129
August
„
„
„
„
„
„
„
„
„
„
„
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
September 1.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
Temperature
„
„
„
„
„
„
„
„
„
„
„
„
A.M. 38.4°C.
„ 39.1°C.
„ 38.3°C.
„ 38.7°C
„ 38.4°C.
„ 38.4°C.
„ 40.7°C.
„ 38.8°C.
„ 39.7°C.
„ 39.1°C.
„ 39.7°C.
„ 39.5°C.
„ 38.6°C
P.M.
„
„
„
„
„
„
„
„
„
„
„
„
39.2°C.
39.1°C.
39.2°C.
38.8°C.
39.0°C.
39.1°C.
39.1°C.
39.2°C.
39.3°C.
39.2°C.
39.4°C.
39.6°C.
39.2°C.
No hæmatozoa in the blood.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
The animal was re-inoculated with 0.5c.c. of blood containing numerous hæmatozoa, taken from the heart
of a rat (Mus decumanus) immediately after death. Temperature A.M. 38.7°C. NO hæmatozoa in the
blood. Temperature
Temperature
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
A.M. 39.0°C.
„ 39.1°C.
„ 39.1°C.
„ 39.0°C.
„ 37.8°C.
„ 38.3°C.
„ 38.3°C.
„ 38.4°C.
„ 39.5°C.
„ 38.3°C.
„ 38.8°C.
„ 40.0°C.
„ 39.2°C.
„ 38.3°C.
„ 40.6°C.
„ 40.0°C.
„ 38.5°C.
„ 38.0°C.
„ 38.2°C.
„ 39.5°C.
„ 38.0°C.
„ 38.2°C.
P.M.
P.M.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
39.3°C.
39.5°C.
39.7°C.
39.4°C.
38.6°C.
39.1°C.
39.0°C.
39.1°C.
39.2°C.
39.7°C.
39.4°C.
38.8°C.
41.1°C.
39.4°C.
39.0°C.
39.6°C.
39.8°C.
38.5°C.
38.6°C.
40.7°C.
39.2°C.
39.1°C.
39.3°C.
No hæmatozoa in the blood.
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
„
The animal appears to be ill, but it runs about the cage as usual. Temperature A.M. 40.9°C. NO hæma¬
tozoa in blood. Temperature P.M. 39.5°C.
Condition unchanged. Temperature A.M. 40.8°C. No hæmatozoa in the blood. Temperature P.M. 39.3°C.
„
„
„
„
„ „
„ „
39.6°C.
40.4°C.
„
„
„
„
„
„
„
„
39.4°C.
39.5°C.
The breathing is quickened, and the animal is dull and sleepy. Temperature A.M. 40. O C. No hæmatozoa
in the blood. Temperature P.M. 40 °C.
Condition worse. Temperature A.M. 38.6°C. No hæmatozoa in the blood. Temperature P.M. 38.7°C.
October 1. Temperature A.M. 35.2°C. Death.
Post mortem.— The body is well nourished.
Lungs.—Both organs are dotted over with small dark purple irregular shaped petechiæ, many being only the size
of a pin's head. The base of the right inferior lobe is covered with a layer of yellow lymph about a line in thickness.
Pericardium.—Is distended with clear fluid. There is no pericarditis.
Heart.—Healthy.
Liver.—Large, firm ; on section, the tissues appear healthy.
Spleen.—Small ; on section, tissues present a healthy appearance.
Stomach.— Healthy.
Bladder.— Do.
Kidneys.— Do.
Remarks.—This animal was inoculated sub-cutaneously on the 5th of August 1891, with 0.5c.c. of blood containing
numerous hæmatozoa taken from the heart of a rat (Mus decumanus) immediately after death. The temperature of the
animal rose slightly on the 9th, and there was an increase of white corpuscles in the blood, together with masses of
colourless protoplasm, but no hæmatozoa. As no symptoms of Surra had developed by the 2nd September 1891. the
animal was re-inoculated sub-cutaneously with the same quantity of blood from a similar source. On the 14th Sep¬
tember, the temperature rose in the morning to 40°C. and in the evening to 41°C., but no hæmatozoa appeared in the
blood.
The following morning the temperature was normal, and the animal appeared healthy. On the morning of the
25th September, the temperature had risen to 40.9°C. and the animal appeared ill, but the blood on microscopical
examination revealed nothing. On the 29th the breathing was quick and the animal presented a dull, sleepy appearance.
Death took place on the 1st October 1891. The autopsy revealed the presence of pleurisy and the surfaces of the lungs
were petechiated, otherwise the organs were healthy.
Two Guinea pigs inoculated with fluid from the pericardial sac gave negative results.
B 2236-33 ap