Extraction schema:
{"type": "object", "title": "Real-content CSR subject disposition listing extraction schema", "description": "Extract listing metadata and every subject disposition row from a clinical study report appendix listing. One row per subject under a repeated two-line column header; blank cells mean not applicable.", "required": ["cro_study_number", "sponsor_protocol_number", "listing_number", "listing_title", "study_population", "footnote", "dispositions"], "properties": {"cro_study_number": {"type": "string", "description": "CRO study number from the page header, e.g. '7694-105'."}, "sponsor_protocol_number": {"type": "string", "description": "Sponsor protocol number from the page header, e.g. 'SM 08-01'."}, "listing_number": {"type": "string", "description": "Listing number from the title line, e.g. '16.2.1-1'."}, "listing_title": {"type": "string", "description": "Listing title text, e.g. 'Subject Dispositions'."}, "study_population": {"type": "string", "description": "Population named on the 'Study Population:' line."}, "footnote": {"type": "string", "description": "Superscript-a footnote text at the bottom of each page."}, "dispositions": {"type": "array", "description": "Every subject row in document order.", "items": {"type": "object", "required": ["subject_number", "status", "date", "study_day", "reason_if_withdrawn", "specify", "investigator_comments", "source_page"], "properties": {"subject_number": {"type": "string", "description": "Subject identifier, first column, e.g. 'R1001'."}, "status": {"type": "string", "enum": ["Completed", "Withdrawn"], "description": "Completed/Withdrawn column as printed."}, "date": {"type": "string", "description": "Disposition date as printed (YYYY-MM-DD)."}, "study_day": {"type": "integer", "description": "Study Day column (footnote a: relative to Day 1)."}, "reason_if_withdrawn": {"type": ["string", "null"], "description": "Withdrawal reason category; also printed for some Completed subjects (e.g. 'Other'). Null when blank."}, "specify": {"type": ["string", "null"], "description": "Free-text specification of the reason; null when blank."}, "investigator_comments": {"type": ["string", "null"], "description": "Investigator Comments column; null when blank."}, "source_page": {"type": "integer", "description": "1-indexed PDF page of the row."}}}}}}

Expected output:
{"cro_study_number": "7694-105", "sponsor_protocol_number": "SM 08-01", "listing_number": "16.2.1-1", "listing_title": "Subject Dispositions", "study_population": "ITT", "footnote": "Study Day is relative to the date of first study product administration (Day 1).", "dispositions": [{"subject_number": "R1001", "status": "Completed", "date": "2009-09-11", "study_day": 194, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1002", "status": "Completed", "date": "2009-09-16", "study_day": 199, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1003", "status": "Withdrawn", "date": "2009-03-09", "study_day": 7, "reason_if_withdrawn": "Adverse Event", "specify": "Sore Gums", "investigator_comments": null, "source_page": 3}, {"subject_number": "R1004", "status": "Completed", "date": "2009-09-21", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1005", "status": "Completed", "date": "2009-09-22", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1006", "status": "Completed", "date": "2009-09-23", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1007", "status": "Completed", "date": "2009-09-23", "study_day": 195, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1008", "status": "Withdrawn", "date": "2009-05-28", "study_day": 74, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1009", "status": "Withdrawn", "date": "2009-06-01", "study_day": 78, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1010", "status": "Completed", "date": "2009-10-06", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1011", "status": "Completed", "date": "2009-10-29", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 3}, {"subject_number": "R1012", "status": "Completed", "date": "2009-10-29", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1013", "status": "Completed", "date": "2009-11-04", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1014", "status": "Withdrawn", "date": "2009-05-20", "study_day": 29, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1015", "status": "Completed", "date": "2009-11-10", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1016", "status": "Completed", "date": "2009-11-24", "study_day": 194, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1017", "status": "Completed", "date": "2009-11-20", "study_day": 190, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1018", "status": "Withdrawn", "date": "2009-07-24", "study_day": 71, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1019", "status": "Completed", "date": "2009-12-04", "study_day": 198, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1020", "status": "Withdrawn", "date": "2009-11-23", "study_day": 173, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1021", "status": "Completed", "date": "2009-12-17", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 4}, {"subject_number": "R1022", "status": "Completed", "date": "2009-12-30", "study_day": 205, "reason_if_withdrawn": "Other", "specify": "Subject Completed Study But Was Out Of Window", "investigator_comments": null, "source_page": 4}, {"subject_number": "R1023", "status": "Withdrawn", "date": "2009-07-30", "study_day": 43, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1024", "status": "Completed", "date": "2010-01-06", "study_day": 198, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1025", "status": "Completed", "date": "2010-01-07", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1026", "status": "Completed", "date": "2010-01-07", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1027", "status": "Withdrawn", "date": "2009-07-28", "study_day": 27, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1028", "status": "Completed", "date": "2010-01-29", "study_day": 212, "reason_if_withdrawn": "Other", "specify": "Subject Completed But Was Out Of Window", "investigator_comments": null, "source_page": 5}, {"subject_number": "R1029", "status": "Withdrawn", "date": "2009-09-21", "study_day": 78, "reason_if_withdrawn": "Adverse Event", "specify": "Vaginal Bleeding With Pregnancy", "investigator_comments": null, "source_page": 5}, {"subject_number": "R1030", "status": "Completed", "date": "2010-01-28", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1031", "status": "Completed", "date": "2010-01-28", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1032", "status": "Withdrawn", "date": "2009-11-06", "study_day": 113, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1033", "status": "Withdrawn", "date": "2009-09-04", "study_day": 46, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 5}, {"subject_number": "R1034", "status": "Completed", "date": "2010-02-11", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R1035", "status": "Completed", "date": "2010-02-11", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R1036", "status": "Withdrawn", "date": "2009-11-03", "study_day": 97, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R1037", "status": "Completed", "date": "2010-02-12", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R2001", "status": "Withdrawn", "date": "2009-05-18", "study_day": 67, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R2002", "status": "Completed", "date": "2009-09-29", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R2003", "status": "Completed", "date": "2009-10-01", "study_day": 198, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R2004", "status": "Withdrawn", "date": "2009-05-14", "study_day": 53, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R2005", "status": "Completed", "date": "2009-10-06", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R2006", "status": "Withdrawn", "date": "2009-08-04", "study_day": 132, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R2007", "status": "Completed", "date": "2009-10-29", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 6}, {"subject_number": "R2008", "status": "Withdrawn", "date": "2009-06-18", "study_day": 60, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2009", "status": "Completed", "date": "2009-11-03", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2010", "status": "Completed", "date": "2009-11-04", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2011", "status": "Completed", "date": "2009-11-05", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2012", "status": "Completed", "date": "2009-11-09", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2013", "status": "Completed", "date": "2009-11-10", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2014", "status": "Completed", "date": "2009-11-16", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2015", "status": "Completed", "date": "2009-11-17", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2016", "status": "Completed", "date": "2009-11-20", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2017", "status": "Completed", "date": "2009-11-20", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2018", "status": "Withdrawn", "date": "2009-07-07", "study_day": 47, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 7}, {"subject_number": "R2019", "status": "Completed", "date": "2009-12-08", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2020", "status": "Withdrawn", "date": "2009-07-24", "study_day": 59, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2021", "status": "Completed", "date": "2009-12-11", "study_day": 190, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2022", "status": "Completed", "date": "2010-02-11", "study_day": 228, "reason_if_withdrawn": "Other", "specify": "Subject Completed, But Was Out Of Window", "investigator_comments": null, "source_page": 8}, {"subject_number": "R2023", "status": "Withdrawn", "date": "2009-12-22", "study_day": 174, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2024", "status": "Completed", "date": "2010-01-29", "study_day": 205, "reason_if_withdrawn": "Other", "specify": "Subject Completed, But Was Out Of Window", "investigator_comments": null, "source_page": 8}, {"subject_number": "R2025", "status": "Withdrawn", "date": "2009-10-13", "study_day": 93, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2026", "status": "Completed", "date": "2010-01-27", "study_day": 198, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2027", "status": "Completed", "date": "2010-01-27", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2028", "status": "Completed", "date": "2010-02-03", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2029", "status": "Completed", "date": "2010-02-04", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 8}, {"subject_number": "R2030", "status": "Withdrawn", "date": "2009-09-09", "study_day": 43, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R2031", "status": "Completed", "date": "2010-02-11", "study_day": 196, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R2032", "status": "Withdrawn", "date": "2009-10-14", "study_day": 71, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3001", "status": "Completed", "date": "2009-09-14", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3002", "status": "Completed", "date": "2009-09-14", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3003", "status": "Completed", "date": "2009-09-15", "study_day": 198, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3004", "status": "Completed", "date": "2009-09-14", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3005", "status": "Withdrawn", "date": "2009-06-11", "study_day": 101, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3006", "status": "Completed", "date": "2009-09-16", "study_day": 198, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3007", "status": "Completed", "date": "2009-09-16", "study_day": 198, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3008", "status": "Completed", "date": "2009-09-15", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 9}, {"subject_number": "R3009", "status": "Withdrawn", "date": "2009-05-06", "study_day": 58, "reason_if_withdrawn": "Adverse Event", "specify": "Glossitis And Pharyngitis", "investigator_comments": null, "source_page": 10}, {"subject_number": "R3010", "status": "Completed", "date": "2009-09-22", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3011", "status": "Completed", "date": "2009-10-05", "study_day": 195, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3012", "status": "Withdrawn", "date": "2009-04-22", "study_day": 24, "reason_if_withdrawn": "Adverse Event", "specify": "Acne Vulgaris, Diarrhea, Dyspepsia", "investigator_comments": null, "source_page": 10}, {"subject_number": "R3013", "status": "Completed", "date": "2009-10-19", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3014", "status": "Withdrawn", "date": "2009-07-17", "study_day": 102, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3015", "status": "Withdrawn", "date": "2009-06-04", "study_day": 59, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3016", "status": "Completed", "date": "2009-10-27", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3017", "status": "Withdrawn", "date": "2009-05-26", "study_day": 42, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3018", "status": "Withdrawn", "date": "2009-09-29", "study_day": 168, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3019", "status": "Completed", "date": "2009-11-10", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 10}, {"subject_number": "R3020", "status": "Completed", "date": "2009-11-10", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3021", "status": "Withdrawn", "date": "2009-06-29", "study_day": 56, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3022", "status": "Completed", "date": "2009-11-16", "study_day": 196, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3023", "status": "Withdrawn", "date": "2009-06-17", "study_day": 44, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3024", "status": "Withdrawn", "date": "2009-06-08", "study_day": 28, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3025", "status": "Withdrawn", "date": "2009-08-04", "study_day": 85, "reason_if_withdrawn": "Adverse Event", "specify": "Dysesthesia", "investigator_comments": null, "source_page": 11}, {"subject_number": "R3026", "status": "Completed", "date": "2009-11-18", "study_day": 190, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3027", "status": "Withdrawn", "date": "2009-07-27", "study_day": 76, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3028", "status": "Completed", "date": "2009-11-23", "study_day": 189, "reason_if_withdrawn": "Other", "specify": "Subject Completed But Was Out Of Window", "investigator_comments": null, "source_page": 11}, {"subject_number": "R3029", "status": "Withdrawn", "date": "2009-07-23", "study_day": 66, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3030", "status": "Withdrawn", "date": "2009-06-09", "study_day": 22, "reason_if_withdrawn": "Lost To Follow-Up", "specify": null, "investigator_comments": null, "source_page": 11}, {"subject_number": "R3031", "status": "Completed", "date": "2009-11-24", "study_day": 190, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 12}, {"subject_number": "R3032", "status": "Withdrawn", "date": "2009-06-16", "study_day": 28, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 12}, {"subject_number": "R4001", "status": "Withdrawn", "date": "2009-06-22", "study_day": 113, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 12}, {"subject_number": "R4002", "status": "Completed", "date": "2009-09-14", "study_day": 197, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 12}, {"subject_number": "R4003", "status": "Completed", "date": "2009-09-15", "study_day": 198, "reason_if_withdrawn": null, "specify": null, "investigator_comments": null, "source_page": 12}, {"subject_number": "R4004", "status": "Withdrawn", "date": "2009-04-14", "study_day": 44, "reason_if_withdrawn": "Consent Withdrawn", "specify": null, "investigator_comments": null, "source_page": 12}, {"subject_number": "R4005", "status": "Completed", "date": "2009-09-15", 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