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No. CVII.—Australian Gelding, aged 14 years, No. 536, belonging to the Bombay Tramway
Company. Animal first noticed to be ailing 23rd September 1894. Surra hæmatozoon discovered in
blood on the same date. The horse arrived at the Laboratory stables on September 25th, and the same
evening was placed on Arsenic (grs. iv) in the form of Liquor Arsenicalis. Fifty-two grains in all were
given ; the chemical had to be discontinued on account of symptoms of gastric irritation supervening. The
temperature varied between 38.3 °C. (100.9 °F.) and 40.2°C. (104.3 °F.)and rose at the time of death
which occurred on October 4th to 40.3°C. (104.5 °F).
Autopsy.—Body somewhat emaciated. Absence of œdema. Thorax.—Several ounces of a semi-
turbid fluid in the pleural cavities, no pleural adhesions. Lungs.—Localized emphysema of the outer
lobes and free borders, and sub-pleural ecchymoses dotted over the surfaces of both organs. There is con-
solidation of the posterior third of the left lung. On section the consolidated portion presents a dark
appearance, and the individual lobules are separated from each other by a layer of orange-coloured
jelly. The remaining portions of the organs are distended with air. Pericardium —The sac con-
tains several ounces of a semi-turbid fluid. Heart, considerably hypertrophied, weighs 7 lbs. 13 ozs.
Externally extensive dark-red coloured extravasation lying under the epicardium, and involving the
right ventricle, a second over the apex of the left ventricle. On section.— Right Auricle and Ventricle
walls thin and placid, contain black clots of blood. Left Ventricle contracted, walls hypertrophied.
Left Auricle healthy. A few ecchymoses involving the bases of the musculi-papillaris, and the flaps
of the valves. Abdominal cavity contains 20 ozs. of slightly turbid fluid, Liver weighs 22 lbs. ½oz.
nearly double natural size. Opalescent patches involving Glisson's capsule. On section certain amount
of blood exudes from cut ends of the vessels. Tissues dark in colour and firm. Spleen 3 lbs. 6 ozs.
nearly double normal size. Surfaces petechiated. Tissues firm. Kidneys enormously enlarged. Right
weighs 3 lbs. 3 ozs., the Left 3 lbs. 9 ozs. Capsules strip easily. Surfaces of both organs thickly
petechiated. On section cortical portion thicker than normal, Malphigian corpuscles stand out well
marked. Stomach distended. On section, Cuticular portion healthy, there is a patch of congestion,
involving the mucous membrane of the villous portion near the pylorus. Small intestine petechiated.
marked congestion of the mucous membrane throughout. Large, intestine healthy. Bladder ditto.
No. CVIII.—An Arab Entire horse, aged, forwarded for treatment by Messrs. Scott and Company,
Bombay. Previous history not obtained. The animal arrived at the Laboratory stables on the
morning of 25th September 1894, in poor condition, evidently suffering from Surra for a considerable
time, on the following day slight general urticaria was observed, and all the marked symptoms of the
disease, in addition sphincter ani relaxed and rectum patent. On the morning of the 27th September
the animal was subjected to a treatment consisting of Liquor Arsenicalis (grs. iv) in gradually
increasing doses, later the dose to be altered according to the condition of the patient. After 20 grains
of Arsenic had been administered the hæmatozoon disappeared from the blood, and up to the time of
death on November 20th, a period of 53 days, had not returned. In all 370 grains of the chemical
were given. The temperature varied between 36.6 °C. (97.9 °F) and 40.5° C. (104.9 °F.). When
the animal fell, chloroform was administered and death took place a few minutes later.
Autopsy.—Body well nourished, some œdema of the extremities. Thorax.—No pleural adhesions.
Cavities each contain about one ounce of an orange-coloured fluid. Right lung distended with air.
one large, dark-coloured extravasation 2"× 2.5" lying beneath the visceral pleura, on section blood found
to invade the tissues to a depth of one inch. Left lung healthy. Pericardium.—The sac contains
10 ozs. of a semi-turbid orange-coloured fluid. Heart small, weighs 2 lbs. 0¾ oz., organ healthy.
Kidneys.—Right weighs 1 lb. 8 ozs., left 1 lb. 6 ozs. Tissues healthy. Stomach small. On section,
cuticular portion healthy. Villous portion, mucous membrane presents red lines in streaks on its
surface. Intestines healthy. Bladder ditto. Brain ditto.
No. CIX.—Persian-Gulf Entire, belonged to G. Division, Bombay Police. This animal was stat-
ioned at Mahím for months, fever observed October 7th, 1894. Removed to Parel Veterinary Hospital
11th October, where the hæmatozoon was discovered in its blood, remained there until November 4th,
when it was sent to Poona. Received Laboratory Stables November 5th, l894. Surra of one month's
standing. On the evening of the 5th November the animal was subjected to a treatment consisting of
Liq. Arsenicalis (Arsenic grs. iv) twice during the 24 hours, the dose to be gradually increased, and later
diminished if necessary according to the condition of the patient. In addition Sulphate of Iron in 1
drachm doses was given mixed with the corn from the evening of the 3rd to the 26th December. Five
hundred and sixty-one grains of Arsenic were administered between 5th November 1894 and the 5th
January 1895. On the latter date the chemical had to be discontinued on account of symptoms of
gastric irritation. The temperature varied between a maximum of 40.4 °C. (104.7°F.), and a minimum
of 37.6 °C. (99.7 °F.), but at the time of death, January 15th, 1895, the 97th day of the disease it
ran up from 39 °C. (102.2°F.) to 41.4°C. (106.5°F.).
Autopsy.—Body well nourished, no œdema of extremities. Thorax.—No fluid in or adhesions of the
pleuræ. Lungs.— Right presents nothing abnormal, Left, seat of hypostatic congestion. Pericardium.—
Small quantity of an amber-coloured fluid in the sac. Heart weighs 6 lbs. 12 ozs. External surface
free from petechiæ. On section, Right Auricle and Ventricle contain fluid blood ; Left Auricle healthy,
Left Ventricle contracted, few sub-endocardial dotted over the bases of the musculi papillaris. Abdo-
minal cavity free from fluid. Liver very large, 17 lbs., signs of old perihepatitis. The individual
lobules are well marked, centre being dark, external zone light colour. On section much blood exudes
from the cut ends of the vessels. Spleen large, 3 lbs. 8 ozs., sub-capsular petechiæ. Tissues tolerably