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the 30th and midday on the 3rd November; and from the morning of the 4th, gradually rose, attaining
40.5°C. on the 7th, and 40.4°C. and 40.5°C. on the 12th and 13th respectively. It fell, however, nearly
2.5°C. on the morning of the day previous to death, but again registered 41.3°C. by midday on that date.
Death occurred at 2 A.M. on, the 16th November.
Autopsy at 10 A.M.—Body emaciated. Tissues all more or less tinged a yellow colour, and large
petechias are present on the conjunctivæ. Thorato, free from fluid and pleuritic adhesions. Lungs.
—The superior surfaces of the organs presented a variety of colouration varying from pink to reddish-
yellow, blue and purple. There were numerous circular-shaped sub-pleural extravasations especially
invading the posterior half of the left lung. The apices were the seat of localized emphysema, and there
was a wedge-shaped area of 6 or 7 square inches in extent symmetrically placed on the superior surface,
and anterior portion of both organs—eight inches from the apices. On section the consolidated portions
of lung were covered by a layer of yellow exudation which dipped down between the lobules for the
most part distinctly isolating one lobule from another. Fluid blood exuded from the cut surfaces of the
organ, especially the posterior portion, but to the naked eye the tissue presented a healthy appearance.
Pericardium contained two ounces of an amber-coloured fluid. Heart.—External surface presented
several patches of sub-pericardial extravasation, the most extensive being 1.5" × .75" in extent, which were
found to invade the muscular structure to a limited degree. On section, right side contained clots
which varied in colour from yellow, orange, red to green. Right auricle presented a healthy appear-
ance.* Right ventricle was the seat of numerous sub-endocardial extravasations. Left auricle presented
a healthy appearance. Left ventricle, walls hypertrophied, contained a few clots, and a few sub-endo-
cardial extravasations. Liver enlarged. Tissues appear healthy. Spleen enlarged, to more than three
times the normal size. The tissues were firm, and there were a few sub-capsular petechiæ. Kidneys
pale, but both organs presented a healthy appearance. Stomach.—Cuticular portion healtby. Villous
portion presented a tumour (Spiroptera) near the line of demarcation, otherwise healthy. Small
Intestines.—Numerous ecchymoses were dotted. over the surface of the whole length.of mucous mem-
brane. No ulceration. Cœcum healthy. Colon presented several patches of congestion. No ulceration.
Rectum healthy. Bladder healthy.
Two Guinea Pigs were inoculated with blood serum taken from the jugular vein of this animal 10
hours post mortem but the results were negative.
Details with regard to the swelling which occurred at the seat of inoculation.
Horse No. XXXIX.—Inoculated
subcutaneously with small quantity of fish blood containing
hæmatozoa, mixed with 0.6 per cent. salt solution. Swelling at the seat of inoculation appeared on the
second day and increased in size up to the 4th, when it measured 3.25 inches in diameter. It then re-
mained stationary until the 7th day, when it commenced to decrease. No hæmatozoa were observed in
the blood, but the animal succumbed on the 15th day after inoculation.
Horse No, XLIII.—This animal was inoculated with blood containing hæmatozoa, mixed with 0.6
per cent, salt solution. Swelling appeared at the seat of the injection on the 2nd day, and increased
during the following day. The swelling remained stationary as to size on the 4th, but commenced to
decrease on the 5th day.
Subcutaneous inoculation and re-inoculation with soiled fish blood.
Horse No. XLIX.—(i) Inoculated with fish blood containing the hæmatozoon; swelling at the seat
of inoculation appeared on the 2nd day, increased until the evening of the 3rd, then subsided, on the
5th day all signs of it had disappeared, (ii) Re-inoculated as in the first instance, swelling on the
2nd day. On the 3rd day diminished, and finally disappeared on the 5th.
Horse No. XLVII.—This animal was inoculated (i) with blood containing the hæmatozoon, mixed
with salt solution. Swelling at seat of inoculation appeared on the 2nd, and continues until the 4th even-
ing, then subsided, (ii). Re-inoculation as in first instance, swelling increased to 4th evening, and then
subsided. Slight thickening until the l8th day. (iii), . Inoculation with fish blood a third time. Con-
siderable swelling at seat of inoculation on 2nd day. Next day subsided. (iv). Inoculated with 1.0 c.c.
of Horse Surra blood swarming with hæmatozoa. A swelling 1 1/4 inches diameter, appeared on the 3rd day.
This had increased on the 5th day to 1" in length. Reduction in size and tension occurred on the 6th
day and hæmatozoa were first observed in the blood. The animal succumbed on the 20th day of the
disease.