Controversies in Aortic Dissection and Aneurysmal Disease [electronic resource] /
Bonser, Robert S.editor.
Pagano, Domenico.editor.
Haverich, Axel.editor.
Mascaro, Jorge.editor.
This book reviews the surgical management of patients with aortic disease, revealing many options open to cardiovascular specialists in this often controversial area of management. It reviews each controversy and provides clinical information for cardiac surgery, and discusses the spectrum of disorders and their management.   With the knowledge base in this discipline changing rapidly, Controversies in Aortic Dissection and Aneurysmal Disease meets an important requirement to consolidate the wide-ranging information on which clinicians must base their practice. It is directed towards surgeons, physicians, and healthcare workers involved in the care of patients requiring cardiac, cardiothoracic and cardiovascular surgery. This book will be an essential resource for these professionals looking to accelerate the translation of basic research findings into clinical study and practice.
Description based upon print version of record.
About the Editors; Preface; Acknowledgement; Contents; Contributors; Part I: Advance Recognition and Protection of Those at Risk of Acute Aortic Dissection; 1: The Clinical Genetics of Thoracic Aortic Disease; Introduction; Marfan Syndrome; Frequency, Inheritance and Diagnostic Criteria; Clinical Features; Molecular Pathogenesis; Patient Management and Treatment; Loeys-Dietz Syndrome; Clinical Features; Molecular Pathogenesis; Patient Management and Treatment; Recent Findings of New LDS Genes; Familial Thoracic Aortic Aneurysm; Differential Diagnosis Within the MFS/LDS Spectrum
Ehlers-Danlos Syndrome (EDS)Cutis Laxa; Bicuspid Aortic Valve Associated Aortopathy; Other Disorders Within the MFS/LDS Spectrum: Cardiovascular Features; Disorders Within the MFS/LDS Spectrum Without Major Aortic Involvement; Unexpected Findings: FBN1 mutations Leading to Opposing Phenotypes; References; 2: When Should Surgery Be Performed in Marfan Syndrome and Other Connective Tissue Disorders to Protect Against Type A Dissection?; Background; Method; Guidelines; Rationale and Supporting Data; Limits and Conflicting Data; Comment; Aortic Biomechanics; Rationale and Supporting Data
Limits and Conflicting DataComment; Use of Expected Normal Aortic Diameters; Rationale and Supporting Data; Limits and Conflicting Data; Comment; Aortic Growth; Rationale and Supporting Data; Limits and Conflicting Data; Comment; Aortic Geometry; Rationale and Supporting Data; Limits and Conflicting Data; Comment; Etiology of Aortic Pathology; Rationale and Supporting Data; Limits and Conflicting Data; Comment; The Strategic Decision Making Paradigm; Abbreviation; References; 3: The Aortopathy of Bicuspid Aortic Valves; Background;  Embryologic Development
Defining the Scope of the Problem: BAV Aortopathy Aortic Dissection;  Genetics;  BAV Aortopathy: Genes or Hemodynamics?;  Molecular Biology of BAV Aortopathy;  Hemodynamic Theory of BAV Aortopathy;  Imaging the Aortic Root;  Medical Therapy;  Surgical Replacement of the Aortic Root;  Conclusion; References; 4: Size Matters: Intervention Thresholds for Dissection Prophylaxis in the Ascending Aorta; Introduction;  Normal Diameters of the Ascending Aorta ;  Aortic Growth and Aging;  What Is an Abnormal Diameter? Echocardiographic Methods;  Aortic Size and MRI;  Aortic Size and CT
Aortic Growth and Pathologic Conditions When Can Aortic Dissection Occur?;  Aortic Dissection and BAV;  When Is Operation Indicated in Asymptomatic Patients? What do the Guidelines Say?;  Management and Follow-Up in Case of Aortic Dilatation;  Operative Treatment;  Genetic Counseling;  Conclusion; References; 5: The Exostent Versus Alternative Strategies: The Role of an External Support Sleeve in Aortic Prophylaxis; Introduction;  Prophylactic Aortic Surgery;  Aortic Root and Valve Replacement;  Valve Sparing Root Replacement;  External Aortic Root Support (Exostent);  Discussion
Future Developments
Includes bibliographical references at the end of each chapters and index.
This book reviews the surgical management of patients with aortic disease, revealing many options open to cardiovascular specialists in this often controversial area of management. It reviews each controversy and provides clinical information for cardiac surgery, and discusses the spectrum of disorders and their management.   With the knowledge base in this discipline changing rapidly, Controversies in Aortic Dissection and Aneurysmal Disease meets an important requirement to consolidate the wide-ranging information on which clinicians must base their practice. It is directed towards surgeons, physicians, and healthcare workers involved in the care of patients requiring cardiac, cardiothoracic and cardiovascular surgery. This book will be an essential resource for these professionals looking to accelerate the translation of basic research findings into clinical study and practice.
Medicine.
Medicine/Public Health, general.