cxlvi
CASE No. IV—A GREY, COUNTRY-BRED GELDING, aged about 15 years. Is
an old animal and shows evidence of Melanosis, bub is healthy in other respects.
7 th November 1891 —Temp. P.M. 38.4°C.
8th November.— Temp. A.M. 38.1°C., pulse 36. Inoculated at 9 A.M., with xv minims
of blood containing a few hæmatozoa from the Jugular Vein of horse No. III on the left
side of the face.
9th.— Temp. A.M. 38.1o C. No hæmatozoa observed in the blood.
10th. —Temp. A.M. 37.6°C. No hæmatozoa observed in the blood.
llth.—Temp. A.M. 36,8°C. No hæmatozoa observed in the blood.
12th.— Temp. A.M. 37.2°C. No hæmatozoa observed in the blood.
13th.—Temp. A.M. 37.2°C. No hæmatozoa observed in the blood.
14th.— Temp. A.M. 37.2°C, P.M. 38.4°C. No hæimatozoa observed in the blood.
15th.— Temp. A.M. 37.7°C, P.M. 39.8°C. No hæmatozoa observed in the blood.
16th.— Temp. A.M. 39.2°C. Hæinatozoa few in the blood, seven seen in one coverglass
preparation, more or less torpid.
17th.— Temp. A.M. 40°C. The animal appears weak and its gait is unsteady. There
is swelling and oedema of both fore-limbs. The appetite is good. Hæmatozoa numerous
and active in the blood.
18th.— Temp. A.M. 39.1°C. The hind limbs are now becoming swollen and œdematous
and the swelling of the fore-limbs has increased in size. Hæmatozoa very numerous and
active in the blood.
19th.—Temp. A.M. 40.1ºC. Petechiæ present on the conjunctival membranes. The
hæmatozoa very numerous in the blood.
20th.— Temp. A.M. 39.3ºC. The membrana nictitans of the left eye presents a hæmorr-
hagic patch covering nearly the whole of its surface. Temp. A.M. 40.6ºC. Hæmatozoa
very numerous in the blood.
2lst— Temp. A.M. 38,3ºC, P.M. 40.7°C. The œdema of the limbs has increased in
amount. Hæmatozoa very numerous in the blood.
22nd.—Temp. A.M. 38.8°C, P.M. 40.6ºC Hæmatozoa very numerous in the blood.
23rd.—Temp. A.M. 38.4ºC, P.M. 38.3ºC. Hæmatozoa numerous in the blood.
24th.— Temp. A.M. 38°C, P.M. 37.9°C. Hæmatozoa very numerous and active in the
blood.
25th.—Temp. A.M. 38.4°C, P.M. 39.1°C. Hæmatozoa very numerous in the blood.
26th.—Temp, A.M. 38.5°C, P.M. 39.5°C. Hæmatozoa very numerous in the blood.
27th.—Temp, A.M. 38.5°C, P.M. 39.l°C. Hæmatozoa very numerous in the blood.
28th.— Temp.A.M. 39.1°C, P.M. 38.8°C. A hard tumor of the size of a walnut has formed
on the face at the spot from which blood for examination has been repeatedly taken. Hæ-
matozoa numerous in the blood.
29th. — Temp. A.M. 38.4°C, P.M. 38.3ºC. Hæmatozoa numerous in the blood.
30th.—Temp. A.M. 37.7°C, P.M. 37.7ºC. Hæmatozoa numerous in the blood.
1st. December—Temp. A.M. 38.4°C, P.M. 38.9oC. Hæmatozoa numerous in the blood.
2nd.__Temp. A.M. 37.3ºC. A rapid change for the worse has taken place since yester-
day and the horse is in a sinking condition, but he still continues to eat. 2 P.M. fell,
death taking place at 3 P.M.
Remarks.—This was an old horse inoculated for the purpose of keeping up the supply
of the material. He was inoculated on the 8th November and after a period of eight
days the hæmatozoa were found in the blood. On the l6th November they were few in
number, 17th numerous and 18th very numerous, and remained so until the 23rd, when
they became numerous. During this time the temp, oscillated between 38.3ºC and 40.5ºC.
On the 24th the hæmatozoa were again very numerous and remained so until the 28th,
when they again fell to numerous and during these days there had been no corresponding
rise of temperature, the highest point reached being 39.6°C. The hæmatozoa remained
numerous until the 1st December, the temperature, however, falling steadily until the 30th
November on which date there was a slight rise. On the 2nd December the hæmatozoa
were very numerous, but the temperature had fallen to 37.3ºC and death occurred.
The only point of interest beyond the above is that the animal being an old one and
in bad condition the disease was more virulent than usual.