Chimeric antigen receptor T-cell therapies for cancer : a practical guide /
Lee, Daniel W.,editor.
Shah, Nirali,MD,editor.
Includes bibliographical references.
Introduction -- When to refer a patient for CAR-T cell therapy -- Optimizing the apheresis product -- CAR T cells: cell processing laboratory considerations -- Peri-CAR-T cell management -- Management of cytokine release syndrome -- Special considerations for ICU management of patients receiving CAR therapy -- Neurotoxicities after CAR-T cell immunotherapy -- Hematologic and non-CRS toxicities -- Response assessment and post-CAR-T cell therapy management -- Relapse management and role for consolidative hematopoietic stem cell transplantation following CAR-T cell therapy -- Promising chimeric antigen receptors for non-B cell hematological malignancies, pediatric solid tumors, and carcinomas -- CAR T cell therapy for CNS malignancies -- CAR 2.0: the next generation of synthetic receptor-based cellular therapy for cancer.
Description based on online resource; title from electronic title page (ClinicalKey, viewed December 19, 2019).
ClinicalKey
T cells
Tumor antigens.
Receptors, Chimeric Antigen
Neoplasms
Immunotherapy, Adoptive.
Receptors, Antigen, T-Cell.
Cell- and Tissue-Based Therapy.