19
carcasses in enormous numbers in its wake. Now, instead of thousands of
animals succumbing as the result, in some instances, of only one unchecked
outbreak, it is becoming difficult in those provinces which are in the van of
serum therapy to observe any large outbreaks at all. This result is easily
understood when we consider that, in the above-mentioned provinces, immedi-
ately an outbreak is discovered by those in charge, the whole of the affected
and contact animals are injected with serum or a cordon of protected cattle
is formed round the primary focus of the disease and its further progress
stopped.
61. Anthrax.—-During the year 1905-1906, 224,310 c. c. of Anthrax
protective serum which is equivalent to 44,862 doses, were prepared, as against
27,471 doses during the previous year. The total issue, as per Appendix II,
was 26,712 doses. The demand for this serum was greater by 4,321 doses
than that of the last year and by 18,647 doses than of the year before last.
62. The following abstracts from the returns of the Superintendents,
Civil Veterinary Department, will show the results of injections carried out
with Anthrax protective serum in their respective provinces:—
63. United Provinces.—
Injections with Anthrax protective serum.
1
Hamirpur
.
Faizabad
Muzaffarnagar
Gonda .
.
Bijnor
.
.
Azamgarh
.
2
April 1905
June, Angust and Sep-
tember 1905.
September 1905
.
October and December
1905.
November 1905
Ditto
TOTAL.
.
Number of outbreaks in
which inoculation was
undertaken.
3
3
40
1
2
10
1
57
Number of animals died
uninocalated in course
of outbreak.
Equities.
4
...
...
...
...
...
...
...
Bovines.
5
...
58
9
5
15
24
111
Others.
6
...
...
...
...
...
...
...
Number of animals
inoculated.
Equines.
7
...
...
...
...
...
...
...
Bovines.
8
500
579
385
406
418
105
2,393
Others.
9
...
...
...
...
...
...
...
Number of inoculated
animals which died
of the disease.
Equines.
10
...
...
...
...
...
...
...
Bovines.
11
...
...
...
...
...
...
Others.
12
...
...
...
...
...
...
...
REMARKS.
13
Death-rate nil.
It will be noticed that, out of 2,393 head of cattle injected with Anthrax
protective serum in 57 outbreaks of the disease in the United Provinces of
Agra and Oudh, no death was reported after injection.
64. Results of the use of anti-Anthrax serum in an outbreak of the dis-
ease in human beings.—A severe outbreak of Anthrax occurred amongst the
prisoners working in wool at the Central Jail in Bareilly in December 1905,
and, on my suggestion, the Medical Superintendent undertook to utilize the
anti-Anthrax serum, prepared at this Laboratory, to treat those persons already
affected and to grant a passive immunity to those already exposed to the " con-
tagium." Major E. Jennings, I.M.S., has kindly supplied me with the following
details of the outbreak :—
Number of cases
affected.
† Twelve
with
Anthraoæmia,
and one with
malignant pustule.
Number of
deaths before
serum treat-
ment.
3
Number
injected with
anti-Anthrax
serum.
9
Number
recovered.
5
Number
died after
injection.
4*
REMARKS.
* Two cases were not treated with serum until
tetanic spasms had supervened and two which
were progressing most favourably, in spite of
implicit orders to the contrary, feeling better
sat up in bed and fell back dead.
†In addition, 4 doubtful cases, 3 of which
were treated with serum, all recovered.
Note.—In four cases which received serum, but ultimately died, compared with those which did not receive
serum and succumbed, life was considerably prolonged.
C 2