149
Date.
1892.
November
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December
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Day of
Disease.
5 ...
6 ...
7 ...
8 ...
9 ...
10 ...
11 ...
94
95
96
97
98
99
100
Two guinea
12 ...
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
19 ...
20 ...
21 ...
22 ...
23 ...
101
102
103
104
105
106
107
108
109
110
111
112
Temperature °C.
A. M.
38.7
38.7
38.1
38.4
38.4
38.4
38.6
1 P.M.
40.1
38.7
38.4
38.7
39.7
39.5
39.7
5 P. M.
40.6
38.2
38.5
38.7
40.2
40.2
40.5
Pulse.
A. M.
72
72
56
64
64
64
64
P.M.
60
60
64
60
68
68
64
Respiration.
A.M.
20
20
16
20
20
12
12
P. M.
33
16
20
24
16
16
12
Hæmatozoa
in Blood.
Absent.
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Colour.
Trurbid.
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Urine.
Sp. Gr.
1,020
1,022
1,022
1,030
1,030
1,022
1,028
Reaction.
Alkaline.
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Albumen.
1/10
1/12
1/38
1/33
1/32
1/13
1/12
Pigs were each inoculated with 0.3 c. c. of blood taken from this animal.
38.0
38.2
37.1
37.0
37.3
38.7
38.7
38.4
37.7
37.0
37.4
37.0
39.1
38.8
38.6
38.0
39.7
38.8
39.0
39.0
39.3
38.2
38.2
38.0
38.8
39.0
39.2
39.1
39.4
40.1
39.4
39.5
38.7
38.8
38.6
39.3
60
68
64
60
60
68
60
64
60
60
64
64
68
64
68
64
72
64
64
64
72
64
64
76
12
20
12
16
12
12
12
12
12
12
12
16
24
20
28
16
20
16
20
16
20
20
20
24
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Few.
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Numerous-
Absent.
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1,034
1,024
1,026
1,030
1,034
1,018
1,025
1,023
1,020
1,026
1,036
1,020
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1/11
1/32
1/28
1/26
1/30
1/36
1/11
1/15
1/16
1/11
1/9
1/16
The hæmatozoon appeared in the blood of each of the guinea pigs inoculated on the 11th instant.
24 ...
25 ...
26 ...
27 ...
28 ...
29 ...
30 ...
1 ...
2 ...
3 ...
4 ...
5 ...
6 ...
7 ...
8 ...
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
37.6
38.0
39.5
39.8
37.7
36.6
39.0
36.6
39.0
37.6
40.4
40.1
37.7
36.5
35.5
39.1
39.1
39.8
40.2
39.1
37.0
39.1
37.7
39.8
39.3
40.1
40.6
39.6
38.2
37.3
39.3
40.3
40.5
39.8
39.5
39.1
38.1
39.6
40.4
39.5
40.4
39.7
39.1
38.8
38.2
64
64
64
80
56
48
64
52
60
64
88
72
64
52
48
72
72
68
84
68
68
68
64
64
72
96
72
64
64
60
12
20
16
16
12
12
16
16
20
12
16
20
12
12
8
16
34
32
20
16
12
16
24
20
16
28
28
20
12
16
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Few.
Numerous.
Absent,
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Few.
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Very nu-
merous.
Absent.
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1,022
1,028
1,018
1,020
1,024
1,032
1,036
1,032
1,032
1,024
1,024
1,020
1,022
1,028
1,026
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1/10
1/7
1/13
1/9
1/9
⅛
⅛
⅛
1/11
⅛
1/21
1/7
1/12
1/15
1/18
No difference is observable whether the temperature of the animal is 42° C or 35.5° C. as registered this
morning ; its gait is firm and appetite unchanged.
9 ...
10 ...
11 ...
12 ...
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
19 ...
128
129
130
131
132
133
134
135
136
137
138
36.4
37.7
38.7
38.6
37.4
36.2
36.0
37.5
37.6
37.4
38.5
38.1
38.4
40.4
42.0
40.4
39.2
38.6
38.7
38.2
38.5
38.6
38.5
40.1
40.4
41.2
39.6
39.0
39.2
38.6
38.5
38.4
40.3
52
60
64
68
80
56
64
64
72
64
60
64
76
76
108
88
80
84
76
76
76
80
12
12
12
16
12
12
12
16
12
12
16
12
24
16
20
16
16
12
16
16
16
16
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Few.
Swarming
Absent.
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Very nu-
merous.
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1,020
1,046
1,032
1,038
1,045
1,038
1,030
1,022
1,030
1,032
1,028
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1/12
1/12
1/18
1/14
1/18
1/12
1/15
1/22
1/12
1/12
⅛
The animal is now becoming very weak and is losing power over the hind limbs.
20 ...
21 ...
22 ...
23 ...
24 ...
139
140
141
142
143
38.3
38.4
39.0
38.7
35.0
38.6
39.5
39.0
392
39.4
39.7
39.8
39.2
39.2
39.0
72
64
68
88
64
80
88
96
88
88
12
12
12
32
16
16
20
16
20
16
Absent.
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Numerous
„
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1,022
1,028
1,022
1,024
1,020
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1/9
1/15
1/13
1/15
1/16
The animal is very weak, pulse feeble and thready, but the appetite is almost voracious.
25 ... 144 35.4
... ...
80 ... 32 ... Few.
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1,016
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1/12
The animal is still weaker, but is still able to feed. At 10 A.M., the animal fell, and death occurred
at 11-30 A.M.
Note.—Examination of urine. Numerous forms of carbonate of lime crystals and a few oxalates
were present throughout the course of the disease ; Epithelial casts were observed for the first
time on the 18th September, and were followed at a later period by granular casts in varying
numbers.
Hippuric acid and phosphates were examined for throughout the case ; the former was entirely
absent, and the latter was present in traces on four occasions only.
2236—38 ap