Basis and Treatment of Cardiac Arrhythmias [electronic resource] /
Kass, Robert E.editor.
Clancy, Colleen E.editor.
Incorporating the information related to mechanisms and treatment of cardiac arrhythmia, this book discusses genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These approaches and implementations of anti-arrhythmic therapy derive from many decades of research.
Description based upon print version of record.
Incorporating the information related to mechanisms and treatment of cardiac arrhythmia, this book discusses genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These approaches and implementations of anti-arrhythmic therapy derive from many decades of research.
Includes bibliographical references and index.
History of Arrhythmias -- Pacemaker Current and Automatic Rhythms: Toward a Molecular Understanding -- Proarrhythmia -- Cardiac Na+ Channels as Therapeutic Targets for Antiarrhythmic Agents -- Structural Determinants of Potassium Channel Blockade and Drug-Induced Arrhythmias -- Sodium Calcium Exchange as a Target for Antiarrhythmic Therapy -- A Role for Calcium/Calmodulin-Dependent Protein Kinase II in Cardiac Disease and Arrhythmia -- AKAPs as Antiarrhythmic Targets? -- ?-Blockers as Antiarrhythmic Agents -- Experimental Therapy of Genetic Arrhythmias: Disease-Specific Pharmacology -- Mutation-Specific Pharmacology of the Long QT Syndrome -- Therapy for the Brugada Syndrome -- Molecular Basis of Isolated Cardiac Conduction Disease -- hERG Trafficking and Pharmacological Rescue of LQTS-2 Mutant Channels.
Pharmacology.
Cardiology.
Human physiology.
Pharmacology/Toxicology.
Cardiology.
Human Physiology.
Handbook of experimental pharmacology