NothingMuch/GO-Terms huggingface dataset:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
FGF receptor signaling pathway involved in negative regulation of apoptosis in bone marrow
FGFR signaling pathway involved in negative regulation of apoptosis in bone marrow
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptosis in bone marrow
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow
fibroblast growth factor receptor signalling pathway involved in negative regulation of apoptotic process in bone marrow
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.
FGF receptor signaling pathway involved in hematopoiesis
FGFR signaling pathway involved in hematopoiesis
fibroblast growth factor receptor signaling pathway involved in hematopoiesis
fibroblast growth factor receptor signalling pathway involved in hemopoiesis
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
FGF receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
FGFR signaling pathway involved in positive regulation of cell proliferation in bone marrow
fibroblast growth factor receptor signalling pathway involved in positive regulation of cell proliferation in bone marrow
Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.
protein nitrosylase activity
S-nitrosylase activity
Transfer of a nitric oxide (NO) group from one cysteine residue to another.
cysteine to cysteine nitrosylation
cysteine-to-cysteine transnitrosylation
protein-to-protein transnitrosylation
S-transnitrosylation
The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.
FGF receptor signaling pathway involved in orbitofrontal cortex development
FGFR signaling pathway involved in orbitofrontal cortex development
fibroblast growth factor receptor signalling pathway involved in orbitofrontal cortex development
The removal of a C-terminal, gene-encoded glutamate residue from a protein.
protein primary sequence deglutamylation
The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.
removal of posttranslational polyglutamylation
shortening of glutamate side chain
Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
AP-2 clathrin adaptor complex binding
Binding to a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
small nuclear RNA stem-loop binding
snRNA hairpin binding
snRNA hairpin loop binding
Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles.
clathrin-associated adaptor activity
The disaggregation of a stress granule into its constituent protein and RNA parts.
SG disassembly
The tip portion of an outgrowth of a root epidermal cell.
root hair cell tip
The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.
endoplasmic reticulum to Golgi ceramide transport
ER to Golgi ceramide translocation
non-vesicular ceramide trafficking
The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).
IHBD development
intrahepatic biliary duct development
A renal system process in which D-glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
glucose reabsorption
nephron glucose absorption
renal glucose absorption
The series of molecular signals initiated by a juvenile hormone binding to its receptor, a bHLH-PAS transcription factor, to regulate gene expression.
juvenile hormone mediated signalling pathway
juvenile hormone-mediated signaling pathway
A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.
mitochondrial inner membrane prohibitin complex
Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to the arginine residue at position 17 of histone H3.
histone methylase activity (H3-R17 specific)
histone methyltransferase activity (H3-R17 specific)
histone-arginine N-methyltransferase activity (H3-R17 specific)
histone-H3R17 methyltransferase activity
Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine.
L-beta-(3,4-Dihydroxyphenyl)alanine receptor activity
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.
intestinal smooth muscle cell differentiation
The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.
circadian mating behaviour
circadian mating rhythm
Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking.
cargo loading into clathrin-coated vesicle, AP-1-mediated
Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle.
cargo loading into clathrin-coated vesicle, AP-3-mediated
A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.
eRF1 MTase complex
The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
MyD88-dependent TLR4 signaling pathway
MyD88-dependent toll-like receptor 4 signalling pathway
The series of molecular signals initiated by a ligand binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.
MyD88-dependent TLR2 signaling pathway
MyD88-dependent toll-like receptor 2 signalling pathway
Binding to a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
TLR4 binding
Binding to a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.
TLR2 binding
The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
MAL-dependent toll-like receptor 4 signaling pathway
MyD88 adapter-like dependent toll-like receptor 4 signaling pathway
TIRAP-dependent TLR4 signaling pathway
TIRAP-dependent toll-like receptor 4 signalling pathway
The series of molecular signals initiated by a ligand binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR4 signaling pathway
TRIF-dependent TLR4 signaling pathway
TRIF-dependent toll-like receptor 4 signalling pathway
The series of molecular signals initiated by a ligand binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
TRAM-dependent TLR4 signaling pathway
TRAM-dependent toll-like receptor 4 signalling pathway
The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.
memory T-cell extravasation
A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.
flagellar fibrous sheath
flagellum fibrous sheath
The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
Th1 cell diapedesis
The series of molecular signals initiated by chemokine CCL5 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
CCL5-mediated signaling pathway
chemokine (C-C motif) ligand 5 signalling pathway
RANTES-mediated signaling pathway
The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.
catabolism of mitochondrial protein
degradation of damaged mitochondrial protein
The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
MIV-mediated mitophagy
The movement of a monocyte from the bone marrow to the blood stream.
release of monocytes into circulation
The directed movement of a helper T cell in response to an external stimulus.
T-helper cell chemotaxis
The directed movement of a T-helper 17 cell in response to an external stimulus.
Th17 cell chemotaxis
The directed movement of a T-helper 1 cell in response to an external stimulus.
Th1 cell chemotaxis
The directed movement of a T-helper 2 cell in response to an external stimulus.
Th2 cell chemotaxis
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.
cellular response to NO2
Binding to chemokine (C-C motif) ligand 2.
CCL2 binding
Binding to chemokine (C-C motif) ligand 12.
CCL12 binding
Binding to chemokine (C-C motif) ligand 7.
CCL7 binding
Binding to the cytokine, macrophage migration inhibitory factor.
MIF binding
The directed movement of tRNA from the cytoplasm to the nucleus.
retrograde tRNA transport into nucleus
tRNA nuclear import
The series of molecular signals initiated by interleukin-12 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
IL-12-mediated signaling pathway
interleukin-12-mediated signalling pathway
The series of molecular signals initiated by interleukin-15 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
IL-15-mediated signaling pathway
interleukin-15-mediated signalling pathway
Binding to lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors.
LPA binding
Binding to S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.
GSNO binding
Binding to a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO.
dinitrosyl-diglutathionyl-iron complex binding
DNDGIC binding
DNIC binding
The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.
NO storage
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
intraciliary transport involved in cilium morphogenesis
intraflagellar transport
intraflagellar transport involved in cilium morphogenesis
Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.
protein localisation to myelin sheath abaxonal region
Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
lysosome pH elevation
Binding to chemokine (C-C motif) ligand 19.
CCL19 binding
Binding to chemokine (C-C motif) ligand 21.
CCL21 binding
The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.
cytoplasmic poly(A)-dependent rRNA catabolic process
The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.
dorsal motor nucleus of vagus nerve structural organisation
The movement of a B cell to cross a high endothelial venule in response to an external stimulus.
B-cell chemotaxis across high endothelial venule
The series of molecular signals initiated by interleukin-13 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
IL-13-mediated signaling pathway
interleukin-13-mediated signalling pathway
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
positive regulation of insulin secretion in response to glucose
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).
angioblastic mesenchymal cell differentiation
The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.
activated natural killer cell chemotaxis
A homeostatic process involved in the maintenance of a steady state level of nickel ions within a cell.
cellular nickel homeostasis
cellular nickel ion homeostasis
A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.
other organism post-synaptic membrane
other organism postsynaptic membrane
Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration resulting from the platelet-derived growth factor receptor-beta signaling pathway.
positive regulation of metanephric mesenchymal cell migration by betaPDGF receptor signaling pathway
positive regulation of metanephric mesenchymal cell migration by PDGF receptor-beta signaling pathway
positive regulation of metanephric mesenchymal cell migration by PDGFR-beta signaling pathway
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway
A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
ATP-binding cassette (ABC) transporter complex, ECF-type
energy coupling factor (ECF)-type ABC transporter
energy-coupling factor transporter
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite . Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride).
S-adenosyl-L-methionine-dependent tellurite methyltransferase activity
SAM-dependent tellurite methyltransferase activity
tellurite methylase activity
Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+.
NADPH:2-alkenal alpha,beta-hydrogenase activity
The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).
adrenal gland cortex formation
The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
structural constituent of vitelline envelope
structural constituent of zona pellucida
An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis.
diuresis resulting from pressure natriuresis
An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.
natriuresis resulting from pressure natriuresis
The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants.
palmatine anabolism
palmatine biosynthesis
palmatine formation
palmatine synthesis
The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid.
berbamunine anabolism
berbamunine biosynthesis
berbamunine formation
berbamunine synthesis
A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth.
new cell tip after activation of bipolar cell growth
post-NETO new cell end
post-NETO new cell tip
post-new end take-off new cell tip
A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.
post-NETO old cell end
post-NETO old cell tip
post-new end take-off old cell tip
A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.
photoreceptor cell outer segment organisation
photoreceptor outer segment organization
The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
uterus epithelial development
The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.
fallopian tube morphogenesis
Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors.
KRAB domain binding
Krueppel-associated box binding
A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
chromosomal passenger complex localization to spindle midzone
chromosome passenger complex localisation to spindle midzone
chromosome passenger complex localization to central spindle
chromosome passenger complex localization to spindle equator
CPC complex localization to spindle midzone
CPC localization to spindle midzone