Cardiovascular Complications in Cancer Therapy [electronic resource] /
Russo, Antonio.editor.
Novo, Giuseppina.editor.
Lancellotti, Patrizio.editor.
Giordano, Antonio.editor.
Pinto, Fausto J.editor.
This book is designed to provide a useful and comprehensive resource and state-of-the-art overview to readers about cardiovascular damage potentially induced by antineoplastic drugs. Thanks to more and more effective antineoplastic treatments, the survival of cancer patients is increasing at an exponential rate. However, the burden of related cardiovascular complications that affect morbidity and mortality are also on the rise. A new branch of cardiology, Cardio-Oncology, was developed to combat this trend. The aim of its conception is to prevent cardiovascular complications related to cancer therapy and to facilitate and avoid interruption of antineoplastic drugs due to the occurrence of cardiovascular damage. The text focuses on cardiovascular complications related to cancer treatment and reviews the pathophysiological mechanisms leading to cardiovascular toxicity related to various antineoplastic drugs. Diagnostic modalities for early diagnosis are also discussed, followed by preventive and therapeutic strategies. Cardiovascular Complications in Cancer Therapy serves as a valuable resource for residents, fellow physicians, medical oncologists, cardiologists, and general practitioners and all those who take care of these patients.
Introduction -- Mechanisms of Cardiovascular Damage Induced by Traditional Chemotherapy -- Molecular Mechanisms of Cardiovascular Damage Induced by Anti HER2 Therapies -- Cardiovascular Damage Induced by Radiotherapy -- Cardiovascular Damage Induced by Anti-VEGF Therapy -- Cardiovascular Damage Induced by Anti-BCR-ABL TKIs -- Heart Failure and Left Ventricular Dysfunction -- Coronary Artery Disease -- Peripheral Artery Disease and Stroke -- Valvular Heart Disease -- Arterial Hypertension -- Atrial Fibrillation in Cancer -- Management of QT Prolongation Induced by Anti-cancer Drugs -- Pulmonary Hypertension Induced by Anti-cancer Drugs -- Venous Thromboembolism -- Early Detection of Cardiac Damage -- Diagnosis of Cardiac Damage: Role of Stress Echo -- Early Detection and Monitoring of Vascular Damage -- Prevention and Clinical Management of Cardiovascular Damage Induced by Anticancer Drugs: Need for Early Biomarkers and Cardio- and Vasculo-Protection in Personalized Therapy -- Cardiovascular Damage in Clinical Trials.
This book is designed to provide a useful and comprehensive resource and state-of-the-art overview to readers about cardiovascular damage potentially induced by antineoplastic drugs. Thanks to more and more effective antineoplastic treatments, the survival of cancer patients is increasing at an exponential rate. However, the burden of related cardiovascular complications that affect morbidity and mortality are also on the rise. A new branch of cardiology, Cardio-Oncology, was developed to combat this trend. The aim of its conception is to prevent cardiovascular complications related to cancer therapy and to facilitate and avoid interruption of antineoplastic drugs due to the occurrence of cardiovascular damage. The text focuses on cardiovascular complications related to cancer treatment and reviews the pathophysiological mechanisms leading to cardiovascular toxicity related to various antineoplastic drugs. Diagnostic modalities for early diagnosis are also discussed, followed by preventive and therapeutic strategies. Cardiovascular Complications in Cancer Therapy serves as a valuable resource for residents, fellow physicians, medical oncologists, cardiologists, and general practitioners and all those who take care of these patients.
Oncology  .
Cardiology.
Oncology.
Cardiology.