Skyrim:Radiant

Skyrim uses a Radiant system for dynamically generating game content. This helps to make each playthrough unique, but it is also designed to try and get you to visit each location at least once.
 
Quests
The Radiant quest system is a quest generator that creates quests from a series of components such as location, enemy type, and reward. Some of these components are randomized, but not all.  The randomized components are generated every time that the quest is triggered. Radiant quests are used throughout the game in various faction questlines and in miscellaneous quests.

This quest system cannot create large, complicated, or particularly interesting quests, but it can create a near infinite number of quests with a fraction of the time and effort required to create a traditional one. It works with a system that aims to send you to a location that you have not yet discovered, and it also works to keep you engaged with fresh and interesting discoveries.

Quest Locations
 
Most radiant quests have a set of about a dozen possible locations where you may be sent to complete the quest.  Typically, those locations are selected based on the location's occupants and/or hold.  For example, a quest might take place in any Hagraven nest, or any Bandit camp in Falkreath Hold.  In these cases, the quest page contains a list of all possible locations, and that quest is listed as a related quest on the page describing each of those locations.

However, some radiant quests have a much longer list of possible locations.  All such quests are listed here, but these quests are not listed on each possible location page.

Dungeons
 
Any bandit camp or dwarven ruin
 
Any dungeon that contains a boss chest (140+ possible dungeons)
 
Many dungeons that have a bandit leader (25+ possible locations)
 
Most dungeons that have a boss chest (75+ possible dungeons)
 
Any dungeon that contains a boss chest (140+ possible dungeons)
 
Most dungeons that have a boss chest (65+ possible dungeons)
 
Any bandit camp or warlock lair
 
Most dungeons that have a boss enemy and a place to lock up a captive (50+ possible dungeons)
 
Any dungeon that contains a boss chest (140+ possible dungeons)
 
Almost any dungeon or dragon lair that contains a word wall (30+ possible locations)
 
Meridia's Beacon, needed at the start of the quest, can be located in nearly any location that contains a boss chest (150+ possible locations)
 
Many dungeons, dependent on the hold from which you receive the quest (30+ possible locations)
 
Almost any dungeon or dragon lair that contains a word wall (30+ possible locations)
 
Many dungeons that have a boss chest (33 possible dungeons)
 
Most dungeons that have a boss enemy (115+ possible dungeons)
 
Any Dragon lair, dragon priest lair, draugr crypt, Falmer hive, Forsworn camp, hagraven nest, vampire lair, or warlock lair.

Houses
 
Most houses (not inns) occupied by regular citizens (40+ possible houses)
 
All wealthy homes (25+ possible houses)
 
All wealthy homes (25+ possible houses)
 
All wealthy homes (25+ possible houses)

Stores/businesses
 
Most stores with a strongbox (25+ possible stores)
 
Most stores with a ledger (25+ possible stores)

Quest NPCs
Most radiant quests only involve a limited number of NPCs.  In some cases, there may be a few different quest-givers, in which case those quest-givers are listed on each quest page, and the quest is listed under each NPC's list of related quests.

However, cases where any one of a large number of possible randomly chosen NPCs are listed here.  These quests are not listed on each possible NPC page.  Note that quests tied to the NPC's home (rather than specifically to the NPC) are listed under Quest Locations.

Quest Givers
 
Any Orc living in an Orc Stronghold
All Bounty Quests
Any innkeeper, jarl, or steward

Quest Targets
 
Most regular town citizens who have a home (60+ possible NPCs)
 
Many citizens living in cities (55+ possible NPCs)
 
Most citizens in the game (400+ possible NPCs)
 
Most citizens in the game (for the initial target, the person who gives the location of the vampire)
 
Any NPC with a relationship rank of at least 1 with you and is not part of any of the factions excluded from selection
 
Most citizens in the game (235+ possible NPCs)
 
Most citizens living in a major city

World Interactions triggered by NPCs
 
An NPC whose enemy you have killed (70+ possible NPCs)
 
Any NPC whose relative you have murdered
 
 
Any NPC from whom you steal, even if you are not caught

NPCs and Creatures
Many NPCs and creatures have characteristics that are randomly generated.  Although past Elder Scrolls games have used leveled lists to generate generic enemies, in Skyrim that ability now extends to named and unique characters.

For example, Krev the Skinner is the boss bandit for the quest The Silver Hand.  Although he or she will always be a bandit, Krev's race is randomly determined from a leveled list of possible bandit bosses.  In this case, even Krev's gender is randomly determined.

Notes
The radiant location of some quests is determined upon game start, not when the quest appears in your log, meaning you cannot reload an old save to reroll a different location.
Similarly, some quests are activated immediately upon completion of the previous one, before you claim your reward, so only reloading a save from before that will give a different target; simply reloading before speaking to the quest-giver won't (i.e. you will have to complete another radiant quest before you can see what target has been selected for the next quest). 
NPCs and locations added by mods or add-ons can be assigned as targets or givers in radiant quests if they fit the parameters for the given quest.
If a quest has been assigned to a target on Solstheim  or any other new lands added by mods, there will be no quest markers while you are on mainland Skyrim, and the same is true in reverse (if you are on Solstheim or a new land, there will be no markers pointing to Skyrim).
Randomly generated quest locations do not take your character's level into account, so it is possible to be given a radiant quest target in a dungeon that has a minimum level well above yours.