12
A number of cases of sinuses resulting from glandular caseation and suppuration are also
included here and the poor response to vaccine treatment in some of these cases is evidently due
to the unhealthy nature of the tissue in which the sinuses were situated.
Case 18.—Fracture of the astragalus as a result of a fall from the horse. Astragalectomy
was performed but the sinuses left for drainage somehow became infected with B. coli and the
temperature rose as a consequence. This temperature was brought down to normal within five
days of the administration of the first dose of autogenous coli vaccine and though the sinus took
over a month and a half to heal, the favourable effect of the vaccine on the septic temperature
seemed to indicate that there was a definite coli infection in this case.
TABLE VI.
S e r i a l n u m b e r .
Case
number.
Medical officer.
Disease.
Vaccine made.
Result.
1
2
Second
Surgeon,
General
Hospital, Madras.
Compound fracture of
femur osteomyelitis
Streptococcus brevis
Slight improvement.
2
3
Do.
do.
Suppurating glands in
axilla.
Staphylococcus aureus. No effect.
3
6
D .
do.
Suppurating axillary
glands.
Streptococcus brevis.
Cured.
4
1 1
Do.
do.
Inoperable cancer of
breast.
Streptococcus
. . No effect.
5
14
Do.
do.
Suppurating axillary
glands.
Staphylococcus aureus. Not used.
6
18
Third
Surgeon,
General
Hospital, Madras.
Septic
wound
of
ankle.
B Coli
..
.. Cured but mostly due
to local treatment.
7
35
District Medical and Sanitary
Officer, Madura.
Sinus of groin
.. Streptococcus
.. Not used.
8
38
Do.
do.
....
Staphylococcus albus,
Not known.
9
16
Third
Surgeon,
General
Hospital, Madras.
Septic Sinus-glands of
neck.
Streptococcus
.. Not used.
10
56
Do.
do.
Septic wound of face. B Pyocyaneus
.. Not given a fair
trial.
11
6 9
Surgeon,
First
District,
Royapuram.
Sinus of abdomen
.. Staphylococcus aureus. Cured, but as a result
of local antiseptic
treatment—only one
dose of vaccine was
given.
12
70
Dr.
F.
Clarence
Smith,
Madras
Septic wound of leg .. Streptococcus
.. Not known.
13
82
Third
Surgeon,
General
Hospital, Madras.
Septic wound of knee
joint.
Streptococcus brevis.
No result.
14
87
Second
Surgeon,
General
Hospital, Madras.
Syphilitic ulcers of
leg.
'Streptococcus
.. No effect
15
9 0
Do.
do.
Do.
Streptococcus brevis.
Do.
16
106
District Medical and Sanitary
Officer,Madura.
Sinus of groin
.. Staphylococcus
..
Do.
17
115
Third
Surgeon,
General
Hospital, Madras.
Pelvic cellulitis
.. Staphylococcus aureus. Not given a fair trial.
18
152
Medical Officer,
Municipal
Hospital, Trichinopoly.
Sinus in groin
.. Streptococcus
.. Doubtful.
19
164
Third
Surgeon,
General
Hospital, Madras.
Bullet
wound
of
thigh
Do.
Slight improvement.
20
181
Second
Surgeon,
General
Hospital, M adras.
Erysipelas of leg
..
Do.
.. No effect.
21
199
Fir st
Surgeon,
General
Hospital, Madras.
Empyema
..
.. B. Pyocyaneus
.. Not used.
22
229
Third
Surgeon,
General
Hospital, Madras.
Fracture of patella ..
Do.
.. Cured.
Abscesses.— The staphylococcus aureus was the causative organism in the majority of cases.
In a case of mammary abscess and one of ovarian abscess the streptococcus was the preponderant
organism. It is very likely that in cases 61 and 116, the coccobacillus and the B. Pyocyaneous
were extraneous organisms which invaded the sinuses subsequent to the evacuation of pus from
the abscess cavities, keeping up an irritation and preventing their healthy closure by granula-
tion.
Case 128.—Is of special interest as it proves the efficacy of bacterial vaccines in a practically
pyæmic infection with the staphylococcus. It was a case of multiple abscesses in a baby five
months' old. Besides a number of abscesses which had formed and burst before admission into
hospital, the baby developed1 3 a b s c e s s e s m o r e w i t h i n t e n d a y s o f a d m i s s i o n , w h e n a d o s e o f t w o
million autogenous staphylococcus vaccine was administered. No further abscesses formed and
the child discharged completely well after three more injections of 3, 5 and 7.5 million
staphylococci.