Cell Cycle in Development [electronic resource] /
Kubiak, Jacek Z.editor.
This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental program. Deciphering these adaptations is essential to comprehending how living organisms develop. The aim of this book is to review the best-known modifications and adaptations of the cell cycle during development. The first chapters cover the general problems of how the cell cycle evolves, while consecutive chapters guide readers through the plethora of such phenomena. The book closes with a description of specific changes in the cell cycle of neurons in the senescent human brain. Taken together, the chapters present a panorama of species - from worms to humans - and of developmental stages - from unfertilized oocyte to aged adult.
Description based upon print version of record.
CONTENTS; 1 Experimental Systems to Explore Life Origin: Perspectivesfor Understanding Primitive Mechanisms of Cell Division; 2 Evolution of Bet-Hedging Mechanisms in Cell Cycleand Embryo Development Stimulated by Weak Linkageof Stochastic Processes; 3 Mechanics and Regulation of Cell Shape Duringthe Cell Cycle; 4 The Spindle Assembly Checkpoint: Clock or Domino?; 5 Cell-Size-Dependent Control of Organelle SizesDuring Development; 6 The First Cell Cycle of the Caenorhabditis elegans Embryo:Spatial and Temporal Control of an Asymmetric Cell Division
7 EGG Molecules Couple the Oocyte-to-Embryo Transitionwith Cell Cycle Progression8 Cell Cycle in Ascidian Eggs and Embryos; 9 Regulatory Pathways Coordinating Cell Cycle Progressionin Early Xenopus Development; 10 Control of DNA Replication by Cyclin-Dependent Kinasesin Development; 11 Greatwall Kinase, ARPP-19 and Protein Phosphatase 2A:Shifting the Mitosis Paradigm; 12 The Role of RanGTP Gradient in Vertebrate OocyteMaturation; 13 Cell Cycle Control of Germ Cell Differentiation; 14 Protein Kinases and Protein Phosphatases that Regulate MeioticMaturation in Mouse Oocytes
15 Anaphase-Promoting Complex Control in Female MouseMeiosis16 Established and Novel Cdk/Cyclin Complexes Regulatingthe Cell Cycle and Development; 17 Function of the A-Type Cyclins During Gametogenesisand Early Embryogenesis; 18 Cell Cycle Adaptations and Maintenance of Genomic Integrityin Embryonic Stem Cells and Induced Pluripotent Stem Cells; 19 Cell Cycle Regulation by microRNAs in Stem Cells; 20 Cell Cycle Regulation During Proliferation and Differentiationof Mammalian Muscle Precursor Cells
21 Drosophila Neural Stem Cells: Cell Cycle Control of Self-Renewal,Differentiation, and Termination in Brain Development22 Control of Neuronal Ploidy During Vertebrate Development; 23 Cell Cycle Deregulation in the Neurons of Alzheimer's Disease; Index
Includes bibliographical references and index.
This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental program. Deciphering these adaptations is essential to comprehending how living organisms develop. The aim of this book is to review the best-known modifications and adaptations of the cell cycle during development. The first chapters cover the general problems of how the cell cycle evolves, while consecutive chapters guide readers through the plethora of such phenomena. The book closes with a description of specific changes in the cell cycle of neurons in the senescent human brain. Taken together, the chapters present a panorama of species - from worms to humans - and of developmental stages - from unfertilized oocyte to aged adult.
Developmental biology.
Cell biology.
Developmental Biology.
Cell Biology.
Results and problems in cell differentiation