ccii
CASE No. XL.—BROWN C. B. HORSE, aged, in fair condition.
12th August,
13th.—
14th.—
15th.—
Temp.
„
„
1891.
A.M.
„
„
—Temp.
35.7°C.,
35.6°C.
36.6°C.
A.M.
P.M.
„
„
—, P.M.
36.3.°C.
36.8°C.
37°C.
36.2°C.
Blood
„
„
healthy.
„
„
12th, noon.—Inoculated subcutaneously with .6 cc. of blood over the right shoulder,
taken from the Internal Jugular Vein of Horse No. XXXIV one and a quarter hours after
death. The injected blood contained very numerous hæmatozoa at the time of death.
16th.—The animal appears in good health; the visible mucous-membranes are somewhat
pale, but there are no petechiæ on the conjunctival membranes. The appetite is good, and
the evacuations natural in character. Temp. A.M. 36 . 5°C. There are no hæmatozoa present
in the blood. Temp. P.M. 36.4°C.
17th.—The general condition of the animal is unchanged. There is a small raised
tumour, circular in form, one inch in diameter at the seat of inoculation, which is tender on
manipulation. Temp. A.M. 36°C. Hæmatozoa not present in the blood. Temp. P.M.36.5°C.
18th.—This morning an Urticarial rash is present on the neck, and along either side of
the spinal column. It consists of circumscribed raised patches, oval or circular in form,
but there appears to be no irritation caused by it. The swelling at the seat of inoculation
has increased slightly since yesterday, and the tension and tenderness of the parts are more
pronounced. There are no petechiæ on the conjunctival membranes, and the animal
appears healthy; appetite good, evacuations normal. Temp. A.M. 36.2°C. Hæmatozoa
absent from the blood. Temp. P.M. 36.6°C.
19th.—The eruption is still present in the same position as noted yesterday. The swelling
at the seat of inoculation has . increased in size and now measures two inches in diameter.
Temp. A.M. 36.2°C. Hæmatozoa are absent from the blood. Temp. P.M. 37°C.
20th.—The general condition of the animal is good. The rash is still present on the
neck and shoulders. The swelling at the seat of inoculation has remained stationary as
regards size. Temp. A.M. 36.3°C. Hæmatozoa absent from the blood. Temp. P.M. 37 . 3°C.
21st.—This morning the eruption is gradually fading from the neck and shoulders of
the animal. The swelling and œdema together with the tension and tenderness at the seat of
inoculation have diminished during the night. The visible mucous membranes are clear and
healthy; the appetite good and the evacuations normal. Temp. A.M. 39°C. The hæmato-
zoa are numerous in the blood. Temp. P.M. 39.2°C.
22nd.—The swelling and œdema are still further reduced in amount. The eruption has
now totally disappeared. Temp. A.M. 39 . 6°C. Hæmatozoa very numerous in the blood.
Temp. P.M. 38.5°C.
23rd.—Condition unchanged. Temp. A.M. 38.1°C. Hæmatozoa swarming in the blood.
Temp. P.M. 38.5°C.
24th.—The swelling at the seat of inoculation is now only slightly raised, and the size
of a rupee. The conjunctival membranes still remain free from petechiæ. The appetite is
good and the evacuations normal. Temp. A.M. 38.1°C. The hæmatozoa are very numerous
in the blood. Temp. P.M. 38.7°C.
25th.—The animal appears somewhat weak this morning, and the heart has become
irritable. There are numerous small petechiæ on the nasal septum in the right nostril, and
several much larger ones on the ala of the left nostril. The appetite is maintained and the
evacuations appear healthy. Temp. A.M. 38.5°C. Hæmatozoa very numerous in the blood.
Temp. P.M. 37.7°C.
26th.—The animal fell at 2 A.M. and kept eating up to the last; death took place at
3 A.M.
AUTOPSY at 12 noon, nine hours after death.
The body is fairly well nourished; there is no swelling of the extremities.
Thorax.—No fluid in the pleural cavities, and no adhesions. The lungs present localized
emphysema at the apices, and along the inferior free edges. The pleural surfaces of both organs
dotted over with small, somewhat circular, extravasations of blood, dark in colour, from 1/5th
to 1/8th of an inch in diameter, and on passing the hand over the surface of the organs some
hard nodules can be felt, some lying superficially, others under a layer of , tissue. On sec-
tion, the tissues present a dark-red colour, but appear healthy ; the extravasations above
mentioned are found to be lying under the visceral pleuræ and involve the tissues beneath to
the distance of 1/12 th of an inch. The nodules are either hard calcareous bodies, or more
caseous and soft in structure, irregular in outline and lie at different depths below the surface
of the organs.
There is a small quantity of a straw-coloured fluid lying in the cavity of the pericar-
dium.