148
firm. Kidneys.—Right weighs 21.5 and Left 22 grammes. Tissues present healthy appearance. Stomach
ditto, Bladder ditto.
Dog No. VIII.—Aged
four months, was given some blood clot to eat at 6 P.M. taken from the
heart of Bullock No. 13, which died of Surra on 16th December 1895. As up to the 30th December,
the temperature of the animal remained within normal limits, and the blood daily examined micros-
copically showed no signs of the Trypanosoma, re-inoculation was performed on the above date. One
cubic centimetre of blood containing a few hæmatozoa taken from the heart of Dog No. VI, directly
after death, was subcutaneously injected into the right inguinal region. The latent period occupied
eleven days. The maximum temperature recorded was 39.5°C. during the first paroxysm, during which
period the animal succumbed on January 4th, 1896, at 4 P.M.
Autopsy.—Immediately
after death. Body well nourished. Thorax contains no fluid, no pleural
adhesions. Lungs collapsed, petechiated. Pericardial
Sac contains 23 c.c. of a semi-opaque fluid.
Heart.—External
surface presents healthy appearance. On section no extravasations. Liver enlarged.
Tissues appear healthy. Spleen enlarged, convex surface petechiated, tissues
firm.
Kidneys.—Capsules
strip easily, surfaces petechiated. Stomach—Mucous membrane presents healthy appearance.
Bladder
ditto.
Dog No. IX.—Pariah
puppy, four months old, subcutaneously inoculated on the 29th December
1895, with 1.25 c.c. of blood containing hæmatozoa, taken from the jugular vein of Bullock No. 152
ante mortem, at Karnal, Punjab. The latent period occupied a period of five days. The maximum
temperature, 40.8°C. during the period of disease, was recorded during Paroxysm VI, and the minimum
35.2°C. during Paroxysm IX, shortly before death. During the case, the muzzle became swollen
between the 24th February and 3rd March; on the latter date there was increased lachrymation.
Opacity of the left cornea was first noted on the 15th March, and gradually increased, until on 27th of
that month the animal was blind of that eye. After the first appearance of the organism in the blood
the animal survived ninety-four days, made up of nine paroxysms lasting 46 days, and eight intermissions
lasting forty-eight days. Death took place on the 5th April 1896, at 8.50 A.M.
Autopsy—40 minutes after death. Body somewhat emaciated. Gelatinous swellings lying sub-
cutaneously on either side of the forehead and on each side of the jaws. Parotid and sub-maxillary
glands increased in size and hard to the touch. Thorax.—No fluid in the pleural cavities, no pleural
adhesions.Lungs pale pink colour, distended with air. Right presents 7 or 8 sub-pleural extravasa-
tions, circular in form and half inch in diameter, somewhat raised, dark brick red in colour. Left, free
from petechiæ. Pericardial Sac few c.c. of clear fluid. Heart—External surface free from pathological
changes. Internal surface, no sub-endocardial petechiæ, blood fluid. Abdominal cavity contains 35
c.c. of a semi-opalescent fluid. Liver large, presents. healthy appearance.
Gall bladder distended
with dark green bile. Spleen large, granular on surface, no petechiæ. On section tissues firm.
Kidneys appear healthy. Stomach no food, small quantity of a yellowish fluid, mucous membrane pale
in colour, two small ulcers invading mucous coat close to pyloric end of the organ. Mesenteric
glands
are somewhat enlarged, dark in colour, and matted together, the tissues lying superior to the kidneys
are œdematous, and contain a fair amount of gelatinous material. Intestines healthy. Bladder ditto.
Dog No. X.—A Pariah, about 12 months old, was subcutaneously inoculated in the inguinal region
with 0.5 c. c. of blood taken 1 hour post mortem from the heart of Dog No. VII. The latent period
occupied six days. The highest temperature, 40.8°C., was recorded during the one paroxysm which
lasted for 21 days, when death occurred. For the last five days of life the organisms were swarming
in the blood.
Dog No. XI.—A Pariah, aged two years, body-weight 16.140 kilograms, was inoculated subcuta-
neously at 5 A.M. on 28th October 1897 with 0.5 c.c. of blood drawn from the jugular vein of a Surra
horse, but during an intermission ; the Trypanosoma was therefore absent. The latent period occupied
six days. The maximum temperature, 41.0°C., was registered during the first paroxysm, the minimum
38°C. during the second intermission. The case lasted 28 days after the first appearance of the Trypa-
nosoma in the circulation. This period was made up of three paroxysms lasting 9, 3 and 14 days, and
two intermissions lasting one and one day respectively. Death took place on the 1st December 1897.
Autopsy at 11-30 A.M. Body-weight 14:31 kilograms, total loss 1.830 kilograms. Body slightly
emaciated, no subcutaneous swellings. Thorax—No pericardial fluid, no adhesions. Lungs collapsed,
small patches of emphysema dotted over Right lung. Left free. On section tissues somewhat dark, on
pressure frothy mucus exudes. Trachea contains frothy mucus. Trachea and lungs weigh 375
grammes. Pericardial Sac contains few cubic centimetres of fluid. Heart weighs 148 grammes. Both
sides of heart dilated, but externally no changes. On section cavities filled with dark firm clots, small
quantity of fluid blood drips from the clots. No sub-endocardial petechiæ. Abdominal cavity contains
no fluid. Liver large, weighs 808 grammes. On section tissues firm. Gall bladder distended with dark
green bile. Spleen much enlarged, weighs 305 grammes, tissues soft and semi-fluid.
Stomach.—Mucous
membrane, although pale, present a healthy appearance; few petechiæ at pyloric extremity.
Kidneys.—Right weighs 46, Left 48 grammes, capsules strip easily. On section cortical portion healthy,
pyramids petechiated. Intestines healthy. Bladder ditto.
Dog No. XII.—A Pariah, aged two and half years, body-weight 10.7, was subcutaneously inocu-
lated on 31st October 1897 with 0.6 c.c. of blood containing very numerous organisms, drawn from
the jugular vein of a Surra Horse at Kathgodam. The latent period occupied four and half days. The