Intracerebral Hemorrhage Research [electronic resource] : From Bench to Bedside /
Zhang, John.editor.
Colohan, Austin.editor.
The volume includes 75 papers which were presented at the Third International Conference on Intracerebral Hemorrhage, held in Rancho Mirage, California, in March 2010. The topics treated include animal models, pathophysiology of cerebral hemorrhage, experimental treatment for cerebral hemorrhage, cerebral hemorrhage clinical manifestations, prognosis of cerebral hemorrhage, and clinical management. The articles represent the recent advances in hemorrhagic brain injury research presented by highly respected laboratories around the world.
Description based upon print version of record.
Intracerebral Hemorrhage Research; Preface; Acknowledgement; Contents; Cerebral Hemorrhage Animal Models; History of Preclinical Models of Intracerebral Hemorrhage; Introduction; ICH Models; Microballoon Model; Collagenase Injection Model; Blood Injection Model; Large Animal Models; Monkeys; Canines; Pigs; Small Animal Models; Rabbits; Rats; Mice; Conclusion; References; Comparison of Different Preclinical Models of Intracerebral Hemorrhage; Introduction; Single Blood Injection; Microballoon-Induced Formation of ICH; Collagenase Injection; Comparison of the Collagenase and Blood Models
Hematoma SizeFunctional Outcome; Blood-Brain Barrier; Cell Death; Conclusion; References; Cerebral Amyloid Angiopathy-Related Microhemorrhages in Alzheimer's Disease: A Review of Investigative Animal Models; CAA-Associated Microhemorrhages; Non-Human Primate Model; Murine Model; Canine Model; Discussion; References; Multiparametric Characterisation of the Perihemorrhagic Zone in a Porcine Model of Lobar ICH; Introduction; Methods; Animal Preparation; Operative Procedure; Monitoring; Statistical Analysis; Results; Discussion; References; Developing a Model of Chronic Subdural Hematoma
IntroductionCharacterization and Origin of CSDH; Pathogenesis; Treatment and Complications; Animal Models; References; A Mouse Model of Intracranial Aneurysm: Technical Considerations; Introduction; Overview of Elastase-Induced Intracranial Aneurysm in Hypertensive Mice; Angiotensin II-Induced Hypertension; Blood Pressure Measurement; Stereotaxic Injection of Elastase; Conclusion; References; The Postpartum Period of Pregnancy Worsens Brain Injury and Functional Outcome After Cerebellar Hemorrhage in Rats; Introduction; Materials and Methods; The Animals and General Procedures
Model of Cerebellar HemorrhageCerebellar Water; Neurological Score; Animal Perfusion and Tissue Extraction; Hematoma Volume; Vascular Permeability; Western Blotting; Statistical Analysis; Results; Discussion; References; Hyperglycemia and Hemorrhagic Transformation of Cerebral Infarction: A Macroscopic Hemorrhagic Transformation Rat Model; Introduction; Materials and Methods; Middle Cerebral Artery Occlusion (MCAO) and Reperfusion Model; Hyperglycemia Model; Macroscopic Observation and TTC Staining; Morphological Assessment; Statistics; Results; Physiological Data
Brain Infarction and Hemorrhagic TransformationDiscussion; References; Hemorrhagic Transformation Induced by Acute Hyperglycemia in a Rat Model of Transient Focal Ischemia; Introduction; Materials and Methods; Animal Preparation and Middle Cerebral Artery Occlusion; Experimental Groups; BBB Integrity; Hemoglobin Measurement; Brain Water Content Measurement; Histology; Statistical Analysis; Results; Discussion; References; A Novel Preclinical Model of Germinal Matrix Hemorrhage Using Neonatal Rats; Introduction; Methods and Materials; Animal Groups and General Procedures
Experimental Model of GMH
Includes bibliographical references and index.
The volume includes 75 papers which were presented at the Third International Conference on Intracerebral Hemorrhage, held in Rancho Mirage, California, in March 2010. The topics treated include animal models, pathophysiology of cerebral hemorrhage, experimental treatment for cerebral hemorrhage, cerebral hemorrhage clinical manifestations, prognosis of cerebral hemorrhage, and clinical management. The articles represent the recent advances in hemorrhagic brain injury research presented by highly respected laboratories around the world.
Neurosurgery.
Neurology .
Neurosurgery.
Neurology.
Acta neurochirurgica