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CASE No. L.—BROWN AUSTRALIAN MARE, aged, 16 hands.
15th October, 1891.—Inoculated subcutaneously over the left Scapular Region with 2 c. c.
of blood serum, drawn from the Jugular Vein of Horse No. XXXVIII after clotting had
taken place, forty-five minutes post-mortem. Temp. P.M. 37.2°C.
16th.—Temp. A.M. 37.2°C., P.M. 37.4°C. Blood healthy. There are no conjunctival
ecchymoses and no sign of swelling at the seat of inoculation.
17th.—Temp. A.M. 37.2°C., P.M. 37.7°C. Blood healthy.
18th.—There is one ecchymosis on the right membrana nictitans, but no swelling or
œdema at the seat of inoculation, although there is some swelling of the left mammary
gland. Temp. A.M. 37.3°C. No hæmatozoa in the blood. Temp. P.M. 37.6°C.
19th.—There is some slight swelling at the seat of inoculation, and the left mammary
gland is increased in size; there is tenderness on manipulation in both situations. Temp.
A.M. 37.6°C. No hæmatozoa in the blood. Temp. P.M. 38°C.
20th.—The swelling and œdema at the seat of inoculation has extended since yesterday,
and the condition of the mammary gland remains unchanged. Temp. A.M. 38.3°C. P. 60.
R. 15. There are no hæmatozoa in the blood. Temp. P.M. 38.4°C.
21st—The condition of the swelling at the seat of inoculation and that of the mam-
mary gland remain unchanged. Temp. A.M. 39.4°C. Hæmatozoa absent from the blood.
Temp. P.M. 40.9°C.
22nd.—There is considerable swelling and œdema of the off hind limb from the
coronet up to the knee, but it is not painful on manipulation. There are several petechiæ
on the right membrana nictitans. Temp. A.M. 39.5°C. No hæmatozoa in the blood.
Temp. P.M. 39.3°C.
23rd.—The condition of the animal is unchanged. Temp. A.M. 38.3°C. No hæmatozoa
in the blood. Urine, turbid, viscid, orange in colour. Sp. Gr. 1,032, alkaline. Temp. P.M.
38.5°C.
24th.—The animal is dull and the head hangs down ; the petechiæ have increased in
number on the conjunctival membranes. The appetite is not so good as it has been
since the date of inoculation. The swelling at the seat of inoculation is soft and some of
the tension and tenderness of the parts has disappeared. Temp. A.M. 37.8°C. The hæmato-
zoa are very numerous in the blood. Urine, turbid, viscid, reddish-yellow in colour. Sp. Gr.
1,034, alkaline. Temp. P.M. 40.6°C.
25th.—The animal still continues dull, the skin is hot, and the visible mucous mem-
branes present a dusky pallor. Temp. A.M. 41°C. Hæmatozoa are numerous in the blood.
Urine, turbid, reddish in colour. Sp. Gr. 1,016., neutral. Temp. 1 P.M. 40.8°C., 5 P.M.
39.6°C.
26th.—There is an Urticarial eruption on both sides of the neck; the individual patches
are oval in form, and raised above the surrounding skin. On manipulation these small
tumors appear to be distended with jelly-like material. Temp. A.M. 37.8°C. Hæmatozoa
are absent from the blood. Urine, turbid, viscid, orange in colour. Sp. Gr. 1,026, alkaline.
Temp. P.M. 38.5°C.
27th.—The eruption has all disappeared this morning and the animal is much
brighter ; the appetite is good and the evacuations normal. Temp. A.M. 39°C. P. 64. R. 30.
Hæmatozoa few in the blood. Urine, turbid, viscid, greenish-brown in colour Sp. Gr. 1,028,
alkaline, a trace of albumen, Carbonates, no phosphates. Temp. P.M. 39°C.
28th.—The condition is unchanged, except that there are extensive ecchymoses on both
conjunctival membranes. Appetite good. Temp. A.M.38.4°C. Hæmatozoa absent from
the blood. Urine, turbid, viscid, greenish-brown in colour. Sp. Gr. 1,024, alkaline, a
trace of albumen, Carbonates, Oxalates, no phosphates. Temp. P.M. 38.4°C.
29th.— The animal continues to be brighter, and feeds well. Temp. A.M. 37.4°C.
Hæmatozoa absent from the blood. Urine, turbid, viscid, orange in colour. Sp. Gr. 1,036,
alkaline, a trace of albumen, Carbonates, no phosphates. Temp. P.M. 37.6°C.
30th.—The condition of the animal is unchanged. Temp. A.M. 40°C. Hærnatozoa
numerous in the blood. Urine, turbid, viscid, dirty orange. Sp. Gr. 1,032, alkaline, a trace
of albumen, no phosphates, Carbonates. Temp. 1 P.M. 41.3°C., 5 P.M. 40.4°C.
31st. — The visible mucous membranes are pale; the conjunctival membranes are dotted
over with ecchymoses especially the membrana nictitans of both eyes. There is some swelling
of the extremities, especially the off hind limb which has continued large since the 22nd
instant. The appetite is very good and the evacuations are normal. Temp. A.M. 39.7°C.
Hæmatozoa are very numerous in the blood. Urine, turbid, viscid, dirty orange in colour.
Sp. Gr. 1,036, alkaline, a trace of albumen, and Carbonates, no phosphates. Temp. 5 P.M.
38.3°C.