Aging and the Heart [electronic resource] : A Post-Genomic View /
Marín-García, José.author.
Cardiac aging, like aging in general, is a complex process. Numerous cellular and molecular changes contribute to the expression of the multiple phenotypes of aging, "the different faces" of cardiac aging. In this book, the genetic and molecular basis of cardiovascular aging will be discussed. In addition, a comprehensive assessment of the bioenergetic changes that occur in human and animal models of cardiac aging as well as current diagnostic and future therapeutic modalities will be undertaken. José Marín-García is Director, The Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey.
Description based upon print version of record.
Includes bibliographical references and index.
to a Post-Genomic View of Aging and the Aging Heart -- Post-Genomic View of Aging: Definitions, Theories and Observations -- Overview of Cardiovascular Aging -- Methodologies, Cardiac Phenotypes and Adaptation -- Molecular and Cellular Methodologies: A Primer -- Molecular and Cellular Phenotypes of Cardiovascular Aging -- Aging of the Cardiovasculature and Related Systems -- Aging of the Vasculature and Related Systems -- Aging and the Cardiovascular-Related Systems -- Cardiovascular Diseases in Aging -- Cardiomyopathy and Heart Failure in Aging -- Atherosclerosis, Hypertension and Aging -- Metabolic Syndrome, Diabetes and Cardiometabolic Risks in Aging -- Gender and Cardiovascular Diseases in Aging -- Cardiac Dysrhythmias and Channelopathies in Aging -- Genetics -- Genetics of Life Span: Lessons from Model Organisms -- Profiling the Aging Cardiovascular System: Transcriptional, Proteomic, SNPs, Gene Mapping and Epigenetics Analysis -- Therapies -- Translational Research: Gene, Pharmacogenomics and Cell-Based Therapy in the Aging Heart -- Nutrition and Exercise in Cardiovascular Aging: Metabolic and Pharmacological Interventions -- The Future of Aging Research -- Aging and the Frontier Ahead.
Cardiac aging, like aging in general, is a complex process. Numerous cellular and molecular changes contribute to the expression of the multiple phenotypes of aging, "the different faces" of cardiac aging. In this book, the genetic and molecular basis of cardiovascular aging will be discussed. In addition, a comprehensive assessment of the bioenergetic changes that occur in human and animal models of cardiac aging as well as current diagnostic and future therapeutic modalities will be undertaken. José Marín-García is Director, The Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey.
Cardiology.
Cardiology.