NationalLibraryOfScotland/medical-history-of-british-india huggingface dataset:
71
100.4 F. in the rectum. Connection made with manometers at 8h, 25m. 10s.
Loops under both vagi. Two Ludwig and one Fick tracing.
H .M. S.
Observations.
A. 8 28 30.—Application of bicarbonate of soda to the entire
right vagus.
B. 8 30 35.—Change to the vertical position and restoration to the
recumbent again.
C. 8 33 20.—Chloroform administration.
D. 8 37 10.—Blow on testicles.
E. 8 41 0.—Pushing chloroform with struggling until respiration
ceased (vide Fick. 5 and 6).
F. 8 42 10.—Artificial respiration.
G. 8 47 30.—Injection of 1/5 th grain atropine into the peritoneum
H.
8 53 10.—Irritation of right entire vagus, coil at 0.
I. 8 56 0.—The same ( vide Fick. 9).
J. 8 57 30.—Pushing chloroform with violent struggling.
Fall of pressure very rapid, and the dog died in spite of artificial respiration.
A clot in the vessels interrupted the tracing before the heart stopped. Tempera-
ture after death 97.4 F. Post-mortem-Organs not particularly fatty.
November 13th.—No. 82.
Good-sized monkey (Macacus). Weight 15 lbs. Temperature of the
room 20.5 Cent. Into chloroform box at 10h. 57m. 18s. Fallen down at 10h.
4m. 17s. On the table at 10h. Gm. 52s. and kept quiet with chloroform.
Artery ligatured at 10h. 35m. 53s. Canula inserted at 10h. 39m. 30s. Temper-
ature 99.2 F. in the rectum. Connection made with manometers at 10h 47m.
50s. Two Ludwig and one Fick tracing.
H . M .
s
O b s e r v a t i o n s .
A. 10 53 30.—Chloroform administration on a cap in the ordinary
way; violent struggling.
B. 10 58 10.—Pushing chloroform until respiration stopped; re-
covery without artificial respiration.
C. 11 10 20.—Division of both vagi.
D. 11 19 10.—Pushing chloroform until death resulted.
Temperature after death 99.4 F.
November 13th.—No. 83.
Medium-sized monkey (Macacus). Weight 12 lbs. Temperature of the
room 23 Cent. Into chloroform box at 2h. 21m. 33s. Fallen down at 2h. 30m.
15s. Placed on table at 2h. 32m. 10s. Carotid ligatured at 2h. 39m. 35s. and
canula inserted. Temperature in the rectum 103.2 F. Kept quiet with chloro-
form until connection made with manometers at 2h. 46m. 15s. Three Ludwig
and one Fick tracing.
Observations.
H. M. S.
A. 2 47 0.—Gradual coming out of chloroform.
B. 2 49 0.—Ordinary chloroform administration with struggling,
showing great irregularity of the blood-pressure.
C. 2 52 0.—Change of position to the vertical, during which
—
D.
2 53 0.—Extraction of teeth.
E. 2 55 20.—More chloroform and struggling at intervals.
F. 2 58 30.—Restoration to recumbent position.
G.
3 5 0.—Exposure of the ulna nerve at the elbow.
H.
3 7 0.—Tugging at the ulna nerve
.
I.
3 8 20.—Incision into abdomen over the stomach.
J.
3 16 0.—Ligature of a glass tube into that organ ; stitching
of the abdominal wound.
K.
3 19 20.—Inflation of stomach with air and suddenly allow-
ing the air to escape.
L.
3 25 0.—Re-opening the wound and re-adjusting the stomach
tube and re-stitching the abdominal wound.
M.
3 42 40.—Injection of hot water into stomach.
N.
4 0 0.—Injection of one-twelfth grain apomorphine into peri-
O. P.
4 2 30.—Artiticial respiration at times, the respiratio
Q.
4 9 40.—Iced water into stomach ;running out through the
nose.
73
Experiment interrupted by hopeless clotting at 4h. 12m. Stopped breath-
ing at 4h. 17m. 40s. The heart-needle stopped moving a few seconds before
the thorax was opened and the heart was found to be quite still. Temperature
after death 97.8 F.
November 14th.—No. 84.
Temperature of room 19 . 75 Cent. Medium-sized, well-nourished pariah
dog, weight 35 1/4 lbs., who has had daily doses of phosphorus for three days.
Chloroform commenced in box at 7h. 37m. Fallen down at 7h. 42m. On table
at 7h. 44m. 45s. Artery ligatured at 8h. 52m. and canula inserted. Tempera-
ture in the rectum 100.8 F. Connection made with manometers at 8h. 10m.
30s. Two Ludwig and one Fick tracing.
H. M. S . Ob s e r v a t i o n s .
A. 8 13 20.—Division of rectus muscle of the eye-ball.
B. 8 16 20.—Blow on the testicle.
C. 8 24 0.—Chloroform administration repeatedly, often accom-
panied by struggling.
D. 8 24 40.—Evulsion of nails.
E. 8 25 39.—Snipping anus.
F. 8 27 0.—Pushing chloroform until respiration ceased.
G. 8 29 40.—Artificial respiration.
H. 8 41 0. —Exposure, l i gat ure, and di vi si on bet ween l i gat ures of
both vagi.
I. 8 45 30. —Pushing chloroform until respiration ceased fatal
result (vide Fick 8).
From the character of Fick reading 8 and the Ludwig tracing just
before, it is doubtful if the vagi were really divided. Temperature after death 97 F.
In this experiment the absence of any effects from the operations which
are usually said to lie dangerous under chloroform is well brought out also the
rapid and irregular falls of the blood-pressure when the animal struggles
and breathes irregularly during the inhalation of the anæsthetic.
November 14th.—No. 85.
Temperature of the room 21 Cent. Medium-sized dog, weight 30 1/4 lbs.,
that has had phosphorus daily for 3 days, 1-16th of a box. Into chloroform
10
74
box at 9h. 42m. Fallen down at 9h. 45m. 10s. Placed on the table at 9h. 46m.
45s., after which its breathing was noticed to have stopped. Artificial respira-
tion was commenced at once, but failed to bring him round, although there
was a pulse some time after it commenced.
This is a case where a weak sick animal was left in the chloroform box
too long and its respiration neglected while it was being transferred to the
table.
November 14th.—No. 86.
Monkey (medium-sized Macacus). Weight 11 lbs. Into chloroform box
at 10h. 27m. 22s. Fallen down at 10h. 13m. 15s. Placed on the table and
kept quiet with chloroform. Carotid ligatured at 10h. 33m. 40s. Canula in-
serted at 10h. 39m. 30s. Temperature in the rectum 101 F. Connection made
with the manometers at 10h. 44m. Three Ludwig and one Fick tracing.
H . M . S .
A. 10 45 20.—Small incision into abdomen.
B. 10 47 10.—Administration of chloroform : struggling, and irregu-
larity of the blood-pressure.
C. 10 49 50.—Injection of 1-12th grain apomorphine into abdominal
cavity. (The animal then lay almost perfectly
quiet without more chloroform for almost an hour,
during which he was given another dose of apo-
morphine 1.-12th grain.)
D. 11 43 30.—Pushing chloroform, with struggling, until respiration
ceased recovery with artificial respiration.
E. 11 46 0.—Thrusting a needle into the chest but not into the heart.
F.
11 51 30.—Effect of letting the tongue drop.
G.
11 54 30.—Repetition of D and E, and thrusting a needle into the
heart.
H.
12 19 0.— Injection of atropine, 1/4 grain, in abdomen, and finally
pushing chloroform until death resulted.
Thorax opened at 12h. 26m, respiration having stopped, but afterwards
there wore again regular movements of the diaphragm, which continued off and
on until 12h. 23m. 50s., when they finally stopped. The tracing was stopped
75
by hopeless clotting at 12h. 31m. Heart stopped very gradually, but not
finally until 12h. 37m. Temperature after death 95.4 F.
November 14th.—No. 87.
Mr. Ulett's bull dog, weight 31 lbs., suffering from tumours in the inguinal
region. Into chloroform box at 2h. 14m. 10s. Fallen down at 2h. 23m. 10s.
Placed on the table and kept quiet with chloroform. Temperature in the
rectum 102 F. Loops under both vagi. Artery ligatured at 2h. 34m. 30s.
Cannla inserted 2h. 40m. 20s. Connection made with manometers at 2h. 43m.
40s. One Ludwig and one Fick tracing.
H. M. S.
Observations.
A. 2 46 30.—Ordinary chloroform administration.
B. 2 48 0.—Irritation of entire right vagus with coils at 5 centi-
metre distance.
C. 2 53 50.—Pushing chloroform, with accidental compression of the
neck by a strap (vide Fick 3). The same slowing
of the pulse was produced as is observed when
t h e v a g u s i s i r r i t a t e d .
D.
3 0 0. —Pushi ng chl or of or m unt i l r espi r at i on compl et el y
ceased.
Failure to restore the animal by artificial respiration.
Temperature after death 101.2 F.
November 14th.—No. 88.
Temperature of room 24 Cent. Medium-sized pariah dog. Weight 30 lbs.
Into chloroform box at 3h. 22m. 26s. Fallen down at 3h. 24m. 45s. Placed on
the table at 3h. 26m. 25s. Artery ligatured at 3h. 37m. Temperature in the rec-
tum 100.2 F. Canula inserted at 3h. 40m, 53s. Connection made with manometers
at 3h. 50m. 11s. Loops under both vagi. One Ludwig and one Fick tracin
g .
H . M . S . O b s e r v a t i o n s .
A. 3 51 0.—Pushing chloroform accompanied by struggling
u n t i l
respiration stopped. (The trace is spoilt by the
drum not rotating for nearly a minute.) The fall of
pressure was extremely rapid and irregular. Fick
2 shows that when the respiration is stopped by
an over-dose of chloroform, a condition of pulse
similar to that caused by vagus stimulation may be
produced.
76
H . M . S .
B. 3 52 50.—Recovery with artificial respiration.
C . 3 5 9 2 0 . — P r e s s u r e o n a b d o m e n .
Pushing chloroform again until respiration stopp
e d .
D i v i s i o n o f b o t h v a g i w h i l e t h e a n i m a l w a s d e e p l y
under. Fick 5 shows that after division of the
D.4 1 0.— vagi the slowing of the pulse observed in stop-
page of the respiration in chloroform poisoning
did not occur.
E . 4 4 0 . — G r a d u a l f a l l o f p r e s s u r e a n d d e a t h i n s p i t e o f a r t i f i c i a l
respiration.
Temperature after death 98.4 F.
N o v e m b e r s 1 5 t h . — N o . 8 0 .
Temperature of the room 21 Cent. Unusually large brindled dog. Weight
38 lbs. Into chloroform box at 7h. 38m. Fallen clown at 7h. 46m. 20s.
Placed on the table 7h. 48m. 50s. Temperature in the rectum 99 .8 F.
Left carotid ligatured at 8h. 2m. 5s. Connection made with manometer at 8h.
6m. 30s. Four Ludwig and two Fick tracings.
Observations. H. M. S.
A. 8 10 45.—Chloroform administration with struggling (the excur-
sions of the marker had previously been unusually
great), and pushing the same until respiration
ceased.
B.
8 2 4 2 0 . — A r t i f i c i a l r e s p i r a t i o n a n d g r a d u a l r e c o v e r y .
C.
8 2 9 3 0 . — D i v i s i o n o f b o t h v a g i .
Administration of chloroform again until respiration
D. 8 38 10.—
ceased, and
Artificial respiration as before.
E. 8 47 40.—Compression of the chest and administration of chloro-
form on a saturated sponge at the moment the chest
was released.
F. 8 51 0.—Pressure on abdomen.
77
H . M . S .
G. 8 51 0.—Pushing chloroform again until respiration stopped :
and artificial respiration as before.
H. 8 54 40.—Tracheotomy and insertion of a large glass tube into
the trachea.
I. 8 59 0.—Repetition of F by stopping the tracheal tube when the
chest was in the expiratory position, holding chloro-
form in front of the tube, and then suddenly opening
it.
J. 9 5 40.—Continued administration of chloroform by holding a
sponge or towel before the end of the tube.
K.
9 7 15. —Cl os i ng t he t r a c he a l t ube s o a s t o c a us e a s phyxi a .
L. 9 12 25.—Administration of chloroform by Junker's tube intro-
duced into the tracheal. tube, which remained open,
and pushing it again ulntil respirations stopped, and
artificial respiration as before.
M. 9 26 10.—Administration of ether in the same way ; but this
failed to keep the animal thoroughly under. After
chloroform had been again given the manometer
was disconnected in order to divide the medulla
oblongata.
All attempts to reconnect after its division failed on account of clot in the
vessel, and the heart ceased beating at 11h. Temperature at 11h. 5m., 96 F. in
the rectum.
In this experiment slowing of the pulse, in Observations A and B,
which occurs when the respiration fails from over-dosing with chloroform
is shown (vide Fick 6 and 9). This effect. is not. produced after division of the
vagi (vide
Fick 10 and 11). The effect of asphyxia in lowering the blood-
pressure is also seen in the Ludwig tracing at 9h. 7m. 20s. and 9h. 9m. 40s.
The difference in intensity between diluted chloroform and diluted etker,
administered in precisely the same way, is brougkt out in Observations
L and M.
November 15th.—No. 90.
Medium-sized strong pariah, given 1 grain of morphine hypodermically at
2h. 24m. 10s. Temperature of the room 241/2, Cent. Salivated a good deal at
78
2h. 33m. and afterwards went to sleep. At 4h. 15m. he was still irritable and
unfit for experiment.
November 14th.—No. 91.
Large pariah dog, 38 lbs. Temperature of the room 24.5 Cent. Chloroform
given at 2h. 34m. 45s. Fallen down at 2h. 41m. 30s. On the table at 2h. 43m.
15s. and kept quiet with chloroform. Temperature in the rectum 100 . 4 F.
Right jugular vein ligatured at 2h. 41m. Canula into carotid at 2h. 48m. 5s.
Connection made with manometers at 3h. 1m. 30s. The pressure in the mano-
meter had been arranged a little too high before commencing, so that some
bicarbonate of soda must have been shot into the vessel. No convulsions
occurred. Three Ludwig and one Fick tracing.
Observations.
H . M .
S.
A. 3 6 0.—A long period in which the dog was left without chloro-
form and occasionally struggled.
B. 3 34 20.-Injection at different times of 4 closes of chloroform.
20 minims each (except in one instance when about
5 minims or possibly more was spilled), into the
jugular vein. After the 4th close the clog died,
the heart stopping at 4k. 13m.. Temperature in
rectum at death 97 . 2 F. Post-mortem.—No clots
in heart.
November 18th.—No. 92.
Temperature of the room 23 Cent. Large-sized pariah dog. Weight
33½. lbs. rather thin. Into chloroform box at 7h. 24m. 43s. Fallen down at
7h. 28m. 43s. On the table at 7h. 29m. 37s. Artery ligatured at 7h. 41m. 8s.
and cariula inserted. Temperature in the rectum at 7h. 42m. 30s., 100.6 F.
Jugular vein tied at 7h. 51m. 47s. Connection made with the manometers at
7h. 58m. 20s. Three Ludwig and one Fick tracing during repeated injections
of chloroform into jugular vein. Nine doses were given in the course of an
hour, and death ensued very gradually. Temperature after death 97 F.
Post-mortem—After the chest was opened 4 or 6 regular movements of opening
and shutting the jaws coincident with rhythmical contractions of the diaphragm
occurred. The heart was quite still in all its cavities. There were no clots
in the heart. No sign of the needle in the heart.
79
Observations.
H . M .
S .
A. 8 0 15.—Twenty minims of pure chloroform injected into the
jugular vein.
B. 8 2 40.—Repeat.
C. 8 3 50.—Repeat.
D. 8 5 55.—Repeat. This injection was followed by lowering of
the blood-pressure, which never rose again. The
injection of twenty minims of chloroform was repeat-
ed at 8h. 13m. 20s. ; 8h. 14m. 10s. ; 8h. 40m. 30s.
; 8 h . 4 3 m . 2 0 s . ; a n d 8 h . 4 6 m . 1 0 s . I t s e e m s c l e a r f r o m
e x p e r i m e n t s . N o . 9 2 t h a t d i r e c t a c t i o n o f c h l o r o f o r m
upon the heart substance is not the cause of the fall
of blood-pressure that occurs when it is inhaled.
Repeated injections of twenty minims of pure chloro-
form were made into the jugular vein, and the effect
was not to paralyse the heart, but to produce
narcosis with a gradual fall of pressure exactly as
if the chloroform had been inhaled. Compare
with Observation D of Experiment No. 64.
November 18th.—No. 93.
Temperature of the room 24 Cent. Large pariah dog. Weight 33¼ lbs.
Into chloroform box at 9h. 59m. Fallen down at 10h. 5m. 25s. On the table at
1 0 h . 8 m. 2 7 s . a n d k e p t q u i e t wi t h c h l o r o f o r m. Ar t e r y l i g a t u r e d a t 8 h . 2 0 m.
50s. Canula inserted at 8h. 22m. 22s. Temperature in rectum 99.8 F. Con-
nection made with manometer 10h. 28m. 45s. Two Ludwig and one Fick
tracing during injection of ether into the jugular vein with at the same time
injection of solution of hydrochloric acid (0.8 per cent.) in normal saline solu-
tion into the femoral vein. Notice also effect of thrusting needle into heart.
Temperature 101.2 F. after death. Post-mortem-Heart very much distended.
Right ventricle full of clot. Left free. Superior and inferior venal cava and
pulmonary artery filled with clot
.
H. M. S.
Observations.
A. 10 30 10.—Ether on an ordinary cap until 10h. 39m. 40s. The
animal was quiescent, but complete narcosis was
not produced. A great deal of frothy fluid accumu-
lated in the trachea.
80
H . M . S .
B. 10 40 20.—Twenty minims of ether injected into the jugular
vein. The injection was repeated at 10h. 41m. 10s.
and 10h. 42m. 15s. and each time the blood-pressure
fell and rose again in 40 or 50 seconds. At
1 0 h . 4 7 m. 1 0 s . a n d a g a i n a t 1 0 h . 5 2 m. 3 0 s . f o r t y
minims of ether were injected. There was on each
of these occasions a very rapid and prolonged fall
of blood-pressure and a slow weak pulse with
very diffucult recovery.
C. 11 1 30.—Injection of sixty minims of ether into the jugular
vein. The fall of blood-pressure was immediate
and rapid, and the pulse tracing became almost
imperceptible (vide Fick 6 and 7). The pressure
remained low until 11h. 5m. 20s., when slight
recovery took place (vide the Ludwig tracing at
1 1 h . 5 m . 0 s . ) A t 1 1 h . 6 m . 0 s . s i x t y m o r e m i n i m s o f
ether were injected into the jugular vein and this
injection caused stoppage of the respiration and
death. Post-mortem gasps occurred as in Experi-
ment No. 92. The heart was found full of
venous clot.
November 18th.—No. 94.
The dog in No. 90 having escaped from the cage, another dog was given
2 grains of morphia at 8-20 a.m. At 10 o'clock he was still irritable and unfit
for experiment, for, although sleepy and at first sight apparently insensitive, he
could be easily aroused by even painless stimuli and then ran about in an ex-
cited wild way .
November 18th.—No. 95.
Temperature of the room 251/2 Cent. Monkey (medium-sized Macacus).
Held down on table and given ether on a cap at 2h. 50m. 45s., his temperature
in rectum being 102.4 F. at that time. Ether stopped at 2h. 51m., the animal
being quite quiet, though cornea not insensitive. Respiration chiefly abdomi-
nal, 68 per minute. Artery ligatured at 3h. 7m. 45s.. and loop placed under
left vagus. Canula inserted into artery at 3h. 11m. 33s. Left jugular acci-
d e n t a l l y c u t ; s o l i g a t u r e d . L o o p u n d e r r i g h t v a g u s a n d r i g h t c a r o t i d . E t h e r
81
given now and again during above proceedings. Connection made with mano-
meter at 3h. 26m. 50s. Two Ludwig and three Fick tracings.
H. M. S. Observations.
A. 3 26 50.—The quiescent condition, not anæsthesia, produced
by ether.
B. 3 28 10.—Irritation of the nostril by chloroform, and
C.3 2915.—Ammonia.
D. 3 36 5.—Clamping of the right carotid so as to cut off both
carotids.
E. 3 35 0.—Extraction of teeth with the key. (vide Fick reading
marked "6" on the Fick tracing, but noted as
" 5 " on the Ludwig tracing.)
F. 3 50 10.—Exposure and irritation of the sciatic nerve.
G. 3 53 30.—Irritation of the entire right vagus coil 10 producing
coughing (Fick 8).
H.3 54 40.—Irritation of the entire left vagus coil 10 (Fick 9).
I.3 55 50.—Irritation of the entire right vagus coil 5 (Fick. 10).
(The effect of irritation of the right was less than
that of the left vagus).
J. 4 0 30. —Li gat ure and di vi si on of t he ri ght vagus (Fi ck 11).
K. 4 14 55. —I r r i t at i on of cent r al r i ght vagus coi l 5 ( Fi ck 14) .
L. 4 17 15. —Irri t at i on of peri pheral ri ght vagus coi l 5 (Fi ck 15).
M. 4 20 0. —Li gat ur e and di vi s i on ( Fi ck 16) of l ef t s , vagus .
N. 4 21 30. —I r r i t at i on of cent r al l ef t vagus coi l 5 ( Fi ck 17) .
O. 4 25 0. —Irri t at i on of peri pheral l eft vagus coi l 5 on t wo occa-
sions (Fick 18, 19), but doubtful if the nerve was
really irritated in the first.
P.4 37 0.—Pushing ether on cap closely applied over muzzle
until death ensued.
Manometer stopped on account of clot at 4h. 45m. Needle into heart
;hardly moving. Thorax opened 4h. 46m. 20s. Heart still.
No clots in the .heart cavities. Temperature at 4h. 35m. 40s. in the
rectum 100 . 2 F.
11
82
November 19th.—No. 96.
Temperature of the room 23 Cent. Medium-sized female monkey
(Macacus). Weight 111/3 lbs. Into chloroform box at 9h. 23m. Fell down at
9h. 31m. On the table at 9h. 33m. Temperature in rectum 100.4 F. Artery
ligatured at 9h. 52m. 50s. Canula inserted at 9h. 58m. Connection made with.
manometer at 10h. 6m. 40s. Two Ludwig and one Fick tracing.
H . M . S .
0bservations.
A. 10 8 20.—Ordinary chloroforms administration,
B. 10 16 40.—Bandaging the abdomen.
C. 10 21 0.—Bandaging the lower chest with plaster of Paris.
Death ensued from asphyxia and in spite of artificial respiration after re-
moval of the bandage. Post-mortem—Heart cavities firmly contracted after
death, and lungs engorged. Trachea full of froth. Temperature at end of
Experiment 96.2 F. in rectum.
November 19th.—No.97 ,
Medium-sized female monkey. Weight 93/4 lbs. Temperature of the
room 231/2 Cent. Into chloroform box at 10h. 50m. Fallen down at 10h, 58m.
30s., and placed on the table. Temperature in rectum 102.4 F. Artery liga-
tured at 11h. 11m. 10s., and canuha inserted. Connection made with mano-
meters at 11h. 21m. 50s, One Ludwig and one Fick tracing.
H. M. S.
Observations.
A. 11 26 30.—Struggling.
B. 11 27 30.—Application of a plaster of Paris bandage to the chest
to imitate stays, and of
C. 11 32 0.—A tight broad tape round the lower part of the abdo-
men to imitate the eftct of petticoats.
D. 11 33 O.—Pushing chloroform until respiration stopped.
Death ensued although the bandages were quickly removed and in spite
of artificial respiration. Post-mortem-Blood, arterial, in left side of heart.
Temperatureafter death 102.4 F.
November 19th.—No. 98.
Small monkey fastened on to the rabbit board at 3h. 14m. 30s. A pin
placed in the heart and connected by a thread with a time-marker waiting on a
83
quick revolving drum (the same as is used for the Fick manometer). The
experiment was imperfect, but a few readings are preserved showing effect of
placing ammonia before the nose.
November 20th.—No. 99.
Small rabbit on to rabbit board at 7h. 30m. with a needle in its heart attach-
ed by a long thread to a time-marker. The trace shows the effect of holding
ammonia before the nose.
November 20th.—No. 100.
A monkey arranged in the same way. One trace showing the absence
of any effect when ammonia is held before the nose, corresponding to that which
occurs in the rabbit.
November 20th.—No. 101.
Small rabbit arranged as above and chloroform held before his nose. One
tracing incorporated with the first tracing of 102.
November 20th.—No. 102.
Another rabbit in the same way. Chloroform given as before. Two
tracings.
November 20th.—No. 103.
Large monkey. Weight 161/4 lbs. Temperature of the room 24 Cent.
Into chloroform box at 9h. 8m. 44s. Fallen down at 9h. 15m. 5s. Placed on
the table at 9h. 19m. Temperature in rectum 101.8 F. Artery ligatured at, 9h.
37m. 10s. Canula inserted at 9h. 40m. 30s. Connection with manometer at
10h. 3m. 15s. Four Ludwig tracings and three Fick.
Observations.
H . M . S
A. 10 6 20.—Mechanical irritation of the left vagus.
B. 10 7 30. —St ruggl i ng.
C. 10 8 20.—Irritation of the entire right vagus, coils 10 Cent.
apart (Fick 4).
D. 10 14 55.—Irritation of the entire left vagus (Fick 5).
E. 10 17 30.—Irritation of the left vagus and pushing chloroform at
the same time.