Bacteria and Cancer [electronic resource] /
Khan, Abdul Arif.editor.
Bacterial infections cause substantial morbidity and mortality in cancer patients. These infections always remained enigmatic due to initial reluctance of cancer researchers in understanding their etiologic potential. Etiological association of bacteria with cancer gained credibility after discovery of carcinogenic potential of Helicobacter pylori. Moreover, other suspected associations including Salmonella typhi and gallbladder cancer, Streptococcus bovis and colon cancer, Chlamydia psittaci and ocular adnexal lymphoma and Chlamydia pneumoniae with lung cancer, etc. are looking for a legitimate appraisal to unravel their etiologic potential without prejudice.   In contrary, bacteria also show protective role in certain types of cancer. Certain agents derived from bacteria are successfully in practice for the management of cancer. The integrate association of bacteria and cancer is evident in both positive and negative aspects. The role of bacteria in cancer etiology and treatment is vigorously studied since last few years. Present book tries to provide current status of research undergoing in above direction, with the glimpses of future possibility for using microbiological knowledge in the management of this deadly killer. This book will interest specialists dealing with cancer associated infectious complications, researchers working in the field of cancer biology, teachers and scientists in the field of microbiology, biotechnology, medicine and oncology. The unique coverage of bacteriology and cancer association in both positive and negative way can usher into development of novel thrust area for microbiology students and experts.  .
Description based upon print version of record.
""Bacteria and Cancer""; ""Contents""; ""Chapter 1: Epidemiology of the Association Between Bacterial Infections and Cancer""; ""1.1 Introduction""; ""1.2 Oesophageal Cancer""; ""1.2.1 Viral, Parasitic and Fungal Infection""; ""1.3 Gastric Cancer""; ""1.3.1 Helicobacter pylori Infection""; ""1.3.2 Chronic Bacterial Overgrowth of the Stomach""; ""1.3.3 Pernicious Anaemia""; ""1.3.4 Surgery for Peptic Ulcer""; ""1.3.5 Possible Mechanism for Gastric Carcinogenesis in Instances of Hypochlorhydria""; ""1.4 Colorectal Cancer""; ""1.4.1 Faecal Bacteria Present in the Colon""
""1.4.2 Streptococcus bovis""""1.4.3 E. coli and Inflammatory Bowel Disease""; ""1.5 Gallbladder Cancer""; ""1.5.1 Gallstones""; ""1.5.2 Polya Partial Gastrectomy""; ""1.5.3 Infection with Salmonella typhi/paratyphi""; ""1.5.4 Infection with Helicobacter species""; ""1.6 Pancreatic Cancer""; ""1.6.1 Surgery for Peptic Ulcer""; ""1.6.2 Helicobacter species Infection""; ""1.6.3 Typhoid Carriage""; ""1.7 Bladder Cancer""; ""1.7.1 Schistosoma haematobium""; ""1.7.2 Tuberculosis""; ""1.8 Lung Cancer""; ""1.8.1 Pulmonary Tuberculosis""; ""1.8.2 Chlamydia pneumonia""
""1.8.3 Helicobacter pylori Infection""""1.9 Conclusion""; ""References""; ""Chapter 2: Gastric Cancer and Helicobacter pylori""; ""2.1 Introduction""; ""2.2 Pathophysiology of H. pylori Infection""; ""2.3 H. pylori Factors That Interact with the Host and Mediate Carcinogenesis""; ""2.3.1 CagA and the cag Pathogenicity Island""; ""2.3.2 The H. pylori Vacuolating Cytotoxin""; ""2.3.3 Outer Membrane Proteins""; ""2.4 Influence of Helicobacter pylori Infection on DNA Damage and Repair""; ""2.4.1 DNA Repair""; ""2.4.2 DNA Damage""; ""2.4.3 mtDNA Instability and H. pylori Infection""
""2.5 Pro-tumorigenesis Host Factors""""2.5.1 Human Gene Polymorphisms""; ""2.5.1.1 IL-1 Gene""; ""2.5.1.2 TNF-a, IL-10 and CXCL8 Genes""; ""2.5.1.3 Immune Response Genes""; ""2.5.2 b -Catenin in H. pylori Carcinogenesis""; ""2.5.3 Transactivation of EGFR by H. pylori""; ""2.5.4 H. pylori , Gastric Autoimmunity and Gastric Atrophy""; ""2.6 H. pylori and Immunity in MALT Lymphoma""; ""2.7 Conclusion""; ""References""; ""Chapter 3: Streptococcus bovis and Colorectal Cancer""; ""3.1 Colorectal Cancer and Microbial Agents""; ""3.2 Microbiological Characteristics of Streptococcus bovis""
""3.3 Association of SB with Colorectal Disease""""3.4 Potential Mechanisms in Carcinogenesis""; ""3.5 SB Serology in CRC Patients""; ""3.6 SB and CRC Risk""; ""3.7 Model for the Association of SB with CRC""; ""3.8 Conclusion""; ""References""; ""Chapter 4: Chlamydial Disease: A Crossroad Between Chronic Infection and Development of Cancer""; ""4.1 Introduction""; ""4.2 Chlamydiae""; ""4.2.1 Characteristics and Developmental Cell Cycle""; ""4.2.2 Chlamydia Strategies for Evading Host Immune Response""; ""4.2.3 Chlamydia Persistence and Chronic Infection""; ""4.2.4 Chlamydia and Apoptosis""
""4.3 Chlamydiae spp. and their Role in Cancer and in Chronic Diseases""
Includes bibliographical references and index.
Bacterial infections cause substantial morbidity and mortality in cancer patients. These infections always remained enigmatic due to initial reluctance of cancer researchers in understanding their etiologic potential. Etiological association of bacteria with cancer gained credibility after discovery of carcinogenic potential of Helicobacter pylori. Moreover, other suspected associations including Salmonella typhi and gallbladder cancer, Streptococcus bovis and colon cancer, Chlamydia psittaci and ocular adnexal lymphoma and Chlamydia pneumoniae with lung cancer, etc. are looking for a legitimate appraisal to unravel their etiologic potential without prejudice.   In contrary, bacteria also show protective role in certain types of cancer. Certain agents derived from bacteria are successfully in practice for the management of cancer. The integrate association of bacteria and cancer is evident in both positive and negative aspects. The role of bacteria in cancer etiology and treatment is vigorously studied since last few years. Present book tries to provide current status of research undergoing in above direction, with the glimpses of future possibility for using microbiological knowledge in the management of this deadly killer. This book will interest specialists dealing with cancer associated infectious complications, researchers working in the field of cancer biology, teachers and scientists in the field of microbiology, biotechnology, medicine and oncology. The unique coverage of bacteriology and cancer association in both positive and negative way can usher into development of novel thrust area for microbiology students and experts.  .
Cancer research.
Medical microbiology.
Oncology  .
Bacteriology.
Biotechnology.
Cancer Research.
Medical Microbiology.
Oncology.
Bacteriology.
Biotechnology.