105
6th April 1891.—There is a small blood clot at the inner canthus of the left eye due to a rupture of one of the
vessels of the conjunctiva. Temperature A.M. 38.3°C. No hæmatozoa observed. Temperature P.M. 38.4°C.
From the 7th to the 9th there was no change in condition.
10th.— This morning a small lump about 1/3" in diameter globular in form and hard to the touch, can be felt at
the seat of the inoculation. Temperature A.M. 38.2°C. NO hæmatozoa observed. Temperature P.M. 38.5°C.
11th.—The swelling at the seat of inoculation on the muzzle has increased in size and is tender on pressure.
Temperature A.M. 38.6°C. One hæmatozoon observed in two cover-glass preparations of the blood. Temperature
P.M. 38.8°C.
12th.—Temperature A.M. 40.2°C. Hæmatozoa few. Temperature P.M. 40.1°C.
13th.—
„
39.8°C.
„
„
„
39.9°C.
14th.—The patient is dull, and is rapidly losing flesh. Temperature A.M. 39.6°C. Hæmatozoa very numerous.
Temperature P.M. 39.8°C.
15th.—The tumour on the muzzle, which was large and tense yesterday morning, has now almost entirely
disappeared. Temperature A.M. 39.5°C. Hæmatozoa very numerous. Temperature P.M. 39.8°C.
16th.—There is a slight discharge of blood from the right nostril. Temperature A.M. 40.7°C. Hæmatozoa very
numerous. Temperature P.M. 40.9°C.
17th.—Temperature A.M. 40.1°C. Hæmatozoa very numerous. Temperature P.M. 40.5°C.
18th.—Temperature A.M. 39.5°C. No hæmatozoa observed. Temperature P.M. 39.6°C.
19th.—All four limbs are œdematous, and the animal is weaker. Temperature A.M. 39.4°C. NO hæmatozoa
observed. Temperature P.M. 40.1°C.
20th. — Temperature A.M. 39.8°C. No hæmatozoa observed. Temperature P.M. 39.9°C.
21st.—At 7 A.M. there was a slight discharge of blood from both nostrils ; the animal was standing with its head
down, eating hay placed on the ground, and the hæmorrhage lasted for 6 or 7 minutes. The appetite is very good.
Temperature A.M. 37.8°C. Hæmatozoa few. Temperature P.M. 38.1°C.
22nd.—The œdema of the limbs is much less marked this morning owing to the animal having assumed the
recumbent position during the night. Temperature A.M. 38.1°C. Hæmatozoa few. Temperature P.M. 39.2°C
23rd.—Temperature A.M. 39.4°C. Hæmatozoa very numerous. Temperature P.M. 39.7°C.
24th.—There is slight collection of mucus, mixed with blood, at the inner canthus of both eyes, which on
examination is found to contain hæmatozoa. Temperature A.M. 40.2°C. Hæmatozoa very numerous. Temperature
P.M. 40.1°C.
25th.—Hæmorrhage from the left nostril occurred at 5 A.M. this morning, and lasted for a few minutes. The
appetite remains good, and the evacuations are normal. Temperature A.M. 40.3°C. Hæmatozoa numerous.
Temperature P.M. 39.8°C.
26th.—In the early morning the animal was unable to rise, and gradually became weaker, Death occurred at
11.30 A.M.
Autopsy.—15 minutes after death.
The animal is considerably emaciated, and the fore and hind limbs are
œdematous. There is no fluid in
the pleural cavities, and no pleuritic adhesions.
Lungs.—The lungs present a pale and somewhat collapsed appearance, and the superior and inferior surfaces of
both organs are dotted over with dark-purple patches varying very much in size, from that of a pea to 1" in length
and ½" in width. These extravasations are lying under the visceral pleura, and on section, are found to dip down and
invade the lung-tissue to the extent of ¼" to 1/3". These patches are seen dotted over the cut surfaces of the organ, and
are lying some distance apart. The major part of the section presents a mottled yellowish pink colour. Besides the
condition already described, one notices, on passing the fingers over the surface of the organ, numerous small elevations
which are hard and gritty to the touch, and on taking up a portion of the lung between the fingers, others are felt
imbedded deeper in the structures. These hard bodies are found to be small concretions, which in some cases are
readily enucleated, and contain a yellowish-coloured soft material like paint.
The pericardium contains several ounces of a saffron coloured fluid.
Heart.—Weighs 3 lbs. 2½ ozs. Nothing abnormal is noticed on the pericardial surface. On section, the valves
are normal, and there are no sub-endocardial extravasations.
Liver.—Is somewhat enlarged. There is some perihepatitis involving the left lobe, and the right lobe presents
a slight opalescence of Glisson's capsule. On the surface of the organ are seen, dotted about, round spots, whitish
in colour, which on section are found to invade the gland substance.
Spleen.—Weight 2 lbs. 11½ ozs., fairly firm to the touch. The surface of the organ presents several small petechiæ
irregular in outline, and of a brownish red colour.
Stomach.—On palpitation, one can feel a somewhat large mass involving the coats of the under-surface of the organ,
some three inches from the pylorus. On section, the organ contains a certain amount of semi-digested green food mixed
with undigested gram and corn. A tumour is noticed lying midway between the cuticular portion and the pyloric
orifice, the left side of which reaches the edge of the limiting membrane. The tumour is almost circular in shape, 4" in
diameter and 1½" at its greatest thickness in the centre, and 1 1/16" in thickness at the circumference. The mucous mem-
brane covering the tumour is of a pinkish red colour, considerably thickened, and presents a puckered appearance with
a depression in the centre. On section, the tumour presents a cavity lined by a dark membrane, and containing a semi-
solid, fœtid-smelling, yellow mass, which on microscopical examination is found to be composed of pus cells, crystals
and debris. The cavity is 2½" in diameter, ½" from the floor to the highest part of the roof, and 3/8" at the circumference.
Its walls are ½" to ¾" in thickness, and present a dark slate-coloured hue ; whilst on its floor, there are some small
blood extravasations in its substance. Externally, the wall is pinkish white in colour, firm to the touch, and appears
to be made up of white fibrous tissue. The tumour contains the spiroptera megastoma.
Kidneys.—The capsules strip easily. There are no petechiæ on the surface of the organs.
Intestines.—Present a healthy appearance.
B 2236-27 ap