Chronic Obstructive Pulmonary Disease [electronic resource] : Co-Morbidities and Systemic Consequences /
Nici, Linda.editor.
ZuWallack, Richard.editor.
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide. By 2020, COPD is expected to be the fifth leading cause of disability and the third leading cause of death. COPD is associated with significant co-morbid illnesses including cardiovascular disease, pulmonary vascular disease, osteoporosis, depression and thoracic malignancies. In addition, COPD patients often have systemic manifestations of their disease, including peripheral muscle dysfunction, decreased activity levels and nutritional abnormalities, all of which contribute to poor functional status, decreased quality of life and increased health care utilization. Lack of recognition and understanding of the complex interactions of these common co-morbid conditions and systemic effects often contributes to sub-optimal care for patients with COPD. Comprehensive in covering the range of co-morbidities that often accompany COPD, Chronic Obstructive Pulmonary Disease: Co-Morbidities and Systemic Consequences provides a concise, evidence-based review of the problem and its systemic manifestations. All physicians interested in this growing disorder – from subspecialists to primary care providers –will find in this timely and informative title the practical, state-of-the art approaches needed to provide targeted, integrated care for patients with COPD.
Description based upon print version of record.
Chronic Obstructive Pulmonary Disease; Preface; Contents; Contributors; Chapter 1: Mortality in COPD: The Role of Comorbidities; Introduction; What Is the Overall Prognosis of COPD Patients?; What Do Patients with COPD Die from?; Possible Mechanistic Links Between COPD and CVD; Treatments that Modify Mortality in COPD; Treatment of Acute Exacerbations; Chronic Management of COPD and Survival; Smoking Cessation; Domiciliary Oxygen Therapy; Bronchodilators and Inhaled Corticosteroids; Statins and Beta-Blockers; Summary and Future Directions; References
Chapter 2: The Role of Systemic Inflammation in COPDIntroduction; Origins of Systemic Inflammation; Consequences of Systemic Inflammation; Cardiovascular Disease; Lung Cancer; Weight Loss/Muscle Wasting; Osteoporosis; Diabetes; Pathophysiology of Systemic Inflammation; Circulating Inflammatory Cells; Neutrophils; Lymphocytes; Monocytes/Macrophages; Inflammatory Mediators; Cytokines; IL-6; TNF- a; IL-1 b; Chemokines; Growth Factors; Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF); Transforming Growth Factor- b (TGF- b); Treatment; Inhaled Steroids; Anticholinergics
Exercise/Pulmonary RehabilitationSmoking Cessation; Statins; Summary; References; Chapter 3: The Disablement Process in COPD; Introduction; The Nomenclature of Disability; Assessing Disability in COPD; The Measurement of Exercise Capacity; Assessment of Spontaneous Physical Activity; The Background Effect of Ageing; Factors that Curtail Activity in COPD; The Trajectory of Disability; The Impact of Exacerbations; The Additional Effect of Co-morbidity on Physical Activity; Social and Cultural Aspects of Disability; Summary; Summary Points; References; Chapter 4: Cardiovascular Disease
IntroductionPrevalence of Cardiovascular Disease in Patients with COPD; The Impact of COPD on Cardiac Function; Treating Cardiovascular Function to Improve Outcome in COPD; Statin Treatment; Beta Blockers; Rehabilitation; Screening for Exercise Participation in COPD; Summary; References; Chapter 5: Osteoporosis; Introduction; Epidemiology; Risk Factors and Pathophysiology; Diagnostic Studies; Screening; Prevention; Pharmacologic Treatment; References; Chapter 6: Thoracic Malignancies; Introduction; Epidemiology; COPD as a Risk Factor for Lung Cancer
Emphysema, Chronic Bronchitis, and Lung Cancer RiskGender, COPD, and Lung Cancer; Asthma, COPD, and Lung Cancer; COPD and Thoracic Malignancies Aside from Lung Cancer; Pathophysiology of Lung Cancer Related to COPD; Genetics and Genomics of Lung Cancer in COPD; Molecular Pathogenesis of Lung Cancer Related to COPD; Novel Insights into Lung Cancer Pathogenesis in COPD; Clinical Aspects of Lung Cancer in COPD; Diagnosis of Lung Cancer in COPD; Preoperative Assessment; Perioperative Management of the Patient with COPD and Lung Cancer; Effects of Lung Cancer Surgery on Pulmonary Function in COPD
Effect of COPD on Complications and Prognosis After Lung Cancer Surgery
Includes bibliographical references and index.
Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality worldwide. By 2020, COPD is expected to be the fifth leading cause of disability and the third leading cause of death. COPD is associated with significant co-morbid illnesses including cardiovascular disease, pulmonary vascular disease, osteoporosis, depression and thoracic malignancies. In addition, COPD patients often have systemic manifestations of their disease, including peripheral muscle dysfunction, decreased activity levels and nutritional abnormalities, all of which contribute to poor functional status, decreased quality of life and increased health care utilization. Lack of recognition and understanding of the complex interactions of these common co-morbid conditions and systemic effects often contributes to sub-optimal care for patients with COPD. Comprehensive in covering the range of co-morbidities that often accompany COPD, Chronic Obstructive Pulmonary Disease: Co-Morbidities and Systemic Consequences provides a concise, evidence-based review of the problem and its systemic manifestations. All physicians interested in this growing disorder – from subspecialists to primary care providers –will find in this timely and informative title the practical, state-of-the art approaches needed to provide targeted, integrated care for patients with COPD.
Respiratory organs—Diseases.
Internal medicine.
Primary care (Medicine).
Pneumology/Respiratory System.
Internal Medicine.
Primary Care Medicine.
Respiratory medicine