87
HORSE No. XXXV.
Subcutaneous inoculation with soiled blood of rat previously passed through one horse. Maximum swelling at seat
of inoculation on the 5th day. Appearance of the hæmatozoon after a latent period of 6 days, or 23 days less than in
the case of the direct rat inoculation. Death on the 2nd day of the disease.
Chestnut Country-Bred, aged, but apparently healthy and in fair condition.
Date.
1891.
July
„
„
„
„
„
August
„
„
„
„
„
„
„
„
„
26...
27...
28...
29...
30...
81...
1...
2...
3...
4...
5...
6...
7...
8...
9...
10...
Day of
Disease.
...
...
...
...
...
...
...
...
...
...
...
...
1
2
...
Temperature °C.
A.M.
38.6
37.2
36.7
37.4
37.3
37.0
36.8
36.7
37.5
37.4
37.2
37.3
37.1
38.4
37.4
...
1 P.M.
38.6
37.8
37.2
37.4
37.3
37.0
37.2
37.4
37.5
37.4
37.3
37.5
37.6
38.2
37.4
...
5 P.M
38.7
38.0
37.5
37.6
37.2
37.3
37.2
37.6
37.5
37.4
37.3
37.6
37.8
37.8
37.4
...
Pulse.
A.M.
30
32
32
30
28
31
33
31
30
34
32
29
36
44
48
...
P.M.
33
36
34
33
32
34
33
33
30
36
33
32
36
56
66
...
Respiration.
A.M.
12
11
11
10
11
11
10
12
12
10
12
11
12
16
18
...
P.M.
14
14
13
11
13
13
11
13
14
13
13
11
14
20
24
...
Hæmatozoa
in Blood.
Healthy
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„
„
„
„
„
Absent
„
„
„
„
Numerous.
Very nume¬
rous.
„
REMARKS.
2nd, Noon.—The animal was subcu¬
taneously inoculated over the left
shoulder with 0.5 c. c. of blood contain
ing very numerous hæmatozoa, taken
from the internal jugular vein of
Horse No. XXVIII.
3rd.—Considerable swelling and œdema
at the seat of inoculation.
4th.—The swelling at seat of inoculation
has increased, and is tense and tender
on manipulation.
5th.—
Do.
do.
6th.—The swelling and œdema at seat of
inoculation has further increased, and
is now very tense and tender, the animal
resenting manipulation.
7th.—
Do.
do.
8th.—A few petechiæ are now present on.
the conjunctival mucous membranes,
and the swelling and œdema have dimi
nished in extent.
9th.—Swelling and œdema still further
reduced in size.
10th.—The animal became weaker during
last evening, and death occurred at 4 A.M.
Autopsy at 10 A.M.
The body is fairly nourished.
Thorax.—No fluid in the thoracic cavity or adhesions of the pleuræ.
Right Lung.—The apex is consolidated, and on section, each individual lobule is seen to be mapped out by a narrow
layer of a brownish yellow-coloured jelly which nowhere exceeds 1/12th of an inch in width. The pleura is thickened
and opaque in patches over the middle third of the superior surface. The surface of the lung is dark in colour, for the
most part caused by large numbers of extravasations of blood, varying in size from 1/6th to ¾th inch in diameter, circu
lar or irregular in outline, and slightly darker in the centre of the patch than at the circumference. On passing the
hand over the surface of the organ, hard circumscribed lumps are felt, varying in size from a pea to a small walnut.
There are also several small ones lying on or very near to the surface of the organ ; whilst others can be felt in the
substance of the tissues. On section, the centres of these bodies are found to be occupied by caseous material, yellow in
colour ; and externally, there are zones of inflammatory material, which in time would have encapsuled them.
Left Lung.—There are superficial extravasations and nodules, exactly the same as those observed in the Right Lung.
The anterior portion of the organ is consolidated for a distance of 8", running back from the apex. On section, this
portion presents a layer of the brownish yellow jelly, lying between and completely surrounding the individual lobules.
In this situation the exudation is quite ⅛th of an inch in thickness in isolated patches.
There is a little fluid in the pericardium.
Heart.— Weight 4 lbs. 15½ ozs. Externally the base is surrounded by a certain amount of a gelatinous material.
There are extensive extravasations of blood lying beneath the visceral pericardium on the right auricle and ventricle,
and others as extensive in the auriculo-ventricular groove accompanying the coronary vessels. There are a few smaller
ones dotted over the surface of the left ventricle.
The Right Auricle is distended with an orange coloured clot, and there are a few sub-endocardial ecchymoses.
Right Ventricle contains a large clot externally dark-red, but its centre is of a bright orange colour. There are
numerous and extensive sub-endocardial extravasations, very dark in colour. The larger ones lie longitudinally from the
base to the apex of the organ. Two are 1½" in length by ½" in width, and on transverse section present a semi-circular
form. There are a few small circular-shaped subendocardial ecchymoses on the flaps of the tricuspid valve.
The Left Auricle contains a dark clot, and there are a few subendocardial ecchymoses.
The Left Ventricle presents a similar condition to that described as found in the Right, with. this exception that the
extravasations are rather smaller ; and consequently there is more healthy tissue showing between the dark coloured
patches.