Cell Fusion in Health and Disease [electronic resource] : II: Cell Fusion in Disease /
Dittmar, Thomas.editor.
Zänker, Kurt S.editor.
Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Vol 1 & Vol 2 leading experts will present up-to-date overviews about cell fusion in physiological and patho-physiological processes, which further covers the current knowledge about cell fusion-mediating molecules. Volume 1 deals with Cell Fusion in Health and will cover aspects of cell fusion in fertilization, placentation, in C. elegans, in skeletal muscle development and tissue repair, and the use of cell fusion for cellular reprogramming and cancer vaccine development. Volume 2 focuses on Cell Fusion in Disease with a particular emphasis on the role of cell fusion in cancer development and progression. Thus, Cell Fusion in Health and Disease Vol 1 & Vol 2 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion and beyond.
Description based upon print version of record.
""Preface""; ""Contents""; ""Contributors""; ""1 Introduction""; ""2 Horizontal Gene Transfers with or without Cell Fusions in All Categories of the Living Matter""; ""2.1 Acquisition and Horizontal Transfer of Vibrio cholerae Virulence Gene""; ""2.1.1 Hamburg 1892""; ""2.1.2 The Vibrio and the Disease""; ""2.1.3 The Phage and Its Genome""; ""2.1.4 The Hiding Place of the Original Cholera Virulence Genes""; ""2.2 Mimivirus and Its Companions""; ""2.2.1 Viruses and Toxins of Blooming Dinoflagellates""; ""2.2.2 Genes of the Mimivirus Shared with Its Phage and with Its Host Amoeba""
""2.3 Interviral (Virus-to-Virus) Gene Transfers""""2.3.1 Marek's Disease Herpesvirus""; ""2.3.2 Reticuloendotheliosis Virus Genomic Sequences in the Marek's Virus and in the Fowlpox Virus Genomes""; ""2.3.3 Herpesviruses Activate Latent Retroviruses""; ""2.3.4 Avian Herpesviruses Descend from Theropod Dinosaurs?""; ""2.4 Horizontal Gene Transfers in Archaea and Prokaryota""; ""2.4.1 The Darwinian Threshold (Woese)""; ""2.4.2 The Ancient Origin of ''Virulence Genes''""; ""2.4.3 A Selected Example of Speciation""; ""2.5 The Insertion of Adaptive Immunity Genes""; ""2.5.1 Retrotransposons""
""2.5.2 An Ancient Herpesvirus""""2.6 Horizontal Gene Gains in Eukaryota""; ""2.6.1 Viral Genes""; ""2.6.1.1 Bornavirus in Human Brain Cells""; ""2.6.1.2 Human Herpesvirus-6 in Human Telomers""; ""2.6.2 Horizontal Gene Transfers in Eukaryota""; ""2.7 Epithelial-to-Mesenchymal Transition of Human Cancer Cells""; ""2.7.1 Bacteria Inducing Inflammatory Cancers""; ""2.7.1.1 Helicobacter Pylori: Cancers of the Soil and Seed""; ""2.7.1.2 Bacteroides Fragilis: Inflammatory Carcinogenesis with or Without It""; ""2.7.2 The Epithelial-to-Mesenchymal Transformation""
""2.8 Horizontal Transfer of Proto-Oncogenes""""2.9 Horizontal Gene Transfers for the Treatment and Cure of Cancer""; ""2.10 Consequences""; ""2.11 Summary""; ""References""; ""3 Class III Viral Membrane Fusion Proteins""; ""3.1 Introduction""; ""3.1.1 Definition of Class III Fusion Proteins""; ""3.1.2 Viruses Encoding Class III Fusion Proteins""; ""3.1.3 The Multiple Roles of Class III Fusion Proteins""; ""3.2 Structural Features of Class III Viral Fusion Proteins""; ""3.2.1 Global Structural Organization of Class III Fusion Proteins""
""3.2.2 Domain Organization of Class III Fusion Proteins""""3.3 Functionally Important Regions of Class III Fusion Proteins""; ""3.3.1 Fusion Loops""; ""3.3.2 Membrane-Proximal (Stem) Regions and C-Terminal Domain (CTD)""; ""3.4 Molecular Basis of the Class III Type Proteins Fusion Mechanism""; ""3.4.1 Activation Triggers for Class III Viral Fusogens""; ""3.4.2 Structural Rearrangements of Class III Fusion Proteins""; ""References""; ""4 Human Trophoblast in Trisomy 21: A Model for Cell--Cell Fusion Dynamic Investigation""; ""4.1 Human Placenta and Trophoblast Differentiation""
""4.2 Membranes Proteins Involved in Human Trophoblast Fusion and Differentiation""
Includes bibliographical references and index.
Although cell fusion is an omnipresent process in life, to date considerably less is still known about the mechanisms and the molecules being involved in this biological phenomenon in higher organisms. In Cell Fusion in Health and Disease Vol 1 & Vol 2 leading experts will present up-to-date overviews about cell fusion in physiological and patho-physiological processes, which further covers the current knowledge about cell fusion-mediating molecules. Volume 1 deals with Cell Fusion in Health and will cover aspects of cell fusion in fertilization, placentation, in C. elegans, in skeletal muscle development and tissue repair, and the use of cell fusion for cellular reprogramming and cancer vaccine development. Volume 2 focuses on Cell Fusion in Disease with a particular emphasis on the role of cell fusion in cancer development and progression. Thus, Cell Fusion in Health and Disease Vol 1 & Vol 2 represents a state-of-the-art work for researchers, physicians or professionals being interested in the biological phenomenon of cell fusion and beyond.
Medicine.
Cell biology.
Cell membranes .
Biomedicine, general.
Cell Biology.
Membrane Biology.