NationalLibraryOfScotland/medical-history-of-british-india huggingface dataset:
59
Temperature in rectum 100 . 6 F. Carotid artery ligatured at 2h. 38m. Canula
inserted at 3h. 40m. 30s. Ligature placed under both vagi. Junker's lead
tube inserted into an opening in the trachea and the chloroform administered
through it. Connection made with manometers at 3h. 5m. 30s., but stopped.
again almost immediately on account of bleeding from the artery below the
canula. Connection again made at 3h. 19m. 15s. One Ludwig' and one Fick
tracing. During the tracings numerous attempts were made to irritate the
right vagus, but it is not probable that the nerve had really been exposed. The
canula slipping at 3h. 38m., an attempt was made to place it in the right carotid,
but failed, and the experiment was closed by killing the monkey with chloroform.
November 8th.—No. 69.
Temperature of room 25 Cent. Full-sized pariah dog just brought in.
Into chloroform box at 4h. 6m. Fallen down at 4h. 12m. 20s. Placed on the
table at 4h. 13m. 30s. Artery ligatured at. 4h. 18m. 50s. Breathing stopped
at 4h. 19m. 40s. Artificial respiration until 4h. 20m. 30s. Temperature in
rectum 103.2 F. Connection made with manometers at. 4h. 29m. 30s. TWO
Ludwig and two Fick tracings.
Observations .
I I . M . S ,
A. 4 32 0.—Electrical irritation of the entire left vagus with the
coils 5 cent. apart.
B. 4 33 0. —The same. Fi ck r eadi ng 2.
C. 4 35 10.—The same, only coils approached to 0. Fick 3.
P. 4 39 10.—The same,
E. 4 39 55.—Administration of chloroform, during which the right
v a g u s
w a s a c c i d e n t a l l y i r r i t a t e d i n t h e p r o c e s s o f
exposing it.
F. 4 41 30.—Electrical irritation, coils 0, of the entire right vagus,
the animal being nearly out of chloroform.
G. 4 42 10.—The same. Fick reading 6.
H 4 50 0.—Exposure of the sciatic nerve.
4 51 15.—Irritation of the right vagus as before with simultaneous
irritation of the sciatic nerve.
J. 4 54 0.—The same. Fick reading 7.
K, 4 54 30.—Ordinary administration of chloroform.
L. 5 1 0.—Repetition of I and K when the dog was " well under,"
vide Fick 9.
60
H . M .
s .
M. 5 5 0.—Administration of ether on a sponge placed in a tin
inhaler with the air-holes open.
N. 5 9 0.—Repetition of I, K, and M, under ether.
O. 5 13 0. —The s a me . Vi de Fi ck 11 t he ef f ect of i r r i t at i ng t he
vagus not marked as before.
P. 5 16 0.—Division of the right vagus.
Q. 5 20 0.—Irritation of the peripheral end of the right vagus
while still under ether.
R. 5 21 0.—Ditto when dog " quite out". Chloroform was then
pushed until death resulted. the heart stopping at
5h. 25m. But the tracing was interrupted by a clot
in the tube.
November 9th.—No. 70.
Temperature of the room 20 Cent, Large-sized pariah dog. Into
chloroform box at 9h. 42m. 50s. Fallen down at 9h. 45m. 15s. On the table at
9h. 47m. Left carotid artery ligatured at 9h. 53m, 15s. and canula inserted into
it. Loose ligature under right carotid and both vagi. Connection made with
manometers at 10h. 2m. 40s. Two Ludwig and one Fick tracings.
Observations.
H . M . S .
A. 10 3 30.—Clamping the right carotid artery so that both carotids
were obstructed.
B. 10 6 40.—Administration of ether in an open inhaler, through
which there was free entrance of air during the clamp-
ing of the carotid and after the clamp was taken off.
C. 10 17 35.—Ligature and division of the right vagus.
D. 10 19 10.—Peripheral irritation of the right vagus with a 5 cent.
coil. Cornea insensitive.
E.
1 0
2 0 1 5 . — R e p e t i t i o n o f D ,
v i d e
F i c k r e a d i n g7
.
F. 10 22 0.—Exposing sciatic nerve.
G. 10 24 10.—Irritation of the sciatic nerve, coil 5. No effect.
H.
1 0 3 7 3 5 . —O p e n i n g t h e t r a c h e a a n d f i x i n g a t u b e i n i t .
I 1 0 3 9 5 5 . — A d m i n i s t r a t i o n o f e t h e r o n a b l o t t i n g p a p e r c o n e h e l d
over the end of the tracheal tube. This, however,
-failed to keep the dog insensitive, although a little
ether was squeezed into the tube.
61
H. M. s.
J. 10 48 40.—Continued ether administration with the end of the
tube closed by compressing the cone and afterwards
by squirting a little ether into the trachea.
K. 10 51 50s,—Artificial respiration in vain.
Temperature after death 97 .6 F. Post-mortem—Blood on both sides of
the heart; large plug of venous blood at the bifurcation of the trachea
extending far down into the bronchi, probably the result of blood running into
trachea, post-mortem, when the tube was taken out, as this was observed to
happen in No. 71 after the tube was taken out. The upper readings on the Fick
manometer tracing were produced by a system of Marey's tambours connected
with a pin stuck into the diaphragm.
November 9th.—No. 71.
Temperature of room 22 . 5 Cent. Full-sized pariah.. Weight 30 lbs. Into
box at 11h. 21n. 40s. and chloroform commenced. Fallen down at 11h. 6m.
10s. On table a.t 11h. 9m. 45s. kept quiet with chloroform. Respiration
stopped at 11h. 12m. Artificial respiration directly this was observed and Con-
tinued till 11h. 12m. 50s, when spontaneous respiration recommenced. A good
deal of hæmorrhage from vessels in the neck. Two veins and one small artery
ligatured. Artery ligatured at 11h. 25m. Canula inserted at 11h. 26m. 30s.
into left carotid. Loops under both vagi, the right carotid and trachea. Tem-
perature in rectum 994 F. Connection made with manometer at 11h. 331n. 55s.
TWO Ludwig and one Fick tracing.
A. 11 35 40.—Clamping of the right carotid so as to close both
carotid arteries.
B. 11 38 20.—Exposing the sciatic nerve.
C. 11 38 50.—Ordinary chloroform administration.
D. 11 40 40.—Irritation of the sciatic coil 5 when hardly under
chloroform, which was being pushed.
E. 11 41 3O.—Ligature and division of right vagus.
F. 11 47 10.—Irritation of sciatic again after administration of
chloroform had ceased, but dog still under.
G. 11 47 30.---Irritation of the sciatic again, but in the middle increas-
ing the strength by moving the coil to 0 (Fick read-
ing 6). The irritation of the sciatic produced no effect.
11 50 O.—Opening the trachea and placing a tube in it.
62
H. M. S.
I. 11 52 0.—Giving chloroform on a cone of blotting paper attach-
ed to the tracheal tube.
J . 1 2 0 4 0 . — A d m i n i s t r a t i o n o f e t h e r i n t h e s a m e w a y f o r a f e w
seconds by mistake.
K. 12 4 0.—Pulling at the right vagus
.
L . 1 2 4 5 0 . — I r r i t a t i o n o f t h e p e r i p h e r a l e n d o f t h e r i g h t v a g u s ,
coil 5 during continued pushing of chloroform.
M. .....
Irritation of both right vagus and sciatic during
continued pushing of chloroform. Stoppage of the
respiration at 12h. 8m. 0s. and spontaneous re-
covery at 12h. 9m. 45s.
N. 12 10 30.—Squirting ½ a drachm of chloroform into the tracheal
tube, and
—
O. 12 11 30.—Irritation of the right vagus again. The end was
obscured by a clot in the tubes.
Temperature at death 98 F.
November 9th.—No. 72.*
Temperature of the room 23·5 Cent. Full-sized pariah dog. Weight
30 lbs. Into the chloroform box and chloroform given at 2h. 21m. 50s.
Placed on the table at 2h. 25m. 35s. and kept quiet with chloroform. Stopped
breathing at. 2h. 24m. 15s. Artificial. respiration until 2h. 35m. 45s. Tempera-
t u r e 1 0 8 8 F . i n t h e r e c t u m. Le f t c a r o t i d l i g a t u r e d a t . 2 h . 3 6 m. 4 5 s .
R i g h t j u g u l a r v e i n l i g a t u r e d a n d c a n u l a i n s e r t e d a t 2 h . 5 2 m . C o n n e c t i o n m a d e w i t h
the manometer at. 2h. 53m. 30s. One Ludwig and one Fick tracing showing
the effect of injecting ether and afterwards chloroform into the jugular vein.
Temperature after death 102 . 2 F. Post-mortem—the blood in the left side of
the heart was clotted.
O b s e r v a t i o n s
—
A. 2h. 58m. 45s.—Fifteen minims of ether injected into the jugular
vein : no appreciable effect. At 2h. 59m. 40s. twenty minims of ether
were again injected. Between 3h. 1m. 0s. and 3h. 1m. 30s. one drachm of
ether was injected into the jugular vein and the blood-pressure fell very
rapidly. The respiration stopped at 3h. 2m. 0s. and the Fick reading 2
shows almost total arrest of the pulse tracing exactly similar to that caused
* Nos. 72 and 73 may be grouped with Nos. 77, 91, 92 and 93.
63
by vagus stimulation after cessation of the respiration from chloroform
poisoning. At 3h. 2m. 20s. artificial respiration was commenced and
natural respiration was restored at 3h. 4m. 30s.
B. 3h. 8m. 30s.—Twenty minims of chloroform injected into jugular
vein. The effect was precisely the same as that of the intravenous injec-
tion of ether. Fick reading 4 with chloroform is identical. with Fick
reading 2 with ether. This and other experiments, when pure chloroform
and. ether were injected into the large veins of the neck, show that- even
pure chloroform or ether in the blood do not stop the heart till after they
have produced narcosis and paralysed the respiration.
The most important point in Experiment 72 is that after a considerable
amount of ether had been injected into the jugular vein and a rapid condition
of pulse had been produced, the effect of injecting chloroform into the jugulars
was much greater, and the fall of blood-pressure was much more rapid and
dangerous than in the case when chloroform alone was injected.
November 9th.—No, 73.*
Temperature of the room 24 Cent. Full-sized pariah. Weight 32 lbs.
Put into chloroform box at 3h. 28m. Fallen down at 3h. 35m. 40s. Placed
on t he t abl e at 3h. 36m. 30s. Temperat ure 102· 2 F. i n rect um, Jugul ar vei n
ligatured and canula inserted. Left carotid ligatured at 3h. 45m. Connection
made with the manometers at 3h. 50m. One Ludwig and two Fick tracings
during injection of ether (Fick 2) into jugular vein, afterwards chloroform
(Fick 5) and again ether (Fick 9), which brought about death. Temperature
after death 100 F. Post-mortem—Small clot in the left ventricle, which was
filled with venous blood, clot in superior vela cava. Serous fluid in the
pericardium.
O b s e r v a t i o n s .
H. M. S.
A. 3 53 10,—Injection of twenty minims of ether into deep jugular
vein ; repeated at 3h. 53m. 35s., 3h, 54m, 5s., and
3h. 54m. 30s. The effect is shown in Fick reading 2.
B .
3 5 9 4 0 . — I n j e c t i o n o f t w e n t y m i n i m s o f c h l o r o f o r m i n t o j u g u l a r
vein ; the effect, is shown in Fick reading 5 and is
identical with that produced by ether.
*Nos. 72 and 73 may be gr ouped wi t h Nos, 77, 91, 92 and 93.
64
C. 4 5 55.—Injection of twenty minims of ether. See Fick read-
ing 9. The injection was followed by rapid fall
of pressure; the respiration stopped at 4h. 6m. 40s.;
gasping took place at 4h. 8m. 0s.;the thorax was
opened at 4h. 9m. 0s., and the heart was found still,
with a clot in the left ventricle. The disastrous
effect of injecting ether after chloroform is well
shown in this experiment.
November 11th.—No. 74.
Temperature of the room 19.5 Cent. Rather small pariah dog. Weight
21 lbs. Into chloroform box at. 8h. 13m. 30s. Fallen down at. 8h. 17m.
Placed on the table at 8h. 21m. 50s. Temperature in the rectum 100 .4 F.
Left, carotid ligatured at 8h. 28m. 10s. Right jugular vein ligatured at 8h.
33m. and canula inserted into left carotid 8h. 44m. Connection made with
the manometers at 8h. 46m. 15s. Two Ludwig and three Fick tracings.
Observations.
H . . M . . S .
A. 8 47 30.—Ordinary chloroform. administration.
B. 8 48 20.—Thrusting a needle into the heart.
C. 8 49 25.—Irritation with a 10 cent. coil of the right, vagus entire,
(Fick reading 3).
D.
D. 8 51 5. —Chl or of or m a ga i n r a pi dl y. St oppa ge of r e s pi r a t i on a nd
recovery with artificial respiration.
E.
9 0 0.—Injection of atropine 1-50th grain into the jugular vein.
F.
9 6 40.—Chloroform administration again during struggling
the respiration again stopping and necessitating
artificial respiration.
G. 9 14 25.—Irritation of the right entire vagus.
H. 9 16 50.—Injection of 1-25th grain of atropine into jugular vein.
I. 9 22 5.—Irritation of right vagus again when animal under
influence of atropine. Coils moved from 10 to 5
and then to 0 (Fick 13).
K . 9 3 4 3 0 . — P u s h i n g c h l o r o f o r m u n t i l d e a t h .
Heart was still beating 3 minutes after the pulse became imperceptible.
Temperature after death 97.4 F.
Post-mortem—Two drachms of blood in the pericardium ; no clot in heart.
65
November llth.—No. 75.
Monkey (Macacus). Weight 15 lbs. Into chloroform box at 10h, 29m. 50s.
Fallen down at 10h. 34m. 30s. Placed on the table at 10h. 47m. and kept quiet
with chloroform from time to time. Temperature in the rectum 101 . 8 F. Loop
under both vagi. Artificial respiration 10h. 57m. 15s. to 10h. 58m. 5s. Left
carotid ligatured at 11h. lm. 30s. Canula inserted at 11h. 4m. 50s. Connection
made with manometer at 11h. 18m. 10s. Two Ludwig and two Fick tracings.
Observations.
H . M . s .
A. 11 19 0—Ordinary chloroform administration.
B. 11 21 20.—Holding ammonia before the nostril.
C. 11 24 40.—Holding acetic acid before the nostril.
D. 11 26 0—Dropping a few minims of chloroform into the nostril.
E. 11 45 50.—Irritation of the entire right vagus, coil at 10 cents.
(Fick 4).
F. 11 48 0.—The same with the Ludwig manometer connected.
G. 11 53 0.—Irritation of the entire right vagus, coil at 5 (Fick 5).
H.
11 58 40.—Irritation of the right vagus, coil at 0 (Fick 6).
J. 12 2 20.—Thrusting needle into the heart.
K. 12 3 45.—Pushing chloroform until death.
Needle entered the left ventricle. Temperature soon after death 97 F.
November 11th.—No. 76.
(In the presence of His Highness the Nizam.)
Pariah dog. Weight 37 lbs. Temperature of the room 23·5 Cent. Into
chloroform box at 2h. 21m. 36s. Fallen down at 2h. 28m. 30s. Placed on the
table at 2h. 30m. 50s. and kept quiet with chloroform. Artificial respiration
at 2h. 40m. 25s. and until 2h. 44m. 15s. Carotid ligatured at 2h. 41m. 5s.
Temperature in the rectum 100 F. Loop under both vagi. Connection made
with manometer at. 2h. 48m. 25s.-Two Ludwig and two Fick tracings.
Observations,
H . M .
s .
A. 2 48 25.—Ordinary chloroform administration in several in
stances.
B. 2 51 50.—Irritation of right vagus repeatedly (Fick 2-4).
C. 3 34 5.—The same after the injection of atropine into the
jugular veins (Fick 6).
9
66
H. M. s.
D. 3 40 0.—Thrusting needle into heart,
E. 3 42 30.—Inhalation of ammonia.
F. 3 43 0.—Pushing chloroform until after respiration had com-
pletely stopped, and then
G. 3 46 0.—Restoration by artificial respiration.
H. 3 48 20.—Pushing chloroform until death resulted.
Temperature after death 99 .4 F.
November 12th.—No. 77.
Temperature of the room 18·5 Cent. Medium-sized pariah 26 lbs. Into
chloroform box at 7h. 27m. 12s. Fallen clown at 7h. 36m. 50s. On the table
at 7h. 38m. 50s. Artery ligatured at 7h. 50m. 10s. Temperature in the rectum
99 . 2 F. Canula inserted into the left carotid at 7h. 58m. 50s. Right jugular
ligatured at 8h. 3m. 10s. Connection made with manometer at 8h. 13m.
Three Ludwig and one Fick during repeated injection of ether into the
jugular vein in doses of first 20m., then 40m., and 60m., and finally 120m. One
injection of 60m. was also made into the thigh subcutaneously. When the
pulse was no longer perceptible, a. needle was thrust into the chest, but did not
reach the heart, and consequently did not move. The dog was still gasping
occasionally until the thorax was opened at 9h. 12m., when the heart was
found to have ceased beating, but rhythmical waves in the heart-wall occurred
until 9h. 24m., although the heart had been removed from the body and cut
open. Temperature after death 98 F. Post-mortem—Large clot in left ven-
t r i c l e . Ri g h t s i d e f u l l o f c l o t s .
Obervations .
H. M. S.
A. 8 13 30.—Ether 20 minims injected into jugular vein ; no effect.
B. 8 18 20.—Repeat injection of 20 minims of ether ; this injection
was followed by slight fall of blood-pressure.
C. 8 19 50.—Another 20 minims of ether injected into the jugular
vein. The fall of blood-pressure again occurred to
a greater extent.
D. 8 24 10.—Repeat ether injection. A still further fall of pressure
is noticeable and the recovery from this fall was
slow.
E. 8 27 20.—Forty minims of ether injected into the jugular vein.
A very rapid and deep fall of blood-pressure took
67
place and the pulse tracing disappeared (vide Fick 4). During recovery
at 8h. 32m. 0s. and 8h. 35m. 0s. the blood-pressure twice rose and fell
again in a remarkable manner without any apparent cause. (Compare
with Experiment 117, Observation G at 9h. 23m, 50s. to 9h. 25m. 15s).
The condition of respiration was not recorded at these times.
F. 8h. 40m. 0s.—Repeat injection of 40 minims of ether into
jugular. During recovery at 8h. 47m. 40s. a drachm of ether was injected
subcutaneously into the thigh. Recovery was arrested and a slight fall of
pressure took place ; but. no marked effects were produced.
G. 8h. 50m. 20s.—Injection of 60 minims of ether into jugular vein.
This was followed by rapid fall of pressure and complete loss of pulse
tracing, and the respiration stopped at. 8h. 53m. 0s. The pupils were
widely dilated.The animal began gasping at. 8h. 54m. 40s. and recovery
gradually took place, but the blood-pressure was not fully restored.
H.
9h. 7m. 40s.—Repeat injection of ether into jugular vein. This
time 120 minims were injected. The pressure rapidly fell again and the
respiration stopped for 20 seconds, after the injection was concluded. A
few gasps took place at 9h. 10m, 0s. ; the thorax was opened at 9h. 12m.
0 s . a n d r h y t h m i c a l . w a v e - l i k e m o v e m e n t s w e r e o b s e r v e d i n t h e v e n t r i c u l a r
walls of the heart, which continued until 9h. 24m. 0s. after the heart had
been removed from the Large
body. Large round clots were found in the left
ventrical extending into the aorta ; and the right side was full of clot.
Experiment 77 shows that, the effect of ether is precisely the same as that
of chloroform, only less intense. Like chloroform, ether, when efficiently
given, produces first, narcosis, then stoppage of the respiration and then death.
All the observations in the experiment show that every time ether was
injected into the blood, a fall of blood-pressure was produced ; and yet it is
the practice now-a-days to inject, ether subeutaneously when chloroform
poisoning occurs. It would be just as sensible to inject chloroform sub-
cutaneously in cases of poisoning from ether. Cases have even been recorded
recently where ether has been injected subcutaneously in ether poisoning.
This manifestly dangerous and unsound principle of treatment arises from
the fact that ether is regarded as a safe stimulant. whereas it merely quickens
the heart's beats. Experiment 77 shows that it is not a reliable stimulant
under any circumstances.
68
November 12th.—No. 78.
Monkey (Macacus). Weight 10½ lbs. Temperature of the room 21 Cent.
Into chloroform box at 10h. 4m. 30s. On to table at 10h. 9m. 23s. and kept
quiet with chloroform. Temperature in rectum 98. F. Artery ligatured at
10h. 34m. 50s. Loops under both vagi. Connection made with manometer at
10h, 46m. 30s. Two Ludwig and one Fick tracing.
H.
M. S,
Ob
s e v c a t i o n s .
A. 10 49 0.—Ordinary chloroform administration.
B.
......
Violent struggling with great irregularity of blood-
pressure.
C. 10 54 20.—Dropping chloroform into nostril ; effect of struggling
again shown.
D. 10 5 5 5 20.—Pushing chloroform until respiration stopped.
E. 11 6 20. Mechanical irritation of the right vagus.
F. 11 7
O. —El e c t r i c a l i r r i t a t i o n o f t h e e n t i r e r i g h t v a g u s , c o i l s
10 cent. distant (Fick 8).
G. 11 10 50.—Ligature of the right vagus.
H. 16 26 35.—Division of the same.
I,
11 29 40.—Irritation of the peripheral end of the right vagus, coil
at 10 (Ludwig tracing.).
.J. 11 31 0.—The same, only coil at 5 (Fick 9).
K. 11 33
0 . —I n j e c t i o n o f a t r o pi n e i n t o t h e p e r i t o n e a l c a v i t y .
L. 11 39 40. Irritation of the peripheral right vagus again, coil
5 (Fick 11).
M. 11 45 30.—The same, only coil 0.
N.B.—The effect upon the blood-pressure of pushing chloroform was not
nearly so great as in previous experiments. though the animal was very readily
put "under"
Hopeless clotting stopped the manometer at. 11h. 56m. 20s., and the monkey
was given chloroform finally with the view of killing it. Respiration stopped
at 12h. 4m. 40s. ; pulse perceptible until. 12h. (6m. 30s. Heart flag-moving
until 12h. 9m. 55s. Thorax opened and heart still beating rhythmically at 12h,
11m. 35s., a little blood passing into the aorta at each beat. The contractions
became partial and ineffective at 12h. 18m. 40s., but were re-established by
compressing the septum and continued until 12h. 28m. Irregular flickering
continued even after this for some minutes. Temperature 98 F. in the rectum.
69
November 12th.—No. 79.
Good-sized pariah, weight 33 lbs., that has had two doses of phosphorus
— o n e y e s t e r d a y , t h e o t h e r t o - d a y , e a c h 1 - 1 6 t h o f a b o x o f J a m e s b e e t l e p a s t e .
Into chloroform box at 2h. 9m. 34s. Fallen down 2h. 23m. 39s. Placed on the
table at 2h. 24m. 26s. Respiration stopped at 2h. 24m. 45s. Artificial respira-
tion until 2h. 27m. 39s. Artery ligatured and canula inserted at 2h. 36m. 13s.
Temperature in the rectum 100 F. Connection made with the manometer at
2h. 39m. 30s. Two Ludwig and one Fick tracing.
H. M. s.
Observations
A. 2 41 50. —Change to the vertical position of the body.
B. 2 43 10. —Chloroform administration while in the vertical position.
C. 2 44 45. —Ammonia inhalation do.
D. 2 46 40.—Squirting chloroform into the nose do.
E. 2 49 40.—Evulsion of the nails do.
F. 2 50 55. -Extraction of teeth do.
G. 2 52 55.—Violent slap with open hand on abdomen do.
H. 2 54 30. —Restoration to the recumbent position On the table.
I. 2 56 20.—Inversion of the body so that the dog was com-
pletely head downwards and again lowering to the
recumbent position.
J. 2 57 40.—Chloroform administration in the ordinary position.
K. 3 1 0.— Attempts to pass grooved staff and Thompson's dilators
into the bladder.
L. 3 15 5.— slitting prepuce.
M. 3 17 20.—Pushing chloroform carelessly until after respiration
had ceased.
Temperature after death 99 F. The organs did not appear to be fatty
.
November 13th.—No. 80.
Large monkey (Macacus), 21 lbs., caught in the hospital compound. Into
chloroform box at 3h. 31m. 38s. On the table and kept quiet with chloroform
3h. 37m. 40s. Temperature 100·2 F. Canula inserted into left carotid. Loop
under both vagi. Connection made with manometers at 2h. 39m. 30s.
70
Two Ludwig and two Fick tracings.
H. M. S.
Observations.
A. 4 7 40.—Ordinary chloroform administration. The effect of
struggling is well shown.
B. 4 11 0. —I r r i t at i on of r i ght vagus, ent i r e, coi l s 8 1/ 2 cent , di st ant
(Fick 4).
C. 4 14 10.—Irritation of left vagus, entire, 8 1/2 coil (Fick 5).
D. 4 14 50.—Chloroform again.
E. 4 17 45.—Injection of 1/5th grain atropine into peritoneal cavity.
F. 4 19 30.—Irritation of right vagus, coil 8 1/2 again (Fick 6).
G. 4 20 30.—Irritation of entire left vagus, coil 0 (Fick 7).
H. 4 22 30.—Pushing chloroform until respiration stopped com-
pletely, and restoration by artificial respiration.
The effect of struggling is well brought out in this
observation.
(Manometer tracing was interrupted at 4h. 33m. to
divide the left splanchnic nerve and started afresh
at 4h. 49m, 50s. after cutting the left splanchnic
nerve which did not appear to effect pressure much.)
I. 4 50 40.—Administration of chloroform for a short time.
J. 4 53 0.—Evulsion of nails.
K. 4 56 30.—Squeezing and afterwards smashing the testicles.
L. 4 58 20.—Pushing chloroform.
M. 4 59 0.—Thrusting needle into the heart and death.
Slow gasping movements of the chest continued after the heart had ceased
to beat. Temperature after death 98.2 F. Post-mortem—There was very little
hæmorrhage into the abdomen. The left splanchnic divided, right intact. No
clot in heart.
November 13th.—No. 81.
Medium-sized pariah dog, weight 30 lbs., which has been dosed with phos
-phorus for 2 days. 1-16th of a box of paste each day. Into chloroform box at 7h.
50m. 30s. Fallen down at 8h. lm, Placed on the table at 8h. 4m. 20s. Carotid
ligatured at 8h. 14m. 10s. Canula inserted at 8h. 19m 30s. Temperature