphate depolymerase activity
polyphosphate polyphosphohydrolase activity
Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm.
CDK holoenzyme
Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+.
adenosine triphosphate-nicotinamide mononucleotide transadenylase activity
ATP:nicotinamide-nucleotide adenylyltransferase activity
ATP:NMN adenylyltransferase activity
diphosphopyridine nucleotide pyrophosphorylase activity
NAD(+) diphosphorylase activity
NAD(+) pyrophosphorylase activity
NAD+ diphosphorylase activity
NAD+ pyrophosphorylase activity
nicotinamide adenine dinucleotide pyrophosphorylase activity
nicotinamide mononucleotide adenylyltransferase activity
NMN adenylyltransferase activity
NMNAT activity
Catalysis of the reaction: diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine.
5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase activity
Xan phosphoribosyltransferase activity
xanthine-guanine phosphoribosyltransferase activity
xanthosine 5\'-phosphate pyrophosphorylase activity
xanthylate pyrophosphorylase activity
xanthylic pyrophosphorylase activity
XMP pyrophosphorylase activity
XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase activity
Enables the transfer of sulfite ions from one side of a membrane to the other.
sulphite transporter activity
The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae.
lumen of vacuole with cell cycle-correlated morphology
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
fungal-type vacuolar membrane
membrane of vacuole with cell cycle-correlated morphology
Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA.
telomerase RNA
telomerase, template
The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition.
TERT-TERC complex
Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.
3-hydroxyanthranilate oxygenase activity
3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
3-hydroxyanthranilic acid dioxygenase activity
3-hydroxyanthranilic acid oxygenase activity
3-hydroxyanthranilic oxygenase activity
3HAO
Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.
RNA m7G cap binding
Binding to the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.
RNA m2,2,7G cap binding
A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex.
PEP-A
A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation.
PEP-B
Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.
nuclear mRNA branch site recognition
spliceosomal A complex biosynthesis
spliceosomal A complex formation
spliceosomal B complex biosynthesis
spliceosomal B complex formation
U12-type nuclear mRNA branch site recognition
U2-type nuclear mRNA branch site recognition
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.
catalytic spliceosome assembly for first transesterification step
formation of catalytic spliceosome for first transesterification step
spliceosomal A2-2 complex biosynthesis
spliceosomal A2-2 complex formation
spliceosomal C1 complex biosynthesis
spliceosomal C1 complex formation
U12-type catalytic spliceosome formation for first transesterification step
U2-type catalytic spliceosome formation for first transesterification step