Surgery in the Multimodal Management of Gastric Cancer [electronic resource] /
De Manzoni, Giovanni.editor.
Roviello, Franco.editor.
Siquini, Walter.editor.
Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment. Operative endoscopy and endoscopic ultrasonography are also discussed, as these now have an important role in both diagnostic work-up and palliative care of gastric cancer patients. Only a multidisciplinary approach involving the surgeon, gastroenterologist, and oncologist can produce the comprehensive and integrated overview that today constitutes a winning strategy for the optimization of results.What we hope we have achieved is a flexible, up-to-date, exhaustive publication, rich in illustrations and consistent with evidence-based medicine.
Description based upon print version of record.
Title page; Copyright page; Foreword; Preface; Table of contents; Contributors; 1 Epidemiology of Gastric Cancer and Screening Programs; 1.1 Incidence of Gastric Cancer and Related Mortality; 1.2 Temporal Trends in Gastric Cancer Incidence and Related Mortality; 1.3 Epidemiology of Gastric Cancer as a Function of Site and Histology; 1.4 Survival in Gastric Cancer Patients; 1.5 Primary and Secondary Prevention of Gastric Cancer; 1.5.1 Primary Prevention; 1.5.2 Secondary Prevention; References; 2 Etiopathogenesis of Gastric Cancer; 2.1 Introduction; 2.2 Tobacco Consumption and Dietary Habits
2.3 Helicobacter pylori Infection2.4 E-Cadherin Gene (CDH1) and Diffuse Gastric Cancer; 2.5 Microsatellite Instability and Oncogenic Mutations; 2.6 Conclusions; References; 3 Lymphatic Spread, Lymph Node Stations, and Levels of Lymphatic Dissection in Gastric Cancer; 3.1 Lymphatic Systems of the Stomach; 3.1.1 The Anatomy and Regional Lymph Nodes of the Stomach; 3.1.2 Physiological Lymphatic Drainage from the Stomach; 3.2 Patterns of Lymph Node Spread in Gastric Cancer; 3.2.1 Lymphatic Spread in Adenocarcinoma of the Upper Third of the Stomach
3.2.2 Lymphatic Spread in Adenocarcinoma of the Middle Third of the Stomach3.2.3 Lymphatic Spread in Adenocarcinoma of the Lower Third of the Stomach; 3.2.1 Skip Metastasis; 3.3 Levels of Lymphatic Dissection; References; 4 Pathologic Classifications and Staging Systems; 4.1 Morphology; 4.1.1 Advanced Gastric Cancer; 4.1.1.1 Macroscopic Aspects; 4.1.1.2 Histological Types; 4.1.1.3 Carneiro Classification; 4.1.2 Early Gastric Cancer; 4.1.2.1 Macroscopic Aspects; 4.1.2.2 Histological Types; 4.1.2.3 Histochemical and Immunohistochemical Aspects
4.2 Cytochemical,Genetic, and Molecular Alterations4.3 Other Microscopic Types of Carcinoma; 4.4 The American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) TNM Staging System; 4.4.1 Primary Tumor (T); 4.4.2 Regional Lymph Nodes (N); 4.4.3 Distant Metastasis (M); References; 5 Prognostic Factors and Score Systems in Gastric Cancer; 5.1 Introduction; 5.2 Tumor-related Prognostic Factors; 5.3 Patient-related Prognostic Factors; 5.4 Treatment-related Prognostic Factors; 5.5 Prognostic Scores; 5.6 How To Easily Calculate The GIRCG Prognostic Score; References
6 Preoperative Work-up: Endoscopy and Endoscopic Ultrasonography6.1 Introduction; 6.2 Diagnosis; 6.3 Staging; 6.4 Endoscopic Treatment of Early Gastric Cancer; 6.4.1 Endoscopic Mucosal Resection; 6.4.2 Endoscopic Submucosal Dissection; 6.4.3 Long-term Results; 6.5 Conclusions; References; 7 Preoperative Work-up and Assessment of Resectability; 7.1 Introduction; 7.2 Endoscopic Ultrasound; 7.3 Computed Tomography; 7.4 Fluorodeoxyglucose Positron Emission Tomography; 7.5 Magnetic Resonance Imaging; 7.6 Laparoscopy; References; 8 Resection Margins in Gastric Cancer; 8.1 Background
8.2 Treatment Options
Includes bibliographical references and index.
Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment. Operative endoscopy and endoscopic ultrasonography are also discussed, as these now have an important role in both diagnostic work-up and palliative care of gastric cancer patients. Only a multidisciplinary approach involving the surgeon, gastroenterologist, and oncologist can produce the comprehensive and integrated overview that today constitutes a winning strategy for the optimization of results.What we hope we have achieved is a flexible, up-to-date, exhaustive publication, rich in illustrations and consistent with evidence-based medicine.
Surgery.
Abdominal surgery.
Oncology  .
Surgical oncology.
Gastroenterology .
Surgery.
Abdominal Surgery.
Oncology.
Surgical Oncology.
Gastroenterology.