cxl v
22nd.— Temp. A.M. 36.3°C. Hæmatozoa very numerous. At 11-45 the animal fell.
Temp. 1-45 P.M. 39.4°C. Death at 1-50 P.M.
AUTOPSY ah 2-30 P.M., 22nd June 1891, forty minutes after death.
The body is somewhat emaciated and there is atrophy of the glutei muscles. There is
no fluid in the pleural cavities and no adhesions of the pleuræ.
Lungs,—Are pale in colour, except where there are irregular shaped dark patches, some
of which are raised above the surface and are hard to the touch. On section these extra-
vasations are found to dip down into and involve the structure of the organ to a depth of
1/8th of an inch. They are most numerous on the inferior surfaces of both organs, but there
are a few scattered on the superior surfaces.
Heart.— The pericardium contains a few ounces of a saffron-coloured fluid. The sub-
stance of the organ is pale, but presents no extravasations on its surface. On section the
right auricle and right ventricle are found to be distended with recent clots and fluid blood.
There are no sub-endocardial ecchymoses in either cavity, with the exception of a small
patch lying between the folds of one of the auriculo-ventricular valves. The left side of
the heart contains recent dark clot with very little free fluid blood; the wall of the ven-
tricle is somewhat hypertrophied.
Liver.—Weighs 11 lbs. 10 ozs. Is large, dark in colour, with some recent perihepatitis
of the left lobe. The organ presents numerous small, round, yellow bodies varying in size
from that of a pin's head to ½" in diameter, all lying under Glissons' capsule and easily
enucleable. On section of the organ these are found deposited in all parts of the organ.
Spleen.—Weighs 2 lbs. 8 ozs. The tissue of the organ is firm and looks healthy on
section. At the pointed extremity of the organ a few ecchymoses are seen lying under the
capsule.
Kidneys.—The organs are pale; the capsules strip off easily; there are no ecchymoses
on the surfaces and on section nothing abnormal is observable.
Stomach.—Is small, contracted ; the walls are thick, the organ weighs 1lb. 13 ozs. Exter-
nally, there is nothing abnormal to be seen. On section the cuticular portion presents a
large collection of " œstridæ " and is somewhat more than usual stained a yellow colour.
The junction between the cuticular and villous portions and for about an inch on to the
former structure, the organ is of a bright orange colour.
The villous portion is considerably thickened, the surface is covered with a glairy
viscid material like white of egg and through this layer the surface of the organ presents
a congested red appearance which when closely examined is found to be made up of small
round isolated petechiæ of a red colour, about half an inch in diameter lying a little distance
apart, the mean distance between them being about 1/5th of an inch. Between these circular
dark red petechias, the mucous membrane of the organ is stained a light reddish hue
due to the dissolved blood pigment.
The intestines are healthy.
The points of interest in this case are :—
(i). That the period of incubation, i.e., from the time of inoculation until the first
appearance of the hæmatozoon in the blood occupied four days.
(ii). The appearance of an ulcer, the size of a two-anna piece, situated on a raised
base, at the entrance to the right nostril on the fourth day after inoculation, and from
which hæmorrhage took place on the fourteenth and sixteenth days of the disease.
(iii). That contrary to the general rule, the swelling at the seat of inoculation be-
came more tender, and did not undergo reduction in size at the time' when the hæma-
tozoon first made its appearance in the blood, but retained the above condition for
several days.
(iv). That no effect was produced on the temperature (41°C) by the exhibition of
large doses of Antipyrin (two drachms).
(v). The appearance of opacity of the cornea of the right eye on the 19th day of
the disease, together with an extensive extravasation of blood into the sclerotic coat
of the same organ.
(vi). The appearance of an eruption of Urticaria over the neck, shoulders and chest,
together with a few patches over the abdomen on the tenth day of the disease.
B 1086—37ap