56
The average amount of urea and urine excreted daily for the whole period of health and disease, viz., 409 days,
corresponds closely with that given as the average for horses at work, in England, viz., 80.33 grammes urea, and
4.437 litres urine.
HORSE No. XCVI.
Entire C. B., aged, in somewhat poor condition. The animal is now free from disease, though it had a few weeks
previously been suffering from slight fever, accompanied by the ordinary symptoms. The appetite is good and the
excreta normal in appearance.
The following experiment was undertaken with a view to determine as in the previous case No. LXXXIX :—
(i) "Whether the administration of Arsenic immediately upon the appearance of the Surra hæmatozoon would prove
destructive to the organism, when the disease was contracted by gastric ingestion of blood, in a manner somewhat
similar to that in which it ordinarily occurs in nature.
(ii) The ratio between the quantity of water drunk, irrespective of the amount of fodder, and quantity of urine
passed during 24 hours.
(iii) The excretion of Nitrogen as Hippuric Acid and Urea, during the periods of health, latent period of the
disease, paroxysms and intermissions, the animal being under treatment during the two latter periods.
Date.
1893.
October
„
„
„
„
„
„
„
„
„
„
„
„
„
November
„
„
„
„
„
„
„
„
„
„
18...
19...
20...
21...
22...
23..
24...
25...
26...
27...
28...
29...
30...
31...
1...
2...
8...
4..
5..
6..
7..
8..
9..
10..
11..
Day of
Disease.
...
...
...
...
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
Temperature °C.
A.M.
36.5
36.4
36.4
35.6
36.2
36.4
36 .0
35.8
37.3
38.5
38.8
38.1
37.4
36.8
36.6
36.0
36.0
35.8
35.4
35.6
35.2
35.7
36.4
35.8
35.8
P.M.
37.4
37.0
36.8
36.1
36.8
37.0
30.6
37.7
38.3
40.1
39.5
38.0
37.2
38.2
37.7
37.2
37.2
37.0
37.9
36.5
36.6
37.8
36.4
37.1
...
5 P.M.
38.2
38.2
37.5
37.0
37.2
37.7
37 .7
37.5
39.1
40 6
39.0
38 6
37.7
38.2
37.8
37.4
37.2
37.7
37.4
37.0
37.2
36.8
37.0
36.0
...
Pulse.
A.M.
40
44
28
28
32
28
48
28
36
32
36
48
56
60
44
44
40
61
36
40
32
36
40
44
48
P.M.
44
32
36
36
32
36
36
36
36
56
52
56
48
64
52
52
56
52
52
44
44
40
44
36
...
Respiration.
A M.
16
12
12
12
12
8
12
12
12
12
16
24
24
16
16
16
12
12
8
12
12
12
12
12
12
P.M.
16
16
16
12
16
16
16
16
12
28
28
16
28
36
20
24
16
20
16
16
12
24
12
16
...
Death at 12-5 P.M.
Hæmatozoa
in Blood.
Absent.
...
...
...
...
...
...
Few
Very
numerous.
Swarming
„
Very
numerous.
Absent.
„
„
„
„
„
„
„
„
„
„
„
Medicine
Arsenic
(Grains).
A.M.
...
....
...
...
...
...
...
iv
v
v
vi
vi
vi
vi
vi
vi
vi
vi
vi
vi
vi
vi
...
P.M.
...
...
...
,„
...
...
iv
iv
v
v
vi
vi
vi
vi
vi
vi
vi
vi
vi
vi
vi
vi
...
REMARKS.
18th, 3 P.M.—Administered by mouth
4 ozs. of blood containing very nu-
merous hæmatozoa taken from the
jugular vein of Horse No. XCV im-
mediately after death.
19th.—Condition unchanged.
20th.—
Do.
do.
21st.—
Do.
do.
22nd—
Do.
do.
23rd.—
Do.
do.
24th.—
Do.
do.
25th.—There are petechias on the right
conjunctiva, which membrane is in-
jected ; left, clear but yellow. The
nasal septum is petechiated.
26th.—Animal dull, but appetite good,
injection of conjunctivas unchanged.
27th.— Conjunctivae injected; right;
petechiated; other visible mucous mem-
branes also injected ; testicles swollen.
28th.- Both conjunctivae petechiated ;
general condition unchanged.
29th.— Animal gradually losing flesh.
Conjunctivas injected and petechi-
ated.
30th.- Animal getting weaker, but the
appetite continues good.
31st.- Conjunctivas still much injected
and petechiated. Fæces pultaceous in
character.
1st.—
Do.
do.
do.
Hind legs swollen from below hocks.
2nd.—
Do.
do.
do.
Animal little brighter.
3rd.—Animal brighter and stronger.
Conjunctival membrane yellow and
petechiated; slight discharge from
the nose.
4th.—Animal dull; general condition
unchanged.
6th.- Animal stronger; conjunctivas still
injected and petechiated, nasal mu-
cous membrane dotted with bright
red spots.
7th.—General condition unchanged ;
discharge from the nostril continues.
8th.-
Do.
do.
do.
9 th.—
Do.
do.
do.
10th.—Animal very thin ; condition of
the mucous membranes unchanged.
11th, 9-30 A.M.— The animal suddenly
fell. Chloroform was administered
at 11.45 A.M.