xxxiv
Kidneys.—The right weighs 1 lb. 10½ ozs. and left 1 lb. 11½ ozs. The capsules strip
easily. There are no petechiæ on the surface of the organs and on section, the tissues
appear perfectly healthy.
Small Intestines healthy.
Large Intestines. Cæcum and Colon contain 16 specimens in all of the Strongylus
armatus.
Nasal fossce.—The mucous membrane covering the turbinated bones presents a dark-red
or almost black appearance, but the membrane is only a little, if at all, increased in thickness-
Brain.—The dura-mater is healthy in appearance. There are some small patches light-
red in colour merely of congestion with no effusion of blood under the visceral layer of the
arachnoid.
The Lateral Ventricles are normal in size and do not contain any appreciable amount of
fluid.
Spinal Cord normal in appearance.
Memories.—This animal belonged to the Bombay Tramway Company and the case was
recognized as one of Surra on the morning of the 23rd September 1892, on the discovery of
the hæmatozoon in the blood. The mare was taken into the Laboratory Hospital on
September 24th when she appeared to be in good condition, but showed unmistakable
symptoms of the disease, and on microscopical examination of the blood hæmatozoa were
found to be numerous in it.
It was decided in this case to again try the effect of the mixed Cinchona Alkaloids and
Arsenic on the hæmatozoon, as it had shown promise of efficacy in that of Horse No. LXV
in which case, after a short exhibition of the drags, the hæmatozoon was kept in subjection
for a period of 27 days. Consequently as a fresh trial was resolved upon, the animal was
first put upon small doses, beginning with one drachm of the Alkaloids and four grains of Arsenic
given in the form of the Liquor Arsenicalis. On the morning following the first dose, the
temperature was found to have fallen over a degree and the hæmatozoon was absent from
the blood, the temperature remained low and the organism absent, for the next five days,
during which period two doses of the medicine were administered daily. On reference to
the chart, it will be seen that on the 9th day of the disease the hæmatozoon again appeared in
the blood, consequently on the 10th the doses of Alkaloids and Arsenic were increased to one
and a half drachms and five grains respectively; these were continued for a period of eight
days, during which time the hæmatozoon varied in numbers between few and very numerous.
On the 18th day of the disease a further increase in the doses was agreed upon and
during the next four days they were put up to Alkaloids two and a half drachms and
Arsenic grs. vi. and for the latter half of this period the organism was absent from the
blood, but re-appeared on the 22nd day and remained on the 23rd at few. On the former
date the Alkaloids were increased to drs. iii and the Arsenic to grs. viii and from the 23rd to
the 35th day of the disease, on which latter date the animal succumbed, the hæmatozoon
was entirely absent from the blood.
During the thirty-two days the animal was under treatment, three hundred and fifty-
five grains of Arsenic in the form of Liquor Arsenicalis and one hundred and fifty-four and a
half drachms of the mixed Cinchona Alkaloids were administered.
RECORDS OF URINE.
Animal, Moan Mare , No. LXXI. Date, September 24th, 1892. Disease
Surra, naturally acquired.
Date.
1892.
September 24th
25th.
29th.
October 4th.
8th.
9th.
11th.
12th.
14th.
19th.
21st.
23rd.
25th.
27th.
Quantity.
......
.....
...
......
.....
......
......
......
......
Colour.
Clear, yellowish-red ...
Do. ...
viscid, turbid greenish-
yellow.
Viscid, turbid yellow ...
Viscid, turbid greenish-
yellow.
Viscid, turbid orange...
Viscid, turbid yellowish-
brown.
Viscid, turbid brown ...
Viscid, turbid yellowish-
Viscid, turbid greenish-
orange.
Viscid, turbid greenish-
orange.
Viscid, turbid brownish-
yellow.
Viscid, turbid greenish-
yellow.
Turbid, viscid-orange...
Re-action.
Neutral
Alkaline
„
...
„ ...
„ ...
„ ...
„ ...
„ ...
„ ...
„
...
„
...
„ ...
„ ...
„ ...
Specific
Gravity.
1,029
1,029
1,046
1,028
1,038
1,030
1,010
1,042
1,034
1,010
1,039
1,012
1,030
1,030
Albumen.
1-17th ...
l-17th
...
A trace ...
l-20th
...
Trace ...
1-30th ...
A trace ...
„ Absent ...
„ ...
„ ...
„ ...
„ ...
A trace ...
Phosphates.
Nil
„ ...
„ ...
„ ...
„ ...
„ ...
„ ...
„ ...
„ ...
„ ...
„ ...
„ ...
„ ...
Remarks.
Carbonates and oxalates of cal-
cium crystals. No casts.
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