xcix
frequent, small and thready pulse, and on microscopical examination, the hæmatozoon was
found in small numbers in the blood. After keeping the animal under observation for two
days, the temperature in the meantime falling from 39°C. to 37.6°C, it was subjected to a
treatment consisting of two doses of Arsenic daily in increasing doses in the form of Liq.
Arsenicalis, P.B., the first dose having been given on the morning of the 23rd December.
(Arsenic grs. iv). Temp. 40.1°C. The hæmatozoa were numerous in the blood. On the
morning of the 24th, the temperature fell to 37.7°C. and the hæmatozoa were few, and by the
following day the former registered 37.5°C. and the latter was absent from the blood. From
this date until the evening of the 28th,- the temperature steadily rose until it attained a
maximum of 40.4°C. at 5 P.M., the organisms being present in small numbers in the blood.
One hour later the animal suddenly passed some ten ounces of urine, of a dark-red colour,
which on microscopical examination was found to contain a few red corpuscles and blood casts.
By the morning of the 29th, the temperature had fallen 1.4°C. and continued to do so until
8 A.M. on January 1st, 1893, when it registered 36.8°C. During this period the hæmatozoon
was absent from the blood. On the evening of the same day the temperature again
rose to 39.4°C. but again fell two degrees by the morning of the 2nd at which time the
organism had again appeared in the circulation, and continued present until the 7th. By the
evening of the 3rd the temperature had attained a maximum of 40.7°C, P. 72, R. 20, but
during the night a sudden fall took place of 3.3°C. (5.9°F.) P. 60, R. 16, but no alteration
was observed in the number of hæmatozoa present in the blood.
From the 4th until the morning of the 16th, three exacerbations followed by recrudes
cences in temperature took place, eacli period lasting several days, the maxima occurring on the
5th, 9th, and 14th, when the following thermometric observations—39.7°C, 40.3°C and 40.8°C.—
were respectively registered; the lowest minimum, temperature, 37.6°C, being recorded on
the morning of the 11th.
The Arsenical treatment was omitted from the evening of the 8th January to that of the
11th in consequence of the animal taking little or no water to drink, but from the 21st to the
23rd of January the animal absolutely refused water.
On the morning of the 10th, the temperature was 38.1°C. and the hæmatozoon absent
from the blood, but from this date until the evening of the 23rd the former gradually became
elevated until it registered 40.4°C, the organisms varying during this period between absent;
and very numerous. Again a recrudescence in the temperature 3'6°C. (6.5°F.) occurred, but
this time the fail was gradual and occupied a period of thirty-six hours. An abrupt fall,
however, occurred in the number of hæmatozoa, for in a single night—the 23rd, when very
numerous, they were found to be absent on the morning of the 24th. The last paroxysm
occupied 72 hours and terminated in death. The temperature, which registered on the
morning of. the 25th, 36.8 o C., rose to 38.5°C. at noon, but fell to 37.l°C. at 5 P.M. On the
following evening, after rising gradually all day, it was 39.3°C. and by mid-day on the 27th it
attained its maximum height 39'6°C. and finally registered 36.8°C. at death on the 28th at
9'30 A.M. The animal lived 42 days from the discovery of the organism in the blood. Six
paroxysms occurred lasting in all 29 days, during which the hærnatozoon was present, and
five intermissions occupying 13 days—-the animal dying at the commencement of the sixth
intermission during which the organism was absent from the blood.
RECORD OF URINE.
Animal, Grey Herati Mare, No. LXXXI.
Date 18th December 1892. Disease " Surra ",
naturally contracted.
Date.
Quantity.
1892.
December 24 ...
„ 25 ...
„ 26 ...
„ 27 ...
„
28 ...
„
29 ...
„ 30 ...
„ 31 ...
1893.
January,
1
„ 2
„
3 ...
„
4 ...
...
...
...
...
...
...
...
...
...
...
...
...
...
Colour.
Turbid, viscid, yellow...
Turbid, viscid, orange
yellow.
Turbid, viscid, yellow...
Turbid, viscid, yellow...
Turbid, viscid, yellow...
Turbid, viscid, smoky-
red.
Turbid, viscid, porter...
Turbid, viscid, porter...
Turbid, viscid, like por
ter.
Turbid, viscid, orange...
Turbid, viscid, brown...
Turbid, viscid, dark ...
Re-action.
Alkaline
Alkaline
Alkaline
Alkaline
Alkaline
Alkaline
Alkaline
Alkaline
Alkaline
Alkaline
Alkaline
Alkaline
Gravity.
1,034
1,034
1,026
1,026
1,025
1,028
1,036
1,040
1,046
1,044
1,030
1,030
Albu
men .
Nil ...
Nil ..
Nil ...
Nil ...
A trace
⅛th ...
⅛th ...
1/7th ...
1/6th ...
1/5th ...
Nil ...
Nil ...
Phos
phates.
...
...
...
...
...
...
...
...
...
...
...
...
...
REMARKS.
Calcium carbonate ; no oxalates.
Calcium carbonate crystals ; no oxalates ;
no casts.
Do.
do.
Do.
do.
A few blood casts ; carbonate crystals.
Do.
do.
Enormous numbers of granular casts; also
a few blood casts from narrow, Medium
and broad tubes; a few large oxalate,
but no carbonate crystals.
Do.
do.
Do.
do.
Few
do.
do. + CaCo3
Few
do.
do.
do.
Few
do.
do.
do.