57
TABLE XLI.
Showing the percentages of Red Corpuscles, taken on the mean daily number in the blood
of the Horse and Mule, during different periods of health and disease (Surra).
Periods.
Health
...
...
...
Latent period
...
...
Paroxysms...
...
...
Intermissions
...
...
Whole period
...
...
Length
in
Days
15
7
47
5
74
Horse
No. LXXXIX
%
100.00
109.70
86.01
74.98
87.16
Length
in
Days.
28
11
49
26
114
Mule I.
%
100.00
105.00
61.34
52.35
68.67
Length
in
Days.
28
8
39
14
89
Mule II.
%
100.00
101.87
65.17
67.17
79.74
(ii) After unsuccessful inoculation with the Bandicoot hæmatozoon.—Taking the mean of five
inoculations (donkey), the effect produced 24 hours after inoculation was to increase the number
of red corpuscles 10.48 %, whilst at the end of 72 hours a reduction in their numbers equal
to 11.79 %. had taken place.
(iii) Treatment of Surra Animals with Arsenic.—In horses, after an interval of several
days, from the 9th to 12th day of treatment, a considerable increase in the number of red
corpuscles took place, in some cases approaching 70 to 100 %. This rise was followed by
a fairly gradual decrease, which in a mean of 8 cases was found to commence on the 41st day
of treatment, after 403.4 grains of arsenic had been administered. A secondary increase in the
numbers recorded, occurred just before death in 5 out of 8 cases.
WHITE CORPUSCLES.
(i) When Surra acquired naturally or by inoculation.—A decrease in the number of white
corpuscles took place during the period of incubation, varying from 8 to 25 per cent. During
the paroxysms an increase occurred, which in the mule was enormously added to during the
intermissions. In No. LXXXIX Horse, the length of intermissions compared with the paroxysms
were as 1: 9.4, whereas in the mules they were as 1: 1.9, and 1: 2.8 respectively.
TABLE XLII
Showing the percentages of White Corpuscles, taken on the mean daily number, in the
blood of the Horse and Mule, during different periods of health and disease (Surra).
Periods.
Health
...
...
...
Latent period ... ...
Paroxysms
...
...
Intermissions ... ...
Whole period
...
...
Length
in Days.
15
7
47
5
74
Horse
No. LXXXIX.
%
100.00
91.20
142.89
141.02
134.23
Length
in Days.
28
11
49
26
114
Mule I
%
100.00
89.93
100.69
135.31
108.66
Length
in Days.
28
8
39
14
89
Mule II.
%
100.00
74.56
111.73
130.38
107.61
(ii) After unsuccessful inoculation with the Bandicoot hæmatozoon.—Taking the mean of
five inoculations, the effect produced (in the donkey) 24 hours after, was to increase the white cor-
puscles by 76 %; whilst at the end of 72 hours a reduction of 69 % of the increase had occurred.
(iii) Treatment of Surra with Arsenic.—In the case successfully treated with Arsenic,
the number of white corpuscles rapidly decreased, and never attained during recovery within
75 % of the number present at the commencement of treatment. A similar reduction
was observed to take place in the course of the fatal cases, when the system of the animal
became influenced by the drug. Fluctuations in the number of the white corpuscles, however,
occurred, which did not appear to correspond with any rise or fall in the number of red or the
coarsely granular oxyphile cells. In the majority of cases recorded, shortly before death a
considerable increase in the number of white corpuscles took place, concurrently with the rise in
red.
COARSELY GRANULAR OXYPHILE CELLS (EOSINOPHILE CELLS).
(i) When Surra acquired naturally or by inoculation.—A great diminution in the number
of coarsely granular cells was observed during the latent period, but the greatest decrease in
their numbers was observed during the paroxysms of Surra, in the majority of cases. When
the intermissions were sufficiently prolonged, there was a rapid increase in the number of these
cells, during the absence of the hæmatozoon from the circulation, and the consequent fall in
temperature.
B 563—15