xxix
No hæmatozoa were discovered in the blood on microscopical examination, but we were
unable to decide whether this absence was the result of the treatment, or whether it was
one of the natural phases of the disease. It was, therefore, resolved to continue the medi-
cine, and the horse received, during the day, Carbolic Acid 3vi and Iodine 3iii.
On the morning of the 28th, the animal looked bright and well, the number of respira-
tions had decreased considerably, but a microscopical examination of the blood revealed the
presence of a few hæmatozoa. The amount of Carbolic Acid and Iodine was, therefore,
increased, twelve of the former and sis and a half drachms of the latter were administered
during the day. From the 29th, the general condition of the animal was unchanged and
there were few and active hæmatozoa in the blood. The amount of the medicine was,
therefore, again increased, the animal receiving Carbolic Acid 3xxiv and Iodine 3viii. On
the 30th, no effect appeared to have been produced on the health of the animal by the drug,
the appetite and general appearance being as before. The only effect noticed being in
connection with the urine, which assumed a brownish-black colour, and exhibited an inky
line on the addition of a small quantity of Nitric Acid to it. On microscopical examination
of the blood, the organisms were found to be numerous. The animal received, during this
day, Carbolic Acid 3xv and Iodine 3viiss. On October 1st, the animal showed the first
symptoms which might be referred to the action of the drugs, appearing slightly uneasy
after taking food. On microscopical examination of the blood, no hæmatozoa were detected.
Taking into consideration the symptoms evinced by the animal, it was decided to discontinue
the administration of the medicine, as it was deemed to have had a fair trial in the case;
when it is considered that the administration of pure Carbolic Acid seventy-six. drachms and
Iodine thirty-two drachms produced so little effect on the organisms, it will appear to be
evident that their use as remedical agents in this disease is of little practical value. From
October 1st to the 4th no organisms were detected in the blood, the uneasiness passed off,
and no further effect of the medicine was noticeable. On the morning of the 4th October,
a few hæmatozoa were discovered in the blood, and it was consequently decided to again
adopt treatment with Cinchona Alkaloids and Arsenic. Accordingly Cinchona Alkaloids 3iss
and Arsenic grs. iv were given twice during the day, and these doses were continued until
the evening of the 6th, when they were increased to two drachms and five grains respectively,
and these doses were continued until the evening of the 10th, when they were again
increased to two and a half drachms and six grains respectively, and continued until the
evening of the 14th, when they were increased to three drachms and seven grains, and on
the evening of the 16th, the Arsenic was increased to eight grains. The disease continued
to steadily progress during this time, and very little effect was produced upon the tempera-
ture.
The hæmatozoa during the period of the latter course of treatment were few for the
first four days, then absent for two days, again being few for four days, numerous for one,
again few for one day and then absent for four days from the blood, when death took place.
RECORDS OF URINE.
Animal—Grey Australian Gelding, No. LXX, date, September 24th.
Disease—Surra,
naturally acquired.
Date.
Sep, 24
25
2G
27
28
29
30
Oct. 1
2
3
4
5
6
7
8
9
10
11
13
13
14
15
16
17
18
19
Quantity.
...
...
...
...
...
Colour.
Turbid
orange
Turbid orange ...
Turbid orange
Turbid orange
Viscid, greenish yellow .
Viscid, greenish yellow.
Turbid, brownish black.
Turbid, viscid, bright
yellow.
Turbid, viscid, bright
yellow.
Turbid, viscid, bright
yellow.
Turbid, viscid greenish
yellow.
Viscid, turbid orange ...
Viscid, turbid orange ...
Viscid, turbid, greenish
yellow.
Viscid, turbid,
dirty
orange.
Viscid, turbid, greenish
yellow.
Turbid, viscid orange ...
Turbid, viscid orange ..
Turbid, viscid orange...
Turbid, viscid orange...
Turbid, viscid orange ...
Viscid, clear orange ...
Viscid, turbid yellow ...
Viscid, turbid, reddish
yellow
Turbid, viscid orange...
Turbid, viscid orange...
Re-action.
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ...
Alkaline ..
Sp.
Gravity.
1,030
1,030
1,032
1,0:33
1,030
1,030
1,040
1,018
1,020
1,026
1,034
1.038
1,032
1,038
1,012
1,050
1,042
1,040
1,040
1,031
1,030
1,032
1,038
1,029
1,030
1,028
Albumen.
No albumen.
No albumen.
No albumen.
No albumen.
No albumen.
No albumen.
No albumen.
A trace
A trace
A trace
A trace
No albumen.
No albumen.
Faint trace .
No albumen.
A1bumen
l/34th
A trace
Absent
A trace
A trace
A trace
...
l/22nd
l/20th
A trace
..
l/28th
1/20th
Phos-
phates.
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ...
No ..
No ..
No ..
No ..
Remarks.
Carbonates and oxalates of lime, no casts.
Caibonates and oxalates of lime, no casts.
Carbonates and oxalates of lime, no casts.
Carbonates and oxalates of lime, no casts.
Carbonates and oxalates of lime, no casts.
Carbonates and oxalates of lime, no casts,
Carbonates and oxalate crystals, no casts.
Small amount of carbonates, no casts.
Small amount of carbonates, no casts.
Increase in the amount of carbonates, no casts.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casta.
Carbonates and oxalates of calcium, no casts.
Carbonates and a considerable quantity of
oxalates.
Carbonates and oxalates of calcium, no casts.
Carbonates and a few oxalate of calcium, no
casts.
Carbonate and oxalate of calcium crystals.
Carbonates and oxalates of calcium, no casts.
Carbonates and oxalates of calcium, no casts.
B 1086—8 ap