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blood extravasations, which are found only to invade the muscular structure to a limited extent.
On section,
the right side of the heart is found to contain a large quantity of clots varying in colour from a light yellow
through orange red to a dark green. The Right Auricle presents no pathological changes, but the Right Ventricle
is the seat of a large number of sub-endocardial extravasations, the musculi papillares in this case being free. The Left
Auricle presents a healthy appearance. The walls of the Left Ventricle are hypertrophied, and the cavity contains a few
dark clots. There are a few extravasations lying under the endocardial lining.
Liver.—Weighs 15 lbs. 9½ ozs., and is considerably enlarged; the capsule is free from signs of any old perihepatitis.
On section, the tissues present a yellowish-red appearance, but there are no calcareous bodies present.
Spleen.—Weighs 6 lbs. 4 ozs ; is three times the normal size; the tissues are firm, and there are a few sub-capsular
petechiæ. On section, the tissues are dark in colour, but healthy in appearance.
Kidneys.—Right organ weighs 1 lb. 8 ozs. Left weighs 1 lb. 4½ ozs. The capsules strip easily. The external portion
is pale, but presents no pathological changes.
Stomach.—Is large and on section is found to contain some semi-digested food. The coats are free from ulceration, but
there is a small spiroptera tumour on the villous portion near the boundary line.
The Small Intestines present numerous ecchymoses dotted over their whole length; and here and there small
patches are to be observed made up of aggregations of small extravasations of blood. There is however no ulceration, and
Peyer's Patches present a normal appearance.
The Cæcum presents a healthy appearance, but there are several patches of congestion involving the walls of the
Colon, but no ulceration.
The Rectum also presents a healthy appearance.
Bladder.—
Ditto.
A.—Subcutaneous inoculation and re-inoculation on two subsequent occasions with soiled fish blood—
RESULTS NEGATIVE.
B.—Further inoculation of the same animal with Horse Surra blood—
RESULT POSITIVE.
HORSE No. XLVII.
Grey country-bred horse; in fair condition and apparently healthy.
8th October 1891.—Temp. P.M. 36.8°C.
9th
10th
11th
Temp.
„
„
P.M.
„
„
36.1°C.
36.0°C.
35.8°C.
P.M.
„
„
36.8°C.
36.7°C.
37.5°C.
12th
13th
14th
Temp.
„
„
A.M.
„
„
35.8°C.
36.0°C.
35.7°C.
P.M
„
„
37.8°C.
37.6°C.
37.2°C.
On the above dates the blood presented a healthy appearance.
15th.—The animal appears healthy, the visible mucous membranes are clean and there are no petechiæ on the
conjunctivæ. The appetite is good, and the excretions normal in character. Temp. A.M. 36.3°C. Blood healthy.
At 4 P.M. inoculated subcutaneously over the left scapular region with blood mixed with 0.6 per cent. salt solution,
obtained from a large-sized fish (Barbus carnaticus). Temp. P.M. 38°C.
16th. — There is a raised, somewhat circular swelling at the seat of inoculation, tense and tender to the touch.
The general condition of the animal is unchanged. Temp. A.M. 35.7°C. No hæmatozoa. Temp. P.M. 37.5°C.
17th.—The swelling at the seat of inoculation has increased since yesterday and is surrounded by an œdematous
zone an inch in width. There are no conjunctival petechiæ. Temp. A.M. 37.5°C. No hæmatozoa. Temp. 1 P.M. 38.1°C.
Temp. 5 P.M. 38.2°C.
18th.—The swelling at the seat of inoculation has not altered in size during the past twenty-four hours,
but the tumour still feels tense, and is tender on manipulation. Temp. A.M. 36.8°C. NO hæmatozoa. Temp. 1 P.M.
38.1°C.; 5 P.M. 37.6°C.
19th.—The swelling and œdema at the point of inoculation has commenced to disappear, and the tenderness,
although present, is not so marked as previously. Temp. A.M. 36 °C. No hæmatozoa. Temp. 1 P.M. 37.5°C.;
5 P.M. 38.4°C.
20th.—The swelling and œdema have again decreased, so that the latter has almost entirely disappeared,
leaving a small somewhat circular tumour, semi-solid to the touch. The visible mucous membranes are clean, and
there are no conjunctival petechiæ present. Temp. A.M. 36.5°C. NO hæmatozoa. Temp. 1 P.M. 37.4°C.; 5 P.M. 38.3°C.
From the 21st until the 28th inclusive, the animal appeared in good health, the temperature remained normal and
no hæmatozoa were observed in the blood, but a few ecchymoses of a bright-red colour appeared on the right mem¬
brana nictitans on the 23rd.
29th.—The animal appears now to be in normal health. The visible mucous membranes are clear, and the
conjunctival petechiæ have entirely disappeared. Re-inoculated subcutaneously over the right scapular region
with blood, mixed with salt solution, taken from a specimen of carp (Barbus carnaticus). Temp. A.M. 36.6°C. NO
hæmatozoa. Temp. 1 P.M. 37.4°C.; 5 P.M. 37.7°C.
30th.—There is swelling and œdema at the seat of inoculation, exactly of the same nature as occurred after
the former injection. There is a raised, somewhat circular-shaped tumour, an inch and a half in diameter, tense and
tender on manipulation. Temp. A.M. 37°C. NO hæmatozoa. Temp. 1 P.M. 37.8°C.; 5 P.M. 38.1°C.
31st.—The swelling and œdema at the seat of inoculation have increased, and the tumour now measures 5"×4".
There are numerous recent large petechiæ on the conjunctivæ, dark-red in colour. Temp. A.M. 37°C. NO hæmatozoa.
Temp. 1 P.M. 38°C.; 5 P.M. 38°C.
1st November.—The swelling and œdema are unchanged. Temp. A.M. 37.1°C. No hæmatozoa. Temp. 1 P.M.
38.1°C. The urine is turbid, dirty yellow in colour. Sp. Gr. 1,018. Alkaline, no albumen. Temp. 5 P.M. 38.2°C.