19
mative nephritis, Treatment.—This animal was subjected to a treatment
consisting of Cinchona Alkaloids and Arsenic ; at a later date the former drug
had to be replaced by Quinæ Sulphatis, but as the latter had no influence on
the hæmatozoon in the blood, it was found necessary to go back again to the use
of Cinchona Alkaloids, The hæmatozoon was absent from the blood for a
period of twenty-six days, but owing to symptoms of Cinchonism supervening
the specific treatment had to be abandoned, and the animal succumbed on the
third day after its re-appearance in the blood.
Autopsy.—Body emaciated, total absence of œdema. Lungs, apices and free
edges of the organs, the seat of localized emphysema, sub-pleural ecchymoses.
Heart.—Blood-stained fluid in pericardial sac, extensive sub-pericardial extra-
vasations, sub-endocardial extravasations involving musculi-papillares of left
ventricle. Liver enlarged, tissue healthy. Spleen much enlarged, few sub-
capsular petechias. Kidneys, small circular extravasations dipping into the
cortical portion. Stomach, cuticular portion stained yellow, villous portion pre-
sented four Spiroptera tumors. Small intestines, localized areas of congestion
sub-mucous petechias. Large intestine, few patchæ of congestion and a few,
specimens of the Strongylus armatus. Bladder.—A patch of extravasation at
the fundus. Brain, &c, healthy in appearance, half an ounce of fluid in the
lateral ventricles.
No. LXXIII.— An Australian gelding was purchased by the Bombay Tram-
way Company on the 17th April 1892, aged 7 years. Fever developed 14th October
1892. A general eruption of Urticaria appeared on the 24th. Hæmatozoon
discovered in the blood on the 30th. Between the 3rd and the 8th November
the eruption re-appeared every morning but faded each evening. It again
re-appeared on the 13th well marked but gradually faded by midday on that
date. Finally the eruption broke out on December 9th and was more or less
marked daily until the 19th.
This animal was submitted on October 31st, during an intermission, to a
treatment consisting of the double Iodide of Mercury and Potassium in gradually
increasing doses, commencing with grains ii, and at a later date Quinæ : Sulph :
was added. During this period there was present continued fever with
marked intermissions at irregular intervals. As this drug proved incapable of
arresting the development of the hæmatozoon, Arsenic was substituted on the
22nd November when five grains were given in the evening, with a temperature
of 40.8°C. in the form of Liq : Arsenicalis in water. The temperature on the
morning of the 27th November registered 38°C, since which date, with two
exceptions, viz., on January 2nd and 3rd, 1893, it never reached 39°C. until
January 27th.
Autopsy.—Body somewhat emaciated ; absence of swelling and oedema.
The tissues of the body are all stained an orange colour. Thorax—Right pleural
cavity contained 3 ozs., the left 4 ozs. of a turbid, orange-coloured fluid. Lungs—
Right presented a variegated colour. Anterior lobule was the seat of emphysema.
Anterior portion of the organ measuring 7" X 5" x 2.5" the seat of consolidation,
and on section the capsules were divided off by a thin layer of jelly-like exuda-
tion. Some calcareous nodules could be felt on passing the hand over the posterior
portion of the organ. Left—Few nodules ; tissues on section fairly healthy in
appearance. Pericardial sac contained ten ounces of a turbid orange-coloured
fluid. Heart—Normal in size, external surface free from petechias, base sur-
rounded by yellow-coloured exudation." On section—Cavities free from sub-
endocardial extravasations. Valves, without alterations. Abdominal Cavity con-
tained 6 ozs. of a blood-stained fluid. Liver, small, signs of old perihepatitis ;
numerous small calcareous bodies. On section—Tissues dark chocolate in colour,
somewhat firm. Spleen—Normal in size ; a few sub-capsular petechias. Kidneys
presented a healthy appearance. Stomach, small ; villous portion contained a
Spiroptera tumour. Intestines presented a healthy appearance. Two small
specimens of the Strongylus Armatus were found in the caecum. Bladder,
contracted ; no change in the mucous membrane.
No. LXXIV.—A grey Arab gelding, aged, showed signs of fever on the
14th October 1892. These subsided and re-appeared on the 26th February. The