17
and listless. Fifty million stock typhoid vaccine was injected. Two days later, he regained
consciousness and asked for his food. On the 24th and 27th days, 75 and 100 million stock
vaccine was injected, followed by 150 and 200 million autogenous vaccine on the 30th and
33rd days. Recovery after commencing the injections was uneventful except for a bronchitis
which seemed to delay the fall of temperature to normal.
In this case the first injection was unfortunately not given till the 21st day which is
normally the turning point in the course of enteric. How far the vaccine favourably modified
the course of the disease is thus a doubtful point.
Case 15.—One of ulceration of the tongue and mouth diagnosed as sprue. A strepto
-coccus was isolated from the ulcers and the autogenous vaccine injected in six doses of 5 to 20
millions. The ulcers rapidly healed and mastication was painless at the end of the course of
injections which lasted about one month.
TABLE X.
Miscellaneous.
Serial
num-
ber.
Case
num-
ber.
Medical Officer.
Disease.
Vaccine made.
Result.
1
13
Major F. Clarence Smith, I.M.S.,
Madras.
. . .
Staphylococcus albus. Not known.
2
15
Captain E. B. Jones, R.A.M.C., Banga
-lore.
Sprue . . .
Streptococcus . . . Much improv
-ed.
3
24
Chief Medical Officer, Madras and
Southern Mahratta Railway, Madras.
Chronic colitis . . .
B. Coli . . .
Do.
4
29
Assistant Surgeon, Municipal Hospital,
Gooty.
Vaginitis . . .
A. bacillus . . . Not issued.
5
38
Superintendent, Government Mater
-nity Hospital, Madras,
Puerperal sepsis . . .
Streptococcus . . . Not known.
6
46
Major F. Clarence Smith, I.M.S.,
Madras.
Intestinal catarrh . . .
B. Coli . . .
Do.
7
61
Medical Officer, 80th Carnatic Infantry,
St. Thomas' Mount.
Enteric . . .
B. Typhosus . . . Much improv
-ed.
8
76
Do. do.
Do. . . .
Do. . . . Not used.
9
102
Superintendent, Lunatic Asylum,
Madras.
Sapræmia . . .
Streptococcus . . . Not known.
10
108
Superintendent, Government Maternity
Hospital, Madras.
Vaginal discharge . . .
Staphylococcus albus. Not used.
11
112
Medical Officer, 80th Carnatio In
-factory, St. Thomas' Mount.
Colitis . . .
B. Coli . . . Not known.
Stock vaccines.
Polyvalent staphylococcus vaccine was used in cases of boils, abscesses, carbuncles,
eczema and ulcerations and favourable results were obtained by its use in all these different
conditions. Boils were almost invariably benefited by a few injections 50 to 200 million,
whilst the brawny swellings appearing in the course of multiple recurring abscesses have been
reported to have resolved without suppurating.
Polyvalent streptococcus vaccine was employed in cases of diabetic gangrene, cellulitis,
compound fractures, septic wounds and sinuses involving bone and joints and in cases of
puerperal sepsis.
The following interesting case was reported from the Government Maternity Hos
-pital, Madras. The case was one of adherent placenta manually removed 17 days after con
- f i n e m e n t . T h e p a t i e n t ' s t e m p e r a t u r e w a s s t i l l h i g h 9 9°- 1 0 3° F . A f t e r t h e 1 7 t h d a y t h e
patient got rigors and the temperature went up to 106° F and kept high till the 26th day,
when an injection of 10 million streptococcus was given. The same dose was repeated on
the 29th day with the result that the temperature came down to normal in 24 hours and the
patient made a good recovery.
B. Coli vaccine has been reported favourably in cases of cystitis and pyelitis.
Polyvalent pneumococcus vaccine has been used in cases of bronchitis and asthma but
with no definite result.
Gonococcus vaccine .—The polyvalent vaccine issued to the local and mufassal institutions
was very favourably reported upon. Its efficacy in gonorrhœal arthritis and teno-synovitis
was most marked, so much so that in a doubtful case of joint inflammation the favourable
result following the injection with gonococcus vaccine could be assumed to be a bacteriological
test in diagnosing the nature of the arthritis. Conversely a case of rheumatism which does
not yield to gonococcus vaccine is almost certainly a non-gonorrhoeal inflammation and should
be treated with the usual rest, alteratives and anodynes.
5