ccxlii
8th Dec—Temp. A.M.
9th
„
10th
„
11th.—Death at 3 A.M.
40.3°C.
40.1°C.
40°C.
P.M. 40.3°C.
„ 41.1.C.
„
40°C.
Hæmatozoa absent from the blood.
„
few in the blood.
„ „
AUTOPSY AT 12.30 P.M.
The body is poorly nourished; the under-surface of the abdomen is stained yellow with
urine pigment; there is swelling of the integument of the nose, mouth and eyes. Yellow
creamy pus exudes from both nostrils and the eye-lids are occluded. The œdema of ears so
noticeable during life had almost disappeared. On opening the chest, the heart and lungs
bulge forward.
The lungs present a normal pink colour on their inferior surface, but on
removing them from the thorax, the superior surfaces present numerous localized patches
of emphysema. On section there exudes from the lungs on pressure a frothy, slightly
blood-stained fluid.
Heart.—All the cavities of this organ are distended to their utmost, but there are no
endocardial extravasations.
Liver.—Appears healthy.
Spleen.—Small, tissue firm. On section, apparently healthy.
Kidneys.—Nothing pathological.
Stomach.—External appearance healthy, with the exception of the pyloric end of the
organ. The valve appears considerably increased in size and hard to the touch.
On section the mucous membrane is apparently healthy, but the wall of the organ is
found to be considerably increased in thickness.
Duodenum.— Distended to double its usual capacity from generation of gas. No
enlargement of mesenteric glands.
Bladder.—Greatly distended with urine.
Remarks.—This animal was inoculated with .3 c.c. of blood, containing numerous
hæmatozoa, from the horse.
The period of incubation occupied five days. The hæmatozoon was then found in the
general circulation. Subsequently on several occasions the organisms could not be found
in the blood of the general circulation, although it was present in large numbers in the
fluid from the seat of inoculation. The time which elapsed between the inoculation and
death was thirty-nine days. The chief pathological lesions found at the autopsy were,
the presence of localized emphysema of the lungs and the increase in thickness of the walls
of the stomach at the pyloric extremity.
No. II. RABBIT.
2nd November 1890.—Inoculated subcutaneously in the right ear with .3 c.c. of blood
from Horse No. II., in whose blood, hæmatozoa were very numerous. Temp. A.M. 39.6°C
Temp. P.M. 39.9°C.
3rd.—
4th
5th
6th
Temp. A.M. 39.7°C.
„ 39.5°C.
„ 39.6°C.
„
39.4°C.
P.M.
„
„
„
39.9°C.
39.8°C.
39.9°C.
39.9°C.
No hæmatozoa in the blood.
„ „
„ „
„ „
7th.—The inoculated ear presents numerous small mulberry petechiæ, somewhat light
in colour. There are no hæmatozoa in the blood. Temp. A.M. 39.8°C. Temp. P.M. 40.2°C.
8th.—Temp. A.M. 40°C. There are no hæmatozoa present in the blood. Temp. P.M.
40.5°C.
9th. — The serous exudation from the seat of inoculation contains swarms of hæmatozoa ;
60 counted in one field. The ear is swollen to three or four times its normal size. The
purple colour is still present over the whole œdematous portion. Temp. A.M. 40.2°C. The
animal is extremely lively. Four cover-glass specimens of blood, taken from the other ear,
were examined with great care, but no hæmatozoa were discovered therein. There are
however present in the blood, numerous small highly refractile bodies which appear to
possess more than a Brownian movement. Some of the red corpuscles are vacuolated and
lie individually separate, with no tendency to form rouleaux. Temp. P.M. 40.8°C.
10th.—The serous exudation taken from the seat of inoculation contains numerous Surra
hæmatozoa. The blood taken direct from a vessel presents no other features than the
presence of a few refractile bodies. There are no hæmatozoa in the blood. Temp. A.M.
40.6°C. P.M. 41.2°C.
11th.—The swelling and œdema at the seat of inoculation still persist and are dark in
colour. Temp. A.M. 40.8°C. Hæmatozoa few in the blood. Temp. P.M. 41.2°C.