27
twenty-second day when it reached 36.1°C. There was only one day, the 9th,
after the appearance of the organism, during which the hæmatozoon was absent
from the blood during the whole course of the disease; but on several occasions
abortive attempts were made to disappear.
Autopsy.—Localized emphysema at the apices of the lung; the surfaces
were dotted over with sub-pleural extravasations of blood. Heart presented
numerous sub-pericardial and sub-endocardial petechiæ. The Liver and spleen
enlarged, small extravasations on the capsule of the latter. Kidneys presented
numerous round purple petechiæ on their cortical surfaces. Small intestines
presented a few petechiæ dotted over the surface of the mucous membrane. This
animal was subjected to subcutaneous injections, and on one occasion Oleum
Terebinthinæ was injected directly into the general circulation.
Horse No. XV.—Brown Country-Bred Galloway, aged. Inoculated on
the 30th January 1891 with 0.8 c. c. of blood directly into the Internal Jugular
Vein, taken from Horse No. XI during life. The latent period occupied six days.
The temperature rose from 37.5° C. to 39.1°C. on the evening before the appear-
ance of the organism in the blood, and from that date assumed the continued type
of fever accompanied by slight daily remissions and irregular periods of inter-
mission. The animal died on the thirty-fifth day of the disease, viz., 11th March
1891.
Autopsy.—Localized emphysema at the apices, and sub-pleural extravasations
of the lungs ; sub-pericardial and sub-endocardial extravasations involving the
heart, with congested and ecchymosed patches on the villous mucous membrane
of the stomach ; much enlarged liver and spleen, &c. This animal was at first
submitted to direct injections of Potass : Bichromate into the general circula-
tion, but owing to local complications, gastric ingestion was substituted for
the former method of administration of the drug.
Horse No. XVIII.—Chestnut Country-Bred Horse, aged. Inoculated sub-
cutaneously with 2.0 c.c. of blood taken from the heart of Horse No. XV,
10 hours P.M. on 12th March 1891. The latent period occupied 13 days. Tem-
perature normal for 12 days, rise of 1°C. corresponding with the appearance of
the hæmatozoon, between the 11th and 29th days of the disease ; continued fever
accompanied by a few remissions at irregular intervals was present. Swelling
of the sheath and effusion into the tunica vaginalis testis occurred on the 21st
day of the disease. The animal succumbed on the 29th day.
Autopsy.—Body slightly emaciated. (Edema of limbs, scrotum, sheath and
under-surface of abdomen. Lungs, localized emphysema at the apices ; some cal-
careous nodules. Heart presented externally, especially posteriorly, several
groups of sub-pericardial extravasations. On section.—Cavities free from sub-
endocardial extravasations except the left ventricle which presented a few,
mostly involving the musculi papillares. Liver small, old perihepatitis, especially
of right lobe. Few concretions. Spleen enlarged, but somewhat soft ; no sub-
capsular petechiæ. Kidneys healthy. Stomach small ; no pathological lesions..
Small and Large Intestines.—Healthy.
Horse No. XIX—Grey Country-Bred Horse, aged. Inoculated sub-
cutaneously with 2.0 c. c. of blood removed from the heart of Horse No. XV, 10
hours post mortem on 12th March 1891. The latent period occupied 9 days. A
gradual rise in the temperature took place from the day of inoculation to 41°C.
on the clay previous to the appearance of the hæmatozoon in the general circula-
tion, followed by a gradual fall of 3.4°C. to 37'6°C. on the second day of the
disease. The temperature then oscillated until the morning of the twelfth day
when it took on the type of continued fever accompanied with irregular periods
of intermission until death which took place on 15th May 1891, the fifty-sixth
day of the disease.
Autopsy.—Considerable exudation into the subcutaneous tissue of the chest,
abdomen and sheath. Peculiar areas of tissue in the lungs presenting a fine
reticulated structure. Sub-pericardial and sub-endocardial extravasations of the
heart. The deposition of a yellow or somewhat orange material on the surface
of the cuticular portion of the stomach.