35th Hemophilia Symposium Hamburg 2004 [electronic resource] : Epidemiology;Risk of Infections and Inhibitors in Hemophilia; Chronic lic Synovitis and Long-term Results of Orthopedic Treatment;Laboratory Diagnostics:Coagulation Factors; Inhibitors, Monitoring;Pediatric Hemostaseology;Free Lectures /
Hemophilia SymposiumCorporate Author
Hemophilia Symposium(35th :2004 :Hamburg, Germany)
Hemophilia Symposium
Scharrer, Inge.editor.
Schramm, Wolfgang.editor.
Motion analysis as introduced 2 years ago on a national basis effectively identifies individual functional disorders and provides a means for describing them on the basis of a score. Individual therapy planning is possible. More treatment tends to produce better function scores and thus helps to lower the strain on the joint. Further study is required in order to determine whether this reduces the incidence of bleeding. Knee function is age-dependent. Height, weight and sporting activity seem to be influencing factors.Demeanor,pain,fatigue and parental motivation do not seem to have an impact. The roll-and-glide pattern is not age-dependent and probably shows functional abnormalities of the knee.Functional benchmarking of the sites is possible but d- ficult because each site selects the children differently.Age differences also render an overall assessment difficult. Some sites performed negative screening so as to only test children with more severe problems,while other sites performed no such selection.In other sites,the only children to show up for motion analysis were those with well informed parents and who are always involved in all the other activities on offer too.
Description based upon print version of record.
Includes bibliographical references and index.
Epidemiology -- HIV Infection and Causes of Death in Patients with Hemophilia in Germany (Year 2003/2004 Survey) -- Hemophilia Registry of the Medical Committee of the Swiss Hemophilia Association - Update and Annual Survey 2004 -- Risk of Infections and Inhibitors in Hemophilia -- Update on the Safety of Clotting Factors, Mainly Regarding the Risk of Transmission of vCJD (Variant Creutzfeldt Jakob Disease) -- nvCJD and Blood Products in the UK -- Mutation Type Dependent Inhibitor Risk - a Single Center Study on 432 Patients with Severe Hemophilia A -- Inhibitor Incidence in Previously Untreated Patients (PUPs) with Hemophilia A and B. A Prospective Multi-Center Study of the Pediatric Committee of the German, Swiss and Austrian Society for Thrombosis and Hemostasis Research (GTH) -- ADVATE Inhibitor Risk Profile: 18 Months post-Licensure -- EACH-Registry: An European Registry for Acquired Hemophilia -- Elective Orthopedic Surgery for Hemophilia Patients with Inhibitors -- Chronic Synovitis and Long-term Results of Orthopedic Treatment -- Results after Total Knee and Hip Replacement in Patients with Hemophilia A - A Single Center Experience -- Motion Analysis Epidemiology in Hemophilic Children -- Radiosynoviorthesis in Hemophilic Arthropathy - A Single Center Experience -- Laboratory Diagnostics: Coagulation Factor, Inhibitors, Monitoring -- Individual Therapy of Hemophilia - New Laboratory Methods Considering Platelets -- Epitope Mapping during FVIII Inhibitor Elimination with Rituximab Reveals Conformational Epitopes on FVIII and Identifies Small Molecules Blocking Inhibitor and Targeting B Cells -- Lack of Factor VIII Expression Represents a Novel Mechanism Leading to Hemophilia A -- Pediatric Hemostaseology -- Effects of the Factor V G1691 A Mutation and the Factor II G20210A Variant on the Clinical Expression of Severe Hemophilia A (Motion analysis as introduced 2 years ago on a national basis effectively identifies individual functional disorders and provides a means for describing them on the basis of a score. Individual therapy planning is possible. More treatment tends to produce better function scores and thus helps to lower the strain on the joint. Further study is required in order to determine whether this reduces the incidence of bleeding. Knee function is age-dependent. Height, weight and sporting activity seem to be influencing factors.Demeanor,pain,fatigue and parental motivation do not seem to have an impact. The roll-and-glide pattern is not age-dependent and probably shows functional abnormalities of the knee.Functional benchmarking of the sites is possible but d- ficult because each site selects the children differently.Age differences also render an overall assessment difficult. Some sites performed negative screening so as to only test children with more severe problems,while other sites performed no such selection.In other sites,the only children to show up for motion analysis were those with well informed parents and who are always involved in all the other activities on offer too.
Hematology.
Orthopedics.
Pediatrics.
Hematology.
Orthopedics.
Pediatrics.