Pituitary Disorders of Childhood [electronic resource] : Diagnosis and Clinical Management /
Kohn, Brenda.editor.
This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing's Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmic disease, CNS radiation, childhood cancer treatment and traumatic brain injury. Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary.
Part I. Embryologic and Genetic Disorders of the Pituitary Gland -- Genomics -- Genetics of Hypopituitarism -- Part II. Acquired Pituitary Disorders: Pituitary Tumors and Nonpituitary Sellar Masses -- Adamantinomatous Craniopharyngioma: Genomics, Radiologic Findings, Clinical, Prognosis -- Prolactinomas -- Cushing's Disease: Diagnosis and Treatment -- Surgery for Cushing's Disease -- Gigantism and Acromegaly -- TSH Secreting Pituitary Adenomas -- Molecular Predictors of Clinical Behavior in Pituitary Adenohypophysial Tumors -- Nonpituitary Sellar Masses and Infiltrative Disorders -- Part III. Posterior Pituitary Disorders -- Posterior Pituitary Disorders: Anatomy and Physiology; Central Diabetes Insipidus (CDI); Syndrome of Inappropriate Anti-diuretic Hormone (SIADH) -- Part IV. Functional Hypothalamic-Pituitary Hormone Deficiencies -- Congenital Hypogonadotropic Hypogonadism (Isolated GnRH Deficiency) -- Genetics of Delayed Puberty -- Hypothalamic Amenorrhea -- Part V. Neuro-opthalmic Diseases -- Neuro-ophthalmic Diseases and Endocrinologic Function -- Part VI. CNS Radiation -- CNS Radiation of Childhood CNS Tumors -- Part VII. Childhood Cancer Treatment -- Hypothalamic-Pituitary Dysfunction as a Late-Effect of Childhood Cancer, Brain Tumors and their Treatments -- Part VIII. Traumatic Brain Injury -- Pituitary Response to Traumatic Brain Injury.
This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing's Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmic disease, CNS radiation, childhood cancer treatment and traumatic brain injury. Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary.
Endocrinology .
Pediatrics.
Endocrinology.
Pediatrics.