NationalLibraryOfScotland/medical-history-of-british-india huggingface dataset:
158
GUINEA PIG.
28th October 1893. Inoculated subcutaneously, at 1.30 P.M. with 0.3 c.c. of blood containing few hæmatozoa, taken
from the Cow No. 1.
Month and Date.
1893.
October
„
„
„
November
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
December
„
„
„
„
„
„
28...
29...
30...
31...
1...
2...
3...
4...
5...
6...
7 ...
8 ...
9...
10...
11...
12...
13...
14 ...
15...
16...
17...
18...
19...
20...
21...
22...
23...
24...
25...
26...
27...
28...
29...
30...
1...
2...
3 ...
4...
5...
6...
7...
Examination of Blood.
Inoculated
... ...
Hæmatozoa absent ...
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do,
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
do. ...
do. ...
do. ...
few ...
numerous ...
very numerous.
absent ...
do. ...
do. ...
few ...
very numerous.
few ...
numerous ...
very numerous.
do. ...
numerous ...
do. ...
few ...
very numerous.
do. ...
do. ...
do. ...
do. ...
swarming ...
do. ...
do. ...
do. ...
do. ...
do. ...
do. ...
very numerous.
few ...
do. ...
do. ...
numerous ...
few ...
numerous ...
very numerous.
do. ...
Temperature °C.
A.M.
...
38.0
37.8
37.9
37.2
38.0
39.2
39.5
38.6
37.8
38.4
38.5
39.8
38.8
38.2
38.6
38.4
38.2
38.4
37.8
38.8
39.0
38.4
38.1
38.4
38.4
38.6
38.3
38.6
38.0
39.2
37.8
38.0
38.2
37.6
38.2
39.0
38.2
37.8
37.6
38.0
P.M.
39.0
39.2
39.4
39.4
38.9
39.3
39.8
39.5
39.8
38.8
38.6
39.0
39.6
38.8
38.6
39.2
39.6
39.2
38.6
39.4
39.2
40.0
39.0
39.4
39.2
39.6
39.2
39.6
39.2
39.5
38.4
38.6
38.9
39.0
38.8
39.2
39.2
38.6
38.4
38.3
37.0
Month and Date.
1893.
December
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
1894.
January
„
„
„
„
„
„
„
„
„
„
„
8...
9...
10...
11...
12...
13....
14...
15...
16...
17...
18...
19...
20...
21...
22...
28...
24...
25...
26...
27...
28...
29...
30...
31...
1..
2..
3..
4..
5..
6..
7..
8..
9..
10..
11..
12..
Examination of Blood.
Hæmatozoa
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
numerous ...
few ...
do. ...
numerous ...
do. ...
few ...
numerous ...
very numerous.
do. ...
do. ...
do. ...
do. ...
few ...
do. ...
do. ...
do. ...
numerous ...
few ...
numerous ...
do.
...
do. ...
do. ...
few. ...
do. ...
Hæmatozoa few ...
Do...
Do...
Do...
Do...
Do...
Do...
Do...
Do...
Do...
Do...
Do...
do. ...
numerous ...
very numerous
swarming ...
very numerous.
do. ...
swarming ...
do. ...
do. ...
do. ...
... ...
Temperature °C.
A.M.
38.2
38.0
38.4
38.0
38.2
37.8
38.0
38.6
38.4
38.2
38.0
38.2
38.8
38.6
38.8
38.8
38.6
38.8
38.6
39.0
38.8
38.6
39.0
39.2
39.4
39.0
38.3
38.8
38.6
39.0
39.0
39.2
38.5
38.4
38.4
37.7
P.M.
38.8
38.4
38.2
39.0
39.0
38.6
38.4
39.2
39.2
38.4
38.4
39.0
39.2
39.6
39.8
40.0
39.6
39.8
39.6
39.8
39.4
39.6
39.8
39.4
39.4
39.6
39.8
40.4
39.6
40.2
40.0
39.4
39.6
39.4
39.0
36.9
Death at 7 P.M.
165
EXPERIMENT No. I.
RABBIT INOCULATED WITH BLOOD DERIVED FROM THE RAT PREVIOUSLY PASSED THROUGH THE HORSE.
21st, July 1892. 5-20 P.M. —Inoculated the animal subcutaneously in the right inguinal region with .75 c.c. of blood
containing numerous hæmatozoa drawn from the heart of Horse No. LXII, fifteen minutes after death.
This horse was inoculated with Rat's (Mus decumanus) blood. Temp. P.M. 39.8 °C.
22nd.—Temp. A.M. 39.4 °C. No hæmatozoa in the blood. Temp. P.M. 40.0 °C.
23rd.—Temp. A.M. 39.5 °C. No hæmatozoa in the blood. Temp. P.M. 40.1 °C.
24th.—Temp. A.M. 39.8 °C. No hæmatozoa in the blood. Temp, P.M. 40.2 °C.
25th.—The blood on microscopic examination presents a healthy colour, the red corpuscles do not form healthy
rouleaux; but the white corpuscles are not increased in number. Temp. A.M. 39.3 °C There are no
hæmatozoa. Temp. P.M. 39.8 °C
26th.—Temp. A.M. 39.6 °C. There is no swelling or œdema at the seat of inoculation, nor has there been any.
There are no hæmatozoa in the blood. Temp. 40.0 °C.
27th.—Temp. A.M. 39.3 °C. The animal appears bright and healthy, appetite good. There are no hæmatozoa in
the blood. Temp. P.M. 40.0 °C.
28th.—Temp. A.M. 39.6°C. Condition unchanged. The tunicæ vaginales testes do not contain any fluid. There are
no hæmatozoa in the blood.. Temp. P.M. 40. 0 °C.
29th.—Temp. A.M. 39.4ºC. Hæmatozoa absent from the blood. Temp. P.M. 40.0 °C.
30th.—Temp. A.M. 40.0 °C. There are no hæmatozoa in the blood. Temp. P.M. 39.3°C.
31st.—The animal does not appear so well this morning, but there is no swelling, &c., at the seat of inoculation.
Temp. A.M. 38.6ºC. There are no hæmatozoa in the blood. Temp. P.M. 38.5°C..
1st August.—Death occurred in the early morning.
B 2236—42 ap
B.
RAT SURRA.
APPENDIX VII.
PROLONGED GASTRIC INGESTION OF RAT'S EXCREMENT MIXED WITH CORN.
IN POONA,
IN BOMBAY,
„
RESULT
„
„
NEGATIVE,
POSITIVE,
NEGATIVE,
HORSE
„
„
No.
„
„
LXXV.
XCI.
LXXXIX
CROSSED.
174
Month and Date.
1893.
September 5
„ 6
...
„ 7
...
„ 8
...
„ 9
...
„ 10
...
„ 11
...
„ 12
...
„ 13
...
„ 14
...
„ 15
...
„ 16
...
„ 17
...
„ 18
...
„ 19
...
„ 20
...
„ 21 ...
„
22
...
„ 23
...
„ 24
...
„ 25
...
„
26
...
Temperature °C.
A.M.
37.7
37.7
37.7
37.8
37.7
37.6
37.8
37.8
37.8
37.7
37.8
37.8
37.8
37.7
37.6
37.8
37.5
37.6
37.6
37.6
37.7
37.8
1 P.M.
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
Pulse.
A.M.
36
36
36
34
36
34
34
36
36
36
31
34
36
36
34
36
36
38
40
38
38
40
P.M.
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
Respiration.
A.M.
16
15
16
16
16
15
16
15
16
15
15
16
16
17
16
15
17
17
16
17
17
17
P.M.
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
Temperature in
Shade °F.
Maximum..
85.5
83.0
81.0
84.5
83.5
84.5
86.3
86.5
85.5
84.0
85.5
84.0
83.5
84.5
83.5
84.5
85.0
84.5
82.5
85.0
84.0
84.5
Minimum.
75.0
78.0
74.5
77.5
77.0
77.5
76.5
78.5
77.5
76.0
76.0
75.5
75.0
74.0
77.0
76.0
75.5
74.0
75.5
74.5
74.5
76.0
Humidity.
91
87
91
85
80
78
80
81
83
87
87
84
87
84
91
82
89
88
89
93
93
91
Condition
of Blood.
Healthy.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
REMARKS.
Date.
1893.
September 27.
„
28.
„
29.
„
30.
October
1...
„
2...
„ 3...
„
4...
„
5...
„
6...
„
7...
„
8...
„
9...
„
10...
„
11...
Temperature °C.
A.M.
37.6
38.8
39.8
37.7
38.0
39.1
38.1
37.3
37.7
37.7
37.4
37.2
36.8
37.1
37.4
1 P.M.
37.9
40.2
40.1
38.1
39.0
40.3
38.4
37.5
37.8
37.3
37.4
37.3
37.8
37.4
37.7
5 P.M.
38.2
40.3
38.4
37.8
38.6
39.1
38.2
37.3
37.7
37.7
37.3
37.0
37.8
37.6
37.6
Pulse.
A.M.
36
44
48
36
32
44
36
32
36
40
36
32
32
36
44
P.M.
36
44
44
32
36
44
48
36
40
36
36
36
32
36
36
Respiration.
A.M.
32
20
16
24
12
20
16
20
24
32
16
20
16
28
24
P.M.
16
32
36
24
32
24
12
24
28
26
24
20
16
40
16
Day of
Disease.
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
Hæmatozoa
in the
Blood.
Absent
Very nu-
merous.
Numer-
ous.
„ ...
Very nu-
merous
Few ...
Absent;
„ ...
„
„
„
„
„ ...
„
„
REMARKS.
27th.—Animal arrived from Bombay
in good condition, and apparently in
perfect health.
28th.—An urticarial eruption is present
over the whole body, but specially
involving the abdomen and thighs.
There is also a small swelling over
the ensiform cartilage. Right con-
junctival membrane tinged yellow
and slightly petechiated. 5 P.M.
eruption beneath the abdomen is now
more marked.
29th.—Animal dull, eruption decreas-
ed on the thighs, but increased under
the abdomen. 5 P.M. eruption again
more marked.
30th.—Eruption almost disappeared,
except from the shoulders. Conjune-
tivæ petechiated and visible mucous
membranes congested.
Appetite
normal.
1st.—Eruption still observable beneath
the chest and abdomen.
2nd.—No apparent change in con-
dition, but both conjunctival mem-
branes tinged yellow.
4th.—Faint trace of eruption still pre-
sent on the thighs.
6th. The eruption has entirely dis-
appeared, and the animal is slightly
falling off in condition.
9th.—Conjunctivæ and visible mucous
membranes clear.
B.
RAT SURRA
APPENDIX VIII.
SUBCUTANEOUS INOCULATION WITH THE BLOOD OF DIFFERENT ANIMALS
WHICH HAD BEEN PRIMARILY INOCULATED FROM HORSE No. XCI.
(RAT EXCREMENT INGESTION.)
HORSE No. XCV.—CAT No. III.—GUINEA PIG No. XXIII.
181
APPENDIX VIII.
SUBCUTANEOUS INOCULATION WITH BLOOD OF DIFFERENT ANIMALS WHICH HAD
BEEN PRIMARILY INOCULATED FROM HORSE No. XCI (RAT EXCREMENT.)
HORSE No. XCV.
A brown gelding, in fair health and condition.
Date.
1893.
October
„
„
„
„
„
„
„
„
„
„
„
„
„
5 ...
6 ...
7 ...
8 ...
9 ...
10 ...
11 ...
12 ...
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
Temperature °C.
A.M.
...
36.4
36.4
36.6
36.8
36.4
37.2
37.1
37.1
37.6
39.6
39.6
38.4
38.4
NOON.
...
...
...
...
...
37.0
37.4
36.4
37.3
39.3
40.2
39.7
38.8
39.6
P.M.
37.0
37.2
37.3
37.6
37.0
36.8
37.0
36.7
37.5
39.0
39.6
40.0
39.6
...
Pulse.
A.M.
...
36
36
56
32
32
36
28
40
28
36
48
52
36
P.M.
56
36
40
36
36
36
40
20
40
40
40
60
56
...
Respiration.
A.M.
...
40
16
32
32
16
32
32
48
28
24
28
20
40
P.M.
32
36
36
40
36
40
20
40
28
32
36
32
32
...
Hæmatozoa.
in
Blood.
Healthy.
„
„
„
Absent .
Absent .
„
„
„
Few ...
Swarm
ing.
„
„
Very nu
merous.
Day
of
Disease.
...
...
...
...
...
...
...
...
1
2
3
4
5
REMARKS.
5 P.M.—Inoculated over the left scapular
region with 0.7 c. c. of blood containing
very numerous hæmatozoa taken from the
heart of a Guinea Pig immediately after
death, which was originally inoculated
from Horse No. XCI.
There is a slightly raised swelling at the
seat of inoculation, measuring 2"×1⅓"
which is tender on manipulation, Con
junctivæ injected.
Conjunctivæ clear ; the swelling is in
creased in size.
Animal dull, the swelling is less tense, and
there is no tenderness on manipulation.
Conjunctivæ yellow, the right presents an
extravasation. The swelling has decreased
in size, and there is no tenderness.
The swelling is further decreased. Ap
petite continues good, and the fæces are
normal in character.
The left conjunctivæ presents numerous
petechiæ, also the mucous membranes of
the nose. Slight discharge from nostrils.
The animal fell at 2-0 P.M. and Chloro
form was administered.
CAT No. III.
A tabby, full grown, and apparently in good health and condition.
June 30th, 1894.—Inoculated with 0.15 c.c. of blood, containing very numerous hæmatozoa, taken from a Guinea
Pig, immediately after death.
Date.
1894.
June
29 ...
„ 30
...
July
1
...
„ 2
...
„ 3
...
„ 4
...
„ 5
...
„ 6
...
„ 7
...
„ 8
...
Temperature °C.
A.M.
39.0
38.5
38.6
38.2
39.4
39.2
40.0
39.2
39.6
39.4
P.M.
39.6
39.0
38.4
38.8
38.8
39.8
39.0
40.0
40.2
39.1
Condition of Blood.
Healthy.
Inoculated.
Hæmatozoa
„
„
„
„
„
„
„
Absent.
„
„
„
„
„
Few.
„
Date.
July
„
„
„
„
„
„
„
„
„
1894.
9
...
10
...
11
...
12
...
13
...
14
...
15
...
16
...
17
...
18
...
Temperature °C.
A.M.
39.2
38.6
38.1
40.6
39.2
39.2
39.6
40.2
39.4
39.2
P.M.
40.0
40.0
40.0
40.0
40.3
40.6
39.6
40.0
40.3
39.6
Condition of Blood.
Hæmatozoa Numerous.
„
Very numerous.
„ „
„ „
„ Few.
„
Absent.
„ „
„ „
„ Few.
„
Absent.
B 2236—46ap
183
GUINEA PIG No. XXIII.
June 30th, 1894.—Inoculated with 0.15 c.c. of blood, containing very numerous hæmatozoa, taken from Guinea Pig
No. XXI immediately after death.
Date.
June
„
July
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
1894.
29 ...
30 ...
1 ...
2 ...
3 ...
4 ...
5 ...
6 ...
7 ...
8 ...
9 ...
10 ...
11 ...
12 ...
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
19 ...
20 ...
Temperature °C.
A.M.
...
...
38.8
38.6
38.2
38.2
38.4
39.1
40.1
40.2
38.8
38.8
40.0
38.6
38.7
39.0
39.1
39.1
39.2
39.2
38.7
39.6
P.M.
...
...
39.2
39.4
39.4
39.7
39.1
40.4
40.8
39.6
38.4
40.4
40.2
39.0
39.4
39.8
39.8
39.8
39.5
39.5
39.4
39.8
Condition of Blood.
Hæmatozoa Absent.
„
„
„
„
„
„
„
„
„ Few.
„
Absent.
„ „
„ Few.
„
„
„
„
„
Absent.
„
„
„ Few.
„
Numerous.
„
„
Very numerous.
„
„
„
„
Date.
1894.
July 21 ...
„
22 ...
„
23 ...
„
24 ...
„
25
...
„
26 ...
„
27
...
„
28
...
„
29 ...
„
30 ...
„
31
...
August 1
„ 2 ...
„ 3 ...
„ 4 ...
„ 5 ...
„ 6 ...
„ 7 ...
„ 8 ...
„ 9 ...
„
10 ..
„
11 ..
Temperature °C.
A.M.
39.2
39.4
39.0
39.4
39.4
39.3
39.6
38.8
39.0
39.4
39.4
39.2
39.4
39.4
39.0
39.6
39.2
39.6
39.2
39.4
39.3
37.7
P.M.
39.8
39.8
39.8
39.6
39.8
39.7
39.8
40.0
39.5
39.6
39.4
39.5
39.6
39.6
39.8
39.5
39.6
39.6
39.5
40.0
39.4
39.2
Condition of Blood.
Hæmatozoa Swarming.
„
„
„
„
„ „
„ „
„ „
„ Very numerous.
„
Numerous.
„ Few.
„ Very numerous.
„
Swarming.
„
„
„ „
„
„
„ Very numerous.
„
Swarming.
„
„
„
„
„ „
„
„
„
„
„
„
Death.
Autopsy.—Body weight 347 grammes.
„
Spleen weight 1.7
„
„
Ratio of spleen weight to body weight 1 : 204.
RAT
SURRA.
APPENDIX IX.
TRANSMISSION OF THE HÆMATOZOON FROM THE MOTHER
TO THE OFFSPRING THROUGH SUCKLING.
CALF No I.
B 2236—47 ap
RAT SURRA.
APPENDIX X.
SUBCUTANEOUS INOCULATION OF GUINEA PIGS WITH URINE PASSED BY
ANIMALS DURING A PAROXYSM OF SURRA.
RESULTS NEGATIVE-
GUINEA PIGS (BULL No. III).
„
„ (DONKEY No. II).
197
GUINEA PIGS INOCULATED WITH URINE FROM THE BULL.
August 8th,1892.—Examined the blood of two Guinea Pigs and found it in both cases healthy. At 3-30 P.M.
injected both animals subcutaneously in the inguinal region with 2 c.c. of urine passed one hour previously by Bull
No. III, in whose blood hæmatozoa were swarming at the time. The urine was first allowed to settle for one hour ;
the supernatant liquid was then poured off, and the remaining few cubic centimetres injected.
No.
I.
No. II.
Month and
Date.
1893
August 8 ...
„ 9 ...
„
10 ...
„
11 ...
„
12 ...
„
13 ...
„
14 ...
„
15 ...
„
16 ...
„
17 ...
„
18 ...
„
19 ...
„
20 ...
„
21 ...
„
22 ...
„
23
...
„
24 ...
„
25 ...
„ 26 ...
Condition of Blood.
Before inoculation
Hæmatozoa absent ...
„
„
...
„ „ ...
„
„
...
„
„ „ ...
„ „ ...
„
„
...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
Death from accident.
Temperature °C.
A.M.
40.3
39.2
39.1
39.2
39.3
39.3
39.3
39.3
39.3
39.3
40.0
39.3
40.0
39.3
39.8
39.3
39.3
38.0
P.M.
...
40.0
40.2
40.1
39.3
39.8
39.7
40.2
40.2
40.0
40.2
40.0
37.6
39.6
40.4
40.0
40.1
35.5
Month and
Date.
1893.
August 8 ...
„ 9 ...
„
10 ...
„
11 ...
„
12 ...
„
13 ...
„
14 ...
„
15 ...
„
16
...
„
17 ...
„ 18 ...
„
19 ...
„ 20 ...
„
21 ...
„
22 ...
„
23 ...
„
24 ...
„
25 ...
„
26 ...
„ 27...
„
28 ...
„
29 ...
„
30 ...
„
31 ...
Septem. 1 ...
„ 2 ...
„
3 ...
„
4...
„ 5 ...
„ 6 ...
„ 7...
„ 8 ...
„ 9 ...
„
10 ...
„
11 ...
„ 12 ...
„ 13 ...
„ 14 ...
„
15
...
„ 16 ...
„
17 ...
„ 18...
„
19...
„
20 ...
„
21 ...
„
22 ...
„
23 ...
„
24 ...
„
25 ...
„
26 ...
„ 27 ...
„
28 ...
„
29 ...
„
30 ...
Condition of
Blood.
Before inoculation ... ...
Hæmatozoa absent ... ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „
„ „ ...
„ „
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
„ „ ...
Negative result. Observation
discontinued.
Temperature °C.
A.M.
39.7
39.4
39.3
38.0
38.6
38.6
39.0
39.0
38.0
39.0
39.3
39.0
39.3
38.7
39.7
39.3
40.2
39.7
39.0
38.5
40.1
39.1
38.1
38.0
39.3
39.1
38.6
39.2
39.3
39.3
39.3
39.8
39.8
39.0
39.1
38.0
39.6
39.3
38.8
39.7
39.3
39.6
39.3
39.3
39.7
39.1
39.6
40.0
39.3
39.7
39.3
39.8
40.0
39.3
P.M.
...
40.1
40.0
39.7
39.0
39.7
39.5
40.2
39.6
39.8
40.0
39.3
39.8
39.5
40.2
40.2
40.0
40.0
40.1
40.1
39.8
39.6
39.3
40.1
40.0
40.0
39.4
39.7
40.0
39.6
40.3
39.3
39.3
38.0
37.8
38.6
40.0
40.0
40.1
40.1
39.6
39.3
40.0
39.8
39.3
39.8
40.0
39.8
39.0
39.1
40.0
40.0
40.1
...
B 2236=50 ap
198
GUINEA PIGS INOCULATED WITH URINE FROM THE DONKEY.
August 8th, 1892.—Examined the blood of two Guinea Pigs (Nos. I and II) and found it healthy ; at 3-15 P.M.
inoculated both animals subcutaneously in the inguinal region with 2.0 c.c. of urine passed one hour previously by the
Donkey in whose blood the day previous hæmatozoa were swarming. The urine was first allowed to settle for one hour,
the supernatant liquid was then poured off, and the remaining few cubic centimetres injected.
No. I.
No. II.
Month and
Date.
1892.
August 8 ...
„
9 ...
„
10 ...
„
11 ...
„
12 ...
„
13 ...
„
14 ...
„
15 ...
„
16 ...
„
17 ...
„
18 ...
„
19 ...
„
20 ...
„
21 ...
„
22 ...
„
23 ...
„
24 ...
„
25 ...
„
26 ...
„
27 ...
„
28 ...
„
29 ...
„
30 ...
„
31...
Septem. 1 ...
„
2 ...
„ 3 ...
„
4 ...
„ 5 ...
„
6...
„
7 ...
„
8 ...
„
9 ...
„ 10 ...
„
11 ...
„
12 ...
„ 13 ...
„ 14 ...
„
15 ...
„
16 ...
„ 17 ...
„
18 ...
,.
19 ...
„ 20 ...
„
21 ...
„
22 ...
„
23 ...
„
24 ...
„
25 ...
„
26 ...
„
27 ...
„
28 ...
„
29 ...
„
30 ...
Condition of Blood.
Previous to the inoculation ...
Hæmatozoa absent ...
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
....
...
...
...
Observations discontinued.
Result negative.
Temperature °C.
A.M.
40.6
39.8
39.3
39.3
39.3
39.1
39.0
39.2
38.8
39.8
39.5
39.1
39.3
39.2
39.3
39.3
40.1
40.0
39.5
39.2
39.7
38.6
38.7
38.6
39.3
38.6
39.1
39.3
39.6
39.2
40.0
39.3
39.6
39.8
39.3
39.3
39.6
39.8
39.3
39.7
39.0
39.1
39.7
39.3
39.7
39.6
39.2
39.6
39.3
39.1
39.3
39.7
39.6
39.8
P.M.
...
40.2
40.3
40.0
40.2
39.6
39.7
40.1
40.0
40.2
40.0
40.2
39.6
39.8
40.0
39.5
40.0
40.1
39.3
39.7
40.2
40.0
40.0
40.0
39.3
39.7
39.8
39.8
39.7
39.5
40.0
39.7
39.8
39.3
38.0
39.0
39.8
40.0
40.0
40.0
39.5
39.8
40.3
39.6
40.0
40.0
40.0
39.3
39.3
39.3
39.5
40.0
39.7
Month and
Date.
1892.
August 8 ...
„
„
„
„
„
„
„
„
„
„
„
„
„
„
9 ...
10 ...
11 ...
12 ...
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
19 ...
20 ...
21 ...
22 ...
Condition of Blood.
Previous to the inoculation ...
Hæmatozoa absent
„
„ ...
„
„ ...
„
„
...
„ „ ...
„
„ ...
„
„ ...
„
„
...
„
„
...
„
„ ...
„
„ ...
Diarrhœa ; animal looks dull...
Hæmatozoa absent ... ...
Diarrhœa continues ; no hæ-
matozoa in the blood. The
red corpuscles do not form
rouleaux ; no increase in the
number of white corpuscles.
A large number of granular
protoplasmic bodies in the
blood. At 12.30 P.M. ani-
mal was very weak and
evidently dying. Death.
Temperature °C.
A.M.
40.1
39.8
40.2
39.3
38 5
39.0
39.0
39.2
39.0
40.1
40.0
39.3
39.3
35.0
P.M.
...
40.3
40.4
40.0
39.7
39.3
39.5
40.4
40.3
40.4
39.5
40.3
39.7
...
C.
BANDICOOT SURRA.
APPENDIX No. I.
INOCULATION OF ANIMALS WITH SOILED BANDICOOT'S
BLOOD.
RESULTS POSITIVE.
(A).—GUINEA PIG No. I.
RESULTS NEGATIVE.
(B).—DONKEY No. IV, MULE No. III (Vide Précis). RABBITS Nos. I, II,
III, IV.
SMALL ANIMALS INOCULATED WITH BLOOD FROM
BANDICOOT CONTAINING MINUTE SPIRILLA.
RESULTS POSITIVE.
(C).—RABBITS Nos. I, II, III, GUINEA PIGS Nos. I, II.
201
INOCULATION OF ANIMALS WITH SOILED BANDICOOT'S BLOOD.
(A)—Result Positive.
Guinea Pig I.—Inoculated with 0.2 c.c. of blood, containing swarms of hæmatozoa, taken from the heart of Bandicoot
No. IV immediately after death.
Guinea Pig I.
Date.
1894.
August
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
5 ...
6 ...
7 ...
8 ...
9 ...
10 ...
11 ...
12 ...
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
19 ...
20 ...
21 ...
22 ..
23 ...
24 ...
25 ...
26 ...
27 ...
28 ...
Temperature °C.
A.M.
...
39.2
38.7
38.8
38.2
38.6
38.4
38.4
38.2
38.8
39.4
38.6
38.1
37.5
38.8
37.8
37.8
37.5
37.8
37.8
38.2
38.0
37.0
38.2
P.M.
39.3
39.0
38.8
38.8
40.0
39.2
39.0
39.5
38.6
39.4
39.6
39.1
38.6
40.0
38.0
39.6
38.8
39.0
39.8
39.8
39.8
39.4
38.7
38.8
Condition of Blood.
Hæmatozoa Absent.
„
„
„
Hæmatozoa Few
„
„
Hæmatozoa Absent.
Hæmatozoa Few.
Hæmatozoa Absent
„
„
„
„
„
„
„
„
„
„
„
„
„
Date.
1894.
August
„
„
September
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
29 ...
30 ...
31 ...
1 ...
2 ...
3 ...
4 ...
5 ...
6 ...
7 ...
8 ..
9 ...
10 ...
11 ...
12 .. .
13 ...
14 ...
15 ...
16 ...
Temperature °C.
A.M.
38.6
38.2
37.4
38.2
38.2
37.8
38.3
37.5
37.8
37.6
37.2
38.8
37.6
37.8
38.2
38.0
37.8
35.0
Death
P.M.
39.0
39.1
39.7
39.2
39.2
39.4
39.2
39.6
39.0
39.4
39.4
38.4
38.6
38.4
39.8
39.0
38.8
...
at 12-15
Condition of Blood.
Hæmatozoa Absent.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
P.M.
Autopsy.—No marked pathological changes. Body weight
194 grammes, spleen weight 0.2 grammes. Ratio of spleen to
body weight=1 : 970.
(B)—Results Negative.
Rabbit I.—Inoculated with 0.2 c.c. of blood, containing swarms of hæmatozoa taken from the heart of Bandicoot.
No. IV immediately after death.
Rabbit I.
1894.
August
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
5 ...
6 ...
7 ...
8 ...
9 ...
10 ...
11 ...
12 ...
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
19 ...
20 ...
21 ...
22 ...
23 ...
24 ...
25 ...
26 ...
27 ...
28 ...
29 ...
30 ...
...
40.0
39.0
39.0
38.9
39.4
39.0
39.3
39.2
39.0
39.2
39.2
39.2
39.2
39.2
39.1
39.0
39.0
39.0
39.0
38.8
38.4
38.8
38.7
39.2
39.2
40.0
39.4
39.4
39.5
39.8
39.7
39.8
39.7
39.6
39.8
39.6
39.5
39.5
39.7
39.4
39.8
39.5
39.6
40.0
39.6
39.6
39.6
39.7
39.6
39.6
39.3
Hæmatozoa Absent.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
1894.
August
September
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
31 ...
1 ...
2 ...
3 ...
4 ...
5 ...
6 ...
7 ...
8 ...
9 ..
10 ...
11 ...
12 ...
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
19 ...
20 ...
21 ...
22 ..
23 ..
39.0
39.0
39.0
39.0
39.2
39.0
39.1
38.8
38.8
39.2
39.0
38.8
38.9
38.6
38.8
39.1
38.7
38.6
38.7
38.6
38.8
39.0
38.9
39.0
39.6
39.6
39.6
39.8
39.4
39.2
39.5
39.4
39.7
39.6
39.4
39.3
39.2
39.4
39.4
39.2
39.6
39.6
39.5
39.0
39.4
39.2
39.2
39.2
Hæmatozoa Absent.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
The investigation was continued for a further period of 44
days, but no hæmatozoa were observed in the blood.
B 2236—51 ap
203
Rabbit IV.—Inoculated with 0.1 c.c. of blood containing swarms of hæmatozoa taken from the heart of Bandicoot
No. XIII, immediately after death.
Date.
1894.
August
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
September
„
„
„
„
„
15...
16...
17...
18...
19...
20...
21...
22...
23...
24...
25...
26...
27...
28...
29...
30...
31...
1...
2...
3...
4...
5...
6...
Temperature °C.
A. M.
...
38.7
39.0
38.7
39.0
39.0
39.0
38.8
39.0
39.1
40.2
39.2
39.4
39.2
39.2
39.8
39.6
39.8
40.2
39.8
39.6
39.6
39.1
P.M.
39.4
39.3
39.2
39.4
39.4
39.4
39.6
39.7
39.6
39.6
39.7
39.8
40.4
40.0
40.0
41.0
41.2
40.4
40.0
40.0
40.6
40.7
40.0
Hæmatozoa
in Blood.
Absent.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
Spirilla
in Blood.
Absent.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
Few.
„
Absent.
„
„
„
„
„
Date.
1894.
September
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
7...
8...
9...
10...
11...
12...
13...
14...
15...
16...
17...
18...
19...
20...
21...
22...
23...
Temperature °C.
A.M.
39.2
39.0
39.6
39.4
39.6
39.2
39.2
38.8
39.0
39.5
39.4
39.2
39.2
38.8
39.0
39.0
38.5
P.M.
40.6
40.5
40.1
40.5
40.0
40.4
39.6
40.6
39.6
39.8
40.0
39.9
39.4
39.8
39.6
39.6
Death at
Hæmatozoa
in Blood.
Absent.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
11.30 A.M.
Spirilla
in Blood.
Absent.
„
„
„
„
Few.
„
„
„
„
„
„
„
Absent.
Few.
Absent.
Autopsy—
No marked pathological changes.
Body weight 409 grammes.
Spleen „ 1.50
„
Ratio of spleen weight to body weight 1: 272.7.
SMALL ANIMALS INOCULATED WITH BLOOD FROM BANDICOOT CONTAINING
MINUTE SPIRILLA.
(C)—Results Positive.
Rabbit I.—Inoculated with 0.3 c.c. of blood containing no hæmatozoa or spirilla taken from the heart of
Bandicoot No. I immediately after death.
1894.
September
„
„
„
„
„
„
„
October
„
„
„
„
„
„
„
„
„
„
„
23 ...
24 ...
25 ...
26 ...
27 ...
28 ...
29 ...
30 ...
1 ...
2 ...
3 ...
4 ...
5 ...
6 ...
7 ...
8 ...
9 ...
10 ...
11 ...
12 ...
...
39.0
40.4
41.2
40 .8
40.6
40.3
40.0
39.4
39.2
39.7
40.0
39.2
39.4
39.1
39.4
39.2
39.3
39.7
40.4
39.4
39.8
41.4
40.7
40.9
40.8
40.2
39.8
40.3
39.7
39.4
40.1
39.4
41.0
39.8
39.3
40.4
40.2
41.6
40.8
Absent .
„
...
„
...
„ ...
„
...
„ ...
„
..
„
...
„
...
„
...
„ ...
„
....
„
„
...
„ ...
„ ...
„ ...
„ ...
„ ...
Absent.
„
„
„
„
„
„
„
„
„
„
„
„
Few.
„
„
„
1894.
October
„
„
„
„
„
„
„
„
„
„
„
„
13 ...
14 ...
15 ...
16 ...
17 ...
18 ...
19 ...
20 ...
21 ...
22 ...
23 ...
24 ...
25 ...
39.6
38.6
39.7
38.4
38.4
38.2
39.2
38.8
38.8
39.0
38.8
38.6
39.6
39.4
39.4
38.8
39.6
39.0
39.3
39.6
39.8
39.4
39.4
38.8
Absent.
„ ...
„
...
„ ...
„
...
„ ...
„ ...
„
...
„
...
„
„
...
„ ...
Death during night.
Few.
„
„
„
„
„
„
„
„
„
„
„
Autopsy—
Spleen much enlarged.
Body weight
... 425 grammes.
Spleen weight
... 3.90
„
Ratio of spleen weight to body weight, 1 :109.