98
Autopsy.—Body emaciated, extremities and sheath swollen and
œdematous.
Thorax.—Numerous
extravasations lying under the parietal pleuræ on the inner surface of the ribs, but not on the interven-
ing muscular substance. Trachea.—Few extravasations on the inner surface lying on the cartilaginous
rings. Lungs.—Right apex, seat of localized emphysema, sub-pleural extravasations over the whole organ,
semi-solid patch of tissue at the base. Left apex for a distance of two inches dark-red in colour,
consolidated, localized emphysema of the anterior portion of the organ, sub-pleural extravasations.
Pericardium.—This cavity contained six ounces of deeply blood-stained fluid. Heart —Reddish-orange-
coloured gelatinous exudations surrounded the base of the organ. Large sub-pericardial extravasations,
one five inches in length on the external surface of the right ventricle, a second one but small invading
the left. On section, the right auricle presented a few small sub-endocardial extravasations, exceed-
ingly well marked and numerous in the right ventricle. The left auricle also contained a few, but the
left ventricle presented a similar condition to the right, with this exception that the extravasations
principally involved the musculi papillares. Abdominal Cavity.—The posterior surface of the diaphragm
is dotted over with extravasations, as also the small and large intestines. Spleen slightly enlarged,
dotted over with sub-capsular petechiæ. Liver small, signs of old perihepatitis, tissue invaded by calcare-
ous bodies. Kidneys pale extravasations on the inner surface of the pelvis, varying in size.
Stomach.—
Cuticular portion was dotted over with yellow flakes ; villous portion presented a large patch denuded of
its epithelial lining and of a rose colour, and also a raised lump 1.75"×.75" which on section was found
to contain a recent dark-coloured blood clot, lying on the muscular coat. Small
Intestines.—Eight
feet from the pylorus, several ulcers were found oval in shape and 3/4 inch in length occupying the seats
of Peyers patches and in the ileum patches of congestion and near the ileococeal valve several cicatrices.
Large Intestine.—A few scattered petechiæ. Parasites.—One specimen, a female specimen of "strongylus
armatus". Bladder.—Internal
surface the seat of numerous and extensive extravasations, giving to it
a dark, almost black, colour. Brain.—Superficial
veins distended, lateral ventricles large and contained
45 c.c. of fluid.
Horse No. XXXVII.—
Chestnut Country-Bred, aged. Inoculated subcutaneously on the 10th August
1891 with 0.7 c.c. of blood, six and half hours post-mortem but containing very numerous hæmatozoa
previous to death, taken from the jugular vein of horse No. XXXV. The latent period occupied five
days. Slight swelling and œdema followed at the seat of inoculation on the day following the injection
of blood, and remained until the hæmatozoon was found in the general circulation. The temperature
remained sub-normal until the evening before death when it commenced to rise, and at the time of death
on the following morning was 38.2°C.
Autopsy.—Body
emaciated. Lungs.—Apices and free borders were the seat of a localized emphy-
sema, sub-pleural extravasations, early form of pneumonia at the bases of the organs.
Peri-
cardium.—The
cavity contained little or no fluid. Heart.—The base of the organ together with
the large vessels were the seat of much yellow-coloured exudation. There were numerous sub-
pericardial extravasations especially along the course of coronary vessels. On section, the right
ventricle presented an almost black colour from the general sub-endocardial extravasation; this condition
in a modified way existed in the left ventricle, and a few sub-endocardial ecchymoses were observed in the
auricles. Liver.—Old
perihepatitis, otherwise healthy. Spleen.—Small, but presented numerous and
extensive sub-capsular extravasations. Kidneys.—Embedded
in yellow-coloured jelly, stellate veins in-
jected. Stomach.—The cuticular portion normal in appearance, the villous portion presented several
round cupped ulcers, and numerous 'Spiroptera' lying between the rugœ. Intestines present a healthy
appearance. Brain.—Membranes pale, no extravasations on the surface of the convolutions, the cavity
of the lateral ventricles contained about three drachms of fluid.
(c) SUBCUTANEOUS INOCULATION WITH SOILED RAT'S BLOOD.
Result Negative—Horses
Nos. LVII, LII, XLIV.
Horse No. LVII.—Brown Country-Bred, entire, aged. Inoculated subcutaneously on the 14th
January 1892, with 2.0 c.c. of blood containing numerous hæmatozoa taken from the rat (Mus decumanus)
immediately after death. A raised tumour appeared at the seat of inoculation, which became tense and
hard, but not tender on manipulation. All trace of the swelling at the seat of inoculation disappeared
in the course of twenty-six days, but the blood was found healthy on microscopical examination, during
the period the animal was under observation. From first to last the animal presented an intermittent
type of temperature, which at one time varied as much as 3° C. between the evening and morning
readings. The animal presented symptoms of mal-assimilation of food, and was, therefore, destroyed.
Horse No. LII.—Black
Country-Bred, pony, aged. Inoculated subcutaneously on the 30th October
1891 with 2.0 c.c. of blood containing numerous hæmatozoa taken from the heart of two rats (Mus decu-
manus) immediately after death. Swelling and œdema followed at the seat of inoculation, and some
days later the tumour became tense and hard, and exceedingly tender on manipulation, accompanied by
a muco-purulent discharge from both nostrils. As on the 19th November all signs of swelling, &c., had.
disappeared from the seat of the previous injection, the animal was again inoculated with 2.0 c.c. of blood
containing hæmatozoa from a similar source. A slight yellowness of the membranes followed together
with a considerable amount of swelling and œdema at the seat of the second injection, but during the
whole period which elapsed between the 30th October and January 28th, 1892, no organisms were
discovered in the blood. The temperature on the morning of the 7th November registered 37.2° C. but