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September 27 th—Morning.—Pulse 60, respirations 10, temperature 104. No urine kept.
Refuses grain, eats grass, is very thirsty. . The dirty yellow color and petechias which is
characteristic in the conjunctiva of this disease are also very marked in the mucous membrane of
the vagina of this mare.
Evening.—Pulse 62, respirations 30, temperature 105. Urine, specific gravity 40, no
albumen, alkaline, color normal. Refuses grain, eats grass slowly. Does not lie down. I am
told that the patients suffering from this disease seldom do lie down night or day.
September 28ih—Morning.—Pulse 49, respirations 8, temperature 1011/5. Œdema at the
sternum; off feed; thirsty, mouth moist. Urine, alkaline and contains much albumen, specific
gravity 38, high colored.
Evening.—Pulse 62, respirations 16, temperature 104 4/5. (Edema at the sternum increased.
Urine, specific gravity 26, albuminous, less color.
September 29th—Morning.—Pulse 50, respirations 10, temperature 100 3/5. Urine, specific
gravity 34, albuminous, alkaline, color normal. No parasite found in a drop of blood taken
from the off-side of the neck; but one, very active, found in a drop taken from the near side.
Œdema extending backwards from sternum. Patient was down for two hours last night; showed
no pain.
Evening.—Pulse 56, respirations 32, temperature 103 2/8. Fed up 6 lb. of grain and full-
allowance of grass.
September 30th—Morning.—Pulse 60, respirations 12, temperature 101. (Edema increasing.
Feeding. Urine not examined. No evening examination was made. I was too busy in making
a, post-mortem examination and inspecting horses coming in from the outposts.
October 1st—Morning.—Pulse 54, respirations 14, temperature lOl 3/8 Urine, specific gravity
32, albuminous and alkaline. Fed up yesterday 8 lb. of grain and grass.
Evening.—Examination not made, too busy otherwise.
October 2nd—Morning.—Pulse 60, respirations 14, temperature 104 1/5. Œdema increasing.
Urine, specific gravity 32, alkaline, albuminous. Fed 6 lb. of grain yesterday besides the grass.
She has fallen off in condition wonderfully.
October 3rd—Morning.—Pulse 58, respirations 18, temperature 102 3/5. Urine not examined.
October 4th—Morning.—Pulse 62, respirations 14, temperature 103. Fed up 8 lb. corn
yesterday besides the grass. One drop of blood examined, only one parasite found.
October 5th—Morning.—Pulse 64, respirations 14, temperature 103. Fed up yesterday nearly
8 lb. grain. Submaxillary glands very tender and enlarged.
October 6th—Morning.—Pulse 65, respirations 20, temperature 102 4/5. Submaxillary gland
more enlarged and very tender; the pulse has to be felt at the heart. Passing urine frequently,
color light, not able to examine it further. Œdema of hind legs increasing.
October 7th—Morning.—Pulse 66, respirations 13, temperature 102 1/5. A great number of
parasites found in a drop of blood. Fed only 4 lb. of grain yesterday. Is wasting to a
skeleton.
October 8th—Morning.—Pulse 60, respirations 22, temperature 103 2/5. Refused grain yester-
day, ate grass.
October 9th—Morning.—Pulse 50, respirations 18, temperature 100 2/5. Ate only 1 lb. of grain
yesterday, and half allowance of grass.
October 16th—Morning.—I returned last night from the outposts and find this mare reduced
to a wretched " bag of bones," though I am told that for the last three or four days she has
eaten 8 lb. of gram daily with the full allowance of grass. Pulse 58, respirations 10, tempera-
ture 100 2/5. Œdema has disappeared from the body and fore legs, but continues in the hind
legs. One drop of blood examined, no parasite found. The white corpuscles are in great
numbers. Many of the red corpuscles smaller than normal, look like particles of shapeless jelly ;
there is much granular matter in the serum.
October 18th—Morning.—Destroyed, for post-mortem examination. Very little serum found
in the abdominal cavity; there was a slight velvety fluff of lymph on the parietal peritoneum ;
no inflammation. The kidneys were pale and sodden-like. I had no time to make a section of
these kidneys for microscopical examination. The liver, spleen, heart and lungs were healthy.
The stomach and intestines were opened from end to end and found healthy. A few parasites
were found in the blood.
Remarks.—It should be particularly noted in this case with regard to the life history of the
blood parasites that they do not disappear from the blood absolutely when it becomes difficult to
find one in a drop of blood; but that when one brood or generation dies, there are ova or spores
left for the development of another brood. Thus, in this case, on the 26th September the
parasites were swarming in each drop of blood; on the 29th only one parasite was found in two
drops of blood examined ; on the 4th October one parasite only was found in one drop of blood ;
on the 7th October great numbers were found in a drop (that is there were more than I could
count). I was not able to see the case again from the 9th until the 16th when one drop of blood
was examimed and no parasite found. It should be noted also that this patient was much more
off her feed than is usual in this disease. This is the only case in which the structure of the
kidney did not appear perfectly healthy. I therefore consider it was a coincidence, or what might
be called an accidental occurrence in the case and having no special relation with the disease.