Biomaterials for Tissue Engineering Applications [electronic resource] : A Review of the Past and Future Trends /
Burdick, Jason A.editor.
Mauck, Robert L.editor.
A concise overview of tissue engineering technologies and materials towards specific applications, both past and potential growth areas in this unique discipline is provided to the reader. The specific area of the biomaterial component used within the paradigm of tissue engineering is examined in detail. This is the first work to specifically covers topics of interest with regards to the biomaterial component. The book is divided into 2 sections: (i) general materials technology (e.g., fibrous tissue scaffolds) and (ii) applications in the engineering of specific tissues (e.g., materials for cartilage tissue engineering). Each chapter covers the fundamentals and reflects not only a review of the literature, but also addresses the future of the topic. The book is intended for an audience of researchers in both industry and academia that are interested in a concise overview regarding the biomaterials component of tissue engineering, a topic that is timely and only growing as a field.
Description based upon print version of record.
Biomaterials for Tissue Engineering Applications; Contents; Contributors; Chapter 1: Introduction; 1.1 Overview and Intent of the Book; 1.2 A Brief Overview of Tissue Engineering; 1.3 Closing Thoughts; References; Part I Biomaterials Technologies for Tissue Engineering; Chapter 2: Hydrogels in Tissue Engineering; 2.1 Introduction; 2.2 Basic Concepts; 2.3 Hydrogel Synthesis; 2.3.1 Chemical Crosslinking; 2.3.1.1 Covalent Crosslinking via Vinyl Groups; 2.3.1.2 Covalent Crosslinking via Carboxylate Groups; 2.3.1.3 Covalent Crosslinking via Amino Groups
2.3.1.4 Covalent Crosslinking via Hydroxyl Groups2.3.1.5 Covalent Crosslinking via Sulfhydryl Groups; 2.3.1.6 Covalent Crosslinking Using Orthogonal Click Chemistry; 2.3.1.7 Other Chemical Crosslinking Methods; 2.3.2 Physical Crosslinking; 2.3.2.1 Traditional Physical Crosslinking; 2.3.2.2 Physical Crosslinking by Molecular Self-Assembly; 2.3.2.3 Physical Crosslinking by Recognition Events; 2.4 Modulating Hydrogel Microstructure and Mechanical Properties; 2.4.1 Modulating Hydrogel Microstructure; 2.4.2 Engineering Hydrogels with Robust Mechanical Properties
2.5 Biodegradable and Bioactive Hydrogels2.5.1 Biodegradable Hydrogels; 2.5.1.1 Hydrolytically Degradable Hydrogels; 2.5.1.2 Externally Degradable Hydrogels; 2.5.1.3 Enzymatically Degradable Hydrogels; 2.5.2 Engineering Bioactive Hydrogels; 2.5.2.1 Bioactive Hydrogels with Immobilized Biological Motifs; 2.5.2.2 Bioactive Hydrogels with Soluble Growth Factors; 2.6 Conclusion and Future Directions; References; Chapter 3: Fibrous Scaffolds for Tissue Engineering; 3.1 Introduction; 3.2 Rationale for Using Fibers as a Scaffolding Material; 3.2.1 Favorable Structural Properties
3.2.2 Imitation of Extracellular Matrix3.2.3 Structural and Property Versatility; 3.3 Microfibrous Scaffolds; 3.3.1 Fabrication; 3.3.1.1 Polymer Extrusion; 3.3.1.2 Fiber Spinning; 3.3.1.3 Rapid Prototyping; 3.3.1.4 Various Textile Processing Techniques; 3.3.2 Biomedical Applications; 3.3.2.1 Wound Healing; 3.3.2.2 Cardiovascular Implant; 3.3.2.3 Musculoskeletal Tissue Engineering; 3.4 Nanofibrous Scaffolds; 3.4.1 Fabrication; 3.4.1.1 Phase Separation; 3.4.1.2 Self-Assembly; 3.4.1.3 Electrospinning; 3.5 The Electrospinning Technique; 3.5.1 Setup
3.5.2 Fabrication and Properties of Electrospun Nanofibrous Scaffolds3.5.2.1 Microstructural Control; 3.5.2.2 Macrostructural Control; Nonwoven, Randomly-Oriented Nanofiber; Aligned Nanofiber; 3.5.3 Biological Enhancement with Nanofibrous Scaffold; 3.5.4 Biomaterials for Nanofibrous Scaffolds; 3.5.5 Comparison Between Microfibrous and Nanofibrous Scaffolds; 3.5.6 Nanofibrous Scaffolds for Tissue Engineering Applications; 3.6 Future Directions; References; Chapter 4: Bioelastomers in Tissue Engineering; 4.1 Introduction; 4.1.1 Matrix Elasticity Impacts Cell and Tissue Function
4.1.2 Mechanical Stimulation Affects Cell and Tissue Development
Includes bibliographical references.
A concise overview of tissue engineering technologies and materials towards specific applications, both past and potential growth areas in this unique discipline is provided to the reader. The specific area of the biomaterial component used within the paradigm of tissue engineering is examined in detail. This is the first work to specifically covers topics of interest with regards to the biomaterial component. The book is divided into 2 sections: (i) general materials technology (e.g., fibrous tissue scaffolds) and (ii) applications in the engineering of specific tissues (e.g., materials for cartilage tissue engineering). Each chapter covers the fundamentals and reflects not only a review of the literature, but also addresses the future of the topic. The book is intended for an audience of researchers in both industry and academia that are interested in a concise overview regarding the biomaterials component of tissue engineering, a topic that is timely and only growing as a field.
Biomaterials.
Biochemical engineering.
Biomedical engineering.
Medicinal chemistry.
Polymers  .
Biotechnology.
Biomaterials.
Biochemical Engineering.
Biomedical Engineering and Bioengineering.
Medicinal Chemistry.
Polymer Sciences.
Biotechnology.