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No. CXII.—Grey Persian Gelding, aged 13 years (No. 61), was purchased by the Bombay Tramway
Company on the 26th November 1887. Animal first noticed to be ailing 31st October 1894. Hæmato¬
zoon discovered in the blood 7th November. The animal was received at the Laboratory stables on 9th
November. State on admission.—Animal very much fatigued, in fair condition. Visible mucous mem-
branes tinged an orange colour, conjunctivæ petechiated.
Skin hot, pulse accellerated and feeble.
Swelling and œdema of scrotum and under-surface of the abdomen. There is some swelling and œdema
of the fetlocks, but they are cool and not tender. Hæmatozoa very numerous in the blood. On the
evening of its arrival the animal was put on Arsenic (grs. iv), in the form of Liquor Arsenicalis, in gra-
dually increasing doses. After 24 grains had been administered, the hæmatozoon disappeared from the
blood (November 12th), and between that date and death, which took place on January 23rd, 1895, a
period of 73 days, did not re-appear. Arsenic to the amount of 539.5 grains was administered in all,
but no medicine was given for 13 days previous to death. On the 39th day of the intermission the
temperature commenced to rise and on the 40th day registered 40.5°C., when lymphangitis of the
near hind limb developed, and continued for some days. Some leeches were applied with success.
Between the date of admission and death the temperature oscillated between 40.5° and 37.0°C.
Autopsy.—Body
emaciated, œdema and swelling of the extremities. Thorax.—No fluid in pleural
cavities and adhesions of pleuræ.
Lungs.—Anterior
lobes seat of localized emphysema, otherwise healthy. Pericardium contains one
ounce of an orange-coloured fluid. Heart weighs 5 lbs. 3 ozs. Organ presents a healthy appearance.
Abdominal cavity free from fluid. Liver weighs 7 lbs. 4½ ozs., signs of old perihepatitis, and a few
calcareous nodules are dotted over both surfaces. On section, tissues appear healthy. Spleen. weighs
1 lb. 14 ozs., healthy. Kidneys.—Right weighs 1 lb. 5 oz., left 1 lb. 4 ozs., tissues healthy. Large and
Small Intestines healthy. Bladder ditto.
No. CXIII.—Persian-Gulf Entire horse, aged 5 years, belonging to the Bombay Mounted Police
(No. 41), was purchased on June 2nd, 1894, and was kept in Bombay until 2nd November, when it was
sent to the Veterinary College Hospital, Parel, and remained there until the 27th. Organism first
observed on the 8th November. The animal was received at the Laboratory stables on the 28th. On
admission.—Animal in fair condition, ordinary symptoms of fever present, visible mucous membranes
injected, no conjunctival petechiæ. Slight œdema of the fetlocks. Temperature 39.5°C. Pulse 48.
Respiration 24. Hæmatozoon absent from the blood. On the evening of its arrival the horse was put
on Arsenic (grs. iv) in the form of Liquor Arsenicalis, in gradually increasing doses. After 33 grains
had been administered the hæmatozoon disappeared from the blood (December 3rd), and between that
date and death on the 13th December, a period of 11 days, did not re-appear. On the third day of the
intermission the temperature registered 41.2°C., and then gradually fell, but just before death rose
from 37.1 to 38.9°C. One hundred and thirty-five and a half grains of Arsenic were given in all.
Autopsy.—Body emaciated, no swelling or œdema of the extremities, &c. Thorax.—Pleural
cavities
normal. Lungs.—Anterior lobes seat of emphysema, otherwise healthy. Pericardium.—Small
quantity
of a yellow-coloured fluid. Heart weighs 5 lbs. 3½ ozs. On section, lining membrane of cavities stained
yellow in colour, no petechiæ. Abdominal cavity free from fluid. Liver weighs 16 lbs. 15½ ozs., and
is considerably enlarged. Old perihepatitis, no nodules. Spleen, weighs 2 lb. 4½ ozs. Surface covered
with varicosed lymphatic vessels, yellow caseous masses in the course of the lumen of the vessels. On
section, tissues firm, on pressure caseous pus exudes from the blocked tubes. There are several caseous
glands in the hilum of the organ. Kidneys.—Right
weighs 1 lb. 12½- ozs., left 1 lb. 10½ ozs., tissues
healthy. Stomach distended with food.
On section, foul-smelling gas escapes. Cuticular portion
stained yellow. The mucous membranes of villous portion slightly congested. Three tumours produced
by Spiroptera megastoma.
Small Intestines present a healthy appearance. Bladder ditto.
No. CXIV.—Australian Entire horse, aged 5 years, belonging to the Bombay Mounted Police
(No. 58), was purchased on 6th June 1894, and kept in and around the city until November 21st, when
it was observed to be ailing. On the following day it was removed to the Veterinary College Hospital
for treatment, and the organism was discovered in the blood. The horse was received at the Laboratory
stables on November 28th. On admission.—In very poor condition, ribs visible, belly tucked up, and
there is considerable loss of flesh. Visible mucous membranes excessively pale and anæmic, no
petechiæ. Ordinary signs of fever, together with some swelling and œdema of fetlocks. Dung soft
and pultatious. Temperature 40°C. Pulse 64. Respiration 12. Hæmatozoa few in the blood. On the
evening of its arrival the animal was put on Arsenic (grs. iv) in the form of Liquor Arsenicalis in
gradually increasing doses. After 23 grains had been administered the hæmatozoon disappeared
from the blood (December 2nd), and between that date and death on the 12th December, did not re-
appear. On the morning of the 30th of November the temperature registered 37°C., but from that
date until the evening of the 10th December it gradually rose and registered 41.7°C. (107.06°F.), but
during this interval there were always remissions in the morning. In all 92.5 grains of Arsenic were
administered.
Autopsy.—Body considerably emaciated, some œdema of the lower extremities. Thorax.—No fluid
nor adhesions of the pleuræ. Lungs — Right antelobe consolidated. On section individual lobules
deep red in colour, separated by a thin layer of greenish coloured jelly. Remaining portion of lung
and left antelobe healthy. Pericardium contains several drachms of semi-turbid fluid. Heart
weighs 5 lbs. 11 ozs., healthy. Abdominal cavity contains 19.5 ounces of a turbid orange-coloured
fluid. Liver weighs 15 lbs. 6 ozs., enlarged, old perihepatitis. On section tissues deep red colour,
firm, few calcareous nodules. Spleen weighs 1 lb. 5½ ozs., petechiated. Tissues healthy on section.