Reviews of Physiology, Biochemistry and Pharmacology [electronic resource] : Volume 162 /
Nilius, Bernd.editor.
Amara, Susan G.editor.
Gudermann, Thomas.editor.
Jahn, Reinhard.editor.
Lill, Roland.editor.
Offermanns, Stefan.editor.
Petersen, Ole H.editor.
M. Grunnet, B.H. Bentzen, U.S. Sorensen, J.G. Diness: Cardiac Ion Channels and Mechanisms for Protection Against Atrial Fibrillation. G.E. Pickard and P.J. Sollars: Intrinsically Photosensitive Retinal Ganglion Cells. T. Voets: Quantifying and Modeling the Temperature-dependent Gating of TRP Channels.  .
Description based upon print version of record.
Reviews of Physiology, Biochemistry and Pharmacology 162; Contents; Cardiac Ion Channels and Mechanisms for Protection Against Atrial Fibrillation; Introduction; Mechanisms and Aetiology of Arrhythmias; Triggers of Arrhythmias; Substrates of Arrhythmias; Atrial Fibrillation; Ion Channel Composition in Atria and Ventricles; Phase 0; Phase 1; Phase 2; Phase 3; Phase 4; Remodeling; Remodeling of Atria-Selective Currents; Cardiac Calcium Activated K+ Channels; Literature on SK Channels in the Atria; Discussion of Data on the Effects of Apamin in Atrial SK Channels; Management of AF
IKACh BlockersNTC-801; NIP-151 and NIP-142; IKur Blockers; AVE0118; DPO-1; S9947; KVI-020/WYE-160020; XEN-D0101 and XEN-D0103; Atria-Selective Sodium Channel Block; Ranolazine; Multichannel Blockers; Amiodarone; K201 (JVT-519); Tedisamil; AZD1305; Derivatives of Existing Drugs; Dronedarone; Budiodarone (ATI-2042); Celivarone; Novel Drugs Approved for the Treatment of AF; Vernakalant; Conclusion; References; Intrinsically Photosensitive Retinal Ganglion Cells; Early Hints of a Third Photoreceptor in the Mammalian Retina; The Convergence of Retinal Physiology and Internal Time Keeping
Melanopsin, the Photopigment of Intrinsically Photosensitive Retinal Ganglion CellsSCN-Projecting RGCs Are Intrinsically Photosensitive and Express Melanopsin; Melanopsin Is a Photopigment; ipRGC Physiological Responses to Light; ipRGC Response Kinetics; Photon Capture in ipRGCs Results in Membrane Depolarization; Chromophore Recycling and Bistability; Multiple ipRGC Subtypes with Widespread Axonal Projections; ipRGCs Targets in the Brain; ipRGC Intraretinal Signaling; ipRGCs Provide Excitatory Drive to Dopaminergic Amacrine Cells
ipRGCs Are Coupled to GABAergic Amacrine Cells via Gap JunctionsDifferent Types of ipRGC Have Different Central Targets; ipRGC Input to the Ventrolateral Preoptic Nucleus; ipRGC Input to the SCN and Seasonal Affective Disorder; ipRGCs and Retinal Disease; The Future; References; Quantifying and Modeling the Temperature-Dependent Gating of TRP Channels; 1 Introduction; 1.1 Thermosensation in Mammals; 1.2 A Definition of ThermoTRPs; 2 Parametrizing ThermoTRPs: Q10 and Thermal Threshold?; 3 Basic Characteristic of Prototype ThermoTRPs: TRPM8 and TRPV1; 4 Models of Thermosensitive Gating
4.1 Linear Models4.1.1 The Two-State Model; 4.1.2 Multistate Linear Models; 4.2 Allosteric Models; 4.2.1 The Monod-Wyman-Changeux-Type Allosteric Model; 4.2.2 The Dual-Allosteric Coupling Model; 5 What Is the Best Model?; 6 What Can We Learn from Structure-Function Studies (and What Not)?; 7 Conclusions and Outlook; References
Includes bibliographical references.
M. Grunnet, B.H. Bentzen, U.S. Sorensen, J.G. Diness: Cardiac Ion Channels and Mechanisms for Protection Against Atrial Fibrillation. G.E. Pickard and P.J. Sollars: Intrinsically Photosensitive Retinal Ganglion Cells. T. Voets: Quantifying and Modeling the Temperature-dependent Gating of TRP Channels.  .
Human physiology.
Human Physiology.
Reviews of physiology, biochemistry and pharmacology