17
Cases 37 and 38 were attempts made to treat inflammatory conditions of the cornea
and conjunctiva with vaccines. In case 37 there was considerable chemosis and infiltration
of the cornea along with a nasal discharge from which B. septus was isolated. Treatment
with the autogenous vaccine did no good whatsoever. Case 38 was one of granular ophthalmia
and pannus with blepharitis of eight years' duration. There was a concomitant nasal catarrh
and cultivations were made from the latter. The autogenous staphylococcus aureus vaccine
was administered in doses ranging from 25 to 200 million. Considerable improvement
resulted but it was not possible to say if this was due entirely to the vaccine treatment.
Case 51 is an interesting case of chronic nasal ulceration of four months' duration in a
medical student of the Rayapuram school. The complaint began as a nasal catarrh to which
the Patient was subject from boyhood. The present trouble began with an acute cold on the
subsidence of which an ulcer was noticed on the margin of the right ala nasi. This spread
slowly upwards causing an excoriated appearance of the whole nasal mucous membrane. A
month later the same ulceration occurred on the left side. There was chronic purulent dis
-charge and occasional bleeding from the ulcers. Streptococcus and staphylococcus aureus
were isolated and a combined vaccine made and injected. The discharge gradually lessened
and the ulcers healed by the time 6 doses up to a maximum of 50 million streptococci were
given.
Case 56 was one of chronic pharyngeal catarrh of many years' duration complicated
with follicular tonsilitis and Eustachian catarrh. There were very frequent exacerbations
of the catarrh wherein the patient used to feel the usual malaise and hardness of hearing due
to blocking of the Eustachian canal. Cultivations from the throat gave a mixed growth of
pneumococcus and B. influenzæ. A combined vaccine was made and injected in doses rising
up to 1,000 million of each organism. In about eight months there was considerable im
-provement in the catarrhal condition and the attacks of '
cold in the head' which were very
frequent had almost stopped. The patient has been advised to take an injection every month
for some time longer.
Asthma, chronic bronchitis and lung affections .—Autogenous vaccines were made for 31 cases.
Of these in 9 cases, the vaccine was either not used or not reported upon. Of the remaining
22 cases, 3 are reported as cured, 3 as much improved, 9 as relieved, in 7 there was no effect at
all. The pneumococcus, M. catarrhalis, and B. influenzæ were the usual organisms isolated
either singly or in combination. In the majority of local cases, cultivations were made from
the sputum collected fresh in the laboratory. In 18 cases cultivations were sent by post from
up-country stations. Such cultivations, when they reached the laboratory, showed a good
growth of the respective organisms and were ready for isolation and sub-cultivation for the
preparation of the vaccine, which could thus be supplied almost as speedily as an autogenous
vaccine for a local case.
TABLE VIII.
Asthma, bronchitis and lung affections.
Serial
num-
ber.
Case
num-
ber.
Medical Officer.
Disease.
Vaccine made.
Result.
1
2 The Officer Commanding Section
Hospital, St. Thomas' Mount.
Bronchitis . . .
Streptococcus and M.
Catarrhalis.
Much im-
proved.
2
3 Dr. S. P. Sarma, Tiruvalur . . .
Chronic bronchitis
and asthma.
Pneumococcus and
M. Catarrhalis.
Asthma re-
lieved.
3
4 Rao Sahib K. Madhava Menon, Cochin. Asthma . . .
Pneumococcus and
streptococcus.
Much better.
4
8 Dr. S. P. Sarma, Tiruvalur . . .
Do. . . .
Pneumococcus . . .
No effect.
5
12 The First Physician, General Hospital,
Madras.
Do. . . .
Pneumococcus and
B. influenzæ.
Doubtful.
6
13 Lieut.-Col. G. G. Giffard, C.S.I., I.M.S.,
Madras.
Bronchitis . . .
Do.
Not known.
7
20 Dr. S. P. Sarma, Tiruvalur . . .
Asthma. . .
Pneumococcus . . .
Not used.
8
22 Rao Sahib K. Madhava Menon, Cochin.
Do. . . .
Do. . . .
Cured.
9
39 Lieut.-Col. Leventon, I.M.S., Assam . . . Bronchitis . . .
Do. . . .
Not known.
10
40 The Superintendent, Royapetta Hos-
pital, Madras.
Asthma . . .
Pneumococcus and
B. influenzæ.
Do.
11
48 Rao Sahib K. Madhava Menon, Cochin.
Do. . . .
B. influenzæ and M.
Paratetragenus.
No effect.
12
54 The First Physician, General Hospital,
Madras.
Do. . . .
Pneumococcus . . .
Not used.
13
58 Rao Sahib K. Madhava Menon, Cochin.
Do. . . .
Do. . . .
Cured.
14
67 The Superintendent, Government
Lunatic Asylum, Madras.
Do. . . .
Do. . . .
Improved.
15
68 The Superintendent, Government
Maternity Hospital, Madras.
Do. . . .
Do. . . .
Not used.
16
72 Sub-Assistant Surgeon Srinivasa
Ayyangar, Coimbatore.
Do. . . .
Do. . . .
Improved.
4