NationalLibraryOfScotland/medical-history-of-british-india huggingface dataset:
44
IV — contd.
CONTROL CASES.
TREATED CASES.
N u m b e r o f p a t i e n t s
T h e i r p r o p o r t i o n t o t o t a l ( p e r c e n t ) .
N u m b e r o f d e a t h s
M o r t a l i t y p e r c e n t a g e N u m b e r o f p a t i e n t s
T H e i r p r o p o r t i o n t o t o t a l ( p e r c e n t ) .
N u m b e r o f d e a t h s
M o r t a l i t y p e r c e n t a g e
IV— contd.
Condition of patients
throughout the treat-
ment—contd .
TOTAL
.
59
. . .
41
. . .
64
. . .
46
. . .
Pulse.
Patients admitted
with pulse above
100 in a minute,
who lived for more
than 48 hours, and
in whom the
number after first
application of
treatment reached
maximum.
Within 24 hours
8 13.55
3
37.50
13 20.31
6
46.15
Later than 24
hours
.
.
51 86.44
38
74.50
51 79.68
40
78.43
TOTAL
.
60
...
42
. . . 63
...
45
. . .
Respiration.
Patients admitted
with more than
28 per minute, who
lived for more
than 48 hours, and
in whom the num-
ber recorded
after first applica-
tion of treatment
reached maxi-
mum.
Within 24 hours
Later than 24
hours.
6
54
1 0 . 0
9 0 . 0
2
40
33.33
74.07
1 1
52
1 7 . 4 6
82.53
6
39
54.54
75.0
Temperature.
Patients who ulti-
mately recovered,
and who after their
temperature had
reached normal
had a secondary
rise to above 99°F.
within a fortnight
of their admission.
.....
9
45.0
...
. . .
6 28.57
. . .
. . .
45
IV—concld.
Highest temperature, pulse, and respiration of all recovery cases (Treated and Controls).
CONTROL CASES.
TREATED CASES.
Highest
temperature.
Highest
pulse.
Highest
respiration.
Highest
temperature.
Highest
pulse.
Highest
respiration.
IV —concld.
Condition of patients through-
out the treatment—concld.
Temperature — concld.
The highest temperature, pulse
and respiration recorded in
discharged patients.
103.0
154
52
103.0
148
52
101.6
158
40
99.o
134
40
103.6
18o
6o
98.8
104
28
101.5
160
44
103.4
104
33
99.8
104
45
103.5
140
48
103 . 6
126
42
103.8
126
30
103.8
146
40
104'6
123
36
102.6
118
30
104.0
140
48
104.0
164
40
101.6
126
40
101.8
128
40
103.2
120
40
102.0
128
34.
103.6
134
46
102.6
124
40
102.6
140
40
104.6
150
45
103.0
112
36
104.4
158
44
103.6
140
36
103.0
128
34
100.4
116
28
103.6
140
48
100.6
108
30
1 0 1 . 8
120
32
102.0
120
37
104.4
134
40
104.4
140
41
102.0
1 0 8
28
103.6
124
34
102.2
120
52
104.0
148
40
. . .
. . .
. . .
102.4
I16
28
Average
.
102.8
138
41
102.6
127
37
V.
Doses of serum injected.
Initial dose given.
Total number
of
patients.
Deaths.
Mortality
percentage.
Average stay
in hospital
before death
(in days).
Recoveries .
Average
s t a y
in hospital
before dis-
charge (in
days).
10 c.c.
.
.
.
4
3
75. 0
4'16
1
28
20 "
. . .
19
14
73.68
5.03
5
40
46
V.
Doses of serum injected—contd.
Initial dose given.
Total numbe
of
patients.
Deaths.
Mortality
percentage.
Average stay
in hospita
l
before death
(in days).
Recoveries.
Average stay
in hospital
before dis-
charge (in
days).
25 c.c.
.
.
.
1
. . .
. . .
. . .
1
66
30 ,,
. . .
56
45
80.35
2.96
1 1
41.54
40 ,,
.
.
.
20
17
85.o
4.29
3
6 0 . 0
5o „
.
.
3
3
100.0
0.33
. . .
...
6o „
. . .
6
6
100.0
0.41
...
...
I00 .,
. . .
I
I
100.0
0.16
...
. . .
Amount of serum injected.
Amount of serum given.
Total number
of
patients.
Deaths.
Mortality
percentage.
Average stay
in hospital
before death
(in days).
Recoveries.
Average stay
in hospital
before dis-
charge (in
days).
20 C.C.
.
3
3
1 0 0 . 0
0.50
. . .
. . .
30 ,,
.
.
1
1
100.0
0.50
...
...
50 „
.
42
33
78.57
4.09
9
50.64
60 ,,
.
6
6
100.0
0.41
. . .
...
70
,,
.
32
26
81.25
2.61
6
39.0
80 „
.
5
2
40.0
1.25
3
61.0
100 „
.
.
6
5
83.33
1 . 9 0
1
43.0
1 1 0
„
. 0
1
1
100.0
0.50
. . .
. . .
120 „
.
.
9
9
1 0 0 . 0
4.11
...
. . .
Over 130 c.c.
.
.
5
3
60.o
1 2 . 0
2
28.50
47
REPORT ON A SERIES OF 70 CASES OF PLAGUE TREATED WITH
BRAZIL'S ANTI-PLAGUE SERUM.
BY W. M. HAFFKINE, C.I.E.,
Director-in-Chief, Plague Research Laboratory,
AND
W. G. WEST, M.R.C.S. (Eng.), L.R.C.P. (Lond.), M.D. (Geneva),
Attached to the Laboratory.
T HE serum used in this series of cases was prepared by Dr. Vital Brazil,
Director of the State Sero-therapeutic Institute of San Paulo, Brazil,
and sent out for trial by the Secretary of State in August 1903.
The serum was supplied in sealed test-tubes each containing about 20 c.c.
Of these, 600 were received and stored in an ice-box till February, when a
sufficient number of patients began to come to the hospitals. The patients
treated were those admitted to hospital between the 10th of February and the
end of March 1904. Fifty were treated in the Maratha Municipal Plague
Hospital (in charge of Dr. N. H. Choksy) and 20 in the Modikhana Municipal
Plague Hospital (in charge of Dr. D. A. Turkhud). These medical men were
responsible for the ordinary symptomatic treatment, which was used for all
cases whether or not they also received the serum treatment.
Every alternate patient received serum treatment, the others being kept to
serve as controls. In the Modikhana hospital, which received a somewhat
different class of patients, several (79, with a subsequent mortality of 67.1 per
cent.) refused to undergo the serum treatment. In such circumstances the
serum was offered to the next patient admitted until one was found willing to
undergo the treatment, when the next case was taken as a control case. This
did not disturb the experiment to any extent ; but more difficulty was found with
patients admitted with no definite symptoms of plague. These had to be kept
separate till a definite diagnosis was arrived at. The procedure was thus the
same as in the trial of Terni's serum ( vide p. 37).
The serum injections, which in all cases were hypodermic, were given by
one of us (W. G. West), who was likewise responsible for the correctness of the
history of each patient, as observed by him at the hospitals.
The initial dose injected was 40 c.c. in all the cases (20 in number) treated
in the Modikhana Hospital, while in the Maratha Hospital two cases received
20 C.C., six received 40 c.c., while the remainder (42) got 60 c.c. The doses
were repeated once in 24 hours, so that those who lived for some time, or
recovered, received as much as 340 to 360 c.c. in some cases. This method
48
of administration was generally in accordance with the instructions sent by
Dr. Brazil.
The tables below show the results obtained in the two hospitals :—
MODIKHANA HOSPITAL.
No. of patients.
Deaths.
Percentage of mortality.
Serum-treated
.
.
.
.
. 20
17
85
.
. .
.
Control cases. 20
15
75
MARATHA HOSPITAL
No. of patients.
Deaths.
Percentage of mortality.
Serum-treated
. . • • • 5 0
41
82
Control cases
.
.
.
.
.
5 0
45
90
The small difference in these results, in one case in favour of the controls,
and in the other in favour of those treated with serum, would appear to be.
accounted for by the chance inclusion (Table II) of a few more serious cases
on the one side than on the other.
In both hospitals the serum appears in several cases to have acted by
reducing the temperature and pulse-rate within the first few hours after admis-
sion. In the Maratha Hospital the rate of breathing was reduced also in some
cases. In the Modikhana Hospital these cases showed a greater mortality than
the control cases, while in the Maratha Hospital the contrary was the case.
In both hospitals the fatal serum cases lived longer than the fatal control
cases. In the Modikhana Hospital, where the serum-treated cases showed a
higher mortality than the controls, they lived on the average 2.55 days longer.
In the Maratha Hospital, where the serum-treated cases showed a lower morta-
lity than the controls, they lived on the average only 7½ hours longer.
As regards the few recovery cases, the normal state as regards temperature,
pulse and respiration was sooner attained in the case of the serum-treated cases
than in the controls in the Modikhana Hospital, while in Maratha Hospital the
reverse was the case.
The type of case admitted to hospital during the time of trial of the serum
was severe, but the above does not warrant us in ascribing to the treatment
any measure of influence on the course of the disease.
49
Analysis of one hundred hospital charts referring to so patients treated with Dr.
Brazil's plague curative serum and 50 alternate cases observed as controls in the
Maratha Municipal Plague Hospital, Bombay, under Dr. N. H. Choksy, in 1904—
CONTROL CASES.
TREATED CASES.
N u m b e r o f p a t i e n t s . Number of deaths.
M o r t a l i t y p e r c e n t a g e .
A v e r a g e s t a y i n
h o s p i t a l b e f o r e
d e a t h ( i n d a y s ) .
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
Aver age st ay i n
hospi t al bef or e
deat h( i n days) .
I.
Previous History.
Patients who stated
they had been ill
before admission
for—
I day
.
.
1
0
. . .
...
1
1
1 0 0
2.00
2 days
.
.
1 0
9
90
2.63
12
10
83.33
2.80
3 days
.
.
13
13
1 0 0
2.66
17
15
88 . 23
2.43
More than 3
days.
19
16
84.21
2.13
16
12
8 0
3.09
An unknown
time.
7
7
1 0 0
1.21
4
3
75
1.26
Total of patients
admitted.
5 0
45
9 0
2.25
50
41
82
2.56
II.
CONTROL CASES.
TREATED CASSE.
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
A v e r a g e s t a y i n h o s -
p i t a l b e f o r e d e a t h
( i n days) .
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
A v e r a g e s t a y i n h o s -
p i t a l b e f o r e d e a t h
( i n d a y s ) .
II.
State on admission.
General condition of
patients—
Moribund
.
I0
10
100
.55
1 0
10
1 0 0
'50
Neither moribund
nor convalescent
40 .
35
87. 50
2 . 8
40
31
77.50
2.46
Drowsy, coma-
tose or un-
conscious.
21
21
I00
2.47
22
19
86.36
3.15
Not in above
condition.
19
14
73•68
3.42
18
12
66.66
3.36
50
CONTROL CASES.
TREATED. CASES.
Nu mb e r o f p a t i e n t s .
Nu mb e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
Av e r a g e s t a y i n h o s -
p i t a l b e f o r e d e a t h ( i n
days).
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
Mortality percentage
Av e r a g e s t a y i n h o s -
p i t a l b e f o r e d e a t h ( i n
days).
II—contd.
State on admission
contd.
Temperature.
Patients who had, on
admission, a tern-
perature of—
Below 99º F
...
...
. . .
...
4
2
50
0.2
99—100.9°
.
7
6
85.71
2.33
7
7 100
2.21
101 —102.9°
.
19
16
84.21
2.75
19
16
84.21
2.40
103—104.9°
.
22
21
95.45
2.16
20
16
80
2.93
Above 105°
.
2
2 100
. . .
. . .
...
. . .
. . .
TOTAL
.
..
...
...
. . . ...
...
...
...
Pulse-rate.
Patients whose pulse,
on admission, was,
per minute,—
90 and below .
...
...
...
...
2
1
50
...
91—120 .
.
25
21
84
2.21
.20
16
80
4.25
121—150 .
.
23
22
95.65
2.36
22
1 8
81.81
1 . 9 7
Above 151
.
2
2 100
.50
6
6 100
.66
T OTAL
.
...
...
...
...
. . .
. . .
. . .
Respiration.
Patients whose re-
spiration, on ad-
mission, was, per
minute,—
35 and less
. 24
19
79.16
2.44
30
22
73.33
3.11
36—50
. . 26
26 100
2.19
20
19
95
2.05
Above 51
.
. . .
. . . .
. . .
. . .
. . .
...
. . .
. . .
TOTAL
.
...
. . .
. . .
. . .
. . .
. . .
. . .
. . .
Buboes.
Patients in whom
buboes were found,
on admission, or
later, to be—
.
Present .
. 50
45
90
2.25
50
41
82
2.56
Single
.
.
12
10
83.33
2.20
8
6
75
2.33
Maxillary, single
...
...
. . .
. . .
. . .
...
. . .
.
. . .
Parotid
7,
.
. . .
...
. . .
. . . .
...
... ...
. . .
Cervical
„ .
. . .
. . .
. . .
. . .
2
2
100
4
Axillary
„ .
9
8
88.88
2.25
5
3
6 0
2
Iliac
,, .
. . .
. . .
. . .
. . . .
1
1
1 0 0
. . .
Inguinal
, , .
...
. . .
. . .
. . .
. . .
. . .
. . .
. . .
51
CONTROL CASES.
TREATED CASES.
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
A v e r a g e s t a y i n
h o s p i t a l b e f o r e d e a t h
( i n d a y s ) .
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
A v e r a g e s t a y i n h o s -
p i t a l b e f o r e d e a t h
( i n d a y s ) .
II—concld.
Femoral, single.
3
2
66.66
2
. . .
. . .
. . .
. . .
State on admission —
concld.
In other situa-
tions, single.
...
. . .
. . .
. . .
. . .
...
. . .
. . .
Buboes.
Multiple .
. 38
35
92.10
2.20 42
35 83.33
2.67
Patients in whom
buboes were found,
on admission, or,
later, to be—
Multiple, neigh-
bouring.
27
25
92.55
2.26 34
29
85.26
2.67
Multiple, oppo-
site.
2
2 100
2.
4
4
1 0 0
1 . 8 8
Multiple, scat-
tered.
9
8
88.88
3
4
2
50
4.25
Absent altoge-
ther.
...
. . .
. . .
. . .
. . .
. . .
. . .
. . .
0 days after .
1
1
1 0 0
. . .
. . .
. . .
. . . ...
Microbes in blood.
1 day „
.
6
6
1 0 0
1.25
4
4 100
1.38
Patients examined in
whom microbes
were found, on ad-
mission to hospital,
to be present and
who lived for—
2 days „
.
2
2 100
2
4
4 100
2.0
3 and more after
6
6 100
3.75
5
5
1 0 0
4.10
Recovered
.
. . .
. . .
...
. . . . . .
. . .
. . .
. . .
Microbes not
found in.
27
22
81.48
2.50
24
15
62.15
2.13
Not examined
8
8
1 0 0
1.82
13
13 100
3.19
Males .
.
44
39 88.63
2.35
40
31
77.50
2.37
Females .
.
6
6
1 0 0
1.83
10
10
1 0 0
3.4
Up to 10 years
of age.
3
2
66.66
1.25
2
1 5 0
1.5
11—25 .
.
30
27 90
2.70
29
22
81.48
2.61
Sex, age, caste
and nationality
26—45
.
15
1 4 93.33
1.82
15
14
93.33
2.32
Above 45
.
2
2
1 0 0
1.5
4
4 100
3.63
Among the patients
there were—
Hindoos .
.
41
37 90.24
2.31
38
34
89.47
2.83
Mahomedans .
5
5 100
2.90
10
6 6 0
1.33
Goanese and
Native Chris-
tans.
4
3 75
1 . 1 6 2
1
50
1.50
Parsis .
.
. . .
. . .
...
. . . . . .
. . .
... ...
Europeans and
Eurasians.
...
. . .
...
. . .
. . .
. . .
. . .
. . .
H 2
T. .
•
. .
52
I I I .
CONTROL CASES.
TREATED CASES.
N u m b e r o f p a t i e n t s .
T h e i r p r o p o r t i o n t o
t o t a l ( p e r c e n t a g e ) .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
A v e r a g e e x t e n t o f
i n c r e a s e o r d e c r e a s e .
N u m b e r o f p a t i e n t s . T h e i r p r o p o r t i o n t o
t o t a l ( p e r c e n t a g e ) .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e . A v e r a g e e x t e n t o f
i n c r e a s e o r d e c r e a s e .
III.
Condition of patients
after first application of
treatment.
Lived for more than
24 hours . . .
. . .
45 90
40 88.88
. . . 45
90 36
8 0
. . .
Temperature.
Total admitted with 100°F
. and over, who lived
for more than 24 hours.
. . .
37
... 32 86.49 ... 34 ... 27 79.41 ...
Patients admitted with
temperature above
1 0 0° F . , i n w h o m t h e
next temperature,
recorded after
treatment (or, in
controls, after
admission), showed—
Increase .
. 19 51.35 16 84.21 1.41 10 29.41 9 90
1.42
Decrease
. 18 48.65 16 88.88 2.41 20 58.32 15 75
2.62
Stationary
condition
. . .
...
. . .
...
. . .
4 11.76 3 75
. . .
Pulse.
Total admitted with pulse
above 100 a minute, who
lived for more than 24
hours
.
.
. . .
36 ... 32 88.89 ... 33 ... 26 78.78 ...
Patients admitted with
pulse above 100 a
minute, in whom the
next number, recorded
after treatment (or,
in controls, after
admission), showed—
Increase .
. 18 50
6 88.88 8.66 9 27.27 8 88.88 9.90
Decrease
. 1 5 41.67 14 93.33 5.60 19 57.58 14 73.68 9.60
Stationary
condition
. 3 8.33 2 66.66 ...
5 15.15 4 8 0
...
Respiration.
Total admitted with more
than 28 a minute who
lived for more than 24
hours
.
.
.
. . .
37 ... 32 86.49 ... 33 ... 26 78.79 ...
Patients admitted with
more than 28 in a
minute, in, whom the
next number, recorded
after treatment (or, in
controls,after admis-
sion), showed an—
Increase .
. 15 40.54 13 86.66 2.40 15 45.45 12 80
3.31
Decrease
. 12 32.43 12 100
4.40 13 39.39 9 69.23
5.39
Stationary
condition
.
1 0 27.03 7 70
. . .
15.15 5 100
. . .
53
IV.
CONTROL CASES.
TREATED CASES.
N u m b e r o f
p a t i e n t s .
T h e i r p r o p o r -
t i o n t o t o t a l
( p e r c e n t a g e ) .
N u m b e r o f
d e a t h s .
M o r t a l i t y
p e r c e n t a g e .
N u m b e r o f
p a t i e n t s .
T h e i r p r o -
p o r t i o n t o
t o t a l ( p e r -
c e n t a g e ) .
N u m b e r o f
d e a t h s .
M o r t a l i t y
p e r c e n t a g e .
IV.
Condition of patients
throughout the treatment.
Temperature.
TOTAL
.
25 ...
20 80.0
23
. . .
16
69.56
Patients admitted with
temperature above
1 0 0°F . , w h o l i v e d f o r
more than 48 hours,
and in whom the tem-
perature, after the first
application of treat-
ment or, in controls,
after admission), reach-
ed maximum—
Within 24 hours
16
64
12 75
14
60.87
9
64.28
Later than 24
hours.
9
36
8 88.88
9
39.13
7
77.77
TOTAL
. 25
. . .
20
8 0
23
. . .
16
69.56
Pulse.
Patients admitted with
pulse above 100 in a
minute, who lived for
more than 48 hours,
and in whom the num-
ber, after first applica-
tion of treatment (or, in
controls, after admis-
sion),reached maximum.
Within 24 hours
15
60
1 0 66.66
16
69.57
13
81.25
Later than 24
hours.
10
40
1 0 100
7
30.43
3
42.85
TOTAL
.
24
. . .
19 79.17
23
. . .
16
69.56
Respirations.
Patients admitted with
more than 28 per min-
ute, who lived for more
than 48 hours, and in
whom the number re-
corded, after first appli-
cation of treatment
(or, in controls, after
admission), reached
maximum—
Within 24 hours
10 41.67
6 6 0
8
34.78
6
75
Later than 24
hours.
14 58.33
13 92.85
1 5 65.22
1 0 66.66
Temperature.
Patients who ultimately
recovered and who, after
their temperature had
reached normal, had a
secondary rise above
99° F. within a fortnight
of their admission
. . .
. . .
. . .
. . .
. . .
4
9.76
. . .
. . .
Pulse.
Patients who ultimately
recovered and who, after
their pulse-rate became
normal, had a relapse to
above 90 in a minute
. . .
. . .
. . .
. . .
...
4
9.76 ...
..
Respiration.
Patients who ultimately
recovered and who, after
their respiration became
normal, had a relapse to
above 35 in a minute
. . .
. . .
. . .
. . .
. . .
2
4.88
. . .
. . .
54
V.
Recovery cases: Interval between admission to hospital and the time when the
temperature, pulse, and respiration become normal.
Control cases.
Treated cases.
Temperature
.
.
.
5.90 days
9.64 days.
Pulse-rate . . . . . .
.
5 . 5 5
„
8.42 ,,
Respiration
.
.
6 . 6 6
„
9.42 „
Average stay in hospital of fatal cases.
CONTROL CASES.
TREATED CASES.
2.25 days.
2.56 days.
Doses of serum injected (subcutaneously) into the 50 Patients treated.
Initial dose injected
(in c.c.).
Total quantity injected
(in c.c.).
Number of patients so
injected.
Number of recoveries
among them.
Number of deaths
among them.
20
20
1
...
1
20
40
1
. . .
1
40
40
1
...
1
6 0
6 0
15
...
15
20
80
1
1
. . .
40
100
1
...
1
4 0
120
1
...
1
6 0
120
8
...
8
20
140
1
1
. . .
6 0
1 8 0
5
. . .
5
6 0
200
1
. . .
1
6 0
240
4
. . .
4
40
260
1
1
. . .
6 0
260
1
1
. . .
6 0
280
3
2
1
60
340
2
2
. . .
6 0
350
1
...
1
6 0
360
2
1
1
55
Analysis of Forty clinical charts referring to 20 patients treated with Dr. Brazil's
plague curative serum and 20 alternate cases observed as controls, in the Modikhana
Municipal Plague Hospital in Bombay, under Dr. Turkhud, in 1904.
I.
CONTROL CASES.
TREATED CASES.
N u m b e r o f
p a t i e n t s .
N u m b e r o f
d e a t h s .
M o r t a l i t y
p e r c e n t a g e .
A v e r a g e s t a y
i n h o s p i t a l
b e f o r e d e a t h
( i n d a y s ) .
N u m b e r o f
p a t i e n t s .
N u m b e r o f
d e a t h s .
M o r t a l i t y
p e r c e n t a g e .
A v e r a g e s t a y
i n h o s p i t a l
b e f o r e d e a t h
( i n d a y s ) .
I.
1 day
.
.
3
2
66.66
.66 ...
. . .
. . .
. . .
Previous history.
Patients who stated
they had been ill
before admission
for—
2 days .
5
1 20
3.50
4
4 100
7.25
3 days .
4
4
1 0 0
2.87
8
6 75
3.58
More than 3 days
8
8
1 0 0
1.75
7
6
85.71
4 . 2 5
An unknown
time
. . ...
. . .
. . .
...
1
1
1 0 0
2.5
Total of patients
admitted
20
15 75
2.06
20
17 85
4 . 6 1
II.
II.
Moribund
.
3
3
100
.66
3
3
1 0 0
.66
State on admission.
Convalescent .
. . .
. . .
. . .
. . . . . .
. . .
. . .
. . .
General condition of
patients.
.
Drowsy
.
7
5
71.42
2.10
8
3
1 0 0
3.67
Comatose
. ...
...
...
...
1
1
1 0 0
1
Unconscious .
2
2 100
2.25
1
1
1 0 0
3 . 5
Not in above
condition
8
5
62.50
2.80
7
4
57.14
6.12
Temperature.
Below 99° F. .
1
1
100
3.50
1
1
1 0 0
3.50
P a t i e n t s w h o h a d ,
on admission, a
temperature of—
99—100.9° F. .
2
2
100
2.25 ...
. . .
...
...
101—102.9° F. 10
7
70
2.57
10
9
90
4.11
1 0 3°
and above
7
5
71.45
1.60
9
7
77.77 5 . 4 2
Pulse-rate.
90 and below . ...
. . .
...
. . .
1
1 1 0 0
2.5
Patients whose pulse,
on admission, was,
per minute,—
91—120
. 13
1 0 76.92 1.95
4
2 50
1 . 5 0
121—150
7
5
71.42
2.3
15
14
93.33
5.17
Above 151
. ...
. . .
...
. . . . . .
. . .
. . .
. . .
Respirations.
35 and less
. . 17
13
76.47
2.15
16
13 81.25
5.34
Patients whose
respiration, on
admission, was per
minute,—
36—50 .
. .
3
2
66.66
1.50
4
4 100
2.35
Above 51 .
. . .
. . .
. . .
...
. . . . . .
. . .
. . .
56
CONTROL CASES.
TREATED CASES.
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
A v e r a g e s t a y i n h o s -
p i t a l b e f o r e d e a t h(
i n d a y s ) .
N u m b e r o f p a t i e n t s . N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e . A v e r a g e s t a y i n h o s -
p i t a l b e f o r e d e a t h
(in days).
Present .
.
18
14
77.77
2.07
20
17
85
4.61
Single .
.
12
9
75
2.05
10
8
8 0
6.62
II—contd.
Maxillary, single ...
...
...
. . .
. . . ...
. . .
. . .
State on admission.
Cervical „ . ...
...
. . .
. . .
. . . ...
. . .
. . .
Buboes.
Axillary „ .
4
4 100
2.50
5
3
6 0
1.83
Patients in whom
buboes were
found, on admis-
sion or later on,
t o b e —
Iliac
, ,
.
1
1 100
2.50
1
1 100
20
Inguinal „ .
2
1 50
1.5
. . . ...
. . .
. . .
Femoral ,, .
4
3
75
1.50
2
2 100
3.25
Parotid
,, .
1 ...
...
. . .
2
2 100
10.5
Multiple „ .
6
5
83.33
2.10
1 0
9
9 0
2.83
Multiple, neigh-
bouring
.
3
2
66.66
2.75
8
8 100
2 . 7 4
Multiple, opposite ...
...
. . .
. . .
...
...
. . .
. . .
Multiple, scat-
tered .
3
3 100
2
2
1
50
3.50
Absent alto-
gether .
2
1
50
1
...
...
. . .
. . .
Microbes in blood.
Patients examined
in whom microbes
were found, on
admission to
hospital, to be—
Present .
5
5 100
2.20
4
4 100
2.35
Absent
5
2
40
2.50
4
3
75
3.62
Males up to —
15 years of age
5
4
80
2.87
1
1
1 0 0
7
16—20
6
3
50
2.16
6
6 100
7.41
21—40
7
6
85.71
1.70
8
6
75
2.66
Sex, age, caste,
nationality.
Above 41
1
1
100
1.50
2
2 100
4.50
Females up to —
15 years of age ...
...
. . .
. . .
1
. . .
. . .
. . .
Among the patients
there were—
16—20
.
1
1 100
3
. . .
...
. . .
...
21—40
. ...
...
. . .
...
1
1
1 0 0
1
Above 41
.
. . .
. . .
. . .
...
1
1
1 0 0
1
Hindoos
.
1 1
7
63.63
1.92
1 1 10
9 0 . 9 0 4.65
Mahomedans .
3
3
100
1.66
2
1
50
...
Goanese and
Native Chris-
tians .
6
5
83.33
2.50
7
6
85.71
5.33
57
CONTROL CASES.
TREATED CASES.
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
A v e r a g e e x t e n t o f i n c r e a s e o r d e c r e a s e .
N u m b e r o f p a t i e n t s .
N u m b e r o f d e a t h s .
M o r t a l i t y p e r c e n t a g e .
A v e r a g e e x t e n t o f i n c r e a s e o r d e c r e a s e .
III.
Condition of patients
after first applica-
tion of treatment.
Temperature.
Patients admitted
with temperature
above 99° F., in
whom the next tem-
perature, recorded
after treatment (or,
in controls, after
admission), showed
an—
Increase .
.
12
10
83.3
1.4
1 0 8
8 0
1 . 1
Decrease .
.
3
1
33.3
1.4
8
7
87.50
2.05
Stationary Con-
dition .
.
3
2
66.6
...
...
...
...
. . .
Pulse.
Patients admitted
with pulse above
100 a minute, in
whom the next
number recorded
after treatment (or
in controls,after ad-
mission), showed—
Increase
.
1 3
9
69.1
1 1 . 3
8
8
1 0 0
10.7
Decrease
.
3
2
66.66
12.6
5
5
1 0 0
1 0 . 6
Stationary con-
dition
. .
1
1 100
...
2
1
50.0
. . .
Respiration.
Patients admitted
with more than
28 a minute, in
whom the next
number recorded
after treatment (or,
in controls, after
admission), showed
an—
Increase .
.
2
2
1 0 0
6
1
1
1 0 0
1 0
Decrease .
.
3
2
66.6
8.3
2
2
100
6
Stationary Con-
dition
.
.
1
1
100
...
. . .
. . .
. . .
. . .