NationalLibraryOfScotland/medical-history-of-british-india huggingface dataset:
8
a prophylactic cholera vaccine in considerable quantities for the immunization of
units proceeding to Mesopotamia. This vaccine was prepared from a Laboratory
strain whose virulence had been increased by peritoneal passage through guinea-
pigs. A triple vaccine containing 500 million B. Typhosus, 250 million B. Para
- t y p h o s u s A a n d 2 5 0 m i l l i o n B . P a r a t y p h o s u s B , p e r c . c . f o r a f i r s t d o s e a n d o n e
with twice those amounts for a second dose was also issued in some quantity.
The demand for Tuberculin was much less than during previous years as the
Presidency hospitals have stopped using it.
Only 122 autogenous vaccines were prepared and issued during the year.
They were distributed to the different institutions and medical men as under :—
TABLE VI.
(1) The General Hospital, Madras . . .
15
(2) The Royapettah Hospital, Royapettah . . .
3
(3) The Monegar Choultry Hospital, Rayapuram . . .
4
(4) The Government Lunatic Asylum, Madras . . .
5
(5) The Government Maternity Hospital, Madras . . .
7
(6) The Government Ophthalmic Hospital, Madras . . .
2
(7) The Station Hospital, Fort St. George, Madras . . .
1
(8) Private practitioners or medical officers in their private
capacity in Madras City . . .
26
(9) Hospitals and medical men in mufassal . . .
59
Total . . .
122
Details as to the greatly increased issues of bacterial vaccines are shown in—
TABLE VII.
N u m b e r .
Name of organism vaccined.
Number of doses
of autogenons
vaccine.
Number mber of doses
of stock vaccine.
Total.
1 S t r e p t o c o c c u s . . .
189
334
523
2 Gonococcus . . .
23
1,550
1,573
3 Pneumococcus . . .
185
77
262
4 Tuberculin . . .
. . .
691
691
5 Staphylococcus . . .
252
784
1,036
6 Pemphigus streptococcus . . .
17
46
63
7 B. Coli . . .
70
53
123
8 B. Dysenteriæ . . .
. . .
144
144
9 Micrococcus catarrhalis . . .
33
. . .
33
10 Acne bacillus . . .
37
26
63
11 Diphtheroid bacilli . . .
33
. . .
33
12 Cholera vaccine . . .
. . .
6,872
6,872
13 Typhoid vaccine . . .
6
1,236
1,242
14 Triple (Typhoid and Paratyphoid A and B) vaccine . . .
. . .
888
888
15 Compound catarrhal vaccine (Pneumococcus, B.
Influenzae, M. catarrhalis).
9
22
31
Total . . .
854
12,723
1 3 , 5 7 7
Sera from the Lister Institute of London and from the Central Research
Institute, Kasauli, were stocked in the Refrigerating Chamber and distributed as.
under :—
TABLE VIII.
N u m b e r .
Name of serum.
Stock on hand
on 1st January
1916.
Received
during the
year.
Sent out
during the
year.
Balance on
hand on 1st
January 1917.
1 Anti-streptococcus serum . . .
99
344
345
98
2 Anti-tetanic serum . . .
102
379
379
102
3 Anti-diphtheritic serum . . .
67
62
82
47
4 Anti-dysenteric serum . . .
60
. . .
25
35
5 Anti-venomous . . .
. . .
24
19
5
6 Coley's fluid . . .
33
. . .
4
29
T o t a l . . .
361
809
854
316
9
Very large quantities of Anti-rinderpest serum and some other bacterial
products were stocked in the cold room for the Veterinary Authorities, and were
distributed throughout the Presidency on indent.
Educational. — Twenty-two students joined the vaccination class in 1916, but
one of them having died shortly after joining the class, only twenty-one sat for the
examination at the end of the course. All of them obtained qualifying marks.
A further course of instruction in the manufacture, care and handling of
stocked calf vaccine lymph was given to candidates undergoing training for
Second-Class Health Officers. Four candidates attended this class and all passed
the examination held at the end of the course.
Eight Civil Assistant Surgeons were instructed in the technique of anti
-plague inoculation during the year under report.
THE KING INSTITUTE OF
PREVENTIVE MEDICINE, GUINDY,
10 th February 1917.
F. MAITLAND GIBSON, M.B., B.SC.,
Director.
12
TABLE III.
Abscesses, carbuncles and cellulitis.
Serial
num-
ber.
Case
num-
ber.
Medical Officer.
Disease.
Vaccine made.
Result.
1
33 Superintendent,
Government Mater-
nity Hospital, Madras.
Abscess . . . Streptococcus . . .
Not known.
2
40 Dr. A. S. Wilson, Kodaikanal . . . Recurring abscess . . .
Do. . . . Cured.
3
49 Assistant Surgeon
S. P. Sarma,
Municipal Hospital, Tiruvalur.
Abscesses . . . Staphylococcus
aureus.
Do.
4
51 Medical Officer, Municipal Hospital,
Chingleput.
Carbuncle . . .
Do.
Not used.
5
52 Third Surgeon, General Hospital,
Madras.
Cellulitis face . . . Streptococcus . . .
Cured.
6
54 Surgeon, First District, Madras
. . . Multiple abscess . . . Staphylococcus
aureus.
Do.
7
56 District Medical and Sanitary Officer,
Cuddapah.
Carbuncle . . .
Do.
No effect.
8
65 Assistant Surgeon S. P. Sarma, Muni-
cipal Hospital, Tiruvalur.
Multiple abscess . . .
Do.
Not used.
9
71 Superintendent, Royapetah Hospital,
Royapetah.
Abscesses . . .
Do.
Cured.
10
78 District Medical and Sanitary Officer,
Cocanada.
Pyæmic abscess . . . Streptococcus . . .
Do.
11
82 District Medical and Sanitary Officer,
Trichinopoly.
Diabetic cellulitis . . .
Do. . . . Local condi-
tion im-
proved but
patient died
of coma.
12
84 Superintendent, Lunatic Asylum,
Kilpauk.
Abscess of jaw
. . . Staphylococcus
aureus.
Improved.
13
90 Assistant Surgeon S. P. Sarma, Muni-
cipal Hospital, Tiruvalur.
Multiple abscess . . .
Do.
Cured.
14
94 Superintendent, Rayapuram Hospital,
Madras.
Do.
. . .
D o .
Not used.
15
95 Assistant
Surgeon, S. P. Sarma,
Municipal Hospital, Tiruvalur.
Carbuncle . . .
Do.
Died before
full course
of injec-
tions were
given.
Acne .—The acne bacillus was isolated from four out of five cases but the result of
autogenous vaccine treatment could not be traced in three of the cases. Three of the five.
cases were in out-stations, namely one in Ootacamund, one in Bangalore, and a third in Assam.
The medical officers in charge of these cases were instructed to send comedones imbedded in
the depth of soft agar, not only to prevent the growth of the ordinary ærobic organisms but
to preserve the acne comedones from desiccation. Anærobic cultivations were made in broth
from the comedones immediately they reached the laboratory by post, which, in the Assam
case, took as long as five days
TABLE IV.
Acne.
Serial
num-
ber.
Case
num-
ber.
Medical Officer.
Disease.
Vaccine made.
Result.
1
16 Major J. J. Robb, I.M.S., Ootaca-
mund.
Acne . . .
Acne bacillus and
staphylococcus
albus.
Great
but
temporary
improve-
ment.
2
23 Captain S. B. Jones, R A.M.C., Staff
Surgeon, Bangalore.
Do. . . . Stock acne bacillus
and
autogenous
staphylococcus
albus.
Not known.
3
31 Resident Medical Officer, General Hos-
pital, Madras.
Do. . . . Acne bacillus . . . Cured.
4
99 Dr. Hall-Wright, Hoogrijan, Assam . . . Do. . . .
Do. . . . Not known.
5
124 Captain A. J. H. Russell, I.M.S.,
General Hospital, Madras.
Do. . . .
Do. . . . Under treat-
ment.
19
TABLE XIII
Showing the results of tuberculin treatment during the year 1916.
Seat of tuberculosis.
Number of
cases cured.
Number o
f c a s e s
improved.
Number of
cases
unaffected.
Total.
Lungs . . .
2
13
9
2 4
Glands . . .
1
3
. . .
4
Bones and joints . . .
. . .
3
3
6
Kidneys . . .
. . . . . .
1
1
Intestines . . .
. . .
1
. . .
1
Total . . .
3
20
13
36
It is no doubt difficult to judge from the reports received how far the tuberculin by itself
was responsible for the benefit derived by the patients in cases of pulmonary tuberculosis.
In the first place, there is a certain number of cases where the diagnosis of tuberculosis is
made not by actual detection of bacilli in the sputum but by physical examination of the
lungs, by the application of one or more of the tuberculin tests or by, certain signs
a n d
symptoms supposed to be characteristic of pulmonary tuberculosis. It is needless to say that
unless the physician in charge has had a fairly large experience of physical examination,it is quite
possible to make a wrong diagnosis unless tubercle bacilli are actually detected in the sputum.
A positive Von. Pirquet's test, a strong suspicion of the presence of deposit as judged by the
stethescope and percussion, a certain amount of febrile disturbance and emaciation, the
occurrence of hæmoptysis, may be present individually or in combination and yet the case
may not be one of tubercular disease and such being the case, it is n ot difficult to understand
how tuberculin therapy may in certain instances win undeserved credit when the improve
-
ment is really due to general treatment applied to a suspected tubercular but really
non-tubercular case. On the other hand the treatment may be lightly undertaken in an
advanced case of real tuberculosis, in which tuberculin therapy is clearly inapplicable and
certain to bring discredit to the physician and to the tuberculin treatment adopted by him.
The correct estimation of the value of tuberculin therapy is therefore a matter of considerable
difficulty, unless the data are perfectly controlled and the cases judiciously selected.
Leaving a margin for all the errors above indicated it cannot be denied that there is a
percentage of pulmonary cases that are really benefited by the treatment.
The efficacy of tuberculin therapy in ostitis, arthritis, and infection of the kidneys,
intestines and other organs is perhaps more indefinite than in pulmonary tuberculosis.
The following case of intestinal tuberculosis is of some interest
: —
It was a case of tubercular disease of the cœcum treated by the District Medical and
Sanitary Officer, Anantapur. After a few injections the bowel symptoms disappeared, the
patient steadily increased in weight, his general health rapidly improved and he felt he was
quite well. About two months after stopping the treatment, the old symptoms reappeared
but in a mild form. The injections were therefore recommenced and the patient is again
improving rapidly.
20
APPENDIX II.
A NOTE ON NOGUCHI'S MODIFICATION OF THE WASSERMANN TEST.
By Civil Assistant Surgeon T. Sitapati Ayyar, L.M. & S.
In the Annual Report for the year 1912, I described the technique and merits of the
Original Wassermann and its modifications Hecht-Fleming and Levaditis. In the year 1914,
a new modification, in which a mixture of ox-liver extract and syphilitic liver extract was used
for antigen, was tried by me with very good results. A description of the method along with
its advantages over others with a theoretical explanation of the Wassermann reaction was
given in the annual report for the year.
In the Indian Medical Gazette March number of 1916, Captain W. R. Galwey, R.A.M.C.,
has given an account of Noguchi's modification for which the author claims that, since all con
-
stituents used in the test are in known quantities, the fallacies which may occur in other
methods are eliminated.
I have since collected all the materials needed for the Noguchi and subjected some
bloods in parallel experiments to the mixed method conducted in the laboratory as a routine,
and to the Noguchi's modification as described by him. A table of the results obtained is
herewith appended.
TABLE I.
N.B.—Explanation of notations used in the table.
+ + + Complete hæmolysis.
+ Slight lysis of a negligible nature.
+ + Partial but leaning towards complete lysis.
– No lysis.
x Test was not done on account of inadequacy of the materials.
Num-ber.
Date of
examination.
Name .
Noguchi's
method.
Result.
Combined
method.
Result.
Remarks.
1916.
1
22nd Sept.
V.P. . . .
–
Positive ?
–
Positive
strong.
-
-
+
2
Do.
S.A.C. G.H. . . .
+ + +
Negative.
+ +
Negative. Ulceration rectum. No history.
+ + +
3
Do.
Mrs. R. c/o P. . . .
+ + +
Do.
+ +
Do.
+ + +
4
Do.
Mrs. A.P.
G.O.H.
+ + +
Do.
+ + +
Do.
5
Do.
A. G.O.H. . . .
+ + +
Do.
+ +
Do.
+ + +
6
Do.
M. G.O.H. . . .
+ +
Do.
+ +
Do.
+ +
+ + +
7
Do.
R.K. G.O.H. . . .
+ + +
Do.
+ + +
Do.
8
2nd Oct. . . .
P t . c / o M . O . ,C
. H . S e c u n -d
e r a b a d .
–
Positive
weak.
–
Positive
weak.
–
+ +
+ + +
+ + +
9
Do. . . .
C. M. c/o P. . . .
+ +
Negative.
+ +
Negative.
+ + +
+ + +
10
Do. . . .
R. G.O.H. . . .
-
Positive
mode-
rate.
+
Positive
mode-
rate.
Healing ulcer.
Cornea left.
-
+
+
–
11
Do. . . .
B. G.O.R. . . .
–
Do.
–
Do.
Optic neuritis.
-
-
+
+
12
Do. . . .
B. c/o T.S. . . .
+ + Negative.
–
Do.
Had injection of Salvarsan twice, two years
ago. Perforation palate still exists. No
active signs.
+ +
–
+ +
+
21
TABLE I— cont.
Num-ber. Date of examination.
Name.
Noguchi's
method.
Result. Combined
method.
Result.
Remarks.
13
1916.
6th Oct. ... B. c/o P.
...
++
Negative. +++
Negative.
+++
+++
+ + +
14
Do.
... R. G.O.H. ...
+++
Do.
+++
Do.
+++
+++
15
Do.
... N.
...
...
++
Do.
+++
Do.
+++
+++
+++
+++
16
Do.
... H.W.A. c/o P....
+++
Do.
+++
Do.
+++
+++
17 13th Oct. ... J.V.M. c/o
-
Positive
weak.
-
Positive
weak.
Major F.F.E.
-
-
+ + +
+++
18
Do.
... C.A. c/o do.
-
Do.
-
Do.
-
-
+++
+++
19
Do.
... R. R.H. ...
-
Do.
-
Positive
strong.
-
-
++
-
-
20
*
Do.
..
Do.
...
+++
Negative.
-
Positive
moder-
ate.
+ + +
-
-
++
21
Do.
... S.R. c/o P. ...
Positive
moder-
ate.
-
Positive
strong.
-
-
-
-
++
+
22
Do.
... R. c/o Dr. S.
-
Do.
-
Positive
moder-
ate.
Tiruvalur.
-
-
-
+
+++
23
Do.
... D.V.S. c/o T.S.
-
Positive
strong.
-
Positive
strong.
White patches on hand like psoriasis. A
Leucoderma.
-
-
-
-
-
-
24
Do.
... C. c/o O. Kum-
bakonam.
+++
Negative.
+++
Negative.
25
Do.
... S. c/o P.
...
+++
Do.
++
Do.
+++
26
*
Do.
... M. G.O.H.
+++
Do.
-
Positive
m o d e r -
ate.
Syphilis and Gonorrhœa ten years ago.
-
-
+++
27
*
Do.
N. G.O.H.
+++
Do.
-
Positive
weak.
Gonorrhœa one year ago.
+
+++
28
Do.
... D.M. G.O.H.
+++
Do.
++
Negative.
+++
29
*
Do.
... T. G.O.H. ...
++
Do.
-
Positive
strong.
+++
-
-
-
30
Do.
... L. G.O.H. ...
+++
Do.
+++ Negative. Keratitis left eye.
+++
31
*
Do.
... J. G.O.H. ...
+++
Do.
-
Positiev
moder-
ate.
Syphilitic, Iridc-choroiditis and Retinitis.
+++
+
+
+++
32
*
Do.
... C.
... ...
+++
Do.
-
Do.
Early Retinitis Pigmentation.
-
-
+
6
22
TABLE I— cont.
Num-
ber.
Date of
examination.
N a m e .
Noguchi's
method.
Result.
Combined
method.
Result.
R e m a r k s .
1916.
33
*
13th Oct. ... R.A. c/o P. ...
+++
Negative.
-
Positive
moder
-
ate.
-
-
+++
34
*
Do.
... Mrs. R. A . c/o P.
+++
Do
-
Positive
weak. -
++
+++
35 20th Oct. ... T. 1st Dt.
...
-
Positive
strong.
-
Positive
strong.
Periostitis of right femur. History of
secondary syphilis.
-
-
-
-
+++
+
36
*
Do.
... R. G.O.H. ...
++
Negative.
+
Positive
weak.
+++
+
+++
+++
37
Do.
... K.D. G.O.H....
++
Do.
+++
Negative.
++
+++
+++
38
Do.
... K.
...
..
-
Positive
weak.
-
Positive
moder
-
ate.
+
-
+++
-
+++
39
Do.
... B.
...
...
+++
Negative.
+++
Negative.
40
Do.
... S.
...
...
+++
Do.
+++
Do.
41
Do.
... R.R. c/o P. ...
-
Positive
strong.
-
Positive
strong.
Tertian.
-
-
-
-
-
-
42 27th Oct. ... M. c/o M.O.,
Mount.
-
Positive
weak.
-
Positive
weak.
+
-
+++
+++
43
Do.
... J.C.R. ...
...
+++
Negative.
-
Positive
moder
-
ate.
-
-
+++
44
Do.
... J.B.C. c/o Dr.
W.R.G.
-
Positive
strong.
-
Positive
strong.
-
-
-
-
-
-
45
Do.
... M. c/o Dr. B.
+
Positive
weak.
-
Positive
weak -
+
+
++
+++
46
Do.
... Mrs. A. c/o P.
-
Positive
moder-
ate.
-
Do.
-
+
+
+++
+++
47
Do.
... S. c/o T.S. ...
-
Positive
strong.
-
Positive
strong.
-
-
-
-
-
-
48
Do.
... S. G.H. ..
-
Do.
-
Do.
-
-
-
-
-
-
49
Do.
... C.K.S. ...
...
-
Positive
moder-
ate.
-
Do.
Gonorrhœa 20 years ago.
-
-
-
-
+++
50
*
Do.
... S.
...
+++
Negative.
-
Positive
mode r-
ate.
+++
-
-
+++
23
TABLE I—cont.
Num-
ber.
Date of
examination.
Name.
Noguchi's
method.
Result. Combined
method.
Result.
Remarks.
51
1916.
27th Oct. ... S.
...
...
-
Positive
moder-
ate.
- Positive
strong.
-
-
-
-
+
52
**
Do.
... I.M. c/o P. ...
- Positive.
+++
Negative. A small ulcer in tongue.
x
+++
+++
53 3 Nov.
... M. G.H.
...
- Positive
strong.
- Positive
strong
-
-
-
-
x
x
54
Do.
... W.S. G.H. ...
-
Do
-
Do.
Chancre two years ago. Two months ago
rash thickening of right leg and thigh.
Pain in the part.
-
-
-
-
-
55
Do.
... G.N. ...
...
+++
Negative.
+++
Negative. Fever off and on with dry cough.
Von Pirquets reaction negative.
56
Do.
... M. c/o T.S. ...
- Positive
strong.
- Positive
strong.
Ulcer root of penis.
-
-
-
-
-
-
57
Do.
.. M. G.O.R. ...
+++
Negative.
+++
Negative.
58
Do.
... B. G.O.H. ...
+
Positive
weak.
+
Positive
weak.
+
+
++
++
+++
59
Do.
... N. M.H.
...
+++
Negative.
+++
Negative. Syphilis. History six months ago.
60
Do.
... S.G. ...
...
- Positive
weak.
+
Positive
weak.
No History.
-
+
+
++
+++
61
Do.
... C.
- Positive
moder-
ate.
+ Positive
moder-
ate.
-
+
-
++
+++
62
Do.
... V.
...
...
-
Do.
+
Do.
-
+
-
+
+++
+++
63
Do.
... M.
...
...
-
Do.
+
Positive
weak.
-
+
+
+
+++
+++
64
Do.
... C.
...
...
++
Negative.
+++
Negative.
+++
+++
+++
65
Do.
... A.K.R. c/o T.S.
- Positive
strong.
- Positive
strong.
-
-
-
-
+
66
Do.
... A.R. c/o P. ...
-
Do.
-
Do.
-
-
-
-
-
-
67 10th Nov. ... B. 1st District.
- Positive
mode.-
rate.
+
Positive
moder-
ate.
A scar in glans penis. Enlarged glands
in axillæ, cervical region and groin.
Shotty. No history of rashes over body.
-
+
-
++
+++
68
Do.
... J.C.R. c/o Dr.
W.R.G.
+++
Negative.
+++
Negative. Tested on 28th October 1916 with positive
moderate result by combined method. No
clinical signs.
24
TABLE I—cont.
Num-
ber.
Date of
examination.
Na me .
Noguchi's
method.
Result.
Combined
method.
Result.
Remarks.
1916.
69 10th Nov. .. M.B.G. c/o Dr.
+
Positive
strong.
+
Positive
weak.
W.R.G.
+
+ +
+
+++
+
70
Do.
.. A.N. c/o p. ...
-
Positive ?
-
Positive
strong.
-
-
-
-
71
Do.
... C.P. c/o T.S. ..
-
Positive
mode-
rate.
-
Positive
mode-
rate.
-
-
+
+
+++
72
Do.
... C.V.R.M.V.C. c/o
-
Positive
strong.
-
Positive
strong.
T.S.
-
-
-
-
73
Do.
... K.V.K. G.O.H.
+ + +
Negative.
-
Positive
mode-
rate.
*
-
+
+++
74
Do.
.. C. M.H.
...
-
Positive
weak.
-
Do.
-
++
-
+++
+++
75
Do.
... V. M.H.
-
Positive
strong.
-
Positive
strong.
Secondary optic atrophy.
-
-
-
-
-
76
Do.
... S. M.H.
...
-
Do.
-
Do.
Syphilis two years ago.
-
-
-
-
-
-
77
Do.
.. Mr. S.D. G.H.
-
Do.
-
Do.
-
-
-
-
-
-
78
Do.
... E.
...
...
+ +
Negative
-
Do.
Syphilis and gonorrhœa twenty years ago,
*
-
-
-
79
Do.
.. P.G. M.H. ..
- Positive
strong.
-
Do.
-
-
-
-
-
-
80
Do. ...
S. M.H....
-
Do.
-
Do.
-
-
-
-
-
The conclusions which I have arrived at are as follows :
—
(1) The Noguchi's modification is also deficient in the specific body whatever its nature may be, which
is present in the syphilitic liver extract used as antigen in the original Wassermann test.
(2) The mixed method used in the laboratory is therefore superior to it, in that it detects the
syphilitic poison in many long-standing cases such as parasyphilitic ones and ophthalmic cases in which
only a vague history of syphilis dating back for ten years or more can be elicited.
(3) In 14 cases (marked with a single asterisk in the above table) out of 80, the mixed method showed
a positive reaction while Noguchi was negative. There was one case (marked with double asterisks) in
which the Noguchi test was positive and the mixed method failed to give a reaction but this was subse-
quently proved on clinical examination to be non-syphilitic
(4) A certain amount of trouble may also be felt in getting sufficient blood from the staff of a civil
laboratory every time the Noguchi's test is conducted.
Government
of Madras
LOCAL & MUNICIPAL DEPARTMENT (LOCAL).
G.O. No. 361 L., 7th March 1917.
Report.
The — on the working of the Micro-Biological Section of the King Institute, Guindy, for
the year 1916, recorded.
READ—the following paper:—
Letter—from Major W. A. JUSTICE, M.B., C.M., D.P.H., I.M.S., Sanitary Commis
-sioner for Madras.
To—the Secretary to Government, Local and Municipal Department.
Dated—Madras, the 27th February 1917.
No.—D. 529/S.
I have the honour to forward an advance copy of the report on the working
of the Micro-Biological Section of the King Institute, Guindy, for the year 1916.
Printed copies will follow.
2. The experimental filters have been productive of very useful information
and a continuation of these experiments is desirable. Unfortunately these experi
- m e n t s , t h e c l e a n i n g u p a n d p r e p a r a t i o n f o r a n e w e x p e r i m e n t a l l t o g e t h e r , t a k e a
considerable time and it is not possible to complete at most more than three or
four experiments in a year with the sand filters. I am addressing Government
separately for funds and for permission to continue this useful work for some
time longer.
During the time I did locum tenens for the Director, I had ample opportunity
of seeing the good work which the Assistant Directors are daily turning out at
the Institute. Their efficiency reflects great credit on the Director.
Order—No.361 L., dated 7th March 1917.
Recorded.
(True Extract.)
R. A. GRAHAM,
Acting Secretary to Government.
To the Sanitary Commissioner.
„ Surgeon-General.
„ Sanitary Engineer.
„ Local and Municipal Department (Medical Section).
„ Assistant Quartermaster-General, 9th (Secunderabad) Division (with C.L.).
AGENTS FOR THE SALE OF MADRAS GOBVERNMENT
PUBLICATIONS. IN INDIA.
A. C. BARRAUD & Co. (Late A.J. COMBRIDGE & Co.), Madras.
R. CAMBRAY & Co., Calcutta.
E.M. GOPALAKRISHNA KONE, Pudumantapam, Madura.
HIGGINBOTHAMS (Ltd.), Mount Road, Madras.
V. KALYANARAMA IYER & Co., Esplanade, Madras.
G. C. LOGANADHAM BROTHERS, Madras.
S. MURTHY & Co., Madras.
G.A. NATESAN & Co., Madras.
The Superintendent, NAZAIR KANUN HIND PRESS, ALLAHABAD.
P. R. RAMA IYAR & Co., Madras.
D. B. TARAPOREVALA SONS & Co., Bombay.
THACKER & Co. (Ltd.), Bombay.
THACKER, SPINK & Co., 3, Esplanade East, Calcutta.
S. VAS & Co., Madras.
S.P.C.K. PRESS, Vepery, Madras.
IN THE UNITED KINGDOM.
B. H. BLACKWELL, 50 and 51, Broad Street, Oxford.
CONSTABLE & Co., 10, Orange Street, Leicester Square, London, W.C.
DEIGHTON, BELL & Co. (Ltd.), 1, Adelphi Terrace, London, W.C.
T. FISHER UNWIN (Ltd.), 1, Adelphi Terrace, London, W.C.
GRINDLAY & Co., 54, Parliament Street, London, S.W.
KEGAN PAUL, TRENCH, TRUBNER & Co. (Lt d. ), 68-74, Cart er Lane, London, E. C. , and 25, Museum St reet , London, W. C.
HENRY S. KING & Co., 65, Cornhill, London, E.C.
P. S. KING & SON, 2 and 4, Great Smith Street, Westminster, London, S.W.
LAZAC & Co., 46, Great Russell Street, London, W.C.
B. QUARITCH, 11, Grafton Street, New Bond Street, London, W.
W. THACKER & Co., 2, Creed Lane, London, E.C.
OLIVER AND BOYD, Tweeddale Court, Edinburgh.
E. PONSONDY (Ltd.), 116, Grafton Street, Dublin.
ON THE CONTINENT.
ERNEST LEROUX, 28, Rue Bonaparte, Paris.
MARTINUS NIJHOFF, The Hague, Holland.
REPORT
ON THE
WORKING OF THE MICRO-BIOLOGICAL SECTION
OF THE INSTITUTE, G
U I N D Y .
FOR THE YEAR 1917.
( WITH APPENDIX)
MADRAS:
PRINTED BY THE SUPERINTENDENT, GOVERNMENT PRESS.
1918.
For official use only.
REPORT
ON THE
WORKING OF THE MICRO-BIOLOGICAL SE
CTION OF THE KING INSTITUTE, GUINDY,
FOR THE YEAR 1917.
(WITH APPENDIX)
MADRAS:
PRINTED BY THE SUPERINTENDENT, GOVERNMENT PRESS.
1918.
TABLE OF CONTENTS.
PAGE
Report on the working of the Micro-Biological Section by Dr. F. Maitland Gibson, M.B.,
B.sc., Director
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5
APPENDIX.—Notes on Vaccine Therapy by Civil Assistant Surgeon M.Kesava Pai, M.D.
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13