Pocket Reference to Early Rheumatoid Arthritis [electronic resource] /
Emery, Paul.author.
Written by a world-renowned expert in rheumatology this book serves as a refresher for GPs and hospital doctors containing practical diagnostic and treatment advice. Reviews clinical developments and guidelines, and places them into everyday clinical practice Stresses the importance of early and aggressive treatment Concise but comprehensive whilst being loaded with illustrations including imaging examples all presented in pocket sized format   Rheumatoid arthritis (RA) is the most common and serious inflammatory arthritis, resulting in joint destruction, functional impairment and increased mortality.  The outcome of the disease, however, has improved considerably in recent years with the availability of effective therapies and the recognition that early intensive treatment strategies result in better outcomes. This book has been designed to increase physician awareness of the importance of early and intensive treatment – a key pharmaceutical strategy in rheumatoid arthritis.
Description based upon print version of record.
Title Page; Copyright Page; Table of Contents; Author biography; Chapter 1 Rheumatoid arthritis: an overview; Incidence; Aetiology and pathophysiology; Genetic factors; Environmental factors; Inflammation; Socioeconomic burden of rheumatoid arthritis; Economic burden for the patient; Impact of gender and economic status; Chapter 2 Diagnosis of rheumatoid arthritis; Typical clinical presentation; Radiological presentation; Diagnostic criteria; Differential diagnosis; EULAR recommendations for differential diagnosis; Diagnostic tests and evaluation of likelihood of progression
Chapter 3 The need for early diagnosis andintervention in rheumatoid arthritisUndifferentiated and early arthritis; The problems of early detection; Recognition of the presence of an inflammatory arthritis; Exclusion of other diseases; Estimation of the risk of persistence and progression; Evidence from clinical trials to support early intervention; Aggressive treatment in early arthritis; Early arthritis clinics; Nurse-led clinics; Outpatient management; Chapter 4 Treatment of rheumatoid arthritis; Goals of therapy; The importance of treatment to target; An overview of available medications
NSAIDs and COX-2 inhibitorsCorticosteroids; DMARDs; Biologic agents; TNF-a inhibitors; Comparisons with methotrexate; Combination therapy; Combination therapy with remission as a primary end-point; Speed of clinical response; The role of TNF-a inhibitors in early rheumatoid arthritis; Biologic agents aimed at targets other than TNF; Rituximab; Abatacept; Tocilizumab; Other biologics in development; Conservative vs aggressive treatment approaches; Overview of safety and tolerability profiles; NSAIDs and COX-2 inhibitors; Corticosteroids; Conventional DMARDs; Biologic agents
Chapter 5 Monitoring disease progression, treatmentresponse and outcomeJoint count measures; Laboratory measures; Clinical measures; Radiographic measures; Criteria for remission of rheumatoid arthritis; Recommendations for monitoring treatment response; Chapter 6 Imaging techniques in rheumatoid arthritis; What techniques are available?; Assessing radiographic progression; Joint abnormalities; Quantitative analysis of radiographs; Chapter 7 Guidelines; EULAR guidelines; BSR guidelines; NICE guidance; References
Includes bibliographical references.
Written by a world-renowned expert in rheumatology this book serves as a refresher for GPs and hospital doctors containing practical diagnostic and treatment advice. Reviews clinical developments and guidelines, and places them into everyday clinical practice Stresses the importance of early and aggressive treatment Concise but comprehensive whilst being loaded with illustrations including imaging examples all presented in pocket sized format   Rheumatoid arthritis (RA) is the most common and serious inflammatory arthritis, resulting in joint destruction, functional impairment and increased mortality.  The outcome of the disease, however, has improved considerably in recent years with the availability of effective therapies and the recognition that early intensive treatment strategies result in better outcomes. This book has been designed to increase physician awareness of the importance of early and intensive treatment – a key pharmaceutical strategy in rheumatoid arthritis.
Rheumatology.
Rheumatology.