xlii
drachms of the former and twelve grains of the latter were administered during the
twenty-four hours. From the morning of the 24th October, the hæmatozoon was absent
from the blood, until the 19th November, on which date it reappeared, but one organism
only was discovered in two coverglass specimens of the blood. During this period of
twenty-six days, the temperature gradually fell until it attained a maximum of 37.5°C.
on the morning of the 3rd November and from that date it gradually rose, attaining a
maximum of 40.3°C. on the evening of the 9th November, and again fell to 37°C. on the
14th November and from this date until 20th there were- morning remissions and evening
exacerbations, until on. the latter date 41.5°C. was registered by the thermometer, the
evening previous to death. The medicines were continued in varying doses so as to
accommodate them to the condition presented by the animal until the evening of the
14th November with two exceptions, namely, on the evening of the 12th and morning of the
13th when they were omitted, during which period one hundred and seven drachms of
Cinchona Alkaloids and two hundred and forty-one grains of Arsenic in the form of Liquor
Arsenicalis were administered. At mid-day on the 14th November, serious symptoms were
noticed, the animal appearing almost somnolent, head hanging, eyes dull and heavy, and the
attitude indicative of extreme depression, and œdematous swellings present around the lips
and lower parts of the nose. The surface of the body was cold, especially the extremities,
the internal temperature and the pulse were sub-normal. Stimulants were administered,
chiefly Ammonia, and friction carried out over the body and limbs with a view to exciting
the circulation. This treatment was persevered with until the evening of the 16th, when
owing to fresh crops of petechiæ having made their appearance on the conjunctivæ, it was
deemed advisable to continue with a small dose of Quinine as less irritating than Cinchona
Alkaloids ; this dose was repeated on the following morning, November 17th, but in
consequence of symptoms of gastric irritation having presented themselves Bismuthi and
Opium were given and continued twice daily until the evening of the 19th. On the 20th,
the treatment adopted was Morphia gr.. iss by subcutaneous injection in the morning;
repeated at 6 P.M. Death occurred at 3 A.M. on the 21st.
On the 11th day of the disease a trace of albumen was found in the urine, but nothing
abnormal on microscopical examination of the sediment on standing. On the 20th day the
colour of the secretion changed from an orange to a yellowish-green colour, and a trace of
bile salts and acids was then detected, but no albumen was observed until the follow-
ing day when a trace appeared; then missing a clay it re-appeared, and on the 25th an
appreciable amount, 1/24th was recorded. On this day, for the first time, the microscope
revealed, on examination of the sediment of the urine„ the changes taking place in the
kidneys; red blood corpuscles, epithelial and blood casts were found together with crystals
of Carbonate and Oxalate of Calcium. This condition of things continued until the 31st day
with the exception of the 29th clay, when the albumen was absent. On the former date,
granular took the place of the epithelial casts, and were present until the 35th day after
which no more were observed. The albumen was again, absent from the urine on this date,
but on every subsequent examination until death, with the exception of the 40th, albumen,
was always present—however small in amount—and on the day of death 1/15th was found.
RECORDS OF URINE.
Animal—Bay Australian.
No. LXXII.
Date, October 13th 1892.
Disease—Naturally, acquired Surra.
Date.
1892.
October 13 ...
15 ...
16 ...
17 ...
18 ...
19 ...
20 ...
21 ...
22 ...
23 ...
24 ...
25 ...
26 ..
27 ..
28 ..
29 ..
30 ..
31 ..
Quantity..
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
.....
Colour,
Clear lemon
Do.
Turbid,
viscid,
greenish orange.
Turbid, viscid,
orange.
Turbid, viscid,
lemon.
Do..
do....
Turbid,
viscid,
greenish yellow.
Turbid,
viscid,
yellow.
Turbid, viscid,
orange.
Turbid,
viscid,
creamy yellow.
Turbid,
viscid,
yellow.
Turbid, viscid,
orange.
Turbid,
viscid,
greenish yellow.
Do.
do. ...
Do.
do....
Do.
do....
Turbid,
viscid
yellowish green
Do.
do. ..
Re-action.
Alkaline ...
Do.
Do.
Do.
Do..
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Do.
Specific
Gravity.
1,006
1,008
1,039
1,030
1,010
1,004
1,034
1,028
1,020
1,046
1,026
1,026
1,038
1,034
1,020
1,022
1,020
1,024
Albu-
men..
Nil ...
Nil ...
Nil ...
A trace.
Nil ...
Nil ...
Nil. ...
Nil ...
Nil ...
Nil ...
Nil ...
Nil ...
Nil ...
A trace
Nil ...
A trace
A trace
1/24 th
Phosphates.
Small amount.
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
REMARKS.
Crystals of carbonate and oxalate of
calcium.
„ „
„ „
„ „
„ „
„ „
„ „
„ „
„ „
„ „
„ „
Crystals and Blight trace of bile Ealt
and acids .
II
II
„ „
„ „
„ „
„ „