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CASE No. XLI.—BROWN C. B. MARE, aged, in bad condition and weak.
20th August,
21st
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22nd „
23rd „
24th „
28th „
1891.
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—Temp.
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A.M. 37°C.
„ 36°C.
„ 36.2°C.
„ 35.5°C.
„ 35.8°C.
„ 35.7°C.
P.M. 37.8°C.
„ 36.5°C.
„ 36°C.
„ 36.2°C.
„ 36.3°C.
„ 36.2°C.
Blood
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healthy.
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26th
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12.45 P.M.—Inoculated subcutaneously with 1 c.c. of blood over the
right Scapular region, taken from the heart of Horse No. XL nine and half hours after
death. The injected blood previous to the death of the animal contained very numerous
hæmatozoa. Temp. A.M. 35.8°C., P.M. 36.8°C.
27th.—In the early morning 6 A.M. an Urticarial eruption was noticed on the neck, and
the skin covering the angles of the jaw; the individual patches are smaller than those
noticed previously, but are situated somewhat closely together. There is an oval-shaped
swelling at the seat of inoculation, which measures 5" × 2" × 1"; it is tense and tender to the
touch. Temp. A.M. 36.4°C. No hæmatozoa in the blood. Temp. P.M. 37.2°C.
28th.—The eruption is much more marked than it was yesterday ; the raised patches are
larger and they have extended over the scapular region and ribs on both sides. There are
several petechiæ on the conjunctival membranes, of a dark-red colour. The appetite is good
and the evacuations natural. Temp. A.M. 37.1°C. There are no hæmatozoa in the blood.
Temp. P.M. 37.6°C.
29th.—The eruption has entirely disappeared, but the animal is weaker, and the swelling
at the seat of inoculation has increased in size, and very tender on manipulation. There is
an increase in the number and size of the petechiæ on the conjunctival membranes; the
appetite remains good and the evacuations natural in character. Temp. A.M. 37.5°C. There
are no hæmatozoa in the blood. Temp. P.M. 36.4°C.
30th.—The condition is unchanged. Temp. A.M. 36.3°C. There are no hæmatozoa in the
blood. Temp. P.M. 37.1°C.
31st.—Condition unchanged. Temp. A.M. 37.4°C. There are no hæmatozoa in the blood.
Temp. P.M. 37.8°C.
1st September.—The animal is dull and weaker; there is some swelling and œdema in the
extremities, especially the hind ones. The membranes present a yellowish tinge, and the
petechiæ on the conjunctival membranes are of a deep claret colour. The appetite continues
good and the evacuations normal in character. Temp. A.M. 36.3°C. There are no hæma-
tozoa in the blood. Temp. P.M. 37.8°C.
2nd.—The condition of the animal is more aggravated since yesterday. The œdema of
the limbs has increased, and the appetite is capricious. Temp. A.M. 36.6°C. There is a
decided diminution in the size of the tumor at the seat of inoculation, and the tension
and tenderness of the parts is markedly less. The hæmatozoa are very numerous in the
blood. Temp. P.M. 36.7°C. The animal grew weaker during the evening and, at nine
o'clock, fell; there was no struggling.
3rd.—Death took place at 4 A.M.
AUTOPSY at 10-45 A.M.
Lungs.—There are a few extravasations dotted over the surface of the organs, but
lying under the visceral pleuræ.
Heart.—There are no extravasations on the external surface, but a few .are present under
the endocardium of the left ventricle.
Spleen.—Large, superficial extravasations.
Stomach.—Healthy.
Liver.—Healthy.
Remarks.—This animal was kept under observation from August 20th to the 26th and
appeared to be in good health although in bad condition and weak; she was inoculated on
the 26th with 1 c.c. of blood taken nine and half hours after death from the heart of
Horse No. XL.
A rash appeared similar to that before noticed on the 27th, and on the 28th several
petechiæ were noticed on the conjunctivæ of both eyes. On the 29th there was slight
œdema of the hind legs and these were the only symptoms noted until September 2nd when
numerous Surra hæmatozoa were found in the blood. The temperature continued very
low, never rising above 37.8°C. during the whole time, and the animal fell at 9 P.M. on the
2nd and quietly died at 4 A.M. on the 3rd.
The chief points to notice in this case are :—
(i). The transmissibility of the disease by inoculation of the blood nine and half
hours after death.
(ii). The weakness of the animal, whose temperature had been for some time sub-
normal, accounting for the sudden collapse.
(iii). The presence of an eruption on the skin which appeared the day after inocula-
tion, and five days previous to the detection of the hæmatozoon in the blood.
(iv). The slight pathological lesions found at the Post-mortem.
B 1086—51 ap