liv
Lungs.—The surface of the right presents a variegated appearance; the general hue
is yellow. The anterior lobule is of a reddish-yellow colour and is the seat of emphysema.
Just behind this, and occupying the anterior portion of the organ, is a slightly raised patch
measuring 7" × 5" × 2.5", somewhat hard to the touch, over which the pleura is of a
yellowish colour, due to a thin layer of solid exudation lying between its under-surface and
the pulmonary tissue.
On section.—The tissues present a yellowish-red colour; those of the individual lobules
are consolidated and in some instances the latter are insulated by a thin layer of exudation.
On passing the hand over the pleural surfaces of the posterior portion of the oro-an several
small nodules can be felt varying in size from 1/4th to 7/12th of an inch in diameter. On sec-
tion they are found to consist of a central portion which has undergone caseation and are
surrounded by fibrous tissue ; whilst the remaining portion of the lung is well filled with
air, and the naked-eye appearances are healthy.
The pleural surfaces of the left lung also present a variegated appearance and a few
nodules are felt on passing the hand over them. On section , the tissues present an orange
colour, while on pressure, dark-coloured fluid exudes from the cut ends of the vessels.
The cavity of the pericardium contains nearly ten ounces of a turbid, light-oranoe-
coloured fluid, in which on microscopical examination no hæniafcozoa can be discovered.
Heart—Is somewhat small; weighs 5 lbs. 2 ozs., devoid oF. clots. The base is sur-
rounded by a yellow-coloured exudation, having the consistency of jelly, but both this and
the muscular structure are free from petechiæ. On section, the right side of: the heart is
somewhat dilated, and contains dark-coloured clots bathed in fluid blood but no sub-
endocardial extravasations. The left side is contracted and also contains a small amount of
dark clot, but there are no sub-endocardial extravasations. Valves without alteration
Abdominal Cavity—Contains 6 ozs. of a blood-stained fluid.
Liver— Somewhat small, weighs 9 lbs. 12 ozs., is firm to the touch. Its surface
presents signs of old perihepatitis, the capsule being slightly opalescent:. There are
numerous small calcareous bodies of a yellowish colour, which" show through Glisson's
capsule. On section, the tissues are dark-chocolate in colour, somewhat firm under the
knife. The lobules are large and their colour uniform. Numerous small calcareous bodies
are seen to invade the substance of the organ.
Spleen—Is normal in size and weighs lib. 14 ozs. Externally,yellowish-white
coloured
and dotted over with a few brick-red petechiæ. On section, dark-brown-red ; follicles
normal in size.
Kidneys.—Right
weighs 1 lb. 10 ozs. Left 1 lb. 7 ozs. Both organs present a
healthy appearance.
Stomach.—Small.
On section, it was found to contain a small quantity of semi-
digested food. Cutikular portion healthy. Villous portion also presents a healthy appear-
ance, with the exception of a small 'Spirop)tera' tumor, circular in form, one inch in
diameter, situated at the fundus of the organ one inch from the line of demarcation
Small and Large Intestines — Present a healthy appearance. Two small specimens of
the " Strongylus Armatus" were found in the cæcum.
Bladder.— Contracted. No change in mucous membrane.
Remarks.—This animal, an Australian Gelding, aged 7 years, was purchased by the
Bombay Tramway Company on the 17th April 1S92. Fever developed on the 14th October
1892, after having been in the country exactly six months. A general eruption of Urticaria
appeared on the 24th October, a,nd the hæmatozoon was discovered in the blood on the 30tb
The animal was admitted into the Laboratory Hospital on the 31st October on the 2nd day
of the disease. Treatment was commenced at once, as the animal showed marked loss in
condition, and the disease was progressive. The treatment consisted in the administration
of Iodic Hydrarg (the soluble Double Iodide of Mercury and Potassium) in gradually
increasing doses, commencing with gr. ii up to a maximum of gr. vij and at a later elate
varying the doses according to the condition of the patient. Between the 3rd and 8th of
November the Urticarial eruption appeared every morning but faded by midday on that
date. The hæmatozoon, which disappeared from the blood on the 7th moraine- of the disease
remained absent for a period of ten days, re-appearing on the morning of the 17th day On
the 14th day of the disease and 8th of the intermission three Guinea-pigs were subcuta
neously inoculated with blood (each receiving 0.2c.c., 0.2 c.c. and 0.3c.c. respectively) drawn
from the Jugular Vein of the animal, in order to discover whether any immature form was
present in the circulation during the absence of the hæmatozoon. Hæmatozoa were found
on microscopical examination, in the blood of the two latter Guinea-pigs, after a period of
twelve days, and in that of the former after seventeen days. Continued fever was present
with occasional exacerbations, and well marked but short intermissions occurring at irregular
intervals. As Iodic Hydrarg proved incapable of arresting the development of the hæma-
tozoon, on the 18th day of the disease Quinæ Sulph. was added until the evening of the
22nd. But as the organism re-appeared in the blood on the 24th, Arsenic gr. v bis die was