51
firm. Kidneys.—Right 2 lbs 3½ ozs., Left 2 lbs. 5 ozs., capsule strips easily, on section tissues deeply
congested. Pyramidal tubes injected, Malphigian corpuscles deep red colour, clearly defined. Stomach
healthy. Large and Small Intestines ditto. Bladder ditto.
No. CX.—Persian-Gulf Entire Horse, aged 9 years, belonging to the Bombay Mounted Police
(No. 27) was purchased on the 24th September 1894, and kept in Bombay until November 4th. On the
27th October the animal was first observed to be ailing. In addition to corn, green grass was given as
fodder from 1st to the 21st October. The animal was received at the Laboratory stables on November
5th, at 7 A.M. On admission the animal presented usual symptoms of fever, the mucous membranes
are yellow in colour and petechiated, swelling and œdema of sheath, scrotum and under-surface of the
abdomen. Temperature 40.5°C. Pulse 64. Respiration 44.
On the evening of its arrival the animal was put on Arsenic (grs. iv) in the form of Liquor Arseni-
calis in gradually increasing doses. After 23 grains had been administered the hæmatozoon
disappeared from the blood (November 8th), and between that date and death, which took place on
December 21st, did not re-appear.
On the 24th and 25th days of the Intermission the temperature rose to 39.5°C., and it was thought
likely that the organism would return, but on the following day (26th) it again fell to 38.°C. Between
the date of admission and death, the animal's temperature oscillated between 41°C. (105°F.) and37.8°C.
(100.2°F). Three hundred and twenty-one grains of Arsenic were administered in all, but for nine days
previous to death, the medicine was discontinued on account of bladder symptoms intervening.
Autopsy.—Body well nourished, no œdema or swelling of the limbs, &c.
Thorax.—No fluid present in the pleural cavities, but there are adhesions present, the result of an
old pleurisy. Lungs.—Right healthy, Left seat of hypostatic congestion. Pericardium—the sac
contains two drachms of an amber coloured fluid. Heart weighs 4 lbs. 8 ozs., external surface of the
organ petechiated especially bordering on the inter-ventricular sulie. On section the cavities present a
healthy appearance. The valves are stained yellow in colour. Spleen 2 lbs. 4½ ozs. Tissues present
healthy appearance. Kidneys weigh—Right 1 lb. 3¼ ozs., Left 1 lb. 4¼ ozs. Externally the organs pre-
sent a mottled appearance on section. Malphigian corpuscles are of a dull red hue and stand out pro-
minently. Stomach.—Cuticular portion presents one fairly large and four small ulcers near the line of
demarcation, the mucous membrane of the villous portion is also congested. Large and Small
Intestines ditto. Bladder.—The mucous membrane of bladder extensively ulcerated. Ulcers covered
with urinary deposits resembling 'Fuller's earth.' Other portions dark red in colour.
No. CXI.—Persian-Gulf Entire Horse (No. 100), aged four years, belonging to the Bombay Mounted
Police, was stationed in and around the city from the 16th June until the 17th October, on which date it
was observed to be ailing. 20th October sent to Veterinary College, Parel, for treatment. An average
of 20 lb. of green grass was given as fodder between the 1st September and 21st October 1894. The
animal was received at the Laboratory stables on November 5th. On admission.—The visible mucous
membranes present a faintly yellow appearance, and there is an accumulation of semi-solid œdema in
front of the chest. Temperature 38.2°C. Pulse 48. Respiration 24. On the evening of its arrival the
animal was put on Arsenic (grs. iv) in the form of Liquor Arsenicalis, in gradually increasing doses.
After 43 grains of Arsenic had been administered the Surra hæmatozoon disappeared from the blood
(October 10th), and between that date and death on the 26th of December, only one organism was
observed, viz. December 8th. From the 26th to the 30th day of the intermission the temperature began
to rise, until it attained on the latter day 40°C. (104°F.) and one hæmatozoon was seen in several
specimens of blood. Between the date of admission and death the animal's temperature oscillated
between 40.7°C. (105.2°F.) and 37.4°C. (99.3°F.). Four hundred and eight grains of Arsenic were admi-
nistered in all, but the Arsenic was discontinued four days before death on account of gastric irritation.
Autopsy.—Body well nourished, no œdema of the extremities, &c.
Thorax.—No fluid in the pleural cavities or adhesion of the pleuræ. Lungs, slight emphysema of
the anterior lobes, otherwise healthy. Pericardium contains few ounces of an orange-coloured fluid.
Heart weighs 4 lbs. 11 ozs.; external surface dotted over with numerous small dark-coloured petechiæ,
lying under the epicardium. On section, Left Ventricle presents one extravasation, dark in colour, lying
beneath one of the curtains of the auriculo-ventricular valve. Abdominal cavity free from fluid.
Liver weighs 13 lbs. 3½ ozs. There are numerous calcareous nodules dotted about on the anterior
and posterior surfaces of the organ, numerous lymphatic vessels are mapped out on the convex surface,
and there are signs of old perihepatitis present. On section tissues of a deep red colour, few calcareous
nodules dotted over the cut surfaces. Stomach —Cuticular portion pale ; villous portion, mucous mem-
brane considerably congested, and at the junction of the two there is a thin line of ulceration. Spleen
weighs 1 lb. 6¾ ozs., convex surface dotted over with spots of a brick-red colour, while on the concave
surface there are enlarged lymphatic vessels, which contain a clear transparent fluid. On section tissues
dark in colour but firm Kidneys. — Right weighs 1 lb. 11 ozs.; the Left 1 lb. 8¾. External surfaces
of organs petechiated. On section tissues dark in colour and vessels injected. Small Intestines.—
Superficial ulceration on the surface of mucous membrane, extending down the gut for 6 inches from
the pyloric orifice. Small patches of congestion are dotted over the mucous membranes throughout its
whole length. Colon.—Mucous membranes yellow in colour, also patches of congestion on its surface.
Bladder is distended with orange-coloured urine, and there are some ecchymoses round the neck of
the organ.