IV] LOUIS A. KLEIN, DAVID W. CRISMAN, AND JOHN W. MOOR 275
SUMMARY
Seven udder quarters, infected with staphylococci, with characteristics corresponding to those
of mastitis staphylococci, were given injections via the teat canal of a solution of penicillin in sterile,
normal saline solution. Four quarters were given 8 injections of 500 c.c. each at intervals of six
hours and 3 received 4 injections at intervals of 12 hours. Each dose contained 22,800 Oxford
units of penicillin.
Samples of milk were taken for laboratory examination immediately before the first injection,
at intervals of 12 hours during the injection period, and on the third sixth, tenth, and thirteenth
days following.
Laboratory examinations indicated that the samples from all of the quarters taken after the
first injection were free of the staphylococcus infection. The samples taken subsequently, up to
six and twelve hours after the last injection, were also free, but infection again developed on the
plates inoculated with samples taken from five quarters on the third or sixth day after the last injec-
tion. The original staphylococcus infection has apparently been destroyed in the two other quarters.
Both of these quarters received 8 injections.
The results indicate that the antibacterial action continued for twelve hours but 4 doses were
not sufficient to obtain a permanent effect.
REFERENCES
1 Florey, M. E., and Florey, H. W. (1941). General and local Administration of Penicillin. Lancet 1, 387
2 Report of the Committee on Chemotherapeutic and Other Agents, Div. of Med. Sci., Nat'l Research Council (1943).
Penicillin in the Treatment of Infections, a Report of 500 Cases. J.A.M.A. 122, 1217
3 Lyons, Champ (1943). Penicillin Therapy in Surgical Infections in the U. S. Army, a report J.A.M.A. 123, 1007
4 Frei, Walter: Milchdriise. Joest's Spez. Path. Anat. der Haustoere, 4 (1), 44
5 Fleming, Alexander (1941). Discussion on Chemotherapy and Wound Infection. Proc, Roy. Soc. Med. 34, 342
6 Heilman, D. H., and Herrell, W. E. (1943). Comparative Bacteriostatic Activity of Penicillin and Gramicidin
J. Bact. 34, 12
7 Minett, F. C. (1937). Studies on Bovine Mastitis, XII, Mastitis Due to Staphylococci. J. Comp. Path. and Therap.
50 (2), 101
8 Plastridge, W. N., Andersen, E. O., Williams, L. F., and Weirether, F. J. (1939). Infectious Bovine Mastitis. VII,
Characteristics of Udder Staphylococci. Storrs. Agric. Exper. Sta. Bull. 231
9 Chapman, G. H., Berens, C., Peters, A., and Curcio, L. (1934). Coagulase and Hemolysin Tests as Measures of
the Pathogenicity of Staphylococci. J. Bact. 28, 343
REVIEW
The Scotch Shorthorn—The herds of Scotland, England and Wales, 1945-46
By T. B. MARSON (Published by Macmillan & Co., Ltd., London. Price 2s.)
T HE Scottish Shorthorn Breeders' Association has published a description of every herd of
registered Scottish Shorthorns of any size in the United Kingdom so that intending purchasers
may conveniently survey the whole field of potential operations.
The compilation was entrusted to Wing Commander Marsden and he has succeeded in exhibiting
the stock of each member in such a way that it gives the reader, in a most interesting manner, a
knowledge of the farm and conditions under which each herd is maintained, an intimate glimpse of
the personality of the owner, a sample description of outstanding individual bulls and cows, the
numerical strength of the herd and other details.
It is, as the author says, 'a brief factual presentation of the salient features and characteristics
of the existing individual herds of pedigreed Scotch Shorthorns'. The interest of the book for
Indian readers may well lie mostly in the exhibition of the skill of the author and the printers, for
the breed is not one of those likely to suit us.
MGIPC—M—III-1-15—29-6-48—520.