27
of large numbers of the Filaria papillosa in the blood, in addition to varying numbers of the
Trypanosoma Evansi. For three days previous to the death of No. 13 the temperature
ranged between 95° and 105° F., a variation of ten degrees, but at the autopsy few pathologi-
cal changes were noted, and those of a slight character.
No. 152 Bullock, which presented quite as an advanced condition of Surra as the one
that succumbed, very gradually recovered. At a later date, September 1896, had put on flesh
and presented a good condition, although for some time it was quite off its feed, and only ate
when tempted by lucerne grass placed in its mouth. The temperature in this case ranged
between 99° and 107° F., and for a considerable period after the special Surra symptoms had
passed the morning remissions and evening exacerbations of temperature were most marked.
This fever of an intermittent type was not due to Surra or Filariasis only, alone or combined,
but was a special form of disease of malarial origin. For at Karnal malarial fever in bovines
and equines appears alone, as well as complicating other disorders.
Bull V (Hill animal), aged two years, was kept under observation from the 27th Novem-
ber, 1896, until 15th February, 1897. On the 16th February it was inoculated on the ear, a
minute incision being made and a trace of blood containing a few Hæmatozoa, taken from
Buffalo I, was placed between the edges of the wound. The latent period occupied six days.
The Hæmatozoon was present in the blood from the 1st to the 3rd of March inclusive. After
an interval of three days it was again present in large numbers for four days, March 7th to
the 10th; after a second interval of five days it re-appeared for one day on the 16th March.
During a further period of 147 days, accompanied by daily microscopical examinations of the
blood, no organisms were observed. During the period of observation lasting 89 days
the temperature varied between 39.3° and 36°C., and between 38.9° and 37.1°C. during the
latent period of the disease. On the appearance of the Hæmatozoon the temperature
became rapidly elevated and attained a maximum of 42.5°C. (108.5°F.) on the third
evening, and then gradually fell until the morning of the 7th day of the disease; when
it registered 37.5°C. It again rose to 40.5°C. on the 9th, and remained at that point
until the evening of the 10th day, when it fell to 37.4°C. The pyrexia since March 11th has
been characterized by morning remissions and evening exacerbations, especially on the 42nd,
49th, 58th, 102nd, 116th, 125th days of the disease. During the months of May, June,
and July, this animal became greatly emaciated, but during August commenced to put on flesh
and fill out again.
August 31st, 1897.—This animal is now in fair condition ; the hæmatozoon has been
absent from the blood since March 15th, 1897, a period of intermission lasting 168 days up
to date.
TABLE IV.
Showing the Paroxysms and Intermissions registered during the case, together with the variations
in numbers of Hæmatozoa recorded in the paroxysms, and temperatures during each period.
PERIOD.
Observation.
Latent Period .
Paroxysm I .
Intermission I .
No.
of
days.
89
6
3
3
Hæmatozoa
varied from
...
...
Few—swarming
...
TEMPERATURE.
Maxi-
mum
°C.
39.3
38.9
41.5
40.0
Mini-
mum.
°C.
36.0
37.1
37.4
37.5
PERIOD.
Paroxysm II .
Intermission II
Paroxysm III
Intermission
III
No.
of
days.
4
5
1
147
Hæmatozoa
varied from
Few—swarming
...
Few—few
...
TEMPERATURE.
Maxi¬
mum.
°C.
40.5
38.6
38.6
41.0
Mini¬
mum.
°C.
37.5
37.0
37.5
37.1
Buffalo No. I (Genus-Bubalus), aged 2½ years, was kept under observation for a period
of 44 days previous to inoculation (16th November 1897) on the muffle with a trace of blood
containing swarms of Surra Hæmatozoa. The material was taken from a young cat, which
had previously been inoculated from a Surra horse in the plains. No change was observed at
the seat of the small incision, between the edges of which the soiled blood was placed. The
latent period occupied five days. The time which elapsed between the first appearance of the
Hæmatozoon and death, viz., 120 days, was made up of 12 paroxysms lasting 39, and 11 inter-
missions lasting 81 days. During the course of the disease the animal lost flesh, and towards
the last became somewhat emaciated, notwithstanding the voracious appetite which was main¬
tained until two days before death.
E 2