41
TABLE XXX.
MULE II. Showing the daily mean of Corpuscles in the massed paroxysms and intermissions.
Periods.
Health
Latent period
Paroxysms
Intermissions
Whole period
Days.
28
8
39
14
89
Red corpus-
cles in
1 c. mm.
6,480,000
6,601,250
4,223,333
4,352,857
5,167,415
White
corpuscles
in
1 c. mm.
10,964
8,175
12,251
14,285
11,799
Coarsely
granular
oxyphile
cess in
1 c. mm.
2,621
1,725
1,036
1,485
1,667
Ratio
white to red
corpuscles.
1:591
1:807
1:345
1:304
1:437
Ratio
coarsely
granular
cells to white
corpuscles.
1: 4.18
1: 4.25
1:11.82
1: 9.62
1: 7.08
Ratio
coarsely
granular
cells to red
corpuscles.
1 : 2.472
1 :3,826
1 :4,076
1 :2,931
1:3,099
Number
hæmatozoa
in 1 c. mm.
blood.
...
...
2,476
...
...
Per cent.
hæmo-
globin.
100.00
111.00
67.12
65.32
78.54
TABLE XXXI.
MULE II. Showing the percentage of Corpuscles present in the massed periods, &c.,
taking the number in the health period as 100.
Periods.
Health
Latent period
Paroxysms
Intermissions
Whole period
...
...
...
...
...
...
...
...
...
...
Red corpuscles
%
100.00
101.87
65.17
67.17
79.74
White corpuscles
%
100.00
74.56
111.73
130.38
107.61
Coarsely
granular
corpuscles
%
100.00
65.81
39.52
56.65
63.60
Remarks comparing the results obtained in the cases of Mules I and II.
Two mules, No. I weighing 698.5 lbs. and No. II 705.6 lbs., appeared in perfect health
and condition; No. II was fed on lucerne and hay, the other with corn in addition. Dur-
ing the period of (28 days) health, both animals walked 3 miles daily after inoculation; the
mule receiving corn was only able to walk an average of 1.6 miles, during the first 62 days
out of 114 under experiment, whilst Mule No. II, not receiving corn, was able to walk an
average of 3.78 miles daily, until death from chloroform 89 days later.
In both instances, the quantity of urine excreted during the different periods of health
and disease was somewhat similar, but there was a marked difference in the amount of
urea. Mule I excreted in health an average of 91.24 grammes daily, which was four times
the amount excreted by the other mule without corn. In the case of the former animal,
the amount of urea in health was 91.24 grammes ; this was reduced in the latent period
by 17.1%. It was further reduced in the paroxysms by 44.0% and in the intermissions
by 45.40 %, owing to the animal refusing his corn and part of his fodder at an early
date of the disease during paroxysm I. Had the mule continued to eat his corn ration
throughout, the amount of urea in the paroxysms would probably have exceeded that of
health, as observed in previous cases. In the mule not receiving corn, the amount of urea
in health was only 23.54 grammes, which increased 22 % in the latent period, and during
the paroxysms and intermissions by 121 and 179 % respectively. The ratios for the different
periods in each case, health being taken as 1, were :—
Animals
Mule I (corn) ...
Mule II (grass) ...
Health.
1
1
Latent Period.
0.88
1.22
Paroxysms.
0.56
2.21
Intermissions.
0.54
2.79
With regard to the hippuric acid, in Mule I, the excretion continued until the end of
the fourth paroxysm, or 54.38 % of the total length of the case. The quantity was only
small, but was highest during the latent period. From Table XIX it will be observed, that
the excretion of hippuric acid ceased when exercise was discontinued, but it is doubtful
whether this was the actual cause, as when exercise was recommenced at a later period no
hippuric acid appeared in the urine.
In Mule II the amount of hippuric acid in health and the latent period was much
higher than in Mule I, but it fell during paroxysm I, and disappeared in paroxysm II,
although exercise was continued throughout the case. It is a point of interest that, as in
B 563—11