xxxvi
It was decided to try the effect of large doses of Quinine, and for this purpose 3ss was
administered at noon; previous to the dose being given, the pulse was 56. Resp. 32. Half an
hour later the animal showed no symptoms and was quietly feeding. Temp. 1. P.M. 40.4°C.
Pulse 60. Resp. 40. The animal appeared to be suffering from head-ache. At 2-10 P.M.
the respirations had fallen to 32 per minute and the pulse to 22. At 4 P.M. the animal
appears dull and the breathing is somewhat peculiar; it first takes eight or nine shallow
respirations and these are followed by a deep sonorous one; pulse 48. Resp. 45. At
4-20 P.M. Temp. 39.8°C. Pulse 50. Resp. 24. At 6 P.M. 39.3°C. Pulse 50. Resp. 24.
The animal appears quite easy and is feeding well. Twelve grains of Arsenic were given
during the twenty-four hours, in water.
18th.—The animal appears bright and healthy, the petechia on the right conjunctival
membrane is very faint in colour, and is disappearing fast. Temp. A.M. 39.3°C. Pulse 48,
Resp. 30. The hæmatozoon is absent from the blood. Temp. 1 P.M. 39.8°C. Urine, turbid,
lemon-coloured. Sp. Gr. 1,010. Alkaline, no albumen, no casts, Carbonates and Oxalates of
Calcium. Temp. 5 P.M. 39°C. Pulse 44. Resp. 24. One dose of Quinine 3v was adminis-
tered at noon, and two doses of the Liquor Arsenicalis in water during the twenty-four
hours.
19th.—The condition of the animal remains the same. Temp. A.M. 38.6°C. Pulse 48.
Resp. 24. Administered Quinine 3vi at 9 A.M. The hæmatozoa are few in the blood,
but only one hænatozoon was found in two specimens of blood. Temp. 1 P.M. 39.6°C.
Urine, turbid, lemon-coloured. Sp. Gr. 1,004. Alkaline, albumen absent, crystals of Car-
bonate and Oxalate of Calcium. Temp. 5 P.M. 39.4°C. Pulse 48. Resp. 28. Two doses of
Liq. Arsenicalis were given in water.
20th.—-The animal appears bright, but notwithstanding this, œdema has appeared along
the under-surface of the abdomen, and the sheath is swollen. Temp. A.M. 39.6°C. Pulse 56.
Resp. 32. There are a few hæmiatozoa in the blood. Temp. 1 P.M. 40°C. Urine, turbid,
viscid, greenish yellow in colour. Sp. Gr. 1,034. Alkaline, no albumen, crystals of
Carbonate , but no Oxalate of Calcium. Temp. 5 P.M. 39.6°C. Pulse 46. Resp. 28. Six
drachms of Quinine and gr. xii of Arsenic were given during the twenty-four hours in
one dose.
21st.—The animal appears in the same condition as yesterday, but there are several
bright-red petechia; on the conjunctival membranes. The œdema on the under-surface of
the abdomen has not extended. The appetite is good, and the faxes quite normal in
character. Temp. A.M. 39.4°C. Pulse 64. Resp. 20. There are a few hæmatozoa in the
blood. Temp. 1 P.M. 40.l°C. Urine, turbid, viscid, yellow in colour. Sp. Gr. 1,028.
Alkaline, no albumen, no phosphates. Temp. 5 P.M. 39.6°C. Pulse 60. Resp. 32. Six
drachms of Quinine and gr. xii Arsenic were given in water during the twenty-four hours.
22nd.—This morning the animal looks perfectly healthy, with the exception of the
slight œdema on the lower portion of the abdomen, in front of the sheath. The petechia;
have entirely disappeared from the conjunctivæ, and the visible mucous membranes are
pale but clear. Temp. A.M. 89.4°C. Pulse 56. Resp. 24. There are still afew hæmtozoa
in the blood. Temp. 1 P.M. 40°C. Urine, turbid, viscid, orange in colour. Sp. Gr. 1,020.
Alkaline, albumen absent, crystals of Carbonate and Oxalate of Calcium. Temp. 5 P.M.
39.8°C. Pulse 52. Resp. 32. The animal received Quinine six drachms and Arsenic
gr. xii during the twenty-four hours.
23rd.—The animal appears dull and is slowly losing condition. The pulse is weak
and thready; the œdema is present but has not increased in amount; the membranes
remain clear, but there are two small petechiæ on the right conjunctival membrane, the
appetite remains good and the fasces normal in character. Temp. A.M. 39.2°C. Pulse 52.
Resp. 28. The hæmatozoa are few in the blood. Temp 1 P.M. 39.8°C. Urine, turbid,
viscid, creamy yellow in colour. Sp. Gr. 1,046. Alkaline, no albumen, but crystals of
Carbonate and Oxalate of Calcium. Temp. 5 P.M. 39.2°C. Pulse 60. Resp. 24, Two doses
of Cinchona Alkaloids 3iii and Liq. Arsenicalis 3iss were administered during the twenty-
four hours.
24th.—The condition of the animal is unchanged; if anything, the œdema along the
belly has slightly increased in amount. The visible mucous membranes are clear and there
are no petechiæ on the conjunctivæ Temp. A.M. 39°C. Pulse 48. Resp. 24. The hæma-
tozoon is absent from the blood. Temp. 1. P.M. 39.4°C. Urine, turbid, yellow in colour.
Sp. Gr. 1,026. Alkaline, no albumen. Temp. 5 P.M. 39.5°C. Pulse 56. Resp. 32. Two
doses of medicine were administered during the twenty-four hours, the Arsenic being in-
creased to gr. viii in the evening.
25th.—The animal is exceedingly dull and semi-somnolent. The œdema has increased
on the under-surface of the abdomen, but the condition of the sheath remains unaltered.
Temp. A.M. 39.2°C. Pulse 52. Resp. 24. The hænatozoon is absent from the blood.
Temp. 1 P.M. 39.4°C. Urine, turbid, orange in colour. Sp. Gr. 1,026. Alkaline, contains
no albumen, crystals of Carbonate and Oxalate of Calcium. Temp. 5 P.M. 39°C. Pulse 48.
Resp. 24. The animal received two doses of medicine during the twenty-four hours.