32
An Urticarial eruption appeared forty-eight hours after the first appearance of
the hæmatozoon in the blood and persisted for twelve hours. The continued
type of fever accompanied by remissions appeared on the second day, and was
followed by an intermission on the fourteenth, and by death on the seventeenth
day of the disease. Extensive pathological lesions were found invading the Avails
of the heart externally and internally.
Horse No. XXXIV.—Was
inoculated subcutaneously on the 2nd August
1881, with l.0 c.c. of blood taken from the Internal Jugular Vein of Horse
No. XXXI. The latent period "was twelve days. The temperature remained
sub-normal until after the appearance of the hæmatozoon in the blood for the
first time. It then rose 2.7°C. in eighteen hours. The animal only survived the
appearance of the organism twenty-seven hours, death on August 15th. Exten
sive pathological lesions were found involving the heart and other organs
together with the presence of a considerable quantity of fluid in the lateral
ventricles of the brain.
Horse No. XXXVIII —Was subcutaneously inoculated on the 26th
August 1891, with l.0 c.c. of blood taken from the heart of Horse No. XL, nine
and half hours post mortem. The latent period occupied nine days. The rise
of temperture in this case was peculiar in that, although it followed for a few
days the usual zig-zag course, increasing 0.5˚C. per day, it was characterized by
a morning exacerbation and evening remission, until the sixth day of the disease,
when an apyrexial period occurred lasting four days. Between the ninth and
thirty-fifth days of the disease, alternate fever and fever-free periods existed, the
fever attaining a minimum in the morning or at midday and being generally
followed in the night by a sudden fall of from 2°C. to 3°C. and finally during the
last night days being again accompanied by fever of a remittent type, with ex
acerbations and remissions. This animal developed kidney complications charac
terized by the presence of albumen and epithelial casts in the urine and later by
granular and hyaline casts. The urine remained alkaline until seven days before
death, when it became respectively faintly alkaline, neutral, acid and finally
strongly acid. Death occurred on the 16th October 1891, Cheyne-Stokes respira
tion being present for a short time before it occurred. Extensive pathological
lesions were observed in the heart, with complete absence of any in the stomach,
and of parasites from the intestinal tract.
Horse No. XL.—Was subcutaneously inoculated at noon on 15th August
189], with 0.6 c.c. of blood taken from the Internal Jugular Vein of Horse
No. XXXIV, one and a quarter hours P.M. Sixty-eight hours later, an Urticarial
eruption broke out. It persisted for 74 hours and then commenced to fade after
the hæmatozoon appeared in the general circulation. The latent period occupied
six days. Decrease in size of the tumour at the seat of inoculation and the
simultaneous appearance of the organism in the blood. Temperature sub-normal
until the presence of the hæmatozoon, when it rose and followed the continued
type of fever with remissions until death on the 6th day.
Autopsy.—Patches of congestion involving the mucous membrane of the
villous portion of the stomach, also three small circular ulcers, undergoing the
process of healing and a female specimen of Ascaris megalocephala in the same
cavity, also lesions involving the heart, lungs, &c.
Horse No. XLI.—Was subcutaneously inoculated on 26th August 1891 with
l.0 c.c. of blood taken from the heart of Horse No. XL nine and a half hours
post mortem. On the following morning an eruption of Urticaria broke out and
persisted for thirty-six hours and then commenced to fade, i,e., five days previous
to the first appearance of the organism in the blood. The latent period occupied
seven days. The temperature remained sub-normal and normal the whole time,
varying between 35.3°C. and 37.3°C. The pathological lesions were slight.
Horse No. XLVI.—Vide Rat Surra, Vol. II.
Horse No. XLVIIL—Vide
Rat Surra, Vol. II.
Horse No. L.—Was inoculated subcutaneously on the 15th October 1891
with 2.0 c.c. of blood serum taken from the Internal Jugular Vein of Horse
No, XXXVIII, forty-five minutes post mortem. There was a gradual rise in the
temperature until the evening of the fifth day following inoculation and by the