20
temperature became normal on the 31st and remained at 37.2˚C. until the morn
ing of the 7th of November, when the temperature registered 39.4˚C. and the
hæmatozoon was discovered on microscopical examination of the blood. From
that date until the morning of the 24th November three marked periods of fever
occurred with irregular intermissions, the maximum temperature attained being
41°C. During a period of twenty-one days, which terminated in death, the
temperature oscillated between 39.4°C. and 36.5°C.
Albumen was found in the urine on the 27th day of the disease and per
sisted until December 4th, the result of a desquamative nephritis. For eleven
days previous to death, with one exception, when it was present as a mere
trace, albumen was absent.
Treatment.—This animal was (i) subjected to the action of Santonin, with
negative results ; (ii) the double Iodide of Potassium and Mercury, also with
negative results ; (iii) Arsenic for twenty-three days, during which time the
bæmatozoon was absent for seventeen days from the blood. The animal
succumbed on the sixty-third day of the disease.
Autopsy.—Body emaciated, a little oedema in the front of the sternum.
Thorax.—Each cavity contained between 20 and 30 ounces of fluid.
Lungs.—Both visceral pleurae were adherent to the parietal for a consider
able extent. There were also several extensive sub-pleural extravasations,
the anterior lobule and the anterior third of both organs were consolidated.
Pericardial sac contained ten ounces of an orange-coloured fluid. Heart was en
larged, the base was the seat of a considerable amount of yellow gelatinous
exudation. Right auricle healthy in appearance. Left auricle healthy in appear
ance. The right ventricle presented a few sub-endocardial extravasations. The
left ventricle presented an extraordinary appearance, the upper portion of the
cavity being almost black in colour, owing to the presence of extensive extrava
sations of dark coloured blood beneath the endocardial lining. One lying on the
inter-ventricular septum was 3.5"X l.5"and raised one inch above the surround
ing tissue. There were also numerous smaller extravasations dotted over the
lower half of the cavity. The abdominal cavity was free from fluid. The liver
was normal in size, presented old signs of perihepatitis, together with a few
calcareous nodules invading the tissues. Spleen normal in size. On section the
tissues presented a healthy appearance. Kidneys, pale, but presented a healthy
appearance. Stomach.—The cuticular portion normal, the mucous membrane
of the villous portion was healthy, but two large Spiroptera tumors involved
its substance. Small intestines healthy. Large intestines presented a patch of
congestion, but no ulceration. Rectum, two inches from the anal orifice, there was
an ulcer undergoing a reparative process which was situated upon a raised base.
Badder.—There were a few small, round extravasations of blood dotted over
the mucous membrane.
No. LXXVI.—A grey Australian gelding, No. 328, aged 11 years, had been
four years in the country. It was first noticed to be ill on 8th November 1892.
The Surra hæmatozoon was discovered in the blood on the 25th November.
There was fever of the continued type, accompanied by more or less marked
remissions and exacerbations from the 26th November to the evening of the 4th
December, after which the temperature gradually fell and during a further
period of thirty-one days, it never exceeded the healthy limits. The urine from
the first contained granular casts, and on thirty-eight days out of thirty-nine,
contained albumen, varying in amount from 1/40th to ⅓rd. Treatment.—For five
days this animal was subjected to a treatment consisting of large doses of Liq.
Potassæ ; but as this chemical appeared to have no effect but for evil on the
animal and none whatever on the hæmatozoon, Arsenic was substituted on the
eighth day with marked effect from the first, as the temperature and respirations
immediately commenced to fall, and the organism, after a short delay, disap
peared from the blood and remained so during a period of twenty-seven days.
Death occurred on the 4th January 1893.
Autopsy.—Body extremely emaciated, complete absence of subcutaneous
adipose tissue and œdema from the extremities and under-surface of the abdo
men. Thorax.—There was no fluid in the pleural cavities and there were no