Inflammatory Breast Cancer: An Update [electronic resource] /
Ueno, Naoto T.editor.
Fink, Tamara.editor.
Inflammatory breast cancer is the most deadly subtype of breast cancer because it can spread to other organs despite of multidisciplinary approach. However, the molecular characteristic of this aggressive disease is yet to be established. This book is the one of the few textbooks that summarizes the latest information dated to inflammatory breast cancer. The uniqueness of this book is that it has summarized the latest molecular and mechanistic findings, which may lead to novel diagnostic tool or therapeutic approach to fight this deadly disease.
Description based upon print version of record.
Inflammatory Breast Cancer: An Update; Contents; Chapter 1: Introduction: Why IBC Now?; Chapter 2: Epidemiology of Inflammatory Breast Cancer; 2.1 Introduction and Definition of Inflammatory Breast Cancer; 2.2 IBC Coding at MD Anderson Cancer Center; 2.3 Epidemiologic Risk Factors; 2.4 MD Anderson Cancer Center IBC Registry; References; Chapter 3: Clinical Aspect of Inflammatory Breast Cancer: Diagnosis, Criteria, Controversy; 3.1 Introduction; 3.2 Clinical Characteristics; 3.2.1 History and Symptoms; 3.2.2 Physical Examination; 3.2.3 Differential Diagnosis; 3.2.4 Findings on Imaging
3.2.5 Role of Biopsy3.2.6 Staging; 3.3 Variability of Case Definition: An Ongoing Controversy; 3.4 Diagnostic Criteria: The Consensus Statement; References; Chapter 4: Inflammatory Breast Cancer Registry; 4.1 Background; 4.2 Study Plan; 4.2.1 Patient Selection; 4.2.2 Demographic and Clinical Information; 4.2.3 IBC Questionnaire; 4.2.4 Photographs of Breasts; 4.2.5 Imaging Data; 4.2.6 Blood Specimens; 4.2.7 Tissue Specimens; 4.2.7.1 Cohort I; 4.2.7.2 Cohort II; 4.2.8 Sample Shipping and Storage; 4.2.9 Use of Samples for Research; References
Chapter 5: Pathology: Histomorphometrical Features of IBC - Angiogenesis, Lymphangiogenesis, and Tumor Emboli5.1 Introduction; 5.2 Overview of the Studies of the Lymphovascular Embolus of IBC; 5.3 Significance of the Studies; 5.4 Highlights of These Studies; 5.5 Details of the Studies; 5.5.1 MARY-X In Vitro Spheroidgenesis Provides Insights into Tumor Emboli Formation In Vivo; 5.5.2 MARY-X In Vitro Spheroidgenesis Is Associated with Unique Proteolytic Processing of E-cadherin
5.5.3 The Unique Proteolytic Processing of E-cadherin During MARY-X In Vitro Spheroidgenesis Is Mediated by Specific Cellular Proteases5.5.4 The Unique Proteolytic Processing of E-cadherin During MARY-X In Vitro Spheroidgenesis Is Further Supported by Correlative Levels of the Respective Proteases; 5.5.5 E-cad/NTF1-3 and E-cad/CTF1-3 Differ in Their Subcellular Localization During In Vitro Spheroidgenesis; 5.5.6 Manipulation of the Levels of E-cad/NTF1 by Calpain Inhibition Both Induces Spheroid Disadherence and Prevents In Vitro Spheroidgenesis
5.5.7 E-cad/NTF1 Contributes to In Vitro Spheroidgenesis and Increased Cellular Density5.5.8 The Stability of In Vitro Spheroidgenesis Is Dependent on Ca 2+; 5.5.9 In Vitro Spheroidgenesis Manifests Increased p120ctn, Bound E-cad/NTF1 and eIF4GI; 5.5.10 In Vitro Spheroidgenesis and In Vivo Emboli Formation Manifests a Unique and Enhanced Non-CAJ Membrane Distribution of E-cad/NTF1; 5.6 Discussion of the Studies; 5.7 Conclusions; References; Chapter 6: Imaging for the Diagnosis and Staging of IBC; 6.1 Introduction; 6.2 Mammography; 6.3 Sonography; 6.4 Magnetic Resonance Imaging
6.5 PET and PET-CT
Includes bibliographical references and index.
Inflammatory breast cancer is the most deadly subtype of breast cancer because it can spread to other organs despite of multidisciplinary approach. However, the molecular characteristic of this aggressive disease is yet to be established. This book is the one of the few textbooks that summarizes the latest information dated to inflammatory breast cancer. The uniqueness of this book is that it has summarized the latest molecular and mechanistic findings, which may lead to novel diagnostic tool or therapeutic approach to fight this deadly disease.
Medicine.
Cancer research.
Oncology  .
Biomedicine, general.
Cancer Research.
Oncology.