NationalLibraryOfScotland/medical-history-of-british-india huggingface dataset:
IV—continued.
97
f the several cases under investigation.
Small Intestines.
Healthy ...
Do. ...
Few petechiæ dotted
over mucous mombra-
ne. No ulceration.
Healthy
Do.
Do.
Do
Bo
Do
... Mucous membrane-Ec-
chymosed patches dot-
ted. No ulceration.
Healthy
Petechia dotted over
externally.
Healthy
Do. ...
Duodenum, 3 small sub
mucous extravasations
Sm. extravas: invol-
ving 3.5 feet midway
between Pylorus an
I.O.Valve.
Healthy
Do
Do
Do
Do
LARGE
INTESTINES.
Cæcum.
Healthy
Do
Do.
Do.
Do
Do
Do.
...
Do
Do
Do
Do
Do
Do
Do
Several small extra-
vasations. Nuiner-
ous small noma
todes.
Healthy ..
Do
Do
Do
Do
Colon.
Healthy
Do.
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do.
...
..
Do
Do
Do
Do
Do
Do
Rectum,
Healthy
Do.
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
Parasites.
A
A
Sp: Megast... ...
A
A
A
Sp: Megast... ...
A
A
A
A
Ascaris Megalose-
phala.
A
Sp: Megast;
Do.
A
A
A
A
A
Bladder,
Healthy
...
...
Do:
Do,
Do
Do
Do.
Contracted, Gozs,
urine, cluster of
petechiæ at the
base.
Healthy
Do
Do
Do.
...
...
Do
Do
Do
Do
Do
Do
Do
Do
Do
Brain.
Healthy ...
Do.
Do.
Do.
Do.
Do.
Do.
Superficial
veins
congested, convo-
lutions flattened,
Lat: Ven: 3 ozs.
fluid.
Superficial
veins
congested, Lat:
ven: 5 ozs, fluid.
Healthy ...
Do.
Superficial
veins.
Dark. Convolutions
Pale.
increased
fluid in Lat: ven-
tricle.
Healthy.
Do
Do.
Do.
Do.
Do.
Do.
Vessels congested
Convolution. Flat
tencd. Lnt: Yen
Borne fluid.
REMARKS.
A nodule, the size of a wal-
nut was lying free in the
great omentum.
Petechial well marked on the
conjunctival membrane.
Visible mucous membranc
Anæmic.
Mucous membrane covering
the turbinated bones deep-
ly congested. No ulcer-
ation. Yellow exudation in
the subcutaneous tissue of
the abdomen.
98
TABLE
Shewing the Pathological Condition
Number.
Guinea Pig
No. I.
(Sheep).
Goat No. I.
Do. II.
Do. III.
Rabbit No.I.
Do. II.
Guinea Pig
No. 1.
Guinea Pig
No. II.
Guinea Pig
No. III.
Guinea Pig
No. (i).
Guinea Pig
No. (ii).
Rat(M.dec)I.
Do. II.
Do. III.
Rat(N.p.)I.
Do. II
Do. III
Guinea Pig
No. I.
Guinea Pig
No. II.
Guinea Pig.
No.
I.
Tissues.
...
...
...
...
....
...
...
...
...
...
...
...
...
...
...
...
...
...
...
...
Body.
Somewhat
emaciated.
Considerable
emaciation.
Emaciation...
Do.
Poorly nour-
ished.
Emaciation...
Well nourish-
ed.
Emaciation...
Extremely
emaciated.
Slight emacia-
tion.
Emaciation..,
Well nourish-
ed.
Emaciation...
Do.
...
Do.
...
Do. ...
Do. ...
Do.
...
Do. ...
Do. ...
SWELLING
AND
ŒDBMA.
Exter-Scrotum
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
Sheath.
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
Under-
surface
of the
Abdo-
men.
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
Chest.
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
PLEURAL CAVITIES.
Fluid.
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
Adhesions.
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
Trachea.
......
......
......
......
......
......
......
......
......
......
......
......
......
......
......
......
......
......
......
......
LUNGS
Right.
General
Few petechiæ.
Scattered patches of
emphysema. Apex—
Atelectasis. Base-
Tissues deep red
coloured and firm.
Healthy ...
Do. ...
Patches of emphy-
sema.
Emphysema
Circumscribed patches
of emphysema. Ex-
travasations.
Emphysema ...
Apex.—Emphysema.
Middle lobe-Pneum-
onia.
Emphysema ...
Do. ...
Healthy ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Apex—Emphysema..
Do.
Anterior lobe—Pneu
monia.
Left.
emphvsema.
Few petechiæ.
Apex and More
upper } lesses
half. } Lesses of-
Lower half.-
condition of er
sema.
Healthy ...
Do. ...
Patches of em
sema.
Emphysema
Circumscribed pa
of emphysema.
travasatious,
Emphysema
Apex—Emphyse
Emphysema
Do. ...
Healthy ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Apex—Emphys
Do.
Anterior lohe-
monia.
Appendix VII.—continued.
eri cardi al
Fl ui d.
exsess ...
e dr achm.
excess ...
Do.
Do. ...
Do.
Paj achm ...
excess ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
HEART.
Ext ernal l y.
Di st ended wi t h firmclot.
Numer ous ecchymoses
Di st ended
Heal t hy
Do
Di st ended. No
Di st ended, wi t h
Heal t hy
...
Do. ... ... ...
Do. ... ... ...
Di st ended wi t h cl ot s ...
Int ernal l y.
Ri ght .
Few pet echi æ
A.V.} - Bl ood cl ot s
Heal t hy
Do. ...
endocardi al ext ravasa
bl ood cl ot s, no ext ravas
Heal t hy ...
Do- .
t ended wi t h dar k col our
A.
V.} No petechiæ.
Di st ended wi t h dart
cl ot s.
Left .
Few pet echi æ ... ...
A .
V. }- Bl ood clots. . . ...
Heat hy ... ... ...
Do. .... ... ...
t i ons.
at i ons.
Heal t hy ....
Do. ...
ed cl ot s. .
Cont r act ed
A.
V.}-No petechiæ.
Di st ended wi t h cl ot s, no pet echi æ.
Heal t hy ... ... ...
Do. ... ... ...
Do ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Heal t hy. . . . . . . . .
Do. ... .... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Heal t hy ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do.
Do.
Do. ...
Do. ...
Fl ui d i n
Peri t oneal
Cavi t y.
A
10 ozs..
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
LI VER.
Perihepati-
tis.
A
Convex A l ayer
A
P
A
A
Large. Gal l -
di st ended
A
A
lar
Large. Gal l -
of cl ear
A
lar
A
A
A
A
A
A
A
Enl A
Enl A
Concr et i ons.
A
s ur f ace—
of l ymph.
A
A
A
A
bl adder
wi t h cl ear
fluid..
A
A
ge. bl adder f ul l
fluid.
A
ge. A
A
A
A
A
A
A
arged. A
arged. A
Spleen.
Much enlarged, 10 times
normal size.
Somewhat enlarged, con-
vex surface. A layer of
lymph.
Healthy
Attached to the stomach
by firm bands of lymph.
Small...
Healthy
Considerably e n la r g e d.
On section.—The tissues
firm and full of blood
containing numerous
homatozoa.
Very small ...
...
...
Enlarged to 3 times nor-
mal size.
Large. Ho petechias
Do. ...
Much enlarged. Patches of
extravasations.
Much enlarged. Patches of
extravasations,
Much enlarged. Patches of
extravasations.
Considerably enlarged ...
Do. ...
Do. ...
Enlarged enormously ...
Enlarged
...
...
...
Enormously enlarged ...
KIDNEYS.
Eight.
Smal
dot.
Left.
l petechiæ.
ted
Cortical portion—Mumerous yellow coloured Sphe-
rical concrctions.
Healthy
Do. ... ... ...
Do.
...
...
...
Do. ... ... ...
Do. ... ... ...
Do. ... .... ...
Few pe
Healthy
Large
...
Healthy
....
Do. ...
Do.
Do.
...
...
...
Do.
Do.
Do.
Do.
...
Do.
...
Healthy
...
Do.
...
...
...
Do.
...
...
...
Do.
...
...
...
Do.
...
...
...
Do
...
techiæ.
Healthy
Large
...
Healthy
Do.
Do.
Do.
...
...
Do.
...
...
...
Do. ... ... ...
Do.
Do.
Do.
...
...
Do
STOMACH.
Cuticular portion.
Healthy ... ...
Do.
...
...
Do
Do.
...
...
Pyloric mucous mem
thick
Healthy
V. Shaped clot near
ulcera
Healthy
Pyloric extremity con
Healthy
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
On section—Dark red
mucous membranes.
spots found in
Healthy
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Villous portion
Healthy ...
Do. ...
Do. ...
Do. ...
brane considerably
ened.
Healthy ...
pylorus. Mucous id
ted.
Healthy ...
gested. No ulcerat
Healthy ...
Do. ...
Do. ...
Do. ...
Do. ...
clot involves 1/6 th su
On removal petechi
the rugæ.
Healthy
...
Do. ...
Do. ...
Do. ...
Do. ...
XV—continued.
101
of the several cases under investigation,
Small Intestines.
Healthy
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Duodenum
distended
with gas.
Healthy ...
...
...
Do. ... ... ...
Do. ...
...
...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
LARGE INTESTINES.
Cæcum.
Healthy
...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Do. ... ... ...
Colon.
Healthy
...
Do. ... ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Rectum.
Healthy ... ...
Do.
...
...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do.
...
...
Do. ... ...
Parasites.
A
A
Cænurus cerebra-
lis.
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
A
Bladder.
Healthy
...
...
Do.
... ...
Do.
...
..
Do.
...
...
Greatly distended
with urine.
Healthy
...
...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Brain.
Healthy ... ...
Lat: Ven: consider
able quantity of
milky fluid. Atro-
phy cerebral cortex
from presure.
Cystic tumour
Convolutions —Flat-
tened Lat: Ven:
dilated with col-
ourless fluid.
Healthy
...
...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
Do. ... ...
REMARKS.
Omentum dottad over with
petechiæ Hydatid cyst,
size of walnut attached to
omentum in L. lumbar
region.
Testicles—T. V. wall adhe-
rent L. T. on section seat
of inflamatory change.
Testicles-Hard, Cord thich-
ened.
Swelling of integument
nose, mouth and eyes.
B1086—26
102
TABLE XVI.
Showing the number of cases in which the various Pathological conditions were present or absent, and the different organs healthy or unhealthy.
Appendix
I ... ...
Do.
...
...
Do.
III ... ...
Do.
IV ... ...
Do.
V ... ...
Do.
VI ... ...
Do. VII ...
...
BODY.
Emaciation.
8
1
...
5
1
2
17
Slight Emaciation.
9
1
1
3
3
3
4
Extreme Emaciation,
1
...
...
...
...
1
Well nourished.
1
...
1
1
1
2
3
Comciderable emacia-
tion
...
...
...
2
3
...
1
SWELLING AND ŒDEMA.
Extremities.
P.
5
1
1
6
1
3
...
A.
14
1
1
5
6
4
26
Scrotum.
P.
...
...
1
8
3
1
...
A.
19
2
1
8
4
6
20
Sheath.
P.
1
...
2
2
3
1
...
A.
13
2
...
9
4
6
26
Under-sur-
face of
Abdomen.
P.
2
...
2
5
4
3
...
A.
17
2
...
6
3
4
26
Cheat.
P.
6
...
...
1
8
...
...
A.
13
2
2
10
4
7
26
PLEURAL CAVITIES.
Fluid.
P.
7
...
...
3
1
...
1
A.
12
2
2
8
6
7
25
Adhesion.
P.
2
...
...
1
...
...
...
A.
17
2
2
10
7
7
26
Trachea.
P.
2
...
1
1
...
...
1
A.
17
2
1
10
7
7
25
LUNGS.
Emphysema.
Right.
P.
16
2
2
5
3
4
15
A.
3
...
...
6
4
8
11
Left.
P.
15
2
2
5
4
4
16
A.
4
...
...
6
3
3
11
Pneumonia.
Bight,
P.
4
1
...
1
...
...
4
A.
15
1
2
10
7
7
22
Left.
P.
7
...
...
...
1
2
2
A.
12
2
...
...
6
5
24
Concretions.
Bight.
P.
2
1
...
...
1
3
...
A.
17
1
...
9
6
4
26
Left.
P. A.
2
1
...
3
1
4
...
17
1
...
8
6
3
26
Pericardial
fluid.
P.
15
1
1
8
3
4
2
A.
4
1
1
3
4
3
24
P = Present.
A =
Absent.
* Out of the 13 cases of Appendix IV two of the animals had undergone decomposition.
103
TABLE XVI—continued.
Showing the number of cases in which the various Pathological conditions were present or absent, and the different organs healthy or unhealthy.
Appendix
Do.
Do.
Do.
Dp.
Do.
Do.
I ...
II ...
III ...
IV ...
V ...
VI ...
VII ...
HEART.
Externally.
H.
4
1
...
1
2
1
19
N.H.
15
1
2
10
5
6
7
Internally.
Right.
H.
3
...
...
2
...
1
18
N. H.
16
2
2
9
7
6
8
Left.
H.
3
..
...
..
...
...
10
N. H.
16
2
2
11
7
7
7
Fluid in
peritoneal
Cavity.
P.
4
...
1
1
...
1
1
A.
15
2
1
10
7
6
25
LIVER.
Perihepatitis
P.
17
2
2
8
7
6
3
A.
2
...
...
3
...
1
23
Concretions.
P.
7
1
2
7
5
5
...
A.
12
1
...
4
2
2
26
Spleen.
H.
1
...
...
1
1
...
2
N.H.
18
2
2
10
8
7
24
KIDNEYS.
Bight.
H
7
1
...
4
2
1
22
N.H.
12
1
2
7
5
6
4
Left.
H.
9
1
4
2
1
22
N.H.
10
1
2
7
5
6
4
STOMACH.
Cuticular
portion.
H.
15
1
1
8
5
5
22
N.H.
4
1
1
3
2
2
4
Villous
portion.
H.
1
1
1
3
2
2
21
N.H.
18
1
1
8
6
5
5
Small
Intestines.
H.
9
1
8
6
5
24
N.H.
10
1
2
3
1
2
2
LARGE INTESTINES.
Cœcum.
H.
13
2
2
11
7
7
25
N. H
6
...
...
...
...
...
1
Colon.
H.
15
2
2
11
7
7
26
N.H.
4
...
...
...
...
...
...
Rectum.
H.
15
2
2
11
7
7
26
N. H.
4
...
...
...
...
...
...
Parasites.
P.
13
...
1
2
2
3
2
A.
6
2
1
9
5
5
24
Bladder.
H.
12
2
2
10
6
7
25
N.H.
7
...
...
1
1
...
1
Brain.
H.
15
2
2
10
7
4
22
N.H.
4
....
...
1
...
3
4
H = Healthy.
N H = Not healthy.
104
SECTION XIII.
EXPERIMENTAL ENQUIRY INTO THE TREATMENT OF SURRA.
Few observers have tried any systematic treatment with regard to ' Surra'
cases, and those few who have, unfortunately have only had negative results
to record.
Evans tried Carbolic Acid in Glycerine (1 in 4) in large doses in four cases,
but all succumbed. The late Veterinary Surgeon Steele informed me, that he had
made a series of experiments with different drugs, especially mentioning Mer-
curic perchloride, but that all his cases in like manner proved fatal.
Pottinger experimented with large doses of Sodii. Hyposulphis. and Potass.
Nitras. given in drinking water. He also tried Arsenic, Aconite, and Quininœ
Sulphas, but was unable to find that any of these drugs exercised any control
over the disease. Frost tried Sodii Hyposulphis, Salycilic and Carbolic Acids,
but these were in all cases ineffectual.
In my own experiments, horses submitted to experimental treatment com-
prised—
(i) The subjects of naturally contracted Surra,
(ii) The subjects of experimental inoculation.
The methods of treatment made use of include—
(A) Rational therapeutic remedies.
(B) The subcutaneous inoculation of blood and its derivatives in its dif-
ferent forms, obtained from animals suffering from, or which had lately
succumbed to, Surra.
(a) Serum from blood (the latter containing swarms of the Surra hæma-
tozoa), after being passed through a porcelain filter.
(6) The injection of proteids dissolved in Glycerine and water, after
precipitation from live Surra blood.
(c) Subcutaneous injection of blood obtained from an animal of the
bovine species, recently the subject of Surra, but which after a
second inoculation of virulent material was proved protected
against the disease.
The plan which has been adopted in the following pages is first to describe
the various chemicals with regard to their respective bacteriocidal and antiseptic
properties, and then to give a short resumé of the several cases in which they
have been employed, together with the results.
A.—RATIONAL THERAPEUTIC REMEDIES.
The following chemicals were selected as being those most likely to effect
a destructive action on the hématozoon:—
Mercuric Perchloride
...
...
HgCl 2
Iodine and Potassium Iodide ...
I; KI
Potassium Bichromate
...
K 2 Cr 2 O 7
Iodoform
...
...
CHI 3
Oleum Terebinthinse
Carbolic Acid and Iodine
...
C 6 H 6 O
Cinchona Alkaloids and Arsenic in combination.
Double Iodide of Potassium and Mercury.
Quinine Sulphate.
Liq. Potassse
...
...
KHO
Arsenic ...
...
...
AS.
Mercuric Perchloride is one, if not the most powerful, antiseptic known,
It has the power of combining with albumen, forming albuminates, and accord-'
ing to M. de la Croix,* confirmed by Koch, 1:6500 of water sufficed to prevent
* Lauder Brunton Pharmacology and Therapeutics, page 90,
120
42nd day. Notwithstanding that the animal's appetite continued to be very good, and that
the condition was fairly maintained, it was decided to abandon the. treatment for the fol-
lowing reasons:—
(i) Because 525 grains of Arsenic had already been taken by the animal.
(ii) In order to test the efficacy of the treatment, and so encourage the return of the
Surra hæmatozoon in the blood, if still present in the body tissues, two Guinea-
pigs were inoculated with .0.5 c. C. of blood taken from the Jugular Vein on the
17th February 1893, just after the last dose of Arsenic was taken by the animal.
(iii) In some cases the abrupt discontinuation of Arsenic appeared to be followed in the
animal by a rapid waste of tissue, and this was deemed a good opportunity for
making an observation. On the morning of the 20th February, the third day after
discontinuing the Arsenical treatment, the animal presented a dull appearance, the
abdomen was tucked up, and the appetite had somewhat fallen off. The swelling
and œdema of the extremities, which had completely disappeared, now returned in
the fetlocks.
Arsenic.
Case No. LXXXIV.—This animal was placed upon a treatment of Arsenic, the dose
consisting of gr. iv. bis die. in the form of Liq : Arsenicalis,
which was gradually increased until it reached gr. v. The
hæmatozoon which was absent from the blood on the morning of the first exhibition of the
metal, continued so for a period of eleven days, including the six during which fifty-five
grains of Arsenic were administered, and the five following days. The organism re-appeared
in the blood on the 12th day, and death occurred two days later. From first to last the
course of the disease occupied 18 days.
122
TABLE XVII-continued.
Horse
Number.
LXXIV
LXXVI
LXXVII
XXXVIII
LXXIX
LXXX
LXXXI
LXXXII
LXXXIV
Treatment.
Santonin ... ... ... ... ...
Iodic Hydrarg
...
...
...
...
Quinine ... ... ... ... ...
Arsenic ... ... ... ... ...
Potassæ Hydrate ... ... ... ... ...
Arsenic ... ... ... ... ...
Arsenic ... ... ... ... ...
Arsenic ... ... ... ... ...
Arsenic ... ... ... ... ...
Arsenic ... ... ... ... ...
Arsenic ... ... ... ... ...
(i) ...
(ii) ...
(iii) ....
Arsenic ... ... ... ... ...
Arsenic ... ... ... ... ...
How administered.
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Minimum dose.
30 grains, 1.94 grammes ...
4 grains, 0.25 grammes ...
180 grains, 11.65 grammes...
6 grains, 0.32 grammes ...
14 grains, 0.907 grammes ...
3 grains, 0.19 grammes ...
4 grains, 0.25 grammes ...
4 grains, 0.25 grammes ...
4 grains, 0.25 grammes ...
3 grains, 0.19 grammes ...
3 grains, 0.19 grammes ..
5 grains, 0.32 grammes ...
5 grains, 0.32 grammes ...
3 grains, 0.19 grammes ...
4 grains, 0.25 grammes ...
Maximum dose.
30 grains, 1.94 grammes ...
6 grains, 0.33 grammes ...
180 grains, 11.65 grammes...
6 grains, 0.38 grammes ...
175 grains, 1.133 grammes..
7 grains, 0.45 grammes ...
6-5 grains, 0.42 grammes..
6 grains, 0.38 grammes ...
6 grains, 0.38 grammes ...
6 grains, 0.38 grammes ...
7.5 grains, 0.48 grammes..
7.5 grains, 0.48 grammes...
5 grains, 0.82 grammes ...
6.5 grains, 0.42 grammes...
4.5 grains, 0.29 grammes ...
TOTAL QUANTITY OF
BACH DRUG
ADMINISTERED IN
Grains.
60
[56
540
274
220.75
813
560
116
177
427
274
525
65
Grammes.
3.88
3 62
34.95
17.75
14.304
20.28
36.28
7.51
11.46
27.66
17.75
34 02
3.56
Date From—
To under each
form of
Treatment.
10 11 92
11 11 92
16 11 92
21 11 92
15
20 } 11 92
2l 22 11 92
14 12 92
26 11 92
1 12 92
3 12 92
3 1 93
30 11 92
26 1 93
7 12 92
17 12 92
7 12 92
22 12 92
11 12 92
24 1 93
23 12 92
8 1 93
11 1 93
20 1 93
24 1 93
26 1 93
23 12 92
17 2 93
28 1 93
2 2 93
Number
of days
under
form of
Treat-
ment.
2
6
...
23
6
32
57
11
16
45
17
10
3
57
6
Date of dis-
appearance
of hœmatozoa
from the
blood.
16 11 92
23 11 92
28 11 92
27 11 92
9 11 92
3 12 92
8 12 92
4 1 93
7 1 93
11 11 92
10 12 92
13 12 92
25 12 92
29 12 92
14 1 93
24 1 93
25 12 92
28 1 93
Date of re-
appearance of
hæmatozoa in
the blood.
19 11 92
19 11 92
27 11 92
15 12 92
28 11 92
6 12 92
3 1 93
5 1 93
22 1 93
......
......
......
26 12 92
2 1 93
19 1 93
25 1 93
........
8 2 93
Number
of days
hæma-
tozoa
absent.
...
3
3
4
18
1
27
3
26
1
15
7
13
44
1
4
5
1
64
11
Result of
Treat.
ment.
Nil
...
Nil
...
Nil
}Death...
Nil
...
Death ...
Death ...
Death ...
Death ...
Death ...
Nil ...
Nil ...
Death ...
Death ...
Death ...
Number
of days
which
elapsed
between
the first
appear-
ance of
disease
and
death.
38
40
65
12
16
46
41
70
17
Number
of days
under
Treat-
ment for
Surrs.
31
38
57
11
16
45
30
57
6
HORSE SURRA
LIST OF APPENDICES TO THE REPORT.
APPENDIX I.—Naturally-contracted Surra Cases :—
Horses I, II, III, X, LVI, LXV, LXX, LXXI, LXXII, LXXIII
LXXIV, LXXVI, LXXVII, LXXVIII, LXXIX, LXXX,
LXXXI, LXXXII, LXXXIV
„
II,—Experimental cases by Gastric Ingestion of blood :—
Horses XX, XXVI.
„ III.—Experimental cases—Direct Injection of blood into the Jugular Vein :—
Horses XIV, XV.
„
IV.—Experimental cases—Subcutaneous Inoculation with Ante-mortem
blood:—
Horses V, VIII, VI, XXII, IV, XXX, XXI, XXIX, LXIV, LIX,
LIV, LV, XXIV.
„
V.—Experimental cases—Subcutaneous Inoculation with Post-mortem
blood:—
Horses XVIII, XIX, XXVII, XXIII, XI, XXXII, VII.
„
VI.—Experimental cases—Subcutaneous Inoculation of blood previously
passed through the Goat ;—
Horses XXXIII, XXXIV, inoculated with Ante-mortem fluids.
Horses XXXVIII, XLI, XL, XXXI, L, inoculated with blood obtained
Post-mortem.
„ VII.—Experimental cases—Various animals inoculated with Surra Horse
blood and other fluids :—
Bull—Guinea-pigs inoculated from.
Sheep—Guinea-pigs inoculated from.
Goats Nos. I, II, III.
Rabbits.
Guinea-pigs.
Eats (Mus decumanus).
Rats (Nesokia providens).
Fowls.
Pigeons.
„ VIII.—Inoculation of—
Small animals with urine of horses.
Guinea-pigs with pericardial fluid.
Guinea-pigs with cerebro-spinal fluid.
„ IX.—Experimental Treatment.
B 1086—1 ap
APPENDIX I.
NATURALLY-CONTRACTED SURRA CASES.
HORSES I, II, III, X, LVI, LXV, LXX, LXXI, LXXII, LXXIII, LXXIY,
LXXVI, LXXVII, LXXVIII, LXXIX, LXXX, LXXXI, LXXXII,
LXXXIV.
RECORDS OF TEMPERATURE, PULSE AND RESPIRATION.
xliii
Date.
1882.
November 1 ...
2 ...
3 ...
4 ...
5 .
6 ...
7 ...
8 ...
9 ...
10 ...
11 ...
13 ...
14 ...
15 ...
16 ...
21 ...
Quantity.
......
Colour.
Turbid,
viscid,
yellowish green.
Do.
do....
Do.
do....
Tuvbid,
viscid,
orange yellow.
Turbid, viscid ...
Do.
Turbid,
viscid,
yellow.
Turbid,
viscid,
yellow brown.
Turbid,
viscid,
yellowish green.
Turbid,
viscid,
bright yellow.
Do.
do. ...
Turbid,
viscid,
orange.
Clear lemon
Turbid, pale yel-
low.
Turbid, viscid,
orange.
Turbid,
viscid,
white of egg.
Re-action.
Alkaline ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Do. ...
Specific
Gravity.
1,024
1,032
1,038
1,041
1,028
1,030
1,026
1,042
1,046
1,040
1,035
1,028
1,010
1,014
1,020
1,030
Albu¬
men.
l/30th.
A trace.
A trace.
Nil ...
Slight
trace.
Nil ...
A trace.
l/22nd.
A trace.
l/45th.
A faint
trace.
A slight
tracd
A slight
trace.
A faint
trace.
Nil ...
l/15th.
Phosphates.
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Nil
Trace
REMARKS.
Epithelial and blood casts, red blood
corpuscles and crystals slight trace of
bile salts and bile acids.
Blood casts, trace of bile salts and bile
acids, crystals of carbonate but no
oxalate.
Epithelial and blood casts, carbonate and
oxalate crystals.
Epithelial casts, red-corpuscles, carbo-
nates and a few oxalates.
A few small epithelial casts, no blood
crystals.
Granular casts.
Granular casts,
Granular casts oxalates but no carbo-
nates.
Granular casts, oxalates and few carbo-
nates and crystals of nitrate
Few granular casts, large numbers of
carbonate but no oxalates.
Granular casts, red blood corpuscles,
casts and oxalates.
No casts, crystals of carbonate and
oxalate of calcium.
No casts
„
„
No casts
„
„
No casts
„
„
No casts
.,
„
HORSE
NO. LXXIV.
PHOTOGRAPHED ON NOVEMBER 23RD 1892. THE 17TH DAY OF THE DISEASE.
HORSE
NO.
LXXIV.
PHOTOGRAPHED ON THE 9TH DECEMBER 1892 TO SHEW THE CONDITION OF THE ANIMAL ON THE 33RD DAY OF THE DISEASE.
HORSE NO. LXXIV.
INTERNAL
SURFACE
OF
THE
LEFT
VENTRICLE
OF
THE
HEART.
SHEWING
EXTENSIVE
SUB-ENDOCARDIAL
EXTRAVASATIONS
OF
BLOOD.
HORSE
NO.
LXXIV.
INTERNAL
SURFACE
OF
THE
LEFT
VENTRICLE
OF
THE
HEART.
SHEWING
EXTENSIVE
SUB-ENDOCARDIAL
EXTRAVASATIONS
OF
BLOOD.
HORSE
NO.
LXXIV.
INNER SURFACE OF STOMACH, SHEWING TWO SPIROPTERA TUMOURS INVADING THE VILLOUS PORTION OF THE ORGAN.