79
HORSE No. XXVIII.
Chestnut, country-bred, aged, healthy and in good condition.
Subcutaneous inoculation with soiled rat's blood; swelling and œdema at seat of inoculation ; appearance of hæmatozoon
after latent period of 29 days; fluid in right tunica vaginalis testis; death on the 2nd day of disease ; marked
pathological lesions in heart, demonstrating virulence of the disease.
Date.
1891.
June
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July
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August
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26...
27...
28...
29...
30...
1...
2...
3...
4...
5...
6...
7..
8...
9...
10...
11...
12...
13...
14...
15...
16...
17...
18...
19...
20...
21...
22...
23...
24...
25...
26...
27...
28...
29...
30...
31...
1...
2...
Day of
Disease.
...
...
...
...
...
...
...
Temperature °C.
A.M.
...
35.7
36.5
36.1
37.0
36.8
36.6
1 P.M.
...
36.4
36.5
36.8
37.1
37.1
37.0
5 P.M.
37.7
36.6
36.6
37.0
37.2
37.8
37.1
Pulse.
A.M.
...
36
36
38
40
36
39
P.M.
40
38
40
42
46
38
43
Respiration.
P.M.
...
32
34
24
26
20
18
A.M.
28
26
30
28
30
26
32
Hæmatozoa
in Blood.
Healthy.
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Urine.
Colour.
Turbid.
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Sp. Gr.
1,018
1,022
1,030
1,036
1,020
1,042
1,034
Re-action.
Alkaline.
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Albn.
Nil
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3. P.M.—The animal was inoculated with 1.5 c.c. of blood, swarming with hæmatozoa, taken from
the rat (Mus decumanus) immediately after death. 0.75 c.c. was injected subcutaneously over
the right shoulder, and 0.75 c.c. beneath the skin on the right side of the face.
...
36.8 37.2 37.5
40
46 24 30 Absent.
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1,026
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The parts surrounding the seats of inoculation are swollen and present considerable œdema.
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35.8 36.8
37.3
36
40 22 28
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1,028
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Œdema unchanged ; some blood.-stained. fluid trickled down right nostril but contained no hæma¬
tozoa.
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36.2 36.3 36.4
38
42 24 26
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1,018
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Large ecchymoses involving the conjunctival membranes. Some swelling and œdema of the
sheath ; on pricking the sheath a nematode hæmatozoon was observed in the fluid on microsco-
pical examination.
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36.2 36.4 36.4
38
44 20 28
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1,034
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There is some swelling of the right cheek, and slight paralysis of the right buccinator muscle.
...
36.0 36.8 37.3 36
42
26 24 „
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1,042
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One nematode hæmatozoon was observed in the blood.
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36.7 36.8 36.8
34
40 24 28
One nematode hæmatozoon was observed in the blood.
...
....
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36.2
36.2
36.7
36.5
36.8
37.4
36.8
37.3
37.4
38
36
40
42
44
48
The swelling over right shoulder has
22
30
20
24
28
26
disappeared
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1,022
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1,040
1,040
1,036
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but the one on the cheek has increased in size,
and now measures 3" × 1.5".
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37.0
36.3
38.2 | 38.4
37.4 | 37.7
42
38
50
36
24 | 30
20 | 28
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1,034
1,020
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The swelling and œdema on the right cheek has increased, and there is fluid in the right tunica
vaginalis.
...
...
...
36.4
36.7
37.3
37.6
37.8
384
37.8
38.0
38.6
36
42
44
40
48
46
18
22
20
24
29
26
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1,040
1,038
1,032
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Swelling and œdema of face has now become reduced in size.
....
...
...
...
37.4
36.5
37.2
36.7
37.8
38.0
37.6
37.5
38.1
38.2
37.8
37.7
44
38
38
36
50
40
42
38
24
22
20
26
30
28
26
22
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1,034
1,026
1,020
1,032
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Annual is losing flesh ; ecchymoses involving both conjunctivæ ; the fluid has disappeared from the
right tunica vaginalis.
...
...
...
37.1
37.7
38.3
38.0
38.0
39.6
38.4
38.0
39.3
38
38
48
42
44
54
30
24
36
32
30
32
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1,030
1,029
1,032
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6 A.M.—The animal was observed to shiver ; this continued until 2 P.M. Temperature 39.6.
...
...
...
...
1
37.7
37.1
37.2
37.7
36.8
36.6
36.4
38.0
38.0
37.3
38.0
38.1
37.5
37.4
37.8
38.1
38.0
37.5
38.2
38.1
37.7
37.6
38.2
38.1
The animal continues to
2
3
38.7
37.0
38.0
37.8
37.7
38.1
44
40
38
40
36
36
36
42
50
42
44
46
40
38
40
48
28
22
26
28
20
24
18
20
28
24
30
32
28
20
26
24
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Few.
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1,040
1,034
1,034
1,028
1,022
1,040
1,029
1,030
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lose flesh.
58
60
66
72
22
18
28
24
Very nu¬
merous.
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Very nu¬ | Clear.
merous.
1,036
1,036
Faintly
acid.
Acid.
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Trace.
The animal appears to have suddenly become much weaker, but is able to stand without assistance.
Shortly after 6 P.M. the animal fell, and death took place at 8-30 P.M.
Autopsy at 10 A.M., 3rd August 1891.
The animal is fairly well nourished.