lxxix
tinged a yellow colour, but there were no conjunctival petechias present. The temperature
was 39.2°C. The pulse was hard, frequent 56, and dicrotous, and the respirations were
increased in frequency, 24 per minute. On microscopical examination of the blood, numerous
hæroatozoa were observed. By mid-day the temperature had risen to 40.3°C., but it
had again fallen to 39.1°C. by 5 P.M., and half an hour later an eruption of Urbica,ria was
sparsely scattered over the body, which commenced to fade each evening but re-
appeared each morning until the 3rd December. On the morning of the 30th the tem-
perature had fallen to 38.6°C, P. 52, and the respirations from 28 the previous evening
to 12 per minute, the organisms being very numerous in the blood, the urine however
was not collected. On this day the animal was placed upon an Arsenical treat-
ment consisting of the full physiological dose to begin with, viz., gr. iv bis die. This
was continued for two days, when it was increased to gr. v bis die. On the morning
of the 7th day of the disease a natural intermission took place most probably, for the
hæmatozoon was absent from the blood and remained so until. the 10th day, when a few
were found on microscopical examination. This proved but an abortive attempt on the
part of the hæmatozoon, for on the following day only a few were again observed, and on
the 8th December, the 12th day, none could be seen; thus proving that the Arsenic was
taking effect. From this latter date until the evening of January 1st, 1893, the 36th of the
disease, the temperature never rose above 38.7°C. and for the greater part of the time was
below 38°C. The hæmatozoon had been absent from the general circulation for a period
of twenty-five clays and the animal presented a very satisfactory appearance. Conse-
quently the treatment was discontinued on that evening, and on the morning of the follow-
ing day, but was again exhibited on the evening of the latter day. On the 3rd January,
the 38th day, the organism again made its appearance in the blood. Temp. 37.6°C,
P. 32, R. 12, and although absent on the 39th day, was present in small numbers on the
40th and 41st days, when a well marked crop of Urticaria again appeared, but faded the
same evening. The temperature had by this time risen and registered at mid-day, January
6th, 40'1°C., and for the next fifteen days, 42nd—56th inclusive, during which the hæmato-
zoon was again absent, the temperature oscillated between 40°C. and 37.8°C., the pulse and
respirations remaining within normal limits. At the expiration of this second intermis-
sion, the animal again presented a dull appearance, head hanging, eyes closed, excessive
lachrymation, very little water was taken although the appetite was fairly good, and on the
22nd January, the 57th day of the disease, the organism was again recognized in the
blood, and continued present during the ten days that the animal lived. Numerous and
obscure symptoms presented themselves which were put down to cerebral pressure, as on
several occasions an increased quantity of fluid had been found in the lateral ventricles of
the brain at the Autopsy. This was, however, found not to be the case; the brain presented
a healthy appearance, the chief lesion being found located in the. stomach, which organ
was exceedingly contracted and the mucous membrane of the villous portion deeply in-
jected. During the last week the animal was kept alive upon milk, which it drank readily
for the first few days, but later it had to be administered at stated intervals.
It is a point of clinical interest that during the whole course of this case, which lasted
sixty-six days, albumen was only found in the urine in small quantities, viz., l/40th and
a trace on the 5th and 19th days of the disease respectively. Water, was absolutely
refused on the three days previous to death, and during the same period no urine was
passed. But the secretion removed from the bladder one hour post-mortem was found on
examination to contain a few epithelial and granular casts, a small number of red blood
corpuscles, together with numerous crystals of Uric Acid and Oxalates, and a few Carbonate
of Calcium crystals.
RECORDS OF URINE.
Animal—Bay Australian Gelding, No. LXXV1L
Date, 27th November 1892.
Disease—Naturally contracted Surra.
Date.
1892.
Decr. 1st
„
2nd
„ 3rd
„ 4th
„
5th
„ 6th
„ 7th
„ 8th
„ 9th
„ 10th
„ 11th
Quantity.
...
...
...
...
...
...
...
...
...
...
...
Colour.
Turbid, viscid, orange .
Do.
do.
...
Do.
do.
..
Do.
do,
...
Turbid, viscid, yellow...
Turbid, viscid, orange .
Turbid, viscid, greenish
yellow.
Do.
do.
...
Turbid, viscid, yellow...
Turbid, viscid, greenish
yellow.
Do.
do.
Re- action.
Alkaline ..
Do. ...
Do. ...
Do.
...
Do. ...
Do, ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Sp.
Gravity.
1,030
1,036
1,040
1,038
1,040
1,037
1,040
1,052
1,032
1,038
1,030
Albumen.
l/40th
...
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Phos -
phates.
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
REMARKS.
Carbonates and oxalates of calcium.
„
„
„
„
„ „
„ „
„ „
„ „
„ „
„ „
„ „
Numerous carbonates and oxalate
crystals.