Cancer [electronic resource] /
Bradbury, Rob.editor.
Reviews the advances in cancer chemotherapy research. This book is of interest to scientists engaged in drug research in the pharmaceutical industry, biotechnology and startup companies, academia and government institutions. It reflects a range of medicinal chemistry approaches to small molecule drugs, including anti-hormonal therapy.
Description based upon print version of record.
Reviews the advances in cancer chemotherapy research. This book is of interest to scientists engaged in drug research in the pharmaceutical industry, biotechnology and startup companies, academia and government institutions. It reflects a range of medicinal chemistry approaches to small molecule drugs, including anti-hormonal therapy.
Includes bibliographical references and index.
Overview -- Anti-hormone Therapy: Principles of Endocrine Therapy of Cancer -- Inhibition of Growth Factor Signaling by Small-Molecule Inhibitors of ErbB, Raf, and MEK -- Farnesyl Protein Transferase Inhibitors: Medicinal Chemistry, Molecular Mechanisms, and Progress in the Clinic -- Survival Signaling -- Progress in the Development of Agents to Control the Cell Cycle -- HDAC Inhibition in Cancer Therapy: An Increasingly Intriguing Tale of Chemistry, Biology and Clinical Benefit -- Development of Angiogenesis Inhibitors to Vascular Endothelial Growth Factor Receptor 2 for Cancer Therapy -- Novel Small-Molecule Inhibitors of Src Kinase for Cancer Therapy -- Bcr-Abl Kinase Inhibitors.
Medicinal chemistry.
Pharmacology.
Organic chemistry.
Molecular biology.
Medicinal Chemistry.
Pharmacology/Toxicology.
Organic Chemistry.
Molecular Medicine.
Topics in medicinal chemistry